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Okamoto Akinao  岡本 晃直

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Akinao Okamoto  岡本 晃直

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Researcher Number 80775049
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2018 – 2024: 藤田医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Basic Section 52010:General internal medicine-related
Except Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords
Principal Investigator
不明熱 / 悪性リンパ腫 / リキッドバイオプシー / NGS / Droplet digital PCR / Liquid biopsy / 血管内リンパ腫 / リキッド・バイオプシー / droplet digital PCR / liquid biopsy / Lymphoma / cell free DNA / Oncology … More
Except Principal Investigator
… More 液性免疫 / SARS-CoV-2 Less
  • Research Projects

    (3 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (20 People)
  •  多角的なSARS-CoV-2免疫獲得状況の調査研究

    • Principal Investigator
      藤垣 英嗣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Fujita Health University
  •  悪性リンパ腫疑い不明熱患者に対するリキッドバイオプシーによる診断法の確立Principal Investigator

    • Principal Investigator
      岡本 晃直
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Fujita Health University
  •  Liquid Biopsy for the Diagnosis of Malignant Lymphoma in Patients with Fever of Unknown OriginPrincipal Investigator

    • Principal Investigator
      Akinao Okamoto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Fujita Health University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

  • [Journal Article] EBV+ nodal T/NK-cell lymphoma associated with clonal hematopoiesis and structural variations of the viral genome2024

    • Author(s)
      Kato Seiichi、Hamada Motoharu、Okamoto Akinao、Yamashita Daisuke、Miyoshi Hiroaki、Arai Haruto、Satou Akira、Gion Yuka、Sato Yasuharu、Tsuyuki Yuta、Miyata-Takata Tomoko、Takata Katsuyoshi、Asano Naoko、Takahashi Emiko、Ohshima Koichi、Tomita Akihiro、Hosoda Waki、Nakamura Shigeo、Okuno Yusuke
    • Journal Title

      Blood Advances

      Volume: Epub Issue: 9 Pages: 2138-2147

    • DOI

      10.1182/bloodadvances.2023012019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K06920, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K21374, KAKENHI-PROJECT-23K24140
  • [Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023

    • Author(s)
      Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
    • Journal Title

      International Journal of Hematology

      Volume: 118 Issue: 4 Pages: 462-471

    • DOI

      10.1007/s12185-023-03648-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
  • [Journal Article] Five-year follow-up of a phase II study of DA-EPOCH-R with high-dose MTX in CD5-positive DLBCL.2023

    • Author(s)
      Miyazaki Kana、Sakai Rika、Iwaki Noriko、et al.
    • Journal Title

      Cancer Science

      Volume: - Issue: 6 Pages: 2689-2691

    • DOI

      10.1111/cas.15784

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-21K08381
  • [Journal Article] Utility of cerebrospinal fluid liquid biopsy in distinguishing <scp>CNS</scp> lymphoma from cerebrospinal infectious/demyelinating diseases2023

    • Author(s)
      Iriyama Chisako、Murate Kenichiro、Iba Sachiko、Okamoto Akinao、Goto Naoe、Yamamoto Hideyuki、Kato Toshiharu、Mihara Keichiro、Miyama Takahiko、Hattori Keiko、Kajiya Ryoko、Okamoto Masataka、Mizutani Yasuaki、Yamada Seiji、Tsukamoto Tetsuya、Hirose Yuichi、Mutoh Tatsuro、Watanabe Hirohisa、Tomita Akihiro
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 16 Pages: 16972-16984

    • DOI

      10.1002/cam4.6329

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K07446, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K24297
  • [Journal Article] Acute fulminant intravascular hemolysis induced by Clostridium perfringens in a symptomatic multiple myeloma patient under immuno-chemotherapy2022

    • Author(s)
      Yamamoto Hideyuki、Mizutani Yuki、Iriyama Chisako、Goto Naoe、Okamoto Akinao、Kato Toshiharu、Shintani Chiyo、Yamamoto Naoki、Miyama Takahiko、Mihara Keichiro、Okamoto Masataka、Tomita Akihiro
    • Journal Title

      Annals of Hematology

      Volume: 101 Issue: 12 Pages: 2813-2815

    • DOI

      10.1007/s00277-022-05010-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K24297
  • [Journal Article] CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma2022

    • Author(s)
      Okamoto Akinao、Fujigaki Hidetsugu、Iriyama Chisako、Goto Naoe、Yamamoto Hideyuki、Mihara Keichiro、Inaguma Yoko、Miura Yasuo、Furukawa Katsuya、Yamamoto Yukiya、Akatsuka Yoshiki、Kasahara Senji、Miyao Kotaro、Kajiya Ryoko、Okamoto Masataka、Saito Kuniaki、Tomita Akihiro
    • Journal Title

