Ishihara Yasuhiro 石原康宏

… Alternative Names

ISHIHARA Yasuhiro 石原康宏

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Researcher Number	80435073
Other IDs
Affiliation (Current)	2025: 広島大学, 統合生命科学研究科(総), 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 広島大学, 統合生命科学研究科(総), 教授 2019 – 2022: 広島大学, 統合生命科学研究科(総), 准教授 2012 – 2018: 広島大学, 総合科学研究科, 助教 2015: 広島大学, 大学院総合科学研究科, 助教 2011 – 2012: 広島大学, 大学院・総合科学研究科, 助教 2008: Tokushima Bunri University, 香川薬学部薬理学講, 助教 2007 – 2008: Tokushima Bunri University, 香川薬学部, 助教
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Basic Section 63030:Chemical substance influence on environment-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Transformative Research Areas, Section (IV) / Complex systems / Biological pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Natural medicines / Basic Section 63030:Chemical substance influence on environment-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach … More / Basic Section 42020:Veterinary medical science-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Hygiene and public health / Chemical biology / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals Less
Keywords	Principal Investigator ミクログリア / ケモカイン / 発達神経毒性 / 酸化ストレス / オリゴデンドロサイト前駆細胞 / 神経回路機能 / 化学物質 / 脳内炎症 / 神経毒性 / 発熱 … More / ミエリン / 脳スライス培養系 / 神経炎症 / 性差 / エストロゲン / マンガン / バルプロ酸 / 神経回路網形成 / エピジェネティクス / 行動異常 / 環境化学物質 / NADPH oxidase / AhR / 炎症反応 / 炎症 / マクロファージ / 芳香族炭化水素受容体 / MRI / ミトコンドリア / 活性酸素 / メチル水銀 / 再灌漑障害 / 再灌流障害 / 心筋梗塞 / チトクロムP450 … More Except Principal Investigator 脳内炎症 / てんかん / DHA / ドコサヘキサエン酸 / 小児 / 社会医学 / 化学物質 / ミクログリア / 脳波 / MRI / 五苓散 / 脳浮腫 / 漢方薬 / トリメチルスズ / 海馬 / ニューロステロイド / skin barrier disruption / ex vivo skin / air liquid exposure / fine particulate matter / IL-8 / CXCL1 / ケラチノサイト / 再構築ヒト皮膚モデル / PM2.5 / 便 / ヒト / 便中 / マイクロプラスチック / CAGE / レベチラセタム / 脳卒中 / 脂質代謝物 / 犬 / 特発性てんかん / 児脳発達 / 周産期 / 抗てんかん / 補完療法 / ビデオ脳波 / マウス / ペンチレンテトラゾール / 熱性けいれん / アラキドン酸 / 酸化ストレス / パーキンソン病 / 可溶性エポキシド加水分解酵素 / DHAジオール / 可用性エポキシド加水分解酵素 / 薬物代謝酵素 / チトクロームP450 / リゾホスファチジン酸 / 脱リン酸化活性 / 長鎖不飽和脂肪酸 / エポキシド加水分解酵素 / アレルギー / 分子疫学 / 抗体 / 樹脂 / プラスチック / 疾患モデル / FACS / サイトカイン / 重積発作 / 血液脳関門 / 浸潤 / プロトカドヘリン / 活性化因子 / 特異性 / 反応機構 / タンパク質カルボニル化 / ホスファターゼ / 膜透過性 / 遊走 / 乳がん細胞 / 特異的阻害剤 / 構造機能相関 / 細胞毒性 / 細胞遊走 / がん転移・浸潤 / スクリーニング / 阻害剤 / プロテインホスファターゼ / てんかん原性 / 側頭葉てんかんモデルマウス / 血管原性脳浮腫 / 予防 / BBB / 神経障害 / ＢＤＮＦ / 社会的孤独 / 飼育環境 / プロゲステロン / 神経保護作用 / トリブチルスズ / メチル水銀 / エストラジオール / 神経毒性 Less

Elucidation of the pathogenesis of idiopathic epilepsy in dogs based on lipid metabolic profiles and establishment of treatment methods
- Principal Investigator
  
  米澤智洋
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
発達神経毒性研究の新機軸：脳内ケモカインによるミエリン形成阻害Principal Investigator
- Principal Investigator
  
  石原康宏
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Hiroshima University
高齢者で急増する脳卒中後てんかん発症予防に有効な薬物療法の確立へ向けた基礎研究
- Principal Investigator
  
  小森理絵
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
脳スライスをジオラマ環境として用いたオリゴデンドロサイト前駆細胞の原生知能の解析Principal Investigator
- Principal Investigator
  
  石原康宏
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Hiroshima University
無痛分娩に伴う非感染性発熱と児の発達との関連性を解き明かす実験的アプローチPrincipal Investigator
- Principal Investigator
  
  石原康宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hiroshima University
Mechanism of action for aggravation of skin diseases under the exposure of fine particulate matter (PM2.5) to various skin barrier condition
- Principal Investigator
  
  河野まおり
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Osaka University
Uptake evaluation and biological effects by microplastic analysis in human feces
- Principal Investigator
  
  辻真弓
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  University of Occupational and Environmental Health, Japan
Basic research on complementary DHA intake therapy to reduce the risk of infant brain development
- Principal Investigator
  
  Itoh Kouichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
Analysis of bifunctional enzyme sEH in the brain
- Principal Investigator
  
  Oguro Ami
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Hiroshima University
エストロゲンとマンガン動態との関連に着目したマンガン神経毒性性差発現機構の解明Principal Investigator
- Principal Investigator
  
  石原康宏
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hiroshima University
Disruption of brain chemokine networks and impaired neural circuit formation due to developmental exposure to chemicalsPrincipal Investigator
- Principal Investigator
  
  Ishihara Yasuhiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Hiroshima University
Suppressive effects of GOREI-SAN (Kampo) for brain edema and inflammatory response in acute phase after status epilepticus
- Principal Investigator
  
  Kouichi itoh
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Tokushima Bunri University
Relationship between infant allergy prolongation and combined exposure to resin raw materials
- Principal Investigator
  
  Tsuji Mayumi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  University of Occupational and Environmental Health, Japan
Formation of abnormal neural circuit elicited by microglia with modulated gene expression exposed to environmental chemicalsPrincipal Investigator
- Principal Investigator
  
  Yasuhiro Ishihara
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
The mechanism of oxidative neuronal injury induced by methylmercury.(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Ishihara Yasuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
An attempt to develop novel CaM kinase phosphatase inhibitors that are effective for suppression of cancer metastasis with low cytotoxicity
- Principal Investigator
  
  Ishida Atsuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Hiroshima University
A new strategy for epilepsy therapy and Kampo: Focusing on preventing brain edema in basic research
- Principal Investigator
  
  Itoh Kouichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Tokushima Bunri University
The mechanism of generation of reactive oxygen species and oxidative neuronal injury induced by methylmercuryPrincipal Investigator
- Principal Investigator
  
  Ishihara Yasuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
Effect of housing conditions on neurotoxicity of chemicals
- Principal Investigator
  
