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AZAKAMI DAIGO  呰上 大吾

… Alternative Names

呰上 大吾  アザカミ ダイゴ

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Researcher Number 80453934
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4512-8599
Affiliation (Current) 2025: 東京農工大学, (連合)農学研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 東京農工大学, (連合)農学研究科(研究院), 准教授
2016 – 2017: 日本獣医生命科学大学, 獣医学部, 准教授
2015: 日本獣医生命科学大学, 獣医学部, 講師
Review Section/Research Field
Except Principal Investigator
Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords
Except Principal Investigator
犬 / オルガノイド / 猫 / 耐性 / チロシンキナーゼ阻害剤 / 肥満細胞腫 / 薬物動態 / 薬物動態解析 / 抗がん剤 / 乳がん … More / がん免疫療法 / オーガンオンチップ / 膀胱がん / 腫瘍性疾患 / 炎症性疾患 / 免疫寛容 / 腫瘍 / 腸炎 / IDO1 / KIT変異 / チロシンキナーゼ / トセラニブ / 個別化治療 / 耐性化 / 乳癌 / 横紋筋肉腫 / 炎症性乳癌 / がん幹細胞 / 自己複製能 / 癌幹細胞 / がん / イマチニブ / 獣医腫瘍学 / 獣医臨床病理学 / 獣医学 / KIT / ARシグナル伝達 / ホルモン療法抵抗性 / イヌ / SGTA / REIC/Dkk-3 / 前立腺がん Less
  • Research Projects

    (7 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (24 People)
  •  Elucidation of the mechanism of cancer progression and acquisition of resistance to therapy by utilizing bladder organoids derived from urine samples.

    • Principal Investigator
      臼井 達哉
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Elucidation of the regulatory mechanism of feline mammary carcinoma by integrating three-dimensional culture and pharmacokinetic analysis

    • Principal Investigator
      佐々木 一昭
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Expression and functional analysis of IDO1, an immunological tolerance system, in canine inflammatory and neoplastic disease.

    • Principal Investigator
      Ide Kaori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Analysis of diversity in tyrosine kinase inhibitor resistance in mast cell tumors toward establishment of individualized therapy

    • Principal Investigator
      Bonkobara Makoto
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Establishment of the new strategy with REIC/Dkk-3 against androgen independent prostate cancer.

    • Principal Investigator
      Ochiai Kazuhiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Studies on the mechanisms and therapeutic approach for resistance of tyrosine kinase inhibitors in mast cell tumour

    • Principal Investigator
      BONKOBARA MAKOTO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Identification and clinical application of cancer stem cells derived from canine refractory cancers

    • Principal Investigator
      Michishita Masaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Nippon Veterinary and Life Science University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Nimustine Treatment of 11 Cases of Canine Histiocytic Sarcoma.2020

    • Author(s)
      Tani H, Kurita S, Miyamoto R, Sawada H, Fujiwara-Igarashi A, Michishita M, Azakami D, Hasegawa D, Tamura K, Bonkobara M.
    • Journal Title

      J Am Anim Hosp Assoc.

      Volume: 56 Issue: 3 Pages: 146-146

    • DOI

      10.5326/jaaha-ms-6959

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-19J15532, KAKENHI-PROJECT-19H03131
  • [Journal Article] Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation2018

    • Author(s)
      Kawakami S, Ochiai K, Kato Y, Michishita M, Hirama H, Obara R, Azakami D, Watanabe M, Omi T
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 80 Issue: 1 Pages: 85-91

    • DOI

      10.1292/jvms.17-0362

    • NAID

      130006321212

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-15K07754
  • [Journal Article] R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes.2018

    • Author(s)
      Kawakami S, Ochiai K, Azakami D, Kato Y, Michishita M, Morimatsu M, Ishiguro-Oonuma T, Onozawa E, Watanabe M, Omi T.
    • Journal Title

