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NEMOTO Takayuki  根本 孝幸

… Alternative Names

根元 孝幸  ネモト タカユキ

Less
Researcher Number 90164665
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5007-6260
External Links
Affiliation (Current) 2025: 長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員
2025: 岩手医科大学, 歯学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2023: 岩手医科大学, 歯学部, 非常勤講師
2021 – 2023: 長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員
2014 – 2020: 長崎大学, 医歯薬学総合研究科(歯学系), 教授
2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 教授
2010 – 2012: 長崎大学, 大学院・医歯薬学総合研究科, 教授 … More
2009 – 2010: Nagasaki University, 医歯薬学総合研究科, 教授
2007: Nagasaki University, Graduate School of Biomedical Sciences, Professor
2005 – 2006: Nagasaki University, Graduate school of Biomedical Sciences, Department of Developmental and Reconstructive Medicine, Professor, 大学院医歯薬学総合研究科, 教授
2002 – 2005: K, Nagasaki University Graduate School of Biomedical Sciences Professor, 大学院・医歯薬学総合研究科, 教授
2001: 長崎大学, 歯学部, 教授
1999: Nagasaki University, School of Dentistry, Professor, 歯学部, 教授
1996 – 1998: 岩手医科大学, 歯学部, 助教授
1992 – 1995: 岩手医科大学, 歯学部, 講師
1991: 岩手医科大学, 歯学部・口腔生化学講座, 講師
1988: Iwate Medical University School of Dentistry assistant professor, 歯学部, 講師
1988: 岩手歯科大学, 歯学部, 講師
1987: 岩手医科大学, 歯学部・口腔生化学講座, 講師
1986: 岩手医科大学, 歯学部口腔生化学講座, 講師 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry / Basic Section 57010:Oral biological science-related / Biological Sciences
Except Principal Investigator
Functional basic dentistry / Functional basic dentistry / Orthodontics/Pediatric dentistry / Basic Section 57080:Social dentistry-related / Basic Section 57020:Oral pathobiological science-related / Surgical dentistry / Orthodontic/Pediatric dentistry / 矯正・小児・社会系歯学
Keywords
Principal Investigator
HSP90 / 分子シャペロン / ジペプチジルペプチダーゼ / 歯周病 / ドメイン構造 / ストレスタンパク質 / ジペプチド / 糖尿病 / ペプチダーゼ / DPP11 … More / DPP7 / Porphyromonas gingivalis / アミノ酸トランスポーター / 歯周病菌 / SNP / Hsp90 / HSP47 / molecular chaperone / ダイマー / EGF / 口腔細菌 / エキソペプチダーゼ / コラーゲン / ドメイン / HtpG / 全身性エリテマトーデス / アイソフォーム / タンパク代謝 / システインペプチダーゼ / セリンペプチダーゼ / アミノ酸 / タンパク分解 / ジペプチダーゼ / N末修飾 / 2型糖尿病 / ペプチドトランスポーター / ジペプチジルペプチダーぜ / DPP4 / ジププチド / トランスポーター / ペプチド代謝 / Trepanema forsythia / Prevotera intermedia / DPP / 耐糖試験 / インスリン / インクレチン / プロテアーゼ / 歯周病細菌 / Two-hybrid system / Isoform / Dimer / Molecular chaperone / ミスセンス変異 / 熱ショックタンパク質 / 2-ハイブリッドシステム / scar / domain structure / collagen / Hsp9Q / ペプチド結合 / 分子シャロペン / 瘢痕 / dimer / oligomer / systemic lupus erythematosus (SLE) / domain / stress protein / アイメフォーム / 骨芽細胞 / 自己抗体 / オリゴマー / dimerization / down-regulation / androgen response element / androgen receptor / submandibular gland / アンドロゲンレスポンスエレメント / 二量体化 / ダウンレギュレーション / アンドロゲン応答配列 / アンドロゲンレセプター / 顎下腺 / ジペプチジルププチダーゼ / 基質特異性 / アシルアミノペプチダーゼ / DPP5 / オリゴペプチダーゼ / 歯周病原性細菌 / タンパク質分解 / アミノ酸代謝 / アシルオリゴペプチジルペプチダーゼ / プロセシング / コアグラーゼ ポジティブ / グルタミン酸特異的プロテアーゼ / リコンビナント体 / グルタミン酸特異的 / セリンプロテアーゼ / 黄色ブドウ球菌 / ETA / 表皮剥脱毒素 / 熱傷様皮膚症候群 / Staphylococcus aureus / とびひ / ブドウ球菌性熱傷様皮膚症候群 / 自己重合 / クライアント / エピトープ / 蛋白質 / 分子認識 / 生体分子 / ストレス / HfpG / リコンビナントタンパク質 / サブユニット構造 / 転写因子 / ステロイドレセプター / ミネラルコルチコイドレセプター … More
Except Principal Investigator
ジペプチジルペプチダーゼ / EGF / 歯周病 / ERK / MEK / c-erbB2 / 歯根吸収 / 顎下腺 / 口腔細菌 / 歯周病菌 / Porphyromonas gingivalis / DPP / 糖尿病 / 生理活性ペプチド / インクレチン / DPP4 / ラット / in vitro / Hsp47 / root resorption / RANKL / p38 / MAPK / HSP90 / HtpG / Notch / osteoclasts / odontoclasts / 破骨細胞 / 破歯細胞 / c-fos / Androgen / アンドロゲン / EGF-receptor / ヒト顎下腺細胞株 / チロシンリン酸化 / オートクリン増殖 / EGFレセプター / ペプチダーゼ / P.gingivalis / P. gingivalis / 歯周病原菌 / アミノ酸代謝 / 歯周病原性細菌 / 酵素 / プロテアーゼ / dipeptidyl peptidase / 歯周病原性菌 / 血液凝固 / 細菌 / 恒常性 / エキソペプチダーゼ / 血糖値 / Pot / アミノ酸取り込み / 免疫電顕 / ジペプチド / DPP7 / 歯学 / 12/15LOX / 12/15LOX / 矯正治療 / 矯正力 / 歯の移動 / アラキドン酸カスケード / lipoxygenase / 12/15-LOX / ortohdontic / P. endodontalis / Porphyromonas属 / ポルフィロモナス属 / 歯周病原細菌 / 歯科 / 血糖 / GIP / GLP-1 / 口腔細菌叢 / 全身疾患 / インスリン / 2型糖尿病 / Nucleus / Rat / Mouse / Submandibular Glands / Androgen Receptor / グルココルチコイドレセプター / 肝臓 / アンドロゲン・レセプター / 核 / クロマチン / タンパク質 / 88-kDa / アンドロゲンレセプター / マウス / oral mucosa kerainocyte / fibroblast / GFP / 上皮細胞 / 線維芽細胞 / differentiation / 分化誘導 / stress / periodontitis / molecular chaperone / ストレス / 分子シャペロン / osteoblast / tooth development / プロテオミクス / Runx2 / DNAチップ / Notch1 / 歯芽発生 / 骨芽細胞 / 歯牙発生 / rootresorption / signaltransduction / stress protein / cytokine / 歯肉溝浸出液 / リコンビナント / TNF-alpha / IL-6 / IL-1 / HSP / シグナル伝達 / ストレスタンパク質 / サイトカイン / MAP-kinase / human salivary gland cell line / Transfection / Phosphorylation / MAP-キナーゼ / トランスフェクション / プロト癌遺伝子 / リン酸化シグナル / ヒト顎下腺細胞 / 高分子量EGF / EGFセレプター / Submandibular Gland / Steroid / Epidermal Growth Factor / Gene Expression / ステロイドホルモン / 遺伝子発現 / adenocarcinoma / autocrine growth / submandibular gland / 上皮成長因子レセプタ- / 上皮成長因子 / ヒト顎下腺 / 顎下腺細胞株 / 腺癌細胞 / オンコジン産物 / 糖非発酵性細菌 / 嫌気性菌 / ペリプラズム / 代謝活性 / トランスポーター / 蛍光 / レサズリン / ブドウ球菌 / 活性化 / 黄色ブドウ球菌 / 病原因子 / リコンビナントタンパク質 / セリンプロテアーゼ / 口腔癌 / 転写因子 / COUP-TF / RXR / RAR / レチノイドXレセプター / レチノイン酸レセプター Less
  • Research Projects

    (32 results)
  • Research Products

    (207 results)
  • Co-Researchers

    (39 People)
  •  Function of dipeptidyl-peptidases of periodontal bacteria in proliferation and pathogenicityPrincipal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Iwate Medical University
  •  Biochemical investigation of periodontitis severity caused by dipeptidyl peptidase from oral bacteria.

    • Principal Investigator
      西俣 はるか
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Nagasaki University
  •  Identification of cysteine peptidases that assure complete dipeptide production in periodontopathic bacteriaPrincipal Investigator

    • Principal Investigator
      Nemoto Takayuki
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Nagasaki University
  •  Novel modulating mechanisms of homeostasis by oral bacterial exopeptidases

    • Principal Investigator
      Ohara-Nemoto Yuko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Nagasaki University
  •  Involvement of 12 / 15-LOX with intracellular organelle degradation mechanism in root resorption

    • Principal Investigator
      HOTOKEZAKA Hitoshi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Nagasaki University
  •  Relations of periodontal diseases to systemic diseases and involvement of degradation of bioactive peptides by oral bacterial peptidases

    • Principal Investigator
      OHARA-NEMOTO Yuko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Exopeptidases from periodontopathic bacteria as risk factors of type-2 diabetes mellitusPrincipal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Pathogenic analysis of dipeptidyl-peptidase from Porphyromonas endodontalis

    • Principal Investigator
      NISHIMATA Haruka
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Nagasaki University
  •  Analysis of dipeptidyl peptidase gene group

    • Principal Investigator
      KOBAYAKAWA Takeshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Study of a novel enzymatic group of dipeptidyl peptidases and their cellular localization

    • Principal Investigator
      OHARA-NEMOTO Yuko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Mechanism of novel peptide metabolism system in periodontophatic bacteriumPrincipal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Study on the Glu-specific protease superfamily mediating dissociation of cell-cell adhesion

    • Principal Investigator
      NEMOTO Yuko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Therapeutic Establishment for Gingival Hyperplasia and Scar Formation by Use of Collagen-Digestible ProteasesPrincipal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  The study on molecular chaperones as a cancer therapy targetPrincipal Investigator

    • Principal Investigator
      TAKAYUKI Nemoto
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Relationship between Hsp47 and cornification mechanisms of oral mucosa keratinocytes after transplantation of cultured gingival fibroblasts

    • Principal Investigator
      INOKUCHI Tsugio
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nagasaki University.
  •  原核生物HSP90分子シャペロンの機能は真核生物と同じか?Principal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  Regulation of pathologic root resorption by control of MAPK signaling

    • Principal Investigator
      HOTOKEZAKA Hitoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Nagasaki University
  •  原核生物および真核生物HSP90分子シャペロン共通の作用メカニズムPrincipal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  Comprehensive approach to identify novel molecules involved in osteogenesis and chondrogenesis during tooth development.

