Lazarus Michael ラザルスミハエル

… Alternative Names

LAZARUS Michael ラザルスミハエル

LAZARUS Michae ラザルスミハイル

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Researcher Number	80469650
Other IDs	https://orcid.org/0000-0003-3863-4474
Affiliation (Current)	2024: 筑波大学, 国際統合睡眠医科学研究機構, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 筑波大学, 国際統合睡眠医科学研究機構, 教授 2020: 筑波大学, International Institute for Integrative Sleep Medicine, associate professor 2013 – 2020: 筑波大学, 国際統合睡眠医科学研究機構, 准教授 2016: 筑波大学, 国際統合睡眠医科学研究機構, 若手フェロー 2012: 公益財団法人大阪バイオサイエンス研究所, 研究員 … More 2011: 公益財団法人大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員 2011: 大阪バイオサイエンス研究所, 研究員 2011: 財団法人大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員 2009 – 2010: Osaka Bioscience Institute, 分子行動生物学部門, 研究員 Less
Review Section/Research Field	Principal Investigator Complex systems / Basic Section 51020:Cognitive and brain science-related / Neurophysiology / General neuroscience / Environmental physiology(including physical medicine and nutritional physiology) / Transformative Research Areas, Section (III) / Basic / Social brain science / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology Except Principal Investigator Food science / Biological Sciences / Nerve anatomy/Neuropathology
Keywords	Principal Investigator sleep / 薬理遺伝学 / Sleep / 睡眠 / Glia / 意志動力学 / 食欲 / レム睡眠 / 記憶固定 / 低体温状態 … More / 光遺伝学 / Nucleus accumbens / Nucleus Accumbens / 受容体 / 覚醒 / アデノ随伴ウィルス / カフェイン / 側坐核 / scRNAseq / glia / Parkinson's disease / Parkinson disease / apetite / appetite / Immunity / Gliosomnia / REM sleep / Motivation / nucleus accumbens / motivation / 随伴ウィルス / 薬理学 / Adeno-associated virus / Caffeine / Adenosine / Pharmacogenetics / Optogenetics / loxPシステム / Cre / 局所的RNAi干渉法 / Cre/loxPシステム / ラット / マウス / 局所的RNA干渉 / 神経回路網 … More Except Principal Investigator ノックアウトマウス / 分子シャペロン / 小胞体 / ER-60 / 創薬科学 / 脳機能 / 神経生物学 / 睡眠 / 酵素 / タンパク質結晶構造解析 / アルツハイマー病 / 結晶構造解析 / アミロイドβペプチド / エネルギー代謝 / 慢性睡眠不足 / モデルマウス / 慢性的短眠 / 血清トリアシルグリセロール / アポリポプロテインB-100 / X線結晶構造解析 / アミロイドβ / 小胞体ストレス Less

Gliosomnia and immunity: decoding brain-immune interactions in sleepPrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  University of Tsukuba
Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists
- Principal Investigator
  
  柳沢正史
- Project Period (FY)
  2022 – 2028
- Research Category
  
  Fund for the Promotion of Joint International Research (International Leading Research )
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Understanding the mechanism of sleepiness by exploring mesolimbic glia-neuron interactionsPrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  University of Tsukuba
WillDynamics of REM sleep and appetitePrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Risk of hypothermia for memory functionPrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  University of Tsukuba
Neuronal mechanisms of sleep alterations in Parkinson's Disease: A circuit based investigationPrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  University of Tsukuba
Will-dynamics of REM sleep and appetitePrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
The role of the nucleus accumbens in regulating slow-wave sleep by motivated behaviorPrincipal Investigator
- Principal Investigator
  
  Lazarus Michael
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  University of Tsukuba
Risk of hypothermia for memory functionPrincipal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Development of a mouse model of chronic sleep loss to elucidate the mechanism of metabolic disorder
- Principal Investigator
  
  Takata Yohko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
睡眠が認知機能の柔軟性および情動の調節に与える影響の解明Principal Investigator
- Principal Investigator
  
  ラザルスミハエル
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  University of Tsukuba
Functional analysis of ER-60, an ER chaperone by gene mamipulation and crystal structure analysis
- Principal Investigator
  
  Reiko Urade
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Kyoto University
Identification of a striatopallidal pathway facilitating sleep and wakefulnessPrincipal Investigator
- Principal Investigator
  
  LAZARUS Michael
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
  Osaka Bioscience Institute
Developing focal RNA interference for the identification of neural entry points for sleep-promoting adenosinePrincipal Investigator
- Principal Investigator
  
  LAZARUS Michael
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  公益財団法人大阪バイオサイエンス研究所
   Osaka Bioscience Institute
Studies on physiological roles of ER-60 by tissue-specific gene targeting analysis
- Principal Investigator
  
