NISHIO HISAHIDE 西尾久英

… Alternative Names

Researcher Number	80189258
Other IDs
Affiliation (Current)	2021: 神戸学院大学, 総合リハビリテーション学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 神戸学院大学, 総合リハビリテーション学部, 教授 2016 – 2017: 神戸大学, 医学研究科, 教授 2011 – 2015: 神戸大学, 医学(系)研究科(研究院), 教授 2013 – 2014: 神戸大学, 大学院医学研究科, 教授 2011 – 2012: 神戸大学, 大学院・医学研究科, 教授 … More
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Public health/Health science / Hygiene / Embryonic/Neonatal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Pediatrics / Hygiene / Hygiene / Eating habits, studies on eating habits / Public health/Health science
Keywords	Principal Investigator 脊髄性筋萎縮症 / SMN1遺伝子 / SMN2遺伝子 / プロモーター / スプライシング / spinal muscular atrophy / ジストロフィン / SMN蛋白 / カドミウム / subtractive suppressive hybridization … More Except Principal Investigator ジストロフィン / スプライシング / mRNA / 点突然変異 / メッセンジャーRNA / 神経芽腫 / 選択的スプライシング / がん幹細胞 / Rab / がん遺伝子 / 遺伝子異常 / Rab15 / 遺伝子欠失 / ADAMTS-1 / カドミウム / SNPs / ホメオボックス遺伝子 / MSUD / フィリピン / メープルシロップ尿症 / E2遺伝子 / G71R / Cd / ZNF265 / HOXB8 / BRCA1 / BRCA2 / RNA / レトロポゾン / 筋ジストロフィー / 遺伝子診断 / 神経線椎腫症1型 / NF1 / がん抑制遺伝子 / Duchenn型筋ジストロフィー / 神経線維腫症I型 / 蛋白合成 / In vitro翻訳 / 転写 / マイクロサテライト / 国際研究交流 / インド,インドネシア,スリランカ,オーストラリア,ブラジル,カナダ,スコットランド / 24 時間尿分析 / マグネシウム / タウリン / 食塩感受性 / 生活習慣病 / 脂質異常症 / 国際研究者交流 / インド（南、北）: 韓国 / 高血圧 / 24時間尿分析 / 食塩摂取 / マグネシウム摂取 / 栄養バイオマーカー / 24時間尿 / カロテノイド / インド / スリランカ / スコットランド / 遺伝子 / 肥満 / 栄養介入 / 24時間採尿 / 栄養のバイオマーカー / メタボリック症候群 / 高脂血症 / 糖尿病 / 遺伝子分析 / CARDIAC方式 / MTHFR / 遺伝子多型 / ホモシステイン / 葉酸 / アボリジニー / 爪遺伝子分析 / メリンジョ / 予後決定因子 / レチノイン酸 / 自然消退 / 細胞極性 / MRD / 微小残存病変 / spinal muscular atrophy / SMA / splicing / SMN2 / 微小残存病変(MRD) / 間葉系幹細胞(MSC) / ALDH / 楕円赤血球症 / 赤血球 / バンド3蛋白 / インドネシア / 遺伝性楕円赤血球症 / バンド3蛋白遺伝子 / Ovalocytosis / Erythrocyte / Band 3 protein / Deletion mutation / Indonesia / ジストロフィン神戸 / リンパ芽球 / アンチセンスオリゴヌクレオチド / エクソンスキッピング / エクソン / スキッピング / 遺伝子治療 / Duchenne型筋ジストロフィー / dystrophin Kobe / lymphoblastoid cells / antisenseoligonucleotide / exon skipping / ジストロフィン遺伝子 / 分子種 / 心筋 / dystrophin / isoform / alternative splicing / heart / 化学物質 / 紫外線 / クロロホルム / 遺伝子転写産物 / 内因性レトロウイルス関連遺伝子 / トリハロメタン / トロンボスポンジン / げっ歯類C型レトロウイルス / 発癌 / chemicals / ultraviolet ray / chloroform / endogenous murine leukemia virus / アルツハイマー病 / アルミニウム / トロンビン / ERAB蛋白 / Alzheimer's disease / aluminum / thrombin / ERAB / 内分泌攪乱物質 / マイクロフィジオメトリーアッセイ法 / MCF-7細胞 / β-エストラジオール / エストロゲン受容体(α型) / 内分泌撹乱物質 / M1WT3細胞 / carbachol / endocrine disruptor / Microphysiometer System / MCF-7 cell / β-estradiol / estrogen receptor α / cadmium / 前頭骨部篩骨部脳瘤 / 神経管欠損 / メチレンテトラヒドロ葉酸還元酵素 / 頭部形成 / 前頭骨部〓骨部脳瘤 / 疾患責任遺伝子 / 疾患感受性遺伝子 / 頭部形成ホメオボックス遺伝子 / Neural tube defect / Frontoethmoidal encephalocele / Neural tube defects / 5, 10-methylenetetrahydrofolate reductase / Homeobox genes / craniofacial formation / 新生児スクリーニング / gene mutation / neonatal screeing / Philippines / 新生児 / Philippine / maple syrup urine disease / E2 gene / neonate / 発がん性化学物質 / スプライシング関連因子 / 重金属 / Carcinogenic compound / Alternative splicing / Cadmium / Homeobox gene / Spliceosomal protein / 日本人 / 韓国人 / 乳がん / UGT1A1遺伝子 / -3279 T>G / UGT遺伝子 / Japanese / Korean / breast cancer / UGT1A1 gene / -3279T>G / スプライシング関連蛋白 / SMN遺伝子 / HOX遺伝子 / in vitroスプライシング / splicing related protein / SMN gene / HOX gene Less

Development of Newborn Screening System for Spinal Muscular AtrophyPrincipal Investigator
- Principal Investigator
  
  西尾久英
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kobe Gakuin University
New Treatment Strategy for SMA: In tron-retention of the SMN2 genePrincipal Investigator
- Principal Investigator
  
  Nishio Hisahide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe Gakuin University
  Kobe University
Targeting Rab family small G proteins as a novel neuroblastoma therapeutic approach
- Principal Investigator
  
  Nishimura Noriyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Drug treatment for spinal muscular atrophy activating signal transduction pathwaysPrincipal Investigator
- Principal Investigator
  
  Nishio Hisahide
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Development of spinal muscular atrophy treatment by SMN2 gene splicing modification
- Principal Investigator
  
  NAKAGAWA Taku
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Role of Rab family small G proteins in the development of neuroblastoma cancer stem cells
- Principal Investigator
  
  NISHIMURA Noriyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Establishment of treatment strategy for spinal muscular atrophybased on the SMN2gene transcription controlPrincipal Investigator
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Role of Rab family small G proteins in determining the prognosis of neuroblastoma patients
- Principal Investigator
  
  LEE Myeongjin
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Development of predictive-preventive nutritional science for metabolic syndrome in representative high-risk populations in the world
- Principal Investigator
  
