Hanyu Masayuki 破入正行

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HANYU Masayuki 破入正行

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Researcher Number	80435552
Other IDs
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 主任研究員
Affiliation (based on the past Project Information) *help	2021 – 2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 主任研究員 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 主任研究員(任常) 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 研究員(任常) 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所標識薬剤開発部, 研究員(任常) 2016: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所標識薬剤開発部, 研究員(任常) 2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 2012 – 2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator PET / PETイメージング / 放射性金属核種 / 銅-64 / 標識反応 / オリゴペプチド / ピクテスペングラー反応 / 放射性治療核種 / 位置特異的修飾方法 / 糖鎖修飾抗体 … More / 位置特異的修飾 / 糖鎖 / 抗体 / 位置特異的標識 / 抗体標識 / PET核種 / 環状ペプチド / ナノ粒子 / 標識方法 / At-211 / Cu-64 / 標識合成 / 遠隔合成装置 … More Except Principal Investigator アルファ線放出核種 / PET / R-Senolytics / 老化細胞 / Radio-Senolytics / TRT治療 / PET診断 / mGluR1 / α線治療薬 / PET診断薬 / Radio-theranostics / 代謝型グルタミン酸受容体1型 / PET imaging / intracellular delivery / radionuclide therapy / 64Cu / cancer / intracellular protein / radiotheranostics / stapled peptide Less

糖鎖上に放射性核種をもつ診断・治療標識抗体の研究基盤の構築Principal Investigator
- Principal Investigator
  
  破入正行
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of Radio-Senolytics for Imaging and Deleting Senescent Cells
- Principal Investigator
  
  張明栄
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Institutes for Quantum Science and Technology
Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapy
- Principal Investigator
  
  胡寛
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Construction of a mGluR1-targeted radiotheranostic system for tumor-agnostic cancer treatment
- Principal Investigator
  
  Xie Lin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
キレーター含有糖ユニットで修飾した抗体の標識反応と評価Principal Investigator
- Principal Investigator
  
  破入正行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Synthesis and evaluation of radioactive nanometallic agents that specifically recognize pancreatic cancer cellsPrincipal Investigator
- Principal Investigator
  
  HANYU Masayuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institutes for Quantum Science and Technology
Radiosynthesis and evaluation of tumor cell-penetrating oligopeptides containing short-lived positron-emitt ing radionuclidesPrincipal Investigator
- Principal Investigator
  
  Hanyu Masayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Radiosynthesis and evaluation of peptide probe containing short-lived positron-emitting radionuclides via a Pictet-Spengler reactionPrincipal Investigator
- Principal Investigator
  
  HANYU Masayuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy2023
- Author(s)
  Xie Lin、Zhang Lulu、Hu Kuan、Hanyu Masayuki、Zhang Yiding、Fujinaga Masayuki、Minegishi Katsuyuki、Ohkubo Takayuki、Nagatsu Kotaro、Jiang Cuiping、Shimokawa Takashi、Ashisuke Kazuma、Okonogi Noriyuki、Yamada Shigeru、Wang Feng、Wang Rui、Zhang Ming-Rong
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 4 Pages: 100960-100960
- DOI
  10.1016/j.xcrm.2023.100960
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714, KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-23K27558
[Journal Article] Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022
- Author(s)
  Hu Kuan, Wu Wenyu, Xie Lin, Geng Hao, Zhang Yiding, Hanyu Masayuki, Zhang Lulu, Liu Yinghuan, Nagatsu Kotaro, Suzuki Hisashi, Guo Jialin, Wu Yundong, Li Zigang, Wang Feng, Zhang Ming-Rong
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 12 Issue: 3 Pages: 1363-1376
- DOI
  10.1016/j.apsb.2021.09.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
[Journal Article] Automated radiosynthesis of [11C]MTP38-a phosphodiesterase 7 imaging tracer using [11C]hydrogen cyanide for clinical applications2022
- Author(s)
  Kawamura Kazunori、Hashimoto Hiroki、Ohkubo Takayuki、Hanyu Masayuki、Ogawa Masanao、Nengaki Nobuki、Arashi Daisuke、Kurihara Yusuke、Fujishiro Tomoya、Togashi Takahiro、Sakai Toshiyuki、Muto Masatoshi、Takei Makoto、Ishii Hideki、Saijo Takeaki、Matsumura Takehiko、Obokata Naoyuki、Zhang Ming‐Rong
- Journal Title
  
