Awakawa Takayoshi 淡川孝義

… Alternative Names

AWAKAWA Takayoshi 淡川孝義

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Researcher Number	80609834
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2022 – 2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー 2019 – 2022: 東京大学, 大学院薬学系研究科(薬学部), 准教授 2017 – 2018: 東京大学, 大学院薬学系研究科(薬学部), 講師 2015 – 2017: 東京大学, 大学院薬学系研究科(薬学部), 助教 2013 – 2015: 東京大学, 大学院薬学系研究科, 助教 2012 – 2015: 東京大学, 薬学研究科(研究院), 助教 2011: 東京大学, 大学院・薬学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Biomolecular chemistry / Basic Section 38040:Bioorganic chemistry-related / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Transformative Research Areas, Section (II) / Science and Engineering / Transition State Control Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Biomolecular chemistry / Living organism molecular science / Transformative Research Areas, Section (II) / Science and Engineering
Keywords	Principal Investigator 生合成酵素 / 二次代謝酵素 / 生合成工学 / 合成生物学 / 酵素工学 / 酵素機能改変 / 物質生産 / 遷移状態 / テルペン環化 / インドールテルペノイド … More / 生合成 / 創薬シード / 精密機能解析 / 医薬品化合物 / アザインダン / SAM / NAD / 補酵素 / 酵素の精密構造機能解析 / 構造生物学 / 酵素化学 / 予知生合成化学 / 予知生合成科学 / 反応改変 / アルカロイド / 非天然型化合物 / 微生物アルカロイド / 活性アルカロイド / 遺伝子発現系 / 構造解析 / 酵素反応 / 反応解析 / X線結晶構造解析 / テルペンインドールアルカロイド / 酸化酵素 / 酵素精密機能解析 / 酵素立体構造 / エンジニアリング / 飛天年型酵素反応 / テルペンインドール / 非天然型酵素反応 / 酵素構造解析 / テルペン環化酵素 / ゲノムマイニング / 二次代謝 / テルペン / 非天然化合物 / メロテルペノイド / メチル化酵素 / lyngbyatoxin A / プレニル基転移酵素 / teleocidin B / 放線菌 / 異種発現 / 結晶構造解析 / protein kinase C / PKC activator … More Except Principal Investigator 生合成 / 遺伝子 / 合成生物学 / 生合成工学 / 酵素 / 天然物化学 / 反応機構 / 酵素工学 / 物質生産 / 二次代謝酵素 / 機能制御 / 情報科学 / 計算科学 / 有機合成 / 生物合成 / 国際交流 / 天然有機化合物 / 生物活性物質 / 中国南西部 / 生物多様性 / 生合成マシナリー / 天然物生合成 / 創薬資源採集調査 / 構造生物学 / ポリエン化合物 / ポリケタイド合成酵素 / オカダ酸 / 生合成クラスター / 多様性創出 / 遺伝子クラスター / メロテルペノイド Less

生体分子骨格薬用活性化合物の生物合成科学Principal Investigator
- Principal Investigator
  
  淡川孝義
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Institute of Physical and Chemical Research
補酵素NAD由来新規天然物生合成経路由来活性分子の創出Principal Investigator
- Principal Investigator
  
  淡川孝義
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Institute of Physical and Chemical Research
酵素機能発掘と合成生物学による次世代型物質生産系の構築Principal Investigator
- Principal Investigator
  
  淡川孝義
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Institute of Physical and Chemical Research
予知生合成科学・研究総括班
- Principal Investigator
  
  葛山智久
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
医薬品骨格含有新規天然物群の生合成機構解明および改変による薬用活性化合物の創出Principal Investigator
- Principal Investigator
  
  淡川孝義
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Institute of Physical and Chemical Research
  The University of Tokyo
Survey for new drug discovery resources and exploration & elucidation of novel natural product biosynthetic machineries
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Structure-function studies of enzymes involved in natural product biosynthesis for drug discovery
- Principal Investigator
  
  ABE Ikuro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
酵素機能改変による新規活性アルカロイド生産系の構築Principal Investigator
- Principal Investigator
  
  淡川孝義
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
The engineering of terpene cyclase based on the knowledge on control of transition statePrincipal Investigator
- Principal Investigator
  
  Awakawa Takayoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Transition State Control
- Research Institution
  The University of Tokyo
Creation of non-natural enzyme reactions based on three-dimensional structure and expression screeningPrincipal Investigator
- Principal Investigator
  
  Awakawa Takayoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Biosynthetic studies on complex natural products
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Engineering Modular-type Polyketide Synthases
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Functional analyses of teleocidin B biosynthetic enzymesPrincipal Investigator
- Principal Investigator
  
  AWAKAWA Takayoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Biosynthetic Studies on Okadaic Acid
- Principal Investigator
  
  ABE Ikuro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Enzyme engineering for natural product biosynthesis
- Principal Investigator
  
  ABE IKURO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Studies on biosynthetic assembly line of meroterpenoids
- Principal Investigator
  
  ABE IKURO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 微生物を利用した有用物質の製造技術2023
- Author(s)
  淡川孝義
- Total Pages
  7
- Publisher
  シーエムシー出版
- ISBN
  9784781317403
- Data Source
  KAKENHI-PROJECT-23K21363
[Book] 酵素機能発掘と合成生物学による次世代型物質生産系の構築2023
- Author(s)
  淡川孝義
- Total Pages
  6
- Publisher
  アグリバイオ
- Data Source
  KAKENHI-PROJECT-23K21363
[Book] ファルマシア2022
- Author(s)
  淡川　孝義
- Total Pages
  5
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-23K21363
[Book] バイオサイエンスとインダストリー2022
- Author(s)
  淡川孝義
- Total Pages
  3
- Publisher
  (一財)バイオインダストリー協会（JBA）
- Data Source
  KAKENHI-PLANNED-22H05123
[Book] 薬学雑誌2022
- Author(s)
  淡川　孝義
- Total Pages
  7
- Publisher
  公益社団法人日本薬学会
- Data Source
  KAKENHI-PROJECT-23K21363
[Book] 薬学雑誌2022
- Author(s)
  淡川孝義
- Total Pages
  7
- Publisher
  公益社団法人日本薬学会
- Data Source
  KAKENHI-PLANNED-22H05123
[Book] バイオサイエンスとインダストリー2022
- Author(s)
  淡川　孝義
- Total Pages
  3
- Publisher
  (一財)バイオインダストリー協会（JBA）
- Data Source
  KAKENHI-PROJECT-23K21363
[Book] ファルマシア2022
- Author(s)
  淡川　孝義
- Total Pages
  5
- Publisher
  公益社団法人日本薬学会
- Data Source
  KAKENHI-PLANNED-22H05123
[Book] パートナー天然物化学、アルカロイドおよびそのほかの含窒素化合物2021
- Author(s)
  淡川　孝義
- Total Pages
  24
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-17H04763
[Book] パートナー天然物化学、アルカロイドおよびそのほかの含窒素化合物2021
- Author(s)
  淡川孝義
- Total Pages
  24
- Publisher
  南江堂
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Book] Comprehensive Natural Products III: Chemistry and Biology, Chapter18 - Hapalindole-Type Alkaloid Biosynthesis2020
- Author(s)
  Awakawa, T., Liu, X.
- Total Pages
  14
- Publisher
  Elsevier
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Book] Comprehensive Natural Products III: Chemistry and Biology2020
- Author(s)
  Awakawa Takayoshi、Liu Xinyu
- Total Pages
  20
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17KT0095
[Book] Comprehensive Natural Products III: Chemistry and Biology, Chapter18 - Hapalindole-Type Alkaloid Biosynthesis2020
- Author(s)
  Awakawa, T., Liu, X.
- Total Pages
  14
- Publisher
  Elsevier
- ISBN
  9780081026915
- Data Source
  KAKENHI-PROJECT-17H04763
[Book] Comprehensive Natural Products III: Chemistry and Biology2020
- Author(s)
  Awakawa Takayoshi、Liu Xinyu
- Total Pages
  20
- Publisher
  Elsevier
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Book] バイオサイエンスとインダストリー2019
- Author(s)
  荒木康子、淡川孝義、松崎素道、阿部郁朗
- Total Pages
  3
- Publisher
  バイオインダストリー協会
- Data Source
  KAKENHI-PROJECT-17H04763
[Book] Comprehensive Natural Products III: Chemistry and Biology2019
- Author(s)
  Awakawa Takayoshi、Liu Xinyu
- Total Pages
  20
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17H04763
[Book] バイオサイエンスとインダストリー2019
- Author(s)
  荒木康子、淡川孝義、松崎素道、阿部郁朗
- Total Pages
  3
- Publisher
  バイオインダストリー協会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Book] バイオサイエンスとインダストリー2019
- Author(s)
  荒木康子、淡川孝義、松崎素道、阿部郁朗
- Total Pages
  3
- Publisher
  バイオインダストリー協会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Book] テルペンインドールアルカロイドテレオシジンの生合成反応2018
- Author(s)
  淡川　孝義
- Total Pages
  4
- Publisher
  有機合成化学協会誌
- Data Source
  KAKENHI-PROJECT-17H04763
[Book] テルペンインドールアルカロイドテレオシジンの生合成反応2018
- Author(s)
  淡川　孝義
- Total Pages
  4
- Publisher
  有機合成化学協会誌
- Data Source
  KAKENHI-PROJECT-17KT0095
[Book] 微生物由来テルペンインドールアルカロイド-テレオシジン生合2017
- Author(s)
  淡川　孝義、阿部　郁朗
- Total Pages
  15
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17KT0095
[Journal Article] Biosynthesis of enfumafungin-type antibiotic reveals an unusual enzymatic fusion pattern and unprecedented C-C bond cleavage2024
- Author(s)
  Cao, Z.-Q., Wang, G.-Q., Luo, R., Gao, Y.-H., Lv, J.-M., Qin, S.-Y., Chen, G.-D., Awakawa, T., Bao, X.-F., Mei, Q.-H., Yao, X.-S., Hu, D., Abe, I., Gao, H.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 146
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0173
[Journal Article] Structural basis of a pyridoxal 5’-phosphate dependent β-NAD alkylating enzyme2024
- Author(s)
  T. Awakawa,* T. Mori,* L. Barra,* Y. Ahmed, R. Ushimaru, Y. Gao, T. Moriya, N. Adachi, M. Kawasaki, T. Senda, T. Terada, D. Tantillo, I. Abe
- Journal Title
  