  URADE Reiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Kyoto University

[Book] Principles and Practice of Sleep Medicine (Seventh Edition)2022
- Author(s)
  Lazarus Michael, Oishi Yo, Landolt Hans Peter
- Publisher
  Elsevier
- ISBN
  9780323661898
- Data Source
  KAKENHI-PROJECT-23K21394
[Book] The Adenosinergic System - A Non-Dopaminergic Target in Parkinson’s Disease2015
- Author(s)
  Michael Lazarus and Yoshihiro Urade
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in Striatal Cholinergic Interneurons2024
- Author(s)
  Arai Masami、... 、Kambe Yuki、... 、Goshima Yoshio
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 44 Issue: 11 Pages: 1504-1523
- DOI
  10.1523/jneurosci.1504-23.2024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06151, KAKENHI-PROJECT-21K06440, KAKENHI-PROJECT-17KK0190, KAKENHI-PLANNED-20H05955, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03410, KAKENHI-PROJECT-23K21394, KAKENHI-PROJECT-23K23997
[Journal Article] Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice2023
- Author(s)
  Guo Han、Jiang Jian-Bo、Xu Wei、Zhang Mu-Tian、Chen Hui、Shi Huan-Ying、Wang Lu、He Miao、Lazarus Michael、Li Shan-Qun、Huang Zhi-Li、Qu Wei-Min
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2346-2346
- DOI
  10.1038/s41467-023-37797-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Journal Article] Prostaglandin E2 Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors2023
- Author(s)
  Mukai Yasutaka、Okubo Tatsuo S.、Lazarus Michael、Ono Daisuke、Tanaka Kenji F.、Yamanaka Akihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 43 Issue: 47 Pages: 7982-7999
- DOI
  10.1523/jneurosci.0353-23.2023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-23K21394
[Journal Article] Ventral pallidal glutamatergic neurons regulate wakefulness and emotion through separated projections2023
- Author(s)
  Luo Yan-Jia、Ge Jing、Chen Ze-Ka、Liu Zi-Long、Lazarus Michael、Qu Wei-Min、Huang Zhi-Li、Li Ya-Dong
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 8 Pages: 107385-107385
- DOI
  10.1016/j.isci.2023.107385
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Journal Article] Positive allosteric adenosine A2A receptor modulation suppresses insomnia associated with mania- and schizophrenia-like behaviors in mice2023
- Author(s)
  Lin Yang、Roy Koustav、Ioka Shuji、Otani Rintaro、Amezawa Mao、Ishikawa Yukiko、Cherasse Yoan、Kaushik Mahesh K.、Klewe-Nebenius Daniela、Zhou Li、Yanagisawa Masashi、Oishi Yo、Saitoh Tsuyoshi、Lazarus Michael
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 14 Pages: 1138666-1138666
- DOI
  10.3389/fphar.2023.1138666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14685, KAKENHI-PROJECT-22H04918, KAKENHI-PROJECT-23K21394
[Journal Article] Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice2023
- Author(s)
  Nishioka Tadaaki、Attachaipanich Suthinee、Hamaguchi Kosuke、Lazarus Michael、de Kerchove d’Exaerde Alban、Macpherson Tom、Hikida Takatoshi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2284-2284
- DOI
  10.1038/s41467-023-38025-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-21K15210, KAKENHI-PROJECT-23K24205, KAKENHI-PUBLICLY-22H05495, KAKENHI-PROJECT-23K21394, KAKENHI-PROJECT-21H02804
[Journal Article] Allosteric Modulation of Adenosine A2A Receptors as a New Therapeutic Avenue2022
- Author(s)
  Korkutata Mustafa、Agrawal Lokesh、Lazarus Michael
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 4 Pages: 2101-2101
- DOI
  10.3390/ijms23042101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Journal Article] Mesencephalic dopamine neurons are essential for modafinil‐induced arousal2021
- Author(s)
  Yang Yan Fei、Dong Hui、Shen Yan、Li Lei、Lazarus Michael、Qu Wei‐Min、Huang Zhi‐Li
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 178 Issue: 24 Pages: 4808-4825
- DOI
  10.1111/bph.15660
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Journal Article] Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors2021
- Author(s)
  Tsai Chia-Jung、Nagata Takeshi、Liu Chih-Yao、Suganuma Takaya、Kanda Takeshi、Miyazaki Takehiro、Liu Kai、Saitoh Tsuyoshi、Nagase Hiroshi、Lazarus Michael、Vogt Kaspar E.、Yanagisawa Masashi、Hayashi Yu
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 7 Pages: 109558-109558
- DOI
  10.1016/j.celrep.2021.109558
- NAID
  120007141681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21456, KAKENHI-PROJECT-21K15617, KAKENHI-PROJECT-17H06095, KAKENHI-PUBLICLY-21H00199, KAKENHI-PUBLICLY-21H00414, KAKENHI-PROJECT-20H03353, KAKENHI-PROJECT-20K06922, KAKENHI-PROJECT-22KF0048, KAKENHI-PROJECT-23K21394
[Journal Article] Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway2020
- Author(s)
  Ya-Dong Li, Yan-Jia Luo, Wei Xu, Jing Ge, Yoan Cherasse, Yi-Qun Wang, Michael Lazarus, Wei-Min Qu & Zhi-Li Huang
- Journal Title
  
  Molecular Psychiatry
  
  Volume: -
- DOI
  10.3389/fnins.2021.645877
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Journal Article] Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction2020
- Author(s)
  Honda Takato, Takata Yohko, Cherasse Yoan, Mizuno Seiya, Sugiyama Fumihiro, Takahashi Satoru, Funato Hiromasa, Yanagisawa Masashi, Lazarus Michael, Oishi Yo
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101240-101240
- DOI
  10.1016/j.isci.2020.101240
- NAID
  120007163338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06095, KAKENHI-PUBLICLY-19H05004, KAKENHI-PROJECT-20H00567, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534
[Journal Article] Sleep architecture of adenosine A2A receptor-deficient mice2020
- Author(s)
  Tsai Chia-Jung, Liu Chih-Yao, Lazarus Michael, Hayashi Yu
- Journal Title
  
