MIYATA TOSHIYUKI 宮田敏行

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MIYATA Toshiyuki 宮田敏行

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Researcher Number	90183970
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Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員 2015 – 2019: 国立研究開発法人国立循環器病研究センター, 病院, 非常勤研究員 2017: 国立循環器病研究センター, シニア研究員 2015 – 2016: 国立研究開発法人国立循環器病研究センター, 病院, シニア研究員 2014: 国立循環器病研究センター研究所, 脳血管内科, シニア研究員 … More 2012 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 部長 2010 – 2011: National Cardiovascular Center Research Institute, 分子病態部, 部長 2009: National Cardiovascular Center Research Institute, 病因部, 部長 2005 – 2008: 国立循環器病センター(研究所), 病因部, 部長 2007: National Cardiovascular Center Research Institute, 病因部, Director 2001 – 2004: 国立循環器病センター研究所, 病因部, 部長 1991 – 1999: 国立循環器病センター研究所, 脈管生理部, 室長 1986 – 1991: Faculty of Science, Kyushu University, Instructor, 理学部, 助手 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Hematology / 物質生物化学 / Basic Section 54010:Hematology and medical oncology-related / Structural biochemistry / Hematology / 医学一般 / Biological Sciences Except Principal Investigator 物質生物化学 / Hematology … More / Basic Section 56040:Obstetrics and gynecology-related / Biological Sciences / Basic Section 53050:Dermatology-related / Basic Section 55030:Cardiovascular surgery-related / Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine) / Pathological medical chemistry / Functional biochemistry / General medical chemistry / Obstetrics and gynecology / Kidney internal medicine Less
Keywords	Principal Investigator ADAMTS13 / ホモシステイン / thrombosis / 血管内皮細胞 / 血栓性血小板減少性紫斑病 / endothelial cells / homocysteine / 血栓 / 血栓症 / 凝固制御因子 … More / kidney / vascular disease / arteriosclerosis / Herp / 組織因子 / 血液凝固 / 静脈血栓塞栓症 / 血小板 / プロテインS / フォンビルブランド因子 / 静脈血栓症 / 血栓性素因 / Ndrg1 / demyelination / ニューロパチー / ノックアウトマウス / ミエリン / NDRG1 / 小胞体ストレス / phosphorylation / 小胞体 / 腎 / stress protein / 遺伝子解析 / 分子シャペロン / RTP / 動脈硬化 / diabetes / 臨床検査法 / 糖尿病 / 心筋梗塞 / 心血管系疾患 / ドメイン / NMR / Tissue factor / 第VII因子 / 機能異常分子 / 遺伝子変異 / トランスクリプトーム解析 / Bac-TRAP / トランスジェニックマウス / 遺伝子多型 / マウスモデル / 遺伝子 / 脳梗塞 / プロテアーゼ / 血小板凝集 / 組み換え体 / 血小板血栓 / 血栓症修飾遺伝子 / 第三世代シーケンサー / 次世代シーケンサー / プロトロンビンバリアント / 登録研究 / modifier / 特発性血栓症 / 変異体 / 静脈血栓症、 / 経口避妊薬 / Serine Protease / Factor IX Niigata / Fibrinogen -chain / Molecular Defect / Fibrin Monomer / Fibrinogen Nagoya / 遺伝病 / 分子異常症 / 血液凝固因子 / XII因子 / フィブリノーゲン / アミノ酸配列 / XII因子Washington D.C. / カリクレイン / 分子異常XII因子 / トリプシンペプチド地図 / セリンプロテアーゼ / IX因子新潟 / フィブリノーゲンγ鎖 / フィブリンモノマー / フィブリノーゲン名古屋 / genetic polymorphism / genetic engineered mouse / von Willbrand factor / Thrombocytopenia / Platelet / 血管障害 / 腎傷害 / 微小血管 / メタロプロテアーゼ / 一般住民 / 性差 / 遺伝子改変マウス / 血小板減少症 / Charcot-Marie-Tooth disease / endoplasmic reticulum stress / peripheral neuropathy / 耐糖脳 / 脳虚血 / 耐糖性 / Charcot-Marie-Tooth病 / 遺伝子欠失マウス / 末梢神経変性 / sensory impairment / mouse model / hereditary motor and sensory neuropathy / Homocysteine / loxP / 神経障害遺伝子 / 遺伝子欠失動物 / 神経軸索 / 脱ミエリン化 / 運動障害 / シュワン細胞 / 運動感覚障害 / 末梢神経傷害 / モデル動物 / 遺伝性運動感覚性ニューロパチー / 酸化LDL / リゾホスファチジルコリン / 分化 / 細胞傷害 / hyperhomocysteinemia / 動脈硬化症 / 高ホモシステイン血症 / 内皮傷害 / 細胞障害 / 内皮障害 / 糸球体 / 尿細管 / リン酸化 / ホモシテイン / molecular chaperone / thromobosis / 先天性欠損症 / 酸化脂質 / リン酸化蛋白質 / クローニング / domain / myocardial infarction / cerebral infarction / hemostasis / coagulation / tissue factor / 蛋白分解酵素 / 止血 / 凝固反応 / diagnosis / prethrombotic state / coronary artery disease / stroke / diabetics / cardiovascular disease / coagulation factor VII / 凝固亢進状態 / 凝固因子 / リスクファクター / 脳卒中 / 凝固第VII因子 / Domain / Three-dimensional structure / Blood coagulation / 立体構造 / Recombinant Protein / Thrombosis / Blood Coagulation / クロ-ニング / 酵母による発現 / 血栓形成 / Coagulation factor XII / Serine protease / Peptide map / Molecular defect / Coagulation factor IX / Hemophilia B / 血液凝固異常症 / フィブリノ-ゲン / 第IX因子 / 血友病 / 先天性異常症 / 血液凝固因子XII / セリンプロテア-ゼ / ペプチド地図 / 異常IX因子 / 血友病B / ライブイメージング / 血管内皮細胞プロテインC受容体 / プロテイン C 受容体 / トランスクリプトーム / マウス / プロテインC受容体 / トロンボモジュリン / 遺伝子発現 / 抗凝固機構 / バイオイメージング / 抗血栓性因子 / 肝星細胞 / 抗血栓因子 / フォンビルランド因子 / 凝固 / 結晶解析 / 立体構造解析 / プロラアーゼ … More Except Principal Investigator 遺伝子解析 / 静脈血栓塞栓症 / Factor VII / 血液凝固VII因子 / IX因子 / カブトガニ血球 / 補体因子 / Herp / 分子シャペロン / 小胞体ストレス / 遺伝性血管性浮腫 / C1インヒビター / 妊娠 / 抗凝固療法 / 遺伝性血栓性素因 / EGF様ドメイン / インテグリン / platelet / 血小板 / ADAMTS13 / 蛍光性ペプチド基質 / VII因子 / 体液プロテア-ゼ / cDNA cloning / Serine protease / タキプレシン / セリンプロテア-ゼ / 体液凝固 / プロスロンビン / リポ多糖 / 妊娠高血圧症候群 / プラスミノーゲン / プロテインS / ATF4 / ストレス蛋白質 / ストレス応答 / 血栓症 / 早期診断 / 血栓性疾患 / 線溶凝固系 / 血栓後症候群 / 凝固線溶系 / 接触系 / 全国調査 / 血管性浮腫 / ブラジキニン / 窒息 / 浮腫 / 中国 / 英国 / シンガポール / ハンガリー / 韓国 / 国際情報交換 / 栄養学 / 内科 / 遺伝学 / 予防治療戦略 / protein C / protein S / 予防治療戦 / 発症要因 / 国際学術調査 / プロテインC / アジア人 / シグナル伝達 / Synthetic chromogenic substrate / Synthetic fluorogenic substrate / Factor VII-monoclonal antibody / Mouse glandular kallikrein / Bllod clotting protease / マウス顎下腺カリクレイン / セリンプロテアーゼ / 凝固プロテアーゼ / 蛍光性ペプチド / VII因子モノクロ-ナル抗体 / 顎下腺カリクレイン / 可視性ペプチド基質 / gamma-Carboxyglutamic acid residue / Factor IX / Protein Z / Oligosaccharide / EGF-like domain / IX因子Fukuoka / エステル基質 / 分子異常症 / 血友病B / 血液凝固IX因子 / Tachyplesin / EGF domain / _2-GP-I domain / Factor C / Lipopolysaccharide / Horseshoe Crab Hemocyte / Hemolymph Coagulation / ホスファチジルグリセロール / スロンビン / 酸性リン脂質 / リポ多糖感受性セリンプロテアーゼチモーゲン(C因子) / コアギュローゲン / β_2-GP-I様ドメイン / リポ多糖(内毒素) / セリンプロテアーゼチモーゲン / β_2ーGPーI様ドメイン / C因子 / Blood coagulation factor / Abnormal molecule / Prothrombin / Fibrinogen / セリンプロテアーゼ前駆体 / 血液凝固因子 / 異常分子 / フィブリノーゲン / signaling molecule / integrin / シグナル伝達分子 / knockout mouse / thrombotic thrombocytopenic purpura / blood / enzyme / protease / von Willebrand factor / ノックアウトマウス / 血栓性血小板減少性紫斑病 / 血液 / 酵素 / プロテアーゼ / フォンビルブランド因子 / Esterase / Monoclonal antibody / Blood protease / gamma-Gla domain / Extrinsic coagulation / Synthetic Peptide substrate / tissue factor / X因子 / エステラ-ゼ / モノクロ-ナル抗体 / γーGlaドメイン / 外因系凝固反応 / 合成ペプチド基質 / 組織因子 / Bacterial endotoxin / beta-1, 3-glucan / Factor G / Factor B / Blood coagulation / Horseshoe crab / 抗菌性ペプチド / ゲノム解析 / トロンビン / Proclotting enzyme / 真菌類 / 無脊椎動物 / 体液凝固因子 / cDNAクロ-ニング / 細菌内毒素 / βー1,3ーグルカン / G因子 / B因子 / カブトガニ血球細胞 / 塩基配列 / 黄色ブドウ球菌 / SC遺伝子 / カルモジュリン / リピドA / グラム陰性菌 / 抗リポ多糖因子 / 胎児発育不全 / 子宮内胎児死亡 / 流産 / プロテインＳ K196E 変異 / プロテインＳ / 遺伝子異常 / 妊娠高血圧腎症 / 妊娠合併症 / 先天性血栓性素因 / 不育症 / Factor H自己抗体 / atypical HUS / H因子 / 第二経路 / 微小血管障害症 / 非典型溶血性尿毒症症候群 / C3 / Factor H / 補体 / aHUS / 日本人の血栓症 / 遺伝子変異 / ノックインマウス / 蛋白質品質管理 / 翻訳 / 品質管理 / 翻訳抑制 / RTP / 遺伝子発現 / 血管内皮細胞 / ホモシステイン Less

重度血栓後症候群患者における適切な治療を目指した遺伝学的及び臨床的特徴の解明
- Principal Investigator
  
  辻明宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  National Cardiovascular Center Research Institute
Developmental study to elucidate the abnormalities of the fibrinolytic and coagulation systems in hereditary angioedema
- Principal Investigator
  
  本田大介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Chiba University
妊娠関連血栓性疾患の治療量抗凝固療法の確立と遺伝子解析に関する研究
- Principal Investigator
  
  根木玲子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  National Cardiovascular Center Research Institute
Genetic background of thrombophilia using third generation DNA sequencingPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Cardiovascular Center Research Institute
Clarification of the pathogenesis of angioedema
- Principal Investigator
  
  Horiuchi Takahiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kyushu University
Pregnancy related thrombosis and anticoagulant therapy
- Principal Investigator
  
  Neki Reiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  National Cardiovascular Center Research Institute
Studies on thrombotic risk of protein S K196E mutationPrincipal Investigator
- Principal Investigator
  
  Miyata Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of the role of kindlin in the functional expression of beta3 integrins and investigation of the kindlin-related new molecules
- Principal Investigator
  
  Honda Shigenori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Adverse pregnancy outcome
- Principal Investigator
  
  NEKI REIKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Cardiovascular Center Research Institute
Investigation into thrombophilia indigenous to Asian populations and establishment of new strategy for preventing thrombosis
- Principal Investigator
  
  TSUDA Hiroko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nakamura Gakuen College
Analysis of molecular pathogenesis of thrombosis in Japanese using mice with genetic mutations in anticoagulation/fibrinolytic factors
- Principal Investigator
  
  Banno Fumiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Production and analysis of Bac-TRAP mice that express fluorescent proteins driven by thrombomodulin or endothelial cell protein C receptor promoterPrincipal Investigator
- Principal Investigator
  
  MIYATA TOSHIYUKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Establishment of the diagnostic system of patients with atypical hemolytic uremic syndrome, and analysis of the characteristics of aHUS patients in Japan
- Principal Investigator
  
  YOSHIDA Yoko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
  Nara Medical University
Thrombotic phenotypes of two antithrombotic factors, protein S and ADAMTS13Principal Investigator
- Principal Investigator
  
  MIYATA TOSHIYUKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Production and analysis of Adamts13-Bac-TRAP mice that express fluorescent protein EGFP driven by Adamts13 promoterPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
ADAMTS13の基質認識・切断に対する細胞外環境の効果Principal Investigator
- Principal Investigator
  
  宮田敏行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
Thrombosis due to dysfunction of anticoagulant activity and strategy for prevention of thrombosisPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Identification of signaling molecules associated with β3 integrins using random mutagenesis
- Principal Investigator
  
  HONDA Shigenori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Studies on causative gene for thrombotic thrombocytopenic purpura, ADAMTS13Principal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Physiological and biochemical analysis of VWF-cleaving protease ADAMTS13
- Principal Investigator
  
  KOKAME Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Herpノックアウトマウスの解析および小胞体ストレス時の翻訳機構に関する研究
- Principal Investigator
  
  小亀浩市
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
Functional analysis of endoplasmic reticulum stress-induced genes, NDRG1 and HERPUD1Principal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  NATIONAL CARDIO VA SCULAR CENTER, RESEARCH INSTITUTE
小胞体ストレス時の翻訳調節機構と小胞体膜タンパク質Herpの機能に関する研究
- Principal Investigator
  
  小亀浩市
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
Analysis of mice lacking for NDRG1 and its homolog.Principal Investigator
- Principal Investigator
  
  MIYATA Toshiuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
小胞体ストレス応答性新規蛋白質Herp及びRTPに関する研究
- Principal Investigator
  
  KOKAME Koichi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Cardiovascular Center Research Institute
Studies on genes involved in endothelial dysfunction involved in thrombosis and atherosclerosisPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Structural biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Studies on new proteins involved in vascular endothelial injuryPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Studies on genes involved in thrombois on endothelial cellsPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Structural biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Studies on the initiation of extrinsic blood coagulation reactionPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
New and rapid diagnostic method for cardiovascular disease and prothrombotic statePrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
Three-Dimensional Structure of Human Tissue FactorPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
Study on the extrinsic blood coagulationPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  National Cardiovascular Center Research Institute
Mechanism of Hemolymph Coagulation System in Invertebrates
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Studies on the Activity Measurement for Blood Proteases using their Monoclonal Antibodies
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
Structural Studies on Functional Abnormality of Fibrinogen and Factor IXPrincipal Investigator
- Principal Investigator
  
  MIYATA Toshiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  Kyushu University
黄色ブドウ球菌スタフィロコアグラーゼのタンパク質工学的解析
- Principal Investigator
  
  岩永貞昭
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Initiation Mechanism of Extrinsic Blood Coagulation System
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyushu University
Development of Synthetic Fluorogenic Peptide Substrates for Blood Clotting Proteases
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Hemolymph Coagulation and Defence Systems in Invertebrate Animals
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Structural studies on Functional Abnormality of Factor XII and Fibrinogen.Principal Investigator
- Principal Investigator
  
  ITO Akio, 宮田敏行
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
合成リピドAと特異的に結合するタンパク質の構造と機能相関
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
Studies on Molecular Abnormality of Blood Coagulation and Fibrinolytic Factors
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University

