Horinaka Mano 堀中真野

… Alternative Names

TOMOSUGI Mano 友杉真野

堀中真野

HORINAKA Mano 堀中真野

友杉真野(堀中真野) トモスギマノ

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Researcher Number	80512037
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2014 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2015: 京都府立医科大学, 医学研究科, 講師 2011 – 2013: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2008 – 2012: Kyoto Prefectural University of Medicine, 医学研究科, 助教 2011: 京都府立医科大学, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health / Medium-sized Section 58:Society medicine, nursing, and related fields / Society medicine, Nursing, and related fields Except Principal Investigator Hygiene / Medium-sized Section 58:Society medicine, nursing, and related fields / Hygiene and public health / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 38:Agricultural chemistry and related fields / Complex systems / Biological Sciences
Keywords	Principal Investigator TRAIL / 予防 / がん予防 / がん / RB / アポトーシス / 癌 / 糖尿病 / 癌予防 / 免疫 … More / DR5 / microRNA / 膵NET / MEN1 / 先制医療 / ヒ素 / 動脈硬化 / NSAIDs / 大腸がん / 分子予防 / 分子標的併用予防 / マトリックスメタロプロテアーゼ / 併用 / タンパク質分泌機構 / p^<53> / アボトーシス / 食品成分 / p53 … More Except Principal Investigator TRAIL / がん予防 / アポトーシス / 併用 / がん / p53 / 癌 / 先制医療 / 予防 / 分子予防 / 天然物 / 喫煙 / 大腸がん / HDAC阻害剤 / リ・フラウメニ症候群 / DR5 / RB / ヒストン脱アセチル化酵素(HDAC)阻害剤 / 骨肉腫 / 生物間相互作用 / 毒の蓄積 / ヘビの防御物質 / ブファジエノライド / 生物環相互作用 / Eomes / T-bet / IL-6 / 細胞老化 / NK細胞 / ケミカルバイオロジー / スクリーニング / SASP / 家族性大腸腺腫症 / がん体質診断 / テーラーメイドがん予防 / 化学予防 / アスピリン / 免疫 / タバコ成分 / がん細胞死 / 抗酸化能 / 飲料 / 抗炎症 / 抗酸化 / RB再活性化 / 分子標的予防法 / HDAC阻害作用 / 酪酸 / グルタチオン / Reactive oxygen species(ROS) / ミトコンドリア / Reactive oxygen species (ROS) / DNAメチル化 / HDAC 阻害剤 / microRNA / DNA メチル化 / 悪性中皮腫 / miR-16 / miR-15 / Bcl-2 / プロモーター / miR-222 / miR-221 / miR-34b/c / メチル化 / flavone / フラボノイド / G1期停止 / E2F / G1 期停止 / miR-34a / フラボン / TPA / p18 / Oct-1 / MEK / MAPK / p15 / 家族性メラノーマ / p53-RB経路 / p16 / テーラーメイド予防 / 癌抑制遺伝子 Less

Development of novel molecular target combination therapy for osteosarcoma
- Principal Investigator
  
  村田博昭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of preemptive medical care for pre-symptomatic MEN1 gene mutation carriersPrincipal Investigator
- Principal Investigator
  
  堀中真野
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Development of preemptive medicine against RB-mutated malignancies
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Bufadienolides, a snake defense substance: Investigation of the mechanism of dietary evolution.
- Principal Investigator
  
  森直樹
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Basic research for prevention of arteriosclerosis by cancer preventive ingredients with RB activation abilityPrincipal Investigator
- Principal Investigator
  
  Tomosugi (Horinaka) Mano
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Tailor-maid cancer prevention towards the era of preemptive medicine.
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Preventive strategy against arsenic carcinogenesis by TRAIL pathway activation and RB activationPrincipal Investigator
- Principal Investigator
  
  Horinaka Mano
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
A new colorectal cancer chemoprevention method to reduce side effects of aspirin
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Study of the COX-independent mechanisms in the efficacy of prevention for colon carcinogenesis by NSAIDsPrincipal Investigator
- Principal Investigator
  
  TOMOSUGI (HORINAKA) Mano
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Research of molecular-targeting prevention against inflammatory diseases using chemical biology.
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Prefectural University of Medicine
Study of the mechanism of cancer-risk increase due to diabetes and suggestion of the molecular-targeting cancer prevention for the cancerPrincipal Investigator
- Principal Investigator
  
  TOMOSUGI (HORINAKA) Mano
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of mechanism of exacerbation by smoking in intervention study for cancer prevention
- Principal Investigator
  
  MASUDA Mitsuharu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Application of molecular-targeting cancer prevention to human intervention study.
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the novel mechanisms of carcinogenesis induced by the cigarette and development of cancer prevention for carcinogenesis by sidestream smoke
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the molecular targeting cancer prevention for diabetics by the activation of TRAIL pathway.Principal Investigator
- Principal Investigator
  
  Tomosugi(Horinaka) Mano
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Novel molecular-targeting prevention of cancer by inducers of MMP-8 releasePrincipal Investigator
- Principal Investigator
  
  TOMOSUGI Mano (HORINAKA Mano)
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
"Combination-oriented molecular-targeting prevention" of cancer via the activation of TRAIL pathway by targeting microRNA.Principal Investigator
- Principal Investigator
  
  Tomosugi(Horinaka) Mano
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Novel molecular-targeting prevention of cancer by sensitizing the effect of sodium butyrate
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Novel molecular-targeting prevention of cancer by inducers of TRAIL releasePrincipal Investigator
- Principal Investigator
  
  TOMOSUGI Mano (HORINAKA Mano)
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of micrRNA-targeting cancer prevention
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of cancer prevention based on the molecular mechanism against malignant mesothelioma.
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
TRAILとDR5を標的とした癌の「分子標的併用療法」の開発
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
Combination-oriented molecular-targeting prevention of cancer : targeting TRAIL and microRNA.Principal Investigator
- Principal Investigator
  
  HORINAKA Mano
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine

[Journal Article] Effects of combined therapeutic targeting of AXL and ATR on pleural mesothelioma cells2024
- Author(s)
  Hirai S, Yamada T, Katayama Y, Ishida M, Kawachi H, Matsui Y, Nakamura R, Morimoto K, Horinaka M, Sakai T, Sekido Y, Tokuda S, Takayama K
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 23 Issue: 2 Pages: 212-222
- DOI
  10.1158/1535-7163.mct-23-0138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-23K07607, KAKENHI-PROJECT-21K15513, KAKENHI-PROJECT-19H01079
[Journal Article] Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells2024
- Author(s)
  Ota Y, Itoh Y, Takada Y, Yamashita Y, Hu C, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 100 Pages: 117632-117632
- DOI
  10.1016/j.bmc.2024.117632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795
[Journal Article] Adaptive resistance to lorlatinib via EGFR signaling in ALK-rearranged lung cancer2023
- Author(s)
  Katayama Y, Yamada T, Tanimura K, Tokuda S, Morimoto K, Hirai S, Matsui Y, Nakamura R, Ishida M, Kawachi H, Yoneda K, Hosoya K, Tsuji T, Ozasa H, Yoshimura A, Iwasaku M, Kim YH, Horinaka M, Sakai T, Utsumi T, Shiotsu S, Takeda T, Katayama R, Takayama K
- Journal Title
  
  npj Precision Oncology
  
  Volume: 7 Issue: 1 Pages: 12-12
- DOI
  10.1038/s41698-023-00350-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-22K18383
[Journal Article] Identification of c-Met as a novel target of γ-glutamylcyclotransferase2023
- Author(s)
  Saito Y, Taniguchi K, Ii H, Horinaka M, Kageyama S, Nakata S, Ukimura O, Sakai T
- Journal Title
  