  Sleep and Biological Rhythms
  
  Volume: - Issue: 3 Pages: 275-279
- DOI
  10.1007/s41105-020-00260-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04966, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-20K21456, KAKENHI-PROJECT-20H03353
[Journal Article] Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway2020
- Author(s)
  Ya-Dong Li, Yan-Jia Luo, Wei Xu, Jing Ge, Yoan Cherasse, Yi-Qun Wang, Michael Lazarus, Wei-Min Qu & Zhi-Li Huang
- Journal Title
  
  Molecular Psychiatry
  
  Volume: - Issue: 7 Pages: 2912-2928
- DOI
  10.1038/s41380-020-00906-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05004
[Journal Article] Adenosinergic control of sleep/wake behavior2019
- Author(s)
  Zhou Xuzhao, Lazarus Michael
- Journal Title
  
  Handbook of Behavioral Neuroscience
  
  Volume: 30 Pages: 1-12
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Journal Article] Gating and the Need for Sleep: Dissociable Effects of Adenosine A1 and A2A Receptors2019
- Author(s)
  Lazarus Michael、Oishi Yo、Bjorness Theresa E.、Greene Robert W.
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 740-740
- DOI
  10.3389/fnins.2019.00740
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-18H04966, KAKENHI-PUBLICLY-19H05004, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534
[Journal Article] Acute Social Defeat Stress Increases Sleep in Mice2019
- Author(s)
  Fujii Shinya、Kaushik Mahesh K.、Zhou Xuzhao、Korkutata Mustafa、Lazarus Michael
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 322-322
- DOI
  10.3389/fnins.2019.00322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-18H04966, KAKENHI-PUBLICLY-19H05004, KAKENHI-PROJECT-17H02215, KAKENHI-ORGANIZER-15H05935
[Journal Article] Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice2019
- Author(s)
  Zhou X, Oishi Y, Cherasse Y, Korkutata M, Fujii S, Lee CY, Lazarus M
- Journal Title
  
  Neurochemistry International
  
  Volume: 124 Pages: 256-263
- DOI
  10.1016/j.neuint.2019.01.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
[Journal Article] Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function2018
- Author(s)
  Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M
- Journal Title
  
  Neuropharmacology
  
  Volume: 144 Pages: 122-132
- DOI
  10.1016/j.neuropharm.2018.10.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-18H04966, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
[Journal Article] Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice2018
- Author(s)
  Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 0598-18 Issue: 47 Pages: 10080-10092
- DOI
  10.1523/jneurosci.0598-18.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PROJECT-18H02534, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
[Journal Article] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice2017
- Author(s)
  Oishi Yo、Xu Qi、Wang Lu、Zhang Bin-Jia、Takahashi Koji、Takata Yohko、Luo Yan-Jia、Cherasse Yoan、Schiffmann Serge N.、de Kerchove d’Exaerde Alban、Urade Yoshihiro、Qu Wei-Min、Huang Zhi-Li、Lazarus Michael
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-017-00781-4
- NAID
  120007134733
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18698, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359, KAKENHI-PROJECT-16H01881, KAKENHI-PUBLICLY-16H01629, KAKENHI-ORGANIZER-15H05935
[Journal Article] The control of sleep and wakefulness by mesolimbic dopamine systems2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  Neuroscience Research
  
  Volume: 118 Pages: 66-73
- DOI
  10.1016/j.neures.2017.04.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359, KAKENHI-PUBLICLY-16H01629
[Journal Article] 報酬系と睡眠・覚醒2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  医学のあゆみ
  
  Volume: 263 Pages: 761-764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02215
[Journal Article] 報酬系と睡眠・覚醒2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  医学のあゆみ
  
  Volume: 263 Pages: 761-764
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H06047
[Journal Article] Adenosine and Sleep2017
- Author(s)
  Lazarus Michael、Chen Jiang-Fan、Huang Zhi-Li、Urade Yoshihiro、Fredholm Bertil B.
- Journal Title
  
  Handbook of Experimental Pharmacology
  
  Volume: - Pages: 1-23
- DOI
  10.1007/164_2017_36
- ISBN
  9783030112707, 9783030112721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-16H01881, KAKENHI-PUBLICLY-16H01629
[Journal Article] Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice2017
- Author(s)
  Oishi Y, Suzuki Y, Takahashi K, Yonezawa T, Kanda T, Takata Y, Cherasse Y, Lazarus M
- Journal Title
  
  Brain Structure & Function
  
  Volume: - Issue: 6 Pages: 1-9
- DOI
  10.1007/s00429-017-1365-7
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-16K18358, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359
[Journal Article] 報酬系と睡眠・覚醒2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  医学のあゆみ
  
  Volume: 263 Pages: 761-764
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01629
[Journal Article] Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice.2016
- Author(s)
  Zhang BJ, Shao SR, Aritake K, Takeuchi A, Urade Y, Huang ZL, Lazarus M, Qu WM.
- Journal Title
  
