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Ayaki Hitoshi  綾木 仁

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… Alternative Names

AYAKI Hitoshi  綾木 仁

綾木 仁  アヤキ ヒトシ

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Researcher Number 80222701
Affiliation (Current) 2022: 関西福祉科学大学, 健康福祉学部, 教授
Affiliation (based on the past Project Information) *help 2007: 広島文教女子大学, 人間科学部, 教授
2006: Kobe University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授
2005 – 2006: Kobe University, Graduate School of Medicine, Associate Professor, 医学系研究科, 助教授
2005: 神戸大学, 医学研究科, 助教授
2002 – 2004: Kobe University Graduate School of medicine Associate Professor, 大学院・医学系研究科, 助教授 … More
2002: 神戸大学, 医学系研究科, 助教授
2001: 神戸大学, 大学院・医学系研究科, 講師
1994: 京都大学, 放射線生物研究センター, 助手
1991: 京都大学, 放射線生物研究センター, 助手 Less
Review Section/Research Field
Principal Investigator
環境影響評価(含放射線生物学)
Except Principal Investigator
Pediatrics / Hygiene / Applied genomics / Hygiene / Public health/Health science
Keywords
Principal Investigator
コケイン症候群 / A群原因遺伝子 / クローニング / cDNA発現ライブラリー
Except Principal Investigator
脊髄性筋萎縮症 / spinal muscular atrophy / スプライシング / カドミウム / SMN1遺伝子 / SMN2遺伝子 … More / hnRNP C1 / C2 / in vitroスプライシング / ペプチド核酸 / the SMN1 gene / the SMN2 gene / G71R / Cd / ZNF265 / HOXB8 / BRCA1 / BRCA2 / メチル転移酵素 / アルキル化剤 / ヒト腫瘍細胞 / Mer^ー形質 / 遺伝子発現制御 / 選択的化学療法 / 遺伝子クローニング / ブリッジヌクレオチド法 / oligo(dG)latex bead / cDNAクローニング法 / oligo(dG) latex bead / cDNA / oligo (dG) latex bead / メッセンジャーRNA前躯体 / スプライシング促進配列 / dsx遺伝子 / ミニ遺伝子 / 抗SMN抗体 / メッセンジャーRNA前駆体 / SMN蛋白 / 可変スプライシング / pre-mRNA / splicing / splicing enhancer sequences / the dsx gene / mini-gene / anti-SMN antibody / cadmium / in vitro splicing assay / peptide nucleic acid / 発がん性化学物質 / 選択的スプライシング / ホメオボックス遺伝子 / スプライシング関連因子 / 重金属 / Carcinogenic compound / Alternative splicing / Cadmium / Homeobox gene / Spliceosomal protein / 日本人 / 韓国人 / 乳がん / UGT1A1遺伝子 / -3279 T>G / UGT遺伝子 / Japanese / Korean / breast cancer / UGT1A1 gene / -3279T>G / スプライシング関連蛋白 / SMN遺伝子 / HOX遺伝子 / splicing related protein / SMN gene / HOX gene / エクソン特異的スプライシング促進化合物 / バルプロ酸 / ヒストン脱アセチル化酵素阻害剤 / 転写効率 / スプライシング効率 / エクソン7 / 遺伝子変異 / Tudorドメイン / thetic exon-specific splicing activator / valproic acid Less
  • Research Projects

    (9 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (11 People)
  •  Research on splicing mechanism using a metal which disrupts splicing reaction

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation Technology

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  ブリッジヌクレオチド法による遺伝子cDNAの迅速(1日以内)クローニング法の開発

    • Principal Investigator
      榎本 平
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied genomics
    • Research Institution
      Kobe University
  •  The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and Korean

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Kobe University
  •  Research on the effect of carcinogenic chemical compounds on alternative splicing

    • Principal Investigator
      LEE Myeong Jin
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University
  •  Development of a new treatment with splicing modulators for spinal muscular atrophy

    • Principal Investigator
      NSIHIO Hisahide
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kobe University
  •  Screening system for chemicals attacking pre-mRNA splicing machinery in cells

    • Principal Investigator
      NISHIO Hisahide
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kobe University Graduate School of medicine
  •  コケイン症候群A群原因遺伝子のクローニングPrincipal Investigator

    • Principal Investigator
      綾木 仁
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Kyoto University
  •  O^6ーアルキルグアニンーアルキル転移酵素の制がんと発がんにおける役割

    • Principal Investigator
      池永 満生
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University

All 2007 2006

All Journal Article

  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

    • Author(s)
      Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
    • Journal Title

      J Neurol. 254

      Pages: 624-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007

    • Author(s)
      Kotani, T, Sutomo, R, Sasongko, TH, Sadewa, AH, Gunadi, Minato, T,Fujii, E, Endo, S, Lee, MJ, Ayaki, H, Harada, Y, Matsuo, M, Nishio, H
    • Journal Title

      J Neurol 254(5)

      Pages: 624-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

    • Author(s)
      Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
    • Journal Title

      J Neurol. 80

      Pages: 624-630

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006

    • Author(s)
      Lee, MJ, Ayaki, H, Goji, J, Kitamura, K, Nishio, H
    • Journal Title

      Arch Toxicol 80(10)

      Pages: 638-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591151
  • [Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006

    • Author(s)
      Lee MJ, Ayaki H, Goji J, Kitamura K, Nishio
    • Journal Title

      Arch Toxicol. 80

      Pages: 638-643

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591151
  • 1.  LIEE Jin (20273766)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 2.  NISHIO Hisahide (80189258)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 3.  MATSUO Masafumi (10157266)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TAKESIMA Ysuhiro (40281141)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  池永 満生 (70025378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  許 南浩 (70173573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  峯浦 一喜 (70134103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  作見 邦彦 (50211933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  中別府 雄作 (30180350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  榎本 平 (00127622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  西本 啓介 (00362773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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