Shinohara Masakazu 篠原正和

… Alternative Names

SHINOHARA Masakazu 篠原正和

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Researcher Number	80437483
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 神戸大学, 医学研究科, 教授 2016 – 2022: 神戸大学, 医学研究科, 准教授 2017: 神戸大学, 医学(系)研究科(研究院), 准教授 2017: 神戸大学, 医学(系)研究科(研究院), 研究員 2017: 神戸大学, 大学院医学研究科, 准教授 2015: 神戸大学, 医学(系)研究科(研究院), 助教 2015: 神戸大学, 大学院医学研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Biological Sciences Except Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 56010:Neurosurgery-related / Basic Section 55060:Emergency medicine-related / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 57060:Surgical dentistry-related / Basic Section 44010:Cell biology-related … More / Cardiovascular medicine / Pediatrics / General pharmacology / Applied health science / Laboratory animal science / Neurosurgery / Laboratory medicine Less
Keywords	Principal Investigator ストレス / 動脈硬化疾患 / ストレス応答 / 脂質代謝物 / 動脈硬化 / 生理活性脂質代謝物 / 質量分析 / 脂質代謝物解析 / 虚血再灌流障害 / 脂質メディエーター … More / 虚血再灌流傷害 / 生理活性脂質メディエーター / 低比重リポ蛋白（HDL） / リポクオリティ / 高比重リポ蛋白 / ロイコトリエンB4 / 高比重リポタンパク（HDL） … More Except Principal Investigator metabolomics / 心不全 / サイトカイン / 急性脳症 / てんかん重積状態 / 熱性けいれん / 炎症 / 動脈硬化 / 熱ショックタンパク / ペントースリン酸経路 / NADPH / ペントースリン酸 / メタボロミクス / 脳虚血 / 時計遺伝子 / 概日リズム / Cushing病 / ACTH / 脱ユビキチン化酵素 / エネルギー基質選択性 / エネルギー基質変換 / インスリンシグナル / 熱産生 / FoxO1 / PDK1 / インスリン / エネルギー基質利用 / 褐色脂肪組織 / 外膜小胞 / メタボライト / denovo脂肪酸合成 / 心臓線維化 / 脂質代謝物 / 認知症 / フレイル / 脂質代謝 / Epithelial/mesenchymal / tumor / DMD / taurine / serine / slc1a5 / spindle cell sarcoma / alanine / rhabdomyosarcoma / mdx mouse / tumor suppressor / dystrophin / けいれん重積型急性脳症(AESD) / 早期診断 / 脳血流 / 脳波 / AESD / グリオーマ / グルタミン飢餓 / セリン合成 / 一炭素代謝 / metabolism / glutaminase inhibior / glutaminase inhibitor / glioma / amino acid metabolism / glioblastoma / ketogenic diet / 治療薬 / ATMキナーゼ / 脳虚血再灌流障害 / 脳梗塞 / 脳虚血再灌流 / Geranylgeranylacetone / geranylgeranylacetone / heat shock protein / stroke / ischemia reperfusion / 熱ショックタンパク質 / 虚血再灌流障害 / 熱ショック蛋白 / 炎症性サイトカイン / けいれん重積 / てんかん重積 / GDF-15 / 循環器 / 脂質代謝異常 / コレステロール引き抜き / 高比重リポタンパク質 / リポタンパク質 / オメガ3系多価不飽和脂肪酸 / 逆転送 / コレステロール / エイコサペンタエン酸 / HDL / 脂質異常症 / 冠動脈疾患 / コレステロール逆転送 / 高比重リポ蛋白 / 新規治療法 / 潜在性エクソン / スプライシング / SMN2遺伝子 / SMN1遺伝子 / オフターゲット効果 / ヌシネルセン / アンチセンスオリゴヌクレオチド / スプライス部位 / イントロン・リテンション / SMN２遺伝子 / SMN１遺伝子 / 脊髄性筋萎縮症 / プロスタグランディン / 炎症・免疫 / H-PGDS阻害薬 / プロスタグランディンD2 / 心筋線維化 / 自己免疫性心筋炎 / 脂質 / 生体分子 / 分析科学 / 循環器・高血圧 / リハビリテーション / 心血管疾患 / 有酸素運動 / 抗炎症効果 / 運動療法 / 脂質メディエーター / 心臓リハビリテーション / WHHLMIウサギ / メタボーローム解析 / 血清マーカー / 疾患モデル / 冠動脈病変 / 心筋梗塞 / バイオマーカー / 疾患モデル動物 / トランスクリプトミクス / オミクス / 脳代謝 / pentose phosphate / cerebral ischemia / メタボローム / 石灰化病変 / メタボローム解析 / 画像診断 / 大動脈石灰化病変 Less

Mechanistic Investigation of ACTH Regulation Mediated by the USP Family of Deubiquitinating Enzymes
- Principal Investigator
  
  福岡秀規
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kobe University
Development of Novel Diagnostic and Therapeutic Approaches Targeting Clock Genes for Heart Failure
- Principal Investigator
  
  金城健太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
超高齢社会における健康寿命延伸に寄与する脂質代謝物の探索的研究
- Principal Investigator
  
  石田達郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
de novo 脂肪酸合成経路に着目した心臓線維化の分子機序解明と治療法の確立
- Principal Investigator
  