  YAMORI Yukio
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Mukogawa Women's University
Research on splicing mechanism using a metal which disrupts splicing reaction
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation TechnologyPrincipal Investigator
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and Korean
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
Molecular epidemiolojial study on maple syrup urine disease in Philippine.
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Research on the effect of carcinogenic chemical compounds on alternative splicing
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Molecular epidemiology of neonatal Gilbert's syndrome in MalaysiaPrincipal Investigator
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kobe University
Development of a new treatment with splicing modulators for spinal muscular atrophyPrincipal Investigator
- Principal Investigator
  
  NSIHIO Hisahide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Molecular genetic study on maple syrup urine disease in Philippines
- Principal Investigator
  
  TAKESHIMA Yasuhiro, 中村肇
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Molecular genetic study of frontoethmoidal encephalocele in Indonesia
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University Graduate School of medicine
Screening system for chemicals attacking pre-mRNA splicing machinery in cellsPrincipal Investigator
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University Graduate School of medicine
Detection of endocrine disruptor effect using Microphysiometer System
- Principal Investigator
  
  LEE Myeong jin
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
アルツハイマー病アミロイド・ベーター蛋白の毒性発現の抑制機構(メタロチオネイン及びその類似蛋白とアルミニウムの影響)
- Principal Investigator
  
  SUMINO Kimiaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Molecular biological studies on environmental chemical pollutants interfering with endocrine systemsPrincipal Investigator
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
神経線維腫症1型遺伝子異常の蛋白発現ベクターを応用した診断法の確立
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
リンパ球特異的に発現するL-ジストロフィンの発現制御機構に関する研究Principal Investigator
- Principal Investigator
  
  西尾久英
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Molecular Biological Analysis of Cells and Tissues from Animals Exposed to Chemicals and Ultraviolet Rays
- Principal Investigator
  
  SUMINO Kimiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
神経線維種症1型遺伝子異常の蛋白発現ベクターを応用した診断法の確立
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Cloning and study on physiological role of new dystrophin isoform.
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
蛋白発現ベクターを応用した神経線椎腫症1型の遺伝子異常の解析
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
メッセンジャーRNAを標的としたジストロフィン異常の分子遺伝学的研究
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
ゲノム内分散性反復配列の挿入を認めたジストロフィン遺伝子転写開始領域の構造の研究Principal Investigator
- Principal Investigator
  
  西尾久英
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Molecular epidemiological study ovalocytosis in Indonesia
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kobe University
Molecular biological study to establish the treatment for Duchenne muscular dystrophy
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
MyoDの筋分化誘導作用を応用したジストロフィン異常の分子生物学的解析
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
メッセンジャーRNA前駆体2次構造の有するプライシング部位の制御機能
- Principal Investigator
  
  MATSUO Masafumi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
筋分化誘導因子を応用したジストロフィン異常の分子生物学的解析
- Principal Investigator
  
  松尾雅文
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University

[Book] 別冊　日本臨床　新領域別症候群シリーズNo.272014
- Author(s)
  西尾久英
- Total Pages
  903
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461549
[Book] 脊髄性筋萎縮症診療マニュアル2012
- Author(s)
  西尾久英
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Incidence of Infantile Spinal Muscular Atrophy on Shikoku Island of Japan2019
- Author(s)
  OKamoto K, Fukuda M, Nishio H, et al.
- Journal Title
  
  Brain and Development
  
  Volume: 41 Pages: 36-42
- DOI
  10.1016/j.braindev.2018.07.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] A Novel System for Spinal Muscular Atrophy Screening in Newborns: Japanese Pilot Study2019
- Author(s)
  Shinohara M, Niba ETE, Nishio H, et al.
- Journal Title
  
  International Journal of Neonatal Screening
  
  Volume: 5
- DOI
  10.3390/ijns5040041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Novel BICD2 mutation in a Japanese family with autosomal dominant lower extremity-predominant spinal muscular atrophy-22018
- Author(s)
  Yoshioka M, Morisada N, Toyoshima D, Yoshimura H, Nishio H, Iijima K, Takeshima Y, Uehara T, Kosaki K.
- Journal Title
  
  Brain and Development
  
  Volume: 40 Pages: 343-347
- DOI
  10.1016/j.braindev.2017.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077, KAKENHI-PROJECT-18K08243
[Journal Article] Receiver operating curve analyses of urinary titin of healthy 3-y-old children may be a noninvasive screening method for Duchenne muscular dystrophy2018
- Author(s)
  Matsuo M, Shirakawa T, Awano H, Nishio H.
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 486 Pages: 110-114
- DOI
  10.1016/j.cca.2018.07.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Intron-retained transcripts of the spinal muscular atrophy genes, SMN1 and SMN22018
- Author(s)
  Harahap NIF, Niba ETE, Ar Rochmah M, Wijaya YOS, Saito T, Saito K, Awano H, Morioka I, Iijima K, Lai PS, Matsuo M, Nishio H, Shinohara M.
- Journal Title
  
  Brain & Development
  
  Volume: 40 Pages: 670-677
- DOI
  10.1016/j.braindev.2018.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10077, KAKENHI-PROJECT-16K07216
[Journal Article] Spinal muscular atrophy carriers with two SMN1 copies2017
- Author(s)
  Ar Rochmah Mawaddah、Awano Hiroyuki、Awaya Tomonari、Harahap Nur Imma Fatimah、Morisada Naoya、Bouike Yoshihiro、Saito Toshio、Kubo Yuji、Saito Kayoko、Lai Poh San、Morioka Ichiro、Iijima Kazumoto、Nishio Hisahide、Shinohara Masakazu
- Journal Title
  
  Brain and Development
  
  Volume: 39 Pages: 851-860
- DOI
  10.1016/j.braindev.2017.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Genetic screening of spinal muscular atrophy using a real-time modified COP-PCR technique with dried blood-spot DNA2017
- Author(s)
  Ar Rochmah M, Harahap NIF, Niba ETE, Nakanishi K, Awano H, Morioka I, Iijima K, Saito T, Saito K, Lai PS, Takeshima Y, Takeuchi A, Bouike Y, Okamoto M, Nishio H, Shinohara M
- Journal Title
  
  Brain and Development
  
  Volume: 39(9) Pages: 774-782
- DOI
  10.1016/j.braindev.2017.04.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07216, KAKENHI-PROJECT-17K10077
[Journal Article] DMD transcripts in CRL-2061 rhabdomyosarcoma cells show high levels of intron retention by intron-specific PCR amplification2017
- Author(s)
  Niba ETE, Yamanaka R, Rani AQM, Awano H, Matsumoto M, Nishio H, Matsuo M
- Journal Title
  
  Cancer Cell International
  
  Volume: 17 Pages: 58-73
- DOI
  10.1186/s12935-017-0428-4
- NAID
  120006373783
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07216, KAKENHI-PROJECT-17K10077
[Journal Article] Cryptic splice activation but not exon skipping is observed in minigene assays of dystrophin c.9361+1G>A mutation identified by NGS2017
- Author(s)
  Emma Tabe Eko Niba
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 1-7 Pages: 531-537
- DOI
  10.1038/jhg.2016.162
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07216, KAKENHI-PROJECT-17K10077
[Journal Article] SMA mutations in SMN Tudor and C-terminal domains destabilize the protein2017
- Author(s)
  Takarada Toru、Ar Rochmah Mawaddah、Harahap Nur Imma Fatimah、Shinohara Masakazu、Saito Toshio、Saito Kayoko、Lai Poh San、Bouike Yoshihiro、Takeshima Yasuhiro、Awano Hiroyuki、Morioka Ichiro、Iijima Kazumoto、Nishio Hisahide、Takeuchi Atsuko
- Journal Title
  