  Neuroscience
  
  Volume: 340 Pages: 258-267
- DOI
  10.1016/j.neuroscience.2016.09.053
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293051, KAKENHI-PROJECT-16H01881, KAKENHI-PUBLICLY-16H01629
[Journal Article] Chemogenetic inhibition of the medial prefrontal cortex reverses the effects of REM sleep loss on sucrose consumption2016
- Author(s)
  McEown K, Takata Y, Cherasse Y, Nagata N, Aritake K, Lazarus M
- Journal Title
  
  eLife
  
  Volume: 5
- DOI
  10.7554/elife.20269
- NAID
  120007135235
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629, KAKENHI-PROJECT-14F04762, KAKENHI-PROJECT-26293051
[Journal Article] EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling2015
- Author(s)
  Lu A, Zuo C, He Y, Chen G, Piao L, Zhang J, Xiao B, Shen Y, Tang J, Kong D, Alberti S, Chen D, Zuo S, Zhang Q, Yan S, Yuan F, Zhou B, Duan SZ, Yu Y, Lazarus M, Su Y, Breyer R, Funk C, Yu Y
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 125 Issue: 3 Pages: 1228-1242
- DOI
  10.1172/jci77656
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep2015
- Author(s)
  Oishi Y, Yoshida K, Scammell TE, Urade Y, Lazarus M, Saper CB
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 47 Pages: 172-177
- DOI
  10.1016/j.bbi.2014.11.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Neuroanatomy and transgenic technologies2015
- Author(s)
  Jackson AC, Liu C, Fukuda M, Lazarus M, Gautron L
- Journal Title
  
  Frontiers in Neuroanatomy
  
  Volume: 8 Pages: 1-2
- DOI
  10.3389/fnana.2014.00157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Prostaglandin D2 is crucial for seizure suppression and postictal sleep2014
- Author(s)
  Kaushik MK, Aritake K, Kamauchi S, Hayaishi O, Huang ZL, Lazarus M, Urade Y
- Journal Title
  
  Experimental Neurology
  
  Volume: 253 Pages: 82-90
- DOI
  10.1016/j.expneurol.2013.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-25515007, KAKENHI-PROJECT-25670047
[Journal Article] Cyclical Appearance of African Trypanosomes in the Cerebrospinal Fluid: New Insights in How Trypanosomes Enter the CNS2014
- Author(s)
  Mogk S, Meiwes A, Shtopel S, Schraermeyer U, Lazarus M, Kubata B, Wolburg H, Duszenko M
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 3 Pages: e91372-e91372
- DOI
  10.1371/journal.pone.0091372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice.2014
- Author(s)
  Kaneko K, Mizushige T, Miyazaki Y, Lazarus M, Urade Y, Yoshikawa M, Kanamoto R, Ohinata K.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol.
  
  Volume: 306(4) Issue: 4 Pages: 265-272
- DOI
  10.1152/ajpregu.00405.2013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23380076, KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-24780127
[Journal Article] Acute inhibition of a cortical motor area impairs vocal control in singing zebra finches2014
- Author(s)
  Yazaki-Sugiyama Y, Yanagihara S, Fuller PM, Lazarus M
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 41 Issue: 1 Pages: 97-108
- DOI
  10.1111/ejn.12757
- NAID
  120007136463
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-24500403
[Journal Article] Concurrent and robust regulation of feeding behavions and metabolism by orexin neurons.2014
- Author(s)
  Inutsuka A, Inui A, Tabuchi S, Tsunematsu T, Lazarus M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 85 Pages: 451-460
- DOI
  10.1016/j.neuropharm.2014.06.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J04733, KAKENHI-PLANNED-23115103, KAKENHI-PROJECT-24300129, KAKENHI-PUBLICLY-26118507, KAKENHI-PROJECT-26293046, KAKENHI-PROJECT-26640041, KAKENHI-PROJECT-26860157
[Journal Article] A mouse model mimicking human first night effect for the evaluation of hypnotics2014
- Author(s)
  Xu Q, Xu XH, Qu WM, Lazarus M, Urade Y, Huang ZL
- Journal Title
  
  Pharmacology Biochemistry & Behavior
  
  Volume: 116 Pages: 129-136
- DOI
  10.1016/j.pbb.2013.11.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Glutamatergic Signaling from the Parabrachial Nucleus Plays a Critical Role in Hypercapnic Arousal2013
- Author(s)
  Kaur S, Pedersen NP, Yokota S, Hur EE, Fuller PM, Lazarus M, Chamberlin NL, Saper CB.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 33 Issue: 18 Pages: 7627-7640
- DOI
  10.1523/jneurosci.0173-13.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-24500380
[Journal Article] Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation2013
- Author(s)
  Zhang J, Xu Q, Yuan X, Cherasse Y, Schiffmann SN, De Kerchove D'Exaerde A, Qu W, Urade Y, Lazarus M, Huang ZL, Li R
- Journal Title
  
  Frontiers in neuroanatomy
  
  Volume: 7 Pages: 1-15
- DOI
  10.3389/fnana.2013.00043
- NAID
  120007130584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-25871082
[Journal Article] COX-2-Derived PGE2 Promotes Injury-Induced Vascular Neointimal HyperplasiaThrough the EP3 Receptor2013
- Author(s)
  Zhang J, Zou F, Tang J, Zhang Q, Gong y Wang Q, Slien Y Xiong L, Breyer RM, Lazarus M, Funk CD, Yu Y
- Journal Title
  