  Yamazaki Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
Protective effect of neurosteroids on developmental brains
- Principal Investigator
  
  YAMAZAKI Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
Identification of the source of reactive oxygen species during heart reperfusion and application to pharmacotherapyPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Yasuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University

[Book] Neurosteroids: regional steroidogenesis. in 'Fifty Years of Cytochrome P450 Research.'2014
- Author(s)
  Yamazaki T, Ishihara Y., ed.Yamazaki H.
- Total Pages
  409
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-25340047
[Journal Article] 太陽光劣化繊維状ポリエチレンテレフタラートの呼吸器影響評価2024
- Author(s)
  石原康宏，岩本洋子，奥田知明，大河内博，鍋谷悠，河野まおり
- Journal Title
  
  大気環境学会誌
  
  Volume: 59
- Data Source
  KAKENHI-PROJECT-23K11436
[Journal Article] A simple air–liquid interface exposure system for exposing cultured human 3D epidermis and cornea to PM2.5 collected through cyclonic separation2024
- Author(s)
  Kono Maori、Takaishi Masayuki、Okuda Tomoaki、Fujihara Masashi、Noguchi Seisuke、Ishihara Yasuhiro
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 49 Issue: 2 Pages: 61-68
- DOI
  10.2131/jts.49.61
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Data Source
  KAKENHI-PROJECT-23K11436
[Journal Article] Microglial inflammatory reactions regulated by oxidative stress2023
- Author(s)
  Ishihara Yasuhiro、Itoh Kouichi
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 72 Issue: 1 Pages: 23-27
- DOI
  10.3164/jcbn.22-71
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04341
[Journal Article] Suppressive Effects of Docosahexaenoic Acid Intake on Increased Seizure Susceptibility after Growth Due to Febrile Seizures in Infancy2023
- Author(s)
  Kawano Shinji、Itoh Kouichi、Ishihara Yasuhiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 9 Pages: 1184-1193
- DOI
  10.1248/bpb.b23-00015
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06702
[Journal Article] Involvement of polycyclic aromatic hydrocarbons and endotoxin in macrophage expression of interleukin-33 induced by exposure to particulate matter2022
- Author(s)
  Ishihara N, Okuda T, Hagino H, Oguro A, Tani Y, Okochi H, Tokoro C, Fujii-Kuriyama Y, Itoh K, Vogel CFA, Ishihara Y
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 47 Issue: 5 Pages: 201-210
- DOI
  10.2131/jts.47.201
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07031
[Journal Article] Aryl Hydrocarbon Receptor Signaling Synergizes with TLR/NF-κB-Signaling for Induction of IL-22 Through Canonical and Non-Canonical AhR Pathways2022
- Author(s)
  Ishihara Yasuhiro、Kado Sarah Y.、Bein Keith J.、He Yi、Pouraryan Arshia A.、Urban Angelika、Haarmann-Stemmann Thomas、Sweeney Colleen、Vogel Christoph F. A.
- Journal Title
  
  Frontiers in Toxicology
  
  Volume: 3 Pages: 787360-787360
- DOI
  10.3389/ftox.2021.787360
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04341
[Journal Article] A CCR5 antagonist, maraviroc, alleviates neural circuit dysfunction and behavioral disorders induced by prenatal valproate exposure2022
- Author(s)
  Yasuhiro Ishihara, Tatsuya Honda, Nami Ishihara, Kaede Namba, Makiko Taketoshi, Yoko Tominaga, Mayumi Tsuji, Christoph F. A. Vogel, Takeshi Yamazaki, Kouichi Itoh & Takashi Tominaga
- Journal Title
  
  JOURNAL OF NEUROINFLAMMATION
  
  Volume: 19 Issue: 1 Pages: 195-195
- DOI
  10.1186/s12974-022-02559-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12182, KAKENHI-PROJECT-21K15247, KAKENHI-PUBLICLY-22H05698, KAKENHI-PROJECT-20H04341, KAKENHI-PROJECT-23K21755
[Journal Article] Involvement of the Microglial Aryl Hydrocarbon Receptor in Neuroinflammation and Vasogenic Edema after Ischemic Stroke2021
- Author(s)
  Tanaka Miki、Fujikawa Masaho、Oguro Ami、Itoh Kouichi、Vogel Christoph F. A.、Ishihara Yasuhiro
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 4 Pages: 718-718
- DOI
  10.3390/cells10040718
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05510, KAKENHI-PROJECT-20J10103, KAKENHI-PROJECT-20H04341
[Journal Article] FosL1 Is a Novel Target of Levetiracetam for Suppressing the Microglial Inflammatory Reaction2021
- Author(s)
  Niidome Kouji、Taniguchi Ruri、Yamazaki Takeshi、Tsuji Mayumi、Itoh Kouichi、Ishihara Yasuhiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 20 Pages: 10962-10962
- DOI
  10.3390/ijms222010962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04341, KAKENHI-PROJECT-20K12182
[Journal Article] Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development2021
- Author(s)
  Vogel Christoph F. A.、Lazennec Gwendal、Kado Sarah Y.、Dahlem Carla、He Yi、Castaneda Alejandro、Ishihara Yasuhiro、Vogeley Christian、Rossi Andrea、Haarmann-Stemmann Thomas、Jugan Juliann、Mori Hidetoshi、Borowsky Alexander D.、La Merrill Michele A.、Sweeney Colleen
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 625346-625346
- DOI
  10.3389/fimmu.2021.625346
- Data Source
  KAKENHI-PROJECT-20H04341
[Journal Article] DHA and Its Metabolites Have a Protective Role against Methylmercury-Induced Neurotoxicity in Mouse Primary Neuron and SH-SY5Y Cells2021
- Author(s)
  Oguro Ami、Fujita Kenta、Ishihara Yasuhiro、Yamamoto Megumi、Yamazaki Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 6 Pages: 3213-3213
- DOI
  10.3390/ijms22063213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07031, KAKENHI-PROJECT-20K12182, KAKENHI-PUBLICLY-20H05510, KAKENHI-PROJECT-19H01542, KAKENHI-PROJECT-20H04341
[Journal Article] Contribution of DHA diols (19,20-DHDP) produced by cytochrome P450s and soluble epoxide hydrolase to the beneficial effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson's disease2021
- Author(s)
  Oguro Ami、Ishihara Yasuhiro、Siswanto Ferbian Milas、Yamazaki Takeshi、Ishida Atsuhiko、Imaishi Hiromasa、Imaoka Susumu
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  
  Volume: 1866 Issue: 2 Pages: 158858-158858
- DOI
  10.1016/j.bbalip.2020.158858
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07031, KAKENHI-PROJECT-20K12182, KAKENHI-PUBLICLY-20H05510, KAKENHI-PROJECT-19H01542, KAKENHI-PROJECT-18K05357
[Journal Article] Maternal intake of docosahexaenoic acid decreased febrile seizure sensitivity by increasing estrogen synthesis in offspring2021
- Author(s)
  Kawano Shinji、Itoh Kouichi、Ishihara Yasuhiro
- Journal Title
  
  Epilepsy & Behavior
  
  Volume: 121 Pages: 108038-108038
- DOI
  10.1016/j.yebeh.2021.108038
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05510, KAKENHI-PROJECT-21K06702
[Journal Article] Measurement of the Estradiol Concentration in Cerebrospinal Fluid from Infants and Its Correlation with Serum Estradiol and Exosomal MicroRNA-126-5p2020
- Author(s)
  Ishii Masahiro、Senju Ayako、Oguro Ami、Shimono Masayuki、Araki Shunsuke、Kusuhara Koichi、Itoh Kouichi、Tsuji Mayumi、Ishihara Yasuhiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 12 Pages: 1966-1968
- DOI
  10.1248/bpb.b20-00549
- NAID
  130007948714
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05510
[Journal Article] Interleukin 33 expression induced by aryl hydrocarbon receptor in macrophages.2019
- Author(s)
  Ishihara Y, Haarmann-Stemmannd T, Kado NY, Vogel CFA
- Journal Title
  
  Toxicol Sci.
  