      Vet Res Commun

      Volume: 42(1) Issue: 1 Pages: 49-56

    • DOI

      10.1007/s11259-017-9707-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07754
  • [Journal Article] MicroRNA expression profiling in canine prostate cancer2017

    • Author(s)
      Kobayashi M, Saito A, Tanaka Y, Michishita M, Kobayashi M, Irimajiri M, Kaneda T, Ochiai K, Bonkobara M, Takahashi K, Hori T, Kawakami E
    • Journal Title

      Journal of Veterianry Medical Science

      Volume: 79 Issue: 3 Pages: 719-725

    • DOI

      10.1177/1040638717698179

    • NAID

      130005549028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Journal Article] Pancreatic Colloid Carcinoma in an Elderly Cat2017

    • Author(s)
      Hagiwara K.、Michishita M.、Yoshimura H.、Ochiai K.、Azakami D.、Ishiwata T.、Takahashi K.
    • Journal Title

      Journal of Comparative Pathology

      Volume: 157 Issue: 4 Pages: 266-269

    • DOI

      10.1016/j.jcpa.2017.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Journal Article] Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines2017

    • Author(s)
      Kato Yuiko、Ochiai Kazuhiko、Kawakami Shota、Nakao Nobuhiro、Azakami Daigo、Bonkobara Makoto、Michishita Masaki、Morimatsu Masami、Watanabe Masami、Omi Toshinori
    • Journal Title

      BMC Veterinary Research

      Volume: 13 Issue: 1 Pages: 170-170

    • DOI

      10.1186/s12917-017-1094-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08053, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K07754
  • [Journal Article] Oncocytic carcinoma of the salivary gland in a dog.2017

    • Author(s)
      Nakahira R, Michishita M, Kato M, Okuno Y, Hatakeyama H, Yoshimura H, Azakami D, Ochiai K, Bonkobara M, Takahashi K.
    • Journal Title

      J Vet Diagn Invest

      Volume: 29 Issue: 1 Pages: 105-108

    • DOI

      10.1177/1040638716673126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-26292161
  • [Journal Article] Properties of the feline tumour suppressor reduced expression in immortalized cells (REIC/Dkk-3).2017

    • Author(s)
      Ochiai K, Oda H, Shono S, Kato Y, Sugihara S, Nakazawa S, Azakami D, Michishita M, Onozawa E, Bonkobara M, Sako T, Shun-Ai L, Ueki H, Watanabe M, Omi T.
    • Journal Title

      Vet Comp Oncol

      Volume: In press Issue: 4 Pages: 1181-1186

    • DOI

      10.1111/vco.12254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K07754
  • [Journal Article] Identification of tumor-initiating cells derived from two canine rhabdomyosarcoma cell lines2017

    • Author(s)
      Kishimoto TE, Yashima S, Nakahira R, Onozawa E, Azakami D, Ujike M, Ochiai K, Ishiwata T, Takahashi K, Michishita M.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 79 Issue: 7 Pages: 1155-1162

    • DOI

      10.1292/jvms.16-0412

    • NAID

      130005712508

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Journal Article] Disseminated histiocytic sarcoma with hemophagocytosis in a rabbit2017

    • Author(s)
      Ishimori M, Michishita M, Yoshimura H, Azakami D, Ochiai K, Ishiwata T, Takahashi K
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 79 Issue: 9 Pages: 1503-1506

    • DOI

      10.1292/jvms.17-0297

    • NAID

      130006073235

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Journal Article] Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity2016

    • Author(s)
      Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 3 Pages: 3283-3296

    • DOI

      10.18632/oncotarget.6488

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462478, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15K07754
  • [Journal Article] Primary T-cell high-grade lymphoma of the feline uterus2016

    • Author(s)
      Azakami D, Onozawa E, Miyabe M, Ochiai K, Michishita M, Hirano T, Momota Y, Ishioka K, Sako T.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 78 Issue: 5 Pages: 913-916