  Brain and Development
  
  Volume: 39 Pages: 606-612
- DOI
  10.1016/j.braindev.2017.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10077
[Journal Article] Early detection of tumor relapse/regrowth by consecutive minimal residual disease monitoring in high-risk neuroblastoma patients2016
- Author(s)
  Hirase S, Saitoh A, Hartomo TB, Kozaki A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Yamamoto N, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
- Journal Title
  
  ONCOLOGY LETTERS
  
  Volume: 12 Pages: 1119-1123
- DOI
  10.3892/ol.2016.4682
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-16K19644
[Journal Article] Two Japanese patients with SMA type 1 suggest that axonal-SMN may not modify the disease severity.2015
- Author(s)
  Yamada H, Nishida Y, Maihara T, Sa'adah N, Harahap NI, Nurputra DK, Ar Rochmah M, Nishimura N, Saito T, Kubo Y, Saito K, Nishio H.
- Journal Title
  
  Pediatr Neurol.
  
  Volume: 52 Pages: 638-641
- DOI
  10.1016/j.pediatrneurol.2015.02.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma.2015
- Author(s)
  Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hasegawa D, Kosaka Y, Matsuo M, Hayakawa A, Takeshima Y, Iijima K, Nishio H, and Nishimura N.
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Pages: 1089-1098
- DOI
  10.3892/ijo.2014.2801
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-26860801, KAKENHI-PROJECT-26860802
[Journal Article] A Study of valproic acid for patients with spinal muscular atrophy.2015
- Author(s)
  Saito T, Nurputra DK, Harahap NI, Harahap IS, Yamamoto H, Muneshige E, Nisizono H, Matsumura T, Fujimura H, Sakoda S, Saito K, Nishio H.
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 3 Pages: 49-57
- DOI
  10.1111/ncn3.140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] A new method for SMN1 and hybrid SMN gene analysis in spinal muscular atrophy using long-range PCR followed by sequencing.2015
- Author(s)
  Kubo Y, Nishio H, Saito K
- Journal Title
  
  J Hum Genet
  
  Volume: 60 Pages: 233-239
- DOI
  10.1038/jhg.2015.16
- NAID
  40020462572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] A Rapid, Accurate and Simple Screening Method for Spinal Muscular Atrophy: High-Resolution Melting Analysis Using Dried Blood Spots on Filter Paper.2015
- Author(s)
  Sa'adah N, Harahap NI, Nurputra DK, Rochmah MA, Morikawa S, Nishimura N, Sadewa AH, Astuti I, Haryana SM, Saito T, Saito K, Nishio H.
- Journal Title
  
  Clin Lab.
  
  Volume: 61 Pages: 575-580
- DOI
  10.7754/clin.lab.2014.141008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Trinucleotide insertion in the SMN2 promoter may not be related to the clinical phenotype of SMA.2015
- Author(s)
  Harahap NI, Takeuchi A, Yusoff S, Tominaga K, Okinaga T, Kitai Y, Takarada T, Kubo Y, Saito K, Sa'adah N, Nurputra DK, Nishimura N, Saito T, Nishio H.
- Journal Title
  
  Brain Dev.
  
  Volume: 37 Pages: 669-676
- DOI
  10.1016/j.braindev.2014.10.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] SMA Screening System Using Dried Blood Spots on Filter Paper: Application of COP-PCR to the SMN1 Deletion Test.2015
- Author(s)
  Kato N, Sa'Adah N, Ar Rochmah M, Harahap NI, Nurputra DK, Sato H, Sadewa AH, Astuti I, Haryana SM, Saito T, Saito K, Nishimura N, Nishio H, Takeuchi A.
- Journal Title
  
  Kobe J Med Sci.
  
  Volume: 60
- NAID
  110009871896
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Salbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells.2015
- Author(s)
  Harahap NI, Nurputra DK, Rochmah MA, Shima A, Morisada N, Takarada T, Takeuchi A, Tohyama Y Yanagisawa S, Nishio H
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 4 Pages: 351-356
- DOI
  10.1016/j.bbrep.2015.10.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-25461549
[Journal Article] Differential expression of minimal residual disease markers in peripheral blood and bone marrow samples from high-risk neuroblastoma patients.2015
- Author(s)
  Yamamoto N, Kozaki A, Hartomo TB, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Hirase S, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
- Journal Title
  
  Oncol Let
  
  Volume: 10 Pages: 3228-3232
- DOI
  10.3892/ol.2015.3710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461584, KAKENHI-PROJECT-26860801, KAKENHI-PROJECT-26860802
[Journal Article] 脊髄性筋萎縮症　遺伝子診断から治療戦略まで2014
- Author(s)
  西尾久英
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 118 Pages: 1315-1323
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Intragenic mutations in SMN1 may contribute more significantly to clinical severity than SMN2 copy numbers in some spinal muscular atrophy (SMA) patients.2014
- Author(s)
  Yamamoto T, Sato H, Lai PS, Nurputra DK, Harahap NIF, Morikawa S, Nishimura N, Kurashige T, Tomohiko O, Nakajima H, Yamada H, Nishida Y, Toda S, Takanashi J, Takeuchi A, Tohyama Y, Kubo Y, Saito K, Takeshima Y, Matsuo M, Nishio H
- Journal Title
  
  Brain Dev.
  
  Volume: 未 Pages: 914-920
- DOI
  10.1016/j.braindev.2013.11.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591790, KAKENHI-PROJECT-25461549
[Journal Article] PLS3 expression and SMA phenotype: a commentary on correlation of PLS3 expression with disease severity in children with spinal muscular atrophy.2014
- Author(s)
  Nishio H.
- Journal Title
  
  J Hum Genet.
  
  Volume: 59 Pages: 64-65
- DOI
  10.1038/jhg.2013.124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Molecular pathology of Sandhoff disease with p.Arg505Gln in HEXB: application of simulation analysis.2013
- Author(s)
  Yasui N, Takaoka Y, Nishio H, Nurputra DK, Sekiguchi K, Hamaguchi H, Kowa H, Maeda E, Sugano A, Miura K, Sakaeda T, Kanda F, Toda T.
- Journal Title
  
  J Hum Genet.
  
  Volume: 58 Pages: 611-617
- DOI
  10.1038/jhg.2013.68
- NAID
  10031195298
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-25461549
[Journal Article] 劇症肝不全を発症した脊髄性筋萎縮症の1例2013
- Author(s)
  羽深理恵, 鈴木俊明, 長谷川博也, 唐澤環, 金子詩子, 池住洋平, 大橋伯, 赤坂紀幸, 遠山潤, 西尾久英, 齋藤昭彦
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 117 Pages: 1031-1036
- NAID
  10031184018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461549
[Journal Article] Spinal Muscular Atrophy: From Gene Discovery to Clinical Trials2013
- Author(s)
  Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SK, Low PS, Saito K, Nishio H
- Journal Title
  
  Annals of Human Genetics
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Spinal Muscular Atrophy: From Gene Discovery to Clinical Trials.2013
- Author(s)
  Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SK, Low PS, Saito K, Nishio H
- Journal Title
  
  Ann Hum Genet.
  
