Sakuma Yuji 佐久間裕司

… Alternative Names

Researcher Number	10364514
Other IDs
Affiliation (Current)	2020: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2014 – 2020: 札幌医科大学, 医学部, 准教授 2013: 自治医科大学, 医学部, 講師 2012: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), がん分子病態学部, 副技幹 2011: 地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター(臨床研究所)・がん分子病態学部, 副技幹 2011: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究部), がん分子病態学部, 副技幹 … More
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related Except Principal Investigator Biological Sciences / Human pathology / Tumor therapeutics / Respiratory organ internal medicine / Basic Section 49020:Human pathology-related / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 肺腺癌 / EGFR遺伝子変異 / アポトーシス / EGFR / 小型肺腺癌 / 術後再発 / 予後予測式 / 脈管浸潤 / 転移 / Src … More Except Principal Investigator GIST / c-kit / EGFR / メチル化 / 肺腺癌 / モノクローナル抗体 / microscopic / CGH / microarray / LOH / 顕微鏡的 / 発生頻度 / 病理解剖 / imatinib治療 / KIT陰性化 / PDGFRB / Met / RTKs inhibitor / マイクロアレイ / 分子標的治療 / 上皮間葉転換 / エピジェネティックス / 分化形質 / 肺癌 / エピジェネティクス / EGFR阻害薬耐性細胞株 / ADC型抗体薬 / 抗体スクリーニング / 内在化 / EGFR阻害薬耐性 / 抗体結合型トキシンタンパク質 / DT3C / 肺サーファクタント蛋白質D / 変異型EGFR / 肺がん / 糖鎖 / レクチン / 肺サーファクタントタンパク質 / EGFR遺伝子変異 / 肺サーファクタント蛋白質 / 肺サーファクタント / 肺コレクチン / SP-D / 分子標的 / 細胞分化 / 病理組織 / 肺上皮幹細胞 / 選択的培養法 / イミュノトキシン / 抗体 / 高性能イミュノトキシン / 肺上皮前駆/幹細胞 / 選択的な培養 / 特発性肺線維症の治療 Less

Pericytes play a critical role in the development of idiopathic pulmonary fibrosisPrincipal InvestigatorOngoing
- Principal Investigator
  
  佐久間裕司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University
Integrated regulatory mechanism that govern differentiation and survival of driver-mutation-independent lung adenocarcinomaOngoing
- Principal Investigator
  
  仁木利郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Jichi Medical University
Development of a selective culture method for pulmonary epithelial stem cells using high-performance immunotoxinOngoing
- Principal Investigator
  
  山口美樹
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Sapporo Medical University
Surfactant protein D inhibits activation of non-small cell lung cancer-associated mutant EGFR
- Principal Investigator
  
  Hasegawa Yoshihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sapporo Medical University
Generation of immunotoxins with super-targeting mAb in the EGFR-mutant lung adenocarcinoma
- Principal Investigator
  
  YAMAGUCHI MIKI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
Integrative analyses of lung adenocarcinomas that have undergone epithelial to mesenchymal transition (EMT) and those that retain an epithelial phenotypePrincipal Investigator
- Principal Investigator
  
  Sakuma Yuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
Epigenetic abnormalities and reprogramming in epithelial-mesenchymal transition of lung adenocarcinoma
- Principal Investigator
  
  Niki Toshiro
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
Identification of molecular mechanisms other than genetic abnormalities in EGFR-TKI resistance of lung adenocarcinomasPrincipal Investigator
- Principal Investigator
  
  SAKUMA Yuji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
  Jichi Medical University
  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所)
肺腺癌の転移成立を防ぐための研究Principal Investigator
- Principal Investigator
  
  SAKUMA Yuji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  地方独立行政法人神奈川県立病院機構
   Kanagawa Cancer Center Research Institute
GISTの発生、顕性化、悪性化に関与する遺伝子異常の解明
- Principal Investigator
  
  櫻井信司
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Development of a logistic regression predictive model for the outcome of patients with resected lung adenocarcinoma of 2cm or less in sizePrincipal Investigator
- Principal Investigator
  