  小林成美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
微生物由来メタボライトと外膜小胞の機能解析による口腔粘膜炎発症機序の解明
- Principal Investigator
  
  長谷川温
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical University
オキソ脂肪酸がつなぐ「脳・こころ」ストレスと動脈硬化疾患Principal Investigator
- Principal Investigator
  
  篠原正和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Metabolomic analysis of Mdx mouse tumors
- Principal Investigator
  
  ニバタベ・エマ・エコ
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Juntendo University
Elucidation of pathophysiology and trigger of AESD using EEG, inflammatory markers, and cerebral blood flow analysis.
- Principal Investigator
  
  永瀬裕朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kobe University
Regulatory mechanisms of fuel utilization in brown adipose tissue thermogenesis
- Principal Investigator
  
  細岡哲也
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Shizuoka
"Brain-Mind" Stress and Atherosclerotic Disease: Mechanisms Unveiled through Lipid Metabolite AnalysisPrincipal Investigator
- Principal Investigator
  
  Shinohara Masakazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Basic research of ketogenic diet therapy with inhibitor of aminno acid metabolism for glioblastoma
- Principal Investigator
  
  Sasayama Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kobe University
One carbon metabolism for glioma cells to survive glutamine starvation
- Principal Investigator
  
  TANAKA KAZUHIRO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kobe University
Elucidation of the pathophysiology of refractory status epilepticus by comprehensive inflammation analysis and development of new diagnosis and treatment methods
- Principal Investigator
  
  Nagase Hiroaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kobe University
Elucidation of the role of ATM kinase pathway in cerebral ischemia-reperfusion injury and its application to new cerebral infarction therapy
- Principal Investigator
  
  Hosoda Kohkichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kobe University
Elucidation of bioactive lipid mediators related to ischemia-reperfusion injury and development of novel treatment strategyPrincipal Investigator
- Principal Investigator
  
  Shinohara Masakazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kobe University
New Treatment Strategy for SMA: In tron-retention of the SMN2 gene
- Principal Investigator
  
  Nishio Hisahide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe Gakuin University
  Kobe University
高比重リポ蛋白（HDL）機能を制御する脂質クオリティPrincipal Investigator
- Principal Investigator
  
  篠原正和
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
The regulatory mechanisms of inflammation by exercise via lipid mediators
- Principal Investigator
  
  Kobayashi Seimi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kobe University
Regulation of cardiac remodeling by inhibiting the PGD2-mediated inflammatory response.
- Principal Investigator
  
  Ikeda Yuichi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Discovery of novel treatment strategy for aortic calcification through CT imaging and metabolome analysis
- Principal Investigator
  
  Takaya Tomofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe University
Comprehennsive analysis of cerebral metabolic changes during ischemia-reperfusion by omics
- Principal Investigator
  
  Hosoda Kohkichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
Clinical significance of cholesterol uptake capacity, a novel assay of high-density lipoprotein function, in coronary artery disease
- Principal Investigator
  
  Tatsuro Ishida
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kobe University
Examination of biomarker for myocardial infarction and coronary atherosclerosis
- Principal Investigator
  
  Shiomi Masashi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kobe University

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All Journal Article Presentation Book Patent