  Volume: 77 Pages: 435-463
- DOI
  10.1111/ahg.12031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-25461549, KAKENHI-PROJECT-25860860
[Journal Article] Minimal residual disease monitoring in neuroblastoma patients based on the expression of a set of real-time RT-PCR markers in tumor-initiating cells2013
- Author(s)
  Hartomo, T.B. et al.
- Journal Title
  
  Oncol. Rep
  
  Volume: 29 Pages: 1629-1636
- DOI
  10.3892/or.2013.2286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591540
[Journal Article] Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells2012
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Lee MJ, Yamamoto T, Morikawa S, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H
- Journal Title
  
  Environ. Health Prev. Med
  
  Volume: 17 Pages: 246-251
- NAID
  10030617244
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Rab15 alternative splicing is altered in spheres of neuroblastoma cells.2012
- Author(s)
  Pham, TVH.
- Journal Title
  
  Oncol. Rep
  
  Volume: (in press)(掲載確定) Pages: 2045-2049
- DOI
  10.3892/or.2012.1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591361, KAKENHI-PROJECT-23591540
[Journal Article] Valproic acid increases SMN2 expression and modulates SF2/ASF and hnRNPA1 expression in SMA fibroblast cell lines.2012
- Author(s)
  Harahap IS, Saito T, San LP, Sasaki N, Gunadi, Nurputra DK, Yusoff S, Yamamoto T, Morikawa S, Nishimura N, Lee MJ, Takeshima Y, Matsuo M, Nishio H
- Journal Title
  
  Brain Dev.
  
  Volume: 34 Pages: 213-222
- DOI
  10.1016/j.braindev.2011.04.010
- NAID
  10031050154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-23791175
[Journal Article] Acetaminophen administration in a patient with Gilbert's syndrome.2012
- Author(s)
  Nakagawa T
- Journal Title
  
  Pediatr Int
  
  Volume: 54 Pages: 934-6
- DOI
  10.1111/j.1442-200x.2012.03602.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-24791060
[Journal Article] Spinal muscular atrophy patient detection and carrier screening using dried blood spots on filter paper.2012
- Author(s)
  Harahap NI, Harahap IS, Kaszynski RH, Nurputra DK, Hartomo TB, Pham HT, Yamamoto T, Morikawa S, Nishimura N, Rusdi I, Widiastuti R, Nishio H.
- Journal Title
  
  Genet Test Mol Biomarkers
  
  Volume: 16 Pages: 123-129
- DOI
  10.1089/gtmb.2011.0109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-23791175
[Journal Article] Paramyotonia congenita: from clinical diagnosis to in silico protein modeling analysis.2012
- Author(s)
  Nurputra DK
- Journal Title
  
  Pediatr Int
  
  Volume: 54 Pages: 602-12
- DOI
  10.1111/j.1442-200x.2012.03646.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-24791060
[Journal Article] Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells.2012
- Author(s)
  Nishimura, N.
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: (in press)(掲載確定) Issue: 3 Pages: 246-251
- DOI
  10.1007/s12199-011-0239-5
- NAID
  10030617244
- ISSN
  1342-078X, 1347-4715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591361, KAKENHI-PROJECT-23591540
[Journal Article] Rab15 alternative splicing is altered in spheres of neuroblastoma cells2012
- Author(s)
  Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Ishida T, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H and Nishimura N
- Journal Title
  
  Oncol. Rep
  
  Volume: 27 Pages: 2045-2049
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Allele-specific PCR for a cost-effective & time- efficient diagnostic screening of spinal muscular atrophy2012
- Author(s)
  Marini M, Sasongko TH, Watihayati MS, Atif AB, Hayati F; Gunadi, Zabidi-Hussin ZA, Ravichandran M, Nishio H, Zilfalil BA
- Journal Title
  
  Indian J Med Res
  
  Volume: 135 Pages: 31-35
- DOI
  10.4103/0971-5916.93421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 小児医学最近の進歩脊髄性筋萎縮症と SMN 蛋白と低分子量リボ核蛋白合成2011
- Author(s)
  西尾久英, 斉藤利雄, 森川悟, 山本友人, Dian Kesumapramudya Nurputra, 寶田徹, 竹内敦子, 西村範行, 竹島泰弘, 松尾雅文
- Journal Title
  
  小児科
  
  Volume: 52 Pages: 1535-1542
- NAID
  40019029323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells2011
- Author(s)
  Nishimura N, Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Nishio H and Matsuo M
- Journal Title
  
  Oncol. Rep
  
  Volume: 26 Pages: 145-151
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Long-term stabilization of respiratory conditions in patients with spinal muscular atrophy type 2 by continuous positive airway pressure: a report of two cases2011
- Author(s)
  Katayama M, Naritomi H, Nishio H, Watanabe T, Teramoto S, Kanda F, Hazama A.
- Journal Title
  
  Kobe J Med Sci
  
  Volume: 57
- NAID
  120003659642
- URL
  http://www.lib.kobe-u.ac.jp/handle_kernel/81003741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 非侵襲的陽圧換気療法と器械による咳介助を活用し気管内挿管から離脱した脊髄性筋萎縮症I型2011
- Author(s)
  粟野宏之, 李知子, 八木麻理子, 竹島泰弘, 西尾久英, 松尾雅文
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 115 Pages: 1451-1455
- NAID
  10029704933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 小児医学最近の進歩脊髄性筋萎縮症とSMN蛋白と低分子量リボ核蛋白合成2011
- Author(s)
  西尾久英, 斉藤利雄, 森川悟, 山本友人, Dian Kesumapramudya Nurputra, 實田徹, 竹内敦子, 西村範行, 竹島泰弘, 松尾雅文
- Journal Title
  
  小児科
  
  Volume: 52 Pages: 1535-1542
- NAID
  40019029323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Diagnosis of spinal muscular atrophy via high-resolution melting analysis symmetric polymerase chain reaction without probe: a screening evaluation for SMN1 deletions and intragenic mutations.2011
- Author(s)
  Morikawa S, Harahap IS, Kaszynski RH, Yamamoto T, Pramudya DK, Van Pham HT, Hartomo TB, Lee MJ, Morioka I, Nishimura N, Yokoyama N, Ueno Y, Matsuo M, Nishio H.
- Journal Title
  
  Genet Test Mol Biomarkers
  
  Volume: 15 Pages: 677-684
- DOI
  10.1089/gtmb.2010.0237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-23791175
[Journal Article] 非侵襲的陽圧換気療法と器械による咳介助を活用し気管内挿管から離脱した脊髄性筋萎縮症 I型.2011
- Author(s)
  粟野宏之, 李知子, 八木麻理子, 竹島泰弘,西尾久英, 松尾雅文
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 115 Pages: 1451-1455
- NAID
  10029704933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Long-term stabilization of respiratory conditions in patients with spinalmuscular atrophy type 2 by continuous positive airway pressure : a report of two cases2011
- Author(s)
  Katayama M, Naritomi H, Nishio H, Watanabe T, Teramoto S, Kanda F, Hazama A
- Journal Title
  
  Kobe J Med Sci
  
  Volume: 57
- NAID
  120003659642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells.2011
- Author(s)
  Nishimura, N.
- Journal Title
  
  Oncol. Rep.
  