    • Principal Investigator
      TSUKAZAKI Tomoo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  FUNCTIONAL ANALYSIS OF HEAT SHOCK PROTEIN HtpG FROM PF gingivalis WHICH CAUSES PERIODONTITIS

    • Principal Investigator
      KOBAYAKAWA Takeshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Collagen processing and molecular chaperones : molecular anatomy based on the domain structuresPrincipal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  The effect of stress proteins that induce proinflammatory cytokines on pathological root resorption.

    • Principal Investigator
      HOTOKEZAKA Hitoshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Nagasaki University
  •  HSP90ファミリータンパク質の基本構造とターゲット分子選択機構Principal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagasaki University
  •  ストレスタンパク質HSP90の構造と自己免疫原性の解析Principal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Iwate Medical University
  •  Domain structure, expressional regulation and autoimmunity of HSP90Principal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
      Iwate Medical University
  •  レチノイン酸によるヒト口腔癌細胞株の増殖、分化の遺伝子転写制御機構

    • Principal Investigator
      KYAKUMOTO Seiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Iwate Medical University
  •  Autocrine growth signal in human salivary gland adenocarcinoma cell line.

    • Principal Investigator
      OTA Minoru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Iwate Medical University
  •  Analysis of the androgen response element of mouse EGF gene by use of the androgen receptor expressed in Echerichia coliPrincipal Investigator

    • Principal Investigator
      NEMOTO Takayuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Iwate Medical University
  •  熱ショックタンパク質の構造とステロイドレセプター系における作用機構の解析Principal Investigator

    • Principal Investigator
      根本 孝幸
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Iwate Medical University
  •  Analysis of Production of Epidermal Growth Factor in Submandibular Gland Controled by Hormons

    • Principal Investigator
      OHARA Yuko
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Iwate Medical University
  •  STUDIES ON MECHANISM OF AUTOCRINE GROWTH OF A HUMAN SALIVARY GLAND ADENOCARCINOMA BY EPIDERMAL GROWTH FACTOR

    • Principal Investigator
      OTA Minoru
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      IWATA MEDICAL UNIVERSITY
  •  Mechanism of gene expression by androgen receptor in rat and mouse submandibular glands

    • Principal Investigator
      OTA Minoru
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Iwate Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Endocarditis2012

    • Author(s)
      Ohara-Nemoto Yuko
    • Publisher
      INTECK
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Book] Pathogenesis and Treatment of Periodontitis2012

    • Author(s)
      Kimura, S., Ohara-Nemoto, Y., Shimoyama, Y., Ishikawa, T., Sasaki, M.
    • Total Pages
      16
    • Publisher
      Pathogenic factors of P. gingivalis and the host defence mechanisms
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Book] NVS and staphylococci in the oral cavity, a cause of infective endocarditis2012

    • Author(s)
      Ohara-Nemoto, Y., Kimura, S., Nemoto, T.K.
    • Publisher
      In Endocarditis InTech
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Book] Endocarditis2012

    • Author(s)
      Ohara-Nemoto, Y., Kimura, S., Nemoto, T.K.
    • Total Pages
      22
    • Publisher
      NVS and staphylococci in the oral cavity, a cause of infective endocarditis
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Book] Pathogenic factors of P. Gingivalis and the host defence mechanismsn Pathogenesis and Treatment of Periodontitis.2012

    • Author(s)
      Kimura, S., Ohara-Nemoto, Y., Shimoyama, Y., Ishikawa, T., Sasaki, M.
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Book] InTech Endocarditis ISBN 978-953-307-901-1 Edited by: Francisco Ramón Breijo-Márquez2012

    • Author(s)
      Ohara-Nemoto Y, Kimura S, and Nemoto TK
    • Total Pages
      10
    • Publisher
      NVS and Staphylococci in the oral cavity – a case of infective endodontalis
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Journal Article] Potential elevation of exopeptidase activity of Glu-specific endopeptidase I/GluV8 mediated by hydrophobic P1'-position amino acid residue2024

    • Author(s)
      Nemoto TK, Nishimata H, Shirakura K, Ohara-Nemoto Y.
    • Journal Title

      Biochimie

      Volume: 220 Pages: 99-106

    • DOI

      10.1016/j.biochi.2023.12.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K09125, KAKENHI-PROJECT-23K09461, KAKENHI-PROJECT-19K19273
  • [Journal Article] Immunoelectron Microscopic Analysis of Dipeptidyl-Peptidases and Dipeptide Transporter Involved in Nutrient Acquisition in Porphyromonas gingivalis2023

    • Author(s)
      Shimoyama Yu、Sasaki Daisuke、Ohara-Nemoto Yuko、Nemoto Takayuki K.、Nakasato Manami、Sasaki Minoru、Ishikawa Taichi
    • Journal Title

      Current Microbiology

      Volume: 80 Issue: 4 Pages: 106-106

    • DOI

      10.1007/s00284-023-03212-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17045, KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071, KAKENHI-PROJECT-23K09125
  • [Journal Article] Exacerbation mechanism of type 2 diabetes mellitus by periodontopathic bacterial dipeptidyl-peptidases (DPPs)2023

    • Author(s)
      Nakasato-Suzuki Manami、Shimoyama Yu、Ohara-Nemoto Yuko、Sasaki Daisuke、Nemoto Takayuki K.、Yaegashi Takashi
    • Journal Title

      Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)

      Volume: 65 Issue: 1 Pages: 1-8

    • DOI

      10.2329/perio.65.1

    • ISSN
      0385-0110, 1880-408X
    • Year and Date
      2023-03-31
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17045, KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071
  • [Journal Article] Expanded substrate specificity supported by P1′ and P2′ residues enables bacterial dipeptidyl-peptidase 7 to degrade bioactive peptides2022

    • Author(s)
      Ohara-Nemoto Yuko、Shimoyama Yu、Ono Toshio、Sarwar Mohammad Tanvir、Nakasato Manami、Sasaki Minoru、Nemoto Takayuki K.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 3 Pages: 101585-101585

    • DOI

      10.1016/j.jbc.2022.101585

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19005, KAKENHI-PROJECT-19K10071, KAKENHI-PROJECT-19K10045
  • [Journal Article] Dipeptidyl-peptidases: Key enzymes producing entry forms of extracellular proteins in asaccharolytic periodontopathic bacterium Porphyromonas gingivalis2021

    • Author(s)
      Nemoto TK, Ohara Nemoto Y.
    • Journal Title

      Mol Oral Microbiol

      Volume: 36 Issue: 2 Pages: 145-156

    • DOI

      10.1111/omi.12317

    • NAID

      120006988506

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071
  • [Journal Article] Characterization of substrate specificity and novel autoprocessing mechanism of dipeptidase A from Prevotella intermedia2020

    • Author(s)
      Sarwar, M.T., Ohara-Nemoto, Y., Kobayakawa, T., Naito, M., Nemoto, T.K.
    • Journal Title

      Biol. Chem.

      Volume: 401 Issue: 5 Pages: 629-642

    • DOI

      10.1515/hsz-2019-0387

    • NAID

      120006988332

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10071, KAKENHI-PROJECT-19K10045
  • [Journal Article] Preferential dipeptide incorporation of Porphyromonas gingivalis mediated by proton-dependent oligopeptide transporter (Pot)2020

    • Author(s)
      Ohara-Nemoto Y, Sarwar MT, Shimoyama Y, Kobayakawa T, Nemoto TK.
    • Journal Title

      FEMS Microbial Lett

      Volume: 367 Issue: 24 Pages: 1-8

    • DOI

      10.1093/femsle/fnaa204

    • NAID

      120006980746

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071, KAKENHI-PROJECT-18K09557
  • [Journal Article] Characterization of bacterial acylpeptidyl-oligopeptidase.2019

    • Author(s)
      Nemoto TK, Ono T, Kobayakawa T, Ohara-Nemoto Y.
    • Journal Title

      Biochimie

      Volume: 163 Pages: 50-57

    • DOI

      10.1016/j.biochi.2019.05.007

    • NAID

      120006987741

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071
  • [Journal Article] Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor.2019

    • Author(s)
      Baba TT, Miyazaki T, Ohara-Nemoto Y, Nemoto TK.
    • Journal Title

      Cell Biochem Funct

      Volume: 37 Issue: 6 Pages: 400-407

    • DOI

      10.1002/cbf.3418

    • NAID

      120006988454

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10045, KAKENHI-PROJECT-19K10071
  • [Journal Article] Establishment of potent and specific synthetic substrate for dipeptidyl-peptidase 7.2018

    • Author(s)
      Nemoto TK, Ono T, Ohara-Nemoto Y.
    • Journal Title

      Anal Biochem

      Volume: 548 Pages: 78-81

    • DOI

      10.1016/j.ab.2018.02.008

    • NAID

      120006987355

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11047, KAKENHI-PROJECT-16K11481
  • [Journal Article] Distribution of dipeptidyl peptidase (DPP) 4, DPP5, DPP7, and DPP11 in human oral microbiota ? potent biomarkers indicating presence of periodontopathic bacteria2018

    • Author(s)
      Ohara-Nemoto Yuko、Shimoyama Yu、Nakasato Manami、Nishimata Haruka、Ishikawa Taichi、Sasaki Minoru、Kimura Shigenobu、Nemoto Takayuki K
    • Journal Title

      FEMS Microbiology Letters

      Volume: 365 Pages: 1-7

    • DOI

      10.1093/femsle/fny221

    • NAID

      120006987966

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K12036, KAKENHI-PROJECT-18K09557, KAKENHI-PROJECT-17K17286, KAKENHI-PROJECT-17K17336, KAKENHI-PROJECT-16K11481
  • [Journal Article] Identification of a new subtype of dipeptidyl peptidase 11 and a third group of the S46-family members specifically present in the genus Bacteroides.2018

    • Author(s)
      Nemoto TK, Bezerra GA, Ono T, Nishimata H, Fujiwara T, Ohara-Nemoto Y.
    • Journal Title

      Biochimie

      Volume: 147 Pages: 25-35

    • DOI

      10.1016/j.biochi.2017.10.015

    • NAID

      120006987398

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11047, KAKENHI-PROJECT-17K17336, KAKENHI-PROJECT-16K11481
  • [Journal Article] Periodontopathic bacterial DPP4 as a risk factor for type 2 diabetes mellitus2018

    • Author(s)
      中里 茉那美,下山 佑,根本 優子,佐々木 大輔,根本 孝幸,佐々木 実,八重柏 隆
    • Journal Title

      Dental Journal of Iwate Medical University

      Volume: 43 Issue: 1 Pages: 48-60

    • DOI

      10.20663/iwateshigakukaishi.43.1_48

    • NAID

      130007396589

    • ISSN
      0385-1311, 2424-1822
    • Year and Date
      2018-05-25
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Journal Article] Dominant prevalence of Porphyromonas gingivalis fimA types I and IV in healthy Japanese children.2017

    • Author(s)
      Shimoyama Y, Ohara-Nemoto Y, Kimura M, Tanaka M, Kimura S, and Nemoto TK.
    • Journal Title

      J Dent Sci.

