Arimoto Sakae 有元佐賀惠

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ARIMOTO Sakae 有元佐賀惠

KOBAYASHI Sakae 小林佐賀恵

KOBAYASHI-ARIMOTO Sakae 小林佐賀惠

有元佐賀惠アリモトサカエ

有元佐賀恵アリモトサカエ

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Researcher Number	90212654
Other IDs
Affiliation (based on the past Project Information) *help	2021: 岡山大学, 医歯薬学域, 准教授 2016 – 2020: 岡山大学, 医歯薬学総合研究科, 准教授 2015: 岡山大学, 医歯(薬)学総合研究科, 准教授 2011 – 2013: 岡山大学, 医歯(薬)学総合研究科, 准教授 2009 – 2010: Okayama University, 大学院・医歯薬学総合研究科, 准教授 … More 2008: Okayama University, 大学院・医歯学総合研究科, 准教授 2005: 岡山大学, 大学院・医歯薬学総合研究科, 助教授 2005: OKAYAMA UNIVERSITY, Graduate school of Medicine, Dentistry and Pharmaceutical Sciences, Associate professor, 大学院医歯薬学総合研究科, 助教授 2001 – 2004: 岡山大学, 薬学部, 助教授 1998 – 2001: 岡山大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals / Environmental pharmacy / Biological pharmacy Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Bacteriology (including Mycology) / Biological pharmacy / Eating habits, studies on eating habits
Keywords	Principal Investigator 一酸化窒素 / ニトロソプロリン / DNA傷害 / 光毒性 / 近紫外光 / 酸化的DNA傷害 / 8-ハイドロキシグアニン / 光遺伝毒性 / DNA付加体 / 光活性化 … More / DNA損傷 / タバコ副流煙 / N-ニトロサミン / 変異スペクトラム / cGMP / NOラジカル / 光反応機構 / 活性酸素種 / ヒト由来表皮角化細胞 / N-ニトロソモルホリン / N-ニトロソピロリジン / DNA付加体形成 / N-ニトロソプロリン / Oxidative DNA damage / DNA alkylation / Nitrosoproline / Deoxyguanosine adducts / DNA damage / Nitric oxide / N-nitroso compound / Ultraviolet light / マウス皮膚2段階発がん実験 / マウス皮膚2段階発癌実験 / タバコ特異的ニトロソアミン / DNAアルキル化 / デオキシグアノシン付加体 / N-ニトロソ化合物 / PHOTO TOXICITY / 8-OXODEOXYGUANOSINE / ACTIVE OXYGEN / NITRIC OXIDE / DNA BREAKAGE / MUTATION / ULTRAVIOLET-A / NITROSOPROLINE / 遺伝子損傷 / ニトロソ化 / ヒト由来細胞 / 太陽光 / 変異原性 / ニトロソ化アミノ酸 / 活性酸素 / DNA切断 / 突然変異 / Alkylative agent / Heterocyclic amine / Instrumental analysis / Highly sensitive analysis / DNA adducts / Carcinogens / アルキル化剤 / ヘテロサイクリックアミン / 機器分析 / 高感度分析 / 発がん物質 / ヒトケラチノサイト / ヌクレオチド付加体 / 8-オキソグアニン / 光化学反応 / 小核形成 / 遺伝毒性 / アルキルラジカル / UVA / デオキシキサントシン / デオキシオキザノシン / デオキシイノシン / 8-オキソデオキシグアノシン / DNA修飾 / ニトロソチロシン / 光変異原性 / アミノ酸修飾 … More Except Principal Investigator ATPase / ATP / ADP / DnaA / 発がんリスク / 変異原性 / 口腔細菌 / Diarrhea / Hemolysin / Membrane protein / Maturation / Secretion / Aeromonas spp. / Escherichia coli / Enterotoxin / プロテアーゼ / グラム陰性菌 / 膜 / 菌体外毒素 / 蛋白分解酵素 / 細胞膜 / 毒素 / 成熟化 / 下痢 / 溶血毒 / 膜タンパク質 / 成熟 / 分泌 / アエロモナス菌 / 大腸菌 / エンテロトキシン / regulation of activity / DNA replication / Cdc6p / ATP結合 / 開始因子 / 癌 / 結晶構造解析 / 機能ドメイン / 酸性リン脂質 / ORC / リン脂質 / 活性調節 / DNA複製 / MS分析 / LC-MS / 変異原物質 / DNA損傷 Less