  Volume: In Press Issue: 2 Pages: 404-414
- DOI
  10.1093/toxsci/kfz114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0024, KAKENHI-PROJECT-17H04714
[Journal Article] Role of NF-kB RelB in Aryl Hydrocarbon Receptor-Mediated Ligand Specific Effects2019
- Author(s)
  Ishihara Yasuhiro、Kado Sarah Y.、Hoeper Christiane、Harel Shelly、Vogel Christoph F. A.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 11 Pages: 2652-2652
- DOI
  10.3390/ijms20112652
- NAID
  120006799371
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04714
[Journal Article] Retinoid X receptor-mediated neuroprotection via CYP19 upregulation and subsequent increases in estradiol synthesis2019
- Author(s)
  Ishihara Yasuhiro、Sakurai Hikaru、Oguro Ami、Tsuji Mayumi、Vogel Christoph F.A.、Yamazaki Takeshi
- Journal Title
  
  The Journal of Steroid Biochemistry and Molecular Biology
  
  Volume: 193 Pages: 105421-105421
- DOI
  10.1016/j.jsbmb.2019.105421
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04714, KAKENHI-PROJECT-17K00569
[Journal Article] Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine2019
- Author(s)
  Itoh Kouichi、Taniguchi Ruri、Matsuo Taira、Oguro Ami、Vogel Christoph F.A.、Yamazaki Takeshi、Ishihara Yasuhiro
- Journal Title
  
  Neuroscience Letters
  
  Volume: 708 Pages: 134363-134363
- DOI
  10.1016/j.neulet.2019.134363
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356, KAKENHI-PROJECT-17K15533
[Journal Article] Neuroprotective activation of astrocytes by methylmercury exposure in the inferior colliculus2019
- Author(s)
  Ishihara Yasuhiro、Itoh Kouichi、Oguro Ami、Chiba Yoichi、Ueno Masaki、Tsuji Mayumi、Vogel Christoph F. A.、Yamazaki Takeshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13899-13899
- DOI
  10.1038/s41598-019-50377-9
- NAID
  120006799369
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07508, KAKENHI-PROJECT-17H04714, KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356
[Journal Article] Progression of vasogenic edema induced by activated microglia under permanent middle cerebral artery occlusion.2018
- Author(s)
  Tanaka M, Ishihara Y, Mizuno S, Ishida A, Vogel CFA, Tsuji M, Yamazaki T, Itoh K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496(2) Issue: 2 Pages: 582-587
- DOI
  10.1016/j.bbrc.2018.01.094
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356, KAKENHI-PROJECT-18K05357
[Journal Article] Determination of chemical-specific IgGs in serum by an enzyme-linked immunosorbent assay with partial peptides of human serum albumin2018
- Author(s)
  Ishihara Yasuhiro、Ikeda-Ishihara Nami、Koriyama Chihaya、Kakiuchi Noriaki、Tanaka Masayuki、Vogel Christoph F.A.、Kawamoto Toshihiro、Tsuji Mayumi
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 43 Issue: 1 Pages: 25-31
- DOI
  10.2131/jts.43.25
- NAID
  130006338344
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0024
[Journal Article] Association between bisphenol A diglycidyl ether-specific IgG in serum and food sensitization in young children.2018
- Author(s)
  Tsuji M, Koriyama C, Ishihara Y, Vogel CFA, Kawamoto T.
- Journal Title
  
  Eur J Med Res.
  
  Volume: 23 Issue: 1 Pages: 1-9
- DOI
  10.1186/s40001-018-0358-1
- NAID
  120006799377
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09174, KAKENHI-PROJECT-15KK0024
[Journal Article] Suppressive effects of aryl-hydrocarbon receptor repressor on adipocyte differentiation in 3T3-L1 cells2018
- Author(s)
  Ishihara Yasuhiro、Tsuji Mayumi、Vogel Christoph F.A.
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 642 Pages: 75-80
- DOI
  10.1016/j.abb.2018.01.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0024
[Journal Article] Potentiation of 17β-estradiol synthesis in the brain and elongation of seizure latency through dietary supplementation with docosahexaenoic acid.2017
- Author(s)
  Ishihara Y, Itoh K, Tanaka M, Tsuji M, Kawamoto T, Kawato S, Vogel CFA, Yamazaki T
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1): Issue: 1 Pages: 6268-6268
- DOI
  10.1038/s41598-017-06630-0
- NAID
  120006782321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356
[Journal Article] Levetiracetam treatment influences blood-brain barrier failure associated with angiogenesis and inflammatory responses in the acute phase of epileptogenesis in post-status epilepticus mice2016
- Author(s)
  Kouichi Itoh, Yasuhiro Ishihara, Rie Komori, Hiromi Nochi, Ruri Taniguchi, Yoichi Chiba, Masaki Ueno, Fuyuko Takata-Tsuji, Shinya Dohgu, Yasufumi Kataoka
- Journal Title
  
  Brain Research
  
  Volume: 1652 Pages: 1-13
- DOI
  10.1016/j.brainres.2016.09.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460139, KAKENHI-PROJECT-15K08122, KAKENHI-PROJECT-15K18947
[Journal Article] Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) interacts with neurofilament L and inhibits its filament association.2016
- Author(s)
  Ozaki H, Katoh T, Nakagawa R, Ishihara Y, Sueyoshi N, Kameshita I, Taniguchi T, Hirano T, Yamazaki T, Ishida A
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 477 Issue: 4 Pages: 820-825
- DOI
  10.1016/j.bbrc.2016.06.141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842
[Journal Article] Involvement of reactive oxygen species derived from mitochondria in neuronal injury elicited by methylmercury2016
- Author(s)
  Ishihara Y, Tsuji T, Kawamoto T, Yamazaki T.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 59 Issue: 3 Pages: 182-190
- DOI
  10.3164/jcbn.16-19
- NAID
  130005268734
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340064, KAKENHI-PROJECT-15KK0024
[Journal Article] Transcription factor activation in rat primary astrocytes exposed to methylmercury.2016
- Author(s)
  Takemoto T, Ishihara Y, Tsuji M, Kawamoto T, Yamazaki T.
- Journal Title
  
  Fundam. Toxicol. Sci.
  
