ito shigemi 伊藤しげみ

… Alternative Names

Ito Shigemi 伊藤しげみ

ITO Shigemi 伊藤しげみ

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Researcher Number	80600006
Affiliation (Current)	2025: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん薬物療法研究部, 特任研究員
Affiliation (based on the past Project Information) *help	2021 – 2022: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん薬物療法研究部, 特任研究員 2011 – 2019: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん薬物療法研究部, 特任研究員
Review Section/Research Field	Principal Investigator Tumor biology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Tumor therapeutics Except Principal Investigator Obstetrics and gynecology / Neurosurgery / Tumor therapeutics / Tumor biology / Cerebral neurosurgery / Clinical oncology
Keywords	Principal Investigator がん / Pkm / 代謝 / 食事療法 / 栄養 / 食事 / ナイアシン / ビタミン / 腫瘍免疫 / 分子標的治療 … More / 小細胞肺がん / Pkm2 / Pkm1 / がん細胞の特性 / グルコース代謝 / NAD代謝 / 肺がん / スプライシング / PKM / ワールブルグ効果 / 解糖系 … More Except Principal Investigator PKM / ワールブルグ効果 / 代謝 / 解糖系 / スプライシング / がん / グリオーマ / 婦人科腫瘍学 / プロテインホスファターゼ / 卵巣がん / 代謝異常 / 分子標的治療 Less

Nutritional approach for activation of tumor immunity: mechanisms and therapeutic applicationsPrincipal Investigator
- Principal Investigator
  
  Ito Shigemi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Tageting the PKM1-NAD metabolic axis in small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Ito Shigemi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Insufficiency of a novel anti-oncogene and mouse ovarian tumorigenesis
- Principal Investigator
  
  YAMADA Hidekazu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Aerobic glucose metabolism and Pkm1 in small cell lung cancer.Principal Investigator
- Principal Investigator
  
  ITO Shigemi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Analysis of human samples for developing a novel therapy that target the Warburg effect
- Principal Investigator
  
  SATO IKURO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Fluorescent live-imaging of the switching of pyruvate kinase isoforms during tumorigenesisPrincipal Investigator
- Principal Investigator
  
  ITO SHIGEMI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Roles for pyruvate kinase M in metabolic rewiring during gliomagenesis
- Principal Investigator
  
  KATAKURA RYUICHI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Roles for pyruvate kinase M in tumorigenesis
- Principal Investigator
  
  TANUMA NOBUHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Development of novel therapy targeting the Warburg effect of cancer
- Principal Investigator
  
  SATO Ikuro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical oncology
- Research Institution
  Miyagi Cancer Center Research Institute
Aberrant pre-mRNA splicing that contributes to increased glycolysis in glioma
- Principal Investigator
  
  KATAKURA Ryuuichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Miyagi Cancer Center Research Institute

