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Re Myeong  李 明鎭

ORCIDConnect your ORCID iD *help
… Alternative Names

LEE Myeongjin  李 明鎭

李 明鎮  リ ミヨンジン

李 明鎭  リ ミヨンジン

LEE Myeong Jin  李 明鎮

LEE Miyojin  李 明鎮

LIEE Jin  李 明鎮

LEE Myeong jin  李 明鎮

LEE Myeong jim  李 明鎭

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Researcher Number 20273766
Other IDs
Affiliation (Current) 2022: 大手前大学, 健康栄養学部, 教授
Affiliation (based on the past Project Information) *help 2011: 神戸大学, 大学院・医学研究科, 非常勤講師
2009 – 2011: Kobe University, 医学研究科, 非常勤講師
2007: Kobe University, Graduate School of Medicine, Assistant professor
2007: Kobe University, Graduate School of Medicine, Assistant professor
2005 – 2007: Kobe University, Graduate School of Medicine, Assistant professor, 医学系研究科, 講師 … More
2006: Kobe University, Graduate School of Medicine, Assistant professor, 大学院医学系研究科, 講師
2002 – 2004: Kobe University Graduate School of medicine Lecturer, 大学院・医学系研究科, 講師
2002: 神戸大学, 医学系研究科, 講師
2001: 神戸大学, 大学院・医学系研究科, 助手
1996 – 2000: 神戸大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Hygiene / Public health/Health science / Pediatrics / Hygiene / Public health/Health science
Except Principal Investigator
Hygiene / Pediatrics / Pediatrics / Public health/Health science
Keywords
Principal Investigator
日本人 / 韓国人 / 選択的スプライシング / カドミウム / G71R / Cd / ZNF265 / HOXB8 / BRCA1 / BRCA2 … More / 東アジア / メチレンテトラヒドロ葉酸還元酵素 / 遺伝子変異 / Hardy-Weinberg equilibrium / 神経芽腫 / 予後決定因子 / Rab15 / レチノイン酸 / がん幹細胞 / 自然消退 / Rab / 細胞極性 / 内分泌攪乱物質 / マイクロフィジオメトリーアッセイ法 / MCF-7細胞 / β-エストラジオール / エストロゲン受容体(α型) / 内分泌撹乱物質 / M1WT3細胞 / carbachol / endocrine disruptor / Microphysiometer System / MCF-7 cell / β-estradiol / estrogen receptor α / cadmium / 発がん性化学物質 / ホメオボックス遺伝子 / スプライシング関連因子 / 重金属 / Carcinogenic compound / Alternative splicing / Cadmium / Homeobox gene / Spliceosomal protein / 乳がん / UGT1A1遺伝子 / -3279 T>G / UGT遺伝子 / Japanese / Korean / breast cancer / UGT1A1 gene / -3279T>G / スプライシング関連蛋白 / SMN遺伝子 / HOX遺伝子 / in vitroスプライシング / splicing related protein / SMN gene / HOX gene … More
Except Principal Investigator
脊髄性筋萎縮症 / spinal muscular atrophy / ADAMTS-1 / カドミウム / subtractive suppressive hybridization / cadmium / スプライシング / SMN1遺伝子 / SMN2遺伝子 / hnRNP C1 / C2 / ペプチド核酸 / the SMN1 gene / the SMN2 gene / ジストロフィン / リンパ球 / プロモーター / 化学物質 / 紫外線 / クロロホルム / 遺伝子転写産物 / 内因性レトロウイルス関連遺伝子 / トリハロメタン / トロンボスポンジン / げっ歯類C型レトロウイルス / 発癌 / chemicals / ultraviolet ray / chloroform / mRNA / endogenous murine leukemia virus / アルツハイマー病 / アルミニウム / トロンビン / ERAB蛋白 / Alzheimer's disease / aluminum / thrombin / ERAB / 内分泌撹乱物質 / Subtractive suppressive hybridization / イタイイタイ病 / エストロゲン受容体 / 内分泌攪乱物質 / endocline disruptor / itai-itai disease / estrogen receptor / polymorphism / メッセンジャーRNA前躯体 / スプライシング促進配列 / dsx遺伝子 / ミニ遺伝子 / 抗SMN抗体 / メッセンジャーRNA前駆体 / SMN蛋白 / 可変スプライシング / pre-mRNA / splicing / splicing enhancer sequences / the dsx gene / mini-gene / anti-SMN antibody / in vitroスプライシング / in vitro splicing assay / peptide nucleic acid / エクソン特異的スプライシング促進化合物 / バルプロ酸 / ヒストン脱アセチル化酵素阻害剤 / 転写効率 / スプライシング効率 / エクソン7 / 遺伝子変異 / Tudorドメイン / thetic exon-specific splicing activator / valproic acid Less
  • Research Projects

    (13 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (7 People)
  •  Role of Rab family small G proteins in determining the prognosis of neuroblastoma patientsPrincipal Investigator

    • Principal Investigator
      LEE Myeongjin
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Research on splicing mechanism using a metal which disrupts splicing reactionPrincipal Investigator

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation Technology

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and KoreanPrincipal Investigator

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Kobe University
  •  Research on the effect of carcinogenic chemical compounds on alternative splicingPrincipal Investigator

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  Development of a new treatment with splicing modulators for spinal muscular atrophy

    • Principal Investigator
      NSIHIO Hisahide
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Screening system for chemicals attacking pre-mRNA splicing machinery in cells

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University Graduate School of medicine
  •  Detection of endocrine disruptor effect using Microphysiometer SystemPrincipal Investigator

    • Principal Investigator
      LEE Myeong jin
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  アルツハイマー病アミロイド・ベーター蛋白の毒性発現の抑制機構(メタロチオネイン及びその類似蛋白とアルミニウムの影響)

