NIKI Toshiro 仁木利郎

… Alternative Names

仁木利郎ニキトシロウ

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Researcher Number	90198424
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2023: 自治医科大学, 医学部, 客員教授 2022 – 2023: 自治医科大学, 医学部, 教授 2008 – 2020: Jichi Medical University, 医学部, 教授 2005 – 2006: 自治医科大学, 医学部, 教授 2001 – 2004: 東京大学, 大学院・医学系研究科, 助教授 … More 2000: 国立がんセンター, 研究所・病理部, 室長 2000: National Cancer Center Research Institute, Pathology Division, Section Head, 病理部, 室長 1999: 国立がんセンター, 研究所・病理部, 主任研究官 1998: 国立がんセンター, 研究所病理部, 主任研究官 Less
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related / Human pathology / Experimental pathology Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 49020:Human pathology-related / Biological Sciences
Keywords	Principal Investigator 肺腺癌 / 転移 / 肺癌 / 浸潤 / invasion / lung adenocarcinoma / VEGF / 上皮間葉転換 / 分子標的 / スフェロイド … More / 病理組織 / 細胞分化 / pathology / signal transduction / cell and tissue / cancer / 病理学 / シグナル伝達 / 細胞・組織 / 癌 / wound healing / inflammation / 創傷治癒 / 炎症 / RT-PCR / prognosis / laminin / matastasis / angiogenesis / 血管新生 / 予後因子 / 肺がん / ラミニン / MAPK / NF-kB / 細胞外基質 / エピジェネティクス / メチル化 / 分化形質 / エピジェネティックス / マウス … More Except Principal Investigator 化学発光ライブイメージング / 可視化 / 微小転移モデル / 肺癌 / 分子標的 / バイオマーカー / non-TRU type / TTF-1 / 肺腺癌 lung adenocarcinoma / non-TRU type肺腺癌 / 発現不均一性 / 低酸素 / 瘢痕形成 / 浸潤部 / バイオインフォマティクス / TSLC1 / p73 / マイクロダイセクション / DNAチップ / 遺伝子発現 / 浸潤 / 悪性度 / 肺腺癌 Less

Non-TRU type 肺腺癌を層別化するバイオマーカーならびに分子標的の同定
- Principal Investigator
  
  三浦珠希
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Jichi Medical University
生体内で可視化できる肺癌の超微小転移モデルの確立
- Principal Investigator
  
  坪地宏嘉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Jichi Medical University
Analysis of the mechanisms of metastasis of lung adenocarcinoma by low-attachment spheroid culturePrincipal Investigator
- Principal Investigator
  
  仁木利郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Jichi Medical University
Integrated regulatory mechanism that govern differentiation and survival of driver-mutation-independent lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  niki toshiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Jichi Medical University
Epigenetic abnormalities and reprogramming in epithelial-mesenchymal transition of lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Niki Toshiro
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Systemic generation of metastatic models of lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  niki toshiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Identification of molecular target and its therapeutic application for micropapillary adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  NIKI Toshiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Molecular targets for lung adenocarcinoma with epithelial-mesenchymal transition : identification and their application for diagnosis and therapy.Principal Investigator
- Principal Investigator
  
  NIKI Toshiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Investigation of genes induced at the invasive front of lung adenocarcinomasPrincipal Investigator
- Principal Investigator
  
  NIKI Toshiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Regulatory mechanisms for wound-related gene expression at invasive front of Lung adenocarcinomasPrincipal Investigator
- Principal Investigator
  
  NIKI Toshihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  The University of Tokyo
肺腺癌の診断,悪性度診断の客観化を目指した遺伝子診断システムの確立
- Principal Investigator
  
  深山正久
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Cancer-Stromal Interaction in Lung AdenocarcinomaPrincipal Investigator
- Principal Investigator
  
  NIKI Toshiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  NATIONAL CANCER CENTER