      Volume: 印刷中 Issue: 3 Pages: 213-219

    • DOI

      10.1016/j.jds.2017.03.006

    • NAID

      120006987517

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11047, KAKENHI-PROJECT-16K11481
  • [Journal Article] Bacterial protease uses distinct thermodynamic signatures for substrate recognition.2017

    • Author(s)
      Bezerra, G. A., Ohara-Nemoto, Y., Fedosyuk, S., Cornaciu, I., Hoffmann, G., Round, A., Marquez, J. A., Nemoto, T.K., Djinovic-Carugo, K.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 2848-2848

    • DOI

      10.1038/s41598-017-03220-y

    • NAID

      120006987515

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11481, KAKENHI-PROJECT-15K11047
  • [Journal Article] Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4.2017

    • Author(s)
      Ohara-Nemoto, Y., Nakasato, M., Shimoyama, Y., Baba, T., Kobayakawa, T., Ono, T., Yaegashi, T., Kimura, S., Nemoto, T.K.
    • Journal Title

      Infection and Immunity

      Volume: 85 Issue: 9

    • DOI

      10.1128/iai.00277-17

    • NAID

      120006987494

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11481, KAKENHI-PROJECT-15K11020, KAKENHI-PROJECT-15K11047
  • [Journal Article] A Porphyromonas gingivalis periplasmic novel exopeptidase, acylpeptidyl oligopeptidase, releases N-acylated di- and tri-peptides from oligopeptides.2016

    • Author(s)
      Nemoto, T.K., Ohara-Nemoto, Y., Bezerra, G. A., Shimoyama, Y. and Kimura, S.
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Issue: 11 Pages: 5913-5925

    • DOI

      10.1074/jbc.m115.687566

    • NAID

      120006986807

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11020, KAKENHI-PROJECT-15K11047
  • [Journal Article] Skp2 regulates the expression of MMP-2 and MMP-9, and enhances the invasion potential of oral squamous cell carcinoma.2016

    • Author(s)
      Yamada SI, Yanamoto S, Naruse T, Matsushita Y, Takahashi H, Umeda M, Nemoto TK, and Kurita H.
    • Journal Title

      Pathol Oncol Res.

      Volume: 52 Issue: 3 Pages: 22-29

    • DOI

      10.1007/s12253-016-0049-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Journal Article] Porphyromonas gingivalis exopeptidases as crucial factors for its amino acid metabolism2016

    • Author(s)
      Nemoto, T.K., Ohara-Nemoto, Y.
    • Journal Title

      Jap. Dent. Sci. Rev.

      Volume: 52 Issue: 1 Pages: 22-29

    • DOI

      10.1016/j.jdsr.2015.08.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462894, KAKENHI-PROJECT-15K11047
  • [Journal Article] Skp2 regulates the expression of MMP-2 and MMP-9, and enhances the invasion potential of oral squamous cell carcinoma.2016

    • Author(s)
      Yamada, SI, Yanamoto S, Naruse T, Matsushita Y, Takahashi H, Umeda M, Nemoto TK, and Kurita H.
    • Journal Title

      Pathol Oncol Res.

      Volume: 52

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Journal Article] Identification and characterization of prokaryotic dipeptidyl-peptidase 5 from Porphyromonas gingivalis.2014

    • Author(s)
      Ohara-Nemoto Y, Rouf SMA, Naito M, Yanase A, Tetsuo F, Ono T, Kobayakawa T, Shimoyama Y, Kimura S, Nakayama K, Saiki K, Konishi K, Nemoto TK.
    • Journal Title

      J. Biol. Chem.

      Volume: 289 Issue: 9 Pages: 5438-5448

    • DOI

      10.1074/jbc.m113.527333

    • NAID

      120006986777

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592809, KAKENHI-PROJECT-25293375, KAKENHI-PROJECT-25462893, KAKENHI-PROJECT-25462894, KAKENHI-PROJECT-24592775
  • [Journal Article] A bone substitute with high affinity for vitamin D binding protein-relationship to niche of osteoclasts2014

    • Author(s)
      Ikeda, T., Kasai, M., Tatsukawa, E., Kamitakahara, M., Shibata, Y., Yokoi, T., Nemoto, T. K., Ioku, K.
    • Journal Title

      J. Cell Mol. Med

      Volume: 18 Issue: 1 Pages: 170-180

    • DOI

      10.1111/jcmm.12180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22390343, KAKENHI-PROJECT-23659246, KAKENHI-PROJECT-24592809
  • [Journal Article] 新規ジペプチジルペプチダーゼと歯周病原性細菌のタンパク質分解・ 取り込み機構の解明2014

    • Author(s)
      根本孝幸
    • Journal Title

      発酵研究所助成研究報告集 IFO Research Communications

      Volume: 28 Pages: 21-21

    • Data Source
      KAKENHI-PROJECT-24592809
  • [Journal Article] Identification of dipeptidyl-peptidase (DPP)5 and DPP7 in Porphyromonas endodontalis, distinct from those in Porphyromonas gingivalis.2014

    • Author(s)
      Nishimata H, Ohara-Nemoto Y, Baba TT, Hoshino T, Fujiwara T, Shimoyama Y, Kimura S, Nemoto TK.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 12 Pages: 1-15

    • DOI

      10.1371/journal.pone.0114221

    • NAID

      120006986295

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592809, KAKENHI-PROJECT-25462894, KAKENHI-PROJECT-24592775
  • [Journal Article] Co-overexpression of cortactin and CRKII increases migration and invasive potential in oral squamous cell carcinoma2014

    • Author(s)
      Yamada S, Yanamoto S, Rokutannda S, Miyakoshi M, Naruse T, Kawakita A, Kawasaki G, Nemoto TK, Umeda M
    • Journal Title

      J Oral Maxillofac Surg Med Pathol

      Volume: 26 Issue: 1 Pages: 14-21

    • DOI

      10.1016/j.ajoms.2012.11.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Journal Article] In vitro processing of glutamyl endopeptidase proenzymes from Enterococcus faecalis and importance of N-terminal residue in enzyme catalysis.2013

    • Author(s)
      Rouf, S. M., Ohara-Nemoto, Y., Ono, T., Shimoyama, Y., Kimura, S. and Nemoto, T. K.
    • Journal Title

      Adv. Biochem.

      Volume: 1 Issue: 5 Pages: 73-80

    • DOI

      10.11648/j.ab.20130105.11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592775, KAKENHI-PROJECT-25462894
  • [Journal Article] Discrimination based on Gly and Arg/Ser at Position 673 between Dipeptidyl-peptidase (DPP) 7 and DPP11, Widely Distributed DPPs in Pathogenic and Environmental Gram-Negative Bacteria2013

    • Author(s)
      Rouf, S.M.A., Ohara-Nemoto, Y., Hoshino, T., Fujiwara, T., Ono, T., Nemoto, T.K.
    • Journal Title

      Biochimie

      Volume: 95 Issue: 4 Pages: 824-831

    • DOI

      10.1016/j.biochi.2012.11.019

    • NAID

      120006985514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592070, KAKENHI-PROJECT-24592809
  • [Journal Article] In vitro measurement of protease activity of exfoliative toxin A using synthetic peptide substrates2013

    • Author(s)
      Tachi, M.T., Ohara-Nemoto, Y., Baba, T.T., Kobayakawa, T., Fujita, S., Ikeda, T., Ayuse, T., Oi, K., Nemoto, T.K.
    • Journal Title

      Acta Medica Nagasakiensia

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Journal Article] Measurement of protease activity of exfoliative toxin A using synthetic peptidyl substrates and correlation between in vivo and in vitro activities.2013

    • Author(s)
      Tachi, M. T., Ohara-Nemoto, Y., Baba, T.T., Kobayakawa, T., Fujita, S., Ikeda, T., Ayuse, T., Oi, K., Nemoto, T.K.
    • Journal Title

      Acta Med. Nagasaki.

      Volume: 58 Pages: 41-48

    • NAID

      110009614178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Journal Article] Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin2013

    • Author(s)
      Baba TT, Ohara-Nemoto Y, Miyazaki T, and Nemoto TK
    • Journal Title

      Cell Biochem Funct.

      Volume: 28 Issue: 8 Pages: 652-659

    • DOI

      10.1002/cbf.2951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592809, KAKENHI-PROJECT-25462894
  • [Journal Article] Phenylalanine 664 of dipeptidyl peptidase (DPP) 7 and Phenylalanine 671 of DPP11 mediate preference for P2-position hydrophobic residues of a substrate.2013

    • Author(s)
      Rouf, S. M., Ohara-Nemoto, Y., Ono, T., Shimoyama, Y., Kimura, S. and Nemoto, T. K.
    • Journal Title

      FEBS Open Bio.

      Volume: 3 Issue: 1 Pages: 177-183

    • DOI

      10.1016/j.fob.2013.03.004

    • NAID

      120006985739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592775, KAKENHI-PROJECT-24592809, KAKENHI-PROJECT-25462894
  • [Journal Article] Propeptide processing and the proteolytic activity of proenzymes of the staphylococcal and enterococcal GluV8-family protease2012

    • Author(s)
      Rouf SMA, Ohara-Nemoto Y, Shimoyama Y, Kimura S, Ono T and Nemoto TK
    • Journal Title

      Indian J. Biochem. Biophys.