  Nature catalysis
  
  Volume: in revision
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Journal Article] Discovery of (±)‐Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase2024
- Author(s)
  Meng Ling-Hong、Awakawa Takayoshi、Li Xiao-Ming、Quan Zhiyang、Yang Sui-Qun、Wang Bin-Gui、Abe Ikuro
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 63 Issue: 26
- DOI
  10.1002/anie.202403963
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Journal Article] Recent developments in the engineered biosynthesis of fungal meroterpenoids2024
- Author(s)
  Zhiyang Quan, Takayoshi Awakawa
- Journal Title
  
  Beilstein J Org Chem
  
  Volume: 20 Pages: 578-588
- DOI
  10.3762/bjoc.20.50
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21363
[Journal Article] Discovery of (±)-penindolenes reveals an unusual indole ring cleavage pathway catalyzed by P450 monooxygenase2024
- Author(s)
  Meng, L.-H.,# Awakawa, T.,# Li, X.-M., Quan, Z., Yang, S.-Q., Wang, B.-G., Abe, I.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 63
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0173
[Journal Article] Unusual cysteine modifications in natural product biosynthesis2024
- Author(s)
  Gao Yaojie、Zhu Yuhao、Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 5 Issue: 4 Pages: 299-311
- DOI
  10.1039/d4cb00020j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-23K21363
[Journal Article] Characterization of Aziridine-Forming α-Ketoglutarate-Dependent Oxygenase in L-Isovaline Biosynthesis2024
- Author(s)
  Zhou Lu、Awakawa Takayoshi、Ushimaru Richiro、Kanaida Masahiro、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 26 Issue: 3 Pages: 724-727
- DOI
  10.1021/acs.orglett.3c04185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-23K21363
[Journal Article] Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams2023
- Author(s)
  Shin Yern-Hyerk、Im Ji Hyeon、Kang Ilnam、Kim Eunji、Jang Sung Chul、Cho Eunji、Shin Daniel、Hwang Sunghoon、Du Young Eun、Huynh Thanh-Hau、Ko Keebeom、Ko Yoon-Joo、Nam Sang-Jip、Awakawa Takayoshi、Lee Jeeyeon、Hong Suckchang、Abe Ikuro、Moore Bradley S.、Fenical William、Yoon Yeo Joon、Cho Jang-Cheon、Oh Dong-Chan
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 145 Issue: 3 Pages: 1886-1896
- DOI
  10.1021/jacs.2c11527
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K21363, KAKENHI-PROJECT-20KK0173
[Journal Article] Catalytic Mechanism of Nonglycosidic C-N Bond Formation by the Pseudoglycosyltransferase Enzyme VldE2023
- Author(s)
  Tsunoda Takeshi、Abuelizz Hatem A.、Samadi Arash、Wong Chin Piow、Awakawa Takayoshi、Brumsted Corey J.、Abe Ikuro、Mahmud Taifo
- Journal Title
  
  ACS Catalysis
  
  Volume: 13 Issue: 20 Pages: 13369-13382
- DOI
  10.1021/acscatal.3c02404
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K21363
[Journal Article] Orthoester formation in fungal meroterpenoid austalide F biosynthesis2023
- Author(s)
  Awakawa Takayoshi、Liu Wei、Bai Tongxuan、Taniguchi Tomo、Abe Ikuro
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 378 Issue: 1871 Pages: 1-6
- DOI
  10.1098/rstb.2022.0037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Structure-based engineering of α-ketoglutarate dependent oxygenases in fungal meroterpenoid biosynthesis2023
- Author(s)
  Awakawa Takayoshi、Mori Takahiro、Ushimaru Richiro、Abe Ikuro
- Journal Title
  
  Natural Product Reports
  
  Volume: 40 Issue: 1 Pages: 46-61
- DOI
  10.1039/d2np00014h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-21K14744, KAKENHI-PROJECT-23K21363, KAKENHI-PROJECT-23K13847, KAKENHI-PROJECT-20KK0173
[Journal Article] Cordycicadins A?D, Antifeedant Polyketides from the Entomopathogenic Fungus Cordyceps cicadae JXCH12022
- Author(s)
 Li Xinyang、Chen He-Ping、Zhou Lin、Fan Jing、Awakawa Takayoshi、Mori Takahiro、Ushimaru Richiro、Abe Ikuro、Liu Ji-Kai
- Journal Title
 
 Organic Letters
 
 Volume: 24 Issue: 47 Pages: 8627-8632
- DOI
 10.1021/acs.orglett.2c03432
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Stereoselectivity and Substrate Specificity of the Fe(II)/α-Ketoglutarate-Dependent Oxygenase TqaL2022
- Author(s)
  Tao Hui、Ushimaru Richiro、Awakawa Takayoshi、Mori Takahiro、Uchiyama Masanobu、Abe Ikuro
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 47 Pages: 21512-21520
- DOI
  10.1021/jacs.2c08116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-22H05123, KAKENHI-PLANNED-22H05125, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-22H00320, KAKENHI-PROJECT-21K14744, KAKENHI-PROJECT-23K21363
[Journal Article] A Multifunctional Cytochrome P450 and a Meroterpenoid Cyclase in the Biosynthesis of Fungal Meroterpenoid Atlantinone B2022
- Author(s)
  Qi Bo-wen、Li Na、Zhang Bei-bei、Zhang Ze-kun、Wang Wen-jing、Liu Xiao、Wang Juan、Awakawa Takayoshi、Tu Peng-fei、Abe Ikuro、Shi She-po、Li Jun
- Journal Title
  