  Journal of Labelled Compounds and Radiopharmaceuticals
  
  Volume: 65 Issue: 5 Pages: 140-146
- DOI
  10.1002/jlcr.3965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19H03610, KAKENHI-PROJECT-20H03635
[Journal Article] Development of a Stable Peptide-Based PET Tracer for Detecting CD133-Expressing Cancer Cells2021
- Author(s)
  Hu Kuan、Ma Xiaohui、Xie Lin、Zhang Yiding、Hanyu Masayuki、Obata Honoka、Zhang Lulu、Nagatsu Kotaro、Suzuki Hisashi、Shi Rui、Wang Weizhi、Zhang Ming-Rong
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 1 Pages: 334-341
- DOI
  10.1021/acsomega.1c04711
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
[Journal Article] Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin2021
- Author(s)
  Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Fujinaga Masayuki、Mori Wakana、Kumata Katsushi、Hanyu Masayuki、Furutsuka Kenji、Hashimoto Hiroki、Kawamura Kazunori、Zhang Ming-Rong
- Journal Title
  
  EJNMMI Radiopharmacy and Chemistry
  
  Volume: 6 Issue: 1 Pages: 23-23
- DOI
  10.1186/s41181-021-00138-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19H03610, KAKENHI-PROJECT-20H03635
[Journal Article] <sup>211</sup>At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer2021
- Author(s)
  Shi Xiumin、Li Qing、Zhang Lulu、Hanyu Masayuki、Xie Lin、Hu Kuan、Nagatsu Kotaro、Zhang Chuan、Wu Zhengcan、Wang Feng、Zhang Ming-Rong、Yang Kai、Zhu Ran
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 32 Issue: 8 Pages: 1763-1772
- DOI
  10.1021/acs.bioconjchem.1c00263
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659
[Journal Article] PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide2020
- Author(s)
  Hu Kuan、Shang Jingjie、Xie Lin、Hanyu Masayuki、Zhang Yiding、Yang Zhimin、Xu Hao、Wang Lu、Zhang Ming-Rong
- Journal Title
  
  ACS Omega
  
  Volume: 5 Issue: 15 Pages: 8508-8514
- DOI
  10.1021/acsomega.9b03953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Simple separation of 67Cu from bulk zinc by coprecipitation using hydrogen sulfide gas and silver nitrate2020
- Author(s)
  Tomoyuki Ohya, Kotaro Nagatsu, Masayuki Hanyu, Katsuyuki Minegishi, Ming-Rong Zhang
- Journal Title
  