      Volume: 48 Pages: 421-427

    • NAID

      120006985515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Journal Article] Asp-and Glu-specific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis that ensures utilization of proteinaceous energy sources2011

    • Author(s)
      Ohara-Nemoto Y, Shimoyama Y, Kimura Y, Kon A, Haraga H, Ono T, and Nemoto TK
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 38115-38127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Overexpression of CRKII increases migration and invasive potential in oral squamous cell carcinoma2011

    • Author(s)
      Yamada S, Yanamoto S, Kawasaki G, Rokutanda S, Yonezawa H, Kawakita A, and Nemoto TK
    • Journal Title

      Cancer Lett

      Volume: 303 Pages: 84-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Asp- and Glu-specific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis that ensures utilization of proteinaceous energy sources2011

    • Author(s)
      Ohara-Nemoto Y, Shimoyama Y, Kimura S, Kon A, Haraga H, Nemoto TK
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 44 Pages: 38115-38127

    • DOI

      10.1074/jbc.m111.278572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367, KAKENHI-PROJECT-22592070
  • [Journal Article] Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma2010

    • Author(s)
      Yamada S, Yanamoto S, Kawasaki G, Mizuno A and Nemoto TK
    • Journal Title

      Pathol. Oncol. Res

      Volume: 16(4) Pages: 523-531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] RNAi-mediated down-regulation of α-actinin-4 decreases invasion potential in oral squamous cell carcinoma.2010

    • Author(s)
      Yamada, S., Yanamoto, S., Yoshida, H., Yoshitomi, I., Kawasaki, G., Mizuno A., Nemoto, T.K.
    • Journal Title

      Int J Oral Maxillofac Surg. 39(1)

      Pages: 61-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma.2010

    • Author(s)
      Yamada S, Yanamoto S, Kawasaki G, Mizuno A, Nemoto TK.
    • Journal Title

      Pathol Oncol Res. (in press.)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Amino acid residues modulating the activities of staphylococcal glutamyl endopeptidases2010

    • Author(s)
      Ono, T., Ohara-Nemoto, Y., Shimoyama, Y., Okawara, H., Kobayakawa, T., Baba, T., Kimura, S., Nemoto, T.K.
    • Journal Title

      Biol Chem

      Volume: 391 Issue: 10 Pages: 1221-1232

    • DOI

      10.1515/bc.2010.116

    • NAID

      120006984895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Journal Article] Amino acid residues modulating the activities of staphylococcal glutamyl endopeptidases2010

    • Author(s)
      Ono T, Ohara-Nemoto Y, Shimoyama Y, Okawara H, Kobayakawa T, Baba TT, Kimura S, and Nemoto TK
    • Journal Title

      Biol. Chem

      Volume: 391 Pages: 1221-1232

    • NAID

      120006984895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] RNAi-mediated down-regulation ofτ-actinin-4 decreases invasion potential in oral 4 squamous cell carcinoma2010

    • Author(s)
      Yamada S, Yanamoto S, Yoshida H, Yoshitomi I, Kawasaki G, Mizuno A and Nemoto TK
    • Journal Title

      Int. J. Oral. Maxillofac. Surg

      Volume: 39(1) Pages: 61-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] 幼若マウスにおける実験的水疱性膿痂疹作成と表皮剥奪毒素による角化細胞障害の顕微鏡的観察2009

    • Author(s)
      永海多恵, 根本優子, 広田剛, 石崎美智子, 多田讓治
    • Journal Title

      化学療法の領域

      Volume: 25(8) Pages: 109-116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Single nucleotide polymorphism that accompanies a missense mutation(Gln488His) impedes the dimerization of Hsp902009

    • Author(s)
      Kobayakawa T, Yamada S, Mizuno A, Ohara-Nemoto Y, Nemoto TK
    • Journal Title

      Protein J

      Volume: 28(1) Pages: 24-28

    • NAID

      120006983318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Effects of fosfomycin on Shiga toxin-producing Escherichia coli : quantification of copy numbers of Shiga toxin genes and their expression levels using real-time PCR.2009

    • Author(s)
      Ichinohe N, Ohara-Nemoto Y, Nemoto TK, Kimura S, Ichinohe S.
    • Journal Title

      J.Med.Microbiol. 58

      Pages: 971-973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] The relationship of the salivary quantitative levels of Streptococcus mutans and S. sobrinus in mothers to the caries status and the colonization in plaque of mutans streptococci in their 2. 5-year-old children.2009

    • Author(s)
      Kishi M, Abe A, Kishi K, Ohara-Nemoto, Y, Kimura S, Yonemitsu M
    • Journal Title

      Comm Dent Oral Epidemiol

      Volume: 37(3) Pages: 241-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Single nucleotide polymorphism that accompanies a missense mutation(Gln488His)impedes the dimerization of Hsp90.2009

    • Author(s)
      Kobayakawa T, Yamada S, Mizuno A, Ohara-Nemoto Y, Baba TT, Nemoto TK
    • Journal Title

      Protein J. 28

      Pages: 24-28

    • NAID

      120006983318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Influences of fosfomycin on Shiga toxin gene expression from Shiga toxin-producing Escherichia coli2009

    • Author(s)
      Ichinohe N, Ohara-Nemoto Y, Nemoto TK, Kimura S, Ichinohe S
    • Journal Title

      J Med Microbiol

      Volume: 58(7) Pages: 971-973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Determination of three amino acids that caused the alteration of proteolytic activities of staphylococcal glutamyl endopeptidases.2009

    • Author(s)
      Nemoto TK, Ono T, Shimoyama Y, Kimura S, Ohara-Nemoto Y
    • Journal Title

      Biol.Chem. 390

      Pages: 277-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Determination of three amino acids that caused the alteration of proteolytic activities of staphylococcal glutamyl endopeptidases2009

    • Author(s)
      Nemoto TK, Ono T, Shimoyama Y, Kimura S, Ohara-Nemoto Y
    • Journal Title

      Biol Chem

      Volume: 390(3) Pages: 277-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Journal Article] Occurrence of staphylococci in oral cavities of healthy adults and nasal-oral trafficking of the bacteria2008

    • Author(s)
      Ohara-Nemoto, Y, Haraga, H, Kimura, S, Nemoto, TK
    • Journal Title

      J. Med. Microbiol 57

      Pages: 95-99

    • NAID

      120006982334

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Homologous and heterologous expression and maturation processing of extracellular glutamyl endopeptidase of Staphylococcus epidermiths2008

    • Author(s)
      Ohara-Nemoto, Y, Ono, T, Shimoyama, Y, Kimura, S, Nemoto, TK
    • Journal Title

      Biol. Chem (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Homologous and heterologous expression and maturation processing of extracellular glutamyl endopeptidase of Staphylococcus epidermidis2008

    • Author(s)
      Ohara-Nemoto Y, Ono T., Shimoyama Y., Kimura S., Nemoto TK
    • Journal Title

      Biol.Chem. (in press)

    • NAID

      120006982370

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Occurrence of staphylococci in oral cavities of healthy adults and nasal-oral trafficking of the bacteria2008

    • Author(s)
      Ohara-Nemoto Y., Haraga H., Kimura S.and Nemoto T.K
    • Journal Title

      J.Med.Microbiol.57, 95-99(2008) 57

      Pages: 95-99

    • NAID

      120006982334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli2008

    • Author(s)
      Nemoto TK, Ohara-Nemoto Y, Ono T, Kobayakawa T, Shimoyama Y(他2名)
    • Journal Title

      FEBS J. 275

      Pages: 573-587

    • NAID

      120006982394

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli2008

    • Author(s)
      Nemoto, TK, Ohara-Nemoto, Y, Ono, T, Kobayakawa, T, Shimoyama, Y, Kimura, S, Takagi, T
    • Journal Title

      FEBS J 275

      Pages: 5723-587

    • NAID

      120006982394

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Substitution of only two residues of human Hsp90α causes impeded dimerization of Hsp90β2008

    • Author(s)
      Kobayakawa T., Yamada S., Mizuno A.and Nemoto T.K.
    • Journal Title

      Cell Stress and Chaperones (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Occurrence of staphylococci in oral cavities of healthy adults and nasal-oral traffickins of the bacteria2008

    • Author(s)
      Ohara-Nemoto Y, Haraga H, Kimura S, Nemoto TK
    • Journal Title

      J.Med.Microbiol.57, 95-99(2008) 57

      Pages: 95-99

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Substitution of only two residues of human Hsp90α causes impeded dimerization of Hsp90β2008

    • Author(s)
      Kobayakawa T, Yamada S, Mizuno A, Nemoto T.K.
    • Journal Title

      Cell Stress and Chaperones 13(1)

      Pages: 97-104

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Substitution of only two residues of human Hsp90α causes impeded dimerization of Hsp90β2008

    • Author(s)
      Kobayakawa, T, Yamada, S, Mizuno, A, Nemoto, TK
    • Journal Title

      Cell Stress Chaper 13, (1)

      Pages: 97-104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli2008

    • Author(s)
      Nemoto T.K., Ohara-Nemoto Y., Ono T., Kobayakawa T., Shimoyama Y., (他2名)
    • Journal Title

      FEBS J.275, 5723-587(2008) 275

      Pages: 573-587

    • NAID

      120006982394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] A novel in vitro pharmacokinetic/pharmacodynamic model based on two-compartment open model used to simulate serum drug concentration-time profiles2007

    • Author(s)
      Tomita, T, Ohara-Nemoto, Y, Moriyama, H, Ozawa, A, Takeda, Y, Kikuchi, K
    • Journal Title

      Microbiol. Immunol 51

      Pages: 567-575

    • NAID

      10020280446

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] A disulfide bridge mediated at cysteine 574 is formed in the dimer of the 70-kDa heat shock protein.2007

    • Author(s)
      Nemoto, T.K., Fukuma, Y., Itoh, H., Takashi, T., Ono T
    • Journal Title

      Journal of Biochemistry 139(4)

      Pages: 677-687

    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] A novel in vitro pharmacokinetic/pharmacodynamic model based on two-compartment open model used to simulate serum drug concentration-time profiles2007

    • Author(s)
      Tomita T, Ohara-Nemoto Y, Moriyama H, Ozawa A, Takeda Y, Kikuchi K.
    • Journal Title

      Microbiol.Immunol. 51(5)

      Pages: 567-575

    • NAID

      10020280446

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] A novel in vitro pharmacokinetic/pharmacodynamic model based on two-compartment open model used to simulate serum drug concentration-time profiles2007

    • Author(s)
      Tomita, T., Ohara-Nemoto, Y., Moriyama, H., Ozawa, A., Takeda, Y., Kikuchi, K.
    • Journal Title

      Microbiol.Immunol 51(5)

      Pages: 567-575

    • NAID

      10020280446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Journal Article] The region, adjacent to the highly immunogenic site and shielded by the middle domain, is responsible for self-oligomerization/client binding of HSP90 molecular Chaperon2004

    • Author(s)
      Nemoto T.K., Fukuma Y., Yamada S., 他4名
    • Journal Title

      Biochemistry 43

      Pages: 7628-7636

    • Data Source
      KAKENHI-PROJECT-15032243
  • [Journal Article] In vitro measurement of protease activity of exfoliative toxin A using synthetic peptide substrates.