[Book] 《標準臨床検査学》病理学・病理検査学2012
- Author(s)
  仁木利郎(共同編集、執筆)
- Total Pages
  296
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Genetic and phenotypic determinants of morphologies in 3D cultures and xenografts of lung tumor cell lines2023
- Author(s)
  Matsubara Daisuke、Yoshimoto Taichiro、Akolekar Ninad、Totsuka Takashi、Amano Yusuke、Kihara Atsushi、Miura Tamaki、Isagawa Yuriko、Sakuma Yuji、Ishikawa Shumpei、Ushiku Tetsuo、Fukayama Masashi、Niki Toshiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1757-1770
- DOI
  10.1111/cas.15702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15412, KAKENHI-PROJECT-22K06945
[Journal Article] Dual inhibition of KIF11 and BCL2L1 induces apoptosis in lung adenocarcinoma cells2023
- Author(s)
  Sakuma Yuji、Hirai Sachie、Sumi Toshiyuki、Niki Toshiro、Yamaguchi Miki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 678 Pages: 84-89
- DOI
  10.1016/j.bbrc.2023.08.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08161, KAKENHI-PROJECT-22K06945, KAKENHI-PROJECT-22K06962
[Journal Article] Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells.2022
- Author(s)
  Hirai S, Idogawa M, Sumi T, Yamaguchi M, Niki T, Sakuma Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 630 Pages: 24-29
- DOI
  10.1016/j.bbrc.2022.09.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06945, KAKENHI-PROJECT-22K06962, KAKENHI-PROJECT-19K08372
[Journal Article] CADM1 promotes malignant features of small-cell lung cancer by recruiting 4.1R to the plasma membrane2021
- Author(s)
  Funaki Toko、Ito Takeshi、Tanei Zen-ichi、Goto Akiteru、Niki Toshiro、Matsubara Daisuke、Murakami Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 172-178
- DOI
  10.1016/j.bbrc.2020.11.121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K07454, KAKENHI-PROJECT-18H02634, KAKENHI-PROJECT-20J12314, KAKENHI-PROJECT-19K16708, KAKENHI-PROJECT-20K21539, KAKENHI-PROJECT-20H03525
[Journal Article] BRG1, INI1, and ARID1B Deficiency in Endometrial Carcinoma2020
- Author(s)
  Kihara Atsushi、Amano Yusuke、Matsubara Daisuke、Fukushima Noriyoshi、Fujiwara Hiroyuki、Niki Toshiro
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 44 Issue: 12 Pages: 1712-1724
- DOI
  10.1097/pas.0000000000001581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10094, KAKENHI-PROJECT-19K16565, KAKENHI-PROJECT-18H02634
[Journal Article] EGFR-independent EGFR-mutant lung adenocarcinoma cells depend on Bcl-xL and MCL1 for survival.2020
- Author(s)
  Hirai S, Tada M, Yamaguchi M, Niki T, Sakuma Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 526 Pages: 417-423
- DOI
  10.1016/j.lungcan.2019.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02634
[Journal Article] Reciprocal expression of trefoil factor‐1 and thyroid transcription factor‐1 in lung adenocarcinomas2020
- Author(s)
  Matsubara Daisuke、Yoshimoto Taichiro、Soda Manabu、Amano Yusuke、Kihara Atsushi、Funaki Toko、Ito Takeshi、Sakuma Yuji、Shibano Tomoki、Endo Shunsuke、Hagiwara Koichi、Ishikawa Shumpei、Fukayama Masashi、Murakami Yoshinori、Mano Hiroyuki、Niki Toshiro
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 6 Pages: 1-13
- DOI
  10.1111/cas.14403
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K10094, KAKENHI-PROJECT-19K16565, KAKENHI-PROJECT-18H02634
[Journal Article] Trametinib downregulates survivin expression in RB1-positive KRAS-mutant lung adenocarcinoma cells.2018
- Author(s)
  Sumi T, Hirai S, Yamaguchi M, Tanaka Y, Tada M, Niki T, Takahashi H, Sakuma Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 501 Issue: 1 Pages: 253-258
- DOI
  10.1016/j.bbrc.2018.04.230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02634, KAKENHI-PROJECT-26293080
[Journal Article] Survivin knockdown induces senescence in TTF-1-expressing, KRAS-mutant lung adenocarcinomas.2018
- Author(s)
  Sumi T, Hirai S, Yamaguchi M, Tanaka Y, Tada M, Yamada G, Hasegawa T, Miyagi Y, Niki T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 33-46
- DOI
  10.3892/ijo.2018.4365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-16K19459, KAKENHI-PROJECT-18H02634
[Journal Article] Fibroblastic foci, covered with alveolar epithelia exhibiting epithelial-mesenchymal transition, destroy alveolar septa by disrupting blood flow in idiopathic pulmonary fibrosis.2017
- Author(s)
  Yamaguchi M, Hirai S, Tanaka Y, Sumi T, Miyajima M, Mishina T, Yamada G, Otsuka M, Hasegawa T, Kojima T, Niki T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 97 Pages: 232-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293080
[Journal Article] Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.2017
- Author(s)
  Matsubara D, Soda M, Yoshimoto T, Amano Y, Sakuma Y, Yamato A, Ueno T, Kojima S, Shibano T, Hosono Y, Kawazu M, Yamashita Y, Endo S, Hagiwara K, Fukayama M,Takahashi T, Mano H, Niki T.
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 9 Pages: 1888-1896
- DOI
  10.1111/cas.13313
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-17K07250, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H02468
[Journal Article] Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.2017
- Author(s)
  Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Tamura T, Oguni S, Katashiba S, Ito T, Murakami Y, Fukayama M, Murakami T, Endo S, Niki T.
- Journal Title
  
  Plos One
  
  Volume: 12 Issue: 8 Pages: e0181342-e0181342
- DOI
  10.1371/journal.pone.0181342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-17K16615, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26461700
[Journal Article] Loss of YAP1 defines neuroendocrine differentiation of lung tumors.2016
- Author(s)
  Ito T, Matsubara D, Tanaka I, Makiya K, Tanei ZI, Kumagai Y, Shiu SJ, Nakaoka HJ, Ishikawa S, Isagawa T, Morikawa T, Shinozaki-Ushiku A, Goto Y, Nakano T, Tsuchiya T, Tsubochi H, Komura D, Aburatani H, Dobashi Y, Nakajima J, Endo S, Fukayama M, Sekido Y, Niki T, Murakami Y.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 10 Pages: 1527-1538
- DOI
  10.1111/cas.13013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-26460438
[Journal Article] Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung adenocarcinoma cells with an epithelial-mesenchymal transition phenotype.2016
- Author(s)
  Sakuma Y, Nishikiori H, Hirai S, Yamaguchi M, Yamada G, Watanabe A, Hasegawa T, Kojima T, Niki T, Takahashi H.
- Journal Title
  
  Lab Invest.
  