[Book] 実験医学『脂質が支えるバイオロジー』高比重リポ蛋白（HDL）機能を制御するリポクオリティ2018
- Author(s)
  篠原正和・平田健一
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Journal Article] Stress-induced stenotic vascular remodeling via reduction of plasma omega-3 fatty acid metabolite 4-oxoDHA by noradrenaline2024
- Author(s)
  Nishimori Makoto、Hayasaka Naomi、Otsui Kazunori、Inoue Nobutaka、Asakura Junko、Nagao Manabu、Toh Ryuji、Ishida Tatsuro、Hirata Ken-ichi、Furuyashiki Tomoyuki、Shinohara Masakazu
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 4178-4178
- DOI
  10.1038/s41598-024-54867-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07577, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812
[Journal Article] Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen2024
- Author(s)
  Horikawa Io、Nagai Hirotaka、Taniguchi Masayuki、Chen Guowei、Shinohara Masakazu、Suzuki Tomohide、Ishii Shinichi、Katayama Yoshio、Kitaoka Shiho、Furuyashiki Tomoyuki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 4 Pages: 279-293
- DOI
  10.1016/j.jphs.2024.02.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1560, KAKENHI-PROJECT-18KK0055, KAKENHI-PROJECT-23K06358, KAKENHI-PROJECT-23K06359, KAKENHI-PROJECT-23K07577, KAKENHI-PROJECT-21K06576, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812
[Journal Article] Correction: Noguchi et al. PCR-Based Screening of Spinal Muscular Atrophy for Newborn Infants in Hyogo Prefecture, Japan. Genes 2022, 13, 21102023
- Author(s)
  Noguchi Yoriko、Bo Ryosuke、Nishio Hisahide、Matsumoto Hisayuki、Matsui Keiji、Yano Yoshihiko、Sugawara Masami、Ueda Go、Wijaya Yogik Onky Silvana、Niba Emma Tabe Eko、Shinohara Masakazu、Bouike Yoshihiro、Takeuchi Atsuko、Lee Tomoko、Takeshima Yasuhiro、Iijima Kazumoto、Nozu Kandai、Awano Hiroyuki
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 3 Pages: 759-759
- DOI
  10.3390/genes14030759
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06224
[Journal Article] Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice2022
- Author(s)
  Akiyama Satoshi、Nagai Hirotaka、Oike Shota、Horikawa Io、Shinohara Masakazu、Lu Yabin、Futamura Takashi、Shinohara Ryota、Kitaoka Shiho、Furuyashiki Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 11385-11385
- DOI
  10.1038/s41598-022-15461-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06576, KAKENHI-PROJECT-22K06859, KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-20K07288, KAKENHI-PROJECT-20K08422, KAKENHI-PLANNED-18H05429
[Journal Article] PCR-Based Screening of Spinal Muscular Atrophy for Newborn Infants in Hyogo Prefecture, Japan2022
- Author(s)
  Noguchi Yoriko、Bo Ryosuke、Nishio Hisahide、Matsumoto Hisayuki、Matsui Keiji、Yano Yoshihiko、Sugawara Masami、Ueda Go、Wijaya Yogik Onky Silvana、Niba Emma Tabe Eko、Shinohara Masakazu、Bouike Yoshihiro、Takeuchi Atsuko、Okamoto Kentaro、Saito Toshio、Shimomura Hideki、Lee Tomoko、Takeshima Yasuhiro....Awano Hiroyuki
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 11 Pages: 2110-2110
- DOI
  10.3390/genes13112110
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06224, KAKENHI-PROJECT-20K08197
[Journal Article] High Concentration or Combined Treatment of Antisense Oligonucleotides for Spinal Muscular Atrophy Perturbed SMN2 Splicing in Patient Fibroblasts2022
- Author(s)
  Wijaya Yogik Onky Silvana、Niba Emma Tabe Eko、Nishio Hisahide、Okamoto Kentaro、Awano Hiroyuki、Saito Toshio、Takeshima Yasuhiro、Shinohara Masakazu
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 4 Pages: 685-685
- DOI
  10.3390/genes13040685
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06224, KAKENHI-PROJECT-20K08197
[Journal Article] Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study2021
- Author(s)
  Matsuo, Kazuya and Hosoda, Kohkichi and Tanaka, Jun and Yamamoto, Yusuke and Imahori, Taichiro and Nakai, Tomoaki and Irino, Yasuhiro and Shinohara, Masakazu and Sasayama, Takashi and Kohmura, Eiji
- Journal Title
  
  BMC Neuroscience
  
  Volume: 22 Issue: 1 Pages: 9-19
- DOI
  10.1186/s12868-021-00614-7
- NAID
  120006975748
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994, KAKENHI-PROJECT-20K09369, KAKENHI-PROJECT-20K17968
[Journal Article] Canagliflozin ameliorates hepatic fat deposition in obese diabetic mice: Role of prostaglandin E22021
- Author(s)
  Yoshino Kei、Hosooka Tetsuya、Shinohara Masakazu、Aoki Chikako、Hosokawa Yusei、Imamori Makoto、Ogawa Wataru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 557 Pages: 62-68
- DOI
  10.1016/j.bbrc.2021.04.012
- NAID
  120007185893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03355
[Journal Article] Glioma cells require one-carbon metabolism to survive glutamine starvation.2021
- Author(s)
  Tanaka K*, Sasayama T, Nagashima H, Irino Y, Takahashi M, Izumi Y, Uno T, Satoh N, Kitta A, Kyotani K, Fujita Y, Hashiguchi M, Nakai T, Kohta M, Uozumi Y, Shinohara M, Hosoda K, Bamba T, Kohmura E.
- Journal Title
  
  Acta Neuropathol. Commun.
  
  Volume: 9 Issue: 1 Pages: 16-16
- DOI
  10.1186/s40478-020-01114-1
- NAID
  120006956370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-20K09369
[Journal Article] Metabolic changes and anti-tumor effects of a ketogenic diet combined with anti-angiogenic therapy in a glioblastoma mouse model2021
- Author(s)
  Maeyama Masahiro、Tanaka Kazuhiro、Nishihara Masamitsu、Irino Yasuhiro、Shinohara Masakazu、Nagashima Hiroaki、Tanaka Hirotomo、Nakamizo Satoshi、Hashiguchi Mitsuru、Fujita Yuichi、Kohta Masaaki、Kohmura Eiji、Sasayama Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 79-79
- DOI
  10.1038/s41598-020-79465-x
- NAID
  120007026367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18391, KAKENHI-PROJECT-18K08943, KAKENHI-PROJECT-20K09369, KAKENHI-PROJECT-20K09389
[Journal Article] Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity2021
- Author(s)
  Yoshida Naofumi、Yamashita Tomoya、Osone Tatsunori、Shinohara Masakazu、Kitahama Seiichi、Sasaki Kengo、Sasaki Daisuke、Emoto Takuo、Saito Yoshihiro、Kitaura Yasuyuki、Shimomura Yoshiharu、Kondo Akihiko、Kajimura Shingo、Inagaki Takeshi、Yamada Takuji、Hirata Ken-ichi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 11 Pages: 103342-103342
- DOI
  10.1016/j.isci.2021.103342
- NAID
  120007179184
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03653, KAKENHI-PROJECT-20H03676, KAKENHI-PROJECT-18K11013, KAKENHI-PROJECT-21K08548, KAKENHI-PROJECT-20K22647, KAKENHI-PROJECT-20H03729, KAKENHI-PROJECT-21H03355
[Journal Article] Stability and Oligomerization of Mutated SMN Protein Determine Clinical Severity of Spinal Muscular Atrophy2021
- Author(s)
  Niba ETE, Nishio H, Wijaya YOS, Ar Rochmah M, Takarada T, Takeuchi A, Kimizu T, Okamoto K, Saito T, Awano H, Takeshima Y, Shinohara M.
- Journal Title
  