[Book] 第67回Scientific Standardization Committee 学術報告、Genomics in Thrombosis and Hemostasis2022
- Author(s)
  宮田敏行
- Total Pages
  14
- Publisher
  血栓止血情報センター
- Data Source
  KAKENHI-PROJECT-19K08875
[Book] 2020年度国際血栓止血学会SSC報告書、41-46頁2021
- Author(s)
  宮田敏行
- Total Pages
  197
- Publisher
  血栓止血情報センター
- Data Source
  KAKENHI-PROJECT-19K08875
[Book] 標準下肢静脈エコー、30-32頁2020
- Author(s)
  宮田敏行、光黒真菜
- Total Pages
  272
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-19K08875
[Book] 臨床脈管学2017
- Author(s)
  宮田敏行、辻明宏
- Total Pages
  2
- Publisher
  日本医学出版
- ISBN
  9784865770278
- Data Source
  KAKENHI-PROJECT-16K09834
[Book] Annual Review 血液 20142014
- Author(s)
  宮田敏行, 坂野史明
- Total Pages
  240
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25461465
[Book] よくわかる血栓・止血異常の診療2014
- Author(s)
  宮田敏行、田嶌優子
- Total Pages
  297
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-24390250
[Book] よくわかる血栓・止血異常の診療2014
- Author(s)
  宮田敏行、田嶌優子
- Total Pages
  297
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25670454
[Book] Annual Review 血液20142014
- Author(s)
  宮田敏行、坂野史明
- Total Pages
  240
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24390250
[Book] VI.凝固線溶系 3.内因系凝固反応と血栓症I Annual Review 血液 2012、高久史麿・小澤敬也・坂田洋一・金倉譲・小島勢二編集2012
- Author(s)
  宮田敏行、喜多俊行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23659494
[Book] Annual Review血液20122012
- Author(s)
  宮田敏行、喜多俊行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 「VI.凝固線溶系3.内因系凝固反応と血栓症」Annual Review血液(高久史麿・小澤敬也・坂田洋一・金倉譲・小島勢二編集)2012
- Author(s)
  宮田敏行、喜多俊行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20390278
[Book] Annual Review血液20122012
- Author(s)
  宮田敏行、喜多俊行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23659494
[Book] 脈管専門医のための臨床脈管学(「血液凝固・線溶の制御因子と血栓形成」)(日本脈管学会編)2010
- Author(s)
  宮田敏行
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 疾患モデルの作製と利用-循環器疾患2010
- Author(s)
  宮田敏行
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 疾患モデルの作製と利用-循環器疾患(「遺伝子改変血栓症モデル」)(北徹・堀内久徳・柳田素子・猪原匡史・冨本秀和・並河徹編集)2010
- Author(s)
  宮田敏行、水口純、坂野史明
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 静脈血栓塞栓症ガイドブック改訂2版2010
- Author(s)
  宮田敏行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 「遺伝子改変血栓症モデル」疾患モデルの作製と利用-循環器疾患(北徹・堀内久徳・柳田素子・猪原匡史・冨本秀和・並河徹編集)2010
- Author(s)
  宮田敏行、水口純、坂野史明
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20390278
[Book] Biology of an antithrombotic factor-ADAMTS13.Recent Advances in Thrombosis and Hemostasis 2008(K. Tanaka, E. W. Davie(Eds.) Y. Ikeda, S. Iwanaga, H. Saito, K. Sueishi(Associate Eds.))2008
- Author(s)
  F. Banno, T. Miyata
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20390278
[Book] 「肺血栓塞栓症」THE LUNG perspectives2006
- Author(s)
  宮田敏行
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17390285
[Book] 図説血栓・止血・血管学血栓症制圧のために第7章凝固・線溶・血小板・血管検査など 10 ゲノム,トランスクリプトーム,プロテオーム解析法(一瀬白帝編者)2005
- Author(s)
  奥田智彦, 宮田敏行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Fibrin and fibrinogen degradation products/D-dimer ratio can be a useful marker for differentiating an acute attack of hereditary angioedema from thrombotic conditions2024
- Author(s)
  Honda Daisuke、Ohsawa Isao、Miyata Toshiyuki、Ozaki Masayuki、Aizawa Masashi、Tomino Yasuhiko、Asanuma Katsuhiko
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 174-176
- DOI
  10.1016/j.alit.2023.08.001
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07759, KAKENHI-PROJECT-23K27614
[Journal Article] 【血栓に強くなる-産婦人科診療に活かす最新知識-】診断・治療「遺伝性・後天性血栓性素因と産科診療」2023
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  産科と婦人科
  
  Volume: 90巻 Pages: 1091-1097
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] 難治性疾患(難病)を学ぶ　特発性血栓症2023
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  遺伝子医学
  
  Volume: 13巻 Pages: 110-119
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] 【出血性疾患と血栓性疾患　実地医家が見落とさないためのポイント】血栓性疾患(先天性・後天性)　先天性血栓性疾患　先天性(遺伝性)アンチトロンビン・プロテインC・プロテインS欠乏症2023
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  Medical Practice
  
  Volume: 40巻 Pages: 916-920
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] Three Cases of Unprovoked Venous Thromboembolism with Prothrombin p.Arg596Gln Variant and a Literature Review of Antithrombin Resistance2023
- Author(s)
  Tsuji A, Miyata T, Sekine A, Neki R, Kokame K, Tomita T, et al.
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 6 Pages: 885-888
- DOI
  10.2169/internalmedicine.9718-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09530, KAKENHI-PROJECT-19K08875
[Journal Article] Biochemistry, molecular genetics, and clinical aspects of hereditary angioedema with and without C1 inhibitor deficiency2023
- Author(s)
  Miyata T, Horiuchi T
- Journal Title
  
  Allergol Int
  
  Volume: 72
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] P2Y12 Reaction Units and Clinical Outcomes in Acute Large Artery Atherosclerotic Stroke: A Multicenter Prospective Study2023
- Author(s)
  Fukuma K, Yamagami H, Ihara M, Tanaka T, Miyata T, Miyata S, Kokame K, Nishimura K, Nakaoku Y, Yamamoto H, Hayakawa M, Kamiyama K, Enomoto Y, Itabashi R, Furui E, Manabe Y, Ezura M, Todo K, Hashikawa K, Uchiyama S, Toyoda K, Nagatsuka K, and the PRAISE Study Investigators
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 1 Pages: 39-55
- DOI
  10.5551/jat.63369
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875, KAKENHI-PROJECT-22K15721
[Journal Article] 難治性疾患（難病）を学ぶ「特発性血栓症」2023
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  遺伝子医学
  
  Volume: 13(2) Pages: 110-119
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] FⅦaは血管内皮細胞が産生するマイクロパーテイクルの放出とmicroRNA 10aの送達を通して炎症とバリアー崩壊を抑制する2022
- Author(s)
  宮田敏行、根木玲子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 33(3) Pages: 369-371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] 血液凝固因子・凝固制御因子2022
- Author(s)
  宮田敏行、和田晋一
- Journal Title
  
  日本臨牀
  
  Volume: 80 Pages: 673-678
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] ヘパリン抵抗性―臨床的視点からと管理戦略2021
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32(6) Pages: 796-798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09277
[Journal Article] 内皮細胞プロテインC受容体の脂質の提示は凝固と自己免疫を結びつける2021
- Author(s)
  宮田敏行、根木玲子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32(4) Pages: 552-553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] ジャーナルクラブ「ヘパリン抵抗性　臨床的視点からと管理戦略」2021
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32 Pages: 796-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] 内皮細胞プロテインC受容体の脂質の提示は凝固と自己免疫を結びつける2021
- Author(s)
  宮田敏行、根木玲子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32(4) Pages: 552-553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09277
[Journal Article] Complement-related thrombosis2021
- Author(s)
  MIYATA Toshiyuki、INOUE Norimitsu
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 32 Issue: 6 Pages: 695-707
- DOI
  10.2491/jjsth.32.695
- NAID
  130008134369
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] Autoantibody-resistant ADAMTS13 variant2021
- Author(s)
  Miyata, T
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 19 Pages: 2575-2576
- DOI
  10.1182/blood.2021011147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] Current prophylactic plasma infusion protocols do not adequately prevent long-term cumulative organ damage in the Japanese congenital thrombotic thrombocytopenic purpura cohort2021
- Author(s)
  Sakai, K. Fujimura, Y. Miyata, T. Isonishi, A. Kokame, K. Matsumoto, M.
- Journal Title
  
  Br J Haematol,
  
  Volume: 194 Issue: 2 Pages: 444-452
- DOI
  10.1111/bjh.17560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] ヘパリン抵抗性―臨床的視点からと管理戦略2021
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32(6) Pages: 796-798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09530
[Journal Article] Clinical guidance for peripartum management of patients with hereditary thrombophilia.2021
- Author(s)
  Kobayashi T, Morishita E, Tsuda H, Neki R, Kojima T, Ohga S, Ochiai M, Adachi T, Miyata T
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 47 Issue: 9 Pages: 3008-3033
- DOI
  10.1111/jog.14879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09277, KAKENHI-PROJECT-18K07849, KAKENHI-PROJECT-19K08875, KAKENHI-PROJECT-21K09530
[Journal Article] Influence of renal impairment and genetic subtypes on warfarin control in Japanese patients.2021
- Author(s)
  Tanaka T, Ihara M, Fukuma K, Yamamoto H, Washida K, Kimura S, Kada A, Miyata S, Miyata T, Nagatsuka K
- Journal Title
  
  Genes (Basel)
  
  Volume: 12 Issue: 10 Pages: 1537-1537
- DOI
  10.3390/genes12101537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] 遺伝性血栓性素因患者の妊娠分娩管理に関する診療の手引きQ&A2021
- Author(s)
  小林隆夫、森下英理子、津田博子、根木玲子、小嶋哲人、大賀正一、落合正行、安達知子、宮田敏行
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 30(2) Pages: 5-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09277
[Journal Article] Derlin-3 is required for changes in ERAD complex formation under ER stress2020
- Author(s)
  Eura Y, Miyata T, Kokame K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 17 Pages: 6146-6146
- DOI
  10.3390/ijms21176146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] Predictive value of protein S-specific activity and ELISA testing in patients with the protein S K196E mutation.2020
- Author(s)
  Miyoshi T, Maruyama K, Oku H, Asahara S, Hanada H, Neki R, Yoshimatsu J, Kokame K, Miyata T.
- Journal Title
  
  Thrombosis Research
  
  Volume: 185 Pages: 1-4
- DOI
  10.1016/j.thromres.2019.10.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17J11206, KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-17K16316, KAKENHI-PROJECT-18K09277
[Journal Article] Success and limitations of plasma treatment in pregnant women with congenital thrombotic thrombocytopenic purpura2020
- Author(s)
  Sakai Kazuya、Fujimura Yoshihiro、Nagata Yasuyuki、Higasa Satoshi、Moriyama Masato、Isonishi Ayami、Konno Mutsuko、Kajiwara Michiko、Ogawa Yoshiyuki、Kaburagi Shigehiko、Hara Tomoko、Kokame Koichi、Miyata Toshiyuki、Hatakeyama Kinta、Matsumoto Masanori
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 18 Issue: 11 Pages: 2929-2941
- DOI
  10.1111/jth.15064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] Low-Dose Activated Protein C Suppresses the Development of Cerebral Infarction and Neurological Deficits in Mice2020
- Author(s)
  Yamato Keiko、Nakajo Yukako、Yamamoto-Imoto Hitomi、Kokame Koichi、Miyata Toshiyuki、Takahashi Jun C、Kataoka Hiroharu、Yanamoto Hiroji
- Journal Title
  
  Neurosurgery Open
  
  Volume: 1 Issue: 4 Pages: 1-12
- DOI
  10.1093/neuopn/okaa014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] 遺伝性血栓性素因患者の妊娠分娩管理に関する診療の手引きQ&A2020
- Author(s)
  厚生労働科学研究費補助金難治性疾患政策研究事業血液凝固異常症等に関する研究特発性血栓症研究グループ、小林隆夫、森下英理子、津田博子、根木玲子、小嶋哲人、大賀正一、落合正行、安達知子、宮田敏行
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 30 Pages: 5-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] 凝固系と血小板の活性化への補体の関わり2020
- Author(s)
  宮田敏行
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 10 Pages: 258-262
- Data Source
  KAKENHI-PROJECT-19K08875
[Journal Article] Knock‐in mice bearing constitutively active αIIb(R990W) mutation develop macrothrombocytopenia with severe platelet dysfunction2019
- Author(s)
  Akuta Keigo、Kiyomizu Kazunobu、Kashiwagi Hirokazu、Kunishima Shinji、Nishiura Nobuko、Banno Fumiaki、Kokame Koichi、Kato Hisashi、Kanakura Yuzuru、Miyata Toshiyuki、Tomiyama Yoshiaki
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 18 Issue: 2 Pages: 497-509
- DOI
  10.1111/jth.14678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-19K08813, KAKENHI-PROJECT-19K08875, KAKENHI-PROJECT-19K11725
[Journal Article] A less-intensive anticoagulation protocol of therapeutic unfractionated heparin administration for pregnant patients.2019
- Author(s)
  Neki R, Mitsuguro M, Okamoto A, Ida K, Miyoshi T, Kamiya C, Iwanaga N, Miyata T, Yoshimatsu J.
- Journal Title
  
  Int J Hematol.
  
  Volume: 110(5) Issue: 5 Pages: 550-558
- DOI
  10.1007/s12185-019-02712-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09277, KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17K16316
[Journal Article] Early Identification of Protein S K196E Mutation in a Patient With Cerebral Venous Thrombosis: A Case Report2019
- Author(s)
  Fujita Kyohei、Sonoda Kazutaka、Miyata Toshiyuki、Ihara Masafumi、Toyoda Kazunori、Koga Masatoshi
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 28 Issue: 1 Pages: 232-233
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.09.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Effects of low-dose combined oral contraceptives and protein S K196E mutation on anticoagulation factors: a prospective observational study2019
- Author(s)
  Takekazu Miyoshi, Hisato Oku, Saiko Asahara, Akira Okamoto, Koichi Kokame, Michikazu Nakai, Kunihiro Nishimura, Fumiyuki Otsuka, Aya Higashiyama, Jun Yoshimatsu, Toshiyuki Miyata
- Journal Title
  
  International Journal of Hematology
  
  Volume: 印刷中 Issue: 6 Pages: 641-649
- DOI
  10.1007/s12185-019-02633-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17K16316
[Journal Article] 病態生理と病理補体反応2018
- Author(s)
  宮田敏行、中村敏子
- Journal Title
  
  救急・集中治療
  
  Volume: 30 Pages: 93-98
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] 補体と血栓2018
- Author(s)
  宮田敏行、井上徳光
- Journal Title
  
  補体
  
  Volume: 55 Pages: 13-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] 遺伝性血栓性素因妊婦の周産期管理について2018
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 19 Pages: 385-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke2018
- Author(s)
  Wada Shinichi、Toyoda Kazunori、Sato Shoichiro、Matsuki Takayuki、Okata Takuya、Kumamoto Masaya、Tagawa Naoki、Inoue Manabu、Okamoto Akira、Ihara Masafumi、Kitazono Takanari、Miyata Toshiyuki、Koga Masatoshi
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 11 Pages: 2872-2879
- DOI
  10.1253/circj.CJ-18-0506
- NAID
  40021697278
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-10-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04308, KAKENHI-PROJECT-16K09834
[Journal Article] Clinical manifestation of patients with atypical hemolytic uremic syndrome with the C3 p.I1157T variation in the Kinki region of Japan.2018
- Author(s)
  Matsumoto T, Toyoda H, Amano K, Hirayama M, Ishikawa E, Fujimoto M, Ito M, Ohishi K, Katayama N, Yoshida Y, Matsumoto M, Kawamura N, Ikejiri M, Kawakami K, Miyata T, Wada H
- Journal Title
  