    • DOI

      10.1292/jvms.15-0575

    • NAID

      130005154279

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Journal Article] Molecular Characterization of the Cytidine Monophosphate-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Associated with the Feline AB Blood Group System.2016

    • Author(s)
      Omi T, Nakazawa S, Udagawa C, Tada N, Ochiai K, Chong YH, Kato Y, Mitsui H, Gin A, Oda H, Azakami D, Tamura K, Sako T, Inagaki T, Sakamoto A, Tsutsui T, Bonkobara M, Tsuchida S, Ikemoto S.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 10 Pages: e0165000-e0165000

    • DOI

      10.1371/journal.pone.0165000

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K18798, KAKENHI-PROJECT-16K08062
  • [Journal Article] The canine prostate cancer cell line CHP-1 shows over-expression of the co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α2016

    • Author(s)
      Azakami, D., Nakahira, R., Kato, Y., Michishita, M., Kobayashi, M., Onozawa, E., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., Ishioka, K., Sako, T., Ochiai, K., and Omi, T.
    • Journal Title

      Veterinary and Compapative Oncology

      Volume: 印刷中 Issue: 2 Pages: 557-562

    • DOI

      10.1111/vco.12199

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15H04297
  • [Journal Article] Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer.2015

    • Author(s)
      Kato, Y., Ochiai, K., Michishita, M., Azakami, D., Nakahira, R., Morimatsu, M., Ishiguro-Oonuma, T., Yoshikawa, Y., Kobayashi, M., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., and Omi, T.
    • Journal Title

      The Vwterinary Journal

      Volume: 206 Issue: 2 Pages: 145-148

    • DOI

      10.1016/j.tvjl.2015.08.002

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-13J10765, KAKENHI-PROJECT-26292161
  • [Journal Article] Identification of tumor-initiating cells in canine hepatocellular carcinoma cell line2014

    • Author(s)
      Masaki Michishita, Shiori Ezaki, Kikumi Ogihara, Yuko Naya, Daigo Azakami, Takayuki Nakagawa, Nobuo Sasaki, Toshiro Arai, Kimimasa Takahashi
    • Journal Title

      Research in Veterinary Science

      Volume: 96 Issue: 2 Pages: 315-322

    • DOI

      10.1016/j.rvsc.2014.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24780314, KAKENHI-PROJECT-26292161
  • [Presentation] 猫乳腺腫瘍オルガノイドの遺伝子解析による新規治療標的の探索2023

    • Author(s)
      山本晴、モハメドエルバダウィー、佐藤よもぎ、松井里穂、魚本涼加、小林美央、吉田敏則、渋谷淳、小林哲也、井上舞、呰上大吾、東中翠、篠原祐太、臼井達哉、佐々木一昭
    • Organizer
      第27回日本獣医がん学会
    • Data Source
      KAKENHI-PROJECT-23K21268
  • [Presentation] 猫乳腺腫瘍オルガノイド培養法を利用した抗がん剤感受性検査の開発2022

    • Author(s)
      山本晴、モハメドエルバダウィー、佐藤よもぎ、松井里穂、魚本涼加、小林美央、吉田敏則、渋谷淳、小林哲也、井上舞、呰上大吾、東中翠、篠原祐太、臼井達哉、佐々木一昭
    • Organizer
      第25回日本獣医がん学会
    • Data Source
      KAKENHI-PROJECT-23K21268
  • [Presentation] 猫乳腺腫瘍オルガノイド培養法の樹立とその有用性の検証2021

    • Author(s)
      山本晴、モハメドエルバダウィー、佐藤よもぎ、松井里穂、魚本涼加、小林美央、吉田敏則、渋谷淳、小林哲也、井上舞、呰上大吾、東中翠、篠原祐太、臼井達哉、佐々木一昭
    • Organizer
      第44回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-23K21268
  • [Presentation] 腫瘍随伴性皮膚炎が疑われた膵臓癌の猫の1例2017