  Sci Rep
  
  Volume: 13 Issue: 1 Pages: 11922-11922
- DOI
  10.1038/s41598-023-39093-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-22K17350, KAKENHI-PROJECT-22K06756, KAKENHI-PROJECT-23K06642, KAKENHI-PROJECT-21K09342, KAKENHI-PROJECT-19H01079
[Journal Article] Discovery of cancer-preventive juices reactivating RB functions2023
- Author(s)
  Masuda M, Horinaka M, Yasuda S, Morita M, Nishimoto E, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 28 Issue: 0 Pages: 54-54
- DOI
  10.1265/ehpm.23-00160
- ISSN
  1342-078X, 1347-4715
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-23K27841
[Journal Article] The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma.2022
- Author(s)
  Isa R, Horinaka M, Tsukamoto T, Mizuhara K, Fujibayashi Y, Taminishi-Katsuragawa Y, Okamoto H, Yasuda S, Kawaji-Kanayama Y, Matsumura-Kimoto Y, Mizutani S, Shimura Y, Taniwaki M, Sakai T, Kuroda J.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 6 Pages: 2919-2936
- DOI
  10.3390/ijms23062919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08872, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-21K16246, KAKENHI-PROJECT-21K16274
[Journal Article] Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients2022
- Author(s)
  Mure Kanae、Ishikawa Hideki、Mutoh Michihiro、Horinaka Mano、Otani Takahiro et al.
- Journal Title
  
  Cancer Research Communications
  
  Volume: 2 Issue: 6 Pages: 483-488
- DOI
  10.1158/2767-9764.crc-22-0088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11791, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Citrus limon L.-Derived Nanovesicles Show an Inhibitory Effect on Cell Growth in p53-Inactivated Colorectal Cancer Cells via the Macropinocytosis Pathway2022
- Author(s)
  Takakura Hideki、Nakao Toshimasa、Narita Takumi、Horinaka Mano、Nakao-Ise Yukako、Yamamoto Tetsushi、Iizumi Yosuke、Watanabe Motoki、Sowa Yoshihiro、Oda Keisuke、Mori Nobuhiro、Sakai Toshiyuki、Mutoh Michihiro
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 6 Pages: 1352-1352
- DOI
  10.3390/biomedicines10061352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10489, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Cancer-cell-selective targeting by arylcyclopropylamine-vorinostat conjugates2022
- Author(s)
  Ota Y, Itoh Y, Kurohara T, Singh R, Elboray EE, Hu C, Zamani F, Mukherjee A, Takada Y, Yamashita Y, Morita M, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 13 Issue: 10 Pages: 1568-1573
- DOI
  10.1021/acsmedchemlett.2c00126
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20F40107, KAKENHI-PROJECT-21K20719
[Journal Article] Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR-T790M mutation in non-small cell lung cancer cells2022
- Author(s)
  Katayama Y, Yamada T, Tokuda S, Okura N, Nishioka N, Morimoto K, Tanimura K, Morimoto Y, Iwasaku M, Horinaka M, Sakai T, Kita K, Yano S, Takayama K
- Journal Title
  
  Cancer Medicine
  
  Volume: 11 Issue: 4 Pages: 944-955
- DOI
  10.1002/cam4.4504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-21K15513
[Journal Article] Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells2022
- Author(s)
  Takakura H, Horinaka M, Imai A, Aono Y, Nakao T, Miyamoto S, Iizumi Y, Watanabe M, Narita T, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 2 Pages: 93-102
- DOI
  10.3164/jcbn.21-74
- NAID
  130008165971
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features.2022
- Author(s)
  Tanimura K, Yamada T, Okada K, Nakai K, Horinaka M, Katayama Y, Morimoto K, Ogura Y, Takeda T, Shiotsu S, Ichikawa K, Watanabe S, Morimoto Y, Iwasaku M, Kaneko Y, Uchino J, Taniguchi H, Yoneda K, Matoba S, Sakai T, Uehara H, Yano S, Kusaba T, Katayama R, Takayama K.
- Journal Title
  
  NPJ Precis Oncol.
  
  Volume: 6 Issue: 1 Pages: 5-5
- DOI
  10.1038/s41698-021-00250-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08608, KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K22820, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K08640
[Journal Article] Oridonin inhibits SASP by blocking p38 and NF-κB pathways in senescent cells2022
- Author(s)
  Yasuda Shusuke、Horinaka Mano、Iizumi Yosuke、Goi Wakana、Sukeno Mamiko、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 55-62
- DOI
  10.1016/j.bbrc.2021.12.098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells2022
- Author(s)
  Imai A, Horinaka M, Aono Y, Iizumi Y, Takakura H, Ono H, Yasuda S, Taniguchi K, Nishimoto E, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 628 Pages: 110-115
- DOI
  10.1016/j.bbrc.2022.08.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-22K17350, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Inhibition of c-Jun N-terminal kinase signaling increased apoptosis and prevented the emergence of ALK-TKI-tolerant cells in ALK-rearranged non-small cell lung cancer.2021
- Author(s)
  Tanimura K, Yamada T, Horinaka M, Katayama Y, Fukui S, Morimoto K, Nakano T, Tokuda S, Morimoto Y, Iwasaku M, Kaneko Y, Uchino J, Yoneda K, Yano S, Sakai T, Takayama K.
- Journal Title
  
  Cancer Lett.
  