  Clin Appl Thromb Hemost
  
  Volume: 24 Issue: 8 Pages: 1301-1307
- DOI
  10.1177/1076029618771750
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-18K07817, KAKENHI-PROJECT-17K16073, KAKENHI-PROJECT-15K08645, KAKENHI-PROJECT-16K09834
[Journal Article] Clinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome2018
- Author(s)
  Fujisawa Madoka、Kato Hideki、Yoshida Yoko、Usui Tomoko、Takata Munenori、Fujimoto Mika、Wada Hideo、Uchida Yumiko、Kokame Koichi、Matsumoto Masanori、Fujimura Yoshihiro、Miyata Toshiyuki、Nangaku Masaomi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 印刷中 Issue: 5 Pages: 1088-1099
- DOI
  10.1007/s10157-018-1549-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-17K16073, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
[Journal Article] von Willebrand factor aggravates hepatic ischemia-reperfusion injury by promoting neutrophil recruitment in mice2018
- Author(s)
  Urisono Y, Sakata A, Matsui H, Kasuda S, Ono S, Nishio K, Sho M, Okuchi K, Akiyama M, Miyata T, Nishimura S, Sugimoto M
- Journal Title
  
  Thromb Haemost
  
  Volume: 118 Issue: 04 Pages: 700-708
- DOI
  10.1055/s-0038-1636529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K10034, KAKENHI-PROJECT-15K10990, KAKENHI-PROJECT-16K08515
[Journal Article] 凝固系の活性化と制御機構2018
- Author(s)
  宮田敏行、豊田一則
- Journal Title
  
  日本臨床
  
  Volume: 76 Pages: 1523-1528
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Eculizumabが奏効した高齢発症非典型溶血性尿毒症症候群2018
- Author(s)
  深澤千咲、大石沙織、熊谷拓磨、輿石めぐみ、末木侑希、中嶌圭、三森徹、吉田瑶子、加藤秀樹、南学正臣、宮田敏行、桐戸敬太
- Journal Title
  
  臨床血液
  
  Volume: 59 Pages: 182-186
- NAID
  130006441942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Clinical manifestation of atypical hemolytic uremic syndrome patients with the C3 p.I1157T variation in the Kinki region of Japan2018
- Author(s)
  Matsumoto T, Toyoda, H, Amano K, Hirayama M, Ishikawa E, FujimotoM, Ito M, Ohishi, K, Katayama N, Yoshida Y, Matsumoto M, Kawamura N, Ikejiri M, Kawakami K, Miyata T, Wada H
- Journal Title
  
  Clin Appl Thromb Hemost
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Functional splicing analysis in an infantile case of atypical hemolytic uremic syndrome caused by digenic mutations in C3 and MCP genes2018
- Author(s)
  Yamamura Tomohiko、Nozu Kandai、Ueda Hiroaki、Fujimaru Rika、Hisatomi Ryutaro、Yoshida Yoko、Kato Hideki、Nangaku Masaomi、Miyata Toshiyuki、Sawai Toshihiro、Minamikawa Shogo、Kaito Hiroshi、Matsuo Masafumi、Iijima Kazumoto
- Journal Title
  
  Journal of Human Genetics
  
  Volume: Epub ahead of print Issue: 6 Pages: 755-759
- DOI
  10.1038/s10038-018-0436-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16073, KAKENHI-PROJECT-15K09691, KAKENHI-PROJECT-16K09834
[Journal Article] Protein S K196E mutation reduces its cofactor activity for APC but not for TFPI2018
- Author(s)
  Keiko Maruyama, Masashi Akiyama, Toshiyuki Miyata, Koichi Kokame
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis
  
  Volume: 2 Issue: 4 Pages: 751-756
- DOI
  10.1002/rth2.12152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-17J11206, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-16K08515
[Journal Article] 遺伝性血栓性素因妊婦の周産期管理について2018
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 19 Pages: 385-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09277
[Journal Article] Major bleeding in a patient with warfarin-hypersensitive and factor IX propeptide variant, p.Ala37Thr, who was treated with a direct oral anti-Xa inhibitor2018
- Author(s)
  Tamura Asako、Wada Hideo、Ikejiri Makoto、Miyata Toshiyuki、Habe Koji、Tomimoto Hidekazu
- Journal Title
  
  Annals of Hematology
  
  Volume: 98 Issue: 1 Pages: 209-210
- DOI
  10.1007/s00277-018-3398-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] 血栓性血小板減少性紫斑病 (TTP)診療ガイド20172017
- Author(s)
  松本雅則、藤村吉博、和田英夫、小亀浩市、宮川義隆、上田恭典、日笠聡、森木隆典、八木秀男、宮田敏行、村田満
- Journal Title
  
  臨床血液
  
  Volume: 58 Pages: 271-281
- NAID
  40021201622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions2017
- Author(s)
  Tashima Yuko、Banno Fumiaki、Kita Toshiyuki、Matsuda Yasuyuki、Yanamoto Hiroji、Miyata Toshiyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 7 Pages: e0180981-e0180981
- DOI
  10.1371/journal.pone.0180981
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-16K09835, KAKENHI-PROJECT-16K14696, KAKENHI-PROJECT-16K19045
[Journal Article] Thrombotic thrombocytopenic purpura2017
- Author(s)
  Kremer Hovinga Johanna A.、Coppo Paul、Lammle Bernhard、Moake Joel L.、Miyata Toshiyuki、Vanhoorelbeke Karen
- Journal Title
  
  Nature Reviews Disease Primers
  
  Volume: 3 Issue: 1 Pages: 17020-17020
- DOI
  10.1038/nrdp.2017.20
- NAID
  130004920625
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] Live imaging of extracellular signal-regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Foerster resonance energy transfer2017
- Author(s)
  Takuya Hiratsuka,Takeshi Sano,Hisashi Kato,Naoki Komatsu,Masamichi Imajo,Yuji Kamioka,Kenta Sumiyama,Fumiaki Banno,Toshiyuki Miyata,Michiyuki Matsuda
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 印刷中 Issue: 7 Pages: 1487-1499
- DOI
  10.1111/jth.13723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21109, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-16K09835, KAKENHI-PROJECT-16K21106
[Journal Article] 内因系凝固反応活性化機序と遺伝性血管性浮腫2017
- Author(s)
  宮田敏行、内田裕美子、武田壮一
- Journal Title
  
  補体
  
  Volume: 54 Pages: 4-22
- NAID
  40021426772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] IV.　動脈・静脈疾患の臨床研究動向　４．血栓性素因の遺伝要因2017
- Author(s)
  丸山慶子、宮田敏行
- Journal Title
  
  動脈・静脈の疾患（上）　最新の診断・治療動向
  
  Volume: 75 Pages: 277-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] 凝固制御因子の臨床化学2017
- Author(s)
  宮田敏行、岡本章
- Journal Title
  
  臨床化学
  
  Volume: 46 Pages: 113-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] 補体系と凝固系2017
- Author(s)
  宮田敏行、吉田亜佑美
- Journal Title
  
  腎と透析
  
  Volume: 83 Pages: 563-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09834
[Journal Article] For TTP group of Blood Coagulation Abnormalities Research Team, Research on Rare and Intractable Disease supported by Health, Labour, and Welfare Sciences Research Grants.: Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan.2017
- Author(s)
  Matsumoto M, Fujimura Y, Wada H, Kokame K, Miyakawa Y, Ueda Y, Higasa S, Moriki T, Yagi H, Miyata T, Murata M;
- Journal Title
  
  Int J Hematol
  
  Volume: 106 Issue: 1 Pages: 3-15
- DOI
  10.1007/s12185-017-2264-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08645, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-17K07358
[Journal Article] Genetic variations in complement factors in patients with congenital thrombotic thrombocytopenic purpura with renal insufficiency.2016
- Author(s)
  Fan X, Kremer Hovinga JA, Shirotani-Ikejima H, Eura Y, Hirai H, Honda S, Kokame K, Taleghani MM, von Krogh AS, Yoshida Y, Fujimura Y, Lammle B, Miyata T
- Journal Title
  
  Int J Hematol
  
  Volume: 103 Issue: 3 Pages: 283-291
- DOI
  10.1007/s12185-015-1933-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09463, KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-15K18510
[Journal Article] No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome2016
- Author(s)
  Miyata T, Uchida Y, Yoshida Y, Kato H, Matsumoto M, Kokame K, Fujimura Y, Nangaku M
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Issue: 2 Pages: 223-227
- DOI
  10.1007/s12185-016-2021-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
[Journal Article] Disease Recurrence After Early Discontinuation of Eculizumab in a Patient With Atypical Hemolytic Uremic Syndrome With Complement C3 I1157T Mutation.2016
- Author(s)
  Toyoda, H., Wada, H., Miyata, T., Amano, K., Kihira, K., Iwamoto, S., Hirayama, M., Komada, Y.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 38 Issue: 3 Pages: e137-e139
- DOI
  10.1097/mph.0000000000000505
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461443, KAKENHI-PROJECT-15K08645, KAKENHI-PROJECT-15K09650, KAKENHI-PROJECT-16K09834
[Journal Article] Adverse pregnancy outcomes and congenital thrombophilia2016
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 27 Issue: 3 Pages: 339-348
- DOI
  10.2491/jjsth.27.339
- NAID
  130005157426
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462507, KAKENHI-PROJECT-16K09834
[Journal Article] Cardiovascular events occur independently of high on-aspirin platelet reactivity and residual COX-1 activity in stable cardiovascular patients2016
- Author(s)
  Nagatsuka K, Miyata S, Kada A, Wada H, et al
- Journal Title
  
  Thromb Haemost
  
  Volume: 116 Issue: 08 Pages: 356-368
- DOI
  10.1160/th15-11-0864
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08645, KAKENHI-PROJECT-16K09834
[Journal Article] Complete remission of thrombotic microangiopathy after treatment with eculizumab in a patient with non-Shiga toxin-associated bacterial enteritis: A case report.2016
- Author(s)
  Omura T, Watanabe E, Otsuka Y, Yoshida Y, Kato H, Nangaku M, Miyata T, Oda S.
- Journal Title
  
  Medicine
  
  Volume: 95 Issue: 27 Pages: e4104-e4104
- DOI
  10.1097/md.0000000000004104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
[Journal Article] Thrombophilia in East Asian countries: are there any genetic differences in these countries?2016
- Author(s)
  Miyata T, Maruyama K, Banno F, Neki R.
- Journal Title
  
  Thromb J.
  
  Volume: 14(Suppl 1):25 Issue: S1 Pages: 123-128
- DOI
  10.1186/s12959-016-0109-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462507, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-16K09835
[Journal Article] Influence of a rotational speed modulation system used with an implantable continuous-flow left ventricular assist device (EVAHEART) on von Willebrand factor dynamics2016
- Author(s)
  Noritsugu Naito, Toshihide Mizuno, Takashi Nishimura, Satoru Kishimoto, Yoshiaki Takewa, Yuka Eura, Koichi Kokame, Toshiyuki Miyata, Kazuma Date, Akihide Umeki, Masahiko Ando, Minoru Ono, and Eisuke Tatsumi
- Journal Title
  
  Artif. Organs
  
  Volume: 未定 Issue: 9 Pages: 877-883
- DOI
  10.1111/aor.12666
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-25560217, KAKENHI-PROJECT-25293294, KAKENHI-PROJECT-15K18510, KAKENHI-PROJECT-16K09834
[Journal Article] Influence of ADAMTS13 deficiency on venous thrombosis in mice2015
- Author(s)
  Tashima Y, Banno F, Akiyama M, Miyata T
- Journal Title
  
  Thromb Haemost
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] A Novel Quantitative Hemolytic Assay Coupled with Restriction Fragment Length Polymorphisms Analysis Enabled Early Diagnosis of Atypical Hemolytic Uremic Syndrome and Identified Unique Predisposing Mutations in Japan.2015
- Author(s)
  Yoshida Y, Miyata T, Matsumoto M, Shirotani-Ikejima H, Uchida Y, Ohyama Y, Kokubo T, Fujimura Y.
- Journal Title
  
  PLos One
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860685
[Journal Article] Exacerbated venous thromboembolism in mice carrying protein S K196E mutation2015
- Author(s)
  Fumiaki Banno, Toshiyuki Kita, Jose A. Fernandez, Hiroji Yanamoto, Yuko Tashima, Koichi Kokame, John H. Griffin, and Toshiyuki Miyata
- Journal Title
  
  Blood
  
  Volume: 126 Issue: 19 Pages: 2247-2253
- DOI
  10.1182/blood-2015-06-653162
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-25461465
[Journal Article] 先天性プロテインC欠乏症、先天性アンチトロンビン欠乏症合併妊娠2015
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本産婦人科新生児血液学会誌
  
  Volume: Vol.25 No.1 Pages: 17-24
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462507
[Journal Article] Familial C3 glomerulonephritis associated with mutations in the gene for complement factor B.2015
- Author(s)
  Imamura H, Konomoto T, Tanaka E, Hisano S, Yoshida Y, Fujimura Y, Miyata T, Nunoi H.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 30 Issue: 5 Pages: 862-864
- DOI
  10.1093/ndt/gfv054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25860873
[Journal Article] 先天性プロテインC欠乏症、先天性アンチトロンビン欠乏症と妊娠2015
- Author(s)
  根木玲子、宮田敏行
- Journal Title
  
  日本産婦人科・新生児血液学会学会誌
  
  Volume: 25 Pages: 55-62
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462507
[Journal Article] Influence of ADAMTS13 deficiency on venous thrombosis in mice2015
- Author(s)
  Tashima Y, Banno F, Akiyama M, Miyata T
- Journal Title
  
  Thromb Haemost
  
  Volume: 印刷中 Issue: 07 Pages: 206-207
- DOI
  10.1160/th14-08-0656
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670454, KAKENHI-PROJECT-25860801, KAKENHI-PROJECT-25461465
[Journal Article] Introduce My Article2015
- Author(s)
  坂野史明, 宮田敏行
- Journal Title
  
  臨床血液
  
  Volume: 56 Pages: 2358-2358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461465
[Journal Article] Effects of factor VIII levels on the APTT and anti-Xa activity under a therapeutic dose of heparin2015
- Author(s)
  Mitsuguro M, Okamoto A, Shironouchi Y, Sano M, Miyata S, Neki R, Araki T, Hamamoto T, Yoshimatsu J, Miyata T
- Journal Title
  
  Int J Hematol
  
  Volume: 101 Issue: 2 Pages: 119-125
- DOI
  10.1007/s12185-014-1702-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-26462507
[Journal Article] Familial C3 glomerulonephritis associated with mutations in the gene for complement factor B.2015
- Author(s)
  Imamura H, Konomoto T, Tanaka E, Hisano S, Yoshida Y, Fujimura Y, Miyata T, Nunoi H.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860685
[Journal Article] Eculizumab in the treatment of atypical hemolytic uremic syndrome in an infant leads to cessation of peritoneal dialysis and improvement of severe hypertension.2015
- Author(s)
  Ohta T, Urayama K, Tada Y, Furue T, Imai S, Matsubara K, Ono H, Sakano T, Jinno K, Yoshida Y, Miyata T, Fujimura Y.
- Journal Title
  
  Pediatr Nephrol.
  
  Volume: 30 Issue: 4 Pages: 603-608
- DOI
  10.1007/s00467-014-2975-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25860685
[Journal Article] 非典型HUSにおける補体異常とその解析2014
- Author(s)
  吉田瑶子、藤村吉博、宮田敏行
- Journal Title
  
  細胞
  
  Volume: 46 Pages: 7-10
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Contribution of ADAMTS13 to the better cell engraftment efficacy in mouse model of bone marrow transplantation2014
- Author(s)
  Matsui H, Takeda M, Soejima K, Matsunari Y, Kasuda S, Ono S, Nishio K, Shima M, Banno F, Miyata T, Sugimoto M
- Journal Title
  
  Haematologica
  
  Volume: 99 Issue: 10 Pages: 211-213
- DOI
  10.3324/haematol.2014.109512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461465, KAKENHI-PROJECT-25670454
[Journal Article] Candidate gene analysis using genomic quantitative PCR: identification of ADAMTS13 large deletions in two patients with Upshaw-Schulman syndrome.2014
- Author(s)
  Eura Y, Kokame K, Takafuta T, Tanaka R, Kobayashi H, Ishida F, Hisanaga S, Matsumoto M, Fujimura Y, Miyata T.
- Journal Title
  
  olecular Genetics & Genomic Medicine.
  