  Genes (Basel)
  
  Volume: 13 Issue: 2 Pages: 205-205
- DOI
  10.3390/genes13020205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08197, KAKENHI-PROJECT-22K06224
[Journal Article] In Vivo Imaging of Venous Thrombus and Pulmonary Embolism Using Novel Murine Venous Thromboembolism Model2020
- Author(s)
  Okano Mitsumasa、Hara Tetsuya、Nishimori Makoto、Irino Yasuhiro、Satomi-Kobayashi Seimi、Shinohara Masakazu、Toh Ryuji、Jaffer Farouc A.、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 5 Issue: 4 Pages: 344-356
- DOI
  10.1016/j.jacbts.2020.01.010
- NAID
  120006952759
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-19K08516
[Journal Article] Effect of rosuvastatin and eicosapentaenoic acid on neoatherosclerosis: the LINK-IT Trial2019
- Author(s)
  Kuroda K, Otake H, Shinohara M, Kuroda M, Tsuda S, Toba T, Nagano Y, Toh R, Ishida T, Shinke T, Hirata KI.
- Journal Title
  
  EuroIntervention
  
  Volume: 15 Issue: 12 Pages: e1099-e1106
- DOI
  10.4244/eij-d-18-01073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09553, KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-17K09579
[Journal Article] Elevated Serum Elaidic Acid Predicts Risk of Repeat Revascularization After Percutaneous Coronary Intervention in Japan2019
- Author(s)
  Oshita Toshihiko、Toh Ryuji、Shinohara Masakazu、Mori Kenta、Irino Yasuhiro、Nagao Manabu、Hara Tetsuya、Otake Hiromasa、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 5 Pages: 1032-1038
- DOI
  10.1253/circj.CJ-18-1175
- NAID
  130007636975
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-04-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-17K09579
[Journal Article] Serum concentration of full-length- and carboxy-terminal fragments of endothelial lipase predicts future cardiovascular risks in patients with coronary artery disease2019
- Author(s)
  Nagao Manabu、Miyashita Kazuya、Mori Kenta、Irino Yasuhiro、Toh Ryuji、Hara Tetsuya、Hirata Ken-ichi、Shinohara Masakazu、Nakajima Katsuyuki、Ishida Tatsuro
- Journal Title
  
  Journal of Clinical Lipidology
  
  Volume: 13 Issue: 5 Pages: 839-846
- DOI
  10.1016/j.jacl.2019.07.007
- NAID
  120007002630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-18K08073, KAKENHI-PROJECT-17K09579
[Journal Article] A Novel System for Spinal Muscular Atrophy Screening in Newborns: Japanese Pilot Study2019
- Author(s)
  Shinohara M, Niba ETE, Nishio H, et al.
- Journal Title
  
  International Journal of Neonatal Screening
  
  Volume: 5 Issue: 4 Pages: 41-41
- DOI
  10.3390/ijns5040041
- NAID
  120006811121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Identification of novel serum markers for the progression of coronary atherosclerosis in WHHLMI rabbits, an animal model of familial hypercholesterolemia2019
- Author(s)
  Shiomi Masashi、Takeda Hiroaki、Irino Yasuhiro、Kimura Norie、Yamada Satoshi、Kuniyoshi Nobue、Kikumori Akio、Koike Yu、Koike Tomonari、Yoshida Masaru、Izumi Yoshihiro、Shinohara Masakazu、Bamba Takeshi、Ishida Tatsuro
- Journal Title
  
  Atherosclerosis
  
  Volume: 284 Pages: 18-23
- DOI
  10.1016/j.atherosclerosis.2019.02.020
- NAID
  120006850489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-23300157, KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-18H01800
[Journal Article] Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients With Decompensated and Compensated Heart Failure2018
- Author(s)
  Hayashi T, Yamashita T, Watanabe H, Kami K, Yoshida N, Tabata T, Emoto T, Sasaki N, Mizoguchi T, Irino Y, Toh R, Shinohara M, Okada Y, Ogawa W, Yamada T, Hirata K.
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 1 Pages: 182-192
- DOI
  10.1253/circj.CJ-18-0468
- NAID
  130007550393
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-12-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09497, KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-16H06279
[Journal Article] Intron-retained transcripts of the spinal muscular atrophy genes, SMN1 and SMN2.2018
- Author(s)
  Harahap NIF, Niba ETE, Ar Rochmah M, Wijaya YOS, Saito T, Saito K, Awano H, Morioka I, Iijima K, Lai PS, Matsuo M, Nishio H, Shinohara M.
- Journal Title
  