  Volume: 522 Pages: 119-128
- DOI
  10.1016/j.canlet.2021.09.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08608, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis2021
- Author(s)
  Taniguchi Keiko、Kageyama Susumu、Moyama Chiami、Ando Shota、Ii Hiromi、Ashihara Eishi、Horinaka Mano、Sakai Toshiyuki、Kubota Shigehisa、Kawauchi Akihiro、Nakata Susumu
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: - Issue: 1 Pages: 37-48
- DOI
  10.1038/s41417-020-00287-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07623, KAKENHI-PROJECT-20K23233, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773, KAKENHI-PROJECT-21K09342
[Journal Article] The combination of cigarette smoking and alcohol consumption synergistically increases reactive carbonyl species in human male plasma2021
- Author(s)
  Mure K, Tomono S, Mure M, Horinaka M, Mutoh M, Sakai T, Ishikawa H, Wakabayashi K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 9043-9043
- DOI
  10.3390/ijms22169043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K11635, KAKENHI-PROJECT-21K18291, KAKENHI-PROJECT-18H03054
[Journal Article] Novel RAF/MEK inhibitor CH5126766/VS‐6766 has efficacy in combination with eribulin for the treatment of triple‐negative breast cancer2021
- Author(s)
  Ono H, Horinaka M, Sukeno M, Morita M, Yasuda S, Nishimoto E, Konishi E, Sakai T
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 4166-4175
- DOI
  10.1111/cas.15071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K18906
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03889
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON.
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non?Small Cell Lung Cancer2020
- Author(s)
  Okura N, Nishioka N, Yamada T, Taniguchi H, Tanimura K, Katayama Y, Yoshimura A, Watanabe S, Kikuchi T, Shiotsu S, Kitazaki T, Nishiyama A, Iwasaku M, Kaneko Y, Uchino J, Uehara H, Horinaka M, Sakai T, Tanaka K, Kozaki R, Yano S, Takayama K.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 26 Issue: 9 Pages: 2244-2256
- DOI
  10.1158/1078-0432.ccr-19-2321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0019, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19K08608, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-23K20323
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON.
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Histone deacetylase inhibitor OBP-801 and amrubicin synergistically inhibit the growth of squamous cell lung carcinoma by inducing mitochondrial ASK1-dependent apoptosis.2020
- Author(s)
  Chihara Y, Iizumi Y, Horinaka M, Watanabe M, Goi W, Morita M, Nishimoto E, Sowa Y, Yamada T, Takayama K, Sakai T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 56 Pages: 848-856
- DOI
  10.3892/ijo.2020.4969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773
[Journal Article] Sulforaphane enhances apoptosis induced by Lactobacillus pentosus strain S-PT84 via the TNFα pathway in human colon cancer cells.2019
- Author(s)
  Yasuda S, Horinaka M, Sakai T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 18 Pages: 4253-4261
- DOI
  10.3892/ol.2019.10739
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 22018
- Author(s)
  Aono Yuichi、Horinaka Mano、Iizumi Yosuke、Watanabe Motoki、Taniguchi Tomoyuki、Yasuda Shusuke、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 4 Pages: 1203-1210
- DOI
  10.1016/j.bbrc.2018.10.050
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-16H05260, KAKENHI-PROJECT-17K19829
[Journal Article] FGFR inhibitor BGJ398 and HDAC inhibitor OBP-801 synergistically inhibit cell growth and induce apoptosis in bladder cancer cells.2018
- Author(s)
  Takamura T, Horinaka M, Yasuda S, Toriyama S, Aono Y, Sowa Y, Miki T, Ukimura O, Sakai T.
- Journal Title
  
  Oncology Reports
  
  Volume: 39 Pages: 627-632
- DOI
  10.3892/or.2017.6127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05260
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2.2018
- Author(s)
  Aono Y, Horinaka M, Iizumi Y, Watanabe M, Taniguchi T, Yasuda S, Sakai T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Pages: 1203-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02529
[Journal Article] Mevalonate pathway blockage enhances the efficacy of mTOR inhibitors with the activation of retinoblastoma protein in renal cell carcinoma2018
- Author(s)
  Hagiwara Nobuhisa、Watanabe Motoki、Iizuka-Ohashi Mahiro、Yokota Isao、Toriyama Seijiro、Sukeno Mamiko、Tomosugi Mitsuhiro、Sowa Yoshihiro、Hongo Fumiya、Mikami Kazuya、Soh Jintetsu、Fujito Akira、Miyashita Hiroaki、Morioka Yukako、Miki Tsuneharu、Ukimura Osamu、Sakai Toshiyuki
- Journal Title
  
  Cancer Letters
  
  Volume: 431 Pages: 182-189
- DOI
  10.1016/j.canlet.2018.05.025
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] The histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth of triple-negative breast cancer cells with the suppression of survivin, Bcl-xL, and the MAPK pathway.2018
- Author(s)
  Ono H, Sowa Y, Horinaka M, Iizumi Y, Watanabe M, Morita M, Nishimoto E, Taguchi T, Sakai T.
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 171 Issue: 1 Pages: 43-52
- DOI
  10.1007/s10549-018-4815-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05260
[Journal Article] Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells.2015
- Author(s)
  Ryoichi Tanaka, Mitsuhiro Tomosugi, Mano Horinaka, Yoshihiro Sowa, Toshiyuki Sakai.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e0125779-e0125779
- DOI
  10.1371/journal.pone.0125779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670336, KAKENHI-PROJECT-24689031
[Journal Article] Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells.2014
- Author(s)
  Horinaka M, Yoshida T, Tomosugi M, Yasuda S, Sowa Y, Sakai T.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 6000-6000
- DOI
  10.1038/srep06000
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24689031, KAKENHI-PROJECT-26460792
[Journal Article] Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8.2013
- Author(s)
  Masahide Shinnoh, Mano Horinaka, Takashi Yasuda, Sae Yoshikawa, Mie Morita, Takeshi Yamada, Tsuneharu Miki, Toshiyuki Sakai
- Journal Title
  
  International Journal of Oncology
  
  Volume: 42 Issue: 3 Pages: 903-911
- DOI
  10.3892/ijo.2013.1790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24659304
[Journal Article] Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation.2013
- Author(s)
  Todo M, Horinaka M, Tomosugi M, Tanaka R, Ikawa H, Sowa Y, Ishikawa H, Fujiwara H, Otsuji E, Sakai T
- Journal Title
  
  Oncol Rep.
  
  Volume: 30 Issue: 5 Pages: 2379-2384
- DOI
  10.3892/or.2013.2713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591958, KAKENHI-PROJECT-24659304, KAKENHI-PROJECT-24689031
[Journal Article] Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic molecules2012
- Author(s)
  Hiroya Taniguchi, Mano Horinaka, Tatsushi Yoshida, Kimihiro Yano, Ahmed E Goda, Shusuke Yasuda, Miki Wakada, Toshiyuki Sakai.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11 Pages: 2294-2294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336
[Journal Article] Retinoblastoma gene-independent G1 phase arrest by flavone, phosphatidylinositol 3-kinase inhibitor, and histone deacetylase inhibitor2012
- Author(s)
  Tomosugi M, Sowa Y, Yasuda S, Tanaka R, te Riele H, Ikawa H, Koyama M, Sakai T
- Journal Title
  
  Cancer Sci.
  
  Volume: Vol. 103、 No. 12 Issue: 12 Pages: 2139-2143
- DOI
  10.1111/cas.12012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790670, KAKENHI-PROJECT-24591958
[Journal Article] Aclarubicin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through death receptor 5 upregulation.2012
- Author(s)
  Mano Horinaka, Tatsushi Yoshida, Susumu Nakata, Takumi Shiraishi, Mitsuhiro Tomosugi, Sae Yoshikawa, Miki Wakada, Toshiyuki Sakai
- Journal Title
  
  Cancer Science
  
  Volume: 103 Issue: 2 Pages: 282-287
- DOI
  10.1111/j.1349-7006.2011.02150.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-23791491
[Journal Article] Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic molecules.2012
- Author(s)
  Hiroya Taniguchi, Mano Horinaka, Tatsushi Yoshida, Kimihiro Yano, Ahmed E Goda, Shusuke Yasuda, Miki Wakada, Toshiyuki Sakai
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11 Pages: 2294-2300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336
[Journal Article] The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells.2012
- Author(s)
  Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai
- Journal Title
  
  International Journal of Oncology
  
  Volume: 40 Pages: 1483-1491
- DOI
  10.3892/ijo.2012.1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24591958
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells.2010
- Author(s)
  Horinaka M, et al.
- Journal Title
  
  FEBS letters 584(3)
  
  Pages: 577-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015040
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells.2010
- Author(s)
  Horinaka M., et al.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 577-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells2010
- Author(s)
  Horinaka M, Yoshida T, Kishi A, Akatani K, Yasuda T, Kouhara J, Wakada M, Sakai T
- Journal Title
  
  FEBS Lett
  
  Volume: Vol. 584、 No. 3 Issue: 3 Pages: 577-82
- DOI
  10.1016/j.febslet.2009.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells.2010
- Author(s)
  Horinaka M, et al.
- Journal Title
  
  FEBS letters 584(3)
  
  Pages: 577-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells.2010
- Author(s)
  Horinaka M, Yoshida T, Kishi A, Akatani K, Yasuda T, Kouhara J, Wakada M, Sakai T.
- Journal Title
  
  FEBS Letters 584
  
  Pages: 577-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-・12,14-prostaglandin J2 synergistically induce apoptosis2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T
- Journal Title
  
  Clin Cancer Res.
  