All 2022 2020 2019 2018 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] A case of anaplastic pancreatic cancer with osteoclast-like giant cells during follow-up of a branch-duct pancreatic intraductal papillary mucinous tumor2022
- Author(s)
  太田健介、佐藤郁郎、虻江誠、目黒陸、日下順、岩井渉、涌井裕太、及川智之、鈴木眞一、伊藤しげみ
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 119 Issue: 10 Pages: 961-968
- DOI
  10.11405/nisshoshi.119.961
- ISSN
  0446-6586, 1349-7693
- Year and Date
  2022-10-10
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07313, KAKENHI-PROJECT-21K19748
[Journal Article] Novel activating KRAS mutation candidates in lung adenocarcinoma2020
- Author(s)
  Abe Jiro、Tanuma Nobuhiro、Nomura Miyuki、Ito Shin、Kasugai Isao、Sato Ikuro、Tamai Keiichi、Mochizuki Mai、Yamaguchi Kazunori、Shima Hiroshi、Okada Yoshinori、Yasuda Jun
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 3 Pages: 690-696
- DOI
  10.1016/j.bbrc.2019.11.151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-17K07231
[Journal Article] Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer2020
- Author(s)
  Kudo Kei、Nomura Miyuki、Sakamoto Yoshimi、Ito Shigemi、Morita Mami、Kawai Masaaki、Yamashita Yoji、Ito Kiyoshi、Yamada Hidekazu、Shima Hiroshi、Yaegashi Nobuo、Tanuma Nobuhiro
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 9 Pages: 1379-1388
- DOI
  10.1002/1873-3468.13736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09469, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-19K09109, KAKENHI-PROJECT-18K09243, KAKENHI-PROJECT-17K07231, KAKENHI-PROJECT-18K15965
[Journal Article] Risk factors for cervical lymph node metastasis in endoscopically resected superficial hypopharyngeal cancers2019
- Author(s)
  Imai Takayuki、Ito Shigemi、Oikawa Tomoyuki、Asada Yukinori、Matsumoto Ko、Miyazaki Takefumi、Yamazaki Tomoko、Satoh Ikuro、Noguchi Tetsuya、Matsuura Kazuto
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 46 Issue: 3 Pages: 424-430
- DOI
  10.1016/j.anl.2018.09.005
- NAID
  130007895065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11414, KAKENHI-PROJECT-17K07231
[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018
- Author(s)
  M Morita, T Sato, M Nomura, Y Sakamoto, Y Inoue, R Tanaka, S Ito, K Kurosawa, K Yamaguchi, Y Sugiura, H Takizaki, Y Yamashita, R Katakura, I Sato, Y Okada, H Watanabe, G Kondoh, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 12 Issue: 3 Pages: 355-367
- DOI
  10.1016/j.ccell.2018.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K09597, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K16876, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19745, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K07231
[Journal Article] Clear cell carcinoma of the nasal cavity: A case report from histopathological viewpoint.2016
- Author(s)
  Takayuki Imai, Ikuro Satoh, Ko Matsumoto, Shigemi Ito, Yukinori Asada, Kengo Kato, Yasutoshi Koshiba, Shigeru Saijo, Kazuto Matsuura
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 43(1) Issue: 1 Pages: 108-11
- DOI
  10.1016/j.anl.2015.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14387, KAKENHI-PROJECT-15K20238
[Journal Article] Mixed squamous cell and glandular papilloma of the lung resembling early adenocarcinoma: A case report.2016
- Author(s)
  Jiro Abe, Shigemi Ito, Satomi Takahashi, Ikuro Sato, Ryota Tanaka, Taku Sato and Toshimasa Okazaki
- Journal Title
  
  Annals of Medicine and Surgery
  
  Volume: 7 Pages: 61-64
- DOI
  10.1016/j.amsu.2016.03.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14387
[Journal Article] Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA2015
- Author(s)
  Hayashi K, Momoi Y , Tanuma N, Kishimoto A, Ogoh H, Kato H, Suzuki M, Sakamoto Y, Inoue Y, Nomura M, Kiyonari H, Sakayori M, Fukamachi K, Kakugawa Y, Yamashita Y, Ito S, Sato I, Suzuki A, Nishio M, Suganuma M, Watanabe T, and Shima H
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 35 Pages: 4647-55
- DOI
  10.1038/onc.2014.398
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24591928, KAKENHI-PROJECT-25861168, KAKENHI-PROJECT-15K10081, KAKENHI-PROJECT-26430130, KAKENHI-PROJECT-15K19081, KAKENHI-PROJECT-15K20237, KAKENHI-PROJECT-25430163
[Journal Article] Anterior gradient 2 is correlated with EGFR mutation in lung adenocarcinoma tissues.2015
- Author(s)
  Narumi S, Miki Y, Hata S, Ebina M, Saito M, Mori K, Kobayashi M, Suzuki T, Iwabuchi E, Sato I, Maemondo M, Endo C, Inoue A, Kondo T, Yamada-Okabe H, Ichinose M, Sasano H.
- Journal Title
  
  Int J Biol Markers.
  
  Volume: 30(2) Issue: 2 Pages: 234-242
- DOI
  10.5301/jbm.5000131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04711, KAKENHI-PROJECT-25430163
[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes increases susceptibility to ultraviolet-B-induced carcinogenesis.2015
- Author(s)
  Kato H, Kurosawa K, Inoue Y, Tanuma N, Momoi Y, Hayashi K, Ogoh H, Nomura M, Sakayori M, Kakugawa Y, Yamashita Y, Miura K, Maemondo M, Katakura R, Ito S, Sato M, Sato I, Chiba N, Watanabe T, Shima H.
- Journal Title
  
  Cancer Lett.
  