  Volume: 26 Pages: 145-151
- DOI
  10.3892/or.2011.1255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591361, KAKENHI-PROJECT-23591540
[Journal Article] Novel SCN1A mutations in Indonesian patients with severe myoclonic epilepsy in infancy.2010
- Author(s)
  Herini ES, Gunadi, van Kempen MJ, Yusoff S, Sutaryo, Sunartini, Patria SY, Matsuo M, Lindhout D, Nishio H
- Journal Title
  
  Pediatr Int.
  
  Volume: 52 Pages: 234-239
- NAID
  10028181879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 小児医学最近の進歩脊髄性筋萎縮症 up to date 遺伝子診断2010
- Author(s)
  西尾久英, 西村範行, 森川悟, 山本友人, 松尾雅文
- Journal Title
  
  小児科
  
  Volume: 51 Pages: 1535-1542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Screening of the LIX1 gene in Japanese and Malaysian patients with SMA and/or SMA-like disorder.2010
- Author(s)
  Sasongko TH, Gunadi, Yusoff S, Atif AB, Fatemeh H, Rani A, Marini M, Aziz CB, Zabidi-Hussin Z, Nishio H, Zilfalil BA
- Journal Title
  
  Brain Dev.
  
  Volume: 32 Pages: 385-389
- DOI
  10.1016/j.braindev.2009.06.008
- NAID
  10027491401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 小児医学最近の進歩脊髄性筋萎縮症 up to date 治療戦略2010
- Author(s)
  西尾久英, HarahapIndra Sari Kusuma, 斉藤利雄, 西村範行, 森川悟, 山本友人, 中川卓, 竹島泰弘, 松尾雅文
- Journal Title
  
  小児科
  
  Volume: 51 Pages: 1535-1542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Generalized epilepsy with febrile seizures plus (GEFS+)spectrum : clinical manifestations and SCN1A mutations in Indonesian patients.2010
- Author(s)
  Herini ES, Gunadi, Harahap IS, Yusoff S, Morikawa S, Patria SY, Nishimura N, Sunartini, Sutaryo, Takada S, Matsuo M, Nishio H
- Journal Title
  
  EpilepsyRes.
  
  Volume: 90 Pages: 132-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] A polymorphic mutation, c.-32791>G, in the UGT1A1 promoter is a risk factor for neonatal jaundice in the Malay population.2010
- Author(s)
  Yusoff S, Takeuchi A, Ashi C, Tsukada M, Ma'amor NH, Alwi Zilfalil B, Mohd Yusoff N, Nakamura T, Hirai M, Harahap ISK, Gunadi, Lee MJ, Takaoka Y, Nishimura N, Morikawa S, Morioka I, Yokoyama N, Matsuo M, Nishio H, van Rostenberghe H.
- Journal Title
  
  Pediatr Res.
  
  Volume: 67 Pages: 401-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] 小児医学最近の進歩脊髄性筋萎縮症 up to date 医学的管理2010
- Author(s)
  西尾久英, 斉藤利雄, 西村範行, 森川悟, 山本友人, 三宅理, 粟野宏之, 竹島泰弘, 松尾雅文
- Journal Title
  
  小児科
  
  Volume: 51 Pages: 1797-1806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127
[Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure2008
- Author(s)
  Gunadi, Sasongko, TH, Yusoff, S, Lee, MJ, Nishioka, E, Matsuo, M, Nishio, H
- Journal Title
  
  Ann Hum Genet 72(2)
  
  Pages: 288-291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure.2008
- Author(s)
  Gunadi, Sasongko TH, Yusoff S, Lee MJ, Nishioka E, matsuo M, Nishio H.
- Journal Title
  
  Ann Hum Genet. 72
  
  Pages: 288-291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] SMN2 and NAP gene dosages in Vietnamese patients with spinal muscular atrophy2008
- Author(s)
  Van, Khanh, TV, Teguh, Haryo, Sasongko, Dang, Diem Hong , Nguyen, Thi, Hoan, Vu, Chi, Dung, Myeongn Jin Lee , Gunadi, Indra, Sari, Kusuma, Harahap, Yasuhiro, Takeshima, Masafumi, Matsuo, Hisahide, Nishio
- Journal Title
  
  Pediatr Int (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] SMN2 and NAIP gene dosages in Vietnamese patients with spinal muscular atrophy.2008
- Author(s)
  Van Khanh TV, Teguh Haryo Sasongko, Dang Diem Hong, Nguyen Thi Hoan, Vu Chi Dung, Myeong Jin Lee, Gunadi, Indra Sari Kusumma Harahap, Yasuhiro Takeshima, Masafumi Matsuo and Hisahide Nishio.
- Journal Title
  
  Pediatrics International (in press)
- NAID
  10025343726
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Deletion analyses of SMN1 and NAIP genes in Malaysian spinal muscular atrophy patients.2007
- Author(s)
  Watihayati MS, Zabidi-Hussin AM, Tang TH, Matsuo M, Nishio H, Zilfalil BA.
- Journal Title
  
  Pediatr Int. 49
  
  Pages: 11-4
- NAID
  10018837439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] C117T variant in the SMN1 gene found in the Japanese population2007
- Author(s)
  Sadewa, AH, Harada, Y, Sasongko, TH, Matsuo, M, Nishio, H
- Journal Title
  
  Pediatr Int 49(1)
  
  Pages: 8-10
- NAID
  10018837429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007
- Author(s)
  Kotani, T, Sutomo, R, Sasongko, TH, Sadewa, AH, Gunadi, Minato, T,Fujii, E, Endo, S, Lee, MJ, Ayaki, H, Harada, Y, Matsuo, M, Nishio, H
- Journal Title
  
  J Neurol 254(5)
  
  Pages: 624-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Zilfalil B. A. NAIP-Deletion Analysis in Malaysian Patients with Spinal Muscular Atrophy.2007
- Author(s)
  Watihayati M.S., Zabidi-Hussin A. M. H., Tang T. H., Nishio H.,
- Journal Title
  
  Kobe J Med Sci. 53
  
  Pages: 171-175
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] NAIP-Deletion Analysis in Malaysian Patients with Spinal Muscular Atrophy2007
- Author(s)
  Watihayati, M.S., Zabidi-Hussin, A.M.H., Tang, T.H., Nishio, H., Zilfalil, B.A
- Journal Title
  
  Kobe J Med Sci 53(4)
  
  Pages: 171-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Deletion analyses of SMN1 and NAP genesin Malaysian spinal muscular atrophy patients2007
- Author(s)
  Watihayati, MS, Zabidi-Hussin, AM, Tang, TH, Matsuo, M, Nishio, H, Zilfalil, BA
- Journal Title
  