  Volume: 96 Issue: 4 Pages: 391-398
- DOI
  10.1038/labinvest.2015.155
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-15K08364, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-15K08350
[Journal Article] Frequent loss of the expression of multiple subunits of the SWI/SNF complex in large cell carcinoma and pleomorphic carcinoma of the lung.2015
- Author(s)
  Yoshimoto T, Matsubara D, Nakano T, Tamura T, Endo S, Sugiyama Y, Niki T.
- Journal Title
  
  Pathology international
  
  Volume: 35 Issue: 11 Pages: 595-602
- DOI
  10.1111/pin.12350
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080
[Journal Article] The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma2015
- Author(s)
  Shin Saito, Kazue Morishima, Takashi Ui, Hiroko Hoshino, Daisuke Matsubara, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Yoshinori Hosoya, Naohiro Sato, Alan K Lefor, Yoshikazu Yasuda and Toshiro Niki
- Journal Title
  
  BMC cancer
  
  Volume: 15 Issue: 1 Pages: 1-12
- DOI
  10.1186/s12885-015-1065-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-25710020
[Journal Article] The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.2014
- Author(s)
  Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Ishikawa S, Aburatani H, Fukayama M, Niki T, Yasuda Y.
- Journal Title
  
  Oncol Rep.
  
  Volume: 31(2) Issue: 2 Pages: 619-24
- DOI
  10.3892/or.2013.2899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22134003, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080
[Journal Article] Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition.2014
- Author(s)
  Ibrahim R, Matsubara D, Osman W, Morikawa T, Goto A, Morita S, Ishikawa S, Aburatani H, Takai D, Nakajima J, Fukayama M, Niki T, Murakami Y
- Journal Title
  
  Hum Pathol.
  
  Volume: 45 Issue: 7 Pages: 1397-405
- DOI
  10.1016/j.humpath.2014.02.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460431, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26640121
[Journal Article] Stromal fibroblasts are predictors of disease-related mortality in esophageal squamous cell carcinoma.2014
- Author(s)
  Saito S, Morishima K, Ui T, Matsubara D, Tamura T, Oguni S, Hosoya Y, Sata N, Lefor AT, Yasuda Y, Niki T.
- Journal Title
  
  Oncology Reports
  
  Volume: 32 Issue: 1 Pages: 348-354
- DOI
  10.3892/or.2014.3216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080
[Journal Article] Immunohistochemical analysis of the expression of E-cadherin and ZEB1 in non-small cell lung cancer.2014
- Author(s)
  Matsubara D, Kishaba Y, Yoshimoto T, Sakuma Y, Sakatani T, Tamura T, Endo S, Sugiyama Y, Murakami Y, Niki T
- Journal Title
  
  Pathology International
  
  Volume: 64 Issue: 11 Pages: 560-568
- DOI
  10.1111/pin.12214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26640121
[Journal Article] Lung cancer with loss of BRG1?BRM,shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.2013
- Author(s)
  Matsubara D, Murakami Y, Niki T et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 2 Pages: 266-273
- DOI
  10.1111/cas.12065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300336, KAKENHI-PROJECT-23659189, KAKENHI-PROJECT-23790413, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25670178, KAKENHI-PLANNED-22134003
[Journal Article] Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells.2013
- Author(s)
  Sakuma Y, Matsukuma S, Nakamura Y, Yoshihara M, Koizume S, Sekiguchi H, Saito H, Nakayama H, Kameda Y, Yokose T, Oguni S, Niki T, and Miyagi Y.
- Journal Title
  
  Lab Invest.
  
  Volume: 93 Issue: 10 Pages: 1137-1146
- DOI
  10.1038/labinvest.2013.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501280, KAKENHI-PROJECT-24590440, KAKENHI-PROJECT-25670178
[Journal Article] Lung Cancer with Loss of BRG1/BRM, shows Epithelial Mesenchymal Transition Phenotype and Distinct Histologic and Genetic Features.2013
- Author(s)
  Matsubara D, Niki T (13thof 13)
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 266-273
- Data Source
  KAKENHI-PROJECT-23659189
[Journal Article] Identification of CCDC6-RET Fusion in the Human Lung Adenocarcinoma Cell Line2012
- Author(s)
  Matsubara D, Niki T (14thof 14)
- Journal Title
  
  LC-2/ad. J Thorac Oncol.
  