  SAKUMA Yuji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kanagawa Cancer Center Research Institute
真のGISTの発生頻度と、その顕性化、悪性化に関与する遺伝子異常
- Principal Investigator
  
  櫻井信司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University

All 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Trametinib downregulates survivin expression in RB1-positive KRAS-mutant lung adenocarcinoma cells.2018
- Author(s)
  Sumi T, Hirai S, Yamaguchi M, Tanaka Y, Tada M, Niki T, Takahashi H, Sakuma Y.
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 501 Pages: 253-258
- DOI
  10.1016/j.bbrc.2018.04.230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02634, KAKENHI-PROJECT-26293080
[Journal Article] Characterization of distal airway stem-like cells expressing N-terminally truncated p63 and thyroid transcription factor-1 in the human lung2018
- Author(s)
  Tanaka Y, Yamaguchi M, Hirai S, Sumi T, Tada M, Saito A, Chiba H, Kojima T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  Experimental Cell Research
  
  Volume: 372(2) Pages: 141-149
- DOI
  10.1016/j.yexcr.2018.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08151, KAKENHI-PROJECT-18K15956, KAKENHI-PROJECT-17K16053
[Journal Article] Survivin knockdown induces senescence in TTF-expressing, KRAS-mutant lung adenocarcinomas.2018
- Author(s)
  Sumi T, Hirai S, Yamaguchi M, Tanaka Y, Tada M, Yamada G, Hasegawa T, Miyagi Y, Niki T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  INTERNATIONAL JOURNAL OF ONCOLOGY
  
  Volume: 52 Pages: 33-46
- DOI
  10.3892/ijo.2018.4365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-16K19459, KAKENHI-PROJECT-18H02634
[Journal Article] Angiotensin-converting enzyme 2 is a potential therapeutic target for EGFR-mutant lung adenocarcinoma2017
- Author(s)
  Yamaguchi M, Hirai S, Sumi T, Tanaka Y, Tada M, Nishii Y, Hasegawa T, Uchida H, Yamada G, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 487(3) Pages: 613-618
- DOI
  10.1016/j.bbrc.2017.04.102
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-15K08364
[Journal Article] Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas2017
- Author(s)
  Matsubara D, Soda M, Yoshimoto T, Amano Y, Sakuma Y, Yamato A, Ueno T, Kojima S, Shibano T, Hosono Y, Kawazu M, Yamashita Y, Endo S, Hagiwara K, Fukayama M, Takahashi T, Mano H, Niki T
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 9 Pages: 1888-1896
- DOI
  10.1111/cas.13313
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-17K07250, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H02468
[Journal Article] Surfactant protein D inhibits activation of non-small cell lung cancer-associated mutant EGFR and affects clinical outcomes of patients.2017
- Author(s)
  Umeda Y、Hasegawa Y、Otsuka M、Ariki S、Takamiya R、Saito A、Uehara Y、Saijo H、Kuronuma K、Chiba H、Ohnishi H、Sakuma Y、Takahashi H、Kuroki Y、Takahashi M
- Journal Title
  
  Oncogene.
  
  Volume: 36 Pages: 6432-6445
- DOI
  10.1038/onc.2017.253
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461
[Journal Article] Fibroblastic foci, covered with alveolar epithelia exhibiting epithelial-mesenchymal transition, destroy alveolar septa by disrupting blood flow in idiopathic pulmonary fibrosis2017
- Author(s)
  Yamaguchi M, Hirai S, Tanaka Y, Sumi T, Miyajima M, Mishina T, Yamada G, Otsuka M, Hasegawa T, Kojima T, Niki T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  Lab Invest
  