  Pediatr Int 49(1)
  
  Pages: 11-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Zilfalil BA. Deletion analyses of SMN1 and NAIP genes in Malaysian spinal muscular atrophy patients.2007
- Author(s)
  Watihayati MS, Zabidi-Hussin AM, Tang TH, Matsuo M, Nishio H.
- Journal Title
  
  Pediatr Int. 49
  
  Pages: 303-303
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 80
  
  Pages: 624-630
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] C117T variant in the SMN1 gene found in the Japanese population.2007
- Author(s)
  Sadewa AH, Harada Y, Sasongko TH, Matsuo M, Nishio H.
- Journal Title
  
  Pediatr Int. 49
  
  Pages: 8-10
- NAID
  10018837429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 254
  
  Pages: 624-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] C117T variant in the SMN1 gene found in the Japanese population.2007
- Author(s)
  Sadcwa AH, Harada Y, Sasongko TH, Matsuuo M, Nishio H.
- Journal Title
  
  Pediatr Int. 254
  
  Pages: 8-10
- NAID
  10018837429
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006
- Author(s)
  Lee MJ, Ayaki H, Goji J, Kitamura K, Nishio
- Journal Title
  
  Arch Toxicol. 80
  
  Pages: 638-643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006
- Author(s)
  Lee, MJ, Ayaki, H, Goji, J, Kitamura, K, Nishio, H
- Journal Title
  
  Arch Toxicol 80(10)
  
  Pages: 638-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium exposure induces expression of the HOXB8 gene in COS-7 cells
- Author(s)
  Kanako, Nakagawa, Myeong, Jin Lee, Naokom Sasaki, Chiyo, Hayashi, Hisahide, Nishio
- Journal Title
  