  Volume: Vol. 16、No. 8 Issue: 8 Pages: 2320-2332
- DOI
  10.1158/1078-0432.ccr-09-2301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole.2008
- Author(s)
  Goda AE, Yoshida T, Horinaka M, Yasuda T, Shiraishi T, Wakada M, Sakai T.
- Journal Title
  
  Oncogene 27
  
  Pages: 3435-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Baicalein overcomes TRAIL resistance via two different cell specific pathways in cancer cells but not in normal cells2008
- Author(s)
  Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T
- Journal Title
  
  Cancer Res. 68
  
  Pages: 8918-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis.2008
- Author(s)
  Yoshida T, Konishi M, Horinaka M, Yasuda T, Goda AE, Taniguchi H, Yano K, Wakada M, Sakai T.
- Journal Title
  
  Biochem Biophys Res Commun 375
  
  Pages: 129-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Baicalein overcomes TRAIL resistance via two different cell specific pathways in cancer cells but not in normal cells.2008
- Author(s)
  Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T.
- Journal Title
  
  Cancer Res 68
  
  Pages: 8918-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.2008
- Author(s)
  Yoshida T, Horinaka M, Takara M, Tsuchihashi M, Mukai N, Wakada M, Sakai T.
- Journal Title
  
  Environmental Health and Preventive Medicine 13
  
  Pages: 281-7
- NAID
  10026957710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] 食品成分による癌の「分子標的予防法」の開発2008
- Author(s)
  堀中真野、酒井敏行
- Journal Title
  
  FFIジャーナル 213
  
  Pages: 537-44
- NAID
  40016121757
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with TRAIL2008
- Author(s)
  Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Mol Cancer Res 6
  
  Pages: 1852-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with TRAIL.2008
- Author(s)
  Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T.
- Journal Title
  
  Mol Cancer Res 6
  
  Pages: 1852-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] 食品成分による癌の「分子標的予防法」の開発2008
- Author(s)
  堀中真野, 他
- Journal Title
  
  FFIジャーナル 213(6)
  
  Pages: 537-544
- NAID
  40016121757
- Data Source
  KAKENHI-PROJECT-20015040
[Journal Article] 食品成分による癌の「分子標的予防法」の開発2008
- Author(s)
  堀中真野, 他
- Journal Title
  
  FFIジャーナル 213(6)
  
  Pages: 537-544
- NAID
  40016121757
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis2008
- Author(s)
  Yoshida T, Konishi M, Horinaka M, Yasuda T, Goda AE, Taniguchi H, Yano K, Wakada M, Sakai T
- Journal Title
  
  Biochem Biophys Res Commun. 375
  
  Pages: 129-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole2008
- Author(s)
  Goda AE, Yoshida T, Horinaka M, Yasuda T, Shiraishi T, Wakada M, Sakai T
- Journal Title
  
  Oncogene. 27
  
  Pages: 3455-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells2008
- Author(s)
  Yoshida T, Horinaka M, Takara M, Tsuchihashi M, Mukai N, Wakada M, Sakai T
- Journal Title
  
  Environ Health Prev Med. 13
  
  Pages: 281-7
- NAID
  10026957710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 食品成分による癌の「分子標的予防法」の開発2008
- Author(s)
  堀中真野, 他
- Journal Title
  
  FFIジャーナル 213(6)
  
  Pages: 537-544
- NAID
  40016121757
- Data Source
  KAKENHI-PROJECT-20890191
[Journal Article] Halocynthiaxanthin and peridinin, two dietary carotenoids, sensitize colon cancer cell lines to the death ligand TRAIL2007
- Author(s)
  Yoshida T, Maoka T, Das SK, Kanazawa K, Horinaka M, Wakada M, Satomi, Y, Nishino H, Sakai T
- Journal Title
  
  Mol Cancer Res. 5
  
  Pages: 615-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Glycosylation modulates TRAIL-R1/death receptor 4 protein : different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin2007
- Author(s)
  Yoshida T, Shiraishi T, Horinaka M, Wakada M, Sakai T
- Journal Title
  
  Oncol Rep. 18
  
  Pages: 1239-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines2007
- Author(s)
  Kouhara J, Yoshida T, Nakata S, Horinaka M, Wakada M, Ueda Y, Yamagishi H, Sakai T
- Journal Title
  
  Int J Oncol. 30
  
  Pages: 679-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis2007
- Author(s)
  Yoshida T, Shiraishi T, Horinaka M, Nakata S, Yasuda T, Goda AE, Wakada M, Mizutani Y, Miki T, Nishikawa A, Sakai T
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1417-23
- NAID
  10019998746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 15-Deoxy-Δ^<12, 14>-prostaglandin J_2 induces death receptor 5 expression through mRNA stabilization independently of PPARγ and potentiates TRAIL-induced apoptosis2006
- Author(s)
  Nakata S, Yoshida T, Shiraishi T, Horinaka M, Kouhara J, Wakada M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 5
  
  Pages: 1827-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand2006
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 5
  
  Pages: 945-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells2006
- Author(s)
  Matsui TA, Sowa Y, Yoshida T, Murata H, Horinaka M, Wakada M, Nakanishi R, Sakabe T, Kubo T, Sakai T
- Journal Title
  
  Carcinogenesis. 27
  
  Pages: 1768-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Quercetin induces gadd45 expression through a p53-independent pathway2005
- Author(s)
  Yoshida T, Maeda A, Horinaka M, Shiraishi T, Nakata S, Wakada M, Yogosawa S, Sakai T
- Journal Title
  
  Oncol Rep. 14
  
  Pages: 1299-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells.2005
- Author(s)
  Horinaka M et al.
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 833-838
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein2005
- Author(s)
  Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Cancer Res. 65
  
  Pages: 5662-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells2005
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Nakanishi R, Nishino H, Sakai T
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 833-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Tunicamycin enhances TRAIL-induced apoptosis in human prostate cancer cells2005
- Author(s)
  Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Cancer Res. 65
  
  Pages: 6364-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Differential response at the hGABP/E4TF1 site of retinoblastoma gene promoter in human testicular seminoma cells2005
- Author(s)
  Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Oncol Rep. 13
  
  Pages: 871-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Luteolin induces apoptosis via death receptor 5 up-regulation in human malignant tumor cells2005
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Nakanishi R, Nishino H, Matsui H, Sakai T
- Journal Title
  
  Oncogene. 24
  
  Pages: 7180-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Luteolin induces apoptosis via death receptor 5 up-regulation in human malignant tumor cells.2005
- Author(s)
  Horinaka M et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 7180-7189
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand.
- Author(s)
  Horinaka M et al.
- Journal Title
  