  Volume: Mar;97(3) Pages: 232-242
- DOI
  10.1038/labinvest.2016.135
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-15K08364
[Journal Article] Fibroblastic foci, covered with alveolar epithelia exhibiting epithelial-mesenchymal transition, destroy alveolar septa by disrupting blood flow in idiopathic pulmonary fibrosis.2017
- Author(s)
  Yamaguchi M, Hirai S, Tanaka Y, Sumi T, Miyajima M, Mishina T, Yamada G, Otsuka M, Hasegawa T, Kojima T, Niki T, Watanabe A, Takahashi H, Sakuma Y.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 97 Pages: 232-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293080
[Journal Article] Surfactant protein A downregulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D2017
- Author(s)
  Yoshihiro Hasegawa, Motoko Takahashi, Shigeru Ariki, Atsushi Saito, Yasuaki Uehara, Rina Takamiya, Koji Kuronuma, Hirofumi Chiba, Yuji Sakuma, Hiroki Takahashi, Yoshio Kuroki
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Pages: 18565-18565
- DOI
  10.1074/jbc.m117.800771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461
[Journal Article] Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung adenocarcinoma cells with an epithelial-mesenchymal transition phenotype.2016
- Author(s)
  Sakuma Y, Nishikiori H, Hirai S, Yamaguchi M, Yamada G, Watanabe A, Hasegawa T, Kojima T, Niki T, Takahashi H.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 96 Pages: 391-398
- DOI
  10.1038/labinvest.2015.155
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-15K08364, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-15K08350
[Journal Article] The Hsp 90 inhibitor, 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.2014
- Author(s)
  Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Ishikawa S, Aburatani H, Fukayama M, Niki T, Yasuda Y.
- Journal Title
  
  Oncol Rep
  
  Volume: 31(2) Pages: 619-24
- DOI
  10.3892/or.2013.2899
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22134003, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080
[Journal Article] Immunohistochemical analysis of the expression of E-cadherin and ZEB1 in non-small cell lung cancer.2014
- Author(s)
  Matsubara D, Kishaba Y, Yoshimoto T, Sakuma Y, Sakatani T, Tamura T, Endo S, Sugiyama Y, Murakami Y, Niki T
- Journal Title
  
  Pathol Int
  
  Volume: 64 Pages: 560-568
- DOI
  10.1111/pin.12214
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-25670178, KAKENHI-PROJECT-26293080, KAKENHI-PROJECT-26640121
[Journal Article] Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells.2013
- Author(s)
  Sakuma Y, Matsukuma S, Nakamura Y, Yoshihara M, Koizume S, Sekiguchi H, Saito H, Nakayama H, Kameda Y, Yokose T, Oguni S, Niki T, and Miyagi Y
- Journal Title
  
  Lavoratory Investigation
  
  Volume: 93 Pages: 1137-1146
- DOI
  10.1038/labinvest.2013.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501280, KAKENHI-PROJECT-24590440, KAKENHI-PROJECT-25670178
[Journal Article] WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors2012
- Author(s)
  Sakuma Y, Yamazaki Y, Nakamura Y, Yoshihara M, Matsukuma S, Nakayama H, Yokose T, Kameda Y, Koizume S, Miyagi Y.
- Journal Title
  
  Lab Invest
  
  Volume: 92 Pages: 371-383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790367
[Journal Article] WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors2012
- Author(s)
  Sakuma Y, et al
- Journal Title
  
  Lab. Invest.
  
  Volume: 92 Pages: 371-383
- DOI
  10.1038/labinvest.2011.187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790367, KAKENHI-PROJECT-23501280
[Journal Article] NF-κB signaling is activated and confers resistance to apoptosis in three-dimensionally cultured EGFR-mutant lung adenocarcinoma cells.2012
- Author(s)
  Sakuma Y, Yamazaki Y, Nakamura Y, Yoshihara M, Matsukuma S, Koizume S, and Miyagi Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423 Pages: 667-671
- DOI
  10.1016/j.bbrc.2012.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501280, KAKENHI-PROJECT-24590440
[Journal Article] ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis2011
- Author(s)
  Sakuma Y, vTsunezumi J, Nakamura Y, Yoshihara M, Matsukuma S, Koizume S, Miyagi Y.
- Journal Title
  
  Oncol Rep
  
  Volume: 25 Pages: 661-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790367
[Journal Article] ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis2011
- Author(s)
  Sakuma Y, et al
- Journal Title
  
  Oncology Report
  
  Volume: 25 Pages: 661-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790367
[Journal Article] Lung adenocarcinoma cells floating in lymphatic vessels resist anoikis by expressing phosphorylated Src2010
- Author(s)
  Sakuma Y, et al.
- Journal Title
  