  Brain & Devwlopment
  
  Volume: 40 Issue: 8 Pages: 670-677
- DOI
  10.1016/j.braindev.2018.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10077, KAKENHI-PROJECT-16K07216
[Journal Article] Eicosapentaenoic Acid-Enriched High-Density Lipoproteins Exhibit Anti-Atherogenic Properties2018
- Author(s)
  6.Tanaka N, Irino Y, Shinohara M, Tsuda S, Mori T, Nagao M, Oshita T, Mori K, Hara T, Toh R, Ishida T, Hirata K
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 2 Pages: 596-601
- DOI
  10.1253/circj.CJ-17-0294
- NAID
  130006321869
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09121
[Journal Article] Eicosapentaenoic Acid-Enriched High-Density Lipoproteins Exhibit Anti-Atherogenic Properties.2018
- Author(s)
  Tanaka N, Irino Y, Shinohara M, Tsuda S, Mori T, Nagao M, Oshita T, Mori K, Hara T, Toh R, Ishida T, Hirata KI.
- Journal Title
  
  Circulation Journal
  
  Volume: 82 Pages: 596-601
- NAID
  130006321869
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Journal Article] Modulation of lipid mediator profile may contribute to amelioration of chronic inflammation in adipose tissue of obese mice by pioglitazone2018
- Author(s)
  Okada Kumiko、Hosooka Tetsuya、Shinohara Masakazu、Ogawa Wataru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 1 Pages: 29-35
- DOI
  10.1016/j.bbrc.2018.09.081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-18K08478
[Journal Article] Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion2018
- Author(s)
  Yamamoto Yusuke、Hosoda Kohkichi、Imahori Taichiro、Tanaka Jun、Matsuo Kazuya、Nakai Tomoaki、Irino Yasuhiro、Shinohara Masakazu、Sato Naoko、Sasayama Takashi、Tanaka Kazuhiro、Nagashima Hiroaki、Kohta Masaaki、Kohmura Eiji
- Journal Title
  
  Brain Research
  
  Volume: 1687 Pages: 82-94
- DOI
  10.1016/j.brainres.2018.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10302, KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-17K10863, KAKENHI-PROJECT-17K10898, KAKENHI-PROJECT-18K08943
[Journal Article] NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis via Increased Lipoxin B4 Synthesis.2017
- Author(s)
  Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AM.
- Journal Title
  
  Am J Respir Crit Care Med.
  
  Volume: 印刷中 Issue: 6 Pages: 713-726
- DOI
  10.1164/rccm.201604-0892oc
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Journal Article] Spinal muscular atrophy carriers with two SMN1 copies2017
- Author(s)
  Ar Rochmah Mawaddah、Awano Hiroyuki、Awaya Tomonari、Harahap Nur Imma Fatimah、Morisada Naoya、Bouike Yoshihiro、Saito Toshio、Kubo Yuji、Saito Kayoko、Lai Poh San、Morioka Ichiro、Iijima Kazumoto、Nishio Hisahide、Shinohara Masakazu
- Journal Title
  
  Brain and Development
  
  Volume: 39 Issue: 10 Pages: 851-860
- DOI
  10.1016/j.braindev.2017.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Enhanced Impact of Cholesterol Absorption Marker on New Atherosclerotic Lesion Progression After Coronary Intervention During Statin Therapy2017
- Author(s)
  Mori K, Ishida T, Tsuda S, Oshita T, Shinohara M, Hara T, Irino Y, Toh R, Hirata KI.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 2 Pages: 123-132
- DOI
  10.5551/jat.32615
- NAID
  130005306526
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-15K09121
[Journal Article] High-density lipoprotein protects cardiomyocytes from oxidative stress via the PI3K/mTOR signaling pathway2017
- Author(s)
  Nagao Manabu、Toh Ryuji、Irino Yasuhiro、Nakajima Hideto、Oshita Toshihiko、Tsuda Shigeyasu、Hara Tetsuya、Shinohara Masakazu、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 7 Issue: 9 Pages: 1402-1409
- DOI
  10.1002/2211-5463.12279
- NAID
  120006373788
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-15K09121
[Journal Article] Excessive intake of trans fatty acid accelerates atherosclerosis through promoting inflammation and oxidative stress in a mouse model of hyperlipidemia.2017
- Author(s)
  Monguchi T, Hara T, Hasokawa M, Nakajima H, Mori K, Toh R, Irino Y, Ishida T, Hirata KI, Shinohara M
- Journal Title
  
  J Cardiol
  
  Volume: 印刷中 Issue: 2 Pages: 121-127
- DOI
  10.1016/j.jjcc.2016.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-26461109, KAKENHI-PROJECT-15K21154, KAKENHI-PROJECT-15K09121
[Journal Article] Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages2017
- Author(s)
  Tsuda Shigeyasu、Shinohara Masakazu、Oshita Toshihiko、Nagao Manabu、Tanaka Nobuaki、Mori Takeshige、Hara Tetsuya、Irino Yasuhiro、Toh Ryuji、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12989-12989
- DOI
  10.1038/s41598-017-13154-0
- NAID
  120006373799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-15K09121
[Journal Article] Genetic screening of spinal muscular atrophy using a real-time modified COP-PCR technique with dried blood-spot DNA2017
- Author(s)
  Ar Rochmah M, Harahap NIF, Niba ETE, Nakanishi K, Awano H, Morioka I, Iijima K, Saito T, Saito K, Lai PS, Takeshima Y, Takeuchi A, Bouike Y, Okamoto M, Nishio H, Shinohara M
- Journal Title
  
  Brain Dev.
  