    • Principal Investigator
      SUMINO Kimiaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  Molecular biological studies on environmental chemical pollutants interfering with endocrine systems

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Public health/Health science
    • Research Institution
      Kobe University
  •  東アジア諸国の成人病関連遺伝子変異に関する研究Principal Investigator

    • Principal Investigator
      李 明鎭
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Public health/Health science
    • Research Institution
      Kobe University
  •  リンパ球特異的に発現するL-ジストロフィンの発現制御機構に関する研究

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Molecular Biological Analysis of Cells and Tissues from Animals Exposed to Chemicals and Ultraviolet Rays

    • Principal Investigator
      SUMINO Kimiaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University

All 2012 2011 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells2012

    • Author(s)
      Nishimura N, Hartomo TB, Pham TVH, Lee MJ, Yamamoto T, Morikawa S, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H
    • Journal Title

      Environ. Health Prev. Med

      Volume: 17 Pages: 246-251

    • NAID

      10030617244

    • Data Source
      KAKENHI-PROJECT-21591361
  • [Journal Article] Rab15 alternative splicing is altered in spheres of neuroblastoma cells2012

    • Author(s)
      Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Ishida T, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H and Nishimura N
    • Journal Title

      Oncol. Rep

      Volume: 27 Pages: 2045-2049

    • Data Source
      KAKENHI-PROJECT-21591361
  • [Journal Article] Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells2011

    • Author(s)
      Nishimura N, Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Nishio H and Matsuo M
    • Journal Title

      Oncol. Rep

      Volume: 26 Pages: 145-151

    • Data Source
      KAKENHI-PROJECT-21591361
  • [Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure2008

    • Author(s)
      Gunadi, Sasongko, TH, Yusoff, S, Lee, MJ, Nishioka, E, Matsuo, M, Nishio, H
    • Journal Title

      Ann Hum Genet 72(2)

      Pages: 288-291

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] SMN2 and NAP gene dosages in Vietnamese patients with spinal muscular atrophy2008

    • Author(s)
      Van, Khanh, TV, Teguh, Haryo, Sasongko, Dang, Diem Hong , Nguyen, Thi, Hoan, Vu, Chi, Dung, Myeongn Jin Lee , Gunadi, Indra, Sari, Kusuma, Harahap, Yasuhiro, Takeshima, Masafumi, Matsuo, Hisahide, Nishio
    • Journal Title

      Pediatr Int (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure.2008

    • Author(s)
      Gunadi, Sasongko TH, Yusoff S, Lee MJ, Nishioka E, matsuo M, Nishio H.
    • Journal Title

      Ann Hum Genet. 72

      Pages: 288-291

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] SMN2 and NAIP gene dosages in Vietnamese patients with spinal muscular atrophy.2008

    • Author(s)
      Van Khanh TV, Teguh Haryo Sasongko, Dang Diem Hong, Nguyen Thi Hoan, Vu Chi Dung, Myeong Jin Lee, Gunadi, Indra Sari Kusumma Harahap, Yasuhiro Takeshima, Masafumi Matsuo and Hisahide Nishio.
    • Journal Title

      Pediatrics International (in press)

    • NAID

      10025343726

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

    • Author(s)
      Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
    • Journal Title

      J Neurol. 80

      Pages: 624-630

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007

    • Author(s)
      Kotani, T, Sutomo, R, Sasongko, TH, Sadewa, AH, Gunadi, Minato, T,Fujii, E, Endo, S, Lee, MJ, Ayaki, H, Harada, Y, Matsuo, M, Nishio, H
    • Journal Title

      J Neurol 254(5)

      Pages: 624-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

    • Author(s)
      Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
    • Journal Title

      J Neurol. 254

      Pages: 624-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006

    • Author(s)
      Lee, MJ, Ayaki, H, Goji, J, Kitamura, K, Nishio, H
    • Journal Title

      Arch Toxicol 80(10)

      Pages: 638-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006

    • Author(s)
      Myeong Jin, Lee
    • Journal Title

      Archives of Toxicology (Epub ahead of print)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590475
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006

    • Author(s)
      Lee MJ, Ayaki H, Goji J, Kitamura K, Nishio
    • Journal Title

      Arch Toxicol. 80

      Pages: 638-643

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006

    • Author(s)
      Myeong Jin Lee
    • Journal Title

      Arch Toxicol (Epub ahead of print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590475
  • [Journal Article] Cadmium exposure induces expression of the HOXB8 gene in COS-7 cells

    • Author(s)
      Kanako, Nakagawa, Myeong, Jin Lee, Naokom Sasaki, Chiyo, Hayashi, Hisahide, Nishio
    • Journal Title

      Toxicology in Vitro (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590556
  • [Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins.2006

    • Author(s)
      Nishio H, Lee MJ, Kotani T, Sutomo R, interaction with target proteins. Nishio H, Lee MJ, Kotani T, Sutomo R, Sadewa AH, Sasongko TH, Gunadi, Matsuo M.
    • Organizer
      The American Society of Human Genetics 56th Annual Meeting,
    • Place of Presentation
      New Orleans
    • Year and Date
      2006-11-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins2006

    • Author(s)
      Nishio, H, Lee, MJ, Kotani, T, Sutomo, R, Sadewa, AH, Sasongko, TH, Gunadi
    • Organizer
      The American Society of Human Genetics 56th Annual Meeting
    • Place of Presentation
      New Orleans, Louisiana
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • 1.  NISHIO Hisahide (80189258)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 15 results
  • 2.  AYAKI Hitoshi (80222701)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 3.  SUMINO Kimiaki (90030832)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  MATSUO Masafumi (10157266)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TAKESIMA Ysuhiro (40281141)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  NISHIMURA Noriyuki (00322719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  西本 啓介 (00362773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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