AYAKI Hitoshi 綾木仁

… Alternative Names

綾木仁アヤキヒトシ

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Researcher Number	80222701
Affiliation (based on the past Project Information) *help	2007: 広島文教女子大学, 人間科学部, 教授 2006: Kobe University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 2005 – 2006: Kobe University, Graduate School of Medicine, Associate Professor, 医学系研究科, 助教授 2005: 神戸大学, 医学研究科, 助教授 2002 – 2004: Kobe University Graduate School of medicine Associate Professor, 大学院・医学系研究科, 助教授 … More 2002: 神戸大学, 医学系研究科, 助教授 2001: 神戸大学, 大学院・医学系研究科, 講師 1994: 京都大学, 放射線生物研究センター, 助手 1991: 京都大学, 放射線生物研究センター, 助手 Less
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) Except Principal Investigator Hygiene / Pediatrics / Public health/Health science / Hygiene / Applied genomics
Keywords	Principal Investigator cDNA発現ライブラリー / クローニング / A群原因遺伝子 / コケイン症候群 Except Principal Investigator spinal muscular atrophy / 脊髄性筋萎縮症 / BRCA2 / BRCA1 / HOXB8 / ZNF265 … More / Cd / G71R / the SMN2 gene / the SMN1 gene / ペプチド核酸 / in vitroスプライシング / C2 / hnRNP C1 / SMN2遺伝子 / SMN1遺伝子 / カドミウム / スプライシング / valproic acid / thetic exon-specific splicing activator / Tudorドメイン / 遺伝子変異 / エクソン7 / スプライシング効率 / 転写効率 / ヒストン脱アセチル化酵素阻害剤 / バルプロ酸 / エクソン特異的スプライシング促進化合物 / HOX gene / SMN gene / splicing related protein / HOX遺伝子 / SMN遺伝子 / スプライシング関連蛋白 / -3279T>G / UGT1A1 gene / breast cancer / Korean / Japanese / UGT遺伝子 / -3279 T>G / UGT1A1遺伝子 / 乳がん / 韓国人 / 日本人 / Spliceosomal protein / Homeobox gene / Cadmium / Alternative splicing / Carcinogenic compound / 重金属 / スプライシング関連因子 / ホメオボックス遺伝子 / 選択的スプライシング / 発がん性化学物質 / peptide nucleic acid / in vitro splicing assay / cadmium / anti-SMN antibody / mini-gene / the dsx gene / splicing enhancer sequences / splicing / pre-mRNA / 可変スプライシング / SMN蛋白 / メッセンジャーRNA前駆体 / 抗SMN抗体 / ミニ遺伝子 / dsx遺伝子 / スプライシング促進配列 / メッセンジャーRNA前躯体 / oligo (dG) latex bead / cDNA / oligo(dG) latex bead / cDNAクローニング法 / oligo(dG)latex bead / ブリッジヌクレオチド法 / 遺伝子クローニング / 選択的化学療法 / 遺伝子発現制御 / Mer^ー形質 / ヒト腫瘍細胞 / アルキル化剤 / メチル転移酵素 Less

Research on splicing mechanism using a metal which disrupts splicing reaction
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation Technology
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
ブリッジヌクレオチド法による遺伝子cDNAの迅速(1日以内)クローニング法の開発
- Principal Investigator
  
  榎本平
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Kobe University
The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and Korean
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
Research on the effect of carcinogenic chemical compounds on alternative splicing
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Development of a new treatment with splicing modulators for spinal muscular atrophy
- Principal Investigator
  
  NSIHIO Hisahide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Screening system for chemicals attacking pre-mRNA splicing machinery in cells
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University Graduate School of medicine
コケイン症候群A群原因遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  綾木仁
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
O^6ーアルキルグアニンーアルキル転移酵素の制がんと発がんにおける役割
- Principal Investigator
  
  池永満生
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University

All 2007 2006

All Journal Article

[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 254
  
  Pages: 624-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007
- Author(s)
  Kotani, T, Sutomo, R, Sasongko, TH, Sadewa, AH, Gunadi, Minato, T,Fujii, E, Endo, S, Lee, MJ, Ayaki, H, Harada, Y, Matsuo, M, Nishio, H
- Journal Title
  
  J Neurol 254(5)
  
  Pages: 624-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 80
  
  Pages: 624-630
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006
- Author(s)
  Lee, MJ, Ayaki, H, Goji, J, Kitamura, K, Nishio, H
- Journal Title
  
  Arch Toxicol 80(10)
  
  Pages: 638-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006
- Author(s)
  Lee MJ, Ayaki H, Goji J, Kitamura K, Nishio
- Journal Title
  
  Arch Toxicol. 80
  
  Pages: 638-643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151

1. LIEE Jin (20273766)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
2. NISHIO Hisahide (80189258)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
3. MATSUO Masafumi (10157266)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKESIMA Ysuhiro (40281141)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 池永満生 (70025378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 許南浩 (70173573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 峯浦一喜 (70134103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 作見邦彦 (50211933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中別府雄作 (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 榎本平 (00127622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 西本啓介 (00362773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AYAKI Hitoshi 綾木 仁

綾木 仁 アヤキ ヒトシ

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コケイン症候群A群原因遺伝子のクローニングPrincipal Investigator

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[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

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[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007

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[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007

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[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006

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[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006

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AYAKI Hitoshi 綾木仁

綾木仁アヤキヒトシ