  Volume: 7 Pages: 1872-1876
- Data Source
  KAKENHI-PROJECT-23659189
[Journal Article] (Letter to the Editor) Epidermal Growth Factor Receptor Mutati on and Chemosensitivity2012
- Author(s)
  Matsubara D, Niki T
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Issue: 4 Pages: 771-772
- DOI
  10.1097/jto.0b013e318245a058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103, KAKENHI-PROJECT-23659189, KAKENHI-PROJECT-23790413
[Journal Article] Epidermal growth factor receptor mutation and chemosensitivity2012
- Author(s)
  Matsubara D, Niki T.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 4 Pages: 771-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Epidermal growth factor receptor mutation and chemosensitivity.2012
- Author(s)
  Matsubara D, Niki T
- Journal Title
  
  J Thorac Oncol
  
  Volume: 4 Pages: 771-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659189
[Journal Article] Lung Adenocarcinoma, Mixed Subtype : Histopathologic Basis for High-Resolution Computed Tomography Findings2011
- Author(s)
  Terasaki H, Niki T(5^<th> of 8)
- Journal Title
  
  J Thorac Imaging
  
  Volume: 26 Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Human papillomavirus infection in lung and esophageal cancers: Analysis of 485 Asian cases.2011
- Author(s)
  Goto A, Niki T (4thof 17)
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 1383-1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659189
[Journal Article] Human papillomavirus infection in lung and esophageal cancers : Analysis of 485 Asian cases2011
- Author(s)
  Goto A, Niki T
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 1383-1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Lung Adenocarcinoma, Mixed Subtype: Histopathologic Basis for High-Resolution Computed Tomography Findings.2011
- Author(s)
  Terasaki H, Niki T (5thof 8)
- Journal Title
  
  J Thorac Imaging
  
  Volume: 26 Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659189
[Journal Article] Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.2010
- Author(s)
  Matsubara D.Niki T, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 5 Pages: 1317-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas2010
- Author(s)
  Matsubara D, Niki T, et al
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Pages: 2191-2204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells2010
- Author(s)
  Matsubara D, Niki T, et al
- Journal Title
  
  J Thorac Oncol
  
  Volume: 5 Pages: 1317-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.2010
- Author(s)
  Matsubara D, Niki T, et al.
- Journal Title
  
  J Thorac Oncol 5
  
  Pages: 1317-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas.2010
- Author(s)
  Matsubara D.Niki T, et al.
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Pages: 2191-2204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas.2010
- Author(s)
  Matsubara D, Niki T, et al.
- Journal Title
  
  Am J Pathol 177
  
  Pages: 2191-2204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Subepithelial myofibroblast in lung adenocarcinoma : a histologic indicator of excellent prognosis2009
- Author(s)
  Matsubara D, Niki T, et al.
- Journal Title
  
  Mod Pathol 22
  
  Pages: 776-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Subepithelial myofibroblast in lung adenocarcinoma : a histologic indicator of excellent prognosis.2009
- Author(s)
  Matsubara D, Niki T, et al.
- Journal Title
  
  Mod Pathol 22
  
  Pages: 776-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Subepithelial myofibroblast in lung adenocarcinoma : a histologic indicator of excellent prognosis2009
- Author(s)
  Matsubara D, Niki T, et al
- Journal Title
  
  Mod Pathol
  
  Volume: 22 Pages: 776-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] AKR1B10 in usual interstitial pneumonia : Expression in squamous metaplasia in association with smoking and lung cancer2008
- Author(s)
  Li CP, Niki T
- Journal Title
  
  Pathol Res Pract
  
  Volume: 204 Pages: 295-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines2008
- Author(s)
  Nakamura Y, Niki T
- Journal Title
  
  Cancer Sci
  
  Volume: 99 Pages: 14-22
- NAID
  10024000720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers2008
- Author(s)
  Inamura K, Niki T
- Journal Title
  
  J Thorac Oncol
  
  Volume: 3 Pages: 13-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Journal Article] Frequent co-localization of cox-2 and laminin-5 g2 chain at the invasive front of early-stage lung adenocarcinoma.2002
- Author(s)
  Niki T, et al.
- Journal Title
  
  American Journal of Pathology 160
  
  Pages: 1129-1141
- Data Source
  KAKENHI-PROJECT-13218020
[Journal Article] Molecular predictors of sensitivity to the MET inhibitor PHA665 752 in lung carcinoma cells
- Author(s)
  Matsubara D, Niki T, et al.
- Journal Title
  