  Mol Cancer Ther (印刷中)
- Data Source
  KAKENHI-PROJECT-17209022
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井敏行、堀中真野、増田光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井　敏行、堀中　真野、増田　光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井　敏行、堀中　真野、増田　光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PLANNED-17H06398
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井敏行、堀中真野、増田光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] GGCTの阻害は、AMPK-STAT3-c-Met経路の抑制を介してがん抑制遺伝子RBを活性化する2024
- Author(s)
  谷口恵香, 齋藤友充子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTの阻害はc-Met発現低下を介してがん細胞の増殖を抑制する2024
- Author(s)
  谷口恵香, 齋藤友允子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] GGCTの阻害は、AMPK-STAT3-c-Met経路の抑制を介してがん抑制遺伝子RBを活性化する2024
- Author(s)
  谷口恵香, 齋藤友充子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ヤマカガシ ( Rhabdophis tigrinus) の毒による子孫への化学的ケアー2024
- Author(s)
  井上貴斗、森哲、堀中真野、吉永直子、酒井敏行、森直樹
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-21H04714
[Presentation] 新規がん予防標的GGCTの阻害はc-Met発現低下を介してがん細胞の増殖を抑制する2024
- Author(s)
  谷口恵香, 齋藤友允子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 悪性胸膜中皮腫におけるATR阻害薬とAXL阻害薬併用治療の検討2023
- Author(s)
  平井聡一, 片山勇輝, 堀中真野, 酒井敏行, 関戸好孝, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET融合遺伝子陽性がんにおけるHER3シグナル活性化を介した初期治療抵抗性機構の解明2023
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] Identification of c-Met as a novel target of γ-glutamylcyclotrasnferase in a prostate cancer cell line2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] KRAS-12C陽性肺がんにおけるAXLの活性化を介したKRAS-G12C阻害薬初期治療抵抗性2023
- Author(s)
  森本健司, 山田忠明, 平井聡一, 片山勇輝, 矢野聖二, 堀中真野, 酒井敏行, 徳田深作, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的γ-グルタミルシクロトランスフェラーゼの阻害は、c-Met発現低下を介してがん細胞の増殖を抑制する2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  がん予防学術大会2023金沢（第30回日本がん予防学会)
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET融合遺伝子陽性がんにおけるHER3シグナル活性化を介した初期治療抵抗性機構の解明2023
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET変異がんにおけるHER3活性化を介したセルペルカチニブに対する治療抵抗性に関する基礎的検討2023
- Author(s)
  片山勇輝, 山田忠明, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的γ-グルタミルシクロトランスフェラーゼの阻害は、c-Met発現低下を介してがん細胞の増殖を抑制する2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  がん予防学術大会2023金沢（第30回日本がん予防学会)
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RET変異がんにおけるHER3活性化を介したセルペルカチニブに対する治療抵抗性に関する基礎的検討2023
- Author(s)
  片山勇輝, 山田忠明, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] KRAS-12C陽性肺がんにおけるAXLの活性化を介したKRAS-G12C阻害薬初期治療抵抗性2023
- Author(s)
  森本健司, 山田忠明, 平井聡一, 片山勇輝, 矢野聖二, 堀中真野, 酒井敏行, 徳田深作, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Identification of c-Met as a novel target of γ-glutamylcyclotrasnferase in a prostate cancer cell line2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 悪性胸膜中皮腫におけるATR阻害薬とAXL阻害薬併用治療の検討2023
- Author(s)
  平井聡一, 片山勇輝, 堀中真野, 酒井敏行, 関戸好孝, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 延命草成分オリドニンはp38とNF-kBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回　日本衛生学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野，酒井敏行
- Organizer
  第91回　日本衛生学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1 alpha発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] アスピリン、メサラジン併用による大腸がん予防効果の検討2020
- Author(s)
  高倉英樹，堀中真野，今井綾香，武藤倫弘，酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんの初期治療抵抗性機構の解明とその克服法の開発2020
- Author(s)
  谷村恵子, 山田忠明, 岡田康太郎, 米田和恵, 堀中真野, 酒井敏行, 矢野聖二, 片山量平
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ONO-7475, a novel AXL inhibitor, suppresses the adaptive resistance to initial EGFR-TKI treatment in EGFR-mutated NSCLC.2020
- Author(s)
  大倉直子, 谷口寛和, 谷村恵子, 堀中真野, 酒井敏行, 田中昴平, 小崎龍平, 矢野聖二, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ONO-7475, a novel AXL inhibitor, suppresses the adaptive resistance to initial EGFR-TKI treatment in EGFR-mutated NSCLC.2020
- Author(s)
  大倉直子, 谷口寛和, 谷村恵子, 堀中真野, 酒井敏行, 田中昴平, 小崎龍平, 矢野聖二, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR遺伝子変異陽性肺がんの初期治療抵抗性に対する新規AXL阻害薬ONO-7475の効果2020
- Author(s)
  大倉直子, 西岡直哉, 谷村恵子, 矢野聖二, 小崎龍平, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR遺伝子変異陽性肺がんの初期治療抵抗性に対する新規AXL阻害薬ONO-7475の効果2020
- Author(s)
  大倉直子, 西岡直哉, 谷村恵子, 矢野聖二, 小崎龍平, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] BRCAness誘導分子の探索2020
- Author(s)
  小野寿子, 堀中真野, 酒井敏行
- Organizer
  第65回日本人類遺伝学会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] アスピリン、メサラジン併用による大腸がん予防効果の検討2020
- Author(s)
  高倉英樹，堀中真野，今井綾香，武藤倫弘，酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19693
[Presentation] ALK融合遺伝子陽性肺がんの初期治療抵抗性機構の解明とその克服法の開発2020
- Author(s)
  谷村恵子, 山田忠明, 岡田康太郎, 米田和恵, 堀中真野, 酒井敏行, 矢野聖二, 片山量平
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] HER3 is a potent therapeutic target for prevention of tolerant cells to ALK inhibitors in ALK-rearranged cancer．2020
- Author(s)
  谷村恵子, 米田和恵, 矢野聖二, 堀中真野, 酒井敏行, 片山量平, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] BRCAness誘導分子の探索2020
- Author(s)
  小野寿子, 堀中真野, 酒井敏行
- Organizer
  第65回日本人類遺伝学会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] HER3 is a potent therapeutic target for prevention of tolerant cells to ALK inhibitors in ALK-rearranged cancer.2020
- Author(s)
  谷村恵子, 米田和恵, 矢野聖二, 堀中真野, 酒井敏行, 片山量平, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] スリンダク代謝体の大腸腺腫形成抑制作用における新規標的分子の探索と作用機序の解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行.
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19829
[Presentation] 新規スリンダクスルホン結合タンパク質VDACによる細胞周期制御のメカニズムの解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第18回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] スリンダク代謝体の大腸腺腫形成抑制作用における新規標的分子の探索と作用機序の解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] スリンダク代謝体であるスリンダクスルホンによる大腸腺腫形成抑制作用の機序解明に向けた新規標的分子の同定2019
- Author(s)
  堀中真野，青野裕一，飯泉陽介，安田周祐，渡邉元樹，谷口知行，酒井敏行
- Organizer
  第26回日本がん予防学会総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] スリンダク代謝体スリンダクスルホンの大腸癌細胞に対する新規標的分子の同定と作用機序の解析2019
- Author(s)
  堀中真野，青野裕一，飯泉陽介，渡邉元樹，酒井敏行
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting VDAC1 and VDAC2.2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，安田周祐，渡邉元樹，酒井敏行
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規スリンダクスルホン結合タンパク質VDACによる細胞周期制御のメカニズムの解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行.
- Organizer
  第18回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-17K19829
[Presentation] 食べて防ごう！がん化学予防への挑戦！2018
- Author(s)
  堀中真野
- Organizer
  おかやまバイオアクティブ研究会第53回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] 食べて防ごう！がん化学予防への挑戦！2018
- Author(s)
  堀中真野
- Organizer
  おかやまバイオアクティブ研究会第53回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19829
[Presentation] FGFR inhibitor BGJ398 and HDAC inhibitor OBP-801 synergistically induce apoptosis in bladder cancer cells.2018
- Author(s)
  堀中真野, 曽和義広, 三木恒治, 浮村理, 酒井敏行.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05260
[Presentation] 食べて防ごう！がん化学予防への挑戦！2018
- Author(s)
  堀中真野.
- Organizer
  おかやまバイオアクティブ研究会第53回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H05260
[Presentation] The novel combination treatment of a HDAC inhibitor OBP-801 with eribulin for triple-negative breast cancer cells.2018
- Author(s)
  小野寿子, 曽和義広, 堀中真野, 飯泉陽介, 渡邉元樹, 田口哲也, 酒井敏行.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05260
[Presentation] FGFR阻害剤BGJ398とHDAC阻害剤OBP-801との併用による、膀胱癌に対する分子標的治療戦略.2018
- Author(s)
  堀中真野, 曽和義広, 酒井敏行.
- Organizer
  第22回日本がん分子標的治療学会学術集会.
- Data Source
  KAKENHI-PROJECT-16H05260
[Presentation] The strategy of molecular-targeting cancer prevention (がんの分子標的予防戦略)2017
- Author(s)
  堀中真野, 飯泉陽介, 渡邉元樹, 増田光治, 曽和義広, 酒井敏行
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] メトホルミンはヒト膵癌細胞に対し、miR-221抑制を介したG1期停止作用と、DR5発現誘導を介したTRAIL感受性増強作用を有する2016
- Author(s)
  堀中真野、田中良一、友杉充宏、曽和義広、酒井敏行
- Organizer
  第15回分子予防環境医学研究会
- Place of Presentation
  栃木
- Year and Date
  2016-01-30
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] メトホルミンはヒト膵癌細胞に対し、miR-221抑制を介したG1期停止作用と、DR5発現誘導を介した TRAIL感受性増強作用を有する2016
- Author(s)
  堀中真野、田中良一、友杉充宏、曽和義広、酒井敏行
- Organizer
  第15回分子予防環境医学研究会
- Place of Presentation
  栃木
- Year and Date
  2016-01-30
- Data Source
  KAKENHI-PROJECT-26670336
[Presentation] 転写因子MZF-1を介したsulindac sulfideによるDR5発現誘導機構2015
- Author(s)
  堀中真野、吉田達士、友杉充宏、曽和義広、酒井敏行