  Volume: 39(9) Issue: 9 Pages: 774-782
- DOI
  10.1016/j.braindev.2017.04.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07216, KAKENHI-PROJECT-17K10077
[Journal Article] Combined metabolic and transcriptional profiling identifies pentose phosphate pathway activation by HSP27 phosphorylation during cerebral ischemia.2017
- Author(s)
  Imahori T, Hosoda K, Nakai T, Yamamoto Y, Irino Y, Shinohara M, Sato N, Sasayama T, Tanaka K, Nagashima H, Kohta M, Kohmura E.
- Journal Title
  
  Neuroscience.
  
  Volume: 349 Pages: 1-16
- DOI
  10.1016/j.neuroscience.2017.02.036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10863, KAKENHI-PROJECT-15K10302
[Journal Article] G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.2017
- Author(s)
  Kawano Y, Fukui C, Shinohara M, Wakahashi K, Ishii S, Suzuki T, Sato M, Asada N, Kawano H, Minagawa K, Sada A, Furuyashiki T, Uematsu S, Akira S, Uede T, Narumiya S, Matsui T, Katayama Y.
- Journal Title
  
  Blood
  
  Volume: 129 Issue: 5 Pages: 587-597
- DOI
  10.1182/blood-2016-07-725754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01289, KAKENHI-PUBLICLY-15H01367, KAKENHI-PUBLICLY-15H01512, KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-15K14404
[Journal Article] SMA mutations in SMN Tudor and C-terminal domains destabilize the protein2017
- Author(s)
  Takarada Toru、Ar Rochmah Mawaddah、Harahap Nur Imma Fatimah、Shinohara Masakazu、Saito Toshio、Saito Kayoko、Lai Poh San、Bouike Yoshihiro、Takeshima Yasuhiro、Awano Hiroyuki、Morioka Ichiro、Iijima Kazumoto、Nishio Hisahide、Takeuchi Atsuko
- Journal Title
  
  Brain and Development
  
  Volume: 39 Issue: 7 Pages: 606-612
- DOI
  10.1016/j.braindev.2017.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] 機能性脂質・脂肪酸の多彩な生理活性と病態形成：トランス脂肪酸と血管医学2016
- Author(s)
  篠原正和・石田達郎・平田健一
- Journal Title
  
  血管医学
  
  Volume: 17 Pages: 183-190
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Journal Article] 高HDL-C血症2016
- Author(s)
  篠原正和, 石田達郎
- Journal Title
  
  Medical Practice
  
  Volume: 33 Pages: 575-580
- Data Source
  KAKENHI-PROJECT-15K09121
[Journal Article] 2-Aminobutyric acid modulates glutathione homeostasis in the myocardium.2016
- Author(s)
  Irino Y, Toh R, Nagao M, Mori T, Honjo T, Shinohara M, Tsuda S, Nakajima H, Satomi-Kobayashi S, Shinke T, Tanaka H, Ishida T, Miyata O, Hirata KI.
- Journal Title
  
  Sci Rep.
  
  Volume: - Issue: 1 Pages: 36749-36749
- DOI
  10.1038/srep36749
- NAID
  120005898711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01361, KAKENHI-PROJECT-26461070, KAKENHI-PROJECT-15K21154, KAKENHI-PROJECT-15K09081
[Journal Article] 脂質異常症の臨床：高HDL血症2016
- Author(s)
  篠原正和・石田達郎
- Journal Title
  