  Volume: 3 Pages: 63-65
- NAID
  130005133715
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26740024
[Journal Article] Prevention of status epilepticus-induced brain edema and neuronal cell loss by repeatedtreatment with high-dose levetiracetam2015
- Author(s)
  ・Itoh, K., Inamine, M., Oshima, W., Kotani, M., Chiba, Y., Ueno, M., Ishihara, Y
- Journal Title
  
  Brain Reasaech
  
  Volume: 1608 Pages: 225-234
- DOI
  10.1016/j.brainres.2015.03.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460139
[Journal Article] Prevention of status epilepticus-induced brain edema and neuronal cell loss by repeated treatment with high-dose levetiracetam.2015
- Author(s)
  Itoh K, Inamine M, Oshima W, Kotani M, Chiba Y, Ueno M, Ishihara Y.
- Journal Title
  
  Brain Res.
  
  Volume: 1608 Pages: 225-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26740024
[Journal Article] Protective actions of 17β-estradiol and progesterone on oxidative neuronal injury induced by organometallic compounds (Review Article).2015
- Author(s)
  Ishihara Y, Takemoto T, Ishida A, Yamazaki T.
- Journal Title
  
  Oxid. Med. Cell. Longev.
  
  Volume: 343706 Pages: 1-16
- DOI
  10.1155/2015/343706
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-26740024
[Journal Article] Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methylmercury.2015
- Author(s)
  Takemoto T, Ishihara Y, Ishida A, Yamazaki T.
- Journal Title
  
  Environ. Toxicol. Pharmacol.
  
  Volume: 40 Issue: 1 Pages: 199-205
- DOI
  10.1016/j.etap.2015.06.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-26740024
[Journal Article] Dual role of SOD2 induced in activated microglia: increased tolerance to oxidative stress and convergence of inflammatory responses.2015
- Author(s)
  Ishihara Y, Takemoto T, Itoh K, Ishida A, Yamazaki T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 37 Pages: 22805-22817
- DOI
  10.1074/jbc.m115.659151
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-26740024
[Journal Article] Selective estrogen-receptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway.2015
- Author(s)
  Ishihara Y, Itoh K, Ishida A, Yamazaki T.
- Journal Title
  
  J Steroid Biochem Mol Biol.
  
  Volume: 145 Pages: 85-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26740024
[Journal Article] Suppressive effects of 17β-estradiol on tributyltin-induced neuronal injury via Akt activation and attenuation of oxidative stress in rat hippocampal slices.2014
- Author(s)
  Ishihara Y, Fujitani N, Kawami T, Adachi C, Ishida A, Yamazaki T.
- Journal Title
  
  Life Sci.
  
  Volume: 99 Pages: 24-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26740024
[Journal Article] Glycolytic gene as the targets of nuclear receptor Ad4BP/SF-12014
- Author(s)
  Takashi Baba, Hiroyuki Otake, Tetsuya Sato, Kanako Miyabayashi, Yurina Shishido, Chia-Yih Wang, Yuichi Shima, Hiroshi Kimura, Mikako Yagi, Yasuhiro Ishihara, Shinjiro Hino, Hidesato Ogawa, Mitsuyoshi Nakao, Takeshi Yamazaki, Dongchon, Kang, Yasuyuki Ohkawa, Mikita Suyama, Bon-Chu Chung, Ken-ichirou Morohashi
- Journal Title
  
  Nature Commun
  
  Volume: 5 Issue: 1 Pages: 3634-3634
- DOI
  10.1038/ncomms4634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132002, KAKENHI-PLANNED-22132005, KAKENHI-PLANNED-23116009, KAKENHI-PROJECT-23590339, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26440015, KAKENHI-PROJECT-26670145, KAKENHI-PROJECT-26860194
[Journal Article] Suppressive effects of 17β-estradiol on tributyltin-induced neuronal injury via Akt activation and attenuation of oxidative stress in rat hippocampal slices.2014
- Author(s)
  Ishihara Y, Fujitani N, Kawami T, Adachi C, Ishida A, Yamazaki T.
- Journal Title
  
  Life Sci.
  
  Volume: 99 Issue: 1-2 Pages: 24-30
- DOI
  10.1016/j.lfs.2014.01.061
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25340047
[Journal Article] Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.2014
- Author(s)
  Baba T, Otake H, Sato T, Miyabayashi K, Shishido Y, Wang CY, Shima Y, Kimura H, Yagi M, Ishihara Y, Hino S, Ogawa H, Nakao M, Yamazaki T, Kang D, Ohkawa Y, Suyama M, Chung BC, Morohashi K.
- Journal Title
  
  Nat. Commun.
  
  Volume: 5 Pages: 3634-3634
- NAID
  130005085557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26740024
[Journal Article] Selective estrogen-receptor modulators suppress microglial activation2014
- Author(s)
  Yasuhiro Ishihara,, Kouichi Itoh, Atsuhiko Ishida, Takeshi Yamazaki
- Journal Title
  
  Journal of Steroid Biochemistry & Molecular Biology
  
  Volume: 145 Pages: 85-93
- DOI
  10.1016/j.jsbmb.2014.10.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340047
[Journal Article] Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices.2013
- Author(s)
  Ishihara Y, Kawami T, Ishida A, Yamazaki T.
- Journal Title
  
  J Steroid Biochem Mol Biol
  
  Volume: 135 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Involvement of brain oxidation in the cognitive impairment in a triple transgenic mouse model of Alzheimer's disease: Non-invasive measurement of the brain redox state by magnetic resonance imaging.2013
- Author(s)
  Ishihara Y, Itoh K, Mitsuda Y, Shimada T, Kubota T, Kato C, Song SY, Kobayashi Y, Mori-Yasumoto K, Sekita S, Kirino Y, Yamazaki T, Shimamoto N.
- Journal Title
  
  Free Radic Res.
  
  Volume: 47 Issue: 9 Pages: 731-739
- DOI
  10.3109/10715762.2013.818218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25870985
[Journal Article] De novosynthesized estradiol protects against methylmercury-induced neurotoxicity in cultured rat hippocampal slices2013
- Author(s)
  Yamazaki T, Yamamoto M, Ishihara Y, Onizaki M, Komatsu S, Munetsuna E, Ishida A, Kawato S, Mukuda T.
- Journal Title
  
  Pros One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] De novo synthesized estradiol protects against methylmercury-induced neurotoxicity in cultured rat hippocampal slices.2013
- Author(s)
  Yamazaki T, Yamamoto M, Ishihara Y, Onizaki M, Komatsu S, Munetsuna E, Ishida A, Kawato S, Mukuda T.
- Journal Title
  
  Pros One.
  
  Volume: 8 Issue: 4
- DOI
  10.1371/annotation/52376e1c-1a2d-44af-a129-849345da78a0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340047
[Journal Article] Pentylentetrazole-induced loss of blood-brain barrier integrity involves excess nitric oxide generation by neuronal nitric oxide synthase.2013
- Author(s)
  Danjo S, Ishihara Y, Watanabe M, Nakamura Y, Itoh K.
- Journal Title
  
  Brain Res
  
  Volume: 12 Pages: 44-53
- DOI
  10.1016/j.brainres.2013.06.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591717, KAKENHI-PROJECT-25340047
[Journal Article] Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices.2013
- Author(s)
  Yasuhiro Ishihara
- Journal Title
  
  J Steroid Biochem Mol Biol.
  