- Organizer
  第14回分子予防環境医学研究会
- Place of Presentation
  大阪
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] sulindac sulfideによるMZF1発現調節を介したTRAIL感受性増強2015
- Author(s)
  堀中真野、吉田達士、曽和義広、酒井敏行
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] がんの分子標的予防戦略2015
- Author(s)
  堀中真野、曽和義広、酒井敏行
- Organizer
  がん予防学術大会2015
- Place of Presentation
  さいたま
- Year and Date
  2015-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] がんの分子標的予防戦略2015
- Author(s)
  堀中真野、曽和義広、酒井敏行
- Organizer
  がん予防学術大会2015
- Place of Presentation
  さいたま
- Year and Date
  2015-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-26670336
[Presentation] microRNA発現調節によるTRAIL発現増強作用の解析2015
- Author(s)
  堀中真野、酒井敏行
- Organizer
  第85回日本衛生学会総会
- Place of Presentation
  和歌山
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells.2015
- Author(s)
  堀中真野、吉田達士、曽和義広、酒井敏行
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] sulindac sulfideによるTRAIL感受性増強作用2014
- Author(s)
  堀中真野、吉田達士、友杉充宏、酒井敏行
- Organizer
  第84回日本衛生学会学術総会
- Place of Presentation
  岡山
- Year and Date
  2014-05-27
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Lactobacilli induce TRAIL production in human PBMC and facilitate natural killer activity against cancer cells.2014
- Author(s)
  Mano Horinaka, Tatsushi Yoshida, Atsuko Kishi, Kaoru Akatani, Takashi Yasuda, Junji Kouhara, Miki Wakada, Toshiyuki Sakai
- Organizer
  The 5th Asian-Pacific Topic Conference
- Place of Presentation
  神戸
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26670336
[Presentation] 癌の「分子標的併用予防法」の開発―イブプロフェンによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強―2014
- Author(s)
  堀中真野,藤堂桃子,友杉充宏,田中良一,井川陽菜,曽和義広,石川秀樹,藤原斉,大辻英吾,酒井敏行
- Organizer
  第13回分子予防環境医学研究会
- Place of Presentation
  和歌山
- Year and Date
  2014-02-01
- Data Source
  KAKENHI-PROJECT-24659304
[Presentation] イブプロフェンによるTRAIL感受性増強作用2014
- Author(s)
  堀中真野、藤堂桃子、友杉充宏、田中良一、井川陽菜、曽和義広、石川秀樹、藤原斉、大辻英吾、酒井敏行
- Organizer
  第21回日本がん予防学会
- Place of Presentation
  東京
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] 癌の「分子標的併用予防法」の開発―イブプロフェンによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強―2014
- Author(s)
  堀中真野, 藤堂桃子, 友杉充宏, 田中良一, 井川陽菜, 曽和義広, 石川秀樹, 藤原斉, 大辻英吾, 酒井敏行
- Organizer
  第13回分子予防環境医学研究会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Lactobacilli induce TRAIL production in human PBMC and facilitate natural killer activity against cancer cells.2014
- Author(s)
  Mano Horinaka, Tatsushi Yoshida, Atsuko Kishi, Kaoru Akatani, Takashi Yasuda, Junji Kouhara, Miki Wakada, Toshiyuki Sakai
- Organizer
  The 5th Asian-Pacific Topic Conference
- Place of Presentation
  神戸
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation. (イブプロフェンによるDR5の発現誘導とTRAIL誘導性アポトーシスの増強)2014
- Author(s)
  藤堂桃子、堀中真野、友杉充宏、石川秀樹、曽和義広、藤原斉、大辻英吾、酒井敏行
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] イブプロフェンによるDR5の発現誘導とTRAIL誘導性アポトーシスの増強2013
- Author(s)
  藤堂桃子,堀中真野,友杉充宏,田中良一,井川陽菜,曽和義広,酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-24659304
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2013
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス(金沢)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] XIAPやsurvivinの発現抑制を介した、メチルグリオキサールのTRAIL感受性増強作用2013
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第20回日本がん予防学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] メチルグリオキサールは癌細胞において XIAP や survivin の発現を減少させ、TRAIL 感受性を増強する2013
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくば
- Year and Date
  2013-01-01
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 癌の分子標的予防の腫瘍免疫への応用.日本衛生学会奨励賞受賞講演.2013
- Author(s)
  堀中真野
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Glyoxalase経路の抑制によるTRAIL感受性の増強2013
- Author(s)
  堀中真野, 谷口浩也, 酒井敏行
- Organizer
  第16回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] Targeting glyoxalase pathway enhances TRAIL efficacy by down-regulating the expression of anti-apoptotic molecules.2013
- Author(s)
  谷口浩也, 堀中真野, 矢野公大, 酒井敏行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24689031
[Presentation] methylglyoxal による XIAP とsurvivin の発現抑制と、TRAIL 誘導性アポトーシスの増強2013
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 癌の分子標的予防の腫瘍免疫への応用. 日本衛生学会奨励賞受賞講演2013
- Author(s)
  堀中真野
- Organizer
  第83回日本衛生学会学術総会.
- Place of Presentation
  金沢
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2012
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 酪酸菌による好中球からのTRAIL放出促進機構とその抗腫瘍効果の検討2012
- Author(s)
  神農雅秀, 堀中真野, 三木恒治, 酒井敏行
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  岡山
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌による好中球からの TRAIL 放出機構の解析とその臨床応用への検討.2012
- Author(s)
  神農雅秀, 堀中真野, 上田崇, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  100回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-04-23
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌によるTRAIL誘導とその抗腫瘍効果の検討-第2報-2012
- Author(s)
  堀中真野, 他
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都大学吉田キャンパス(京都)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 酪酸菌による TRAIL 誘導とその抗腫瘍効果の検討-第2 報-.2012
- Author(s)
  堀中真野, 神農雅秀, 三木恒治, 酒井敏行
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌による好中球からの TRAIL 放出促進機構とその抗腫瘍効果の検討2012
- Author(s)
  神農雅秀, 堀中真野, 三木恒治, 酒井敏行
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  第11回分子予防環境医学研究会
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌によるTRAIL誘導とその抗腫瘍効果の検討-第2報-2012
- Author(s)
  堀中真野, 神農雅秀, 三木恒治, 酒井敏行
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌によるTRAIL誘導とその抗腫瘍効果の検討-第2報-2012
- Author(s)
  堀中真野他
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンによる RB 非依存的な G1 期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] TRAIL-DR5経路を用いた癌の分子標的併用予防法2011
- Author(s)
  堀中真野
- Organizer
  第10回分子予防環境医学研究会
- Place of Presentation
  京都
- Year and Date
  2011-01-21
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌によるTRAIL誘導とその膀胱癌治療への応用に関する検討2011
- Author(s)
  神農雅秀, 堀中真野, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  第99回日本泌尿器科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 食品成分を用いたTRAIL経路活性化による新規癌予防戦略2011
- Author(s)
  堀中真野
- Organizer
  がん予防大会2011京都
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンによるRB非依存的なG1期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏, 他
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 食品成分を用いたTRAIL経路活性化による新規癌予防戦略2011
- Author(s)
  堀中真野
- Organizer
  がん予防大会2011京都
- Place of Presentation
  京都
- Year and Date
  2011-06-21
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] Lactobacillus plantarum induces TRAIL production and facilitates natural killer activity against cancer cells2011
- Author(s)
  Mano Horinaka, Tatsushi Yoshida, Atsuko Kishi, Kaoru Akatani, Takashi Yasuda, Junji Kouhara, Miki Wakada, Toshiyuki Sakai
- Organizer
  AACR 102nd Annual Meeting 2011
- Place of Presentation
  Orlando, FL 32819, USA
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌による好中球からのTRAIL誘導とその抗腫瘍効果の検討2011
- Author(s)
  神農雅秀, 堀中真野, 酒井敏行
- Organizer
  日本がん分子標的治療学会第15回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌による好中球からのTRAIL誘導とその抗腫瘍効果の検討2011
- Author(s)
  神農雅秀, 堀中真野, 三木恒治, 酒井敏行
- Organizer
  第18回日本がん予防学会
- Place of Presentation
  京都
- Year and Date
  2011-06-21
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 食品成分を用いたTRAIL経路活性化による新規癌予防戦略2011
- Author(s)
  堀中真野
- Organizer
  第18回日本がん予防学会
- Place of Presentation
  京都
- Year and Date
  2011-06-21
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] Lactobacillus plantarum induces TRAIL production and facilitates natural killer activity against cancer cells2011
- Author(s)
  Horinaka M., et al
- Organizer
  AACR 102^<nd> Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center (Orlando Florida, U.S.A.)
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] The stimulation of Clostridium butyricum on neutrophilis causes the release of TRAIL.(酪酸菌による好中球からのTRAIL誘導とその抗腫瘍効果の検討.)2011
- Author(s)
  神農雅秀, 堀中真野, 本郷文弥, 高羽夏樹, 河内明宏, 三木恒治, 酒井敏行
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 酪酸菌によるTRAIL誘導とその抗腫瘍効果の検討2011
- Author(s)
  神農雅秀, 堀中真野, 高羽夏樹, 三木恒治, 酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] フラボンによるRB非依存的G1期停止の誘導2011
- Author(s)
  友杉充宏, 他
- Organizer
  がん予防大会2011京都
- Place of Presentation