    • Author(s)
      南 智彦、小宮 拓巳、元風呂 晃、高橋 一真、鳥居 佳子、浦野 貴美代、道下 正貴、吉村 久志、山本 昌美、百田 豊、呰上 大吾1
    • Organizer
      第17回日本獣医がん学会
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Presentation] がん抑制遺伝子REIC/Dkk-3ネコホモログの構造と乳腺腫瘍に対するアポトーシス誘導能の解析2017

    • Author(s)
      落合和彦、杉原思穂、小田民美、川上翔太、平間日奈子、呰上大吾、近江俊徳
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K07754
  • [Presentation] CMAH遺伝子解析による猫 AB式血液型の分子基盤2017

    • Author(s)
      近江俊徳、中澤翔太、宇田川智野、多田尚美、三井寛子、落合和彦、 加藤由比子、呰上大吾、左向敏紀、筒井敏彦、盆子原誠、土田修一
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K07754
  • [Presentation] イヌSGTAホモログのクローニングと前立腺がん細胞のアンドロゲンシグナル伝達機構に与える影響の検討2015

    • Author(s)
      落合和彦、加藤由比子、中平嶺、道下正貴、呰上大吾、高橋公正、近江俊徳
    • Organizer
      日本獣医臨床病理学会2015年大会
    • Place of Presentation
      日本獣医生命科学大学(東京)
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15K07754
  • [Presentation] 前立腺がん関連遺伝子SGTAイヌホモログの構造および機能解析2015

    • Author(s)
      加藤由比子、落合和彦、中平嶺、道下正貴、呰上大吾、高橋公正、近江俊徳
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(青森県十和田市)
    • Year and Date
      2015-09-07
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Presentation] 前立腺がん関連遺伝子SGTAイヌホモログの構造および機能解析2015

    • Author(s)
      加藤由比子。落合和彦。中平嶺、道下正貴、呰上大吾、高橋公正、近江俊徳
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(青森)
    • Year and Date
      2015-09-07
    • Data Source
      KAKENHI-PROJECT-15K07754
  • [Presentation] イヌSGTAホモログのクローニングと前立腺がん細胞のアンドロゲンシグナル伝達機構に与える影響の検討2015

    • Author(s)
      落合和彦、加藤由比子、中平嶺、道下正貴、呰上大吾、高橋公正、近江俊徳
    • Organizer
      日本獣医臨床病理学会2015年大会
    • Place of Presentation
      日本獣医生命科学大学(東京都武蔵野市)
    • Year and Date
      2015-05-31
    • Data Source
      KAKENHI-PROJECT-26292161
  • [Presentation] イヌ横紋筋肉腫株化細胞由来sphereの特性解析

    • Author(s)
      岸本拓也、八嶋翔子、中平嶺、小野沢栄里、呰上大吾、髙橋公正、道下正貴
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学高等教育推進機構
    • Year and Date
      2014-09-09 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-26292161
  • 1.  BONKOBARA MAKOTO (50343611)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  Ochiai Kazuhiko (30550488)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  Michishita Masaki (50434147)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 4.  佐々木 崇 (50723897)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAMURA KYOICHI (00722282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  NAKAGAWA TAKAYUKI (40447363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ICHIKAWA HITOSHI (30201924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIMURA HISASHI (70645241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  Ide Kaori (40550281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  石渡 俊行 (90203041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  田崎 弘之 (80231405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  臼井 達哉 (80727652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  恒富 亮一 (10420514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  水野 拓也 (90398826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  川野 竜司 (90401702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  佐々木 一昭 (10421934)
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  • 17.  中尾 洋一 (60282696)
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  • 18.  ARIIZUMI KIYOSHI
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  • 19.  YASUDA AKIKO
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  • 20.  SHIGIHARA KAE
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  • 21.  NAKAHIRA REI
    # of Collaborated Projects: 1 results
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  • 22.  NAKAO Nobuhiro
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  • 23.  植木 英雄
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  • 24.  那須 保友
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