  Volume: 135 Pages: 1-6
- DOI
  10.1016/j.jsbmb.2012.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041, KAKENHI-PROJECT-25340047
[Journal Article] An active C-terminally truncated form of Ca2+/calmodulin-dependent protein kinase phosphatase-N (CaMKP-N/PPM1E).2013
- Author(s)
  Ishida A, Tsumura K, Oue M, Takenaka Y, Shigeri Y, Goshima N, Ishihara Y, Hirano T, Baba H, Sueyoshi N, Kameshita I, Yamazaki T.
- Journal Title
  
  BioMed Res. Int.
  
  Volume: 2013 Pages: 134813-134813
- DOI
  10.1155/2013/134813
- NAID
  120006557539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25460299, KAKENHI-PROJECT-25850244
[Journal Article] Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging2013
- Author(s)
  Fujii H, Sato-Akaba H, Emoto M, Itoh K, Ishihara Y, Hirata H
- Journal Title
  
  Magn Reson Imaging
  
  Volume: 31 Pages: 130-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging.2013
- Author(s)
  Hirotada Fujii
- Journal Title
  
  Magnetic Resonance Imaging
  
  Volume: 31 Issue: 1 Pages: 130-138
- DOI
  10.1016/j.mri.2012.06.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390236, KAKENHI-PROJECT-23659592, KAKENHI-PROJECT-24791318, KAKENHI-PROJECT-25340047
[Journal Article] equally contributed. Effects of sulfaphenazole after collagenase-induced experimental intra- cerebral hemorrhage in rats.2012
- Author(s)
  Hama S*, Ishihara Y*, Watanabe M, Danjo S, Nakamura Y, Itoh K. *
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35 Pages: 1849-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Sulfaphena- zole attenuates myocardial apoptosis accompanied with ischemia-reperfusion by suppressing the expression of BimEL and Noxa.2012
- Author(s)
  Ishihara Y, Shimamoto N
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 119 Pages: 251-259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione S-transferase in rat organotypic hippocampal slice cultures2012
- Author(s)
  Ishihara Y, Kawami T, Ishida A, Yamazaki T
- Journal Title
  
  Neurochem Int
  
  Volume: 60 Pages: 782-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Accumulation of cytochrome P450 induced by proteasome inhibition during cardiac ischemia2012
- Author(s)
  Ishihara Y, Hamaguchi A, Sekine M, Hirakawa A, Shimamoto N
- Journal Title
  
  Arch Biochem Biophy
  
  Volume: 527 Pages: 16-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione S-transferase in rat organotypic hippocampal slice cultures.2012
- Author(s)
  Yasuhiro Ishihara
- Journal Title
  
  Neurochem Int
  
  Volume: 60(8): Issue: 8 Pages: 782-90
- DOI
  10.1016/j.neuint.2012.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] A sensitive method based on fluorescence-detected circular dichroism for protein local structure analysis2012
- Author(s)
  Nehira T, Ishihara K, Matsuo K, Izumi S, Yamazaki T, Ishida A
- Journal Title
  
  Anal Biochem
  
  Volume: 430 Pages: 179-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Contribution of reductase activity to quinone toxicity in three kinds of hepatic cells2012
- Author(s)
  Ishihara Y, Tsuji K, Ishii S, Kashiwagi K, Shimamoto N.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35 Pages: 634-8
- NAID
  130001872217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Dual regulation of hepatocyte apoptosis by reactive oxygen species: increases in transcriptional expression and decreases in proteasomal degradation of BimEL2011
- Author(s)
  Ishihara Y, Takeuchi K, Ito F, Shimamoto N.
- Journal Title
  
  J Cell Physiol
  
  Volume: 226 Pages: 1007-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Antioxidant properties of rare sugar D-allose: Effects on mitochondrial reactive oxygen species production in Neuro2A cells2011
- Author(s)
  Ishihara Y, Katayama K, Sakabe M, Kitamura M, Aizawa M, Takara M, Itoh K
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 122 Pages: 638-642
- NAID
  110008897343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Increased expression of c-fos by ERK activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis2011
- Author(s)
  Ishihara Y, Ito F, Shimamoto N
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 1873-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.2011
- Author(s)
  Ishihara Y, Ishii S, Sakai Y, Yamamura N, Onishi Y, Shimamoto N
- Journal Title
  
  J Applied Toxicol
  
  Volume: 31 Pages: 173-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041
[Journal Article] Suppression of Myocardial Ischemia-Reperfusion Injury by Inhibitors of Cytochrome P450 in Rats.2009
- Author(s)
  Yasuhiro Ishihara
- Journal Title
  
  Eur. J. Pharmacol. (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890257
[Journal Article] Suppression of Myocardial Ischemia.Reperfusion Injury by Inhibitors of Cytochrome P450 in Rats2009
- Author(s)
  Ishihara Y., Sekine M., Nakazawa M. and Shimamoto N.
- Journal Title
  
  Eur. J. Pharmacol. (In Press)
  
  Pages: 0-0
- Data Source
  KAKENHI-PROJECT-19890257
[Journal Article] Sustained Contraction and Endothelial Dysfunction Induced by Reactive Oxygen Species in Porcine Coronary Artery2008
- Author(s)
  Ishihara Y., Sekine M., Hatano A. and Shimamoto N.
- Journal Title
  
  Biol. Pharm. Bull. 31(9)
  