  京都府立医科大学図書館ホール(京都)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] フラボンによる RB 非依存的 G1 期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  がん予防大会 2011 京都
- Place of Presentation
  京都府立医科大学図書館ホール(京都)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 食品成分を用いたTRAIL経路活性化による新規癌予防戦略2011
- Author(s)
  堀中真野
- Organizer
  がん予防大会2011京都
- Place of Presentation
  京都府立医科大学図書館ホール(京都)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 乳酸菌によるTRAIL発現誘導に着目した癌の分子標的予防2010
- Author(s)
  堀中真野, 他
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cell2010
- Author(s)
  堀中真野, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター(大阪)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 乳酸菌はヒト末梢血リンパ球からTRAIL産生を誘導することで、ヒト癌細胞に対する細胞傷害活性を増強する2010
- Author(s)
  堀中真野, 他
- Organizer
  がん予防学術大会2010札幌
- Place of Presentation
  北海道大学学術交流会館(札幌)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 乳酸菌によるTRAIL発現誘導に着目した癌の分子標的予防2010
- Author(s)
  堀中真野, 他
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cell2010
- Author(s)
  堀中真野, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] 乳酸菌はヒト末梢血リンパ球からTRAIL産生を誘導することで、ヒト癌細胞に対する細胞傷害活性を増強する2010
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会2010札幌
- Place of Presentation
  札幌
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22790547
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2009
- Author(s)
  堀中真野
- Organizer
  第16回がん予防学会
- Place of Presentation
  愛知
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] 植物成分による分子標的癌予防の提案2009
- Author(s)
  堀中真野, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] イソリキリチゲニンはヒト大腸癌細胞に対してTRAIL誘導性アポトーシスを増強する2009
- Author(s)
  堀中真野, 他
- Organizer
  第79回日本衛生学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Combination-oriented molecular-targeting prevention for cancer; combination with TRAIL and DR5 inducer.2009
- Author(s)
  Horinaka M.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Combination-oriented molecular-targeting prevention for cancer ; combination with TRAIL and DR5 inducer2009
- Author(s)
  Horinaka M., et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜(●)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] イソリキリチゲニンはヒト大腸癌細胞に対してTRAIL誘導性アポトーシスを増強する2009
- Author(s)
  堀中真野
- Organizer
  第79回日本衛生学会学術総会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Combination-oriented molecular-targeting prevention for cancer ; combination with TRAIL and DR5 inducer2009
- Author(s)
  Horinaka M., et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] 植物成分による分子標的癌予防の提案2009
- Author(s)
  堀中真野, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] 植物成分による分子標的癌予防の提案2009
- Author(s)
  堀中真野
- Organizer
  第9回分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] 植物成分による分子標的癌予防の提案2009
- Author(s)
  堀中真野, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] イソリキリチゲニンはヒト大腸癌細胞に対してTRAIL誘導性アポトーシスを増強する2009
- Author(s)
  堀中真野, 他
- Organizer
  日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2009
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会
- Place of Presentation
  愛知(名古屋)
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] イソリキリチゲニンはヒト大腸癌細胞に対してTRAIL誘導性アポトーシスを増強する2009
- Author(s)
  堀中真野, 他
- Organizer
  日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2009
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会
- Place of Presentation
  愛知(名古屋)
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] イソリキリチゲニンはヒト大腸癌細胞に対してTRAIL誘導性アポトーシスを増強する2009
- Author(s)
  堀中真野, 他
- Organizer
  日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] NDGAによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強2008
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2008
- Author(s)
  堀中真野, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] NDGAによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強2008
- Author(s)
  堀中真野
- Organizer
  第15回がん予防学会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Lipoxygenase inhibitors induce DR5/TRAIL-R2 expression andsensitize malignant tumor cells to TRAIL-induced apoptosis2008
- Author(s)
  Horinaka M, et al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Lipoxygenase inhibitors induce DR5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis2008
- Author(s)
  Horinaka M, et al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] NDGAによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強2008
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2008
- Author(s)
  堀中真野, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] NDGAによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強2008
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2008
- Author(s)
  堀中真野, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] バイカレインによる癌細胞特異的なDR5遺伝子の発現誘導とTRAIL感受性増強機構の解析2008
- Author(s)
  堀中真野
- Organizer
  第13回日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Lipoxygenase inhibitors induce DR5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.2008
- Author(s)
  Horinaka M.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20890191
[Presentation] Lipoxygenase inhibitors induce DR5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis2008
- Author(s)
  Horinaka M, et.al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] Dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand2007
- Author(s)
  Horinaka M., et. al.
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] アピゲニンは腫瘍細胞のDR5を安定化させ、TRAIL誘導性apoptosisに対する感受性を相乗的に増強する2007
- Author(s)
  堀中真野, 他
- Organizer
  がん予防大会(日本がん予防学会)
- Place of Presentation
  東京
- Year and Date
  2007-07-12
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand.2007
- Author(s)
  Horinaka M., et. al.
- Organizer
  International Conference on Food Factors for Health Promotion
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] カロテノイドHalocynthiaxanthin、PeridininはDR5遺伝子の発現を誘導し、TRAIL誘導性アポトーシスを増強する2007
- Author(s)
  堀中真野, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  北九州
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] 癌の「分子標的併用療法・予防法」の開発-apigeninによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強-2007
- Author(s)
  堀中真野, 他
- Organizer
  がん分子標的治療研究会
- Place of Presentation
  大阪
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] アピゲニンはDR5遺伝子の発現を誘導し、TRAIL誘導性アポトーシスを増強する2007
- Author(s)
  堀中真野, 他
- Organizer
  第77回日本衛生学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand.2007
- Author(s)
  Horinaka M., et. al.
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Los Angeles, CA, U. S. A.
- Year and Date
  2007-04-18
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] 癌の「分子標的併用予防法」の開発-ルテオリンによるDR5遺伝子の発現誘導とTRAIL誘導性アポトーシスの増強-2006
- Author(s)
  堀中真野, 他
- Organizer
  第76回日本衛生学会総会
- Place of Presentation
  山口
- Year and Date
  2006-03-26
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] methylglyoxalによるXIAPとsurvivinの発現抑制と、TRAIL誘導性アポトーシスの増強
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] アクラルビシンはp53非依存的にDR5の発現を誘導し、TRAIL感受性を増強する
- Author(s)
  堀中真野, 吉田達士, 中田晋, 白石匠, 酒井敏行
- Organizer
  日本がん分子標的治療学会第16回学術集会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 酪酸菌による好中球からのTRAIL放出機構の解析とその臨床応用への検討
- Author(s)
  神農雅秀, 堀中真野, 上田崇, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  第100回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659304
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] Aclarubicin enhances TRAIL-induced apoptosis through DR5 up-regulation
- Author(s)
  堀中真野, 吉田達士, 中田晋, 白石匠, 友杉充宏, 三木恒治, 酒井敏行
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] メチルグリオキサールは癌細胞においてXIAPやsurvivinの発現を減少させ、TRAIL感受性を増強する
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] イブプロフェンによるDR5の発現誘導と、TRAIL誘導性アポトーシスの増強
- Author(s)
  藤堂桃子, 堀中真野, 友杉充宏, 曽和義広, 大辻英吾, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 癌の分子標的予防の腫瘍免疫への応用. 日本衛生学会奨励賞受賞講演
- Author(s)
  堀中真野
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Invited
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌による好中球からのTRAIL放出機構の解析とその臨床応用への検討
- Author(s)
  神農雅秀, 堀中真野, 上田崇, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  第100回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 癌の分子標的予防の腫瘍免疫への応用. 日本衛生学会奨励賞受賞講演.
- Author(s)
  堀中真野
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Invited
- Data Source
  KAKENHI-PROJECT-24659304