  Volume: 2 Issue: 3 Pages: 240-244
- DOI
  10.1002/mgg3.64
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-25461456
[Journal Article] 非典型HUSにおける補体異常とその解析2014
- Author(s)
  吉田瑶子、藤村吉博、宮田敏行
- Journal Title
  
  細胞　The cell
  
  Volume: 46 Pages: 7-10
- Data Source
  KAKENHI-PROJECT-25860685
[Journal Article] プロテインC/プロテインSの基礎2014
- Author(s)
  宮田敏行、水口　純、鈴木敦夫、小嶋哲人
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 25 Pages: 40-47
- NAID
  130003393337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Analysis of patients with atypical hemolytic uremic syndrome treated at the Mie University Hospital: Concentration of C3 p.I1157T mutation.2014
- Author(s)
  Matsumoto T, Fan X, Ishikawa E, Ito M, Amano K, Toyoda H, Komada Y, Ohishi K, Katayama N, Yoshida Y, Matsumoto M, Fujimura Y, Ikejiri M, Wada H, Miyata T.
- Journal Title
  
  Int J Hematol.
  
  Volume: 100 Issue: 5 Pages: 437-442
- DOI
  10.1007/s12185-014-1655-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25461413, KAKENHI-PROJECT-25461456, KAKENHI-PROJECT-25860685
[Journal Article] ターゲット領域の異常を見逃さないゲノム定量PCR法の確立：ダイレクトシークエンシング法の弱点を補う解析方法として2014
- Author(s)
  樋口(江浦)由佳、小亀浩市、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 25 Pages: 615-618
- NAID
  130004700440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Postoperative atypical hemolytic uremic syndrome associated with complement c3 mutation.2014
- Author(s)
  Matsukuma E, Imamura A, Iwata , Takeuchi T, Yoshida Y, Fujimura Y, Fan X, Miyata T, Kuwahara T.
- Journal Title
  
  Case Rep Nephrol.
  
  Volume: 2014 Pages: 784943-784943
- DOI
  10.1155/2014/784943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25860685
[Journal Article] 日本人における先天性血栓性素因　-欧米との比較-2014
- Author(s)
  宮田敏行、丸山慶子
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 908-916
- NAID
  130004688004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Contribution of ADAMTS13 to the better cell engraftment efficacy in mouse model of bone marrow transplantation2014
- Author(s)
  Matsui H, Takeda M, Soejima K, Matsunari Y, Kasuda S, Ono S, Nishio K, Shima M, Banno F, Miyata T, Sugimoto M
- Journal Title
  
  Haematologica
  
  Volume: 99 Pages: 211-213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] ファーマコゲノミクス2014
- Author(s)
  田中智貴、長束一行、宮田敏行
- Journal Title
  
  分子脳血管病
  
  Volume: 13 Pages: 42-46
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Nonsynonymous mutations in three anticoagulant genes in Japanese patients with adverse pregnancy outcomes.2014
- Author(s)
  Neki R, Miyata T, Fujita T, Kokame K, Fujita D, Isaka S, Ikeda T, Yoshimatsu J
- Journal Title
  
  Thromb Res
  
  Volume: 133 Issue: 5 Pages: 914-918
- DOI
  10.1016/j.thromres.2014.02.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-26462507
[Journal Article] Dysfunction of protein C anticoagulant system, main genetic risk factor for venous thromboembolism in Northeast Asians.2014
- Author(s)
  Yin T, Miyata T
- Journal Title
  
  J Thromb Thrombolysis
  
  Volume: 37 Issue: 1 Pages: 56-65
- DOI
  10.1007/s11239-013-1005-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 補体反応2014
- Author(s)
  宮田敏行、中村敏子
- Journal Title
  
  救急・集中治療
  
  Volume: 26 Pages: 668-673
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 血栓性血小板減少性紫斑病2014
- Author(s)
  藤村吉博、松本雅則、石西綾美、八木秀男、小亀浩市、宮田敏行
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 93-104
- NAID
  130004920625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 先天性ADAMTS13欠損症2013
- Author(s)
  宮田敏行、小亀浩市、小久保喜弘
- Journal Title
  
  臨床検査
  
  Volume: 57 Pages: 556-561
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 抗CFH抗体陽性およびCFHR1遺伝子欠損を伴うDEAP-HUSの1例2013
- Author(s)
  岡政史、大塚泰史、稲田由紀子、佐藤忠司、吉田瑶子、藤村吉博、Xinping Fan、宮田敏行、濱崎雄平
- Journal Title
  
  日本小児腎臓病学会雑誌
  
  Volume: 26 Pages: 109-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860685
[Journal Article] Long term follow up of congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndorome) on hemodialysis for 19 years: a case report2013
- Author(s)
  Mise K, Ubara Y, Matsumoto M, Sumida K, Hiramatsu R, Hasegawa E, Yamanouchi M, Hayami N, Suwabe T, Hoshino J, Sawa N, Ohashi K, Kokame K, Miyata T, Fujimura Y, Takaichi K.
- Journal Title
  
  BMC Nephrol.
  
  Volume: 14 Issue: 1 Pages: 156-156
- DOI
  10.1186/1471-2369-14-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25440060, KAKENHI-PROJECT-25461456
[Journal Article] 遺伝子改変血栓モデル：ADAMTS13遺伝子欠損マウスを中心に2013
- Author(s)
  坂野史明、宮田敏行、藤岡政行、杉本充彦
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3 Pages: 36-43
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Budd-Chiari Syndrome with multiple thrombi due to a familial Arg42Ser mutation in the protein C gene.2013
- Author(s)
  Muratsu J, Morishima A, Mizoguchi K, Ataka K, Yamamoto H, Fan X, Miyata T, Sakaguchi K
- Journal Title
  
  Case Reports in Medicine
  
  Volume: 2013 Pages: 270419-270419
- DOI
  10.1155/2013/270419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 抗CFH抗体陽性およびCFHR1遺伝子欠失を伴うDEAP-HUSの１例2013
- Author(s)
  岡　政史、大塚泰史、稲田由紀子、佐藤忠司、吉田瑶子、藤村吉博、Fan Xinping、宮田敏行、濱崎雄平
- Journal Title
  
  日本小児腎臓病学会雑誌
  
  Volume: 26 Pages: 109-115
- NAID
  130004495423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 非典型溶血性尿毒症症候群（aHUS)2013
- Author(s)
  藤村吉博、吉田瑶子、範新萍、宮田敏行
- Journal Title
  
  臨床血液
  
  Volume: 54 Pages: 351-360
- NAID
  10031196335
- Data Source
  KAKENHI-PROJECT-25860685
[Journal Article] ADAMTS13 activity and genetic mutations in Japanese subjects.2013
- Author(s)
  Toshiyuki Miyata, Koichi Kokame, Masanori Matsumoto, and Yoshihiro Fujimura.
- Journal Title
  
  Haemostaselolgie
  
  Volume: 33 Issue: 02 Pages: 131-137
- DOI
  10.5482/hamo-12-11-0017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25440060
[Journal Article] 遺伝子改変血栓モデル：ADAMTS13遺伝子欠損マウスを中心に2013
- Author(s)
  坂野史明, 宮田敏行, 藤岡政行, 杉本充彦
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3 Pages: 132-139
- Data Source
  KAKENHI-PROJECT-25461465
[Journal Article] Atypical HUSにおける補体制御異常症診断システムの構築と腎移植2013
- Author(s)
  芦田　明、吉田瑶子、範　新萍、松本雅則、服部元史、宮田敏行、藤村吉博
- Journal Title
  
  日本臨床腎移植学会雑誌
  
  Volume: 1 Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Analysis of genetic and predisposing factors in Japanese patients with atypical hemolytic uremic syndrome.2013
- Author(s)
  Fan X, Yoshida Y, Honda S, et al. (Matsumoto M ４番目)
- Journal Title
  
  Mol Immunol.
  
  Volume: 54 Issue: 2 Pages: 238-246
- DOI
  10.1016/j.molimm.2012.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591069, KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25461456, KAKENHI-PROJECT-25860685
[Journal Article] Crystal structure and enzymatic activity of an ADAMTS13 mutant with the East Asian-specific P475S polymorphism.2013
- Author(s)
  Masashi Akiyama, Daisuke Nakayama, Soichi Takeda, Koichi Kokame, Junichi Takagi, and Toshiyuki Miyata.
- Journal Title
  
  J. Thromb. Haemost.
  
  Volume: (In press) Issue: 7 Pages: 1399-1406
- DOI
  10.1111/jth.12279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-23570155, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-25440060
[Journal Article] The Integrin-Linked Kinase-PINCH-Parvin Complex Supports Integrin αIIbβ3 Activation2013
- Author(s)
  Hond S, Shirotani-Ikejima H, Tadokoro S, Tomiyama Y, Miyata T
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 12 Pages: 1-13
- DOI
  10.1371/journal.pone.0085498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591430, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-24591422
[Journal Article] 先天性血栓性素因2013
- Author(s)
  宮田敏行、森下英理子
- Journal Title
  
  血栓と循環
  
  Volume: 21 Pages: 6-11
- NAID
  10005477772
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] ADAMTS13とvon Willebrand因子2013
- Author(s)
  宮田敏行, 松本雅則
- Journal Title
  
  カレントテラピー
  
  Volume: 31 Pages: 94-94
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Protein S K196E mutation, a genetic risk factor venous thromboembolism, is limited to Japanese.2013
- Author(s)
  Liu W, Yin T, Okuda H, Harada KH, Li Y, Xu B, Yang J, Wang H, Fan X, Koizumi A, Miyata T
- Journal Title
  
  Thromb Res
  
  Volume: 132 Pages: 314-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 東アジア人特有のP475S変異を持つADAMTS13の立体構造と機能解析2013
- Author(s)
  秋山正志、武田壮一、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 24 Pages: 613-618
- NAID
  130003393326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 遺伝子改変血栓モデル：ADAMTS13遺伝子欠損マウスを中心に2013
- Author(s)
  坂野史明、宮田敏行、藤岡政行、杉本充彦
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3 Pages: 36-43
- Data Source
  KAKENHI-PROJECT-25670454
[Journal Article] 非典型溶血性尿毒症症候群（aHUS）2013
- Author(s)
  藤村吉博、吉田瑶子、範　新萍、宮田敏行
- Journal Title
  
  臨床血液
  
  Volume: 54 Pages: 351-360
- NAID
  10031196335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] Large infarct and high mortality by cerebral ischemia in mice carrying the factor V Leiden mutation2012
- Author(s)
  Kita T, Banno F, Yanamoto H, Nakajo Y, Iihara K, Miyata T
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10 Issue: 7 Pages: 1453-1455
- DOI
  10.1111/j.1538-7836.2012.04776.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23659494, KAKENHI-PROJECT-24390250
[Journal Article] A second hit for TMA.2012
- Author(s)
  Miyata T, Fan X
- Journal Title
  
  Blood
  
  Volume: 120 Issue: 6 Pages: 1152-1154
- DOI
  10.1182/blood-2012-06-433235
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] マウス急性心筋梗塞モデルにおけるADAMTS13の心筋保護作用2012
- Author(s)
  杉本充彦、土井政明、松井英人、宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 第23巻 Pages: 590-593
- NAID
  130003367332
- URL
  https://www.jstage.jst.go.jp/article/jjsth/23/6/23_590/_article/-char/ja/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659494
[Journal Article] ADAMTS13 gene deletion enhances plasma high-mobility group boxl elevation and neuroinflammation in brain ischemia-reperfusion injury.2012
- Author(s)
  Fujioka M, Nakano T, Hayakawa K, Irie K, Akitake Y, Sakamoto Y, Mishima K, Muroi C, Yonekawa Y, Banno F, Kokame K, Miyata T, Nishio K, Okuchi K, Iwasaki K, Fujiwara M, Siesjo
- Journal Title
  
  Neurol Sci
  
  Volume: 33 Pages: 1107-1115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659494
[Journal Article] More on : racial differences in venous thromboembolism2012
- Author(s)
  T. Miyata, N. Hamasaki, H. Wada, T. Kojima
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10 Issue: 2 Pages: 319-320
- DOI
  10.1111/j.1538-7836.2011.04578.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] 血栓の病理と病態2012
- Author(s)
  宮田敏行,樋口由佳
- Journal Title
  
  Vascular Lab
  
  Volume: 9 Pages: 70-73
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] ADAMTS13研究の最先端2012
- Author(s)
  宮田敏行, 他5名
- Journal Title
  
  臨床血液
  
  Volume: 53 Pages: 672-679
- NAID
  10030990234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] von Willebrand因子とADAMTS132012
- Author(s)
  宮田敏行,松本雅則
- Journal Title
  
  内科
  
  Volume: 110 Pages: 87-90
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] 凝固XI因子の構造と機能2012
- Author(s)
  西村仁, 平井秀憲, 宮田敏行
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 23 Pages: 594-598
- NAID
  130003367333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390250
[Journal Article] ADAMTS13 safeguards the myocardium in a mouse model of acute myocardial infarction.2012
- Author(s)
  Masaaki Doi, Hideto Matsui, Yukiji Takeda, Yoshihiko Saito, Maiko Takeda, Yasunori Matsunari, Kenji Nishio, Midori Shima, Fumiaki Banno, Masashi Akiyama, Koichi Kokame, Toshiyuki Miyata, and Mitsuhiko Sugimoto.
- Journal Title
  
  Thromb. Haemost.
  
  Volume: 108 Issue: 12 Pages: 1236-1238
- DOI
  10.1160/th12-09-0674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23570155, KAKENHI-PROJECT-23659494, KAKENHI-PROJECT-24390250, KAKENHI-PROJECT-24592744
[Journal Article] Pharmacogenomics of clopidogrel : Evidence and perspectives (review)2011
- Author(s)
  T.Yin, T.Miyata
- Journal Title
  
  Thromb Res
  
  Volume: 128 Issue: 4 Pages: 307-316
- DOI
  10.1016/j.thromres.2011.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] von Willebrand factor-to-ADAMTS13 ratio increases with age in a Japanese population2011
- Author(s)
  K. Kokame, T. Sakata, Y. Kokubo, T. Miyata
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9 Pages: 1426-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Genetic analysis of patients with deep vein thrombosis during pregnancy and postpartum2011
- Author(s)
  R. Neki, T. Fujita, K. Kokame, I. Nakanishi, M. Waguri, Y. Imayoshi, N. Suehara, T. Ikeda, T. Miyata
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Issue: 2 Pages: 150-155
- DOI
  10.1007/s12185-011-0902-z
- NAID
  10029537014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-22570151
[Journal Article] Polymorphisms and mutations of ADAMTS13 in the Japanese population and estimation of the number of patients with Upshaw-Schulman syndrome2011
- Author(s)
  K. Kokame, Y. Kokubo, T. Miyata
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9 Issue: 8 Pages: 1654-1656
- DOI
  10.1111/j.1538-7836.2011.04399.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-22570151
[Journal Article] In vivo imaging analysis of the interaction between unusually large von Willebrand factor multimers and platelets on the surface of vascular wall2011
- Author(s)
  Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Brzoska T, Tanaka A, Banno F, Miyata T, Urano T
- Journal Title
  
  Pflugers Arch
  
  Volume: 461(6) Issue: 6 Pages: 623-33
- DOI
  10.1007/s00424-011-0958-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23659494
[Journal Article] 日本人の血栓性素因、特にプロテインS欠損症を中心に2011
- Author(s)
  宮田敏行
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 20 Pages: 75-82
- NAID
  10029377825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] ADAMTS13 gene deletion aggravates ischemic brain damage : a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion2010
- Author(s)
  M. Fujioka, K. Hayakawa, K. Mishima, A. Kunizawa, K. Irie, S. Higuchi, T. Nakano, C. Muroi, H. Fukushima, M. Sugimoto, F. Banno, K. Kokame, T. Miyata, M. Fujiwara, K. Okuchi, K. Nishio
- Journal Title
  