  Circulation Research
  
  Volume: (In press) Issue: 2 Pages: 104-114
- DOI
  10.1161/circresaha.113.301033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Role of the basal ganglia in the control of sleep and wakefulness2013
- Author(s)
  Lazarus, M.; Chen, J. F.; Urade, Y.; Huang, Z. L.
- Journal Title
  
  Curr Opin Neurobiol
  
  Volume: 23 Issue: 5 Pages: 780-785
- DOI
  10.1016/j.conb.2013.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300133, KAKENHI-PROJECT-24300129
[Journal Article] Characterization of ovolin, an orally active tryptic peptide released from ovalbumin with anxiolytic-like activity.2012
- Author(s)
  Oda A, Kaneko K, Mizushige T, Lazarus M, Urade Y, Ohinata K.
- Journal Title
  
  J Neurochem.
  
  Volume: 122 Issue: 2 Pages: 356-362
- DOI
  10.1111/j.1471-4159.2012.07777.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03784, KAKENHI-PROJECT-21300133, KAKENHI-PROJECT-23380076
[Journal Article] Late Stage Infection in Sleeping Sickness2012
- Author(s)
  Wolburg H, Mogk S, Acker S, Frey C, Meinert M, Schonfeld C, Lazarus M, Urade Y, Kubata BK, Duszenko M
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 3 Pages: e34304-e34304
- DOI
  10.1371/journal.pone.0034304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133, KAKENHI-PROJECT-24300129
[Journal Article] How do the basal ganglia regulate sleep-wake behavior?2012
- Author(s)
  Lazarus M, Huang ZL, Lu J,Urade Y, Chen JF.
- Journal Title
  
  Trends in Neuroscience
  
  Volume: 35 Issue: 12 Pages: 723-732
- DOI
  10.1016/j.tins.2012.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Orally administered rubiscolin-6, aδopioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocalin-type prostaglandin(PG) D synthase in mice2012
- Author(s)
  Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K.
- Journal Title
  
  Molecular Nutrition and Food Research
  
  Volume: 56巻、(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Late Stage Infection in Sleeping Sickness2012
- Author(s)
  Wolburg H, Mogk S, Acker S, Frey C, Meinert M, Schonfeld C, Lazarus M, Urade Y, Kubata BK, Duszenko M.
- Journal Title
  
  PLoS ONE
  
  Volume: 7巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens2011
- Author(s)
  Lazarus M, Shen HY, Cherasse Y, Qu WM, et.al.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin (PG) D synthase in mice2011
- Author(s)
  Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K
- Journal Title
  
  Molecular Nutrition and Food Research
  
  Volume: 56(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Genetic dissection of neural circuitry regulating behavioral state usingconditional transgenics2011
- Author(s)
  Lazarus M, Saper CB, Fuller PM
- Journal Title
  
  Sleep and Biological Rhythms
  
  Volume: 9 Pages: 1479-8425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Genetic dissection of neural circuitry regulating behavioral state using conditional transgenics2011
- Author(s)
  Lazarus M. Saper CB, Fuller PM
- Journal Title
  
  Sleep and Biological Rhythms
  
  Volume: 9巻 Pages: 1479-8425
- DOI
  10.1111/j.1479-8425.2010.00469.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Arousal effect of caffeine depends on adenosine A_<2A> receptors in the shell of the nucleus accumbens2011
- Author(s)
  Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass C, Winsky-Sommerer R, Semba K, Fredholm B, Boison D, Hayaishi O, Urade Y, Chen JF.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31巻 Issue: 27 Pages: 10067-10075
- DOI
  10.1523/jneurosci.6730-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133, KAKENHI-PROJECT-21380081, KAKENHI-PROJECT-21500313
[Journal Article] Identifying the efferent projections of leptin-responsive neurons in the dorsomedial hypothalamus using a novel conditional tracing approach2010
- Author(s)
  Gautron L, Lazarus M, Scott MM, Saper CB, Elmquist JK.
- Journal Title
  
  Journal of Comparative Neurology 518
  
  Pages: 2090-2108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Identifying the efferent projections of leptin-responsive neurons in the dorsomedial hypothalamususing a novel conditional tracing approach2010
- Author(s)
  Gautron L, Lazarus M, Scott MM, Saper CB, Elmquist JK.
- Journal Title
  
  Journal of Comparative Neurology
  
  Volume: 518巻 Issue: 11 Pages: 2090-2108
- DOI
  10.1002/cne.22323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Identifying the efferent projections of leptin-responsive neurons in the dorsomedial hypothalamus using a novel conditional tracing approach.2010
- Author(s)
  Gautron L, Lazarus M, Scott MM, Saper CB, Elmquist JK.
- Journal Title
  
  Journal of Comparative Neurology
  
  Volume: 518 Pages: 2090-2108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] COX-2 expressed in central neural cells mediates mechanicalinflammatory pain hypersensitivity2009
- Author(s)
  Vardeh D, Wang D, Costigan M, Lazarus M, Saper CB, Woolf CJ, FitzGerald GA, Samad T.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 119巻 Pages: 287-294
- DOI
  10.1172/jci37098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] COX-2 expressed in central neural cells mediates mechanical inflamematory pain hypersensitivity2009
- Author(s)
  Vardeh D, Wang D, Costigan M, Lazarus M, Saper CB, Woolf CJ, FitzGerald GA, Samad TA.
- Journal Title
  