  Pages: 1667-1672
- NAID
  110006878949
- Data Source
  KAKENHI-PROJECT-19890257
[Journal Article] Sustained Contraction and Endothelial Dysfunction Induced by Reactive Oxygen Species in Porcine Coronary Artery.2008
- Author(s)
  Yasuhiro Ishihara
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 1667-1672
- NAID
  110006878949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] 発達期化学物質曝露によるミクログリア活性化と異常神経回路網の形成2023
- Author(s)
  石原康宏
- Organizer
  第50回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] Impact of particulate matter 2.5 on skin condition - Using a novel air-liquid interface exposure system -2023
- Author(s)
  Maori KONO, Masayuki TAKAISHI, Kazuhiko KINOSHITA ,Hidefumi IKEDA ,Tomoaki OKUDA ,Yuri OKANO ,Yasuhiro ISHIHRA
- Organizer
  IFSCC 2023 Congress Barcelon
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11436
[Presentation] 胎児期メチル水銀暴露による神経毒性にDHA及びその代謝物が及ぼす作用解析2022
- Author(s)
  大黒亜美石原康宏山崎岳
- Organizer
  令和3年度メチル水銀研究ミーティング
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] ドコサヘキサエン酸(DHA)及びその代謝物によるメチル水銀毒性軽減作用の解明2022
- Author(s)
  大黒亜美　石原康宏　山崎岳
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] 酸化ストレスによるミクログリア炎症反応の制御2022
- Author(s)
  石原康宏
- Organizer
  第75日本酸化ストレス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] 胎児期メチル水銀暴露による神経毒性にDHA摂取がもたらす神経保護効果の検討2022
- Author(s)
  大黒亜美，石原康宏，古武弥一郎，山﨑岳
- Organizer
  フォーラム2022：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] ネオニコチノイド発達期曝露は発達期ミクログリアの急激な増殖を抑制し、興奮‐抑制バランスを興奮側にシフトする2022
- Author(s)
  難波楓、富永貴志、石原康宏
- Organizer
  第142回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] 熱性けいれん後てんかんマウスの作製とドコサヘキサエン酸(DHA)によるてんかん発症の予防2022
- Author(s)
  川野真慈、石原康宏、伊藤康一
- Organizer
  てんかん学会・第16回中四国支部会
- Data Source
  KAKENHI-PROJECT-21K06702
[Presentation] DHA代謝物によるパーキンソン病症状の軽減効果の検討2021
- Author(s)
  大黒亜美、石原康宏、今岡進、山﨑岳
- Organizer
  第94回　日本生化学大会
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] ドコサヘキサエン酸(DHA)摂取によるロテノン誘発性パーキンソン病様症状の軽減効果におけるDHA代謝物の作用解析2021
- Author(s)
  大黒亜美　石原康宏　今岡進　山崎岳
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] DHA代謝物によるロテノン誘導性パーキンソン病様症状抑制作用の検討2021
- Author(s)
  大黒　亜美、石原康宏、山﨑　岳
- Organizer
  フォーラム2021：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] マンガン過剰摂取による神経症状と脳内エストロゲンの関連.2021
- Author(s)
  石原康宏、大黒亜美、伊藤康一.
- Organizer
  フォーラム2021：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-20H05510
[Presentation] 化学物質曝露によるミクログリア活性化と異常神経回路網の形成2021
- Author(s)
  石原康宏
- Organizer
  第94 回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] ドコサヘキサエン酸(DHA)代謝物のメチル水銀毒性に対する神経細胞保護作用の検討2021
- Author(s)
  大黒亜美　藤田健太　石原康宏　山元恵　山﨑岳
- Organizer
  環境省「重金属等による健康影響に関する総合的研究」メチル水銀研究ミーティング
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] メチル水銀毒性軽減におけるドコサヘキサエン酸及びその代謝物の作用解明2021
- Author(s)
  大黒　亜美，藤田　健太，石原　康宏、山元　恵、山﨑　岳
- Organizer
  メタルバイオサイエンス研究会2021
- Invited
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] Role of DHA metabolites in protective effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson’s disease.2020
- Author(s)
  Oguro A. and Ishihara Y.
- Organizer
  1st International Electronic Conference on Biomolecules: Natural and Bio-Inspired Therapeutics for Human Diseases.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] 多価不飽和脂肪酸による神経毒に対する培養神経細胞の保護効果とその分子機構2020
- Author(s)
  藤田健太、石原康宏、大黒亜美、山﨑岳
- Organizer
  第61回　日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] Role of DHA metabolites in protective effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson’s disease.2020
- Author(s)
  Oguro A, Ishihara Y.
- Organizer
  1st International Electronic Conference on Biomolecules: Natural and Bio-Inspired Therapeutics for Human Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05510
[Presentation] ネオニコチノイド胎児期曝露による成長後の行動異常.2020
- Author(s)
  難波楓、本田達也、石原康宏.
- Organizer
  第61回生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] Activation of microglia and excitation-inhibition imbalances in the developing hippocampus of mice prenatally treated with valproate.2020
- Author(s)
  Ishihara Y, Itoh K, Tominaga T.
- Organizer
  GLIA IN HEALTH & DISEASE Cold Spring Harbor Laboratory Meetings & Courses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04341
[Presentation] てんかん原性初期における遺伝子発現変動の網羅的解析2020
- Author(s)
  小森理絵、河野智海、小澤千尋、松尾平、石原康宏、伊藤康一
- Organizer
  日本薬学会140年会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] ドコサヘキサエン酸(DHA)生体内代謝物のパーキンソン病における作用解析2020
- Author(s)
  大黒　亜美、石原康宏、山崎岳、今岡　進
- Organizer
  第61回　日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-20K07031
[Presentation] 重積発作後の脳内サイトカインストームと抗てんかん薬2019
- Author(s)
  伊藤康一、松尾　平、石原康宏
- Organizer
  第13回日本てんかん学会中国・四国地方会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 発達期の化学物質曝露によるミクログリア活性化と成長後の行動異常2019
- Author(s)
  石原康宏
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] Developmental microglial activation and postgrowth abnormal behavior induced by prenatal exposure of chemicals2019
- Author(s)
  Ishihara Y
- Organizer
  The 35th Annual Meeting of KSOT/KEMS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] てんかん原性初期の脳内変化とてんかん発症に対する五苓散の効果2019
- Author(s)
  小森理絵、大江優美、石原康宏、松尾平、伊藤康一
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] てんかん原性初期における脳内炎症関連サイトカインのプロファイル2018
- Author(s)
  伊藤　康一、橋本律香、久保静香、松尾平、小森理絵、水野翔童、石原康宏
- Organizer
  日本薬学会第138 年会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 脳虚血時に生じる芳香族炭化水素受容体を介した酸化的神経障害.2018
- Author(s)
  石原康宏、田中美樹、伊藤康一、山崎岳、Christoph FA Vogel.
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] 芳香族炭化水素受容体によるインターロイキン33の発現誘導2018
- Author(s)
  石原康宏、Christoph F. A. Vogel.
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] 芳香族炭化水素受容体によるインターロイキン33の発現誘導.2018
- Author(s)
  石原康宏、Christoph F. A. Vogel.
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] Aryl-hydrocarbon Receptor Repressorによる脂肪細胞分化抑制作用.2018
- Author(s)
  石原康宏、Christoph F. A. Vogel.
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] 芳香族炭化水素受容体によるp47phox発現亢進と酸化ストレスの誘導.2018
- Author(s)
  石原康宏、山﨑岳、Christoph Vogel.
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] マクロファージにおける芳香族炭化水素受容体を介したインターロイキン33の発現上昇.2018
- Author(s)
  石原康宏、Christoph F. A. Vogel.
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] てんかん原性形成における免疫細胞動態－サイトカインストームとの関連性－2018
- Author(s)
  伊藤康一、石原康宏
- Organizer
  生体機能と創薬シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] Effects of valproate prenatal exposure on developmental microglial activity and neural circuit formation2018
- Author(s)
  Y. ISHIHARA, T. HONDA, R. TANIGUCHI, N. ISHIHARA, T. YAMAZAKI
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] The plural chemical specific- IgG values of two small plants' workers handling plastic resins.2018
- Author(s)
  辻真弓、石原康宏、石原波、田中里枝、一瀬豊日、川本俊弘
- Organizer
  Society of Toxicology 57th Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09174
[Presentation] 自閉症モデルマウスにおけるミクログリアの過剰な活性化とシナプスの減少.2017
- Author(s)
  本田達也、石原康宏、石田敦彦、山崎岳.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] Activation of microglia and loss of synapse in the developing hippocampus of mice prenatally treated by valproate.2017
- Author(s)
  Honda T, Ishihara Y, Ishida A, Yamazaki T.
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] 症候性てんかん原性脳内における炎症関連分子発現プロファイリング2017
- Author(s)
  伊藤　康一、橋本律香、久保静香、松尾平、小森理絵、水野翔童、石原康宏
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 自閉症モデルマウスにおける脳発達期のミクログリアの過剰な貪食.2017
- Author(s)
  本田達也、石原康宏、石田敦彦、山崎岳.
- Organizer
  第58回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-17H04714
[Presentation] ニューロステロイド合成と神経保護作用のレチノイドX受容体アゴニストによる亢進2016
- Author(s)
  櫻井　光、石原康宏、石田敦彦、山﨑　岳
- Organizer
  第23回ステロイドホルモン学会学術集会
- Place of Presentation
  倉敷市
- Year and Date
  2016-01-15
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) interacts with neurofilament L and inhibits its filament association2016
- Author(s)
  Hana Ozaki, Tsuyoshi Katoh, Ryoko Nakagawa, Yasuhiro Ishihara, Noriyuki Sueyoshi, Isamu Kameshita, Takanobu Taniguchi, Tetsuo Hirano, Takeshi Yamazaki, Atsuhiko Ishida
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東大阪市・近畿大学
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K01824
[Presentation] メチル水銀によるアストロサイト適応応答とその神経保護作用.2016
- Author(s)
  石原康宏、竹本拓矢、山﨑岳.
- Organizer
  平成26年度環境省「重金属等による健康影響に関する総合的研究」メチル水銀研究ミーティング.
- Place of Presentation
  東京
- Year and Date
  2016-01-07
- Data Source
  KAKENHI-PROJECT-26740024
[Presentation] Role of astrogliosis elicited by methylmercury in neuroprotection.2016