  Medical Practice
  
  Volume: 33 Pages: 575-580
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Patent] SNP検出方法2017
- Inventor(s)
  西尾久英、篠原正和
- Industrial Property Rights Holder
  西尾久英、篠原正和
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-196967
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] 腸内細菌代謝物を介するピオグリタゾンのNASH改善メカニズムの解明2022
- Author(s)
  笠原南々帆、伊美友紀子、天野礼菜、篠原正和、岡田久美子、細川友誠、今森真、嶋田渉、富本千晶、岸野重信、小川順、小川渉、細岡哲也
- Organizer
  26回日本病態栄養学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H03355
[Presentation] カナグリフロジンによるNAFLD改善効果のメカニズムの解明2021
- Author(s)
  芳野啓，細岡哲也，篠原正和，小川渉
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H03355
[Presentation] 脂肪細胞特異的LTA4H過剰発現は肥満による代謝障害の発症を抑制する2021
- Author(s)
  細川友誠，細岡哲也，篠原正和，小川渉
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H03355
[Presentation] Activate the Pentose Phosphate Pathway to Reduce the Cerebral Ischemia/Reperfusion Injury: The Impact of Heat Shock Protein 27 Phosphorylation2019
- Author(s)
  Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Takashi Sasayama, Eiji Kohmura
- Organizer
  International Stroke Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 脳虚血再灌流障害に対する Heat shock protein 27リン酸化誘導による神経保護治療：メタボロミクス研究から治療応用へ．2019
- Author(s)
  9.松尾和哉, 細田弘吉, 田中潤, 山本祐輔, 今堀太一郎, 中井友昭, 入野康宏, 篠原正和, 篠山隆司, 甲村英二．
- Organizer
  日本脳神経外科学会第78回学術総会　2019年10月9日　大阪国際会議場（グランキューブ大阪）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 脳虚血再灌流障害に対する Heat shock protein 27リン酸化誘導による神経保護治療：オミクス研究から治療へ．特別シンポジウム1『時間で追う脳虚血の病態と治療:1急性期』2019
- Author(s)
  13.松尾和哉, 細田弘吉, 田中潤, 山本祐輔, 今堀太一郎, 中井友昭, 入野康宏, 篠原正和, 篠山隆司, 甲村英二．
- Organizer
  第62回日本脳循環代謝学会学術集会2019年11月29日　江陽グランドホテル（仙台）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Phosphorylation of Heat Shock Protein 27 Leads to Activation of Pentose Phosphate Pathway and Protection from Cerebral Ischemia-Reperfusion Injury2019
- Author(s)
  3.Matsuo K, Hosoda K, Tanaka J, Yamamoto Y, Imahori T, Nakai T, Irino Y, Shinohara M, Sasayama T, Kohmura E
- Organizer
  Brain & Brain PET 2019, Yokohama (Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 虚血再灌流時のHeat shock protein 27リン酸化によるペントースリン酸経路亢進: オミクス研究から治療応用へ2019
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第44回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Heat shock protein 27リン酸化誘導による脳虚血再灌流時の神経保護:オミクス研究から臨床応用へ2019
- Author(s)
  7.松尾和哉，細田弘吉，田中潤，山本祐輔，今堀太一郎，中井友昭，入野康宏，篠原正和，篠山隆司，甲村英二．
- Organizer
  第20回日本分子脳神経外科学会　2019年8月9日　秋葉原コンベンションホール（東京）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Upregulation of Pentose Phosphate Pathway after Focal Cerebral Ischemia/Reperfusion Injury in Rat Cerebral Cortex: The Impact of Heat Shock Protein 27 Phosphorylation2018
- Author(s)
  Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka1, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Eiji Kohmura
- Organizer
  International Stroke Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] 虚血後再灌流による脳皮質でのペントースリン酸経路の賦活化 -オミクス解析による分析とHeat shock protein 27の関与-2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第19回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 虚血再灌流による脳皮質ペントースリン酸経路の亢進　オミクス研究を基に探るHeat shock protein 27 の役割2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第62回日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] WHHLMIウサギにおける冠動脈病変の発生・進行に関わる血漿マーカーの同定2018
- Author(s)
  塩見雅志、竹田浩章、入野康宏、ユウイン、小池智也、和泉自泰、篠原正和、馬場健史、石田達郎
- Organizer
  第50回日本動脈硬化学会総会・学術集会(大阪)
- Data Source
  KAKENHI-PROJECT-23300157
[Presentation] WHHLMIウサギにおける冠動脈病変の発生・進行に関わる血漿マーカー2018
- Author(s)
  塩見雅志、竹田浩章、入野康宏、ユウイン、小池智也、和泉自泰、篠原正和、馬場健史、石田達郎
- Organizer
  第65回日本実験動物学会総会・学術集会(富山)
- Data Source
  KAKENHI-PROJECT-23300157
[Presentation] Development of markers for progression of coronary plaques using WHHLMI rabbits, an animal model of familial hypercholesterolemia2018
- Author(s)
  Masashi Shiomi, Hiroaki Takeda, Yasuhiro Irino, Satoshi Yamada, Nobue Kuniyoshi, Yu Ying, Tomonari Koike, Yoshihiro Izumi, Masakazu Shinohara, Takeshi Bamba, Tatsuro Ishida
- Organizer
  86^<th> European Atherosclerosis Society Congress (Lisbon, Portugal)
- Data Source
  KAKENHI-PROJECT-23300157
[Presentation] 虚血再灌流による脳皮質でのペントースリン酸経路の賦活化オミクス解析による分析と Heat shock protein 27 の役割2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  日本脳神経外科学会第77回学術総会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Identification of novel lipid markers for coronary atherosclerosis in WHHLMI rabbits, an animal model of familial hypercholesterolemia.2018
- Author(s)
  Masashi Shiomi, Hiroaki Takeda, Yasuhiro Irino, Satoshi Yamada, Nobue Kuniyoshi, Yu Ying, Tomonari Koike, Yoshihiro Izumi, Masakazu Shinohara, Takeshi Bamba, Tatsuro Ishida
- Organizer
  XVIII International Symposium on Atherosclerosis (Toronto, Canada)
- Data Source
  KAKENHI-PROJECT-23300157
[Presentation] Novel Mechanism of High-Density Lipoprotein to Regulate 5-Lipoxygenase/Leukotriene B4 Pathway in Macrophages.2017
- Author(s)
  Tsuda S, Shinohara M, Okano M, Oshita T, Hara T, Irino Y, Toh R, Ishida T, and Hirata KI.
- Organizer
  The Scientific Sessions of the American Heart Association, 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Presentation] Combined Metabolic And Transcriptional Profiling Identifies Pentose Phosphate Pathway Activation by Heat Shock Protein 27 Phosphorylation During Cerebral Ischemia2017
- Author(s)
  YUSUKE YAMAMOTO, Kohkichi Hosoda, Jun Tanaka, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Naoko Sato, Eiji Kohmura
- Organizer
  International Stroke Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] De novo leukotriene B4 production from high density lipoproteins (HDL) in recurrent cardiovascular disease patients deteriorates anti-inflammatory properties of HDL.2017
- Author(s)
  Shigeyasu Tsuda, Masakazu Shinohara, et.al
- Organizer
  日本循環器学会総会　2017
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Presentation] De novo leukotriene B4 production from high density lipoproteins (HDL) in recurrent cardiovascular disease patients deteriorates anti-inflammatory properties of HDL.2016
- Author(s)
  Shigeyasu Tsuda, Masakazu Shinohara, et.al
- Organizer
  American Heart Association 2016
- Place of Presentation
  New Orleans
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Presentation] 高比重リポ蛋白 (HDL) の抗炎症効果はリン脂質構成に依存する2016
- Author(s)
  Tanaka N, Irino Y, Shinohara M, Tsuda S, Nagao M, Mori K, Mori T, Hara T, Toh R, Ishida T, Hirata K.
- Organizer
  第48回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K09121
[Presentation] 虚血脳組織のオミクス解析による脳虚血中HSP27リン酸化を介するペントースリン酸経路活性化の同定2016
- Author(s)
  山本祐輔、細田弘吉、入野康宏、篠原正和、今堀太一郎、田中潤、中井友昭、甲村英二
- Organizer
  日本脳神経外科学会第 75 回学術総会
- Place of Presentation
  福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] High-Density Lipoproteins from Coronary Artery Disease Patients Contribute to Inflammatory-prone Lipid Mediator Production.2016
- Author(s)
  Tsuda S, Shinohara M, Irino Y, Mori K, Tanaka N, Ishida T, Hirata K.
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K09121
[Presentation] HDLはマクロファージへエンドサイトーシスされることで5-LO/LTB4炎症シグナルを制御する-健常群HDLと冠動脈症例HDLとの比較2016
- Author(s)
  篠原正和
- Organizer
  第48回日本動脈硬化学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-16H01361
[Presentation] 脳組織のオミクス解析による脳虚血中HSP27リン酸化を介するペントースリン酸経路活性化の同定2016
- Author(s)
  山本祐輔、細田弘吉、入野康宏、篠原正和、今堀太一郎、田中潤、中井友昭、甲村英二
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] METABOLIC PROFILING TO IDENTIFY DISTINCT CHANGES ASSOCIATED WITH ISCHEMIC CEREBROVASCULAR EVENTS 385 IN CAROTID STENOSIS2015
- Author(s)
  T. Nakai, K. Hosoda, T. Imahori, M. Shinohara, Y. Irino, M. Yoshida, E. Kohmura
- Organizer
  Brain 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] Serum myeloperoxidase/paraoxonase 1 ration predicts recurrent coronary artery disease2015
- Author(s)
  Tsuda S, Toh R, Mori K, Nagao M, Tanaka N, Mori T, Monguchi T, Nakajima H, Honjo T, Shinohara M, Nishimura K, Ishida T, Hirata K
- Organizer
  ATVB/PVD2015
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2015-05-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09121
[Presentation] 冠動脈疾患二次予防における予測因子としての血清ミエロペルオキシダーゼ/パラオキソナーゼ1比の有用性についての検討2015
- Author(s)
  Tsuda S, Toh R, Mori K, Nagao M, Tanaka N, Mori T, Monguchi T, Nakajima H, Honjo T, Shinohara M, Nishimura K, Ishida T, Hirata K
- Organizer
  第15回日本NO学会
- Place of Presentation
  大阪
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K09121
[Presentation] Serum Myeloperoxidase/Paraoxonase 1 Ratio Predicts Recurrent Coronary Artery Disease2015
- Author(s)
  Tsuda S, Toh R, Mori K, Nagao M, Tanaka N, Mori T, Monguchi T, Nakajima H, Honjo T, Shinohara M, Nishimura K, Ishida T, Hirata K
- Organizer
  第47回日本動脈硬化学会総会学術集会
- Place of Presentation
  仙台
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K09121