  Journal of Clinical Investigation 119
  
  Pages: 287-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Parallel preoptic pathways for the inhibition of hyperthermia2009
- Author(s)
  Yoshida K, Li X, Cano G, Lazarus M, Saper CB.
- Journal Title
  
  Journal of Neuroscience 29
  
  Pages: 11954-11964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Parallel preoptic pathways for the inhibition of hyperthermia2009
- Author(s)
  Yoshida K, Li X, Cano G, Lazarus M. Saper CB
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 29巻 Issue: 38 Pages: 11954-11964
- DOI
  10.1523/jneurosci.2643-09.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Patent] Heterocyclic compound as sleep-inducing agent2019
- Inventor(s)
  Nagase Hiroshi, Lazarus Michael,
- Industrial Property Rights Holder
  Nagase Hiroshi, Lazarus Michael,
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H02215
[Patent] Heterocyclic compound as sleep-inducing agent2019
- Inventor(s)
  Nagase Hiroshi, Lazarus Michael,
- Industrial Property Rights Holder
  Nagase Hiroshi, Lazarus Michael,
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PUBLICLY-18H04966
[Patent] Heterocyclic compound as sleep-inducing agent2019
- Inventor(s)
  Nagase Hiroshi, Lazarus Michael
- Industrial Property Rights Holder
  筑波大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H02215
[Patent] Novel slow wave sleep-inducing agent2017
- Inventor(s)
  Lazarus Michael, Nagase Hiroshi
- Industrial Property Rights Holder
  Lazarus Michael, Nagase Hiroshi
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] Glioneuronal mechanisms integrating sleep homeostasis and motivation2024
- Author(s)
  Michael Lazarus
- Organizer
  ERATO UK-Japan Joint Symposium on Circadian Rhythms and Sleep
- Invited
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] The Teleological Mystery of Sleep - Glioneuronal Mechanisms Integrating Sleep Homeostasis and Motivation2024
- Author(s)
  Michael Lazarus
- Organizer
  Gordon Research Conference “Sleep Regulation and Function”
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] Glioneuronal mechanisms integrating sleep homeostasis and motivation2023
- Author(s)
  Michael Lazarus
- Organizer
  The 16th Annual Meeting of the Chinese Neuroscience Society & The 2nd CJK International Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] Why are we sleepy when we are bored? The gating of sleep homeostasis by motivation2023
- Author(s)
  Michael Lazarus
- Organizer
  45th Annual Meeting of Japanese Society of Sleep Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] Glioneuronal mechanisms integrating sleep homeostasis and motivation2023
- Author(s)
  Michael Lazarus
- Organizer
  World Sleep 2023 - Congress of the World Sleep Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] Why Are We Sleepy When we are bored? - The Gating of Sleep Homeostasis by Motivation2023
- Author(s)
  Michael Lazarus
- Organizer
  SLEEP 2023 - 37th Meeting of the Associated Sleep Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] The gating of sleep homeostasis by motivation. Why are we sleepy when bored?2021
- Author(s)
  Lazarus Michael
- Organizer
  3rd Congress of the Asian Society of Sleep Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21394
[Presentation] Why are we sleepy when bored? Astroglial regulation of sleep in the nucleus accumbens2020
- Author(s)
  Xuzhao Zhou, Tsuyoshi Saitoh, Zhaofa Wu, Yulong Li, Michael Lazarus
- Organizer
  Cold Spring Harbor Laboratory Meetings - Glia in Health & Disease (Virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] Why are we sleepy when bored? - The gating of sleepiness by motivation2020
- Author(s)
  Michael Lazarus
- Organizer
  International Sleep Medicine Forum (Virtual), Shanghai, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] Why do we fall asleep when bored?The gating of sleep by motivated behaviors2019
- Author(s)
  Lazarus Michael
- Organizer
  NEURO 2019 - The 42nd Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] The brain mechanisms underlying the desire to sleep in boring situations2019
- Author(s)
  Lazarus Michael
- Organizer
  IBRO 2019 - 10th IBRO World Congress of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] Why are we sleepy when bored? Neural circuitry linking sleep and motivation2019
- Author(s)
  Lazarus Michael
- Organizer
  Toyama Forum for Academic Summit on “Dynamic Brain”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] 退屈な時に眠くなるのはなぜ？－脳メカニズムの観点から2019
- Author(s)
  Lazarus Michael
- Organizer
  Senri Life Science Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] The gating of sleep by motivated behavior2018
- Author(s)
  Lazarus Michael
- Organizer
  ESRS 2018 - 24th Congress of the European Sleep Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] The link between REM sleep loss and the desire for junk food2018
- Author(s)
  Lazarus Michael
- Organizer
  FENS 2018 - 11th FENS Forum of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06047
[Presentation] Why do we fall asleep when bored? - The control of sleep and wakefulness by the nucleus accumbens2018
- Author(s)
  Lazarus Michael, Oishi Yo
- Organizer
  Neuroscience 2018 - The 41st Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] The link between REM sleep loss and the desire for sugary and fatty foods2017
- Author(s)
  Lazarus, M
- Organizer
  International Symposium on LIVING IN SPACE 2017
- Place of Presentation
  Hitotsubashi Hall (Chiyoda-ku, Tokyo)
- Year and Date
  2017-03-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04762
[Presentation] The waking, sleeping and dreaming brain: New circuits and insights2017
- Author(s)
  Lazarus Michael, Fuller Patrick
- Organizer
  World Sleep 2017 - 1st Congress of the World Sleep Society
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629
[Presentation] The link between REM sleep loss and the desire for sugary and fatty foods2017
- Author(s)
  Lazarus, M
- Organizer
  International Symposium on Living in Space 2017
- Place of Presentation
  Hitotsubashi Hall (Chiyoda-ku, Tokyo)
- Year and Date
  2017-03-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629
[Presentation] The waking, sleeping and dreaming brain: New circuits and insights2017
- Author(s)
  Lazarus Michael, Fuller Patrick
- Organizer
  World Sleep 2017 - 1st Congress of the World Sleep Society
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06047
[Presentation] The waking, sleeping and dreaming brain: New circuits and insights2017
- Author(s)
  Lazarus Michael, Fuller Patrick
- Organizer
  World Sleep 2017 - 1st Congress of the World Sleep Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] Why do we fall asleep when bored? - The role of the nucleus accumbens in sleep-wake regulation2016
- Author(s)
  Lazarus, M
- Organizer
  23rd Congress of the European Sleep Research Society
- Place of Presentation
  Bologna, Italy
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629
[Presentation] Introduction to Sleep2014
- Author(s)
  Lazarus, Michael
- Organizer
  Tokyo Translational Therapeutics Meeting
- Place of Presentation
  Ito Hall, The University of Tokyo (Tokyo, Bunkyo-ku)
- Year and Date
  2014-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role of adenosine A2A receptors in sleep-wake regulation2013