  Radiochimica Acta
  
  Volume: - Issue: 6 Pages: 469-476
- DOI
  10.1515/ract-2019-3168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10386, KAKENHI-PROJECT-18K07281
[Journal Article] Radiosynthesis of [thiocarbonyl-11C]disulfiram and its first PET study in mice2020
- Author(s)
  Ishii Hideki、Yamasaki Tomoteru、Yui Joji、Zhang Yiding、Hanyu Masayuki、Ogawa Masanao、Nengaki Nobuki、Tsuji Atsushi B.、Terashima Yuya、Matsushima Kouji、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: - Issue: 6 Pages: 126998-126998
- DOI
  10.1016/j.bmcl.2020.126998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PLANNED-17H06392
[Journal Article] Radiosynthesis and evaluation of 4-(6-[18F]Fluoro-4-(5-isopropoxy-1H-indazol-3-yl)pyridin-2-yl)morpholine as a novel radiotracer candidate targeting leucine-rich repeat kinase 22020
- Author(s)
  Mori Wakana、Yamasaki Tomoteru、Hattori Yasushi、Zhang Yiding、Kumata Katsushi、Fujinaga Masayuki、Hanyu Masayuki、Nengaki Nobuki、Zhang Hong、Zhang Ming-Rong
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 11 Issue: 6 Pages: 676-684
- DOI
  10.1039/c9md00590k
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-20H03635
[Journal Article] Harnessing the PD-L1 interface peptide for positron emission tomography imaging of the PD-1 immune checkpoint2020
- Author(s)
  Hu Kuan、Xie Lin、Hanyu Masayuki、Zhang Yiding、Li Lingyun、Ma Xiaohui、Nagatsu Kotaro、Suzuki Hisashi、Wang Weizhi、Zhang Ming-Rong
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 1 Issue: 4 Pages: 214-224
- DOI
  10.1039/d0cb00070a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy2020
- Author(s)
  Hu Kuan、Xie Lin、Zhang Yiding、Hanyu Masayuki、Yang Zhimin、Nagatsu Kotaro、Suzuki Hisashi、Ouyang Jiang、Ji Xiaoyuan、Wei Junjie、Xu Hao、Farokhzad Omid C.、Liang Steven H.、Wang Lu、Tao Wei、Zhang Ming-Rong
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 2778-2778
- DOI
  10.1038/s41467-020-16513-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Development of a remote purification apparatus with disposable evaporator for the routine production of high-quality 64Cu for clinical use2019
- Author(s)
  Ohya Tomoyuki、Minegishi Katsuyuki、Suzuki Hisashi、Nagatsu Kotaro、Fukada Masami、Hanyu Masayuki、Zhang Ming-Rong
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 146 Pages: 127-132
- DOI
  10.1016/j.apradiso.2019.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10386, KAKENHI-PROJECT-18K07281
[Journal Article] Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation2019
- Author(s)
  Kuan Hu、Masayuki Hanyu、Xie Lin、Zhang Yiding、Kotaro Nagatsu、Hisashi Suzuki、Zhang Ming-Rong
- Journal Title
  
  Chemical Communications
  
  Volume: 55 Issue: 29 Pages: 4162-4165
- DOI
  10.1039/c9cc00445a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-17K16495
[Journal Article] 131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 12019
- Author(s)
  Xie Lin、Hanyu Masayuki、Fujinaga Masayuki、Zhang Yiding、Hu Kuan、Minegishi Katsuyuki、Jiang Cuiping、Kurosawa Fuki、Morokoshi Yukie、Li Huizi Keiko、Hasegawa Sumitaka、Nagatsu Kotaro、Zhang Ming-Rong
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 61 Issue: 2 Pages: 242-248
- DOI
  10.2967/jnumed.119.230946
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
[Journal Article] Synthesis and Evaluation of [64Cu]PSMA-617 Targeted for Prostate-Specific Membrane Antigen in Prostate Cancer2017
- Author(s)
  Can Cui, Masayuki Hanyu, Akiko Hatori, Yiding Zhang, Lin Xie, Tomoyuki Ohya, Masami Fukada, Hisashi Suzuki, Kotaro Nagatsu, Cuiping Jiang, Rui Luo, Guoqiang Shao, Ming-Rong Zhang, Feng Wang
- Journal Title
  
  American Journal of Nuclear Medicine and Molecular Imaging
  
  Volume: 7 Pages: 40-52
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861031
[Journal Article] High-contrast PET imaging of vasopressin V1B receptors with a novel radioligand, 11C-TASP6992017
- Author(s)
  Kazumi Koga, Yugi Nagai, Masayuki Hanyu, Mitsukane Yoshinaga, Shigeyuki Chaki, Norikazu Ohtake, Satoshi Ozaki, Ming-Rong Zhang, Tetsuya Suhara, Makoto HIguchi
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: - Issue: 10 Pages: 1652-1658
- DOI
  10.2967/jnumed.116.188698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861031, KAKENHI-PROJECT-16H05324
[Journal Article] Efficient preparation of high-quality 64Cu for routine use2016
- Author(s)
  Tomoyuki Ohya, Kotaro Nagatsu, Hisashi Suzuki, Masami Fukada, Katsuyuki Minegishi, Masayuki Hanyu, Toshimitsu Fukumura, Ming-Rong Zhang
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 43 Issue: 11 Pages: 685-691
- DOI
  10.1016/j.nucmedbio.2016.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861031
[Journal Article] Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors2016
- Author(s)
  Kazumi Koga, Jun Maeda, Masaki Tokunaga, Masayuki Hanyu, Kazunori Kawamura, Mari Ohmichi, Toshio Nakamura, Yuji Nagai, Chie Seki, Yasuyuki Kimura, Takafumi Minamimoto, Ming-Rong Zhang, Toshimitsu Fukumura, Tetsuya Suhara, Makoto Higuchi
- Journal Title
  