  Blood
  
  Volume: 15 Issue: 8 Pages: 1650-1653
- DOI
  10.1182/blood-2009-06-230110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-22790923
[Journal Article] ADAMTS13 gene deletion aggravates ischemic brain damage : a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion.2010
- Author(s)
  M.Fujioka, K.Hayakawa, K.Mishima, A.Kunizawa, K.Irie, S.Higuchi, T.Nakano, C.Muroi, H.Fukushima, M.Sugimoto, F.Banno, K.Kokame, T.Miyata, M.Fujiwara, K.Okuchi, K.Nishio
- Journal Title
  
  Blood 115
  
  Pages: 1650-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article]2010
- Author(s)
  宮田敏行
- Journal Title
  
  Annual Review血液2010(中外医学社)
  
  Pages: 196-201
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Usefulness of antithrombin deficiency phenotypes for risk assessment of venous thromboembolism : type I deficiency as a strong risk factor for venous thromboembolism2010
- Author(s)
  M. Mitsuguro, T. Sakata, A. Okamoto, S. Kameda, Y. Kokubo, Y. Tsutsumi, M. Sano, T. Miyata
- Journal Title
  
  Int J Hematol
  
  Volume: 92 Issue: 3 Pages: 468-473
- DOI
  10.1007/s12185-010-0687-5
- NAID
  10027673474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] The function of ADAMTS13 in thrombogenesis in vivo : insights from mutant mice2010
- Author(s)
  F. Banno, A. K. Chauhan, T. Miyata
- Journal Title
  
  Int J Hematol
  
  Volume: 91 Issue: 1 Pages: 30-35
- DOI
  10.1007/s12185-009-0477-0
- NAID
  10026110458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-22790923
[Journal Article] Integrin-linked kinase associated with integrin activation2009
- Author(s)
  S. Honda, H. Shirotani-Ikejima, S. Tadokoro, Y. Maeda, T. Kinoshita, Y. Tomiyama, T. Miyata
- Journal Title
  
  Blood
  
  Volume: 113 Issue: 21 Pages: 5304-5313
- DOI
  10.1182/blood-2008-07-169136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-21591242
[Journal Article] 日本人静脈血栓塞栓症の遺伝的背景:プロテインSK196E変異の意義2009
- Author(s)
  宮田敏行
- Journal Title
  
  循環器病研究の進歩 30
  
  Pages: 70-76
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor2009
- Author(s)
  M. Akiyama, S. Takeda, K. Kokame, J. Takagi, T. Miyata
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106 Issue: 46 Pages: 19274-19279
- DOI
  10.1073/pnas.0909755106
- NAID
  10026400518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.2009
- Author(s)
  F.Banno, AK.Chauhan, K.Kokame, J.Yang, S.Miyata, DD.Wagner, T.Miyata
- Journal Title
  
  Blood 113
  
  Pages: 5323-5329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Integrin-linked kinase associated with integrin activation.2009
- Author(s)
  S.Honda, H.Shirotani-Ikejima, S.Tadokoro, Y.Maeda, T.Kinoshita, Y.Tomiyama, T.Miyata
- Journal Title
  
  Blood 113
  
  Pages: 5304-5313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation2009
- Author(s)
  F. Banno, AK. Chauhan, K. Kokame, J. Yang, S. Miyata, DD. Wagner, T. Miyata
- Journal Title
  
  Blood
  
  Volume: 113 Pages: 5323-5329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] 先天性血栓性素因の遺伝子解析2009
- Author(s)
  宮田敏行
- Journal Title
  
  臨床検査 53
  
  Pages: 1123-1128
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] 日本人の血栓性素因2009
- Author(s)
  宮田敏行
- Journal Title
  
  臨床血液 50
  
  Pages: 381-388
- NAID
  10026710476
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von willebrand factor.2009
- Author(s)
  M.Akiyama, S.Takeda, K.Kokame, J.Takagi, T.Miyata
- Journal Title
  
  Proc Natl Acad Sci 106
  
  Pages: 19274-19279
- NAID
  10026400518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis2009
- Author(s)
  T. Miyata, Y. Sato, J. Ishikawa, H. Okada, S. Takeshita, T. Sakata, K. Kokame, R. Kimura, S. Honda, T. Kawasaki, E. Suehisa, H. Tsuji, S. Madoiwa, Y. Sakata, T. Kojima, M. Murata, Y. Ikeda
- Journal Title
  
  Thromb Res
  
  Volume: 124 Issue: 1 Pages: 14-18
- DOI
  10.1016/j.thromres.2008.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis2009
- Author(s)
  Miyata T
- Journal Title
  
  Thromb Res (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] 血栓症とその予防薬に対する遺伝子のかかわり2009
- Author(s)
  宮田敏行
- Journal Title
  
  心臓 41
  
  Pages: 195-203
- NAID
  130003376869
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] 凝固制御因子欠損症、特にプロテインSを中心に2008
- Author(s)
  宮田敏行
- Journal Title
  
  BRAIN and NERVE 60
  
  Pages: 1285-1293
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] Inherited and de novo mutations of ADAMTS13 in a patient with Upshaw-Schulman syndrome.2008
- Author(s)
  K. Kokame, Y. Aoyama, M. Matsumoto, Y. Fujimura, T. Miyata
- Journal Title
  
  J Thromb Haemost 6
  
  Pages: 213-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] 大規模臨床試験主要薬剤の大規模臨床試験抗血小板薬アスピリンの二次予防2008
- Author(s)
  宮田敏行
- Journal Title
  
  日本臨牀 66
  
  Pages: 372-375
- Data Source
  KAKENHI-PROJECT-20390278
[Journal Article] ADAMTS13 assays and ADAMTS13-deficient mice.2007
- Author(s)
  Toshiyuki Miyata
- Journal Title
  
  Curr.Opin.Hematol. 14(3)
  
  Pages: 277-283
- Data Source
  KAKENHI-PROJECT-17570126
[Journal Article] Genotypes of vitamin K epoxide reductase,γ-glutamyl carboxylase,andcytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.2007
- Author(s)
  Kimura R, , Miyashita K, Kokubo Y, Akaiwa Y, Ryoichi O, Nagatsuka K, Otsuki T, Okayama A, Minematsu K, Naritomi H, Honda S, Tomoike H, Miyata T
- Journal Title
  
  Thromb Res 120
  
  Pages: 181-186
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Genotypes of vitamin K epoxide reductase, γ-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.2007
- Author(s)
  Kimura R, Miyashita K, Kokubo Y, Akaiwa Y, Ryoichi O, Nagatsuka K, Otsuki T, Okayama A, Minematsu K, Naritomi H, Honda S, Tomoike H, Miyata T
- Journal Title
  
  Thromb Res 120
  
  Pages: 181-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] ADAMTS13 assays and ADAMTS13-dificient mice.2007
- Author(s)
  T.Miyata, K. Kokame, F. Banno, Y. Shin, M. Akiyama
- Journal Title
  
  Curr Opin Hematol 14-3
  
  Pages: 277-283
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency.2007
- Author(s)
  Yin T, Takeshita S, Sato Y, Sakata T, Shin Y, Honda S, Kawasaki T, Tsuji H, Kojima T, Madoiwa S, Sakata Y, Murata M, Ikeda Y, Miyata T
- Journal Title
  
  Thromb Haemost 98
  
  Pages: 783-789
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency.2007
- Author(s)
  Yin T, Takeshita S, Sato Y, Sakata T, Shin Y, Honda S, Kawasaki T, Tsuji H, Kojima T, Madoiwa S, Sakata Y, Murata M, Ikeda Y, Miyata T
- Journal Title
  
  Thromb Haemost 98-4
  
  Pages: 783-789
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] ADAMTS13 assays and ADAMTS13-deficient mice2007
- Author(s)
  Toshiyuki Miyata
- Journal Title
  
  Curr. Opin. Hematol. 14(3)
  
  Pages: 277-283
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570126
[Journal Article] Adiponectin acts as an endogenous antithrombotic factor2006
- Author(s)
  Kato H, Kashiwagi H, Shiraga M, Tadokoro S, Kamae T, Ujiie H, Honda S, Miyata S, Ijiri Y, Yamamoto J, Maeda N, Funahashi T, Kurata Y, Shimomura I, Tomiyama Y, Kanakura Y
- Journal Title
  
  Arterioscler Thromb Vasc Biol 26・1
  
  Pages: 224-230
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Genotypes of vitamin K epoxide reductase,gammma-glutamyl carboxylase,and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.2006
- Author(s)
  Kimura R, Miyashita K, KokuboY, Akaiwa Y, Otsubo R, Nagatsuka K, Otsuki T, Okayama A, Minematsu K, NaritomiH, Honda S, Tomiike H, Miyata T
- Journal Title
  
  Thromb Res Epub
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Polymorphisms in vitamin K-dependent γ-carboxylation-related genes influence interindividual variability in plasma protein C and protein S activities in general population.2006
- Author(s)
  Kimura R, Kokubo Y, Miyashita K, Otsubo R, Nagatsuka K, Otsuki T, Sakata T, Nagura J, Okayama A, Minematsu K, Naritomi H, Honda S, Sato K, Tomoike H, Miyata T
- Journal Title
  
  Int J Hematol 84・5
  
  Pages: 387-397
- NAID
  10018670791
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Novel compound heterozygote mutations (H234Q/R1206X) of the ADAMTS13 gene in an adult patient with Upshaw-Schulman syndrome showing predominant episodes of repeated acute renal failure.2006
- Author(s)
  Shibagaki Y, Matsumoto M, Kokame K, Ohba S, Miyata T, Fujimura Y, Fujita T
- Journal Title
  
  Nephrol Dial Transplant 21
  
  Pages: 1289-1292
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Protein S-K196E mutation as a genetic risk factor for deep vein thrombosis in Japanese patients.2006
- Author(s)
  Kimura R, Honda S, Kawasaki T, Tsuji H, Madoiwa S, Sakata Y, Kojima T, Murata M, Nishigami K, Chiku M, Hayashi T, Kokubo Y, Okayama A, Tomoike H, Ikeda Y, Miyata T
- Journal Title
  
  Blood 107
  
  Pages: 1737-1738
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Genetic risk factors for deep vein thrombosis among Japanese : importance of protein S K196E mutation.2006
- Author(s)
  Miyata T, Kimura R, Kokubo Y, Sakata T
- Journal Title
  
  Int J Hematol 83
  
  Pages: 217-223
- NAID
  10017421942
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura.2006
- Author(s)
  Banno F, Kokame K, Okuda T, Honda S, Miyata S, Kato h, Tomiyama Y, Mjyata T
- Journal Title
  
  Blood 107・8
  
  Pages: 3161-3166
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Protein S-K196E mutation as a genetic risk factor for deep vein thrombosis in Japanese patients.2006
- Author(s)
  Kimura R, Honda S, Kawasaki T, Tsuji H, MadoiwaT S, Sakata Y, Kojima T, Murata M, Nishigami K, Chiku M, Hayashi T, Kokubo Y, Okayama A, Tomoike H, Ikeda Y, Miyata T
- Journal Title
  
  Blood 107・4
  
  Pages: 1737-1738
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura.2006
- Author(s)
  F Banno, K Kokame, T Okuda, S Honda, S Miyata, H Kato,Y Tomiyama, T Miyata
- Journal Title
  
  Blood 107-8
  
  Pages: 3161-3166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Complete dificiency in ADAMTS13 is prothrombotic,but it alone is not sufficient to cause thrombotic thrombocytopenic purpura.2006
- Author(s)
  Banno F, Kokame K, Okuda T, Honda S, Miyata S, Kato H, Tomiyama Y, Miyata T
- Journal Title
  
  Blood 107
  
  Pages: 3161-3166
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura2006
- Author(s)
  F.Banno, K.Kokame, T.Okuda, S.Honda, S.Miyata, H.Kato, Y.Tomiyama, T.Miyata.
- Journal Title
  
  Blood 107(in press)
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Protein S-K196E mutation as a genetic risk factor for deep vein thrombosis in Japanese patients.2006
- Author(s)
  R.Kimura, S.Honda, T.Kawasaki, H.Tsuji, S.Madoiwa, Y.Sakata, T.Kojima, M.Murata, K.Nishigami, M.Chiku, T.Hayashi, Y.Kokubo, A.Okayama, H.Tomoike, Y.Ikeda.T.Miyata.
- Journal Title
  
  Blood 107(4)
  
  Pages: 1737-1738
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Plasma protein S activity correlates with protein S genotype but is not sensitive to identify K196E mutant carriers.2006
- Author(s)
  Kimura R, Sakara T, KokuboY, Okamoto A, Okayama A, Tomoike H, Miyata T
- Journal Title
  
  J Thromb Haemost 4
  
  Pages: 2010-2013
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Adiponectin acts as an endogenous antithrombotic factor.2006
- Author(s)
  Kato H, Kashiwagi H, Shiraga M, Tadokoro S, Kamae T, Ujiie H, Honda S, Miyata S, Ijiri Y, Yamamoto J, Maeda N, Funahashi T,Kurata Y, Shimomura I, Tomiyama Y, Kanakura Y
- Journal Title
  
  Anterioscler Thromb Vasc Biol 26-1
  
  Pages: 224-230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Journal Article] Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thiombotic thrombocytopenic purpura.2006
- Author(s)
  F. Banno, K. Kokame, T. Okuda, S. Honda, S. Miyata, H. Kato, Y. Tomiyama, T. Miyata
- Journal Title
  
  Blood 107-8
  
  Pages: 3161-3166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Novel compound heterozygote mutations(H234Q/R1206X) of the ADAMTS13 gene in an adult patient with Upshaw-Schulman syndrome showing predominant episodes of repeated acute renal failure.2006
- Author(s)
  Y. Shibagaki, M. Matsumoto, K. Kokame, S. Ohba, T. Miyata, Y. Fujimura, T. Fujita
- Journal Title
  
  Nephrol Dial Transplant 21-5
  
  Pages: 1289-1292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Hypertension susceptibility genes on chromosome 2p24-p25 in a general Japanese population.2005
- Author(s)
  K.Kamide, Y.Kokubo, J.Yang, C.Tanaka, H.Hanada, S.Takiuchi, N.Inamoto, M.Banno, Y.Kawano, A.Okayama, H.Tomoike, T.Miyata
- Journal Title
  
  J.Hypertens 23(5)
  
  Pages: 955-960
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] ミニレビュー/細胞ストレス応答遺伝子NDRG1の機能解析2005
- Author(s)
  奥田智彦, 小亀浩市, 宮田敏行
- Journal Title
  
  生化学 (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570107
[Journal Article] Measurement of ADAMTS13 activity and inhibitors2005
- Author(s)
  Toshiyuki Miyata
- Journal Title
  
  Curr. Opin. Hematol. 12(5)
  
  Pages: 384-389
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570126
[Journal Article] Measurement of ADAMTS 13 activity and inhibitors.2005
- Author(s)
  T.Miyata, K.Kokame, F.Banno
- Journal Title
  
  Curr Opin Hematol 12(5)
  
  Pages: 384-389
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population.2005
- Author(s)
  J.Yang, K.Kamide, Y.Kokubo, S.Takiuchi, C.Tanaka, M.Bannno, Y.Miwa, M.Yoshii, T.Horio, A.Okayama, H.Tomoike, Y.Kawano, T.Miyata
- Journal Title
  
  J.Hypertens 23(8)
  
  Pages: 1497-1505
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay2005
- Author(s)
  K. Kokame, Y. Nobe, Y. Kokubo, A. Okayama, T. Miyata
- Journal Title
  
  Br J Haematol 129-1
  
  Pages: 93-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] FRETS-VWF73, a first fluorogenic substsrate for ADAMTS13 assay.2005
- Author(s)
  K.Kokame, Y.Nobe, Y.Kokubo, A.Okayama, T.Miyata
- Journal Title
  
  Br.J.Haematol 129(1)
  