  Organic Letters
  
  Volume: 24 Issue: 13 Pages: 2526-2530
- DOI
  10.1021/acs.orglett.2c00684
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-23K21363
[Journal Article] Biosynthesis of dihydroxyardeemin by heterologous expression2022
- Author(s)
  Zhou Lu、Abe Ikuro、Awakawa Takayoshi
- Journal Title
  
  Tetrahedron
  
  Volume: 127 Pages: 133095-133095
- DOI
  10.1016/j.tet.2022.133095
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Noncanonical Functions of Enzyme Cofactors as Building Blocks in Natural Product Biosynthesis2022
- Author(s)
  Barra Lena、Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  JACS Au
  
  Volume: 2 Issue: 9 Pages: 1950-1963
- DOI
  10.1021/jacsau.2c00391
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-22H05123, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Aziridine Formation by a Fe II /α‐Ketoglutarate Dependent Oxygenase and 2‐Aminoisobutyrate Biosynthesis in Fungi2021
- Author(s)
 Bunno Reito、Awakawa Takayoshi、Mori Takahiro、Abe Ikuro
- Journal Title
 
 Angewandte Chemie International Edition
 
 Volume: 60 Issue: 29 Pages: 15827-15831
- DOI
 10.1002/anie.202104644
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19K15703, KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Reconstitution of Polyketide-Derived Meroterpenoid Biosynthetic Pathway in Aspergillus oryzae2021
- Author(s)
  Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Journal of Fungi
  
  Volume: 7 Issue: 6 Pages: 486-486
- DOI
  10.3390/jof7060486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes2021
- Author(s)
  Mori Takahiro、Kumano Takuto、He Haibing、Watanabe Satomi、Senda Miki、Moriya Toshio、Adachi Naruhiko、Hori Sanae、Terashita Yuzu、Kawasaki Masato、Hashimoto Yoshiteru、Awakawa Takayoshi、Senda Toshiya、Abe Ikuro、Kobayashi Michihiko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6294-6294
- DOI
  10.1038/s41467-021-26585-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03197, KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H00490, KAKENHI-ORGANIZER-19H05679, KAKENHI-PROJECT-23K21363
[Journal Article] Engineered Biosynthesis of Pharmaceutically Important Compounds2021
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: in press
- NAID
  130008032778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04763
[Journal Article] Novel cyclohexyl meroterpenes produced by combinatorial biosynthesis.2021
- Author(s)
  Jiang, J., Li, X., Mori, T., Awakawa, T., Abe, I.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: in press
- NAID
  130008032774
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Journal Article] β-NAD as a building block in natural product biosynthesis2021
- Author(s)
  Barra Lena、Awakawa Takayoshi、Shirai Kohei、Hu Zhijuan、Bashiri Ghader、Abe Ikuro
- Journal Title
  
  Nature
  
  Volume: 600 Issue: 7890 Pages: 754-758
- DOI
  10.1038/s41586-021-04214-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Engineered Biosynthesis of Pharmaceutically Important Compounds2021
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: -
- NAID
  130008032778
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Journal Article] Biosynthesis of sulfonamide and sulfamate antibiotics in Actinomycete2021
- Author(s)
  Awakawa Takayoshi、Barra Lena、Abe Ikuro
- Journal Title
  
  Journal of Industrial Microbiology and Biotechnology
  
  Volume: 48 Issue: 3-4 Pages: 001-001
- DOI
  10.1093/jimb/kuab001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-20H00490
[Journal Article] Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis2021
- Author(s)
  Jiang Jinyan、Li Xinyang、Mori Takahiro、Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 5 Pages: 444-446
- DOI
  10.1248/cpb.c21-00123
- NAID
  130008032774
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-05-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Journal Article] Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis2021
- Author(s)
  Li Xinyang、Awakawa Takayoshi、Mori Takahiro、Ling Meiqi、Hu Dan、Wu Bin、Abe Ikuro
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Issue: 50 Pages: 21425-21432
- DOI
  10.1021/jacs.1c11548
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15703, KAKENHI-PROJECT-21K18246, KAKENHI-PROJECT-20KK0173, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Novel cyclohexyl meroterpenes produced by combinatorial biosynthesis.2021
- Author(s)
  Jiang, J., Li, X., Mori, T., Awakawa, T., Abe, I.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: -
- NAID
  130008032774
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Journal Article] Engineered Biosynthesis of Pharmaceutically Important Compounds2021
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 5 Pages: 415-420
- DOI
  10.1248/cpb.c21-00032
- NAID
  130008032778
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21363
[Journal Article] Enzymatic reactions in teleocidin B biosynthesis2021
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: - Issue: 3 Pages: 467-474
- DOI
  10.1007/s11418-021-01504-2
- NAID
  40022591494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-23K21363
[Journal Article] Biosynthesis of biscognienyne B involving an unprecedented cytochrome P450‐dependent alkynylation2020
- Author(s)
  Abe Ikuro、Lv Jian-Ming、Gao Yao-Hui、Zhao Huan、Awakawa Takayoshi、Liu Ling、Chen Guo-Dong、Yao Xin-Sheng、Hu Dan、Gao Hao
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Issue: 32 Pages: 13531-13536
- DOI
  10.1002/anie.202004364
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-20KK0173, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-20H00490
[Journal Article] Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products2020
- Author(s)
  Kudo Yuta、Awakawa Takayoshi、Du Yi-Ling、Jordan Peter A.、Creamer Kaitlin E.、Jensen Paul R.、Linington Roger G.、Ryan Katherine S.、Moore Bradley S.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 15 Issue: 12 Pages: 3253-3261
- DOI
  10.1021/acschembio.0c00824
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15405, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763
[Journal Article] Extensive expanding the chemical diversity of fusidane-type antibiotics using a stochastic combinational strategy2020
- Author(s)
  Song Xiaojun、Lv Jianming、Cao Zhiqin、Huang Huiyun、Chen Guodong、Awakawa Takayoshi、Hu Dan、Gao Hao、Abe Ikuro、Yao Xinsheng
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 10 Issue: 6 Pages: 1676-1685
- DOI
  10.1016/j.apsb.2020.12.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0173, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-20H00490, KAKENHI-PROJECT-23K21363
[Journal Article] Exploitation and application of unique actinomycetical alkaloid biosynthetic enzymes2019
- Author(s)
  Takayoshi Awakawa
- Journal Title
  
  Actinomycetologica
  
  Volume: 33
- Data Source
  KAKENHI-PROJECT-17KT0095
[Journal Article] Multidomain P450 Epoxidase and a Terpene Cyclase from the Ascochlorin Biosynthetic Pathway in Fusarium sp.2019
- Author(s)
  Quan Zhiyang、Awakawa Takayoshi、Wang Dongmei、Hu Yue、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 7 Pages: 2330-2334
- DOI
  10.1021/acs.orglett.9b00616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-17H04763, KAKENHI-PLANNED-16H06443
[Journal Article] Aminoacyl sulfonamide assembly in SB-203208 biosynthesis2019
- Author(s)
  Hu Zhijuan、Awakawa Takayoshi、Ma Zhongjun、Abe Ikuro
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 184-184
- DOI
  10.1038/s41467-018-08093-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-18K19139
[Journal Article] Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis2019
- Author(s)
  He Fei、Mori Takahiro、Morita Iori、Nakamura Hitomi、Alblova Miroslava、Hoshino Shotaro、Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 12 Pages: 1206-1213
- DOI
  10.1038/s41589-019-0380-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095
[Journal Article] Beijinchromes A–D, Novel Aromatic Compounds Isolated from Nocardia beijingensis NBRC 163422019
- Author(s)
 Hoshino Shotaro、Awakawa Takayoshi、Zhang Huiping、Hayashi Fumiaki、Abe Ikuro
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 67 Issue: 8 Pages: 775-777
- DOI
 10.1248/cpb.c19-00364
- NAID
 130007686331
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2019-08-01
- Language
 English
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-18K05345, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-18K19139
[Journal Article] Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum2019
- Author(s)
  Araki Yasuko、Awakawa Takayoshi、Matsuzaki Motomichi、Cho Rihe、Matsuda Yudai、Hoshino Shotaro、Shinohara Yasutomo、Yamamoto Masaichi、Kido Yasutoshi、Inaoka Daniel Ken、Nagamune Kisaburo、Ito Kotaro、Abe Ikuro、Kita Kiyoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 未定 Issue: 17 Pages: 8269-8274
- DOI
  10.1073/pnas.1819254116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15679, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-18KK0454, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-19H03436, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095
[Journal Article] Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis2019
- Author(s)
  Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Beilstein Journal of Organic Chemistry
  