      Blood Advances

      Volume: 6 Issue: 11 Pages: 3230-3233

    • DOI

      10.1182/bloodadvances.2021006302

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-23K24297
  • [Journal Article] Correction to: Detection of circulating tumor DNA in cerebrospinal fluid prior to diagnosis of spinal cord lymphoma by flow cytometric and cytologic analyses2021

    • Author(s)
      Iriyama Chisako、Murate Kenichiro、Iba Sachiko、Okamoto Akinao、Yamamoto Hideyuki、Kanbara Ayana、Sato Akane、Iwata Emiko、Yamada Ryuta、Okamoto Masataka、Watanabe Hirohisa、Mutoh Tatsuro、Tomita Akihiro
    • Journal Title

      Annals of Hematology

      Volume: 101 Issue: 5 Pages: 1161-1162

    • DOI

      10.1007/s00277-021-04722-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Journal Article] Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma2021

    • Author(s)
      Shimada Kazuyuki、Yoshida Kenichi、Suzuki Yasuhiro、Iriyama Chisako、Inoue Yoshikage、Sanada Masashi、Kataoka Keisuke、Yuge Masaaki、Takagi Yusuke、Kusumoto Shigeru、Masaki Yasufumi、Ito Takahiko、Inagaki Yuichiro、Okamoto Akinao、Kuwatsuka Yachiyo、Nakatochi Masahiro、Shimada Satoko、Miyoshi Hiroaki et al.
    • Journal Title

      Blood

      Volume: 137 Issue: 11 Pages: 1491-1502

    • DOI

      10.1182/blood.2020007245

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-21K16279
  • [Journal Article] Predictive and risk factor analysis for bloodstream infection in high-risk hematological patients with febrile neutropenia: post-hoc analysis from a prospective, large-scale clinical study2021

    • Author(s)
      Okamoto Akinao、Kanda Yoshinobu、Kimura Shun-ichi、Oyake Tatsuo、Tamura Kazuo、from the Japan Febrile Neutropenia Study Group
    • Journal Title

      International Journal of Hematology

      Volume: 114 Issue: 4 Pages: 472-482

    • DOI

      10.1007/s12185-021-03183-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Journal Article] D-Index-Guided Early Antifungal Therapy Versus Empiric Antifungal Therapy for Persistent Febrile Neutropenia: A Randomized Controlled Noninferiority Trial.2020

    • Author(s)
      Kanda Y1, Kimura S, Iino M, Fukuda T, Sakaida E, Oyake T, Yamaguchi H, Fujiwara SI, Jo Y, Okamoto A, Fujita H, Takamatsu Y, Saburi Y, Matsumura I, Yamanouchi J, Shiratori S, Gotoh M, Nakamura S, Tamura K
    • Journal Title

      J Clin Oncol.

      Volume: Epub Issue: 8 Pages: 815-822

    • DOI

      10.1200/jco.19.01916

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Journal Article] Truncated RUNX1 generated from the fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances sensitivity to granulocyte colony-stimulating factor2020

    • Author(s)
      Abe A, Yamamoto Y, Katsumi A, Yamamoto H, Okamoto A, Inaguma Y, Iriyama C, Tokuda M, Okamoto M, Emi N, Tomita A.
    • Journal Title

      Cytogenetic and Genome Research

      Volume: - Issue: 5 Pages: 255-263

    • DOI

      10.1159/000508012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18K15402
  • [Journal Article] Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma arising in patient with a history of EBV-positive mucocutaneous ulcer and EBV-positive nodal polymorphous B-lymphoproliferative disorder2019

    • Author(s)
      Daroontum T, Kohno K, Inaguma Y, Okamoto A, Okamoto M, Kimura Y, Nagahama M, Sakakibara A, Satou A, Nakamura S
    • Journal Title

      Pathology International

      Volume: 69 Issue: 1 Pages: 37-41

    • DOI

      10.1111/pin.12738

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Journal Article] Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma.2018

    • Author(s)
      Higuchi H, Yamakawa N, Imadome KI, Yahata T, Kotaki R, Ogata J, Kakizaki M, Fujita K, Lu J, Yokoyama K, Okuyama K, Sato A, Takamatsu M, Kurosaki N, Alba SM, Azhim A, Horie R, Watanabe T, Kitamura T, Ando K, Kashiwagi T, Matsui T, Okamoto A, Handa H, Kuroda M, Nakamura N, Kotani A.
    • Journal Title

      Blood

      Volume: 131 Issue: 23 Pages: 2552-2567

    • DOI

      10.1182/blood-2017-07-794529

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08728, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-17H04067, KAKENHI-PROJECT-17H04212
  • [Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017

    • Author(s)
      Abe A, Yamamoto Y, Katsumi A, Okamoto A, Tokuda M, Inaguma Y, Yamamoto K, Yanada M, Kanie T, Tomita A, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
    • Journal Title

      Int J Hematol.

