Hayashi Manabu 林学

Researcher Number	80745787
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 福島県立医科大学, 医学部, 助教 2018 – 2019: 福島県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 49070:Immunology-related
Keywords	Principal Investigator 非アルコール性脂肪肝炎 / MASP-3 / 補体 / 非アルコール性脂肪肝 / 非アルコール性脂肪肝疾患 / 線維化 / MASP-1 / MASP / 脂肪肝 Except Principal Investigator 口腔・腸内細菌 … More / Veillonella / 濾胞性ヘルパーT細胞 / 口腔・腸内細菌叢 / 腸内細菌叢 / Tfh細胞 / Veillonella dispar / 腸内細菌 / 自己免疫性肝炎 / 補体 / セリンプロテアーゼ / 補体活性化 / レクチン経路の糖鎖認識分子 / 補体レクチン経路 / 認識分子 / レクチン経路 / 第二経路 / MASP-3 / 補体因子 Less

非アルコール性脂肪肝疾患の腸肝軸へ対する補体活性化因子MASP-3の機能解明Principal Investigator
- Principal Investigator
  
  林学
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Fukushima Medical University
口腔・腸内細菌と濾胞性ヘルパーT細胞を標的とした自己免疫性肝炎の病態解明
- Principal Investigator
  
  阿部和道
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Fukushima Medical University
Elucidation of the activation mechanism of the complement factor MASP-3 of the alternative complement pathway
- Principal Investigator
  
  Sekine Hideharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Fukushima Medical University
Association between complement activation pathways and nonalcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  Hayashi Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Fukushima Medical University

All 2020 2019

All Journal Article

[Journal Article] A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways2020
- Author(s)
  Takasumi M, Omori T, Machida T, Ishida Y, Hayashi M, Suzuki T, Homma Y, Endo Y, Takahashi M, Ohira H, Fujita T, Sekine H
- Journal Title
  
  FASEB J
  
  Volume: 34 Issue: 5 Pages: 6598-6612
- DOI
  10.1096/fj.201902475r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
[Journal Article] Association between serum ficolin-1 level and disease progression in primary biliary cholangitis2020
- Author(s)
  Hayashi Manabu、Abe Kazumichi、Fujita Masashi、Takahashi Atsushi、Sekine Hideharu、Ohira Hiromasa
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 9 Pages: e0238300-e0238300
- DOI
  10.1371/journal.pone.0238300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07610
[Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019
- Author(s)
  Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 6 Pages: 1411-1416
- DOI
  10.4049/jimmunol.1900605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-18K08895, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K15789, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K16975
[Journal Article] Response to comment on “Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway”2019
- Author(s)
  Takeshi Machida, Manabu Hayashi, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 12 Pages: 3091-3092
- DOI
  10.4049/jimmunol.1901087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-19K07610

1. Sekine Hideharu (40363759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 町田豪 (80583632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 阿部和道 (30468128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 高橋敦史 (40404868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大平弘正 (90274951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大森智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Manabu 林 学

Research Projects

Research Products

Co-Researchers

非アルコール性脂肪肝疾患の腸肝軸へ対する補体活性化因子MASP-3の機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔・腸内細菌と濾胞性ヘルパーT細胞を標的とした自己免疫性肝炎の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the activation mechanism of the complement factor MASP-3 of the alternative complement pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association between complement activation pathways and nonalcoholic fatty liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between serum ficolin-1 level and disease progression in primary biliary cholangitis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response to comment on “Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway”2019

Author(s)

Journal Title

DOI

Data Source

Hayashi Manabu 林学