  Volume: 365 Issue: 2 Pages: 223-228
- DOI
  10.1016/j.canlet.2015.05.022
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K10081, KAKENHI-PROJECT-26430130, KAKENHI-PROJECT-26461967, KAKENHI-PROJECT-15K14387, KAKENHI-PROJECT-15K19081, KAKENHI-PROJECT-15K20237, KAKENHI-PROJECT-25430163, KAKENHI-PROJECT-25670609
[Journal Article] Gastric-type endocervical glandular neoplasms associated with aberrant p16 expression and K-RAS gene mutation in Peutz-Jeghers syndrom2014
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 64 Pages: 283-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501326
[Journal Article] Gastric-type endocervical glandular neoplasms associated with aberrant p16 expression and K-RAS gene mutation in Peutz-Jeghers syndrome.2014
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 64 Pages: 283-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640072
[Journal Article] Gastric-type endocervical glandular neoplasms associated with aberrant p16 expression and K-RAS gene mutation in Peutz-Jeghers syndrome.2014
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 64 Pages: 283-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670627
[Journal Article] Gastric-type endocervical glandular neoplasms associated with aberrant p16 expression and K-RAS gene mutation in Peutz-Jeghers syndrom2014
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 64 Pages: 283-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430163
[Journal Article] Case report of Mammary Analog Secretory Carcinoma of the parotid gland.2012
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 62 Pages: 149-52
- NAID
  10031185181
- Data Source
  KAKENHI-PROJECT-23650629
[Journal Article] Case report of Mammary Analog Secretory Carcinoma of the parotid gland.2012
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 62 Pages: 149-52
- NAID
  10031185181
- Data Source
  KAKENHI-PROJECT-24501326
[Journal Article] Case report of Mammary Analog Secretory Carcinoma of the parotid gland.2012
- Author(s)
  Ito S、ほか5名
- Journal Title
  
  Pathol Int.
  
  Volume: 62 Pages: 149-52
- NAID
  10031185181
- Data Source
  KAKENHI-PROJECT-23659700
[Journal Article] Case report of Mammary Analog Secretory Carcinoma of the parotid gland2012
- Author(s)
  Ito S, Ishida E, Skalova A, Matsuura K, Kumamoto H, Sato I
- Journal Title
  
  Pathol Int.
  