      Volume: - Issue: 2 Pages: 208-212

    • DOI

      10.1007/s12185-017-2387-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-17K07182, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-16K09860
  • [Patent] 不明熱患者のB細胞リンパ腫診断補助キットおよび情報提供方法2022

    • Inventor(s)
      岡本晃直
    • Industrial Property Rights Holder
      岡本晃直
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Patent] 不明熱患者のB細胞リンパ腫診断補助キットおよび情報提供方法2022

    • Inventor(s)
      岡本晃直
    • Industrial Property Rights Holder
      学校法人 藤田学園
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Acquisition Date
      2024
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Presentation] Prospective Study of the Usefulness of Liquid Biopsy in Patients with Unknown Fever Suspected of Malignant Lymphoma2022

    • Author(s)
      Akinao Okamoto, Masashi Sanada, Takahiko Yasuda, Seiichi Kato, Akihiro Tomita et al.
    • Organizer
      64th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Presentation] Liquid biopsy for suspicious lymphoma patients with fever of unknown origin2022

    • Author(s)
      Akinao Okamoto, Masashi Sanada, Takahiko Yasuda, Seiichi Kato, Akihiro Tomita et al.
    • Organizer
      第84回 日本血液学会総会
    • Data Source
      KAKENHI-PROJECT-21K08381
  • [Presentation] Liquid biopsyが補助診断に有効であった血管内大細胞型B細胞リンパ腫の一例2021

    • Author(s)
      岡本晃直、真田昌、齊藤繁紀、伊庭佐知子、齊藤統子、山本秀行、徳田倍将、水野紘樹、後藤尚江、入山智沙子、中村栄男、冨田章裕
    • Organizer
      第61回 リンパ網内系学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Presentation] 初発時の遺伝子変異解析が病型診断に有用であったろ胞性ヘルパーT細胞表現型を有するPTCLの1例2021

    • Author(s)
      加藤駿晴、岡本晃直 、入山智沙子 、安田貴彦、後藤尚絵、加留部謙之介、三好寛明、眞田昌、堀部敬三、冨田章裕
    • Organizer
      第10回 日本血液学会東海地方会
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Presentation] Detection of central nervous system lymphomas by genetic analyses using cerebrospinal fluid2020

    • Author(s)
      Chisako Iriyama,Kennichiro Murate,Sachiko Iba,Akinao Okamoto, Hideyuki Yamamoto,Masutaka Tokuda,Yukiya Yamamoto, Masataka Okamoto,Hirohisa Watanabe,Akihiro Tomita
    • Organizer
      第82回 日本血液学会
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Presentation] Detailed Assessment of Blood Culture and Clinical Factors in Febrile Neutropenia Patients with High-Risk Hematological Malignancy in Japan: A Subgroup Analysis of the Cedmic Trial2020

    • Author(s)
      Okamoto A, Kanda Y, Kimura SI, Oyake T, Tamura K
    • Organizer
      62nd ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Presentation] 髄液のフローサイトメトリーおよび遺伝子検査が診断に有用であった脊髄B細胞性悪 性リンパ腫の一例2019

    • Author(s)
      齋藤聡一郎,入山智沙子,村手健一郎,武藤多津郎,佐藤あかね, 神原彩那,岡本晃直,稲熊容子,岡部麻子,山田勢至,浦野誠, 金田典雄,恵美宜彦,岡本昌隆,冨田章裕
    • Organizer
      日本リンパ網内系学会
    • Data Source
      KAKENHI-PROJECT-18K15402
  • [Presentation] 中枢浸潤リンパ腫において,髄液中可溶性IL-2Rは上昇する2019

    • Author(s)
      岡本晃直,入山智沙子,稲熊容子,岡本昌隆,冨田章裕
    • Organizer
      日本リンパ網内系学会
    • Data Source
      KAKENHI-PROJECT-18K15402
  • 1.  真田 昌 (20529044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  安田 貴彦 (20723977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  加藤 省一 (30584669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  藤垣 英嗣 (00612631)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  山本 康子 (00331869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  近藤 征史 (00378077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  長谷川 みどり (40298518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  成瀬 寛之 (50319266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  坪井 直毅 (50566958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  古関 竹直 (70850551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  齋藤 邦明 (80262765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  伊藤 弘康 (80373075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  冨田 章裕 (80378215)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KATSUMI Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  HORIE Ryouichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  葉名尻 良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  山本 幸也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  安部 明弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  恵美 宣彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  島田 和之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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