  Volume: 15 Pages: 1545-1551
- DOI
  10.3762/bjoc.15.157
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095
[Journal Article] Structural Elucidation of Tenebrathin: Cytotoxic C-5-Substituted γ-Pyrone with a Nitroaryl Side Chain from Streptoalloteichus tenebrarius2019
- Author(s)
  Hoshino Shotaro、Mitsuhashi Takaaki、Kikuchi Takashi、Wong Chin Piow、Morita Hiroyuki、Awakawa Takayoshi、Fujita Makoto、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 16 Pages: 6519-6522
- DOI
  10.1021/acs.orglett.9b02443
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-19H04641, KAKENHI-PUBLICLY-19H04649, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17J09712, KAKENHI-PROJECT-17KT0095
[Journal Article] Exploitation and application of unique actinomycetical alkaloid biosynthetic enzymes2019
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Actinomycetologica
  
  Volume: 33
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Journal Article] Exploitation and application of unique actinomycetical alkaloid biosynthetic enzymes2019
- Author(s)
  Awakawa Takayoshi
- Journal Title
  
  Actinomycetologica
  
  Volume: 33
- Data Source
  KAKENHI-PROJECT-17H04763
[Journal Article] Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length Factors in the Biosynthesis of Fogacin Polyketides in Actinoplanes missouriensis2019
- Author(s)
  Sato Kei、Katsuyama Yohei、Yokota Kousuke、Awakawa Takayoshi、Tezuka Takeaki、Ohnishi Yasuo
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 8 Pages: 1039-1050
- DOI
  10.1002/cbic.201800640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-18H02144, KAKENHI-PROJECT-17H04763
[Journal Article] Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis2018
- Author(s)
  Nakashima Yu、Mori Takahiro、Nakamura Hitomi、Awakawa Takayoshi、Hoshino Shotaro、Senda Miki、Senda Toshiya、Abe Ikuro
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41467-017-02371-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-15J12340, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-17H06264
[Journal Article] Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage2018
- Author(s)
  2.Wang, G.-Q., Chen, G.-D., Qin, S.-Y., Hu, D., Awakawa, T., Li, S.-Y., Lv, J.-M., Wang, C.-X., Yao, X.-S., Abe, I., Gao, H.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1838-1838
- DOI
  10.1038/s41467-018-04298-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-17H04763
[Journal Article] Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution2018
- Author(s)
  Awakawa Takayoshi、Fujioka Takuma、Zhang Lihan、Hoshino Shotaro、Hu Zhijuan、Hashimoto Junko、Kozone Ikuko、Ikeda Haruo、Shin-Ya Kazuo、Liu Wen、Abe Ikuro
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3534-3534
- DOI
  10.1038/s41467-018-05877-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-16J01117
[Journal Article] Catenulobactins A and B, Heterocyclic Peptides from Culturing Catenuloplanes sp. with a Mycolic Acid-Containing Bacterium2018
- Author(s)
  Hoshino Shotaro、Ozeki Masahiro、Awakawa Takayoshi、Morita Hiroyuki、Onaka Hiroyasu、Abe Ikuro
- Journal Title
  
  Journal of Natural Products
  
  Volume: 81 Issue: 9 Pages: 2106-2110
- DOI
  10.1021/acs.jnatprod.8b00261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PUBLICLY-17H05435, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-16J01117
[Journal Article] Mirilactams C–E, Novel Polycyclic Macrolactams Isolated from Combined-Culture of Actinosynnema mirum NBRC 14064 and Mycolic Acid-Containing Bacterium2018
- Author(s)
 Hoshino Shotaro、Ozeki Masahiro、Wong Chin Piow、Zhang Huiping、Hayashi Fumiaki、Awakawa Takayoshi、Morita Hiroyuki、Onaka Hiroyasu、Abe Ikuro
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 66 Issue: 6 Pages: 660-667
- DOI
 10.1248/cpb.c18-00143
- NAID
 130007382327
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2018-06-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-18K05345, KAKENHI-PUBLICLY-17H05435, KAKENHI-PROJECT-17H04763
[Journal Article] Umezawamides, new bioactive polycyclic tetramate macrolactams isolated from a combined-culture of Umezawaea sp. and mycolic acid-containing bacterium2018
- Author(s)
  Hoshino Shotaro、Wong Chin Piow、Ozeki Masahiro、Zhang Huiping、Hayashi Fumiaki、Awakawa Takayoshi、Asamizu Shumpei、Onaka Hiroyasu、Abe Ikuro
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 71 Issue: 7 Pages: 653-657
- DOI
  10.1038/s41429-018-0040-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26303005, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-16K18673, KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-18K05345, KAKENHI-PROJECT-18K05385, KAKENHI-PROJECT-17H04763
[Journal Article] Crystalline Sponge Method Enabled the Investigation of a Prenyltransferase-terpene Synthase Chimeric Enzyme, Whose Product Exhibits Broadened NMR Signals2018
- Author(s)
  Mitsuhashi Takaaki、Kikuchi Takashi、Hoshino Shotaro、Ozeki Masahiro、Awakawa Takayoshi、Shi She-Po、Fujita Makoto、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 18 Pages: 5606-5609
- DOI
  10.1021/acs.orglett.8b02284
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-17J09712
[Journal Article] Elucidation and Heterologous Reconstitution of Chrodrimanin B Biosynthesis2018
- Author(s)
  Bai Tongxuan、Quan Zhiyang、Zhai Rui、Awakawa Takayoshi、Matsuda Yudai、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 23 Pages: 7504-7508
- DOI
  10.1021/acs.orglett.8b03268
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-17H04763
[Journal Article] Molecular insights into the Mg2+-dependent allosteric control of indole prenylation by aromatic prenyltransferase AmbP12018
- Author(s)
  Abe Ikuro、Awakawa Takayoshi、Mori Takahiro、Nakashima Yu、Zhai Rui、Wong Chin Piow、Hillwig Matthew、Liu Xinyu
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 印刷中 Issue: 23 Pages: 6810-6813
- DOI
  10.1002/anie.201800855
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-15J12340, KAKENHI-PROJECT-16F16410
[Journal Article] Total Enzyme Syntheses of Napyradiomycins A1 and B12018
- Author(s)
  McKinnie Shaun M. K.、Miles Zachary D.、Jordan Peter A.、Awakawa Takayoshi、Pepper Henry P.、Murray Lauren A. M.、George Jonathan H.、Moore Bradley S.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 51 Pages: 17840-17845
- DOI
  10.1021/jacs.8b10134
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-17H04763
[Journal Article] Biosynthesis of the teleocidin-type terpenoid indole alkaloids2018
- Author(s)
  Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 16 Issue: 26 Pages: 4746-4752
- DOI
  10.1039/c8ob00803e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-17H04763
[Journal Article] Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis2017
- Author(s)
  Lv Jian-Ming、Hu Dan、Gao Hao、Kushiro Tetsuo、Awakawa Takayoshi、Chen Guo-Dong、Wang Chuan-Xi、Abe Ikuro、Yao Xin-Sheng
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1644-1644
- DOI
  10.1038/s41467-017-01813-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836
[Journal Article] Combinatorial Biosynthesis of (+)-Daurichromenic Acid and Its Halogenated Analogue2017
- Author(s)
  Okada Masahiro、Saito Kai、Wong Chin Piow、Li Chang、Wang Dongmei、Iijima Miu、Taura Futoshi、Kurosaki Fumiya、Awakawa Takayoshi、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 12 Pages: 3183-3186
- DOI
  10.1021/acs.orglett.7b01288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-17H05429, KAKENHI-PUBLICLY-17H05436, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-17J10178, KAKENHI-PROJECT-15K07990, KAKENHI-PROJECT-15K07994
[Journal Article] Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides2017
- Author(s)
  Zhang, L., Hashimoto, T., Qin, B., Hashimoto, J., Kozone, I., Kawahara, T., Okada, M., Awakawa, T., Ito, T., Asakawa, Y., Ueki, M., Takahashi, S., Osada, H., Wakimoto, T., Ikeda, H., Shin-ya, K., Abe, I.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 56 Issue: 7 Pages: 1740-1745
- DOI
  10.1002/anie.201611371
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PLANNED-16H06447, KAKENHI-PLANNED-16H06448, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-15H03112, KAKENHI-PROJECT-24688011, KAKENHI-PROJECT-15K12740, KAKENHI-PROJECT-25660085, KAKENHI-PROJECT-16K13084, KAKENHI-PROJECT-16H04905, KAKENHI-PROJECT-17F17114
[Journal Article] Mycolic Acid Containing Bacterium Stimulates Tandem Cyclization of Polyene Macrolactam in a Lake Sediment Derived Rare Actinomycete2017
- Author(s)
  Hoshino Shotaro、Okada Masahiro、Awakawa Takayoshi、Asamizu Shumpei、Onaka Hiroyasu、Abe Ikuro
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 18 Pages: 4992-4995
- DOI
  10.1021/acs.orglett.7b02508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PUBLICLY-17H05429, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-16K18673
[Journal Article] Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP32017
- Author(s)
  Wong Chin Piow、Awakawa Takayoshi、Nakashima Yu、Mori Takahiro、Zhu Qin、Liu Xinyu、Abe Ikuro
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 2 Pages: 560-563
- DOI
  10.1002/anie.201710682
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-15J12340, KAKENHI-PROJECT-16F16410
[Journal Article] Structural insight into the enzymatic formation of bacterial stilbene2016
- Author(s)
  Mori, T., Awakawa, T., Shimomura, K., Saito, Y., Yang, D., Morita, H., Abe, I.
- Journal Title
  