Survay on carcinogenic risks by oral bacteria and their measures
- Principal Investigator
  
  Kokeguchi Susumu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Okayama University
Analysis of photochemical activation of endogenic and environmental N-nitrosamines and its photogenotoxicity and disturbance on cell functionsPrincipal Investigator
- Principal Investigator
  
  Arimoto Sakae
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Okayama University
UVA activated N-nitrosoproline induced damages on DNA, protein and membrane, and disturbance of signal transductionPrincipal Investigator
- Principal Investigator
  
  ARIMOTO Sakae
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Okayama University
塩蔵食品由来変異原2-クロロ-4-メチルチオ酪酸によるDNA損傷に関する研究
- Principal Investigator
  
  木村幸子
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Hyogo
DNA and protein modification and disturbance on cell system with NO produced from photo-reactivation of N-nitrosated amino acidsPrincipal Investigator
- Principal Investigator
  
  ARIMOTO Sakae
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Okayama University
Reaction mechanisms and evaluation of toxicity of the formation of nitric oxide from UVA-irradiated N-nitroso-compoundPrincipal Investigator
- Principal Investigator
  
  ARIMOTO Sakae
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  OKAYAMA UNIVERSITY
Studies on the secretion and maturation pathway of bacterial exotoxin
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKAYAMA UNIVERSITY
Tne initiator of chromosomal DNA replication in E. coli.
- Principal Investigator
  
  TSUCHIYA Tomofusa, KURODA Teruo
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
GENETIC DAMAGES IN DNA EXPOSED N-NITROSO AMINO ACIDS WITH UVA RADIATIONPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI-ARIMOTO Sakae
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Okayama University
Development of analytical methods for DNA-carcinogen adductsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Sakae
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY

[Journal Article] Antimutagenic, anti-inflammatory, and antioxidative activities of the juice of Vitis ficifolia var. Ganebu, a woody vine in the grape family, known as Ryukyu-ganebu in Japan2021
- Author(s)
  Arimoto-Kobayashi S, Hida R, Fujii N, Mochioka R.
- Journal Title
  
  Genes Environ.
  
  Volume: 43(1) Issue: 1 Pages: 50-59
- DOI
  10.1186/s41021-021-00225-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10087
[Journal Article] Isolation and identification of photoproducts from UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine2019
- Author(s)
  Shuhei Aoyama, Chiharu Asahi, Kayoko Sano, Sachiko Kimura, Toshinori Suzuki, Tsutomu Hatano, Sakae Arimoto-Kobayashi
- Journal Title
  
  Journal of Photochemistry and Photobiology A: Chemistry
  
  Volume: 377 Pages: 159-166
- DOI
  10.1016/j.jphotochem.2019.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00556
[Journal Article] Mutation spectrum resulting in M13mp2 phage DNA exposed to N -nitrosoproline with UVA irradiation2017
- Author(s)
  Horai Yumi、Ando Yoshiko、Kimura Sachiko、Arimoto-Kobayashi Sakae
- Journal Title
  
  Mutation Research
  
  Volume: 821 Pages: 1-4
- DOI
  10.1016/j.mrgentox.2017.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00556
[Journal Article] Mutagenicity and NO Formation from UVA Irradiated <i>N</i>-Nitrosoproline, and Characterization of Photoproduct Formed in UVA-irradiated Mixture of <i>N</i>-Nitrosoproline with 2′-Deoxyguanosine in Neutral Solution2014
- Author(s)
  Arimoto-Kobayashi, S., Machida, M., Sano, K., Aoyama, S., Asahi, C., Tanaka, N., Okamoto, K., Negishi, T., Kimura, S. and Suzuki, T
- Journal Title
  