- Author(s)
  Lazarus M
- Organizer
  The 2013 International Conference on Brain and Health Informatics
- Place of Presentation
  前橋
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role of adenosine A2A receptors in sleep-wake regulation2013
- Author(s)
  Lazarus M
- Organizer
  Tsukuba Global Science Week 2013 ~EXPLORING HUMAN SCIENCES~
- Place of Presentation
  つくば
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2013
- Author(s)
  Lazarus M
- Organizer
  日本睡眠学会第39回定期学術集会
- Place of Presentation
  秋田
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2013
- Author(s)
  Lazarus M
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] What can optogenetics, DREADDs and RNA interference tell us about the role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation?2013
- Author(s)
  Lazarus M
- Organizer
  第90回日本生理学会大会事務局
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Role of the A2A receptors in the nucleus accumbens in sleep-wake regulation2012
- Author(s)
  Lazarus M
- Organizer
  SLEEP 2012-26th Annual Meeting of the Associated Professional Sleep Societies, LLC(APSS)
- Place of Presentation
  ボストン、米国
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Role of the A2A receptors in the nucleus accumbens in sleep-wake regulation2012
- Author(s)
  Lazarus M
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Is there an intrinsic role of adenosine A2A receptors in the nucleus accumbens for sleep wake regulation?2012
- Author(s)
  Lazarus M
- Organizer
  NEUROSCIENCE 2012-42nd Annual Meeting of the Society for Neuroscience (SfN)
- Place of Presentation
  ニューオーリンズ、米国
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2012
- Author(s)
  Lazarus M
- Organizer
  The 7th Congress of Asian Sleep Research Society
- Place of Presentation
  台北、台湾
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] The role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O
- Organizer
  WORLDSLEEP2011-6th Quadrennial Congress of the World Sleep Federation
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of adenosine A_<2A> receptors in the nucleus accumbens for sleep-wake regulation2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  WORLDSLEEP2011-6th Quadrennial Congress of the World Sleep Federation
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2011
- Author(s)
  Lazarus M.
- Organizer
  8th IBRO World Congress of Neuroscience
- Place of Presentation
  フィレンツェ、イタリア
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of the nucleus accumbens in the regulation of behavioral arousal2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  21st World Congress on Psychosomatic Medicine
- Place of Presentation
  ソウル、韓国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Immunohistochemical localization of the vesicular ATP transporter(VNUT) in the rat central nervous system and its role in sleep-wake regulation2010
- Author(s)
  Lazarus M, Hiasa M, Ko Mitamura E, Cherasse Y, Moriyama Y, Urade Y, Hayaishi O.
- Organizer
  Neuroscience 2010【40th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  サンディエゴ、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of extracellular adenosine in the basal ganglia for sleep-wake regulation2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  Neuro2010【第33回日本神経科学大会】
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of the nucleus accumbens shell in the regulation of behavioral arousal2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O
- Organizer
  6th Congress of the Chinese Sleep Research Society
- Place of Presentation
  成都、中国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of prostaglandin D_2 in causing post-ictal sleep following seizures2010
- Author(s)
  Lazarus M, Kaushik MK, Moriyama T, Qu WM, Aritake K, Rahman MA, Huang ZL, Urade Y, Hayaishi O.
- Organizer
  Neuroscience 2010【41th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  ワシントン、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Role of the A_<2A> receptors in the nucleus accumbens in sleep-wake regulation2010
- Author(s)
  Lazarus M.
- Organizer
  SLEEP 2012-26th Annual Meeting of the Associated Professional Sleep Societies, LLC(APSS)
- Place of Presentation
  ボストン、米国(招待講演)
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of extracellular adenosine in the basal ganglia for sleep-wake regulation2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  6th Congress of the Chinese Sleep Research Society
- Place of Presentation
  成都、中国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Immunohistochemical localization of the vesicular ATP transporter(VNUT)in the rat central nervous system and its role in sleep wake regulation2010
- Author(s)
  Lazarus M, Hiasa M, Ko Mitamura E, Cherasse Y, Moriyama Y, Urade Y, Hayaishi O
- Organizer
  Neuroscience 2010【40th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  サンディエゴ、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Dissection of adenosine-responsive sleep circuits by using adeno-associated viral(AAV) vectors for focal RNA interference2009
- Author(s)
  Lazarus, M.
- Organizer
  第6回アジア睡眠学会(ASRS)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Dissection of adenosine-responsive sleep circuits by using adenoassociated viral(AAV)vectors for focal RNA interference2009
- Author(s)
  Lazarus, Michael
- Organizer
  第6回アジア睡眠学会(ASRS)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of adenosine A2A receptors in the nucleus accumbens for the control of sleep and wakefulness
- Author(s)
  Lazarus, Michael
- Organizer
  The 39th Annual Meeting of Japanese Society of Sleep Research
- Place of Presentation
  Hotel CLEMENT Tokushima (Tokushima, Tokushima)
- Year and Date
  2014-07-03 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] The role of the nucleus accumbens in the control of sleep and wakefulness
- Author(s)
  Lazarus, Michael
- Organizer
  The 68th Fujihara Seminar: Homeodynamics in Clock, Sleep and Metabolism
- Place of Presentation
  Amagi Homstead (Shizuoka, Izu)
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] 光遺伝学とDREADDを用いたカエフィンの覚醒作用メカニズムの解明
- Author(s)
  Lazarus, Michael
- Organizer
  Neuroscience 2014 - 37th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Pacifico Yokohama (Kanagawa, Yokohama)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - Role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation
- Author(s)
  Lazarus, Michael
- Organizer
  6th World Congress on Sleep Medicine
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-03-21 – 2015-03-25
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role adenosine A2A receptors in the nucleus accumbens for sleep/wake regulation
- Author(s)
  Lazarus, Michael
- Organizer
  SLEEP 2014 - 28th Annual Meeting of the Associated Professional Sleep Societies, LLC (APSS)
- Place of Presentation
  Minneapolis, USA
- Year and Date
  2014-05-31 – 2014-06-04
- Data Source
  KAKENHI-PROJECT-24300129
[Presentation] Why coffee wakes us up? - The role adenosine A2A receptors in the nucleus accumbens for sleep/wake regulation
- Author(s)
  Lazarus, Michael
- Organizer
  8th Congress of the Chinese Sleep Research Society
- Place of Presentation
  Beijing, China
- Year and Date
  2014-06-13 – 2014-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-24300129