  J Thorac Oncol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] HNF familyの蛋白発現を認めた肺腺癌の一例2024
- Author(s)
  三浦珠希, 廣田由佳, 木原淳, 天野雄介, 松原大祐, 福嶋敬宣, 仁木利郎
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K06470
[Presentation] TTF-1陰性肺腺癌の臨床病理学的ならびに遺伝子的特徴について2023
- Author(s)
  三浦珠希, 木原淳, 天野雄介, 坪地宏嘉, 藤田一喬, 萩原弘一, 松原大祐, 福嶋敬宜, 仁木利郎
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K06470
[Presentation] HNF4a 陽性の高悪性度肺腺癌は、BRG1 欠失を高頻度に示す予後不良な一群である.2023
- Author(s)
  河合瞳, 三浦珠希, 川松夏実, 中川智貴, 柴綾, 石川俊平, 坪地宏嘉, 萩原弘一, 松原大祐, 仁木利郎.
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06945
[Presentation] TTF-1 陰性肺腺癌の臨床病理学的ならびに遺伝子的特徴について.2023
- Author(s)
  三浦珠希, 木原淳, 天野雄介, 坪地宏嘉, 藤田一喬, 萩原弘一, 松原大祐, 福嶋敬宜, 仁木　利郎.
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06945
[Presentation] Lung adenocarcinoma with features of malignant germ cell tumor: a case report.2022
- Author(s)
  Miura T, Niki T (10th of 10).
- Organizer
  第68回日本病理学会秋期特別総会学会
- Data Source
  KAKENHI-PROJECT-22K06945
[Presentation] MUC21 is a candidate key molecule involved in the incohesive growth pattern of lung adenocarcinoma.2018
- Author(s)
  Yoshimoto T, Matsubara D, Soda M, Amano Y, Kihara A, Nakano T, Shibano T, Endo S, Hagiwara K, Denda-Nagai K, Irimura T, Mano H, Niki T.
- Organizer
  6th JCA-AACR Special Joint Conference
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018
- Author(s)
  ３１．Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02634
[Presentation] Long-term, 3-dimensional spheroid culture: a putative model to study evolution of detached cancer cells in tumor metastasis.2018
- Author(s)
  Shibano T, nakano T, Kanai Y, Yoshimoto T, Amano Y, Matsubara D, Murakami T, Endo S, Niki T.
- Organizer
  17th Biennial Congress of Metastatic Research Society
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018
- Author(s)
  Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] 3D Low-Attachment Culture: A Putative Model for STAS And "Floating" Cancer Cells.2017
- Author(s)
  Nakano T, Yoshimoto T, Kanai Y, Shibano T, Matsubara D, Endo S, Niki T.
- Organizer
  18th World Conference of Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Mutation of SWI/SNF Complex Genes Is Frequent in Poorly Differentiated, Mesenchymal-Like Lung Cancer without Major Driver Mutation.2017
- Author(s)
  Yoshimoto T, Matsubara D, Niki T.
- Organizer
  18th World Conference of Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Establishment of Highly Metastatic Lung Cancer Cell Sublines in Long-term Three-dimensional Low Attachment Cultures.2017
- Author(s)
  Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Endo S, Niki T.
- Organizer
  18th World Conference of Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] 病理組織学的アプローチによるNon-TRUタイプ肺腺癌のNKX2-1遺伝子変異の同定2016
- Author(s)
  松原大祐、曽田学, 吉本多一郎, 天野雄介, 上野敏秀, 小島進也, 間野博行, 仁木利郎
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] 肺癌の上皮間葉転換におけるクロマチンリンモデリング因子異常の解析2016
- Author(s)
  吉本多一郎、松原大祐、福嶋敬宜、仁木利郎
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] 系統的肺腺癌ゼノグラフトを用いた癌間質相互作用の解析2016
- Author(s)
  吉本多一郎, 松原大祐, 河村大輔, 石川俊平, 仁木利郎
- Organizer
  第５７回日本肺癌学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県、福岡市）
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Altered expressions of multiple subunits of the switch/sucrose non-fermenting (SWI/SNF) complex in Non-small cell lung cancer.2015
- Author(s)
  Yoshimoto T, Matsubara D, Niki T.
- Organizer
  AACR special meeting
- Place of Presentation
  Atlanta
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] Altered expressions of multiple subunits of the switch/sucrose non-fermenting (SWI/SNF) complex in Non-small cell lung cancer.2015
- Author(s)
  Yoshimoto T, Matsubara D, Niki T.
- Organizer
  AACR special meeting
- Place of Presentation
  Atlanta
- Year and Date
  2015-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] CADM1陽性の高悪性度肺腺癌におけるRAPGEF2の役割．2015
- Author(s)
  許淑真，松原大祐，森川鉄平，中島淳，深山正久，仁木利郎，村上善則
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] 肺癌におけるYAP1 欠如と神経内分泌分化について2015
- Author(s)
  松原大祐，伊東剛，田中一大，石川俊平，後藤悌，中野智之，土橋洋，中島淳，遠藤俊輔，深山正久，関戸好孝，仁木利郎，村上善則
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] 肺癌におけるYAP1 欠如と神経内分泌分化について．2015
- Author(s)
  松原大祐，伊東剛，田中一大，石川俊平，後藤悌，中野智之，土橋洋，中島淳，遠藤俊輔，深山正久，関戸好孝，仁木利郎，村上善則．
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Molecular mechanisms for EMT in lung cancer; relationship with chromatin remodeling factors and mutation of EGFR.2013
- Author(s)
  Yoshimoto T, Niki T, Matsubara D.
- Organizer
  72th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] RET融合遺伝子を有する肺腺癌細胞株の発見2013
- Author(s)
  松原大祐、石川俊平、小原詩織、吉本多一郎、坂谷貴司、片岡寛章、村上善則、油谷浩幸、深山正久、仁木利郎．
- Organizer
  日本病理学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] KRAS 変異,EMT 形質を有する肺腺癌細胞の薬剤感受性2012
- Author(s)
  仁木利郎、松原大祐、石川俊平、A BC DAB深山正久
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 原発性肺腺癌におけるクロマチンリモデリング因子BRG1及びBRMの欠損と上皮間葉系転換との関連性について2012
- Author(s)
  仁木利郎
- Organizer
  日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 原発性肺腺癌におけるクロマチンリモデリング因子 BRG1 及び BRMの欠損と上皮間葉系転換との関連性について.2012
- Author(s)
  松原大祐、喜舎場由香、石川俊平、村上善則、油谷浩幸、深山正久、仁木利郎
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Histopathologic and genetic features of lung adenocarcinomas with loss of chromatin remodeling factors, BRG-1 and BRM.2012
- Author(s)
  Matsubara D, Niki T (5th of 5)
- Organizer
  Annual Meeting of American Association for Cancer Research (poster presentation)
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌における Snail の発現についての免疫組織学的検討2012
- Author(s)
  喜舎場由香, 松原大祐, 仁木利郎
- Organizer
  第101回日本病理学会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Histopathologic and genetic features of lung adenocarcinomas with loss of chromatin remodeling factors, BRG-1 and BRM2012
- Author(s)
  Matsubara D, Niki T
- Organizer