  EJNMMI Research
  
  Volume: 6 Issue: 1 Pages: 1-14
- DOI
  10.1186/s13550-016-0170-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861031, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-25460114, KAKENHI-PLANNED-15H05917
[Journal Article] Radiosynthesis and quality control of [11C]TASP457 as a clinically useful PET ligand for imaging of histamine H3 receptors in human brain2016
- Author(s)
  Masayuki Hanyu, Kazunori Kawamura, Makoto Takei, Kenji Furutsuka, Satoshi Shiomi, Tomoya Fujishiro, Masanao Ogawa, Nobuki Nengaki, Hiroki Hashimoto, Toshimitsu Fukumura, Ming-Rong Zhang
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 43 Issue: 11 Pages: 679-684
- DOI
  10.1016/j.nucmedbio.2016.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861031
[Journal Article] Preliminary PET Study of Carbon-11 Labeled RGD Peptide by Using Carbon-11 Formaldehyde2016
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Journal Title
  
  PEPTIDE SCIENCE 2015
  
  Volume: 52 Pages: 663-668
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861031
[Journal Article] Development of radiolabeling technique for cyclic RGD peptide by using carbon-11 formaldehyde2014
- Author(s)
  Masayuki Hanyu
- Journal Title
  
  NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCE, ANNUAL REPORT 2013-2014
  
  Volume: 52 Pages: 36-37
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861031
[Journal Article] Radiolabeling and Preliminary PET Study of Carbon-11 Labeled Amino Acids and Oligopeptides by Using Carbon-11 Formaldehyde2014
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Aung U Winn, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Journal Title
  
  Peptide Science 2013
  
  Volume: 50 Pages: 181-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Journal Article] Radiolabeling and Preliminary PET Study of Carbon-11 Labeled Amino Acids and Oligopeptides by Using Carbon-11 Formaldehyde; Peptide Science 2013, Y. Nishiuchi and T. Teshima (Ed.)2014
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Aung U Winn, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Journal Title
  
  The Japanese Peptide Society
  
  Pages: 181-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Journal Article] Radiolabeling of Oligopeptides Containing [1-11C]-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid via a Pictet-Spengler Reaction2013
- Author(s)
  Masayuki Hanyu
- Journal Title
  
  PEPTIDE SCIENCE 2012
  
  Volume: 49 Pages: 303-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Journal Article] Carbon-11 radiolabeling of an oligopeptide containing tryptophan hydrochloride via a Pictet-Spengler reaction using carbon-11 formaldehyde2013
- Author(s)
  Masayuki Hanyu, Yuuki Takada, Hiroki Hashimoto, Kazunori Kawamura, Ming-Rong Zhang, Toshimitsu Fukumura
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 19(10) Pages: 663-668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Journal Article] Radiolabeling of oligopeptides containing [1-<11>^C]-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxyl ic acid via a Pictet-Spengler reaction; Peptide Science 2012, K. Sugimura (Ed.)2013
- Author(s)
  Masayuki Hanyu, Yuuki Takada, Hiroki Hashimoto, Kazunori Kawamura, Ming-Rong Zhang, Toshimitsu Fukumura
- Journal Title
  
  The Japanese Peptide Society
  
  Pages: 303-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Journal Article] Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE2012
- Author(s)
  Yuuki Takada, Masayuki Hanyu, Koutarou Nagatsu, Toshimitsu Fukumura
- Journal Title
  