  Genes and Environment
  
  Volume: 36 Issue: 2 Pages: 47-53
- DOI
  10.3123/jemsge.2014.004
- NAID
  130004943659
- ISSN
  1880-7046, 1880-7062
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510075
[Journal Article] Near ultraviolet radiation-mediated reaction between N-nitrosoproline and DNA: Isolation and identificatio of two new adducts, (R)- and (S)-8-(2-pyrrolidyl)-2’-deoxyguanosine2013
- Author(s)
  Aoyama, S., Sano, K., Asahi, C., Machida, M., Okamoto, K., Negishi, T, Kimura, S., Suzuki, T., Hatano, T., Arimoto-Kobayashi, S.
- Journal Title
  
  J. Photochem. Photobilo. A: Chemistry
  
  Volume: 276 Pages: 1-7
- DOI
  10.1016/j.jphotochem.2013.11.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510063, KAKENHI-PROJECT-23510075
[Journal Article] Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells2011
- Author(s)
  Mayumi Horinouchi、Sakae Arimoto-Kobayashi
- Journal Title
  
  Mutation Research
  
  Volume: Vol.725 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells2011
- Author(s)
  Mayumi Horinouchi, Sakae Arimoto-Kobayashi
- Journal Title
  
  Mutation Research
  
  Volume: 725 Issue: 1 Pages: 43-50
- DOI
  10.1016/j.mrgentox.2011.04.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510075
[Journal Article] Nitrosation of Glutathione and Nitration of Tyrosine by N-Nitrosoproline with Ultraviolet Light2010
- Author(s)
  Atsushi Naka, Toshinori Suzuki, Sakae Arimoto-Kobayashi
- Journal Title
  
  Genes and Environment
  
  Volume: 32 Pages: 75-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] Nitrosation of Glutathione and Nitration of Tyrosine byN-Nitrosoproline with Ultraviolet Light2010
- Author(s)
  Atsushi Naka、Toshinori Suzuki、Sakae Arimoto-Kobayashi
- Journal Title
  
  Genes and Environment
  
  Volume: Vol.32 Pages: 75-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test2010
- Author(s)
  Sakae Arimoto-Kobayashi、Kayoko Sano, Masaki Machida、Keiko Kaji、Keiko Yakushi
- Journal Title
  
  Mutation Research
  
  Volume: Vol.691 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test2010
- Author(s)
  Sakae Arimoto-Kobayashi, Kayoko Sano, Masaki Machida, Keiko Kaji, Keiko Yakushi
- Journal Title
  
  Mutation Research
  
  Volume: 691 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] Copper phthalocyanine sulfonate-mediated oxidative degradation of 3-hydroxyamino-1-methyl-5H-pyrido[4, 3-b] indole(Trp-P-2(NHOH)), a direct-acting mutagen derived from Trp-P-2 by metabolic activation2009
- Author(s)
  Mayumi Horinouchi、Sakae Arimoto-Kobayashi
- Journal Title
  
  Genes and Environment
  
  Volume: Vol.31 Pages: 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510064
[Journal Article] A possible photosensitizer : tobacco-specific nitrosamine, 4-(N-methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), induced mutations, DNA strand breaks and oxidative and methylative damage With UVA.2007
- Author(s)
  Arimoto-Kobayashi, S. 他3名
- Journal Title
  
  Mutation Research (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Inhibitory effects of beer on mutation in the Ames test and DNA adduct formation in mouse organs induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).2006
- Author(s)
  Arimoto-Kobayashi, S.他8名
- Journal Title
  
  Biological Pharmaceutical Bulletin 29
  
  Pages: 67-70
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents.2005
- Author(s)
  Arimoto-Kobayashi S. et al.
- Journal Title
  
  Mutagenesis 20
  
  Pages: 229-233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents.2005
- Author(s)
  Arimoto-Kobayashi, S.他3名
- Journal Title
  