  Annual Meeting of American Association for Cancer Research(poster presentation)
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] KRAS変異，EMT形質を有する肺腺癌細胞の薬剤感受性．2012
- Author(s)
  仁木利郎
- Organizer
  日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌におけるSnail の発現についての免疫組織学的検討.2012
- Author(s)
  仁木利郎
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌におけるSnailの発現についての免疫組織学的検討2012
- Author(s)
  喜舎場由香, 松原大祐, 仁木利郎
- Organizer
  第101回日本病理学会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Expressions of bronchial epithelial markers correlate with morphology and genetic abnormalities in lung adenocarcinoma2011
- Author(s)
  Matsubara D, Niki T(4^<th> of 4)
- Organizer
  70th Annual Meeting of the Japanese Cancer Association(poster presentation)
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Expressions of bronchial epithelial markers correlate with morphology and genetic abnormalities in lung adenocarcinoma.2011
- Author(s)
  Matsubara D, Ishikawa S, Fukayama M, Niki T.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌細胞株の遺伝子発現データに基づく分類と、3次元培養下の細胞形態、遺伝子異常の関連性について2011
- Author(s)
  松原大祐, 石川俊平, 深山正久, 仁木利郎
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  東京,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture2011
- Author(s)
  Matsubara D, Ishikawa S, Fukayama M, Niki T
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 肺腺癌細胞株の遺伝子発現データに基づく分類と、3次元培養下の細胞形態、遺伝子異常との関連性について.2011
- Author(s)
  松原大祐, 石川俊平，深山正久，仁木利郎.
- Organizer
  第100回日本病理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture.2011
- Author(s)
  Matsubara D, Ishikawa S, Fukayama M, Niki T
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Three dimensional culture reveals genetic-morphologic correlations that may be relevant to classification of lung adenocarcinomas2011
- Author(s)
  Niki T, Matsubara D, Ishikawa S, Fukayama M.
- Organizer
  14th World Conference of Lung Cancer(poster presentation)
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 肺腺癌細胞株の遺伝子発現データに基づく分類と、 3 次元培養下の細胞形態、遺伝子異常の関連性について.2011
- Author(s)
  松原大祐,石川俊平,深山正久,仁木利郎
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  東京,ポスター発表
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌症例の気管支上皮マーカーの発現に基づく分類：組織学的形態、遺伝子異常、EGFR,METの活性化との関連.2011
- Author(s)
  松原大祐, 石川俊平，深山正久，仁木利郎.
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 肺腺癌細胞株の遺伝子発現データに基づく分類と、3次元培養下の細胞形態、遺伝子異常との関連性について2011
- Author(s)
  松原大祐, 石川俊平, 深山正久, 仁木利郎
- Organizer
  第100回日本病理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture.2011
- Author(s)
  Matsubara D, Niki T (4th of 4)
- Organizer
  Annual Meeting of American Association for Cancer Research (poster presentation)
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] 一般示説(病理):肺腺癌症例の気管支上皮マーカーの発現に基づく分類:組織学的形態、遺伝子異常、 EGFR,METの活性化との関連.2011
- Author(s)
  松原大祐, 石川俊平,深山正久,仁木利郎
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture2011
- Author(s)
  Matsubara D, Niki T(4^<th> of 4)
- Organizer
  Annual Meeting of American Association for Cancer Research(poster presentation)
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 一般示説(病理):肺腺癌症例の気管支上皮マーカーの発現に基づく分類:組織学的形態、遺伝子異常、EGFR, METの活性化との関連2011
- Author(s)
  松原大祐, 石川俊平, 深山正久, 仁木利郎
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Expressions of bronchial epithelial markers correlate with morphology and genetic abnormalities in lung adenocarcinoma2011
- Author(s)
  Matsubara D, Ishikawa S, Fukayama M, Niki T
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 肺腺癌症例の気管支上皮マーカーの発現に基づく分類:組織学的形態、遺伝子異常、EGFR,METの活性化との関連2011
- Author(s)
  松原大祐, 石川俊平, 深山正久, 仁木利郎
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Three dimensional culture reveals genetic-morphologic correlations that may be relevant to classification of lung adenocarcinomas.2011
- Author(s)
  Niki T, Matsubara D, Ishikawa S, Fukayama M
- Organizer
  14th World Conference of Lung Cancer (poster presentation)
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Expressions of bronchial epithelial markers correlate with morphology and genetic abnormalities in lung adenocarcinoma.2011
- Author(s)
  Matsubara D, Niki T (4th of 4)
- Organizer
  70th Annual Meeting of the Japanese Cancer Association (poster presentation)
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23659189
[Presentation] Classification of lung carcinoma cell lines by integrated information of EGFR and MET abnormalities and gene expression pattern correlated with reponse to chemotherapy and molecular targeted therapy2010
- Author(s)
  Matsubara D, Niki T(6^<th> of 6), et al
- Organizer
  Annual Meeting of American Association for Cancer Research(poster presentation)
- Place of Presentation
  Washington D. C
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] EGFR, METの活性化に基づく肺腺癌分類:予後因子, 薬剤感受性との関連2010
- Author(s)
  松原大祐、仁木利郎, 他
- Organizer
  第51回日本肺癌学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 3次元培養下の肺腺癌細胞株の集塊形成と遺伝子変異の関連性について2010
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 癌と創傷治癒-浸潤先進部の研究から考えたこと2010
- Author(s)
  仁木利郎
- Organizer
  第7回日本病理学会カンファランス
- Place of Presentation
  岡山
- Year and Date
  2010-08-07
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Cancer stroma of lung adenocarcinomas may differ in non-smokers and smokers2010
- Author(s)
  Kishaba Y, Matsubara D, Niki T.
- Organizer
  69th Annual Meeting of the Japanese Cancer Association(poster presentation)
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] EGFR, METの活性化に基づく肺腺癌分類:予後因子,薬剤感受性との関連について2010
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第51回日本肺癌学会総会
- Place of Presentation
  広島国際会議場,口演発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture2010
- Author(s)
  Matsubara D, Ishikawa S, Fukayama M, Niki T.
- Organizer
  69th Annual Meeting of the Japanese Cancer Association(poster presentation)
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分化マーカー, c-MET,ならびにEMT形質の発現による肺腺癌の分類と薬剤感受性との関連性2010