  Journal of Labeled Compounds & Radiopharmaceuticals
  
  Volume: 55(10) Pages: 383-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] Targeted alpha Therapy with 211At-AITM for mGluR1 positive human cancers2024
- Author(s)
  Xie Lin, Hanyu Masayuki, Yiding Zhang, Lulu Zhang, Fujinaga Masayuki, Minegishi Katsuyuki, Takayuki Ohkubo, Nagatsu Kotaro, Zhang Ming-Rong
- Organizer
  The 11th Takeda Science Foundation Symposium on PhamaSciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] mGluR1陽性ヒト癌に対する211At-AITMによる標的アイソトープ治療の検証2023
- Author(s)
  謝琳, 破入正行, 張一鼎, 藤永雅之, 峯岸克行, 大久保崇之, 永津弘太郎, 下川卓志, 足助一真, 張明栄
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] 211At-AITM RPT: a tumor agnostic therapeutic strategy for mGluR1 positive human cancers2023
- Author(s)
  ie Lin, Hanyu Masayuki, Yiding Zhang, Lulu Zhang, Fujinaga Masayuki, Minegishi Katsuyuki, Takayuki Ohkubo, Nagatsu Kotaro, Zhang Ming-Rong
- Organizer
  SNMMI2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Synthesis and evaluation of At-211 labeled TRT-radiopharmaceuticals (At-AITM) for melanoma with overexpressed metabotropic glutamate receptor 12022
- Author(s)
  Hanyu Masayuki, Xie Lin, Yiding Zhang, Minegishi Katsuyuki, Kadoma Ayumi, Hu Kuan, Fujinaga Masayuki, Nagatsu Kotaro, Ishioka Noriko, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07714
[Presentation] TRT薬剤211At-AITM誘導体の合成と評価2022
- Author(s)
  破入　正行, 謝　琳, 張　一鼎, 峯岸　克行, 門間　あゆみ, Hu　Kuan, 藤永　雅之, 永津　弘太郎, 石岡　典子, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Development of metabotropic glutamate receptor 1-targeted radiopharmaceuticals for theranostics of melanoma2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] TRT薬剤211At-AITM　誘導体の合成と評価2022
- Author(s)
  破入　正行, 謝　琳, 張　一鼎, 峯岸　克行, 門間　あゆみ, Hu　Kuan, 藤永　雅之, 永津　弘太郎, 石岡　典子, 張　明栄
- Organizer
  第62会日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07714
[Presentation] Synthesis and evaluation of At-211 labeled TRT-radiopharmaceuticals (At-AITM) for melanoma with overexpressed metabotropic glutamate receptor 1.2022
- Author(s)
  Hanyu Masayuki, Xie Lin, Yiding Zhang, Minegishi Katsuyuki, Kadoma Ayumi, Hu Kuan, Fujinaga Masayuki, Nagatsu Kotaro, Ishioka Noriko, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] 癌蛋白質mGluR1に基づくラジオセラノスティクス薬剤の開発2022
- Author(s)
  謝　琳, 破入　正行, 藤永　雅之, 張　一鼎, 張露露, 森　若菜, Hu　Kuan, 峯岸　克行, 永津　弘太郎, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Theranostics of melanoma targeting metabotropic glutamate receptor 1 with a novel small-molecular radiopharmaceutical pair2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Kawamura Kazunori, Zhang Ming-Rong
- Organizer
  SNMMI2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] 糖鎖加水分解パニツムマブの標識合成と体内動態2022
- Author(s)
  破入　正行, 謝　琳, 張　一鼎, 森　昌子, 筒井　正斗, 水野　真盛, 張　明栄
- Organizer
  第1回　日本抗体学会設立記念学術大会
- Data Source
  KAKENHI-PROJECT-21K07714
[Presentation] Development of a stable peptide-based PET tracer for detecting CD133-expressing cancer stem cells2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Obata Honoka , Nagatsu Kotaro , Suzuki Hisashi , Zhang Ming-Rong
- Organizer
  第4回日本核医学会分科会放射線薬品科学研究会第20回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021
- Author(s)
  Hu　Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong:
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] TRT薬剤「211At-AITM」合成法の改良2021
- Author(s)
  破入　正行, 峯岸　克行, 門間　あゆみ, 謝　琳, Hu　Kuan, 張　一鼎, 藤永　雅之, 永津　弘太郎, 張　明栄
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] PEGylation modulation of peptides promotes PET detection of cancers2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
- Organizer
  eSRS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] TRT薬剤「211At-AITM」合成法の改良2021
- Author(s)
  破入　正行, 峯岸　克行, 門間　あゆみ, 謝　琳, Hu　Kuan, 張　一鼎, 藤永　雅之, 永津　弘太郎, 張　明栄
- Organizer
  第61回日本核医学会学術総会, 日本核医学会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021
- Author(s)
  Hu　Kuan, Xie Lin, Yiding Zhang, Hanyu Masayuki, Zhang Ming-Rong
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] In vivo PET imaging of cancer α5β1-integrin using a pegylated peptide2021
- Author(s)