  Pages: 93-100
- Data Source
  KAKENHI-PROJECT-17390285
[Journal Article] 125th ENMC International Workshop : Neuromuscular Disorders in the Roma (Gypsy) Population.2005
- Author(s)
  Kalaydjieva L, Lochmuller H, Tournev Karcagi Miyata T, et al.
- Journal Title
  
  Neuromuscul Disord 15・1
  
  Pages: 65-71
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570107
[Journal Article] 血栓性血小板減少性紫斑病とADAMTS132005
- Author(s)
  宮田敏行
- Journal Title
  
  循環器病研究の進歩 26(1)
  
  Pages: 90-96
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570126
[Journal Article] Measurement of ADAMTS13 activity and inhibitors2005
- Author(s)
  Toshiyuki Miyata
- Journal Title
  
  Curr.Opin.Hematol. 12(5)
  
  Pages: 384-389
- Data Source
  KAKENHI-PROJECT-17570126
[Journal Article] Identification of strain-specific variants of mouse Adamts13 gene encodingvon Willebrand factor-cleaving protease.2004
- Author(s)
  Banno F, Kaminaka K, Soejima K, Kokame K, Miyata T
- Journal Title
  
  J Biol Chem 279・29
  
  Pages: 30896-30903
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570107
[Journal Article] Pyridoxine 5'-phosphate oxidase is a candidate gene responsible for hypertension in Dahl-S rats.2004
- Author(s)
  Okuda T, Sumiya T, Iwai N, Miyata T
- Journal Title
  
  Biochem Biophys Res Commun 313・3
  
  Pages: 647-653
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570107
[Journal Article] Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves.2004
- Author(s)
  Okuda T, Higashi Y, Kokame K, Tanaka C, Kondoh H, Miyata T
- Journal Title
  