- Author(s)
  Yasuhiro Ishihara
- Organizer
  Prenatal Programming and Toxicity V.
- Place of Presentation
  Kitakyushu International Conference Center（福岡県・北九州市）
- Year and Date
  2016-11-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0024
[Presentation] Neuroprotection by de novo synthesized estradiol and brain converted allopregnanolone in cultured rat hippocampus2016
- Author(s)
  Yamazaki T. , Ishihara Y. , Yamamoto M.
- Organizer
  8th International Meeting 　STEROIDS and NERVOUS SYSTEM
- Place of Presentation
  TORINO Ｉｔａｌｙ
- Year and Date
  2016-02-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] 脳のステロイドを人為的に増減する2015
- Author(s)
  櫻井　光、石原康宏、山﨑　岳
- Organizer
  内外環境応答・代謝酵素研究会
- Place of Presentation
  旭川市
- Year and Date
  2015-07-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] メチル水銀により生じる聴覚伝導路異常の解析.2015
- Author(s)
  石原康宏、伊藤康一、高橋亮平、石田敦彦、山崎岳.
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26740024
[Presentation] メチル水銀による酸化ストレス誘導メカニズムの解明とそのin vivo神経影響評価.2015
- Author(s)
  石原康宏
- Organizer
  第34回生体と金属・化学物質に関する研究会
- Place of Presentation
  滋賀
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26740024
[Presentation] De novo synthesis and conversion of neuroprotective steroids2015
- Author(s)
  Takeshi Yamazaki, Yasuhiro Ishihara
- Organizer
  19th International Conference on Cytochrome P450
- Place of Presentation
  東京
- Year and Date
  2015-06-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] CaMキナーゼホスファターゼはニューロフィラメント Lと結合して重合を阻害する2015
- Author(s)
  尾崎華 , 加藤剛志 , 中川綾.子 , .石原康宏 , 末吉紀.行. , .亀下勇 , .谷.口隆信 , .山崎岳 , .石.田敦彦
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  松江市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K01824
[Presentation] 蛍光検出円二色性(FDCD)分光法が可能にするタンパク質立体構造変化の検出2015
- Author(s)
  伊藤弘音、根平達夫、石原郁、益田恵子、浮穴和義、松尾光一、泉俊輔、山﨑岳、石田敦彦
- Organizer
  第５６回日本生化学会中国・四国支部例会
- Place of Presentation
  神戸市
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K01824
[Presentation] Protein conformational analysis by fluorescence-detected circular dichroism (FDCD)2015
- Author(s)
  Tatsuo Nehira, Kaoru Ishihara, Hirone Ito, Keiko Masuda, Kazuyoshi Ukena, Koichi Matsuo, Shunsuke Izumi, Takeshi Yamazaki, and Atsuhiko Ishida
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01824
[Presentation] 孤独環境はラット海馬のBDNF量を低下させトリメチルスズによる神経毒性を増加させた2015
- Author(s)
  山崎岳、石原康宏、大山勤、椋田崇生、小山友香、石田敦彦
- Organizer
  第３８回日本神経科学大会
- Place of Presentation
  神戸市
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] Status epileptics後に出現する脳浮腫に対する五苓散の効果2015
- Author(s)
  伊藤　康一、大江　優美、小森　理絵、石原　康宏
- Organizer
  香川脳神経研究会（第10回定例会）
- Place of Presentation
  ロイヤルパークホテル高松
- Year and Date
  2015-01-16
- Data Source
  KAKENHI-PROJECT-26460139
[Presentation] レチノイドX受容体アゴニストによる2015
- Author(s)
  櫻井　光、石原康宏、石田敦彦、山﨑　岳
- Organizer
  第127 回日本薬理学会近畿部会
- Place of Presentation
  岐阜市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] メチル水銀の聴覚伝導路への影響.2014
- Author(s)
  石原康宏、伊藤康一、高橋亮平、山崎岳.
- Organizer
  平成26年度メチル水銀研究ミーティング
- Place of Presentation
  LMJ東京研修センター
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-26740024
[Presentation] A physiological role of Mn-SOD induced by inflammatory stimuli in microglial cells.2014
- Author(s)
  Yasuhiro Ishihara, Atsuhiko Ishida, Takeshi Yamazaki
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] ニューロステロイドによる神経保護作用2013
- Author(s)
  山崎　岳、石原　康宏、冨士谷　法子
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] Neuronal injury and oxidative stress induced by tributyltin in rat hippocampal cultured slices2013
- Author(s)
  Yamazaki Takeshi1, Ishihara Yasuhiro1, Kawami Tomohito1, Ishida Atsuhiko1
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] 性ステロイドホルモンによる神経保護作用―虚血再還流モデル系―2013
- Author(s)
  冨士谷法子　石原康宏　石田敦彦　山崎岳
- Organizer
  第21回日本ステロイドホルモン学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] トリブチルスズによる酸化的神経障害とステロイドホルモンの神経保護作用2013
- Author(s)
  石原康宏、山崎岳
- Organizer
  メタルバイオサイエンス研究会
- Place of Presentation
  静岡市
- Invited
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] トリブチルスズより引き起こされる海馬神経障害の機序2012
- Author(s)
  石原　康宏
- Organizer
  日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] トリブチルスズにより引き起こされる海馬神経障害の機序2012
- Author(s)
  石原康宏
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] チトクロムP450阻害によるキノン肝毒性の亢進2012
- Author(s)
  石原康宏
- Organizer
  第51回日本薬学会中国四国支部学術大会
- Place of Presentation
  松江 (奨励賞受賞講演)
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] アルツハイマー症モデルマウスにおける脳内酸化還元状態と認知機能の相関2012
- Author(s)
  石原康宏
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] アルツハイマー病モデルマウスにおける脳内酸化還元状態と認知機能との相関2012
- Author(s)
  石原康宏
- Organizer
  酸化ストレス学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] 蛍光検出円二色性(FDCD)を用いたタンパク質立体構造解析のピンポイント検出の試み2010
- Author(s)
  石原郁
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] 蛍光検出円二色性(FDCD)を用いたタンパク質立体構造解析のピンポイント検出の試み2010
- Author(s)
  石原郁、泉俊輔、石田敦彦、山崎岳、根平達夫
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22310041
[Presentation] Enhancement of quinone-induced hepatotoxicity by cytochrome P450 inhibition in rats.2009
- Author(s)
  Yasuhiro Ishihara
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] Oxygen radicals-induced contraction and endothelial damage of porcine coronary artery2008
- Author(s)
  Yasuhiro Ishihara
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] 神経毒に対するアストロサイト適応応答のメカニズム解析
- Author(s)
  竹本拓矢、石原康宏、石田　敦彦、山崎岳
- Organizer
  日本薬学会　第135年回
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] 酸化ストレスにより引き起こされる EGFR-ERK 活性化を介したアポトーシス
- Author(s)
  石原康宏、関根雅也、竹内健治、伊藤文昭、嶋本典夫
- Organizer
  第61 回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] 持続的酸化ストレスによって引き起こされるカスパーゼ非依存的肝細胞アポトーシスの機序
- Author(s)
  石原康宏、嶋本典夫
- Organizer
  第29 回日本フリーラジカル学会学術集会/日本過酸化脂質・フリーラジカル学会第31 回大会合同学会
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] Hepatocyte apoptosis induced by endogenous oxidative stress is mediated through EGFR-ERK activation
- Author(s)
  Yasuhiro Ishihara, Kenji Takeuchi, Fumiaki Ito and Norio Shimamoto
- Organizer
  第31 回日本分子生物学会年会・第81 回日本生化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] LOCALLY DERIVED ESTRADIOL IN THE PREFRONTAL CORTEX AND HIPPOCAMPUS ENHANCES MEMORY AND BLOCKS DELETERIOUS EFFECTS OF STRESS
- Author(s)
  Yamazaki T. , Ishihara Y., Yamamoto M.
- Organizer
  12th International Symposium on Cytochrome P450 P450 Biodiversity & Biotechnology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-28
- Invited
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] 神経毒に対するアストロサイトの適応応答とその神経保護作用
- Author(s)
  竹本拓矢、石原康宏、石田　敦彦、山崎岳
- Organizer
  日本薬学会　中国四国支部学術大会
- Place of Presentation
  広島市
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] てんかん原性初期に発現する脳浮腫に対する五苓散の効果
- Author(s)
  大江優美、石原康宏、小森理絵、伊藤康一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  ザイン・クリエイティブセンター神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460139
[Presentation] 有機スズによる酸化的神経障害とその内因性防御因子としてのニューロステロイド.
- Author(s)
  石原康宏.
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26740024
[Presentation] 有機スズによる酸化的神経障害とその内因性防御因子としてのニューロステロイド
- Author(s)
  石原康宏、山崎岳
- Organizer
  日本薬学会　第135年回
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] Enhancement of quinone-induced hepatotoxicity by cytochrome P450 inhibition in rats
- Author(s)
  Yasuhiro Ishihara, Satomi Ishii, Yufu Sakai and Norio Shimamoto
- Organizer
  第82 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] Oxygen radicals-induced contraction and endothelial damage of porcine coronary artery
- Author(s)
  Yasuhiro Ishihara, Ai Hatano and Norio Shimamoto
- Organizer
  第81 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19890257
[Presentation] Protective functions of P450s in rat hippocampus
- Author(s)
  Takeshi Yamazaki, Yasuhiro Ishihara
- Organizer
  8th International Meeting 　STEROIDS and NERVOUS SYSTEM
- Place of Presentation
  TORINO, Italy
- Year and Date
  2015-02-14 – 2015-02-18
- Data Source
  KAKENHI-PROJECT-25340047
[Presentation] てんかん原性の五苓散による予防的治療効果の可能性の検討
- Author(s)
  大江優美、稲嶺盛佳、川真田実来、小森理絵、石原康宏、伊藤康一
- Organizer
  第53回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  広島国際会議場
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-26460139
[Presentation] 核磁気共鳴画像法を用いたメチル水銀投与により生じる脳内酸化と神経機能異常測定の試み.
- Author(s)
  石原康宏、伊藤康一、高橋亮平、石田敦彦、山﨑岳.
- Organizer
  フォーラム2014：衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26740024