  Hu　Kuan , 謝　琳 , 張　一鼎 , 破入　正行 , 張　明栄:
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021
- Author(s)
  Hu Kuan, Xie Lin, Hanyu Masayuki, Yiding Zhang, Zhang Ming-Rong
- Organizer
  eSRS, Society of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] ET Imaging of VEGFR with a Novel 64Cu Labeled Peptide2020
- Author(s)
  Hu Kuan, Lin Xie, Yiding Zhang, Masayuki Hanyu, Ming-Rong Zhang
- Organizer
  第60回日本核医学会学術総会, 日本核医学会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] RADIOLABELLING AND PET IMAGING OF COPPER-64 LABELED ISODGR DERIVATIVE2020
- Author(s)
  Masayuki Hanyu, Lin Xie, Hu Kuan, Yiding Zhang, Ming-Rong Zhang
- Organizer
  第57回ペプチド討論会, 日本ペプチド学会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 癌蛋白質mGluR1に基づくがん種横断的な211At-AITM標的アイソトープ治療法の開発2020
- Author(s)
  謝　琳, 張　露露, 破入　正行, 藤永　雅之, 張　一鼎, 峯岸　克行, Hu　Kuan, 李　惠子, 長谷川　純崇, 永津　弘太郎, 張　明栄
- Organizer
  第60回日本核医学会学術総会, 日本核医学会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Positron Emission Tomography Imaging of Vascular Endothelial Growth Factor Receptor Expression with a new 64Cu labeled peptide2020
- Author(s)
  Hu Kuan, Jingjie Shang, Lin Xie, Masayuki Hanyu, Yiding Zhang, Zhimin Yang, Hao Xu, Wang Lu, Ming-Rong Zhang
- Organizer
  SNMMI 2020 Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Harnessing PD-L1 interface peptide for PET imaging of PD-1 immune checkpoint2020
- Author(s)
  Hu Kuan, Lin Xie, Yiding Zhang, Masayuki Hanyu, Ming-Rong Zhang
- Organizer
  第60回日本核医学会学術総会, 日本核医学会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 転移性メラノーマに対する211At-AITMによる標的アイソトープ治療薬としての実証2019
- Author(s)
  謝琳, 破入正行, 藤永雅之, 張一鼎, 峯岸克行, 李惠子, 諸越幸恵, 長谷川純崇, 永津弘太郎, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Measurement of the metal impurity in PET probe using the HPLC post-column method2019
- Author(s)
  Masayuki Hanyu, Hideki Ishii, Nobuki Nengaki, Masanao Ogawa, Daisuke Arashi, Kenji Furutsuka, Hiroki Hashimoto, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  23nd International symposium on radiopharmaceutical science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Peptide modified and radiometals loaded BP quantum dots for targeted PET imaging-guided tumor photothermal and photodynamic therapy2019
- Author(s)
  Kuan Hu, Lin Xie, Masayuki Hanyu, Yiding Zhang, Ming-Rong Zhang
- Organizer
  23nd International symposium on radiopharmaceutical science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Develop a peptide-based PET radiotracer for imaging PD-L1 expression in cancer2019
- Author(s)
  Kuan Hu, Lin Xie, Masayuki Hanyu, Yiding Zhang, Ming-Rong Zhang
- Organizer
  23nd International symposium on radiopharmaceutical science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Radiolabeling and evaluation of isoDGR derivative using radioactive cooper2019
- Author(s)
  Masayuki Hanyu, Lin Xie, Hu Kuan, Zhimin Yang, Yiding Zhang, Hisashi Suzuki, Ming-Rong Zhang
- Organizer
  14th International Conference on Radiopharmaceutical Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 承認申請を見据えた[64Cu]Cu-ATSM注射液の品質検査法の設定2019
- Author(s)
  橋本裕輝, 破入正行, 大久保崇之, 河村和紀, 吉井幸恵, 脇厚生, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 共沈を用いたバルクZnターゲットからの67Cu分離精製法2019
- Author(s)
  大矢智幸, 永津弘太郎, 破入正行, 峯岸克行, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Separation study of silver radionuclides from a palladium target irradiated by cyclotron2019
- Author(s)
  Tomoyuki Ohya, Kotaro Nagatsu, Masayuki Hanyu, Katsuyuki Minegishi, Ming-Rong Zhang
- Organizer
  23nd International symposium on radiopharmaceutical science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] Effective therapy against melanoma using 211At labeled small-molecule radiopharmaceutical 211At-AITM by targeting oncoprotein metabotropic glutamate receptor 12019
- Author(s)
  Lin Xie, Masayuki Hanyu, Masayuki Fujinaga, Yiding Zhang, Hu Kuan, Katsuyuki Minegishi, Cuiping Jiang, Fuki Kurosawa, Yukie Morokoshi, Huizi Li, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
- Organizer
  World Molecular Imaging Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] HPLCポストカラム法を用いたPET薬剤中の金属不純物の定量2019