  Mol Cell Biol 24・9
  
  Pages: 3949-3956
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570107
[Patent] プロテインS K196E変異検出法2014
- Inventor(s)
  宮田敏行、秋山正志、丸山慶子、森下英理子
- Industrial Property Rights Holder
  国立循環器病研究センター、栄研化学株式会社、金沢大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-194080
- Filing Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 遺伝性血栓性素因患者における静脈血栓栓塞症の診断と治療2024
- Author(s)
  根木玲子、宮田敏行
- Organizer
  第18回日本血栓止血学会学術標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] 機械弁置換術後妊婦に対する自施設の治療量抗擬固療法プロコトールについての検討2023
- Author(s)
  根木玲子、光黒真菜、岡本章、中島康太、森優花、伊田和史、宮田敏行、吉松淳
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] 遺伝性血管性浮腫の急性発作時におけるFDP/D-dimer比の意義2023
- Author(s)
  本田大介、大澤勲、宮田敏行、尾崎将之、相澤昌史、淺沼克彦．
- Organizer
  第72回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-23K07759
[Presentation] Anticoagulation protocol of therapeutic unfractionated heparin administration for pregnant women with mechanical prosthetic heart valves2023
- Author(s)
  Reiko Neki, Mana Mitsuguro, Akira Okamoto，Kota Nakajima，Yuka Mori，Kazufumi Ida, Toshiyuki Miyata, Jun Yoshimatsu
- Organizer
  ISTH2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] 機械弁置換術後妊婦に対する治療量抗凝固療法の自施設プロトコールの検証2022
- Author(s)
  根木玲子、光黒真菜、岡本章、中島康太、伊田和史、塩野入規、中西篤史、神谷千津子、宮田敏行、吉松淳
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 機械弁置換術後妊婦に対する治療量抗凝固療法の自施設プロトコールの検証2022
- Author(s)
  根木玲子、光黒真菜、岡本章、中島康太、伊田和史、塩野入規、中西篤史、神谷千津子、宮田敏行、吉松淳
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] アンチトロンビン抵抗性を示すプロトロンビン変異を伴う3症例の検討2021
- Author(s)
  5.辻明宏,関根章博,浅野遼太郎,上田仁,青木竜男,保山美由紀,根木玲子, 小亀浩市,宮田敏行,大郷剛
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 補体系の血栓・凝固異常症への関わり2021
- Author(s)
  宮田敏行
- Organizer
  第57回日本補体学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 遺伝カウンセリング外来来談者における遺伝性血栓性素因の遺伝子解析および患者背景に関する検討2021
- Author(s)
  根木玲子、伊田和史、丸山慶子、辻明宏、宮田敏行、小亀浩市
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 遺伝カウンセリング外来来談者における遺伝性血栓性素因の遺伝子解析および患者背景に関する検討2021
- Author(s)
  根木玲子, 伊田和史, 丸山慶子, 辻明宏, 宮田敏行, 小亀浩市
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] アンチトロンビン抵抗性を示すプロトロンビン変異を伴う3症例の検討2021
- Author(s)
  辻明宏,関根章博,浅野遼太郎,上田仁,青木竜男,保山美由紀,根木玲子, 小亀浩市,宮田敏行,大郷剛
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] アンチトロンビン抵抗性を示すプロトロンビン変異を伴う３症例の検討2021
- Author(s)
  辻明宏、関根章博、浅野遼太郎、上田仁、青木竜男、保山美由紀、根木玲子、小亀浩市、宮田敏行、大郷剛
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 遺伝性血栓性素因患者の妊娠分娩管理に関する診療の手引き2021
- Author(s)
  小林隆夫、森下英理子、津田博子、小嶋哲人、根木玲子、宮田敏行、大賀正一、落合正行、安達知子
- Organizer
  第15回日本血栓止血学会学術標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 遺伝カウンセリング外来来談者における遺伝性血栓性素因の遺伝子解析および患者背景に関する検討2021
- Author(s)
  根木玲子, 伊田和史, 丸山慶子, 辻明宏, 宮田敏行, 小亀浩市
- Organizer
  第43回日本血栓止血学会学術集会,
- Data Source
  KAKENHI-PROJECT-21K09530
[Presentation] Biochemical and genetic analyses of complement-related factors in Japanese patients with hypertensive disorders of pregnancy2020
- Author(s)
  Neki R, Miyata T, Ohtani K, Hidaka Y, Ida K, Yokouchi-Konishi T, Nakanishi A, Yoshimatsu J, Kokame K, Wakamiya N, Inoue N
- Organizer
  The XXVIII Congress of the International Society on Thrombosis and Haemostasis (ISTH 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 当院の遺伝カウンセリング外来来談者における遺伝性血栓性素因の遺伝子解析の検討2020
- Author(s)
  伊田和史、丸山慶子、辻明宏、宮田敏行、小亀浩市、根木玲子
- Organizer
  第44回日本遺伝カウンセリング学会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] プロテインS(PS)比活性検査およびPS-K196E変異検出ELISAのPS-K196E変異予測精度に関する検討2020
- Author(s)
  三好剛一、丸山慶子、根木玲子、吉松　淳、浅原彩子、奥久人、小亀浩市、宮田敏行
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Alternative complement pathway activation in the severe hypertensive disorders of pregnancy2020
- Author(s)
  Neki R, Miyata T, Ohtani K, Hidaka Y, Ida K, Yokouchi-Konishi T, Nakanishi A, Yoshimatsu J, Kokame K, Wakamiya N, Inoue N
- Organizer
  The XXXVIII Congress of International Society on Thrombosis and Haemostasis（ISTH 2020）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] Genetic study for idiopathic venous thromboembolism in Japanese using short-read and long-read sequencers: A pilot study of Japanese Group of Idiopathic Thromboembolism2020
- Author(s)
  Tsuji A, Sekine A, Wada H, Morishita E, Ogihar Y, Nogami K, Kojima T, Matsushita T, Yamada N, Ogo T, Neki R, Kokame K, Yasuda S, Miyata T
- Organizer
  The XXXVIII Congress of International Society on Thrombosis and Haemostasis（ISTH 2020）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 特発性血栓症患者のゲノム情報を用いた層別化による病態解明研究2020
- Author(s)
  辻明宏、和田英夫、森下英理子、野上恵嗣、荻原義人、松下正、小嶋哲人、大郷剛、根木玲子、小亀浩市、安田聡、関根章博、宮田敏行
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Genetic study for idiopathic venous thromboembolism in Japanese using short-read and long read sequencers, a pilot study of Japanese Group of Idiopathic Thromboembolism2020
- Author(s)
  Tsuji A, Sekine A, Wada H, Morishita E. Ogihara Y, Nogami K, Kojima T, Matsushita T, Yamada N, Ogo T, Neki R, Kokame K, Yasuda S, MiyataT
- Organizer
  The XXVIII Congress of the International Society on Thrombosis and Haemostasis (ISTH 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 当院の遺伝カウンセリング外来来談者における遺伝性血栓性素因の遺伝子解析の検討2020
- Author(s)
  伊田和史、丸山慶子、辻明宏、宮田敏行、小亀浩市、根木玲子
- Organizer
  第44回日本遺伝カウンセリング学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Kindkin-3欠損血小板の血栓形成が明らかにする血栓形成メカニズム2020
- Author(s)
  加藤恒、伊藤康彦、柏木浩和、西浦伸子、芥田敬吾、小亀浩市、宮田敏行、保仙直毅、金倉譲、冨山佳昭
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Effects of Low-dose Combined Oral Contraceptives and Protein S K196E Mutation on Anticoagulation Factors: A Prospective Observational Study2019
- Author(s)
  T. Miyoshi, H. Oku, S. Asahara, A. Okamoto, K. Kokame, M. Nakai, K. Nishimura, F. Otsuka, A. Higashiyama, J. Yoshimatsu, T. Miyata
- Organizer
  The 27th Congress of the International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 先天性アンチトロンビン欠乏症妊婦の周産期管理はどうあるべきか2019
- Author(s)
  根木玲子、宮田敏行
- Organizer
  日本血栓止血学会第13回SSCシンポジウム血栓性素因部会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 補体制御異常によるTMAの診断と治療, 補体と凝固のクロストーク2019
- Author(s)
  宮田敏行
- Organizer
  第41回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 先天性アンチトロンビン欠乏症妊婦の周産期管理はどうあるべきか？2019
- Author(s)
  根木玲子、宮田敏行
- Organizer
  第13回日本血栓止血学会学術標準化委員会（SSC）シンポジウム
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 当院で妊娠管理した先天性アンチトロンビン欠乏症2症例の抗凝固療法に関する報告2019
- Author(s)
  光黒真菜、根木玲子、岡本章、古田賢二、宮田茂樹、宮田敏行、吉松淳
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 妊娠高血圧症候群における補体マーカー検査と補体関連遺伝子解析の検討2019
- Author(s)
  根木玲子、宮田敏行、伊田和史、小西妙、中西篤史、吉松淳、小亀浩市、大谷克城、日高義彦、若宮伸隆、井上徳光
- Organizer
  第56回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 血栓症と遺伝子バリアント2019
- Author(s)
  宮田敏行
- Organizer
  第15回鈴鹿病態薬学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] Biochemical and genetic analyses of complement-related factors in japanese patients with hypertensive disorders of pregnancy2019
- Author(s)
  Norimitsu Inoue, Reiko Neki, Katsuki Ohtani, Yoshihiko Hidaka, Kazufumi Ida, Tae Yokouchi-Konishi, Atsushi Nakanishi, Jun Yoshimatsu, Koichi Kokame, Nobutaka Wakamiya, Toshiyuki Miyata
- Organizer
  17th European Meeting on Complement in Human Disease(EMCHD2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 妊娠高血圧症候群における補体マーカー検査および補体関連遺伝子解析についての検討2019
- Author(s)
  根木玲子、宮田敏行、伊田和史、小西妙、中西篤史、吉松淳、小亀浩市、大谷克城、日高義彦、若宮伸隆、井上徳光
- Organizer
  日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] Activated Partial Thromboplastin Time-based Unfractionated Heparin Dosing Protocol for Pregnant Patients2019
- Author(s)
  Reiko Neki, Mana Mitsuguro, Akira Okamoto, Kazufumi Ida, Takekazu Miyoshi, Chizuko Kamiya, Naoko Iwanaga, Toshiyuki Miyata, Jun Yoshimatsu
- Organizer
  The XXXVII Congress of International Society on Thrombosis and Haemostasis（ISTH2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] ホルモン補充周期法による不妊治療中に脳静脈洞血栓症を発症した先天性アンチトロンビン欠乏症の検討2019
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、宮田敏行、丸山慶子、小亀浩市
- Organizer
  第34回日本女性医学学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 妊娠初期に静脈血栓塞栓症を発症した先天性プロテインS欠乏症の遺伝子解析の検討2019
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、小亀浩市、宮田敏行
- Organizer
  第5回日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 静脈血栓塞栓症と血液凝固制御能2019
- Author(s)
  宮田敏行
- Organizer
  第71回日本産婦人科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Venous thromboembolism and TTP, aHUS2019
- Author(s)
  Toshiyuki Miyata
- Organizer
  The 41th Congress of the Japanese Society on Thrombosis and Hemostasis
- Invited
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 組織因子経路インヒビターとプロテインSの最近の話題2018
- Author(s)
  宮田敏行
- Organizer
  第40回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 不妊治療中に脳静脈洞血栓症を発症した先天性アンチトロンビン欠乏症症例の検討2018
- Author(s)
  伊田和史、根木玲子、光黒真菜、岡本章、丸山慶子、小亀浩市、宮田敏行
- Organizer
  第42回日本遺伝カウンセリング学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 妊娠を契機に深部静脈血栓症を発症した先天性アンチトロンビン欠乏症症例の遺伝学的検査の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、丸山慶子、小亀浩市、宮田敏行
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 妊娠を契機に深部静脈血栓症を発症した先天性アンチトロンビン欠乏症症例の遺伝学的検査の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、丸山慶子、小亀浩市、宮田敏行
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] Impact of different oral contraceptives on anticoagulation factors in Japanese women.2018
- Author(s)
  Miyoshi T, Okamoto A, Mitsuguro M, Neki R, Uchida Y, Kokame K, Miyata T.
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 抗血小板薬のファーマコゲノミクス2018
- Author(s)
  宮田敏行、田中智貴、宮田茂樹、長束一行
- Organizer
  第43回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 妊娠高血圧症候群における補体関連因子の検討2018
- Author(s)
  根木玲子、中西篤史、小西妙、堀内縁、吉松淳、宮田敏行、井上徳光、若宮伸隆
- Organizer
  第39回日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] シンポジウム1 特発性血栓症「遺伝性血栓性素因妊婦の周産期管理」2018
- Author(s)
  根木玲子、宮田敏行
- Organizer
  第19回日本検査血液学会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 閉経後に深部静脈血栓症を発症した先天性プロテインS欠乏症の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、小亀浩市、宮田敏行
- Organizer
  第33回日本女性医学学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] Impact of different oral contraceptives on anticoagulation factors in Japanese women2018
- Author(s)
  Miyoshi T, Okamoto A, Mitsuguro M, Neki R, Uchida Y, Kokame K, Miyata T
- Organizer
  第40回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 濃厚な家族歴を有する静脈血栓症症例における先天性プロテインS欠乏症の遺伝子解析の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、柳生剛、小亀浩市、宮田敏行
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 閉経後に深部静脈血栓症を発症した先天性プロテインS欠乏症の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、小亀浩市、宮田敏行
- Organizer
  第33回日本女性医学学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] 濃厚な家族歴を有する静脈血栓症症例における先天性プロテインS欠乏症の遺伝子解析の検討2018
- Author(s)
  根木玲子、伊田和史、光黒真菜、岡本章、柳生剛、小亀浩市、宮田敏行
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09277
[Presentation] シンポジウム７「心房細動と脳卒中を考える」、「新たな抗凝固薬の開発」2017
- Author(s)
  宮田敏行
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪市、大阪府
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] “Differences in Prothrombotic States among Races/Regions”, Session 129: Antithrombotic Therapy Specific to Races/Regions (in the NOAC Era)2017
- Author(s)
  Toshiyuki Miyata
- Organizer
  International Stroke Conference 2017
- Place of Presentation
  Houston, USA
- Year and Date
  2017-02-22
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 産科領域における遺伝性血栓性素因の診療.2017
- Author(s)
  根木玲子宮田敏行.
- Organizer
  第11回日本血栓止血学会学術標準化委員会シンポジウム　血栓性素因部会.
- Place of Presentation
  野村コンファレンスプラザ日本橋, 東京
- Data Source
  KAKENHI-PROJECT-26462507
[Presentation] Mouse geneticsと血栓止血学2017
- Author(s)
  宮田敏行、坂野史明、田嶌優子、柳本広二、小亀浩市
- Organizer
  第39回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] Genetic Risk Factors of Venous Thromboembolism in Humans and Mice2017
- Author(s)
  Toshiyuki Miyata
- Organizer
  XXVI Congress of the International Society on Thrombosis and Haemostasis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 非典型溶血性尿毒症症候群患者におけるプラスミノーゲン A620T変異2016
- Author(s)
  宮田敏行、内田裕美子、藤村吉博、吉田瑤子、加藤秀樹、南学正臣
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] 血栓形成メカニズムの最新のトピックス、「静脈血栓症の発症メカニズム」2016
- Author(s)
  宮田敏行
- Organizer
  第41回日本脳卒中学会総会
- Place of Presentation
  札幌市、北海道
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] Thrombophilia in East Asian Countries. Are there any genetic differences in these countries?2016
- Author(s)
  Toshiyuki Miyata
- Organizer
  The 9th Congress of the Asian-Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] Plasminogen Tochigi mice with severely reduced plasminogen activity exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions2016
- Author(s)
  Toshiyuki Miyata, Yuko Tashima, Fumiaki Banno, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto
- Organizer
  Gordon Research Conference on Hemostasis
- Place of Presentation
  Stowe, Vermont, USA
- Year and Date
  2016-07-24
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome2016
- Author(s)
  Toshiyuki Miyata, Yumiko Uchida, Yoko Yoshida, Hideki Kato, Masanori Matsumoto, Koichi Kokame, Yoshihiro Fujimura, Masaomi Nangaku
- Organizer
  XXVIth International Complement Workshop
- Place of Presentation
  金沢市
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-16K09834
[Presentation] αIIbβ3活性化変異、αIIb(R990W)KIマウスは巨大血小板減少症とともに血小板機能障害をきたす2015
- Author(s)
  柏木浩和, 清水一亘, 國島伸治, 坂野史明, 加藤恒, 森川陽一郎, 田所誠司, 小亀浩市, 本田繁則, 宮田敏行, 金倉譲, 冨山佳昭
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府市総合市民会館（甲府市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] インテグリンαIIbβ3活性化変異、αIIb(R990W)ノックインマウスの解析2014
- Author(s)
  清水一亘, 柏木浩和, 森川陽一郎, 加藤恒, 田所誠司, 坂野史明, 小亀浩市, 本田繁則, 金倉譲, 宮田敏行, 冨山佳昭
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] プロテインS徳島は日本人に特有の変異なのか？2014
- Author(s)
  宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 本邦における非典型溶血性尿毒症症候群患者の登録状況と診断法の確立2014
- Author(s)
  吉田瑶子、内田裕美子、芦田明、服部元史、松本雅則、宮田敏行、藤村吉博
- Organizer
  第49回　日本小児腎臓病学会学術集会
- Place of Presentation
  秋田ビューホテル
- Data Source
  KAKENHI-PROJECT-25860685
[Presentation] ADAMTS13遺伝子欠損マウスの静脈血栓塞栓症状の解析2014
- Author(s)
  田嶌優子, 坂野史明, 宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] マウス敗血症モデルによるvon Willebrand 因子－ADAMTS13軸の炎症制御機構2014
- Author(s)
  粕田承吾, 松井英人, 大野史郎, 西尾健治, 坂野史明, 秋山正志, 宮田敏行, 羽竹勝彦, 杉本充彦
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] 血栓症形成の分子メカニズムとその制御　基礎：凝固系、静脈血栓症2014
- Author(s)
  宮田敏行
- Organizer
  2014年度千里ライフサイエンスセミナー
- Place of Presentation
  千里ライフサイエンスセンター、大阪府、豊中市
- Year and Date
  2014-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 深部静脈血栓症モデルを用いた日本人の血栓症モデルマウスの解析2014
- Author(s)
  坂野史明, 田嶌優子, 小亀浩市, 宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] GT-like phenotype with macrothrombocytopenia induced by αIIbβ3 activating mutation in mice2014
- Author(s)
  Kiyomizu K, Kashiwagi H, Kunishima H, Banno F, Morikawa Y, Kato H, Tadokoro S, Kokame K, Honda S, Miyata T, Kanakura Y, Tomiyama Y
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Analysis of mice carrying northeast Asian-specific genetic mutations in thrombosis2014
- Author(s)
  Banno F, Tashima Y, Kita T, Matsuda Y, Yanamoto H, Kokame K, Miyata T
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都市）
- Year and Date
  2014-04-15
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] 日本人に高頻度に見られるプラスミノーゲン栃木変異をもつ遺伝子改変マウスの血栓傾向の解析2014
- Author(s)
  田嶌優子, 坂野史明, 喜多俊行, 松田泰幸, 柳本広二, 宮田敏行
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（豊中市）
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] 定量的溶血試験と遺伝子解析を用いた本邦aHUS患者の病態解析2014
- Author(s)
  吉田瑶子、Xinping Fan、大山良文、古久保哲朗、岩本顕聰、森俊雄、松本雅則、池島裕子、宮田敏行、藤村吉博
- Organizer
  第36回　日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-25860685
[Presentation] TTPとHUS（総会長シンポジウム）、TTP/HUSの遺伝子解析2014
- Author(s)
  宮田敏行
- Organizer
  第62回日本輸血・細胞治療学会総会
- Place of Presentation
  奈良県新公会堂、奈良県、奈良市
- Year and Date
  2014-05-16
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] マウスプラスミノーゲン栃木変異は血漿プラスミン活性を低下させるが血栓塞栓症の原因にはならない2013
- Author(s)
  田嶌優子, 坂野史明, 喜多俊行, 松田泰幸, 柳本広二, 宮田敏行
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] Thrombophilia and venous thromboembolism.2013
- Author(s)
  Toshiyuki Miyata
- Organizer
  Sysmex Scientific Seminar
- Place of Presentation
  Taipei(招待講演)
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Familial screening in the case of Budd-Chiari syndrome with multiple thrombi due to Arg42Ser mutation in the protein C gene2013
- Author(s)
  Jun Muratsu, Atsuyuki Morishima, Masayoshi Kukida, Anzu Tanaka, Xinping Fan, Toshiyuki Miyata, Katsuhiko Sakaguchi
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Exacerbated venous thromboembolism in mice with the protein S Tokushima mutation2013
- Author(s)
  Fumiaki Banno, Toshiyuki Kita, Hiroji Yanamoto, Yuko Tashima, Koichi Kokame, Toshiyuki Miyata
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis2013
- Author(s)
  Yoko Yoshida, Xinping Fan, Yoshifumi Ohyama, Tetsuro Kokubo, Masanori Matsumoto, Hideo Yagi, Hiroko Shirotani-Ikejima, Toshiyuki Miyata, Yoshihiro Fujimura
- Organizer
  55th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] A long-term phenotype analysis of 51 patients with Upshaw–Schulman syndrome in Japan, with special references to pregnancy and renal failure that requires hemodialysis2013
- Author(s)
  Yoshihiro Fujimura, Yumi Yoshii, Masanori Matsumoto, Ayami Isonishi, Hideo Yagi, Koichi Kokame, Toshiyuki Miyata
- Organizer
  55th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 本邦の非典型溶血性尿毒症症候群（aHUS）の患者登録とその表現型－遺伝子型解析2013
- Author(s)
  吉田瑶子、範新萍、本田繁則、芦田明、服部元史、松本雅則、大山良文、古久保哲朗、南学正臣、宮田敏行、藤村吉博
- Organizer
  第48回　日本小児腎臓病学会学術集会
- Place of Presentation
  あわぎんホール
- Data Source
  KAKENHI-PROJECT-25860685
[Presentation] 疾患モデルマウスを用いた血栓性疾患の研究2013
- Author(s)
  宮田敏行
- Organizer
  医薬基盤研究所セミナー
- Place of Presentation
  箕面市
- Invited
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] sHUSの遺伝子解析2013
- Author(s)
  宮田敏行
- Organizer
  日本血栓止血学会SSCシンポジウム2013VWD/TTP部会
- Place of Presentation
  東京都(招待講演)
- Year and Date
  2013-01-12
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Registry of congenital atypical HUS in Japan2013
- Author(s)
  Yoshihiro Fujimura, Yoko Yoshida, Xinping Fan, Toshiyuki Miyata
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam,Netherlands
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] ADAMTS13の正常な分泌にはシクロフィリンBによるプロリン残基異性化が必要である2013
- Author(s)
  小亀浩市、秋山正志、宮田敏行
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Generation and characterization of homozygous plasminogen-Tochigi mutant mice bearing reduced fibrinolytic activity2013
- Author(s)
  Yuko Tashima, Fumiaki Banno, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto, Toshiyuki Miyata
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] 凝固系・補体系の接点としての血管内皮細胞障害2013
- Author(s)
  宮田敏行
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  旭川市
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Pharmacogenomicsは抗血小板剤の個別化医療の救世主となり得るか？2013
- Author(s)
  宮田敏行、宮田茂樹、長束一行
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形市
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 血栓性細小血管障害症の発症機構と診断・治療2013
- Author(s)
  宮田敏行
- Organizer
  第33回ヒューマンサイエンス基礎研究講習会
- Place of Presentation
  吹田市
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 血栓性細小血管障害症の分子機構2013
- Author(s)
  宮田敏行
- Organizer
  TTMフォーラム(
- Place of Presentation
  東京都(招待講演)
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Generation of protein S-Tokushima mutant mice to provide an in vivo evaluation system for thrombosis in Japanese2013
- Author(s)
  Fumiaki Banno, Toshiyuki Kita, Hiroji Yanamoto, Yuko Tashima, Koichi Kokame, Toshiyuki Miyata
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis.2013
- Author(s)
  Yoshida Y, Fan X, Ohyama Y, Kokubo T, Matsumoto M, Yagi H, Shirotani-Ikejima H, Miyata T, FujimuraY.
- Organizer
  55th Annual meeting of American Society of Hematology.
- Place of Presentation
  Ernest N. Morial Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-25860685
[Presentation] 哺乳類細胞を用いたADAMTS13ドメインの一過性大量発現2013