  Toxicology in Vitro (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590556
[Patent] SNP検出方法2017
- Inventor(s)
  西尾久英、篠原正和
- Industrial Property Rights Holder
  西尾久英、篠原正和
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-196967
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] 脊髄性筋萎縮症スクリーニング・パイロット・スタディ2019
- Author(s)
  西尾久英
- Organizer
  第46回日本マススクリーニング学会
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] 脊髄性筋萎縮症の新生児マススクリーニング2018
- Author(s)
  西尾久英
- Organizer
  第121回日本小児科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] SMNハイブリッド遺伝子を有する脊髄性筋萎縮症2/3型の一例2018
- Author(s)
  杉本真里、佐久間肇、相場佳織、戸田泰子、横地健治、西尾久英
- Organizer
  第60回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] Genetic diagnosis of spinal muscular atrophy in Japan2017
- Author(s)
  Hisahide Nishio
- Organizer
  14th Asian and Oceanian Congress of Child Neurology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] Dystrophin Dp427 is lost due to multiple DMD intron retentions in rhabdomyosarcoma CRL-2061 cells.2017
- Author(s)
  Emma Niba, Ryo Yamanaka, Abdul Qawee Mahyoob Rani, Hiroyuki Awano, Masaaki Matsumoto, Hisahide Nishio, Masafumi Matsuo
- Organizer
  22nd INTERNATIONAL CONGRESS OF THE WORLD MUSCLE SOCIETY
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] Multi-intron retentions in DMD transcripts in CRL-2061 rhabdomyosarcoma cells identified by intron-specific RT-PCR2017
- Author(s)
  Emma Niba, Ryo Yamanaka, Rani Adbul, Hiroyuki Awano, Masaaki Matsumoto, Hisahide Nishio, Masafumi Matsuo.
- Organizer
  The 62nd Annual Meeting of the Japan Society of Human Genetics
- Data Source
  KAKENHI-PROJECT-17K10077
[Presentation] Sulbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells.2016
- Author(s)
  Harahap NI, Nurputra DK, Ar Rochmah M, Shima A, Morisada N, Takarada T, Takeuchi A, Tohyama Y, Yanagisawa Y, Nishio H.
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  京都, 国立京都国際会館
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] DENN domain protein DENND2A regulates the progression of neuroblastoma.2016
- Author(s)
  Yamamoto N, Thwin KK, Fujimura J, Nakanishi K, Mori T, Hayakawa A, Nishio H, Matsuo M, Hasegawa D, Kawasaki K, Kosaka Y, Iijima K, and Nishimura N.
- Organizer
  Advances in Neuroblastoma Research Conference 2016
- Place of Presentation
  Cairns, Australia
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] 神経芽腫患者の微小残存病変モニタリング2016
- Author(s)
  西村範行, Khin Kyaemon Thwin, 山本暢之, 森健, 早川晶, 長谷川大一郎, 川崎圭一郎, 小阪嘉之, 西尾久英, 飯島一誠.
- Organizer
  第119回日本小児科学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] Rab6B mediates the progression of neuroblastoma through the interaction with MTMR5.2016
- Author(s)
  Nishimura N, Pham TVH, Thwin KK, Yamamoto N, Mori T, Hayakawa A, Nishio H, Matsuo M, Hasegawa D, Kawasaki K, Kosaka Y, and Iijima K.
- Organizer
  Advances in Neuroblastoma Research Conference 2016
- Place of Presentation
  Cairns, Australia
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] Gender effects on the severity of spinal muscular atrophy (SMA) in 286 Japanese patients diagnosed in 1996-2015.2016
- Author(s)
  Shima A, Ar Rochmah M, Morisada N, Yanagisawa Y, Harahap NI, Saito T, Umeno Aiko, Kaneko K, Saito K, Iijima K, Nishio H
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  京都, 国立京都国際会館
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] HDAC6, a new candidate for therapeutic target of Spinal Muscular Atrophy (SMA)2015
- Author(s)
  Dian K Nurputra, Morita H, Harahap NI, Rochmah MA, Tohyama Y, Nishio H.
- Organizer
  The 11th Asian Society for Pediatric Research
- Place of Presentation
  大阪, グランキューブ大阪
- Year and Date
  2015-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Two high-risk neuroblastoma cases with early detection of tumor relapse/re-growth by consecutive minimal residual disease monitoring.2015
- Author(s)
  Saito A, Hirase S, Kozaki A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
- Organizer
  11th Asian Society for Pediatric Research
- Place of Presentation
  大阪
- Year and Date
  2015-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] Neuroblastoma minimal residual disease markers are differentially expressed in peripheral blood and bone marrow samples.2015
- Author(s)
  Uemura S, Yamamoto N, Kozaki A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
- Organizer
  11th Asian Society for Pediatric Research
- Place of Presentation
  大阪
- Year and Date
  2015-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] 小児期発症脊髄性筋萎縮症に対するバルプロ酸ナトリウム多施設共同医師主導治験2015
- Author(s)
  斎藤加代子, 荒川玲子, 齊藤利雄, 西尾久英
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  大阪, 帝国ホテル
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] 脊髄性筋萎縮症の重症度を規定する因子についての検討2015
- Author(s)
  森貞直哉, 島亜衣, Mawaddah Ar Rochmah, 叶明娟, 飯島一誠, 西尾久英
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  東京, 京王プラザホテル
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Differential expression of minimal residual disease markers in peripheral blood and bone marrow samples from high-risk neuroblastoma patients.2015
- Author(s)
  Uemura S, Yamamoto N, Kozaki A, Nino N, Takafuji S, Yokoi T, Saito A, Ishida T, Hasegawa D, Kawasaki K, Kosaka Y, Mori T, Hayakawa A, Iijima K, Nishio H, and Nishimura N.
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  山梨
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] SMN is essential for the HDAC6 mediated tubulin-deacetylation in fibroblasts.2014
- Author(s)
  Nurputra DK， Morita H， Nishio H， Tohyama Y.
- Organizer
  第61回日本生化学会近畿支部例会
- Place of Presentation
  京都市, 京都産業大学
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Induction of ALDH1A2 expression is critical for cancer stem cell properties in neuroblastoma2014
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, and Nishio H.
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 分裂酵母モデル系を用いた脊髄性筋萎縮症の原因タンパク質Smn1の機能解明2013
- Author(s)
  西島数人, 加藤俊明, 馬艶, 西尾久英
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都、京都ガーデンパレス
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] 神経筋疾患とIGF-1: 脊髄性筋萎縮症治療法の確立に向けて。2013
- Author(s)
  西尾久英
- Organizer
  第47回兵庫内分泌研究会
- Place of Presentation
  神戸市、神戸ポートピアホテル
- Invited
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Identification of ALDH1A2 as a critical ALDH isoform in neuroblastoma cells with cancer stem cell phenotype2013
- Author(s)
  Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, Nishio H, and Nishimura N.
- Organizer
  AACR Special Conference : Pediatric Cancer at the Crossroads
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 軽症で経過しているSMN1遺伝子新規点変異(c.5C>T)を認めたspinal muscular atrophy type IIIの16歳男性例2013
- Author(s)
  中森正博, 大下智彦, 倉重毅志, 上野弘貴, 越智一秀, 丸山博文, 西尾久英, 松本昌泰
- Organizer
  第94回日本神経学会中国・四国地方会
- Place of Presentation
  松山市、松山市総合コミュニティセンター
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Abnormal acetylation status of α-tubulin in fibroblasts derived from SMA patients.2013
- Author(s)
  Nurputra DK, Morita H, Nishio H, Tohyama Y.
- Organizer
  第60回日本生化学会近畿支部例会
- Place of Presentation
  吹田市、大阪大学　吹田キャンパス
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] 臨床的に脊髄性筋萎縮症と診断された患者の SMN 遺伝子解析2012
- Author(s)
  西尾久英, 西村範行, 森川悟, 山本友人, ディアン・ヌルプトラ, 中川卓, 竹島泰弘, 飯島一誠, 松尾雅文, 齊藤利雄
- Organizer
  第82回日本衛生学会総会
- Place of Presentation
  京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] Minimal residual disease monitoring in neuroblastoma patients by a set of real-time RT-PCR markers.2012
- Author(s)
  Tanaka A, Hasegawa D, Hartomo TB, Ishida T, Kawasaki K, Kosaka Y, Iijima K, Matsuo M, Nishio H, and Nishimura N.
- Organizer
  Advances in Neuroblastoma Research Conference 2012
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] Salbutamol modulates SMN2 expression in SMA fibroblast2012
- Author(s)
  Harahap Imma, Nurputra Dian、山本友人、森川悟、西村範行、西尾久英.
- Organizer
  第57回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] SMN2 遺伝子量解析による予測よりも軽症の経過をとった脊髄性筋萎縮症患者に対するプロモーター解析.2012
- Author(s)
  森川悟, 中川卓, 富永康仁, 沖永剛志, 西村範行, 竹島泰弘, 松尾雅文, 西尾久英
- Organizer
  第54回日本小児神経学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 脊髄性筋萎縮症の心機能異常2012
- Author(s)
  齊藤利雄, 西尾久英, 松村剛.
- Organizer
  第54回日本小児神経学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 茶カテキンの神経芽腫がん幹細胞に対する抗がん作用の検討2012
- Author(s)
  西村範行, Tri Budi Hartomo,李明鎭,長谷川大一郎,小阪嘉之,早川晶,竹島泰弘,飯島一誠,松尾雅文,西尾久英
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 脊髄性筋萎縮症に対するバルプロ酸投与.2012
- Author(s)
  齋藤利雄、Dian K Nurputra、Imma Harahap、森川悟、山本友人、西尾久英
- Organizer
  第57回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 脊髄性筋萎縮症患者の SMN プロモーター領域における転写活性2012
- Author(s)
  寳田徹, 近江昇一, 竹内敦子, Kesuma PramudyaNurputra Dian, 森川悟, 西尾久英.
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] Rab15 alternative splicing correlates with differentiation of neuroblastoma cells.2012
- Author(s)
  Hartomo TB, Pham TVH, Hasegawa D, Kosaka Y, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H, and Nishimura N.
- Organizer
  Advances in Neuroblastoma Research Conference 2012
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 神経芽腫症例におけるmultiple real-time RT-PCR markerを用いた微小残存病変(MRD)解析2012
- Author(s)
  田中愛子,長谷川大一郎, Tri Budi Hartomo,山本暢之,宮田憲二,越智聡史,斎藤敦郎,山下達也,石田敏章,川崎圭一郎,松尾雅文, Thi Van Huyen Pham,大橋浩基,森健,矢内友子,早川晶,竹島泰弘,小阪嘉之,飯島一誠,西尾久英,西村範行
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜(口演)
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 茶カテキンの神経芽腫がん幹細胞に対する抗がん作用の検討2012
- Author(s)
  西村範行, Tri Budi Hartomo, 李明鎭, 長谷川大一郎, 小阪嘉之,早川晶, 竹島泰弘, 飯島一誠, 松尾雅文, 西尾久英
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591540
[Presentation] 臨床的に脊髄性筋萎縮症と診断された患者のSMN遺伝子解析2012
- Author(s)
  西尾久英, 西村範行, 森川悟, 山本友人, ディアンヌルプトラ, 中川卓, 竹島泰弘, 飯島一誠, 松尾雅文, 齊藤利雄
- Organizer
  第82回日本衛生学会総会
- Place of Presentation
  京都大学吉田キャンパス(京都)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 歩行可能まで発達したが以後急速に運動機能の低下を認めた脊髄性筋萎縮症の1例2011
- Author(s)
  戸田壮一郎, 湯浅正太, 高梨潤一, 田邉雄三, 西尾久英
- Organizer
  第53日本小児神経学会総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 歩行可能まで発達したが以後急速に運動機能の低下を認めた脊髄性筋萎縮症の 1 例2011
- Author(s)
  戸田壮一郎, 湯浅正太, 高梨潤一, 田邉雄三, 西尾久英
- Organizer
  第53 日本小児神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 非侵襲的陽圧換気療法と器械による咳介助で呼吸ケアをおこなっている脊髄性筋萎縮症1 型の1例2010
- Author(s)
  粟野宏之, 李知子, 八木麻理子, 竹島泰弘, 西尾久英, 松尾雅文
- Organizer
  第43回日本小児呼吸器疾患学会
- Place of Presentation
  福岡
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] SMN1 遺伝子の片側アレルの欠失を認め、もう一方のアレルに点突然変異を認めた脊髄性筋萎縮症の1 例2010
- Author(s)
  森川悟, 山本友人,西村範行, 西尾久英, 竹島泰弘, 松尾雅文
- Organizer
  第250回日本小児科学会兵庫県地方会総会
- Place of Presentation
  神戸
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] 非侵襲的陽圧換気療法でよりよい QOL を維持できている脊髄性筋萎縮症 1 型の 1 例.2010
- Author(s)
  粟野宏之, 李知子, 八木麻理子, 竹島泰弘, 西尾久英, 松尾雅文.
- Organizer
  第251回日本小児科学会兵庫県地方会
- Place of Presentation
  姫路
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22591127
[Presentation] Genetics of Spinal Muscular Atrophy2008
- Author(s)
  Nishio, H
- Organizer
  The Joint 7th Human Genome Organization Pacific meeting and the 8th Asia-Pacific Conference on Human Genetics
- Place of Presentation
  Cebu-City, Philippines
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] SMN2遺伝子が3コピーあった脊髄性筋萎縮症3型の2歳女児例2007
- Author(s)
  梶本まどか, 末永尚子, 市山高志, 古川漸, 西野一三, 西尾久英
- Organizer
  第49回日本小児神経学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins.2006
- Author(s)
  Nishio H, Lee MJ, Kotani T, Sutomo R, interaction with target proteins. Nishio H, Lee MJ, Kotani T, Sutomo R, Sadewa AH, Sasongko TH, Gunadi, Matsuo M.
- Organizer
  The American Society of Human Genetics 56th Annual Meeting,
- Place of Presentation
  New Orleans
- Year and Date
  2006-11-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] 先天性白内障を合併した脊髄性筋萎縮症の男児例(会議録/症例報告)2006
- Author(s)
  牧野泰子, 村田水紀, 幸脇正典, 小山典久, 横地健治, 今井一徳, 河辺義和, 西尾久英, 西野一三
- Organizer
  第25回日本小児神経学会東海地方会
- Place of Presentation
  名古屋
- Year and Date
  2006-07-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins2006
- Author(s)
  Nishio, H, Lee, MJ, Kotani, T, Sutomo, R, Sadewa, AH, Sasongko, TH, Gunadi
- Organizer
  The American Society of Human Genetics 56th Annual Meeting
- Place of Presentation
  New Orleans, Louisiana
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] 神経芽腫がん幹細胞の発生・分化における細胞内小胞輸送の制御因子Rab6Bの役割.
- Author(s)
  西村範行, Thi Van Huyen Pham, Tri Budi Hartomo, 山本暢之, 平瀬敏志, 早川晶, 矢内友子, 長谷川大一郎, 川崎圭一郎, 小阪嘉之, 松尾雅文, 飯島一誠, 西尾久英.
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] Induction of ALDH1A2 expression is critical for cancer stem cell properties in neuroblastoma.
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, and Nishio H.
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] 脊髄性筋萎縮症におけるSMN1、SMN2、NAIP、GTF2H2、SERF1遺伝子解析
- Author(s)
  野口依子, 中町祐司, 林伸英, 河野誠司, 中川卓, 西尾久英
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡市, 福岡国際会議場
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] SMN1遺伝子exon6にframeshift変異を認めた脊髄性筋萎縮症1型の一例
- Author(s)
  山田博之, 西田吉伸, 松本貴子, 毎原敏郎, 山本友人, 西尾久英
- Organizer
  第56回小児神経学会総会
- Place of Presentation
  浜松市, アクトシティ浜松
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Aldehyde dehydrogenase 1A2 expression correlates with cancer stem cell properties in neuroblastoma.
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Takeshima Y, Iijima K, and Nishio H.
- Organizer
  Advances in Neuroblastoma Research Conference 2014
- Place of Presentation
  Cologne, Germany
- Year and Date
  2014-05-13 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-26461584
[Presentation] HDAC6, a new therapeutic target of SMA, work in the downstream pathway of cytoskeleton dynamics.
- Author(s)
  Nurputra DK， Morita H，Tohyama Y, Nishio H.
- Organizer
  日本人類遺伝学会第59回大会
- Place of Presentation
  東京都, タワーホール船堀
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25461549
[Presentation] Aldehyde dehydrogenase ALDH1A2 regulates cancer stem cell properties in neuroblastoma.
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Yamamoto N, Hirase S, Hayakawa A, Yanai T, Hasegawa D, Kawasaki K, Kosaka Y, Matsuo M, Iijima K, Nishio H.
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-26461584