  Cell Chem. Biol.
  
  Volume: 23 Issue: 12 Pages: 1468-1479
- DOI
  10.1016/j.chembiol.2016.10.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-26282210
[Journal Article] Unusual chemistries in fungal meroterpenoid biosynthesis2016
- Author(s)
  Matsuda, Y., Awakawa, T., Mori, T., Abe, I.
- Journal Title
  
  Curr. Opin. Chem. Biol.
  
  Volume: 31 Pages: 1-7
- DOI
  10.1016/j.cbpa.2015.11.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836
[Journal Article] Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases2016
- Author(s)
  T. Mori, L. Zhang, T. Awakawa, S. Hoshino, M. Okada, H. Morita, I. Abe
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 10849-10851
- DOI
  10.1038/ncomms10849
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-26560435, KAKENHI-PROJECT-26282210, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-24688011
[Journal Article] Discovery of key dioxygenases that diverged the paraherquonin and acetoxydehydroaustin pathways in Penicillium brasilianum2016
- Author(s)
  Matsuda, Y., Iwabuchi,T., Fujimoto, T., Awakawa,T., Nakashima, Y., Mori, T., Zhang, H., Hayashi, F., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 38 Pages: 12671-12677
- DOI
  10.1021/jacs.6b08424
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-15J12340
[Journal Article] Rational control of polyketide extender units by structure-based engineering of a crotonyl-CoA carboxylase/ reductase in antimycin biosynthesis2015
- Author(s)
  Zhang, L., Mori, T., Zheng, Q., Awakawa, T., Yan, Y., Liu, W., Abe, I.,
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 54 Issue: 45 Pages: 13462-13465
- DOI
  10.1002/anie.201506899
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J12365, KAKENHI-PROJECT-26560428, KAKENHI-PROJECT-15H01836
[Journal Article] Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase2015
- Author(s)
  Matsuda, Y., Iwabuchi, T., Wakimoto, T., Awakawa, T., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Issue: 9 Pages: 3393-3401
- DOI
  10.1021/jacs.5b00570
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-26560428, KAKENHI-PROJECT-15K12740, KAKENHI-PROJECT-15H03112, KAKENHI-PROJECT-15H01836
[Journal Article] Three acyltetronic acid derivatives: noncanonical cryptic polyketides from Aspergillus niger identified by genome mining2014
- Author(s)
  Yang, X.-L., Awakawa, T., Wakimoto, T., Abe, I.
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 11 Pages: 1578-1583
- DOI
  10.1002/cbic.201402172
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399
[Journal Article] A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis2014
- Author(s)
  Awakawa, T., Zhang, L., Wakimoto, T., Hoshino, S., Mori, T., Ito, T., Ishikawa, J., Tanner, M. E., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 28 Pages: 9910-9913
- DOI
  10.1021/ja505224r
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PLANNED-22108010, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399, KAKENHI-PROJECT-25750382, KAKENHI-PROJECT-26460140
[Journal Article] Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont2014
- Author(s)
  Wakimoto, T., Egami, Y., Nakashima, Y., Wakimoto,Y., Mori, T., Awakawa,T., Ito, T., Kenmoku, H., Asakawa, Y., Piel, J., Abe, I.
- Journal Title
  
  Nature Chem. Biol.
  
  Volume: 10 Issue: 8 Pages: 648-655
- DOI
  10.1038/nchembio.1573
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25303010, KAKENHI-PROJECT-25560399, KAKENHI-PROJECT-26303005, KAKENHI-PROJECT-26460140, KAKENHI-PROJECT-26560428
[Journal Article] Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid2014
- Author(s)
  Matsuda, Y., Wakimoto, T., Mori, T., Awakawa, T., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 43 Pages: 15326-15336
- DOI
  10.1021/ja508127q
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399, KAKENHI-PROJECT-26560428
[Journal Article] Spiro-ring formation is catalyzed by a multifunctional dioxygenase in austinol biosynthesis2013
- Author(s)
  Y. Matsuda, T. Awakawa, T. Wakimoto, and I. Abe
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 30 Pages: 10962-10965
- DOI
  10.1021/ja405518u
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399
[Journal Article] Reconstituted biosynthesis of fungal meroterpenoid andrastin A2013
- Author(s)
  Matsuda, Y., Awakawa, T., Abe, I.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 38 Pages: 8199-8204
- DOI
  10.1016/j.tet.2013.07.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068
[Journal Article] Multiplexing of combinatorial chemistry in antimycin biosynthesis expands the molecular diversity and utility2013
- Author(s)
  Yan Y., Chen, J., Zhang, L., Zheng, Q., Han, Y., Zhang, H., Awakawa, T., Abe, I., Liu, W.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 47 Pages: 12308-12312
- DOI
  10.1002/anie.201305569
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-24651239
[Journal Article] Pyranonigrin E : a novel PKS-NRPS hybrid metabolite from Aspergillus niger ide ntified by genome mining2013
- Author(s)
  Takayoshi Awakawa., Xiao-Long Xia o-Long Yang, Toshiyuki Wakimoto., Ikuro Abe
- Journal Title
  