1. SAKAI Toshiyuki (20186993)

# of Collaborated Projects: 15 results

# of Collaborated Products: 150 results
2. SOWA Yoshihiro (70315935)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
3. 安田周祐 (10643398)

# of Collaborated Projects: 5 results

# of Collaborated Products: 32 results
4. YOGOSAWA Shingo (70381936)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. MASUDA Mitsuharu (10305568)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 飯泉陽介 (20533178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. MATSUZAKI Yoichiro (70282522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIDA Tatsushi (80315936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
9. 友杉充宏 (60533429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. 渡邉元樹 (40723581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 石川秀樹 (30351795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鈴木孝禎 (90372838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中尾俊雅 (30829320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 早川芳弘 (10541956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 森直樹 (30293913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 森哲 (80271005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 木村泰久 (10415143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中崎敦夫 (00366428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 栗山長門 (60405264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 谷口恵香 (70882942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
21. 村田博昭 (90360031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 堀江直行 (70905968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. AONO yuichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. KURODA Junya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. YAMADA Tadaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 大谷隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 内野順治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 高山浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 藤原斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 大辻英吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 菊地利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 阿部貴志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 飯居宏美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 中田晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horinaka Mano 堀中 真野

TOMOSUGI Mano 友杉 真野

堀中真野

HORINAKA Mano 堀中 真野

友杉 真野(堀中真野) トモスギ マノ

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Development of preemptive medical care for pre-symptomatic MEN1 gene mutation carriersPrincipal Investigator

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Basic research for prevention of arteriosclerosis by cancer preventive ingredients with RB activation abilityPrincipal Investigator

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Preventive strategy against arsenic carcinogenesis by TRAIL pathway activation and RB activationPrincipal Investigator

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Study of the COX-independent mechanisms in the efficacy of prevention for colon carcinogenesis by NSAIDsPrincipal Investigator

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Study of the mechanism of cancer-risk increase due to diabetes and suggestion of the molecular-targeting cancer prevention for the cancerPrincipal Investigator

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Horinaka Mano 堀中真野

TOMOSUGI Mano 友杉真野

HORINAKA Mano 堀中真野

友杉真野(堀中真野) トモスギマノ