    • Author(s)
      Tachi, M.T., Ohara-Nemoto, Y., Baba, T.T., Kobayakawa, T., Fujita, S., Ikeda, T., Ayuse, T., Oi, K., Nemoto, T.K.
    • Journal Title

      Acta Medica Nagasakiensia

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Patent] 組換えプロテアーゼの製造方法2007

    • Inventor(s)
      根本 孝幸, 根本 優子
    • Industrial Property Rights Holder
      長崎大学
    • Industrial Property Number
      2007-077746
    • Filing Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Localization of DPPs and dipeptide transporter Pot in Porphyromonas gingivalis defined by IEM.2021

    • Author(s)
      下山佑,根本優子,根本孝幸,石河太知,佐々木大輔,古玉芳豊,木村重信,佐々木実
    • Organizer
      第94回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10071
  • [Presentation] Localization of DPPs and dipeptide transporter Pot in Porphyromonas gingivalis defined by IEM.2020

    • Author(s)
      Yu Shimoyama, Yuko Ohara-Nemoto, Takayuki K. Nemoto, Taichi Ishikawa, Daisuke Sasaki, Yoshitoyo Kodama, Shigenobu Kimura and Minoru Sasaki
    • Organizer
      第94回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10071
  • [Presentation] Prevotella intermediaのジペプチダーゼの同定: C69.001ファミリージペプチダーゼAのN末特異性の再定義2019

    • Author(s)
      1.Tanvir S.M.,根本優子,小野俊雄,根本孝幸
    • Organizer
      第61回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10071
  • [Presentation] Proton-coupled dipeptide transporter in Porphyromonas gingivalis2019

    • Author(s)
      根本優子,Tanvir SM, 小早川健,根本孝幸
    • Organizer
      第61回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10071
  • [Presentation] 歯周病細菌Prevotella intermedia のジペプチダーゼの同定: C69.001 ファミリージペプチダーゼAのN 末特異性の再定義2019

    • Author(s)
      Sarwar Mohammad Tanvir,根本優子,小野俊雄,根本孝幸
    • Organizer
      第61回歯科基礎医学会学術大会・総会
    • Data Source
      KAKENHI-PROJECT-19K10045
  • [Presentation] Porphyromonas gingivalisのH+依存性ジペプチドトランスポーター2019

    • Author(s)
      根本優子,Sarwar Tanvir,小早川健,根本孝幸
    • Organizer
      第61回歯科基礎医学会学術大会・総会
    • Data Source
      KAKENHI-PROJECT-19K10045
  • [Presentation] S46 family dipeptidyl peptidases (DPPs) in the genus Bacteroides2017

    • Author(s)
      根本優子,小野俊雄,根本孝幸
    • Organizer
      第90回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Bacteroides 属菌が有する S46 ファミリージペプチジ ルペプチダーゼ2017

    • Author(s)
      根本 優子, 小野 俊雄, 根本 孝幸
    • Organizer
      第90回日本細菌学会
    • Place of Presentation
      仙台国際センター (宮城県仙台市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Porphyromonas gingivalis および Tannerella forsythia のジペプチジルペプチダーゼ4 活性とインクレチン分解能2017

    • Author(s)
      2.中里茉那美,根本優子,下山佑,木村重信,佐々木大輔,伊東俊太郎,佐々木実,八重柏隆
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] 歯周病原性細菌アシルペプチジルオリゴペプチダーゼ(AOP)のアシルペプチド選択機構.(Acylpeptide recognition mechanism of acylpeptidyl oligopeptidase in periodontopathic bacteria)2017

    • Author(s)
      根本孝幸,小野俊雄,根本優子
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] 歯周病原性細菌アシルペプチジルオリゴペプチダーゼ(AOP)のアシルペプチド選択機構2017

    • Author(s)
      根本孝幸,小野俊雄,根本優子
    • Organizer
      第59回歯科基礎医学会学術大会・総会
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Porphyromonas gingivalis および Tannerella forsythia のジペプチジルペプチダーゼ4 活性とインクレチン分解能2017

    • Author(s)
      中里茉那美,根本優子,下山佑,木村重信,佐々木大輔,伊東俊太郎,佐々木実,八重柏隆
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Bacteroides属菌が有するS46ファミリージペプチジルペプチダーゼ2017

    • Author(s)
      根本優子,小野俊雄,根本孝幸
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Bacteroides属菌が有するS46ファミリージペプチジルペプチダーゼ. (S46 family dipeptidyl peptidases (DPPs) in the genus Bacteroides)2017

    • Author(s)
      根本優子,小野俊雄,根本孝幸
    • Organizer
      第90回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Degradation of incretin by the prokaryotic dipeptidyl-peptidase 4 from Porphyromonas gingivalis.2016

    • Author(s)
      Shimoyama, Y., Ohara-Nemoto, Y., Nemoto, T.K., Nakasato, M., Yaegashi, T., Ishikawa, T., Sasaki, M., Kimura, S.
    • Organizer
      Microbe 2016
    • Place of Presentation
      ホ゛ストン(米国)
    • Year and Date
      2016-06-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Degradation of incretin by the prokaryotic dipeptidyl-peptidase 4 from Porphyromonas gingivalis.2016

    • Author(s)
      Shimoyama Y, Ohara-Nemoto Y, Nemoto TK, Nakasato M, Yaegashi T, Ishikawa T, Sasaki M, Kimura S
    • Organizer
      ASM 2016 General meeting
    • Place of Presentation
      ボストン (アメリカ)
    • Year and Date
      2016-06-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Porphyromonas sp. dipeptidyl peptidases 11 distinguish substrates from end products via distinct thermodynamic signatures.2016

    • Author(s)
      Bezerra, G. A., Ohara-Nemoto, Y., Fedosyuk, S., Cornaciu, I., Hoffmann, G., Marquez, J. A., Nemoto, T.K., Djinovic-Carugo, K.
    • Organizer
      EMBO Conference The biochemistry and chemistry of biocatalysis: From understanding to design
    • Place of Presentation
      オウル(フィンランド)
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Characterization of dipeptidyl-peptidase 4 from Tannerella forsythia.2016

    • Author(s)
      Nakasato, M., Shimoyama, Y., Ohara-Nemoto, Y., Nemoto, T.K., Takahashi, S., Ito, S., Sasaki, D., Yaegashi, T., Kimura, S.
    • Organizer
      Microbe 2016
    • Place of Presentation
      ホ゛ストン(米国)
    • Year and Date
      2016-06-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Porphyromonas gingivalisのアミノ酸及びオリゴペプチド輸送系の解析2016

    • Author(s)
      根本優子,小早川健,馬場友巳,根本孝幸
    • Organizer
      第58回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2016-08-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11481
  • [Presentation] Porphyromonas gingivalisのアミノ酸及びオリゴペプチド輸送系の解析 (Amino acid and oligopeptide transporters in Porphyromonas gingivalis)2016

    • Author(s)
      根本優子,小早川健,馬場友巳,根本孝幸
    • Organizer
      第58回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Djinovic-Carugo K: Porphyromonas sp. dipeptidyl peptidases 11 distinguish substrates from end products via distinct thermodynamic signatures.2016

    • Author(s)
      Bezerra GA, Ohara-Nemoto Y, Fedosyuk S, Cornaciu I, Hoffmann G, Marquez JA, Nemoto TK,
    • Organizer
      EMBO Conference The biochemistry and chemistry of biocatalysis: From understanding to design
    • Place of Presentation
      オウル (フィンランド)
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Characterization of dipeptidyl-peptidase 4 from Tannerella forsythia.2016

    • Author(s)
      Nakasato M, Shimoyama Y, Ohara-Nemoto Y, Nemoto TK, Takahashi S, Ito S, Sasaki D, Yaegashi T, Kimura S
    • Organizer
      ASM 2016 General meeting
    • Place of Presentation
      ボストン (アメリカ)
    • Year and Date
      2016-06-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] 小児プラークにおけるミュータンスレンサ球菌定着量と齲蝕罹患率の関連 (Quantification of mutans streptococci in children’s plaques and its relationship to the caries prevalence).2016

    • Author(s)
      蒔苗 剛, 下山 佑, 田中光郎,石河太知, 古玉芳豊, 佐々木 実, 根本優子, 根本孝幸, 木村重信
    • Organizer
      第58回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] 非RI蛍光試薬によるPorphyromonas gingivalisのアミノ酸とジペプチドの取り込みの評価2015

    • Author(s)
      小早川健,根本優子,馬場友巳,根本孝幸
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      朱鷺メッセ( 新潟市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Towards the structural basis of peptide binding to dipeptidyl peptidases of Porphyromonas sp.2015

    • Author(s)
      Bezerra, G. A., Ohara-Nemoto, Y., Nemoto, T.K., Djinovic-Carugo, K.
    • Organizer
      2015 Annual Meeting - American Crystallographic Association
    • Place of Presentation
      Philadelphia (USA)
    • Year and Date
      2015-07-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] 歯周病原性‘red complex species’のビルレンス因子としてのプロテアーゼ2015

    • Author(s)
      下山佑,中里茉那美,根本優子,根本孝幸,石河太知,八重柏隆,佐々木実,木村重信
    • Organizer
      第69回 日本細菌学会東北支部総会
    • Place of Presentation
      郡山ビッグア( 郡山市)
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] 歯周病原性‘red complex species’のビルレンス因子としてのプロテアーゼ2015

    • Author(s)
      下山佑,中里茉那美,根本優子,根本孝幸,石河太知,八重柏隆,佐々木実,木村重信
    • Organizer
      日本細菌学会東北支部総会
    • Place of Presentation
      郡山市、郡山ビッグアイ
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Oral bacteria and systemic diseases: Periodontopathic bacteria and type 2 diabetes mellitus2015

    • Author(s)
      Ohara-Nemoto, Y., and Nemoto, T.K.
    • Organizer
      1st Partnership Symposium of Nagasaki and Islamic Universities
    • Place of Presentation
      Kushtia (Bangladesh)
    • Year and Date
      2015-09-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Tannerella forsythia のジペプチジルペプチダーゼ4の性状解析2015

    • Author(s)
      中里茉那美,下山佑,根本優子,根本孝幸,高橋晋平,石河太知,佐々木実,八重柏隆,木
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟市、朱鷺メッセ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] アシルオリゴペプチジルペプチダーゼ活性を有する歯周病原性細菌の新規ペプチダーゼ2015

    • Author(s)
      根本孝幸,根本優子
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      朱鷺メッセ( 新潟市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Tannerella forsythia のジペプチジルペプチダーセ4の性状解析2015