- Author(s)
  平井秀憲、秋山正志、宮田敏行
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  鳥取市
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 日本における先天性ADAMTS13欠損症の遺伝子解析2013
- Author(s)
  樋口（江浦）由佳, 小亀浩市, 松本雅則, 藤村吉博, 宮田敏行
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] プロテインS徳島(K196E)変異がマウスの肺塞栓症および虚血性脳梗塞に及ぼす影響2012
- Author(s)
  坂野史明、喜多俊行、柳本広二、小亀浩市、宮田敏行
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] 血栓形成の分子機構2012
- Author(s)
  宮田敏行
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台市(招待講演)
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Protective role of ADAMTS13 for myocardium in mouse model of experimental myocardial infarction2012
- Author(s)
  Masaaki Doi, Hideto Matsui, Yukiji Takeda, Yoshihiko Saito, Maiko Takeda, Yasunori Matsunari, Kenji Nishio, Midori Shima, Fumiaki Banno, Masashi Akiyama, Koichi Kokame, Toshiyuki Miyata,Mitsuhiko Sugimoto
- Organizer
  54th American Society of Hematology, Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] 血栓性素因の成因と病態2012
- Author(s)
  宮田敏行
- Organizer
  第35回シスメックス学術セミナー
- Place of Presentation
  神戸市(招待講演)
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 血栓形成の分子機構2012
- Author(s)
  宮田敏行
- Organizer
  日本バイオマテリアル学会シンポジウム2012、シンポジウム : 血液適合ト生バイオマテリアル
- Place of Presentation
  仙台市
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] ADAMTS13 improving the cell engraftment efficacy in mouse model of bone marrow transplantation2012
- Author(s)
  Hideto Matsui, Masaaki Doi, Yasunori Matsunari, Maiko Takeda, Kenji Nishio, Midori Shima, Kenji Soejima, Fumiaki Banno, Masashi Akiyama, Koichi Kokame, Toshiyuki Miyata, Mitsuhiko Sugimoto
- Organizer
  54th American Society of Hematology, Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] 非定型溶血性尿毒症症候群の遺伝的背景2012
- Author(s)
  宮田敏行, 他25名
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] ADAMTS13研究の最先端、血栓止血学・血管生物学の最近の進歩2011
- Author(s)
  宮田敏行、小亀浩市、秋山正志、武田壮一、坂野史明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] ADAMTS13研究の最先端2011
- Author(s)
  宮田敏行, 他4名
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Generation of knock-in mice carrying a K196E point mutation in protein S2011
- Author(s)
  Fumiaki Banno, Toshiyuki Kita, Hiroji Yanamoto, Koichi Kokame, Koji Iihara, Toshiyuki Miyata
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] Thrombotic thrombocytopenic purpura and ADAMTS132011
- Author(s)
  Toshiyuki Miyata
- Organizer
  3rd SIRIC-NCVC Joint Symposium
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] ADAMTS13研究の最先端2011
- Author(s)
  宮田敏行、小亀浩市、秋山正志、武田壮一、坂野史明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] Imaging analysis of the interaction between unusually large von-Willebrand factor multimers and platelets on vascular endothelial cells in living animals2011
- Author(s)
  Tomasz Brzoska, Miroslaw Rybaltowski, Yuko Suzuki, Hideo Mogami, Iwona Chlebinska, Aki Tanaka, Fumiaki Banno, Toshiyuki Miyata, Tetsumei Urano
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] Imaging analysis of the interaction between unusually large von-Willebrand factor multimers and platelets on vascular endothelial cells in living animals2011
- Author(s)
  Tomasz Brzoska, Miroslaw Rybaltowski, Yuko Suzuki, Hideo Mogami, Iwona Chlebinska, Aki Tanaka, Fumiaki Banno, Toshiyuki Miyata, Tetsumei Urano
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] シンポジウム6血栓止血学・血管生物学の最近の進歩、ADAMTS13研究の最先端2011
- Author(s)
  宮田敏行、小亀浩市、秋山正志、武田壮一、坂野史明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Thrombotic thrombocytopenic purpura and ADAMTS132011
- Author(s)
  Toshiyuki Miyata
- Organizer
  3^<rd> SIRIC-NCVC Joint Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] Generation of knock-in mice carrying a K196E point mutation in protein S2011
- Author(s)
  Fumiaki Banno, Toshiyuki Kita, Hiroji Yanamoto, Koichi Kokame, Koji Iihara, Toshiyuki Miyata
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] 教育講演「日本人の血栓性素因」2010
- Author(s)
  宮田敏行
- Organizer
  第20回日本産婦人科・新生児血液学会
- Place of Presentation
  浜松市
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] 日本人の血栓性素因2010
- Author(s)
  宮田敏行
- Organizer
  第20回日本産婦人科・新生児血液学会
- Place of Presentation
  浜松市
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Genetic disorders related to coagulopathy prevalent in the Far East.2009
- Author(s)
  Toshiyuki Miyata
- Organizer
  The APSTH-JSTH Joint Symposium, XXII Congress of the international Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston, USA
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] プロテインS欠損症:国立循環器病センターでの研究、血栓性素因部会「血栓性素因・プロテインS欠乏症/欠損症をめぐる最近の話題」2009
- Author(s)
  宮田敏行
- Organizer
  第4回日本血栓止血学会SSC2009シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] 教育講演2、遺伝子情報を用いる血栓症の個別化医療2009
- Author(s)
  宮田敏行
- Organizer
  第12回日本栓子検出と治療学会
- Place of Presentation
  大阪市
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] The APSTH-JSTH Joint Symposium, Genetic disorders related to coagulopathy prevalent in the Far East2009
- Author(s)
  Toshiyuki Miyata
- Organizer
  XXII Congress of the international Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston, USA
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Genetic risk factors for venous thromboembolism in Japanese, Invited speaker2008
- Author(s)
  Toshiyuki Miyata
- Organizer
  The 19th Great Wall International Congress of Cardiology
- Place of Presentation
  Beijing
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Thrombophilia in Asian Countries : Myth or Reality? Invited speaker, Genetic risk factors for deep vein thrombosis among Japanese2008
- Author(s)
  Toshiyuki Miyata
- Organizer
  5th Congress of Asian-Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] シンポジウム4「血栓止血・血管生物学」Thrombosis and hemostasis/vascular biology,静脈血栓塞栓症の遺伝的素因、Genetic risk factor for thrombophilia2008
- Author(s)
  宮田敏行
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Binding of ADAMTS13 with Lys-plasminogen, Invited Hot Topic Speaker2008
- Author(s)
  Toshiyuki Miyata
- Organizer
  Gordon Research Conference, Hemostasis 2008
- Place of Presentation
  Waterville Valley Resort, USA.
- Data Source
  KAKENHI-PROJECT-20057036
[Presentation] Binding of ADAMTS13 with Lys-plasminogen2008
- Author(s)
  Toshiyuki MIYATA, Yongchol SHIN, Koichi KOKAME, Masashi AKIYAMA, Kenji SOEJIMA
- Organizer
  Gordon Research Conference, Hemostasis 2008
- Place of Presentation
  Waterville Valley Resort, USA
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] Clinical implications of ADAMTS-13 polymorphisms, Invited speaker2008
- Author(s)
  Toshiyuki Miyata
- Organizer
  Joint Symposium of 3rd United Kingdom-Japan Platelet Conference (UKJPS) and Asian-Pacific Society on Thrombosis and Haemostasis (APSTH), 5th Congress of Asian-Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-20057036
[Presentation] Binding of ADAMTS13 with Lys-plasminogen.2008
- Author(s)
  Toshiyuki MIYATA, et al.
- Organizer
  Invited Hot Topic Speaker, Gordon Research Conference, Hemostasis 2008.
- Place of Presentation
  Waterville Valley Resort, USA
- Data Source
  KAKENHI-PROJECT-20390278
[Presentation] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency.2007
- Author(s)
  Yin T, Takeshita S, Sato Y, Sakata T, Shin Y, Honda S, Kawasaki T, Tsuji H, Kojima T, Madoiwa S, Sakata Y, Murata M, Ikeda Y, Miyata T
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  賢島宝生苑・志摩観光ホテル
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Presentation] Measurements of ADAMTS13 activity, invited speaker2007
- Author(s)
  Koichi Kokame, Toshiyuki Miyata
- Organizer
  Subcommittee on vWF(and ADAMT13) at SSC meeting
- Place of Presentation
  Geneva
- Year and Date
  2007-07-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency.2007
- Author(s)
  Yin T, Takeshita S, Sato Y, Sakata T, Shin Y, Honda S, Kawasaki T, Tsuji H, Kojima T, Madoiwa S, Sakata Y, Murata M, Ikeda Y, Miyata T
- Organizer
  Congress of the Japanese Society on Thrombosis Hemostasis
- Place of Presentation
  Mie
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Presentation] Genetic factors related to thrombophilia, Protein S-K196E mutation as a genetic risk factor for deep vein thrombosis among Japanese patients2007
- Author(s)
  Toshiyuki Miyata
- Organizer
  第21回国際血栓止血学会シンポジウム
- Place of Presentation
  ジュネーブ市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] Effects of complete deficiency and C-terminal deletion of ADAMTS13 on hemostatic function in mice2007
- Author(s)
  Fumiaki Banno, Koichi Kokame, Tomohiko Okuda, Shigenori Honda, Shigeki Miyata, Hisashi Kato, Yoshiaki Tomiyama, Toshiyuki Miyata
- Organizer
  International Mammalian Genome Conference
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Presentation] Effects of complete deficiency and C-terminal deletion of ADAMTS13 on hemostatic function in mice2007
- Author(s)
  Fumiaki Banno, Koichi Kokame, Tomohiko Okuda, Shigenori Honda, Shigeki Miyata, Hisashi Kato, Yoshiaki Tomiyama, Toshiyuki Miyata
- Organizer
  International Mammalian Genome Conference 2007
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] ADAMTS13 and its related issues, invited lecture2006
- Author(s)
  Toshiyuki Miyata
- Organizer
  Gordon Research Conference Hemostasis
- Place of Presentation
  Colby College, Waterville, ME, USA.
- Year and Date
  2006-07-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] ADAMTS13 and its related issues, invited lecture2006
- Author(s)
  Toshiyuki Miyata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Waterville, ME, USA.
- Year and Date
  2006-07-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591095
[Presentation] ADAMTS13 : patient analysis, assay method, and knockout mouse, invited speaker2005
- Author(s)
  Toshiyuki Miyata
- Organizer
  Firth Bari International Conference on Hemophilia and Allued Disorders, von Willebrand factor(including ADAMTS-13) and Platelat
- Place of Presentation
  Pizzomunno, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] Assays for ADAMTS13, Symposium : Regulation of von Willebrand factor function, invited speaker2005
- Author(s)
  Toshiyuki Miyata
- Organizer
  The International Society on Thrombosis and Haemostasis XXth Congress
- Place of Presentation
  Sydney, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390285
[Presentation] Analysis of mice carrying northeast Asian-specific genetic mutations in thrombosis
- Author(s)
  Fumiaki Banno, Yuko Tashima, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto, Koichi Kokame, Toshiyuki Miyata
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  都メッセ、京都府、京都市
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 腎障害を示した先天性血栓性血小板減少性紫斑病患者の補体制御因子の遺伝子解析
- Author(s)
  池島裕子、Xinping Fan、平井秀憲、本田繁則、吉田瑶子、藤村吉博、Johanna A. Kremer Hovinga、Bernhard Lammle、宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 血栓性細小血管障害症の分子機構
- Author(s)
  宮田敏行
- Organizer
  TTMフォーラム
- Place of Presentation
  東京都
- Invited
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] プラスミノーゲン栃木変異ホモ接合体マウスの血栓傾向の解析
- Author(s)
  田嶌優子, 坂野史明, 喜多俊行, 松田泰幸, 柳本広二, 宮田敏行
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形国際ホテル（山形市）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Exacerbated venous thromboembolism in mice with the protein S Tokushima mutation
- Author(s)
  Banno F, Kita T, Yanamoto H, Tashima Y, Kokame K, Miyata T
- Organizer
  The International Society on Thrombosis and Haemostasis XXIV Congress
- Place of Presentation
  Amsterdam RAI（Amsterdam, Netherlands）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Thrombotic thrombocytopenic purpura and ADAMTS13”
- Author(s)
  Toshiyuki Miyata
- Organizer
  2014 Suzhou International Symposium on Basic and Translational Vascular Research
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-10-11 – 2014-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 妊娠中の長期ヘパリン投与による抗凝固療法のモニタリングについての検討
- Author(s)
  根木玲子、光黒真菜、小西博巳、澤田雅美、丸岡寛、田中佳世、井出哲弥、三好剛一、神谷千津子、田中博明、吉田昌史、岩永直子、山中薫、岡本章、城之内芳枝、宮田茂樹、佐野道孝、宮田敏行、吉松淳
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26462507
[Presentation] 血栓形成の分子機構
- Author(s)
  宮田敏行
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-23659494
[Presentation] ダイレクトシークエンシング，定量PCR，次世代シークエンシングを用いたTTP患者の遺伝子解析
- Author(s)
  樋口(江浦)由佳、小亀浩市、高蓋寿朗、田中亮二郎、小林　光、石田文宏、久永修一、松本雅則、藤村吉博、宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Molecular effects of four mutations identified in the D3 region of thrombomodulin in patients with atypical hemolytic uremic syndrome.
- Author(s)
  Ashida A, Yamamoto D, Yoshida Y, Matsumoto M, Miyata T, Hattori M, Fujimura Y, Tamai H.
- Organizer
  American Society of Nephrology
- Place of Presentation
  Philadelphia（USA）
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25860685
[Presentation] マウス急性心筋梗塞モデルにおけるADAMTS13の心筋保護作用
- Author(s)
  土井政明, 松井英人, 竹田征治, 斎藤能彦, 武田麻衣子, 松成泰典, 西尾健治, 嶋緑倫, 坂野史明, 秋山正志, 小亀浩市, 宮田敏行, 杉本充彦
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形国際ホテル（山形市）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Symposium 2, Thrombosis, leukocytes and vascular cells, Registry of hereditary thrombotic microangiopathies in Japan
- Author(s)
  Toshiyuki Miyata, Yoshihiro Fujimura
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  都メッセ、京都府、京都市
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 静脈血栓症のリスクとなるプロテインS K196E変異の地理的分布
- Author(s)
  宮田敏行、Wanyang Liu、Tong Yin、奥田裕子、原田浩二、Xinping Fan、小泉昭夫
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] ADAMTS13遺伝子欠損マウスの静脈血栓塞栓症状の解析
- Author(s)
  田嶌優子、坂野史明、小亀浩市、宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Generation and characterization of homozygous plasminogen-Tochigi mutant mice bearing reduced fibrinolytic activity
- Author(s)
  Tashima Y, Banno F, Kita T, Matsuda Y, Yanamoto H, Miyata T
- Organizer
  The International Society on Thrombosis and Haemostasis XXIV Congress
- Place of Presentation
  Amsterdam RAI（Amsterdam, Netherlands）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] マウス骨髄移植モデルにおけるADAMTS13の移植ドナー細胞生着促進効果
- Author(s)
  松井英人, 土井政明, 武田麻衣子, 松成泰典, 西尾健治, 嶋緑倫, 副島見事, 粕田承吾, 坂野史明, 宮田敏行, 杉本充彦
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形国際ホテル（山形市）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Generation of protein S-Tokushima mutant mice to provide an in vivo evaluation system for thrombosis in Japanese
- Author(s)
  Banno F, Kita T, Yanamoto H, Tashima Y, Kokame K, Miyata T
- Organizer
  第35回日本血栓止血学会学術集会, SPCシンポジウム4
- Place of Presentation
  山形国際ホテル（山形市）
- Invited
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] デジタルPCRを用いたADAMTS13遺伝子変異ヘテロ接合性の解析
- Author(s)
  小亀浩市、樋口(江浦)由佳、松本雅則、藤村吉博、宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 日本人に高頻度に見られるプラスミノーゲン栃木変異をもつ遺伝子改変マウスの血栓傾向の解析
- Author(s)
  田嶌優子、坂野史明、喜多俊行、松田泰幸、柳本広二、宮田敏行
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府、豊中市
- Year and Date
  2014-08-08 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 妊娠中の未分画ヘパリン投与による抗凝固療法のモニタリングについての検討
- Author(s)
  釣谷充弘、根木玲子、光黒真菜、澤田雅美、永易洋子、天雲千晶、田中佳世、三好剛一、神谷千津子、田中博明、吉田昌史、岩永直子、岡本章、城ノ内芳枝、宮田茂樹、佐野道孝、宮田敏行、吉松淳
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府、豊中市
- Year and Date
  2014-08-08 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-26462507
[Presentation] ADAMTS13 accelerates the cell engraftment efficacy in mouse model of bone marrow transplantation
- Author(s)
  Matsui H, Doi M, Matsunari Y, Takeda M, Nishio K, Shima M, Soejima K, Banno F, Miyata T, Sugimoto M
- Organizer
  The International Society on Thrombosis and Haemostasis XXIV Congress
- Place of Presentation
  Amsterdam RAI（Amsterdam, Netherlands）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Analysis of mice carrying northeast Asian-specific genetic mutations in thrombosis
- Author(s)
  Fumiaki Banno, Yuko Tashima, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto, Koichi Kokame, Toshiyuki Miyata
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  都メッセ、京都府、京都市
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] 被験血漿中のVIII因子活性が未分画ヘパリンのモニタリング法であるAPTTと抗Xa活性に及ぼす影響
- Author(s)
  光黒真菜, 根木玲子, 岡本章, 城之内芳枝, 宮田茂樹, 佐野道孝, 吉松淳, 宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26462507
[Presentation] “Registry of congenital TMAs in Japan”
- Author(s)
  Masanori Matsumoto, Toshiyuki Miyata, Yoshihiro Fujimura
- Organizer
  The 8th congress of Asia Pacific Society on Thrombosis and Haemostasis- 2014
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2014-10-09 – 2014-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] Generation and characterization of homozygous plasminogen-Tochigi mutant mice bearing reduced fibrinolytic activity
- Author(s)
  Tashima Y, Banno F, Kita T, Matsuda Y, Yanamoto H, Miyata T
- Organizer
  Gordon Research Conferences 2014
- Place of Presentation
  Four Points Sheraton/Holiday Inn Express（Ventura, USA）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] Generation and characterization of homozygous plasminogen-Tochigi mutant mice bearing reduced fibrinolytic activity
- Author(s)
  Tashima Y, Banno F, Kita T, Matsuda Y, Yanamoto H, Miyata T
- Organizer
  Gordon Research Seminar 2014
- Place of Presentation
  Four Points Sheraton/Holiday Inn Express（Ventura, USA）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] マウスプラスミノーゲン栃木変異は血漿プラスミン活性を低下させるが血栓塞栓症の原因にはならない
- Author(s)
  田嶌優子, 坂野史明, 喜多俊行, 松田泰幸, 柳本広二, 宮田敏行
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25461465
[Presentation] プロテインS K196E (PS徳島)変異特異的ELISA法の構築、Construction of ELISA system for specific detection of protein S K196E (PS Tokushima) mutation
- Author(s)
  Keiko Maruyama, Masashi Akiyama, Koichi Kokame, Eriko Morishita, Toshiyuki Miyata
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府、大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] 日本人の非典型溶血性尿毒症症候群患者41人の遺伝子解析
- Author(s)
  宮田敏行、内田裕美子、吉田瑶子、池島裕子、Fan Xinping、芦田明、和田英夫、大塚泰史、中村健治、石川智朗、八田和大、服部元史、久野正貴、才田謙、西尾健治、瀧本智仁、幡谷浩史、大原敦子、川村尚久、波多江健、松本雅則、加藤秀樹、南学正臣、藤村吉博
- Organizer
  第51回補体シンポジウム
- Place of Presentation
  神戸常盤大学、兵庫県、神戸市
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] マウス敗血症モデルによるvon Willebrand 因子：ADAMTS13軸の炎症制御機構
- Author(s)
  粕田承吾、松井英人、大野史郎、西尾健治、坂野史朗、秋山正志、宮田敏行、羽竹勝彦、杉本充彦
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] 日本人に高頻度に見られるプラスミノーゲン栃木変異をもつ遺伝子改変マウスの血栓傾向の解析
- Author(s)
  田嶌優子、坂野史明、喜多俊行、松田泰幸、柳本広二、宮田敏行
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府、豊中市
- Year and Date
  2014-08-08 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-25670454
[Presentation] 定量的溶血試験と遺伝子解析を用いた本邦aHUS患者の病態解析
- Author(s)
  吉田瑶子、範　新萍、古久保哲朗、岩本顕聰、森　俊雄、松本雅則、池島裕子、宮田敏行、藤村吉博
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24390250
[Presentation] ADAMTS13遺伝子欠損マウスの静脈血栓塞栓症状の解析
- Author(s)
  田嶌優子、坂野史明、小亀浩市、宮田敏行
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター、大阪府、大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25670454
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MIYATA TOSHIYUKI 宮田 敏行

MIYATA Toshiyuki 宮田 敏行

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Genetic background of thrombophilia using third generation DNA sequencingPrincipal Investigator

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Studies on thrombotic risk of protein S K196E mutationPrincipal Investigator

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Production and analysis of Bac-TRAP mice that express fluorescent proteins driven by thrombomodulin or endothelial cell protein C receptor promoterPrincipal Investigator

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Thrombotic phenotypes of two antithrombotic factors, protein S and ADAMTS13Principal Investigator

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Production and analysis of Adamts13-Bac-TRAP mice that express fluorescent protein EGFP driven by Adamts13 promoterPrincipal Investigator

MIYATA TOSHIYUKI 宮田敏行

MIYATA Toshiyuki 宮田敏行