  The Journal of Pathology 220
  
  Pages: 574-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790294
[Journal Article] Lung adenocarcinoma cells floating in lymphatic vessels resist anoikis by expressing phosphorylated2010
- Author(s)
  Sakuma Y, Takeuchi T, Nakamura Y, Yoshihara M, Matsukuma S, Nakayama H, Ohgane N, Yokose T, Kameda Y, Tsuchiya E, Miyagi Y.
- Journal Title
  
  J Pathol 220
  
  Pages: 574-585
- Data Source
  KAKENHI-PROJECT-20790294
[Journal Article] A logistic regression predictive model and the outcome of patients with resected lung adenocarcinoma of 2cm or less in size.2009
- Author(s)
  Sakuma Y, Okamoto N, Saito H, Yamada K, Yokose T, Kiyoshima M, Asato Y, Amemiya R, Saitoh H, Matsukuma S, Yoshihara M, Nakamura Y, Oshita F, Ito H, Nakayama H, Kameda Y, Tsuchiya E, Miyagi Y.
- Journal Title
  
  Lung Cancer 65
  
  Pages: 85-90
- Data Source
  KAKENHI-PROJECT-20790294
[Journal Article] A logistic regression predictive model and the outcome of patients with resected lung adenocarcinoma of 2cm or less in size2009
- Author(s)
  Sakuma Y, et al.
- Journal Title
  
  Lung Cancer 65
  
  Pages: 85-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790294
[Journal Article] Mutations of c-kit gene in bilateral testicular germ cell tumours in Japan.2008
- Author(s)
  Sakuma Y, Matsukuma S, et. al.
- Journal Title
  
  Cancer Letter 259
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18014006
[Journal Article] High incidence of microscopic gastrointestinal stromal tumors in the stomach.2006
- Author(s)
  Kawanowa K, Sakuma Y, Sakurai S et al.
- Journal Title
  
  Human Pathology 37・12
  
  Pages: 1527-1535
- Data Source
  KAKENHI-PROJECT-18014006
[Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018
- Author(s)
  ３１．Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02634
[Presentation] Reciprocal expressions of TFF-1 and TTF-1 in lung adenocarcinomas.2018
- Author(s)
  Matsubara D, Soda M, Yoshimoto T, Amano Y, Kihara A, Sakuma Y, Endo S, Hagiwara K, Fukayama M, Mano H, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] 肺サーファクタント蛋白質Dによる変異型EGFRの制御機構2016
- Author(s)
  長谷川喜弘, 佐久間裕司, 高橋素子
- Organizer
  第75回日本癌学会学術総会, 2016年10月6日～8日
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19461
[Presentation] EGFR変異陽性肺腺癌と特発性肺線維症の分子細胞病理学2016
- Author(s)
  佐久間裕司
- Organizer
  第62回日本病理学会秋期特別総会
- Place of Presentation
  金沢市文化ホール（石川県金沢市）
- Year and Date
  2016-11-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K08364
[Presentation] Isomerase Pin1 promotes survival in EGFR mutant lung adenocarcinoma c ells with an EMT phenotype2016
- Author(s)
  佐久間裕司、長谷川　匡、仁木利郎
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K08364
[Presentation] EGFR-mutant lung adenocarcinoma cells depend critically on EGFR activation to thrive in anchorage-independent conditions2011
- Author(s)
  Sakuma Y, Nakamura Y, Yoshihara M, Koizume S, Miyagi Y
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋・名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22790367
[Presentation] 肺腺癌におけるanoikis抵抗性の研究2011
- Author(s)
  佐久間裕司、中村圭靖、横瀬智之、亀田陽一、宮城洋平
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22790367
[Presentation] ABT-263 enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis2010
- Author(s)
  Sakuma Y, Nakamura Y, Yoshihara M, Koizume S, Miyagi Y.
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪・大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790367
[Presentation] Lung adenocarcinoma cells floating in lymphatic vessels resist anoikis by expressing Src.2009
- Author(s)
  Sakuma Y, Takeuchi T, Nakamura Y, Yoshihara M, Matsukuma S, Yokose T, Kameda Y, Tsuchiya E, Miyagi Y.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20790294
[Presentation] Lung adenocarcinoma cells floating in lymphatic vessels resist anoikis by expressing Src2009
- Author(s)
  Sakuma Y, et al.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20790294
[Presentation] 予後不良の小型肺腺癌の特徴を明らかにするための研究2008
- Author(s)
  佐久間裕司、中村圭靖、亀田陽一、横瀬智之、土屋永寿、宮城洋平
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-20790294
[Presentation] Mutations of c-kit gene in bilateral testicular germ cell tumors in Japan2007
- Author(s)
  佐久間裕司、松隈章一, 他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18014006
[Presentation] The HSP90 inhibitor 17-AAG improves chemoresistance of cisplatin-resistant esophageal squamous cell　carcinoma cell lines.
- Author(s)
  ２５．Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Yasuda Y, Niki T.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26293080
[Presentation] EGFR遺伝子変異陽性肺癌に内在するZEB1発現細胞の研究
- Author(s)
  佐久間裕司、仁木利郎
- Organizer
  第55回日本肺癌学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24590440
[Presentation] EGFR遺伝子変異陽性肺腺癌におけるautophagyの役割の解明
- Author(s)
  ２．佐久間裕司、中村圭靖、横瀬智之、亀田陽一、宮城洋平
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌・ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24590440
[Presentation] 細胞外基質との接着が誘導するEGFR遺伝子変異陽性肺腺癌細胞のapoptosis抵抗性の研究
- Author(s)
  佐久間裕司、中村圭靖、横瀬智之、亀田陽一、宮城洋平
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京・京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24590440