    • Author(s)
      中里茉那美,下山佑,根本優子,根本孝幸,高橋晋平,石河太知,佐々木実,八重柏隆,木村重信
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      朱鷺メッセ( 新潟市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] 非RI蛍光試薬によるPorphyromonas gingivalisのアミノ酸とジペプチドの取り込みの評価2015

    • Author(s)
      小早川健,根本優子,馬場友巳,根本孝幸
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟市 朱鷺メッセ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-25462893
  • [Presentation] 非RI蛍光試薬によるPorphyromonas gingivalisのアミノ酸とジペプチドの取り込みの評価2015

    • Author(s)
      小早川健,根本優子,馬場友巳,根本孝幸
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟市、朱鷺メッセ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] Identification of exopeptidases expressed in periodontopathic bacteria, Porphyromonas gingivalis and Porphyromonas endodontalis2015

    • Author(s)
      Nemoto, T.K., and Ohara-Nemoto, Y.
    • Organizer
      1st Partnership Symposium of Nagasaki and Islamic Universities
    • Place of Presentation
      Kushtia (Bangladesh)
    • Year and Date
      2015-09-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] 2種類のビスフォスフォネートの骨芽細胞におけるアルカリフォスファターゼ活性 および基質形成に対する異なる効果2015

    • Author(s)
      馬場友巳,宮崎敏博,根本優子,根本孝幸
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟市、朱鷺メッセ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] アシルオリゴペプチジルペプチダーゼ活性を有する歯周病原性細菌の新規ペプチダーゼ2015

    • Author(s)
      根本孝幸,根本優子
    • Organizer
      第57回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟市、朱鷺メッセ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K11047
  • [Presentation] 歯周病原性細菌の新規オリゴペプチダーゼの基質特異性と分子集合解離機構2014

    • Author(s)
      根本孝幸,小野俊雄,下山佑,木村重信,根本 優子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-25462893
  • [Presentation] 新規ジペプチジルペプチダーゼと歯周病原性細菌のタンパク質分解・取り込み機構の解明2014

    • Author(s)
      根本孝幸
    • Organizer
      発酵研究所第8回助成研究報告会
    • Place of Presentation
      大阪府豊中市(千里ライフサイエンスセンター)
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] 歯周病原性細菌の新規オリゴペプチダーゼ:基質特異性と分子集合性2014

    • Author(s)
      根本孝幸,根本優子,小野俊雄, 下山佑,木村重信
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-25462893
  • [Presentation] Towards the structural basis of peptide binding to dipeptidyl peptidase 11 of Porphyromonas gingivalis.2013

    • Author(s)
      Bezerra GA, Ohara-Nemoto Y, Nemoto TK, Djinovic-Carugo K
    • Organizer
      RAMC (Recent Advances in Macromolecular Crystallization)
    • Place of Presentation
      Bischoffsheim, France
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Dipeptide production in Porphyromonas gingivalis mediated by dipeptidyl peptidases and gingipains.2013

    • Author(s)
      Ohara-Nemoto Y, Abdur-Rouf S M, Shimoyama Y, Kimura S, Nemoto TK
    • Organizer
      113rd General Meeting of ASM
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Towards the structural basis of peptide binding to dipeptidyl peptidase 11 of Porphyromonas gingivalis.2013

    • Author(s)
      Bezerra, G. A., Ohara-Nemoto, Y., Nemoto, T.K., Djinovic-Carugo, K.
    • Organizer
      Recent Advances in Macromolecular Crystallization
    • Place of Presentation
      Le Bischenberg Conference Centre (Strasbourg, France)
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Nested PCRを用いた小児口腔へのPorphyromonas gingivalis 線毛タイプ別感染実態の検討 (Distribution of Porphyromonas gingivalis fimA genotypes in children using by nested PCR)2013

    • Author(s)
      下山佑,木村美澄,佐々木実,根本優子,古玉芳豊,上戸幸美,田中光郎,木村重信
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉県千葉市(幕張メッセ国際会議場)
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Identification and Characterization of Dipeptidyl-Peptidase V as a Member for Dipeptide Production in Porphyromonas gingivalis.2013

    • Author(s)
      根本孝幸,ラオフ シャーク ムハマド アブドゥー,根本優子,下山佑,木村重信
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      神奈川県横浜市(パシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Distribution of Porphyromonas gingivalis fimA genotypes in the children’s plaques.2013

    • Author(s)
      Shioyama, Y., Ohara-Nemoto, Y., Kimura, M., Sasaki, M., Tanaka, M., and Kimura, S.
    • Organizer
      113rd General meeting of ASM
    • Place of Presentation
      The Colorado Convention Center (Denver, USA)
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Identification and Characterization of Dipeptidyl-Peptidase V as a Member for Dipeptide Production in Porphyromonas gingivalis.2013

    • Author(s)
      根本孝幸,ラオフ シャーク ムハマド アブドゥー,根本優子,下山佑,木村重信
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-25462893
  • [Presentation] Distribution of Porphyromonas gingivalis fimA genotypes in the children’s plaques.2013

    • Author(s)
      Shioyama Y. Ohara-Nemoto Y, Kimura M, Sasaki M, Tanaka M, Kimura S
    • Organizer
      113rd General Meeting of ASM
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Identification and Characterization of Dipeptidyl-Peptidase V as a Member for Dipeptide Production in Porphyromonas gingivalis.2013

    • Author(s)
      根本孝幸,ラオフ シャーク ムハマド アブデュー,根本優子,下山佑,木村重信
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Porphyromonas endodontalisの発現するユニークなジペプチジルペプチダーゼ(DPP)VおよびDPP72013

    • Author(s)
      柳瀬絵美,根本優子,下山佑,木村重信,馬場友巳,根本孝幸
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山県岡山市(岡山コンベンションセンター))
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Porphyromonas endodontalisの発現するユニークなジペプチジルペプチダーゼ(DPP)VおよびDPP7.2013

    • Author(s)
      柳瀬絵美,根本優子,下山佑,木村重信,馬場友巳,根本孝幸
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Dipeptide production in Porphyromonas gingivalis mediated by dipeptidyl peptidases and gingipains.2013

    • Author(s)
      Ohara-Nemoto, Y., Abdur-Rouf, S. M., Shimoyama, Y., Kimura, S., and Nemoto, T. K.
    • Organizer
      113rd General meeting of ASM
    • Place of Presentation
      The Colorado Convention Center (Denver, USA)
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Porphyromonas endodontalisの発現するユニークなジペプチジルペプチダーゼ(DPP)VおよびDPP7.2013

    • Author(s)
      柳瀬絵美,根本優子,下山佑,木村重信,馬場友巳,根本孝幸
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25462893
  • [Presentation] Dipeptide production and assimilation in Porphyromonas gingivalis by four dipeptidyl peptidases.2012

    • Author(s)
      Rouf SMA, Ohara-Nemoto Y, Nemoto TK:
    • Organizer
      The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases and The 11th Nagasaki-Singapore Medical Symposium
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] S46ファミリーペプチダーゼ(DPP7/DPP11)の分類とDPP11サブタイプの同定.第54回歯科基礎医学学術大会2012

    • Author(s)
      根本孝幸,Rouf SMA,小野俊雄,下山 佑,木村重信,根本優子
    • Organizer
      第54回歯科基礎医学学術大会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Expression and characterization of dipeptidyl-peptidases of Porphyromonas gingivalis.2012

    • Author(s)
      Rouf SMA, Ohara-Nemoto Y, Yanase A, Ono T, Nemoto TK
    • Organizer
      1st International Conference on Porphyromonas gingivalis and Related Bacterial Species
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Expression and Characterization of Dipeptidyl- Peptidases of Porphyromonas gingivalis2012

    • Author(s)
      Rouf, S.M.A., Ohara-Nemoto, Y, Yanase, A., Ono, T., Nemoto, T.K
    • Organizer
      1st International Conference on Porphyromonas gingivalis and Related Bacterial Species
    • Place of Presentation
      Nagasaki, Japan
    • Year and Date
      2012-08-27
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Expression and Characterization of Dipeptidyl-Peptidases of Porphyromonas gingivalis2012

    • Author(s)
      Rouf, Shakh M. A., Ohara-Nemoto, Y., Yanase, A., Ono T., and Nemoto, T. K.
    • Organizer
      1st International Conference on Porphyromonas gingivalis and Related Bacterial Species
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 表皮剥脱毒素ETAの生物活性とプロテアーゼ活性の関係2012

    • Author(s)
      達聖月, 小早川健, 根本孝幸, 馬場友巳, 根本優子
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Dipeptide production and assimilation in Porphyromonas gingivalis by four dipeptidyl peptidases2012

    • Author(s)
      Rouf, Shakh M. A., Ohara-Nemoto, Y., and Nemoto, T. K.
    • Organizer
      Nagasaki University Global COE symposium
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Substrate specificity of four dipeptidyl peptidases from Porphyromonas gingivalis and the dipeptide repertoire produced by the bacterium2012

    • Author(s)
      柳瀬絵美,ラオフ アブドユー,小野俊夫,根本優子,根本孝幸
    • Organizer
      第54回歯科基礎医学学術大会
    • Place of Presentation
      郡山市
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Dipeptide production and assimilation in Porphyromonas gingivalis by four dipeptidyl peptidases. Nagasaki University Global COE symposium2012

    • Author(s)
      Rouf, S.M.A., Ohara-Nemoto, Y., Nemoto, T.K.
    • Organizer
      The 6th Nagasaki Symposium on Tropical and Emerging Infectious Diseases and The 11th Nagasaki-Singapore Medical Symposium
    • Place of Presentation
      Nagasaki, Japan
    • Year and Date
      2012-12-10
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Porphyromonas属菌が産生するAsp/Glu特異的新規ジペプチジルペプチダーゼ(DPP)11の同定と基質特異性の検討2012

    • Author(s)
      根本孝幸, SMAラオフ, 小野俊雄,下山佑,木村重信,根本優子
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎市
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 表皮剥脱毒素 ETA の生物活性とプロテアーゼ活性の相関性2012

    • Author(s)
      達聖月,小早川健,根本孝幸,馬場友巳,根本優子
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎市
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Porphyromonas属菌が産生するAsp/Glu特異的新規ジペプチジルペプチダーゼ(DPP)11の同定と基質特異性の検討2012

    • Author(s)
      根本孝幸
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 4種のPorphyromonas gingivalisジペプチジルペプチダーゼの基質特異性と産生ジペプチドレパートリー2012