- Author(s)
  破入正行, 石井英樹, 念垣信樹, 小川政直, 嵐大輔, 古塚賢士, 橋本裕輝, 河村和紀, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 小分子放射性薬剤211At-AITMの合成と評価2018
- Author(s)
  破入　正行, 謝　琳, 藤永　雅之, 張　一鼎, 羽鳥　晶子, 峯岸　克行, 李　惠子, 諸越　幸恵, 長谷川　純崇, 永津　弘太郎, 張　明栄
- Organizer
  第58回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07281
[Presentation] 共沈を用いた67Cu製造法についての検討2015
- Author(s)
  大矢　智幸, 鈴木　寿, 深田　正美, 永津　弘太郎, 峯岸　克行, 破入　正行, 張　明栄
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  東京都新宿区
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] PRODUCTION OF NON-CONVENTIONAL RADIONUCLIDES WITH EMPHASIS ON TARGETRY SYSTEM DEVELOPMENT2015
- Author(s)
  Koutarou Nagatsu, Katsuyuki Minegishi, Hisashi Suzuki, Tomoyuki Ohya, Masami Fukada, Masayuki Hanyu, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  千葉県千葉市
- Year and Date
  2015-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] Carbon-11 Formaldehyde: Development of radiolabeling technique for carbon-11 labeled peptides2015
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  千葉県千葉市
- Year and Date
  2015-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] 臨床利用を目的とした64Cuの大量製造と品質評価2015
- Author(s)
  鈴木　寿, 深田　正美, 大矢　智幸, 永津　弘太郎, 峯岸　克行, 破入　正行, 山崎　慎之介, 張　明栄
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  東京都新宿区
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] Preliminary PET Study of Carbon-11 Labeled RGD Peptide by Using Carbon-11 Formaldehyde2015
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  神奈川県平塚市
- Year and Date
  2015-11-17
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] 2-[11C]メトキシピリジル基を有するH3受容体PETプローブの合成最適化の検討2014
- Author(s)
  破入正行、武井誠、橋本裕輝、古塚賢士、潮見聡、藤代智也、小川政直、念垣信樹、河村和紀、福村利光、張明栄
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] 炭素11標識した環状RGDペプチドの合成と評価2014
- Author(s)
  破入正行、須堯綾、辻厚至、河村和紀、張明栄、福村利光
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26861031
[Presentation] Radiosynthesis and preliminary PET study of an 11C-labelled RGD peptide containing [1-11C]1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid2013
- Author(s)
  Masayuki Hanyu, Atsushi Tsuji, Kazunori Kawamura, Ming-Rong Zhang, Toshimitsu Fukumura
- Organizer
  10th Australian Peptide Conference
- Place of Presentation
  Penang, MALAYSIA
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] Radiosynthesis and preliminary PET study of an <11>^C-labelled RGD peptide containing [1-<11>^C]1, 2, 3, 4-tetrahydro-beta-carboline-3-carbox ylic acid2013
- Author(s)
  Masayuki Hanyu, Atsushi Tsuji, Kazunori Kawamura, Ming-Rong Zhang, Toshimitsu Fukumura
- Organizer
  10th Australian Peptide Conference
- Place of Presentation
  Penang, MALAYSIA
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] Radiolabeling and Preliminary PET Study of Carbon-11 Labeled Amino Acids and Oligopeptides by Using Carbon-11 Formaldehyde2013
- Author(s)
  Masayuki Hanyu, Aya Sugyou, Aung U Winn, Atsushi Tsuji, Kazunori Kawamura, Tsuneo Saga, Ming-Rong Zhang, Toshimitsu Fukumura
- Organizer
  4th Asia-Pacific International Peptide Symposium, in conjunction with the 50th Japanese Peptide Symposium
- Place of Presentation
  OSAKA
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] Pictet-Spenglar反応を経由した[1-11C]-1,2,3,4-テトラヒドロ-β-カルボリン3-カルボン酸を含むオリゴペプチドの標識反応2012
- Author(s)
  破入正行
- Organizer
  第４９回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] ピクテ-スペングラー反応を用いた[11C]-テトラヒドロカルボリン誘導体の合成2012
- Author(s)
  破入正行
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] ピクテ-スペングラー反応を用いた[<11>^C]-テトラヒドロカルボリン誘導体の合成2012
- Author(s)
  破入正行, 橋本裕輝, 河村和紀, 福村利光
- Organizer
  日本核医学会
- Place of Presentation
  札幌
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] オキソンを用いた芳香族化合物への放射性塩素標識に関する研究2012
- Author(s)
  高田由貴, 破入正行, 福村利光
- Organizer
  日本核医学会
- Place of Presentation
  札幌
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-24791357
[Presentation] Pictet-Spengler 反応を経由した[1-<11>^C]1, 2, 3, 4-テトラヒドロ-β-カルボリン-3-カルボン酸を含むオリゴペプチドの標識反応2012
- Author(s)
  破入正行, 高田由貴, 橋本裕輝, 河村和紀, 張明栄, 福村利光
- Organizer
  第49回日本ペプチド学会
- Place of Presentation
  鹿児島
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-24791357

