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Hayashi Manabu  林 学

ORCIDConnect your ORCID iD *help
Researcher Number 80745787
Affiliation (Current) 2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2020 – 2023: 福島県立医科大学, 医学部, 助教
2018 – 2019: 福島県立医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Basic Section 49070:Immunology-related
Keywords
Principal Investigator
非アルコール性脂肪肝炎 / MASP-3 / 補体 / 非アルコール性脂肪肝 / 非アルコール性脂肪肝疾患 / 線維化 / MASP-1 / MASP / 脂肪肝
Except Principal Investigator
口腔・腸内細菌 … More / Veillonella / 濾胞性ヘルパーT細胞 / 口腔・腸内細菌叢 / 腸内細菌叢 / Tfh細胞 / Veillonella dispar / 腸内細菌 / 自己免疫性肝炎 / 補体 / セリンプロテアーゼ / 補体活性化 / レクチン経路の糖鎖認識分子 / 補体レクチン経路 / 認識分子 / レクチン経路 / 第二経路 / MASP-3 / 補体因子 Less
  • Research Projects

    (4 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (6 People)
  •  非アルコール性脂肪肝疾患の腸肝軸へ対する補体活性化因子MASP-3の機能解明Principal Investigator

    • Principal Investigator
      林 学
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Fukushima Medical University
  •  口腔・腸内細菌と濾胞性ヘルパーT細胞を標的とした自己免疫性肝炎の病態解明

    • Principal Investigator
      阿部 和道
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Fukushima Medical University
  •  Elucidation of the activation mechanism of the complement factor MASP-3 of the alternative complement pathway

    • Principal Investigator
      Sekine Hideharu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Fukushima Medical University
  •  Association between complement activation pathways and nonalcoholic fatty liver diseasePrincipal Investigator

    • Principal Investigator
      Hayashi Manabu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Fukushima Medical University

All 2020 2019

All Journal Article

  • [Journal Article] A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways2020

    • Author(s)
      Takasumi M, Omori T, Machida T, Ishida Y, Hayashi M, Suzuki T, Homma Y, Endo Y, Takahashi M, Ohira H, Fujita T, Sekine H
    • Journal Title

      FASEB J

      Volume: 34 Issue: 5 Pages: 6598-6612

    • DOI

      10.1096/fj.201902475r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
  • [Journal Article] Association between serum ficolin-1 level and disease progression in primary biliary cholangitis2020

    • Author(s)
      Hayashi Manabu、Abe Kazumichi、Fujita Masashi、Takahashi Atsushi、Sekine Hideharu、Ohira Hiromasa
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 9 Pages: e0238300-e0238300

    • DOI

      10.1371/journal.pone.0238300

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07610
  • [Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019

    • Author(s)
      Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
    • Journal Title

      The Journal of Immunology

      Volume: 203 Issue: 6 Pages: 1411-1416

    • DOI

      10.4049/jimmunol.1900605

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-18K08895, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K15789, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K16975
  • [Journal Article] Response to comment on “Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway”2019

    • Author(s)
      Takeshi Machida, Manabu Hayashi, Teizo Fujita, and Hideharu Sekine
    • Journal Title

      The Journal of Immunology

      Volume: 203 Issue: 12 Pages: 3091-3092

    • DOI

      10.4049/jimmunol.1901087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-19K07610
  • 1.  Sekine Hideharu (40363759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  町田 豪 (80583632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  阿部 和道 (30468128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  高橋 敦史 (40404868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  大平 弘正 (90274951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  大森 智子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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