1. MATSUO Masafumi (10157266)

# of Collaborated Projects: 18 results

# of Collaborated Products: 1 results
2. LEE Myeongjin (20273766)

# of Collaborated Projects: 12 results

# of Collaborated Products: 15 results
3. TAKESHIMA Yasuhiro (40281141)

# of Collaborated Projects: 10 results

# of Collaborated Products: 16 results
4. AYAKI Hitoshi (80222701)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
5. SUMINO Kimiaki (90030832)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. NISHIMURA Noriyuki (00322719)

# of Collaborated Projects: 5 results

# of Collaborated Products: 49 results
7. SHIRAKAWA Taku (30171044)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. NISHIYAMA Kaoru (00150061)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. HAYAKAWA Akira (40379376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
10. SEOATOMADJI

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. YAMORI Yukio (80025600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ICHIKAWA Atsushi (10025695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KINOSHITA Kenji (70441219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MORI Mari (70399343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KATO Norihiro (80293934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KATSUYA Tomohiro (30311757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAMADA Atsumi (40541967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAGUCHI Takashi (50449005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. BABA Takako (50643293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAGAWA Taku (40457073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. MORIKAWA Satoru (50457074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
22. ISHIDA Takafumi (20184533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OHASHI Tanaki (60362779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YOKOYAMA Naoki (20314487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KOSAKI Kenjiro (30234743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 中村肇 (40030978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 野津寛大 (70362796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 森沢猛 (30379375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 西本啓介 (00362773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 篠原正和 (80437483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
31. SUMADIONO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. ABDUL Sofro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. ハルヂオノ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. アブヅルソフロ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. MORISADA Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. Kosaka Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
37. AWANO HIROYUKI

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. Mori Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. Yanai Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 山本暢之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. 平瀬敏志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 戸田達史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 高梨潤一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 通山由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

NISHIO HISAHIDE 西尾 久英

NISHIO Hisahide 西尾 久英

NISHIO Hiashide 西尾 久英

Research Projects

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Development of Newborn Screening System for Spinal Muscular AtrophyPrincipal Investigator

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New Treatment Strategy for SMA: In tron-retention of the SMN2 genePrincipal Investigator

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Drug treatment for spinal muscular atrophy activating signal transduction pathwaysPrincipal Investigator

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Establishment of treatment strategy for spinal muscular atrophybased on the SMN2gene transcription controlPrincipal Investigator

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Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation TechnologyPrincipal Investigator

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NISHIO HISAHIDE 西尾久英

NISHIO Hisahide 西尾久英

NISHIO Hiashide 西尾久英