  Mutagenesis 20
  
  Pages: 229-233
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Inhibitory Effects of Heterocyclic Amine - Induced DNA Adduct Formation in MOuse Liver and Lung by beer.2005
- Author(s)
  Arimoto-Kobayashi, S.他5名
- Journal Title
  
  Journal of Agriculture and Food Chemistry 53
  
  Pages: 812-815
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Inhibitory effects of heterocyclic amine - induced DNA adduct formation in mouse liver and lung by beer.2005
- Author(s)
  Arimoto-Kobayashi, S, 他5人
- Journal Title
  
  Journal of Agriculture and Food Chemistry 53
  
  Pages: 812-815
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents2005
- Author(s)
  Arimoto-Kobayashi, S. 他3名
- Journal Title
  
  Mutagenesis 20
  
  Pages: 229-233
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Improved method for preparation of S9-activated heterocyclic amines.2003
- Author(s)
  Arimoto-Kobayashi, S. 他1人
- Journal Title
  
  Environmental Mutagen Research 25
  
  Pages: 77-81
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] Inhibitory effects of (-)-epigallocatechin gallate on the mutation, DNA strand cleavage and DNA-adduct formation by heterocyclic amines2003
- Author(s)
  Arimoto-Kobayashi, S. 他6人
- Journal Title
  
  Journal of Agriculture and Food Chemistry 51
  
  Pages: 5150-5153
- Data Source
  KAKENHI-PROJECT-15510053
[Journal Article] A possible photosensitizer : tobacco-specific nitrosamine, 4-(N-methylnitrosamino)-1-(3-pyridy1)-1-butanone (NNK), induced mutations, DNA strand breaks and oxidative and methylative damage with UVA
- Author(s)
  Arimoto-Kobayashi S. et al.
- Journal Title
  