1. Xie Lin (30623558)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. 張明栄 (80443076)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
3. 胡寛 (00827678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
4. 藤永雅之 (70623726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. 水野真盛 (40271506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 張一鼎 (30872577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大矢智幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hanyu Masayuki 破入 正行

HANYU Masayuki 破入 正行

Research Projects

Research Products

Co-Researchers

糖鎖上に放射性核種をもつ診断・治療標識抗体の研究基盤の構築Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of Radio-Senolytics for Imaging and Deleting Senescent Cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of a mGluR1-targeted radiotheranostic system for tumor-agnostic cancer treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

キレーター含有糖ユニットで修飾した抗体の標識反応と評価Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis and evaluation of radioactive nanometallic agents that specifically recognize pancreatic cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Radiosynthesis and evaluation of tumor cell-penetrating oligopeptides containing short-lived positron-emitt ing radionuclidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Radiosynthesis and evaluation of peptide probe containing short-lived positron-emitting radionuclides via a Pictet-Spengler reactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated radiosynthesis of [11C]MTP38-a phosphodiesterase 7 imaging tracer using [11C]hydrogen cyanide for clinical applications2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Stable Peptide-Based PET Tracer for Detecting CD133-Expressing Cancer Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <sup>211</sup>At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer2021

Author(s)

Hanyu Masayuki 破入正行

HANYU Masayuki 破入正行