    • Author(s)
      柳瀬絵見,Rouf SMA,小野俊雄,根本優子,根本孝幸
    • Organizer
      第54回歯科基礎医学学術大会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] DPP 7と新規Asp/ Glu特異的DPP11を含むS46ペプチダーゼファミリーの再分類2012

    • Author(s)
      シャークラオフ, 根本優子, 小野俊雄, 星野倫範, 藤原卓, 根本孝幸
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Colonization of Porphyromonas gingivalis in the plaques from mothers and their children2012

    • Author(s)
      Kimura, M., Shimoyama, Y., Ohara-Nemoto, Y., Kimura, S. and Tanaka, M.
    • Organizer
      11th Congress of the European Academy of Paediatric Dentistry
    • Place of Presentation
      Strasbourg, France
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 歯周病原性細菌の生育における新規のペプチダーゼDPPの重要性2012

    • Author(s)
      哲翁ふみ,柳瀬絵見,アブドューラオフ,根本孝幸,根本優子
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Classification and essential amino acid residues of the dipeptidyl peptidase 7/11 family in the Cytophaga- Flavobacterium-Bacteroides group2012

    • Author(s)
      Ohara-Nemoto, Y., Rouf, S.M.A., Hoshino, T., Fujiwara, T., Shimoyama, Y., Kimura, S., Ono, T., Nemoto, T.K.
    • Organizer
      112th General Meeting of ASM
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2012-06-18
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Classification and essential amino acid residues of the dipeptidyl peptidase 7/11 family in the Cytophaga-Flavobacterium-Bacteroides group2012

    • Author(s)
      Ohara-Nemoto, Y., Abdur-Rouf, S. M., Hoshino, T., Fujiwara, T., Shimoyama, Y., Kimura, S., Ono, T., and Nemoto, T. K.
    • Organizer
      112th General Meeting of American Society for Microbiology
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Classification of the S46 (DPP7/DPP11) family members and identification of a subtype of DPP112012

    • Author(s)
      根本孝幸,ラオフ アブドユー,小野俊夫,下山佑,木村重信,根本優子
    • Organizer
      第54回歯科基礎医学学術大会
    • Place of Presentation
      郡山市
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Porphyromonas属新規Asp/ Glu特異的ジペプチジルペプチダーゼの同定2012

    • Author(s)
      根本孝幸, シャークラオフ, 小野俊雄, 下山佑, 木村重信, 根本優子
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas gingivalisDPP11の酵素活性とAsp/Glu特異性を規定するArg6702011

    • Author(s)
      根本孝幸,木村重信,下山佑,木村重信,根本優子
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜市
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 骨芽細胞に発現するアクアポリン2011

    • Author(s)
      馬場友巳, 宮崎敏博, 達聖月, 根本優子, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Biochemical characterization of DPP11 : Importance of arginine^<670> for the enzymatic activity specific for the P1-position acidic residue.2011

    • Author(s)
      Nemoto TK, Ono T, Rouf SMA, Shimoyama Y, Kimura S, Tetsuo F, and Ohara-Nemoto Y
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas gingivalis DPP11の酵素活性とAsp/ Glu特異性を規定するArg^<670>2011

    • Author(s)
      根本孝幸, 小野俊雄, 下山佑, 木村重信, 根本優子
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Biochemical characterization of DPP11 : Importance of arginine670 for the enzymatic activity specific for the P1-position acidic residue2011

    • Author(s)
      Nemoto TK, Ono T, Rouf SMA, Shimoyama Y, Kimura S, Tetsuo F, Ohara-Nemoto Y
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館京都
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Rapid identification of Abiotrophia/ Granulicatella species using by 16S rRNA based PCR and RFLP2011

    • Author(s)
      Shimoyama Y, Sasaki M, Ohara-Nemoto Y, and Nemoto TK, Ishikawa T, Kimura S
    • Organizer
      4th International Symposium for Interface Oral Health Science
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas gingivalis DPP11の酵素活性とAsp/Glu特異性を規定するArg6702011

    • Author(s)
      根本孝幸, 小野俊雄, 下山佑, 木村重信, 根本優子
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] 表皮剥脱毒素ETA N末端領域の生物活性に及ぼす作用2011

    • Author(s)
      達聖月, 根本優子, 馬場友巳, 小早川健, 藤田修一, 池田通, 大井久美子, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas属菌が産生するAsp/Glu特異的新規ジペプチジルペプチダーゼ(DPP)112011

    • Author(s)
      根本優子,下山佑,木村重信,根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜市
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Auto-catalytic propeptide processing facilitates the final hetero-catalytic maturation of glutamyl endopeptidase GluV82011

    • Author(s)
      Ohara-Nemoto Y, Rouf SMA, Shimoyama Y, Kimura S, Ono T, Nemoto TK
    • Organizer
      111th General Meeting of American Society for Microbiology
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Auto-catalytic propeptide processing facilitates the final hetero-catalytic maturation of glutamyl endopeptidase GluV82011

    • Author(s)
      Ohara-Nemoto Yuko
    • Organizer
      111th General Meeting of American Society for Microbiology
    • Place of Presentation
      The Ernest N.Morial Convention Center (New Orleans, USA)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] A novel Asp and Glu specific dipeptidyl peptidase from Porphyromnas endodontalis2011

    • Author(s)
      Tetsuo F, Ohara-Nemoto Y, Shimoyama Y, Kimura S, Nemoto TK
    • Organizer
      38th Asia Pacific Dental Students Association Congress, Scientific Research Competition
    • Place of Presentation
      バンコクタイ
    • Year and Date
      2011-08-17
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas属菌が産生するAsp/Glu特異的新規ジペプチジルペプチダーゼ(DPP)112011

    • Author(s)
      根本優子
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場(岐阜市)
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 表皮剥脱毒素ETA N末端領域の生物活性に及ぼす作用2011

    • Author(s)
      達聖月, 根本優子, 馬場友巳, 小早川健, 藤田修一, 池田通, 大井久美子, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Porphyromonas属菌が産生するAsp/ Glu特異的新規ジペプチジルペプチダーゼ(DPP) 112011

    • Author(s)
      根本優子, 下山佑, 木村重信, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] 骨芽細胞に発現するアクアポリン2011

    • Author(s)
      馬場友巳, 宮崎敏博, 達聖月, 根本優子, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] 表皮剥奪毒素ETA N 末端領域の生物活性に及ぼす作用2011

    • Author(s)
      達聖月,根本優子,馬場友巳,小早川健,藤田修一,池田通,大井久美子,根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      岐阜市
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Porphyromonas属菌が産生するAsp/Glu特異的新規ジペプチジルペプチダーゼ(DPP)112011

    • Author(s)
      根本優子, 下山佑, 木村重信, 根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      長良川国際会議場岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Auto-catalytic propeptide processing facilitates the final hetero-catalytic maturation of glutamyl endopeptidase GluV82011

    • Author(s)
      Ohara-Nemoto, Y, Rouf, S.M.A, Shimoyama, Y., Kimura, S., Ono, T., Nemoto, T.K.
    • Organizer
      111th General Meeting of AmericanSociety for Microbiology
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Autocatalytic propeptide processing facilitates the final hetero-catalytic maturation of glutamyl endopeptidase GluV82011

    • Author(s)
      Ohara-Nemoto Y, Rouf SMA, Shimoyama Y, Kimura S, Ono T, and Nemoto TK
    • Organizer
      111th General Meeting of American Society for Microbiology
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] A novel Asp and Glu specific dipeptidyl peptidase from Porphyromonas endodontalis. 38th Asia Pacific Dental Students Association Congress2011

    • Author(s)
      Tetsuo F, Ohara-Nemoto Y, Shimoyama Y, Kimura S, and Nemoto TK
    • Organizer
      Scientific Research Competition, Babcock
    • Place of Presentation
      Thailand
    • Year and Date
      2011-08-17
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Biochemical characterization of DPP11 : Importance of arginine670 for the enzymatic activity specific for the P1-position acidic residue2011

    • Author(s)
      根本孝幸
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] Porphyromonas gingivalis DPP11の酵素活性とAsp/Glu特異性を規定するArg6702011

    • Author(s)
      根本孝幸
    • Organizer
      第53回歯科基礎医学学術大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] SLPI production from gingival epithelial cells against Porphyromonas gingivalis infection2010

    • Author(s)
      Ishikawa T, Ohara-Nemoto Y, Shimoyama Y, Sasaki M, Kimura S
    • Organizer
      88th General Session of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Prediction of colonization of periodontopathogens in plaque by VSC measurement2010

    • Author(s)
      Kishi M, Ohara-Nemoto Y, Kimura S, Aizawa F, Kishi K, Takahashi M, Yonemitsu M
    • Organizer
      88th General Session of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Structural chemistry of Staphylococcal aureus glutamyl endopeptidases2010

    • Author(s)
      Ohara-Nemoto Y, Rouf SMA, Shimoyama Y, Kimura S, Nemoto TK
    • Organizer
      88th General Session of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Structural chemistry of Staphylococcal aureus glutamyl endopeptidases.2010

    • Author(s)
      Ohara-Nemoto Yuko
    • Organizer
      88th General Session of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 新規V8プロテアーゼファミリー遺伝子のクローニングとV8プロテアーゼ活性に重要なN末バリンと185-195領域の同定2010

    • Author(s)
      根本孝幸
    • Organizer
      第52回歯科基礎医学学術大会
    • Place of Presentation
      東京都
    • Year and Date
      2010-09-21
    • Data Source
      KAKENHI-PROJECT-22592070
  • [Presentation] 新規V8プロテアーゼファミリー遺伝子のクローニングと8プロテアーゼ活性に重要なN末バリンと185-195領域の同定2010

    • Author(s)
      根本孝幸, 小野俊雄, 下山佑, 木村重信, 大河原久実, 根本優子
    • Organizer
      第52回歯科基礎医学学術大会
    • Place of Presentation
      松戸
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] 新規V8プロテアーゼファミリー遺伝子のクローニングとV8プロテアーゼ活性に重要なN末バリンと185-195領域の同定2010

    • Author(s)
      根本孝幸
    • Organizer
      第52回歯科基礎医学学術大会
    • Place of Presentation
      東京都
    • Year and Date
      2010-09-21
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Structural chemistry of Staphylococcal aureus glutamyl endopeptidases.2010

    • Author(s)
      Yuko Ohara-Nemoto
    • Organizer
      88th General Session of International Association for Dental Research
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Autocatalytic processing of prosequence prior to maturation of Staphylococcal glutamyl endopeptidases2010

    • Author(s)
      Shakh M. A. Rouf, 根本優子, 小野俊雄, 下山佑, 木村重信, 根本孝幸
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Staphylococcus属Glu-プロテアーゼの発現と酵素活性を決定する3アミノ酸の同定2009