  Volume: 62(2) Issue: 2 Pages: 149-52
- DOI
  10.1111/j.1440-1827.2011.02759.x
- NAID
  10031185181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650629, KAKENHI-PROJECT-23659700, KAKENHI-PROJECT-24592613
[Presentation] NAD biogenesis is a targetable vulnerability of small-cell lung and prostate cancers2022
- Author(s)
  大内麻衣、宮原周子、野村美有樹、坂本良美、伊藤しげみ、盛田麻美、佐藤卓、菊池直彦、田沼延公
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K19748
[Presentation] Systemic niacin metabolism that limits efficacy of NAD-targeted therapy in cancer2022
- Author(s)
  野村美有樹、大内麻衣、伊藤しげみ、盛田麻美、菊池直彦、佐藤卓、中川崇、田沼延公
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K19748
[Presentation] 皮膚Ppp6c欠損マウスは、UVB誘導皮膚扁平上皮発がんに高感受性となる2015
- Author(s)
  加藤浩之、田沼延公、三浦康、角川陽一郎、椎葉健一、山下洋二、林克剛、野村美有樹、佐藤郁郎、伊藤しげみ、渡邊利雄、島礼
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K14387
[Presentation] 紫外線誘導皮膚がんにおいて、PP6はがん抑制遺伝子として働く2015
- Author(s)
  黒沢是之、後藤孝浩、田沼延公、加藤浩之、佐藤郁郎、伊藤しげみ、島礼、館正弘
- Organizer
  第24回日本形成外科学会基礎学術集会
- Place of Presentation
  岩手県民会館（岩手県・盛岡市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430163
[Presentation] 皮膚Ppp6c欠損マウスは、UVB誘導皮膚扁平上皮発がんに高感受性となる2015
- Author(s)
  加藤浩之、田沼延公、三浦康、角川陽一郎、椎葉健一、山下洋二、林克剛、野村美有樹、佐藤郁郎、伊藤しげみ、渡邊利雄、島礼
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430163
[Presentation] 紫外線誘導皮膚がんにおいて、PP6はがん抑制遺伝子として働く2015
- Author(s)
  黒沢是之、後藤孝浩、田沼延公、加藤浩之、佐藤郁郎、伊藤しげみ、島礼、館正弘
- Organizer
  第24回日本形成外科学会基礎学術集会
- Place of Presentation
  岩手県民会館（岩手県・盛岡市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K14387
[Presentation] Generation of knock-in mice to dissect isoform-specific roles for each splicing isoform of pyruvate kinase M in vivo2013
- Author(s)
  松本祥子、坂本良美、野村美有樹、田中遼大、盛田麻美、伊藤しげみ、椎葉健一、野村栄樹、片倉隆一、山下洋二、佐藤郁郎、渡邊利雄、島礼、田沼延公
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24501326
[Presentation] Generation of knock-in mice to dissect isoform-specific roles for each splicing isoform of pyruvate kinase M in vivo2013
- Author(s)
  松本祥子、坂本良美、野村美有樹、田中遼大、盛田麻美、伊藤しげみ、椎葉健一、野村栄樹、片倉隆一、山下洋二、佐藤郁郎、渡邊利雄、島礼、田沼延公
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640072
[Presentation] Ptprz gene encoding a transmembrene-type protein phosphatase is up-regulated by Sox-2 in glioma.2013
- Author(s)
  Yoji Yamashita,Nobuhiro Tanuma,Ichiro Shibahara,Yukihiro Sonoda,Masayuki Kanamori,Ryuta Saito,Toshihiro Kumabe,Teiji Tominaga,Hiroshi Shima,Ryuichi Katakura
- Organizer
  AACR ANNUAL MEETING 2013
- Place of Presentation
  Washington,DC
- Data Source
  KAKENHI-PROJECT-25670627
[Presentation] Generation of knock-in mice to dissect isoform-specific roles for each splicing isoform of pyruvate kinase M in vivo2013
- Author(s)
  松本祥子、坂本良美、野村美有樹、田中遼大、盛田麻美、伊藤しげみ、椎葉健一、野村栄樹、片倉隆一、山下洋二、佐藤郁郎、渡邊利雄、島礼、田沼延公
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25430163
[Presentation] Generation of knock-in mice to dissect isoform-specific roles for each splicing isoform of pyruvate kinase M in vivo2013
- Author(s)
  松本祥子、坂本良美、野村美有樹、田中遼大、盛田麻美、伊藤しげみ、椎葉健一、野村栄樹、片倉隆一、山下洋二、佐藤郁郎、渡邊利雄、島礼、田沼延公
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25670627
[Presentation] 炎症性脳アミロイド血管症の一例2012
- Author(s)
  山下洋二、鈴木博義、伊藤しげみ、佐藤郁郎、片倉隆一
- Organizer
  第19回東北脳神経病理研究会
- Place of Presentation
  福島
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23659700
[Presentation] 炎症性脳アミロイド血管症の一例2012
- Author(s)
  山下洋二、鈴木博義、伊藤しげみ、佐藤郁郎、片倉隆一
- Organizer
  第19回東北脳神経病理研究会
- Place of Presentation
  風島
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23650629

1. TANUMA Nobuhiro (40333645)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
2. SATO Ikuro (50225918)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
3. KATAKURA Ryuuichi (10442675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. YAMASHITA Yoji (30420045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. YAMADA Hidekazu (10254012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 島礼 (10196462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SATOU Fumitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 渡辺利雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 今井隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 笹野公伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 前門戸任

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ito shigemi 伊藤 しげみ

Ito Shigemi 伊藤 しげみ

ITO Shigemi 伊藤 しげみ

Research Projects

Research Products

Co-Researchers

Nutritional approach for activation of tumor immunity: mechanisms and therapeutic applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tageting the PKM1-NAD metabolic axis in small cell lung cancerPrincipal Investigator

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Insufficiency of a novel anti-oncogene and mouse ovarian tumorigenesis

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Aerobic glucose metabolism and Pkm1 in small cell lung cancer.Principal Investigator

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Analysis of human samples for developing a novel therapy that target the Warburg effect

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Fluorescent live-imaging of the switching of pyruvate kinase isoforms during tumorigenesisPrincipal Investigator

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Roles for pyruvate kinase M in metabolic rewiring during gliomagenesis

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Roles for pyruvate kinase M in tumorigenesis

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Development of novel therapy targeting the Warburg effect of cancer

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Aberrant pre-mRNA splicing that contributes to increased glycolysis in glioma

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[Journal Article] A case of anaplastic pancreatic cancer with osteoclast-like giant cells during follow-up of a branch-duct pancreatic intraductal papillary mucinous tumor2022

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[Journal Article] Novel activating KRAS mutation candidates in lung adenocarcinoma2020

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[Journal Article] Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer2020

ito shigemi 伊藤しげみ

Ito Shigemi 伊藤しげみ

ITO Shigemi 伊藤しげみ