  Chembiochem
  
  Volume: 14 Issue: 16 Pages: 2095-2099
- DOI
  10.1002/cbic.201300430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02032, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399
[Journal Article] A heptaketide naphthaldehyde produced by a polyketide synthase from Nectria haematococca2012
- Author(s)
  Awakawa, T.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Issue: 13 Pages: 4338-4340
- DOI
  10.1016/j.bmcl.2012.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241068
[Presentation] 酵素機能発掘と合成生物学による次世代型物質生産系の構築2024
- Author(s)
  淡川孝義
- Organizer
  予知生合成科学第三回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Structure functional analysis of PLP enzyme catalyzing (3+2)-annulation reaction between beta-NAD and SAM2023
- Author(s)
  Takayoshi Awakawa, Takahiro Mori, Lena Barra, Kohei Shirai, Ikuro Abe
- Organizer
  4th International Conference on Natural Product Discovery and Development
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 補酵素NADを基質とする天然医薬品化合物生合成機構の解明2023
- Author(s)
  淡川孝義
- Organizer
  日本農芸化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 酵素機能発掘と合成生物学による次世代型物質生産系の構築2023
- Author(s)
  淡川孝義
- Organizer
  予知生合成科学第一回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 補酵素NADを基質とする天然医薬品化合物生合成機構の解明2023
- Author(s)
  淡川孝義
- Organizer
  日本農芸化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 補酵素NADを基質とする天然医薬品化合物生合成機構の解明2023
- Author(s)
  淡川孝義
- Organizer
  天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 補酵素NAD由来天然物生合成経路の利用による新規活性分子の創出2023
- Author(s)
  淡川孝義
- Organizer
  日本薬学会若手東北部会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Novel ADP-Ribose Transfer in NAD-Derived Secondary Metabolite Biosynthesis2023
- Author(s)
  Kohei Shirai、Takayoshi Awakawa、Takahiro Mori、Ikuro Abe
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 薬剤排出トランスポーター阻害剤ardeemin化合物異種生産系の確立2023
- Author(s)
  周律、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Novel ADP-Ribose Transfer in NAD-Derived Secondary Metabolite Biosynthesis2023
- Author(s)
  Kohei Shirai、Takayoshi Awakawa、Takahiro Mori、Ikuro Abe
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 酵素機能発掘と合成生物学による次世代型物質生産系の構築2023
- Author(s)
  淡川孝義
- Organizer
  予知生合成科学第一回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 薬剤排出トランスポーター阻害剤ardeemin化合物異種生産系の確立2023
- Author(s)
  周律、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] β-NAD as a building block in natural product biosynthesis2023
- Author(s)
  Takayoshi Awakawa
- Organizer
  Asian Symposium on Medicinal Plants, Spices and Other Natural Products 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 補酵素NADを基質とする天然医薬品化合物の生合成機構の解明2023
- Author(s)
  淡川孝義, 森貴裕、牛丸理一郎、阿部郁朗
- Organizer
  日本生薬学会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Structure and functional analyses of unique α-ketoglutarate dependent oxygenases in natural product biosynthesis2023
- Author(s)
  Takayoshi Awakawa, Takahiro Mori, Richiro Ushimaru, Ikuro Abe
- Organizer
  予知生合成科学日独生合成セミナー
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Structure functional analysis of PLP enzyme catalyzing (3+2)-annulation reaction between beta-NAD and SAM2023
- Author(s)
  Takayoshi Awakawa, Takahiro Mori, Lena Barra, Kohei Shirai, Ikuro Abe
- Organizer
  4th International Conference on Natural Product Discovery and Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] beta-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川孝義
- Organizer
  The 1st Japan/China Joint Young Researcher Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] beta-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川孝義
- Organizer
  Sapporo Summer Seminar on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Tailoring reactions of azaindane dinucleotide in NAD-derived secondary metabolite biosynthesis2022
- Author(s)
  Kohei Shirai, Takayoshi Awakawa, Lena Barra, Ikuro Abe
- Organizer
  NWO-JSPS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 補酵素NADを基質とする天然医薬品化合物の生合成機構の解明2022
- Author(s)
  淡川孝義, バラレナ, 白井孝平, 森貴裕、阿部郁朗
- Organizer
  第36回日本放線菌学会
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 新規NAD/SAM代謝経路における生合成酵素の構造機能解明2022
- Author(s)
  白井孝平、レナバラ、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本生薬学会第68年会
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] β-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川　孝義
- Organizer
  Enzyme Mechanisms Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 新規NAD/SAM代謝経路における生合成酵素の構造機能解明2022
- Author(s)
  白井孝平、レナバラ、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本生薬学会第68年会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] β-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川　孝義
- Organizer
  NWO-JSPS Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] beta-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川孝義
- Organizer
  The 1st Japan/China Joint Young Researcher Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 補酵素NADを基質とする天然医薬品化合物の生合成機構の解明2022
- Author(s)
  淡川孝義, バラレナ, 白井孝平, 森貴裕、阿部郁朗
- Organizer
  第36回日本放線菌学会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] beta-NAD as a building block in natural product biosynthesis2022
- Author(s)
  淡川孝義
- Organizer
  Sapporo Summer Seminar on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05123
[Presentation] 抗腫瘍性天然物アルテミシジン生合成酵素の構造機能解明2022
- Author(s)
  白井孝平、レナバラ、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 抗腫瘍性天然物アルテミシジン生合成に関わるスルホンアミド骨格転移酵素の構造機能解明2021
- Author(s)
  白井　孝平、レナ　バラ、淡川　孝義、森　貴裕、阿部　郁朗
- Organizer
  日本生薬学会第67年会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 微生物由来医薬品骨格生合成酵素の発掘とその利用2021
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第141年会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] β-NAD as a building block in natural product biosynthesis2021
- Author(s)
  Lena Barra, Takayoshi Awakawa, Kohei Shirai, Ikuro Abe
- Organizer
  4th European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Aziridine formation by a Fe(II)/α-ketoglutarate dependent oxygenase and 2-aminoisobutyrate biosynthesis in fungi2021
- Author(s)
  Reito Bunno, Takayoshi Awakawa, Takahiro Mori, Ikuro Abe
- Organizer
  4th European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Heterodimeric Fe(II)/α-KG-dependent Oxygenases in Fungal Meroterpenoid Biosynthesis2021
- Author(s)
  Xinyang Li, Takayoshi Awakawa, Takahiro Mori, Ikuro Abe
- Organizer
  4th European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 放線菌由来抗腫瘍活性化合物アルテミシジンの生合成機構の解明2021
- Author(s)
  白井孝平、バラレナ、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] PKS-NRPSシステムにおけるポリケタイド合成酵素の精密機能解析2021
- Author(s)
  文野伶音、森貴裕、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 放線菌由来抗腫瘍活性化合物アルテミシジンの生合成機構の解明2021
- Author(s)
  白井孝平、バラレナ、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 微生物由来医薬品骨格生合成酵素の発掘とその利用2021
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第141年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] PKS-NRPSシステムにおけるポリケタイド合成酵素の精密機能解析2021
- Author(s)
  文野伶音、森貴裕、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Investigation of the α-ketoglutarate-dependent oxygenase reaction in the orthoester-containing fungal meroterpenoid biosynthesis2021
- Author(s)
  劉薇、白桐暄、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 2-アミノイソ酪酸生合成経路においてアジリジン形成反応を触媒するα-ケトグルタル酸依存性酸化酵素の同定2021
- Author(s)
  文野伶音、淡川孝義、森貴裕、阿部郁朗
- Organizer
  日本生薬学会第67年会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Engineered biosynthesis of pharmaceutically important compounds2021
- Author(s)
  淡川　孝義
- Organizer
  AIMECS2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] The enzymatic reactions in sulfonamide natural product biosynthesis2021
- Author(s)
  淡川　孝義
- Organizer
  PACIFICHEM2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] 新規補酵素由来天然物の生合成機構の解析2021
- Author(s)
  淡川　孝義、レナバラ、白井孝平、阿部郁朗
- Organizer
  第35回日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Aziridine formation by a Fe(II)/α-ketoglutarate dependent oxygenase and 2-aminoisobutyrate biosynthesis in fungi2021
- Author(s)
  Reito Bunno, Takayoshi Awakawa, Takahiro Mori, Ikuro Abe
- Organizer
  The Chemistry and Biology of Natural Products Symposium XIV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21363
[Presentation] Investigation of the α-ketoglutarate-dependent oxygenase reaction in the orthoester-containing fungal meroterpenoid biosynthesis2021
- Author(s)
  劉薇、白桐暄、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物からの医薬品骨格生合成酵素の発掘と利用2020
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第140年会(学術奨励賞受賞講演)
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Penicillium arizonense由来メロテルペノイドAustalideの生合成研究2020
- Author(s)
  劉薇、白桐暄、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 微生物からの医薬品骨格生合成酵素の発掘と利用2020
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物二次代謝酵素の精密機能解析と物質生産に関する酵素工学研究2020
- Author(s)
  淡川　孝義
- Organizer
  2020年度酵素工学研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] Biosynthetic study of sulfonamide natural product antibiotics2020
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 非リボソーマルペプチド-ポリケタイド合成酵素モジュール相互作用の精密解析2020
- Author(s)
  文野伶音、森貴裕、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 非リボソーマルペプチド-ポリケタイド合成酵素モジュール相互作用の精密解析2020
- Author(s)
  文野伶音、森貴裕、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Biosynthetic study of sulfonamide natural product antibiotics2020
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] Penicillium arizonense由来メロテルペノイドAustalideの生合成研究2020
- Author(s)
  劉薇、白桐暄、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Biosynthetic study of sulfonamide natural product antibiotics2020
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物二次代謝酵素の精密機能解析と物質生産に関する酵素工学研究2020
- Author(s)
  淡川　孝義
- Organizer
  2020年度酵素工学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Penicillium arizonense由来メロテルペノイドAustalideの生合成研究2020
- Author(s)
  劉薇、白桐暄、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 微生物からの医薬品骨格生合成酵素の発掘と利用2020
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 天然由来スルホンアミド抗生物質の生合成研究2020
- Author(s)
  淡川　孝義、バラ　レナ、胡　志娟、何　海兵、Zhai Rui、森　貴裕、阿部　郁朗
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 天然由来スルホンアミド抗生物質の生合成研究2020
- Author(s)
  淡川　孝義、バラ　レナ、胡　志娟、何　海兵、Zhai Rui、森　貴裕、阿部　郁朗