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Classification of lung carcinoma cell lines by integrated information of EGFR and MET abnormalities and gene expression pattern correlated with reponse to chemotherapy and molecular targeted therapy.2010
- Author(s)
  Matsubara D, Niki T, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington D.C (poster presentation)
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] EGFR, METの活性化に基づく肺腺癌分類:予後因子,薬剤感受性との関連について2010
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第51回日本肺癌学会総会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture2010
- Author(s)
  Matsubara D.Niki T, et al.
- Organizer
  69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Lung adenocarcinomas show genetic-morphologic correlations in three dimensional culture.2010
- Author(s)
  Matsubara D, Niki T, et al.
- Organizer
  69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka (poster presentation)
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Classification of lung carcinoma cell lines by integrated information of EGFR and MET abnormalities and gene expression pattern correlated with reponse to chemotherapy and molecular targeted therapy2010
- Author(s)
  Matsubara D.Niki T, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington D.C
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分化マーカー,c-MET,ならびにEMT形質の発現による肺腺癌の分類と薬剤感受性との関連性2010
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Copy number analysis for HER2 local amplification using PCR based detection2010
- Author(s)
  Sakatani T, Ishikawa S, Niki T, Fukayama M.
- Organizer
  69th Annual Meeting of the Japanese Cancer Association(poster presentation)
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 3次元培養での肺腺癌細胞の形態と遺伝子変異の相関について2009
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  新宿京王プラザホテル,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Predictors of sensitivities to MET inhibitor PHA665752 in lung adenocarcinoma cell lines2009
- Author(s)
  Matsubara D, Niki T, et al
- Organizer
  Annual Meeting of American Association for Cancer Research(poster presentation)
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分化マーカー(TTF-1, MUC1, CK7), MET,ならびにEMT(上皮間葉転換)形質の発現による肺腺癌の分類2009
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  新宿京王プラザホテル
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Predictors of sensitivities to MET inhibitor PHA665752 in lung adenocarcinoma cell lines.2009
- Author(s)
  Matsubara D, Niki T, et al.
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama (poster presentation)
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 3次元培養での肺腺癌細胞の形態と遺伝子変異の相関について2009
- Author(s)
  松原大祐, 仁木利郎, 他
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  東京
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分子標的セレクション:肺腺癌におけるMET阻害剤に対する感受性とMET, EGFR, KRASの遺伝子異常、リン酸化について2009
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  新宿京王プラザホテル,口演発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 肺腺癌におけるMET阻害剤に対する感受性とMET, EGFR, KRASの遺伝子異常、リン酸化について2009
- Author(s)
  松原大祐, 仁木利郎, 他
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  東京
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Predictors of sensitivities to MET inhibitor PHA665752 in lung adenocarcinoma cell lines2009
- Author(s)
  Matsubara D, Niki T, et al
- Organizer
  68th Annual Meeting of the Japanese Cancer Association(poster presentation)
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Predictors of sensitivities to MET inhibitor PHA665752 in lung adenocarcinoma cell lines.2009
- Author(s)
  Matsubara D, Niki T, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Denver (poster presentation)
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分化マーカー(TTF-1, MUC1, CK7), MET,ならびにEMT(上皮間葉転換)形質の発現による肺腺癌の分類2009
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  新宿京王プラザホテル,ポスター発表
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] 分子標的セレクション:肺腺癌におけるMET阻害剤に対する感受性とMET, EGFR, KRASの遺伝子異常、リン酸化について2009
- Author(s)
  松原大祐, 仁木利郎, ほか
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  新宿京王プラザホテル
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Classification of lung adenocarcinoma cell lines by gene expression profiles : relationships to EGFR mutation and MET amplification.2008
- Author(s)
  Matsubara D, Niki T, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego (poster presentation)
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] Classification of lung adenocarcinoma cell lines by gene expression profiles : relationships to EGFR mutation and MET amplification2008
- Author(s)
  Matsubara D, Niki T, et al
- Organizer
  Annual Meeting of American Association for Cancer Research(poster presentation)
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-20390103
[Presentation] The HSP90 inhibitor 17-AAG improves chemoresistance of cisplatin-resistant esophageal squamous cell　carcinoma cell lines.
- Author(s)
  Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Yasuda Y, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] The HSP90 inhibitor 17-AAG improves chemoresistance of cisplatin-resistant esophageal squamous cell　carcinoma cell lines.
- Author(s)
  ２５．Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Yasuda Y, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition.
- Author(s)
  Matsubara D, Ibrahim R, Osman W, Goto A, Morikawa T, Morita S, Ishikawa S, Aburatani H, Fukayama M, Niki T, Murakami Y.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25670178
[Presentation] Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition.
- Author(s)
  ２４．Matsubara D, Ibrahim R, Osman W, Goto A, Morikawa T, Morita S, Ishikawa S, Aburatani H, Fukayama M, Niki T, Murakami Y.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26293080