1. URADE Yoshihiro (10201360)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. OISHI Yo (70554004)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. CHERASSE Yoan (60544319)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. TAKATA Yohko (60435740)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. MITAMURA Ko elizabeth (20450249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. URADE Reiko (90167289)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 斉藤毅 (80609933)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. MCEOWN KRISTOPHER

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MATSUMOTO Naomi (60450243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAYAISHI Osamu (40025507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
11. HUANG Zhi-li (10321704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. KASHIWAGI Kahori (10372666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAUSHIK Mahesh (20648274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. MALYSHEVSKAYA Olga (20739429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Nagata Nanae (80390805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 柳沢正史 (20202369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 阿部高志 (00549644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 本城咲季子 (30551379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 林悠 (40525812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 史蕭逸 (40803656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 桜井武 (60251055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 坂口昌徳 (60407088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 坪田有沙 (60806230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Vogt Kaspar (80740034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Higashino Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Natsusaki Motonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Okuda Aya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FIFEL KARIM

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. FUNATO Hiromasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. HIKIDA Takatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. KANBE Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 有竹浩介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 大日向耕作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. ROY Koustav

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Lazarus Michael ラザルス ミハエル

LAZARUS Michael ラザルス ミハエル

LAZARUS Michae ラザルス ミハイル

Research Projects

Research Products

Co-Researchers

Gliosomnia and immunity: decoding brain-immune interactions in sleepPrincipal Investigator

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Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists

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Understanding the mechanism of sleepiness by exploring mesolimbic glia-neuron interactionsPrincipal Investigator

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WillDynamics of REM sleep and appetitePrincipal Investigator

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Risk of hypothermia for memory functionPrincipal Investigator

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Neuronal mechanisms of sleep alterations in Parkinson's Disease: A circuit based investigationPrincipal Investigator

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Will-dynamics of REM sleep and appetitePrincipal Investigator

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The role of the nucleus accumbens in regulating slow-wave sleep by motivated behaviorPrincipal Investigator

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Risk of hypothermia for memory functionPrincipal Investigator

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Development of a mouse model of chronic sleep loss to elucidate the mechanism of metabolic disorder

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睡眠が認知機能の柔軟性および情動の調節に与える影響の解明Principal Investigator

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Functional analysis of ER-60, an ER chaperone by gene mamipulation and crystal structure analysis

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Identification of a striatopallidal pathway facilitating sleep and wakefulnessPrincipal Investigator

Principal Investigator

Project Period (FY)

Lazarus Michael ラザルスミハエル

LAZARUS Michael ラザルスミハエル

LAZARUS Michae ラザルスミハイル