  Mutation Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510053
[Presentation] 発癌への関与が疑われる口腔常在細菌Fusobacterium nucleatum（ATCC25586）抽出物の変異原性評価2020
- Author(s)
  有元佐賀惠、苔口　進
- Organizer
  第27回日本がん予防学会総会がん予防学術大会2020米子
- Data Source
  KAKENHI-PROJECT-19K10087
[Presentation] N-ニトロソピロリジンのUVA活性化による小核誘発2018
- Author(s)
  妹尾詠美、友實直美、有元佐賀惠
- Organizer
  日本環境変異原学会第47回大会
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] N-ニトロソプロリンのUVA照射により生じる変異原性物質の安定性2018
- Author(s)
  彌久末晶子、友實直美、田中範子、有元佐賀惠
- Organizer
  第40回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] N-ニトロプロリン存在下UVA照射によるM13mp2ファージDNAの変異スペクトルとDNA付加体形成2017
- Author(s)
  有元　佐賀惠、木村　幸子、蓬莱　友美、安東　佳子
- Organizer
  39回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] Mismatch repair systems might facilitate chromosomal recombination induced by NDMA, UV and X-rays in Drosophila2017
- Author(s)
  Tomoe Negishi, Kentaro Taira, Emiko Mori, Keiko Miyamoto, Kenji Yamada, Sakae Arimoto, Yasuhiro Kamei, Kazuo Negishi
- Organizer
  The 12th International Conference and 5th Asian congress on Environmental Mutagens
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] Mutation Spectrum Resulting In M13mp2 Phage DNA Exposed To N-Nitrosoproline With UVA Irradiation2017
- Author(s)
  Sakae Arimoto-Kobayashi, Yumi Horai, Yoshiko Ando, Tomoe Negishi and Sachiko Kimura
- Organizer
  The 12th International Conference and 5th Asian congress on Environmental Mutagens
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] UVA活性化を受けたN-ニトロソプロリンのヒト表皮角化細胞に与える光毒性と細胞内cGMP量の変化2016
- Author(s)
  友實直美、田中範子、根岸友恵、有元佐賀惠
- Organizer
  日本環境変異原学会大45回大会
- Place of Presentation
  つくば国際会議場、つくば
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] UVA irradiated N-nitrosoproline released nitric oxide, and produced photo-genotoxic effects and disturbance of cGMP concentration in human keratinocyte cells2016
- Author(s)
  Naomi Tomozane, Noriko Tanaka, Tomoe Negishi and Sakae Arimoto-Kobayashi
- Organizer
  第９回国際NO学会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] 環境および医薬品混在物の光変異原性-重合開始剤の光変異原性2016
- Author(s)
  有元佐賀惠、市原英則、高井真理子、河崎陽一、北村佳久、千堂年昭
- Organizer
  第３8回日本光医学・光生物学会
- Place of Presentation
  京都リサーチパーク、京都
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] DNA adducts formation with UVA-activated N-nitrosoproline with aerobic and anaerobic conditions2015
- Author(s)
  Sakae Arimoto-Kobayashi, Chiharu Asahi, Shuhei Aoyama, Naomi Tomozane and Tomoe Negishi
- Organizer
  The 7th Asia and Oceania Conference on Photobiology
- Place of Presentation
  Academia Sinica, Taipei, Taiwan
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] タバコ副流煙の変異原性に対する光照射の影響2015
- Author(s)
  市原英則、根岸友恵、有元佐賀惠
- Organizer
  日本環境変異原学会44回大会
- Place of Presentation
  九州大学馬出キャンパス、福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] 嫌気条件でのUVA活性化ニトロソプロリンによるDNA損傷解析2015
- Author(s)
  有元佐賀惠、旭千春、青山章平、横山達也、根岸友恵
- Organizer
  第３７回日本光医学・光生物学会
- Place of Presentation
  宮崎市シーガイアコンベンションセンター、宮崎市
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-15K00556
[Presentation] Release of nitric oxide and formation of mutagenic substance from UVA irradiated N-nitrosoproline in non-aqueous lipids2014
- Author(s)
  Arimoto-Kobayashi,S., Moriwaki, N., Tanaka, N., Okamoto, K. and Negishi, T
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International (SFRRI2014)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] Release of nitric oxide and formation of mutagenic substance from UVA irradiated N-nitrosoproline in non-aqueous lipids2014
- Author(s)
  Sakae Arimoto-Kobayashi, Naofumi Moriwaki, Noriko Tanaka, Keinosuke Okamoto and Tomoe Negishi
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] 変異原性物質とDNA の光化学反応2013
- Author(s)
  有元佐賀惠
- Organizer
  日本環境変異原学会42回大会
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] 日本環境変異原学会シンポジウムII「光遺伝毒性の最近の動向」2013
- Author(s)
  有元佐賀惠
- Organizer
  「変異原性物質とDNA の光化学反応」、日本環境変異原学会42回大会
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] N-ニトロソプロリンのUVA 光反応によるDNA 付加体形成2013
- Author(s)
  旭千春、青山周平、岡本敬の介、根岸友恵、波多野力、有元佐賀惠
- Organizer
  第35回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] UVA活性化N-ニトロソプロリンによるヒトケラチノサイト由来細胞への遺伝毒性2013
- Author(s)
  田中範子、森脇直史、岡本敬の介、根岸友恵、佐藤聡、有元佐賀惠
- Organizer
  第３５回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] N-ニトロソプロリンのUVA光反応によるDNA付加体形成2013
- Author(s)
  旭千春、青山周平、岡本敬の介、根岸友恵、波多野力、有元佐賀惠
- Organizer