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 非リボソーマルペプチド-ポリケタイド合成酵素モジュール相互作用の精密解析2020
- Author(s)
  文野伶音、森貴裕、淡川孝義、阿部郁朗
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] アスコフラノン生合成の天然物化学糸状菌メロテルペノイドの生合成反応の多様性2019
- Author(s)
  淡川　孝義
- Organizer
  KISTECセミナー(神奈川)
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Function and structure analysis of a multifunctional cupin dioxygenase in sulfonamide biosynthesis2019
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  Gordon Conference Enzyme
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物からの新規医薬品骨格生合成酵素の発掘と利用2019
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] アスコフラノン生合成の天然物化学糸状菌メロテルペノイドの生合成反応の多様性2019
- Author(s)
  淡川孝義
- Organizer
  KISTECセミナー(神奈川)
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution2019
- Author(s)
  Takayoshi Awakawa
- Organizer
  2nd China-Japanese Joint Symposium on the Biosynthesis of Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution2019
- Author(s)
  Takayoshi Awakawa
- Organizer
  2nd China-Japanese Joint Symposium on the Biosynthesis of Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] スルホンアミド抗生物質の生合成研究2019
- Author(s)
  淡川孝義、胡志娟、何海兵、森貴裕、阿部郁朗
- Organizer
  食品薬学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] S-N結合形成に関わる新規多段階型酸化酵素の同定2019
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] スルホンアミド抗生物質の生合成研究2019
- Author(s)
  淡川孝義、胡志娟、何海兵、森貴裕、阿部郁朗
- Organizer
  第八回食品薬学シンポジウム
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] S-N結合形成に関わる新規多段階型酸化酵素の同定2019
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 微生物医薬品骨格生合成酵素の発掘とその利用2019
- Author(s)
  淡川孝義
- Organizer
  日本薬学会関東支部会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 放線菌アルカロイド生合成酵素の発掘および物質生産2019
- Author(s)
  淡川　孝義
- Organizer
  第３４回放線菌学会(学術奨励賞受賞講演)
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 微生物医薬品骨格生合成酵素の発掘とその利用2019
- Author(s)
  淡川　孝義
- Organizer
  日本薬学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Function and structure analysis of a multifunctional cupin dioxygenase in sulfonamide biosynthesis2019
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  Gordon Conference Enzyme
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] Function and structure analysis of a multifunctional cupin dioxygenase in sulfonamide biosynthesis2019
- Author(s)
  Takayoshi Awakawa, Zhijuan Hu, Haibing He, Takahiro Mori, Ikuro Abe
- Organizer
  Gordon Conference Enzyme
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] アスコフラノン生合成の天然物化学糸状菌メロテルペノイドの生合成反応の多様性2019
- Author(s)
  淡川孝義
- Organizer
  KISTECセミナー(神奈川)
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 放線菌アルカロイド生合成酵素の発掘および物質生産2019
- Author(s)
  淡川孝義
- Organizer
  第３４回放線菌学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物医薬品骨格生合成酵素の発掘とその利用2019
- Author(s)
  淡川孝義
- Organizer
  日本薬学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] スルホンアミド抗生物質の生合成研究2019
- Author(s)
  淡川　孝義、胡　志娟、何　海兵、森　貴裕、阿部　郁朗
- Organizer
  第八回食品薬学シンポジウム
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 放線菌アルカロイド生合成酵素の発掘および物質生産2019
- Author(s)
  淡川孝義
- Organizer
  第３４回放線菌学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04641
[Presentation] 微生物からの新規医薬品骨格生合成酵素の発掘と利用2019
- Author(s)
  淡川孝義
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] NRPS-PKSモジュール酵素リプログラミングによる新規デプシペプチド生産2018
- Author(s)
  淡川孝義、藤岡拓真、張驪駻、星野翔太郎、胡志娟、橋本絢子、小曽根郁子、池田治生、新家一男、劉文、阿部郁朗
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] メロテルペノイドVerruculide A/Chrodrimanin Aの生合成研究2018
- Author(s)
  白桐暄, 全智揚, 淡川孝義, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 放線菌由来スルホンアミド含有アルカロイドの生合成研究2018
- Author(s)
  淡川孝義、胡志娟、阿部郁朗
- Organizer
  第33回日本放線菌学会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 放線菌由来アルカロイドSB-203208の生合成研究2018
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  日本農芸化学会2018大会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Hapalindole/ambiguine生合成に関わるプレニル基転移酵素AmbP1のX線構造解析2018
- Author(s)
  淡川孝義, 中嶋優, Chin Piow WONG, 森貴裕, Xinyu LIU, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] スルホンアミド類天然物SB－203207とSB－203208の生合成研究2018
- Author(s)
  胡志娟, 淡川孝義, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 放線菌由来アルカロイドSB-203208の生合成研究2018
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  日本農芸化学会2018大会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] メロテルペノイドVerruculide A/Chrodrimanin Aの生合成研究2018
- Author(s)
  白桐暄, 全智揚, 淡川孝義, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] NRPS-PKSモジュール酵素リプログラミングによる新規デプシペプチド生産2018
- Author(s)
  淡川孝義、藤岡拓真、張驪駻、星野翔太郎、胡志娟、橋本絢子、小曽根郁子、池田治生、新家一男、劉文、阿部郁朗
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 微生物アルカロイド生合成経路の開拓と物質生産への応用2018
- Author(s)
  淡川孝義
- Organizer
  高磁場・高感度NMR利活用促進のための天然物分野シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] NRPS-PKSモジュール酵素リプログラミングによる新規デプシペプチド生産2018
- Author(s)
  淡川孝義、藤岡拓真、張驪駻、星野翔太郎、胡志娟、橋本絢子、小曽根郁子、池田治生、新家一男、劉文、阿部郁朗
- Organizer
  第22回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Two distinct substrate binding modes for the normal and reverse prenylations of hapaindoles by the prenyltransferase AmbP32018
- Author(s)
  Chin Piow WONG, 淡川孝義, 中嶋優, 森貴裕, Xinyu LIU, 森田洋行, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Hapalindole/ambiguine生合成に関わるプレニル基転移酵素AmbP1のX線構造解析2018
- Author(s)
  淡川孝義, 中嶋優, Chin Piow WONG, 森貴裕, Xinyu LIU, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 複合培養法を利用した希少放線菌からの生物活性物質探索2018
- Author(s)
  星野翔太郎, 淡川孝義, 浅水俊平, 尾仲宏康, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 放線菌由来スルホンアミド含有アルカロイドの生合成研究2018
- Author(s)
  淡川孝義、胡志娟、阿部郁朗
- Organizer
  第33回日本放線菌学会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Two distinct substrate binding modes for the normal and reverse prenylations of hapaindoles by the prenyltransferase AmbP32018
- Author(s)
  Chin Piow WONG, 淡川孝義, 中嶋優, 森貴裕, Xinyu LIU, 森田洋行, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 複合培養法を利用した希少放線菌からの生物活性物質探索2018
- Author(s)
  星野翔太郎, 淡川孝義, 浅水俊平, 尾仲宏康, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] スルホンアミド類天然物SB－203207とSB－203208の生合成研究2018
- Author(s)
  胡志娟, 淡川孝義, 阿部郁朗
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] NRPS-PKSモジュール酵素リプログラミングによる新規デプシペプチド生産2018
- Author(s)
  淡川孝義、藤岡拓真、張驪駻、星野翔太郎、胡志娟、橋本絢子、小曽根郁子、池田治生、新家一男、劉文、阿部郁朗
- Organizer
  第22回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 微生物アルカロイド生合成経路の開拓と物質生産への応用2018
- Author(s)
  淡川孝義
- Organizer
  高磁場・高感度NMR利活用促進のための天然物分野シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Biosynthesis of SB-203207 and SB-2032082017
- Author(s)
  Takayoshi Awakawa
- Organizer
  Gordon conference, GRC Enzyme&co-factor
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] 放線菌由来アルカロイドSB-203208の生合成研究2017
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  第32回日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] Biosynthesis of teleocidin B, a protein kinase C activator with unique indole terpenoid structure2017
- Author(s)
  Takayoshi Awakawa
- Organizer
  LRIPF Meeting (桂林, 中国)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Biosynthesis of SB-203207 and SB-2032082017
- Author(s)
  Takayoshi Awakawa
- Organizer
  Gordon conference, GRC Enzyme&co-factor（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 放線菌由来アルカロイドSB-203208の生合成研究2017
- Author(s)
  淡川孝義, 胡志娟, 阿部郁朗
- Organizer
  第32回日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-17H04763
[Presentation] Biosynthesis of teleocidin B, a protein kinase C activator with unique indole terpenoid structure2017
- Author(s)
  Takayoshi Awakawa
- Organizer
  LRIPF Meeting (桂林, 中国)（招待講演）（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0095
[Presentation] 遺伝子解析に基づくポリエン系化合物の立体配置決定法の確立2016
- Author(s)
  張驪駻、秦斌、淡川孝義、岡田正弘、脇本敏幸、阿部郁朗
- Organizer
  第136回日本薬学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26560428
[Presentation] 放線菌異種発現系を用いた新規teleocidin類アナログの創出2014
- Author(s)
  星野翔太郎, 張驪駻, 淡川孝義, 伊藤卓也, 脇本敏幸, 阿部郁朗
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] 放線菌由来新規プレニルトランスフェラーゼTldCとMpnDのX線結晶構造解析2014
- Author(s)
  森貴裕、張驪駻、淡川孝義、脇本敏幸、森田洋行、阿部郁朗
- Organizer
  酵素工学研究会　第70回講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] 放線菌由来新規プレニルトランスフェラーゼTldCとMpnDのX線結晶構造解析2014
- Author(s)
  森貴裕、張驪駻、淡川孝義、脇本敏幸、森田洋行、阿部郁朗
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] Functional analyses of novel indole prenyltransferases2014
- Author(s)
  森貴裕、張驪駻、淡川孝義、脇本敏幸、森田洋行、阿部郁朗
- Organizer
  Marine Natural Products Gordon Research Conference.
- Place of Presentation
  Ventura, California, US.
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] LC-MSによる渦鞭毛藻由来ポリケタイド合成酵素の検出2013
- Author(s)
  淡川孝義、Ioana NTAI、佐竹真幸、Neil KELLEHER、橘和夫、阿部郁朗
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-24651239
[Presentation] Functional analysis of prenyltransferase TldC2013
- Author(s)
  森貴裕、張驪駻、淡川孝義、伊藤卓也、浅川義範、阿部郁朗,
- Organizer
  1st European Conference on Natural Products
- Place of Presentation
  Frankfurt am Main, Germany
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] 放線菌由来新規インドールプレニルトランスフェラーゼTldCとMpnDのX線結晶構造解析
- Author(s)
  森　貴裕、張　驪駻、淡川　孝義、脇本　敏幸、森田　洋行、阿部　郁朗
- Organizer
  第29回日本放線菌学会大会
- Place of Presentation
  茨城県つくば市
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] Cyclohexene ring formation facilitated by methylation of the prenyl chain in teleocidin B4 biosynthesis
- Author(s)
  Awakawa, T., Mori, T., Zhang, L., Wakimoto, T., Hoshino, S., Ito, T., Ishikawa, J., Tanner, M. E., Abe, I.
- Organizer
  248th ACS National Meeting & Exposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-08-10 – 2014-08-14
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] Teleocidin類の生合成機構の解明
- Author(s)
  森　貴裕、淡川　孝義、張　驪駻、星野　翔太郎、脇本　敏幸、森田　洋行、伊藤　卓也、石川　淳、阿部　郁朗
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県高知市
- Year and Date
  2014-10-15 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis
- Author(s)
  Awakawa, T., Mori, T., Zhang, L., Wakimoto, T., Hoshino, S., Ito, T., Ishikawa, J., Tanner, M. E., Abe, I.
- Organizer
  Natural Product Discovery & Development in the Post Genomic Era by Society for industrial microbiology and biotechnology
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-01-11 – 2015-01-14
- Data Source
  KAKENHI-PROJECT-25750382
[Presentation] LC-MSによる渦鞭毛藻由来ポリケタイド合成酵素の検出
- Author(s)
  淡川孝義、Ioana NTAI、佐竹真幸、Neil KELLEHER、橘和夫、阿部郁朗
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24651239