1. YAMAGUCHI MIKI (10530454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. Niki Toshiro (90198424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 櫻井信司 (00285769)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 吉本多一郎 (20634166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 松原大祐 (80415554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 内田宏昭 (20401250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. Hasegawa Yoshihiro (90643180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. TAKAHASHI MOTOKO (00303941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. TAKAHASHI HIROKI (60231396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 西井ゆかり (10619505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 萩原弘一 (00240705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 遠藤俊輔 (10245037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 角俊行 (60772291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 田中悠祐 (70792125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 多田周 (00815441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. TAKAMIYA Rina

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. HIRAI sachie

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. SAITO atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. CHIBA hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. KOJIMA takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. WATANABE atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. YAMADA gen

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. HASEGAWA tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. MIYAGI yohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
25. KOIZUME Shiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 高橋隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 鈴木康司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 齋藤充史

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. 石川俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 村上善則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakuma Yuji 佐久間 裕司

SAKUMA Yuji 佐久間 裕司

Research Projects

Research Products

Co-Researchers

Pericytes play a critical role in the development of idiopathic pulmonary fibrosisPrincipal InvestigatorOngoing

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Integrated regulatory mechanism that govern differentiation and survival of driver-mutation-independent lung adenocarcinomaOngoing

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Development of a selective culture method for pulmonary epithelial stem cells using high-performance immunotoxinOngoing

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Surfactant protein D inhibits activation of non-small cell lung cancer-associated mutant EGFR

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Generation of immunotoxins with super-targeting mAb in the EGFR-mutant lung adenocarcinoma

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Integrative analyses of lung adenocarcinomas that have undergone epithelial to mesenchymal transition (EMT) and those that retain an epithelial phenotypePrincipal Investigator

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Epigenetic abnormalities and reprogramming in epithelial-mesenchymal transition of lung adenocarcinoma

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Identification of molecular mechanisms other than genetic abnormalities in EGFR-TKI resistance of lung adenocarcinomasPrincipal Investigator

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肺腺癌の転移成立を防ぐための研究Principal Investigator

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GISTの発生、顕性化、悪性化に関与する遺伝子異常の解明

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Development of a logistic regression predictive model for the outcome of patients with resected lung adenocarcinoma of 2cm or less in sizePrincipal Investigator

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真のGISTの発生頻度と、その顕性化、悪性化に関与する遺伝子異常

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[Journal Article] Trametinib downregulates survivin expression in RB1-positive KRAS-mutant lung adenocarcinoma cells.2018

Author(s)

Journal Title

Sakuma Yuji 佐久間裕司

SAKUMA Yuji 佐久間裕司