1. MATSYBARA Daisuk (80415554)

# of Collaborated Projects: 6 results

# of Collaborated Products: 92 results
2. YOSHIMOTO TAICHIRO (20634166)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. 佐久間裕司 (10364514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. OTA Satoshi (90324342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 深山正久 (70281293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 後藤明輝 (90317090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 萩原弘一 (00240705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 遠藤俊輔 (10245037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 天野雄介 (70571587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 三浦珠希 (50894565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 藤田一喬 (20887848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 坪地宏嘉 (50406055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 柴野智毅 (10648900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小林哲也 (40974499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMAGUCHI Miki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. KOIZUME Shiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 石川俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 村上善則

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 宮城洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 木原淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NIKI Toshiro 仁木 利郎

仁木 利郎 ニキ トシロウ

Research Projects

Research Products

Co-Researchers

Non-TRU type 肺腺癌を層別化するバイオマーカーならびに分子標的の同定

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生体内で可視化できる肺癌の超微小転移モデルの確立

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Analysis of the mechanisms of metastasis of lung adenocarcinoma by low-attachment spheroid culturePrincipal Investigator

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Integrated regulatory mechanism that govern differentiation and survival of driver-mutation-independent lung adenocarcinomaPrincipal Investigator

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Epigenetic abnormalities and reprogramming in epithelial-mesenchymal transition of lung adenocarcinomaPrincipal Investigator

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Systemic generation of metastatic models of lung adenocarcinomaPrincipal Investigator

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Identification of molecular target and its therapeutic application for micropapillary adenocarcinomaPrincipal Investigator

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Molecular targets for lung adenocarcinoma with epithelial-mesenchymal transition : identification and their application for diagnosis and therapy.Principal Investigator

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Investigation of genes induced at the invasive front of lung adenocarcinomasPrincipal Investigator

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Regulatory mechanisms for wound-related gene expression at invasive front of Lung adenocarcinomasPrincipal Investigator

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肺腺癌の診断,悪性度診断の客観化を目指した遺伝子診断システムの確立

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Cancer-Stromal Interaction in Lung AdenocarcinomaPrincipal Investigator

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[Book] 《標準臨床検査学》病理学・病理検査学2012

Author(s)

Total Pages

NIKI Toshiro 仁木利郎

仁木利郎ニキトシロウ