1. ABE IKURO (40305496)

# of Collaborated Projects: 7 results

# of Collaborated Products: 38 results
2. MATSUDA Yudai (10720766)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. WAKIMOTO Toshiyuki (70363900)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. MORITA Hiroyuki (20416663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 森貴裕 (60734564)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. 牛丸理一郎 (10873648)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. SUGIO Shigetoshi (10537343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NOGUCHI Hiroshi (60126141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KUSHIRO Testuo (80373299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SENDA Toshiya (30272868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中村仁美 (90800657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡田正弘 (40377792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 葛山智久 (30280952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 内山真伸 (00271916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 丸山千登勢 (20452120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 寺田透 (40359641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡辺賢二 (50360938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 勝山陽平 (50646437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山崎真巳 (70222370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大栗博毅 (80311546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 荘司長三 (90379587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. CUI JINSHENG

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 安達成彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 城戸康年

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 工藤雄大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. YANG Xiao-Long

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Awakawa Takayoshi 淡川 孝義

AWAKAWA Takayoshi 淡川 孝義

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生体分子骨格薬用活性化合物の生物合成科学Principal Investigator

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補酵素NAD由来新規天然物生合成経路由来活性分子の創出Principal Investigator

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酵素機能発掘と合成生物学による次世代型物質生産系の構築Principal Investigator

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医薬品骨格含有新規天然物群の生合成機構解明および改変による薬用活性化合物の創出Principal Investigator

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酵素機能改変による新規活性アルカロイド生産系の構築Principal Investigator

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The engineering of terpene cyclase based on the knowledge on control of transition statePrincipal Investigator

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Creation of non-natural enzyme reactions based on three-dimensional structure and expression screeningPrincipal Investigator

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Functional analyses of teleocidin B biosynthetic enzymesPrincipal Investigator

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Awakawa Takayoshi 淡川孝義

AWAKAWA Takayoshi 淡川孝義