  第３５回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] Near ultraviolet light-mediated reaction between N-nitrosoproline and DNA : Isolation and identification of new adducts2013
- Author(s)
  Arimoto-Kobayashi, S., Aoyama, S., Asahi, C., Sano, K., Machida, M., Okamoto, K., Negishi, T., Kimura, S., Suzuki, T. and Hatano, T
- Organizer
  The 6th Asia and Oceania Conference on Photobiology
- Place of Presentation
  シドニー
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] UVA 活性化N-ニトロソプロリンによるヒトケラチノサイト由来細胞への遺伝毒性2013
- Author(s)
  田中範子、森脇直史、岡本敬の介、根岸友恵、佐藤聡、有元佐賀惠
- Organizer
  第35回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] Near ultraviolet light-mediated reaction between N-nitrosoproline and DNA: Isolation and identification of new adducts2013
- Author(s)
  Arimoto-Kobayashi S, Aoyama S, Asahi C, Sano K, Machida M, Okamoto K, Negishi T, Kimura S, Suzuki T and Tsutomu Hatano
- Organizer
  The 6th Asia and Oceania Conference on Photobiology
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] UVA活性化N-ニトロソプロリンによる新規核酸付加体2012
- Author(s)
  有元佐賀惠、青山周平、田中範子、佐野嘉容子、根岸友恵、波多野力、鈴木利典、木村幸子
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] UVA 活性化N-ニトロソプロリンによる新規核酸付加体2012
- Author(s)
  有元佐賀惠、青山周平、田中範子、佐野嘉容子、根岸友恵、波多野力、鈴木利典、木村幸子
- Organizer
  第34回日本光医学・光生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] N-ニトロソプロリンの光活性化による核酸修飾2011
- Author(s)
  青山周平、佐野嘉容子,波多野力、木村幸子、有元佐賀惠
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] N-ニトロソプロリンの光活性化による核酸修飾2011
- Author(s)
  青山周平、佐野嘉容子, 波多野力、木村幸子、有元佐賀惠
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  大阪市
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] ニトロソアミンはUVAを吸収してNOを放出し、2次的にDNAの鎖切断・酸化的傷害・突然変異を誘発する2011
- Author(s)
  有元佐賀惠、根岸友恵、岡本敬の介、薬師径子
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] 培養ヒトケラチノサイトによる化学物質の光細胞毒性・光遺伝毒性試験2011
- Author(s)
  堀ノ内眞弓、有元佐賀惠
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京都
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] 培養ヒトケラチノサイトによる化学物質の光細胞毒性・光遺伝毒性試験2011
- Author(s)
  堀ノ内眞弓、有元佐賀惠
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] Analysis of photoproducts from a UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine or 2'-deoxyguanosine2011
- Author(s)
  Aoyama, S., Sano, K., Hatano, T., Kimura, S. and Arimoto-Kobayashi, S
- Organizer
  The 5th Asia and Oceania Conference on Photobiology
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23510075
[Presentation] N-ニトロソプロリンとデオキシアデノシンとのUVA光反応解析2010
- Author(s)
  青山周平、佐野嘉容子、木村幸子、波多野力、岡本敬の介、根岸友恵、有元佐賀惠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] N-dialkylnitrosaminesはUVAを吸収してNOを放出し、DNAの鎖切断・酸化的傷害を引き起こし、突然変異を誘発する2010
- Author(s)
  有元佐賀惠
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] N-ニトロソプロリンの不飽和脂肪酸中での光活性化2010
- Author(s)
  森脇直史、鈴木利典、有元佐賀惠
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] N-ニトロソプロリンの不飽和脂肪酸中での光活性化2010
- Author(s)
  森脇直史、鈴木利典、有元佐賀惠
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  東京都
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] 変異原物質2-クロロ-4-メチルチオ酪酸によるDNA損傷の解析2010
- Author(s)
  木村幸子, 瀬川絢子, 有元佐賀恵
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県桃太郎アリーナ
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21500785
[Presentation] Analysis of photoproducts from a UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine2010
- Author(s)
  Shuhei Aoyama、Kayoko Sano、Tsutomu Hatano、Sachiko Kimura、Sakae Arimoto-Kobayashi
- Organizer
  第37回国際核酸化学シンポジウム
- Place of Presentation
  横浜市
- Year and Date
  2010-11-10
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] 紫外線照射下でのN-ニトロソプロリンによるグルタチオンのニトロソ化とチロシンのニトロ化2009
- Author(s)
  仲敦史、鈴木利典、有元佐賀惠
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪市
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] N-ニトロソプロリンのUVA光反応におけるNOの産生2009
- Author(s)
  森脇直史、根岸友恵、岡本敬の介、有元佐賀惠
- Organizer
  第48回日本薬学会中国四国支部学術大会
- Place of Presentation
  徳島市
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] UVA光活性化N-ニトロソプロリンによるデオキシグアノシンの反応生成物解析2008
- Author(s)
  佐野嘉容子、町田雅希、根岸友恵、岡本敬の介、鈴木利典、木村幸子、有元佐賀惠
- Organizer
  第47回日本薬学会中国四国支部学術大会
- Place of Presentation
  岡山市
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] N-ニトロソプロリンとデオキシグアノシンとのUVA光反応生成物2008
- Author(s)
  有元佐賀惠、佐野嘉容子、町田雅希
- Organizer
  第67回日本癌学会学術大会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20510064
[Presentation] UVA活性化N-nitrosoprolineと2'-deoxyguanosineとの反応生成物の解析2008
- Author(s)
  有元佐賀惠
- Organizer
  第30回日本光医学会・光生物学会
- Place of Presentation
  松江市
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20510064