1. ISHIDA Tatsuro (00379413)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. Sasayama Takashi (10379399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. TOH Ryushi (50379418)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. 長尾学 (70866029)

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5. SHINKE Toshiro (60379419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. HIRATA Ken-ichi (20283880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. Hosoda Kohkichi (90403261)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
8. Kobayashi Seimi (20379415)

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12. Takaya Tomofumi (60714665)

# of Collaborated Projects: 1 results

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13. Shiomi Masashi (50226106)

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# of Collaborated Products: 4 results
14. ITO Takashi (30135793)

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15. KOIKE Tomonari (40432158)

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16. Ikeda Yuichi (10744419)

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17. URADE Yoshihiro (10201360)

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38. KITAOKA Shiho

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39. AWANO HIROYUKI

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40. YAMASHITA Tomoya

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41. FURUYASHIKI Tomoyuki

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42. 和泉自泰

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43. 入野康宏

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Shinohara Masakazu 篠原 正和

SHINOHARA Masakazu 篠原 正和

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オキソ脂肪酸がつなぐ「脳・こころ」ストレスと動脈硬化疾患Principal Investigator

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"Brain-Mind" Stress and Atherosclerotic Disease: Mechanisms Unveiled through Lipid Metabolite AnalysisPrincipal Investigator

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Elucidation of bioactive lipid mediators related to ischemia-reperfusion injury and development of novel treatment strategyPrincipal Investigator

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Shinohara Masakazu 篠原正和

SHINOHARA Masakazu 篠原正和