1. Itoh Kouichi (30291149)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. 冨永貴志 (20344046)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. YAMAZAKI Takeshi (30192397)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
4. ISHIDA Atsuhiko (90212886)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
5. Oguro Ami (20634497)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
6. MUKUDA Takao (60346335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. Tsuji Mayumi (40457601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 川本俊弘 (60177748)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. SKATA Shogo (50153888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KOTAKE Yaichirou (20335649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIDE Michihiro (50284188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 根平達夫 (60321692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 荒木俊介 (20515481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 柴田英治 (90419838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 今岡進 (60145795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 大島隆幸 (10397557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 米澤智洋 (10433715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 村田幸久 (40422365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 藤井渉 (40708161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 前田真吾 (80755546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小森理絵 (70412400)

# of Collaborated Projects: 1 results

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22. Tin・Tin Win・Shwe (00391128)

# of Collaborated Projects: 1 results

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23. 石塚一枝 (00754574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中島大介 (10281411)

# of Collaborated Projects: 1 results

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25. 東賢一 (80469246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 河野まおり (60880995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. Vogel Christoph

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
28. Haarmann-Stemmann Thomas

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. BABA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 諸橋憲一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 嶋雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 中村祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 千葉陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 藤井博匡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishihara Yasuhiro 石原 康宏

ISHIHARA Yasuhiro 石原 康宏

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発達神経毒性研究の新機軸：脳内ケモカインによるミエリン形成阻害Principal Investigator

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脳スライスをジオラマ環境として用いたオリゴデンドロサイト前駆細胞の原生知能の解析Principal Investigator

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無痛分娩に伴う非感染性発熱と児の発達との関連性を解き明かす実験的アプローチPrincipal Investigator

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エストロゲンとマンガン動態との関連に着目したマンガン神経毒性性差発現機構の解明Principal Investigator

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Disruption of brain chemokine networks and impaired neural circuit formation due to developmental exposure to chemicalsPrincipal Investigator

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Formation of abnormal neural circuit elicited by microglia with modulated gene expression exposed to environmental chemicalsPrincipal Investigator

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Ishihara Yasuhiro 石原康宏

ISHIHARA Yasuhiro 石原康宏