1. NEGISHI Tomoe (80116491)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. KIMURA Sachiko (70225035)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. TSUCHIYA Tomofusa (80012673)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KURODA Teruo (80304327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OKAMOTO Keinosuke (70131183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MIO Mitsunobu (70190600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIZUSHIMA Tohru (00264060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MASUDA Kazuhumi (00243486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NOMURA Tomohiko (00289315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMANAKA Hiroyasu (30202386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHINODA Sumio (50029782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kokeguchi Susumu (10144776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 月原冨武 (00032277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 横田憲治 (00243460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 村上純 (40362983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 渡辺朱理 (80585026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TRACEY B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHUKER D.E.G

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FARMER P.B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Arimoto Sakae 有元 佐賀惠

ARIMOTO Sakae 有元 佐賀惠

KOBAYASHI Sakae 小林 佐賀恵

KOBAYASHI-ARIMOTO Sakae 小林 佐賀惠

有元 佐賀惠 アリモト サカエ

有元 佐賀恵 アリモト サカエ

Research Projects

Research Products

Co-Researchers

Survay on carcinogenic risks by oral bacteria and their measures

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of photochemical activation of endogenic and environmental N-nitrosamines and its photogenotoxicity and disturbance on cell functionsPrincipal Investigator

Principal Investigator

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Research Institution

UVA activated N-nitrosoproline induced damages on DNA, protein and membrane, and disturbance of signal transductionPrincipal Investigator

Principal Investigator

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Research Institution

塩蔵食品由来変異原2-クロロ-4-メチルチオ酪酸によるDNA損傷に関する研究

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

DNA and protein modification and disturbance on cell system with NO produced from photo-reactivation of N-nitrosated amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Reaction mechanisms and evaluation of toxicity of the formation of nitric oxide from UVA-irradiated N-nitroso-compoundPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Studies on the secretion and maturation pathway of bacterial exotoxin

Principal Investigator

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Research Institution

Tne initiator of chromosomal DNA replication in E. coli.

Principal Investigator

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GENETIC DAMAGES IN DNA EXPOSED N-NITROSO AMINO ACIDS WITH UVA RADIATIONPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of analytical methods for DNA-carcinogen adductsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Antimutagenic, anti-inflammatory, and antioxidative activities of the juice of Vitis ficifolia var. Ganebu, a woody vine in the grape family, known as Ryukyu-ganebu in Japan2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and identification of photoproducts from UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutation spectrum resulting in M13mp2 phage DNA exposed to N -nitrosoproline with UVA irradiation2017

Arimoto Sakae 有元佐賀惠

ARIMOTO Sakae 有元佐賀惠

KOBAYASHI Sakae 小林佐賀恵

KOBAYASHI-ARIMOTO Sakae 小林佐賀惠

有元佐賀惠アリモトサカエ

有元佐賀恵アリモトサカエ

[Journal Article] Mutagenicity and NO Formation from UVA Irradiated <i>N</i>-Nitrosoproline, and Characterization of Photoproduct Formed in UVA-irradiated Mixture of <i>N</i>-Nitrosoproline with 2′-Deoxyguanosine in Neutral Solution2014