    • Author(s)
      根本孝幸, 小野俊雄, 根本優子
    • Organizer
      第51回歯科基礎医学学術大会
    • Place of Presentation
      第51回歯科基礎医学学術大会
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Three amino acid residues define the proteolytic activities of Staphylococcal Glu-specific proteases2009

    • Author(s)
      Ohara-Nemoto Y, Ono T, Shimoyama Y, 6 Kimura S, Nemoto TK
    • Organizer
      109th General Meeting of American Society for Microbiology
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] A novel aspartate-specific dipeptidylpeptidase produced from Porphyromonas endodontalis2009

    • Author(s)
      Haraga H, Ohara-Nemoto Y, Nemoto TK, Shimoyama Y, Sasaki M, Kimura S
    • Organizer
      3rd International Symposium for Interface Oral Health Science in Sendai
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] The production of secretory leukocyte protease inhibitor(SLPI) from gingival epithelial cells in response to Porphyromonas gingivalis lipopolysaccharides2009

    • Author(s)
      Ishikawa T, Ohara-Nemoto Y, Tajika S, Sasaki M, Kimura S
    • Organizer
      3rd International Symposium for Interface Oral Health Science in Sendai
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Staphylococcus属Glu-プロテアーゼの発現と酵素活性を決定する3アミノ酸の同定.2009

    • Author(s)
      根本孝幸, 小野俊雄, 根本優子
    • Organizer
      第51回歯科基礎医学学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-21592367
  • [Presentation] Amino acid substitutions observed in human Hsp90 isoforms that impede the dimeric interaction2008

    • Author(s)
      Nemota TK, Kobayakawa T, Ono T, Yamada S, Mizuno A, Baba TT, Ohara-Nemoto Y
    • Organizer
      2nd World Conference of Stress/ 3rd Cell Stress Society International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      ハンガリー、ブダペスト
    • Year and Date
      2008-08-23
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] 筋管形成阻害に対するスタチンの影響2007

    • Author(s)
      馬場 友巳, 小野 俊雄, 根本 孝幸, 宮崎 敏博
    • Organizer
      第49回歯科基礎医学会学術大会,
    • Place of Presentation
      札幌
    • Year and Date
      2007-08-31
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] The single nucleotide polymorphism Hsp90α(Gln488His) causes the impedance of dimer formation2007

    • Author(s)
      Nemoto, T, Kobayakawa, T, Ohara-Nemoto, Y
    • Organizer
      2nd Congress of the Biomedical Society for Stress Response
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2007-10-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Pathogenic Factors of Porphyromonas endodontalis2007

    • Author(s)
      Haraga H, Ohara-Nemoto Y, Nemoto T K, Sasaki M, Tajika S, Hamada S, Kimura S
    • Organizer
      107th ASM General Meeting
    • Place of Presentation
      カナダ、トロント
    • Year and Date
      2007-07-20
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Amino acid substitutions observed in human Hsp90 isoforms that impede the dimeric interaction2007

    • Author(s)
      Nemoto TK, Kobayakawa T, Ono T, Yamada S, Mizuno A, Baba TT, Ohara-Nemoto Y
    • Organizer
      2nd World Conference of Stress/3rd Cell Stress Society International Congress on Stress Res onses in Biolo and Medicine
    • Place of Presentation
      ハンガリー、ブダペスト
    • Year and Date
      2007-08-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Pathogenic Factors of Porplryromonas endodontalis2007

    • Author(s)
      Haraga H, Ohara-Nemoto Y, Nemoto TK, Sasaki M, Tajika S, Hamada S, Kimura S
    • Organizer
      107th ASM General Meeting
    • Place of Presentation
      カナダ、トロント
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Dual roles of the prosequence of glutamic acid-specific endopeptidase from Staphylococcus aureus2007

    • Author(s)
      Ono, T, Ohara-Nemoto, Y, Shimoyama, Y, Kimura, S, Takagi, T, Nemoto, TK
    • Organizer
      30th Japanese Society of Molecular Biology and 81st Congress of Japanese Biochemical Society
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Pathogenic Factors of Porphyromonas endodontalis2007

    • Author(s)
      Haraga, H, Ohara-Nemoto, Y, Nemoto, TK, Sasaki, M, Tajika, S, Hamada, S, Kimura, S
    • Organizer
      107th ASM General Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Dual roles of the prosequence of glutamic acid-specific endopeptidase from Staphylococcus aureus2007

    • Author(s)
      Ono T, Ohara-Nemoto Y, Shimo yama Y, Kimura S, Takagi T, Nemoto T K
    • Organizer
      第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] 筋管形成阻害に対するスタチンの影響2007

    • Author(s)
      馬場 友巳, 小野 俊雄, 根本 孝幸, 宮崎 敏博
    • Organizer
      第49回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2007-08-31
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Dual roles of the prosequence of glutamic acid-specific endopeptidase from Staphylococcus aureus2007

    • Author(s)
      Ono T, Ohara-Nemoto Y, Shimoyama Y, Kimura S, Takagi T, Nemoto TK
    • Organizer
      第30回日本分子生物学会年会, 第80回目本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Amino acid substitutions observed in human Hsp90 isoforms that impede the dimeric interaction2007

    • Author(s)
      Nemoto, TK, Kobayakawa, T, Ono, T, Yamada, S, Mizuno, A, Baba, TT, Ohara-Nemoto, Y
    • Organizer
      2nd World Conference of Stress and 3rd Cell Stress Society International Congress on Cell Stress Responses in Biology and Medicine
    • Place of Presentation
      Budapest, Hungary
    • Year and Date
      2007-08-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Impeded dimer formation caused by the SNP Gln488His of human Hsp90α2007

    • Author(s)
      Kobayakawa, T, Yamada, S, Ohara-Nemoto, Y, Mizuno, A, Nemoto, TK
    • Organizer
      30th Japanese Society of Molecular Biology/ 81st Congress of Japanese Biochemical Society
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-12-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] ヒトhsp90αSNPGln488>His変異によるHsp90ダイマー形成能の低下2007

    • Author(s)
      小早川 健, 山田 慎一, 根本 優子, 水野 明夫, 根本 孝幸
    • Organizer
      第30回日本分子生物学会年会, 第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] ヒト hsp90α SNP GIn488>His変異によるHsp90ダイマー形成能の低下2007

    • Author(s)
      小早 川健, 山田 慎一, 根本 優子, 水野 明夫, 根本 孝幸
    • Organizer
      第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Hsp90α遺伝子多型Gln488>Hisはダイマー形成能の低下をきたす2007

    • Author(s)
      根本 孝幸, 小早川 健, 根本 優子
    • Organizer
      第2回臨床ストレス応答学会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Hsp90α遺伝子多型Gln488>Hisはダイマー形成能の低下をきたす.2007

    • Author(s)
      根本 孝幸, 小早 川健, 根本 優子
    • Organizer
      第2回臨床ストレス応答学会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-01
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] Effect of statins on the inhibition of myotube differentiation of C2C12 cells2007

    • Author(s)
      Baba, TT, Ono, T, Nemoto, TK, Miyazaki, T
    • Organizer
      49th Annual Meeting of Japanese Association for Oral Biology
    • Place of Presentation
      Sapporo, Japan
    • Year and Date
      2007-08-31
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592039
  • [Presentation] 歯周病原性細菌の新規オリゴペプチダーゼの基質特異性と分子集合解離機構

    • Author(s)
      根本孝幸,小野俊雄,下山佑,木村重信,根本優子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都市)
    • Year and Date
      2014-10-15 – 2014-10-17
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] SLPIによるPorphyromonas gingivalisに対する感染抑制作用

    • Author(s)
      下山佑,石河太知,根本優子,根本孝幸,佐々木実,木村重信
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] Mechanism on oligomer-monomer transition of a novel oligopeptidase from periodontopathic bacterium.

    • Author(s)
      根本孝幸,小野俊雄,下山佑,木村重信,根本優子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都
    • Year and Date
      2014-10-15 – 2014-10-17
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] SLPIによるPorphyromonas gingivalisに対する感染抑制作用

    • Author(s)
      下山佑,石河太知,根本優子,根本孝幸,佐々木実,木村重信
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] 歯周病原性細菌の新規オリゴペプチダーゼ:基質特異性と分子集合性

    • Author(s)
      根本孝幸,根本優子,小野俊雄,下山佑,木村重信
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24592809
  • [Presentation] 歯周病原性細菌の新規オリゴペプチダーゼ:基質特異性と分子集合性

    • Author(s)
      根本孝幸,根本優子,小野俊雄,下山佑,木村重信
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25462894
  • [Presentation] Laminins 411 and 421 differentially promote tumor cell migration via alpha6beta1 integrin and MCAM.

    • Author(s)
      石河太知,下山佑,根本優子,佐々木実,木村重信
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      岐阜市
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24592809
  • 1.  NEMOTO Yuko (10164667)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 199 results
  • 2.  KOBAYAKAWA Takeshi (10153587)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 35 results
  • 3.  BABA Tomomi (60189727)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 29 results
  • 4.  KYAKUMOTO Seiko (90118274)
    # of Collaborated Projects: 7 results
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  • 5.  ONO Toshio (80050607)
    # of Collaborated Projects: 7 results
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  • 6.  KIMURA Shigenobu (10177917)
    # of Collaborated Projects: 7 results
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  • 7.  SHIMOYAMA Yu (90453331)
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  • 8.  NAGAI Masazumi (00217960)
    # of Collaborated Projects: 4 results
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  • 9.  NAKAYAMA Koji (80150473)
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  • 10.  TANAKA Ki-ichiro (50001954)
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    # of Collaborated Projects: 3 results
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  • 13.  SASAKI Minoru (40187133)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 14.  HOTOKEZAKA Hitoshi (90199513)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  KUROKAWA Riki (70170107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  BABA Tomomi (60189717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ITO Kiyoshi (50201926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  TSUKAZAKI Tomoo (50315230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FUJITA Syuichi (00181355)
    # of Collaborated Projects: 1 results
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  • 22.  SHIBATA Yasuaki (80253673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  INOKUCHI Tsugio (40136685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  OHBA Seigo (80363456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YAMADA Shin-ichi (50380853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 26.  KANATANI Naoko (10380982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  宮川 勇 (50136165)
    # of Collaborated Projects: 1 results
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  • 28.  山口 朗 (00142430)
    # of Collaborated Projects: 1 results
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  • 29.  森田 幸子 (00631574)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  坂井 詠子 (10176612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  石河 太知 (10569247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  中里 茉那美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 37.  池田 通
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  井奥 洪二
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    # of Collaborated Products: 1 results
  • 39.  上高原 理暢
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