Shiraishi Seiji 白石成二

… Alternative Names

SHIRAISHI Seiji 白石成二

白石成二シライシセイジ

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Researcher Number	90216177
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(医), 上席特任学術研究員
Affiliation (based on the past Project Information) *help	2025: 広島大学, 病院(医), 寄附講座教授 2021 – 2023: 広島大学, 病院(医), 寄附講座教授 2019 – 2020: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, 医師 2016 – 2018: 国立研究開発法人国立国際医療研究センター, その他部局等, 医師 2017: 国立国際医療研究センター, 研究所, 室長 … More 2015: 国立研究開発法人国立がん研究センター, 中央病院, 医員 2011 – 2014: 独立行政法人国立がん研究センター, 研究所, ユニット長 2012: 独立行政法人国立がん研究センター, がん疼痛研究室, 室長 2010 – 2012: 国立がん研究センター研究所, がん疼痛研究室, 室長 1993: 宮崎医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies Except Principal Investigator Functional basic dentistry / Anesthesiology
Keywords	Principal Investigator ミクログリア / 神経障害性疼痛 / miRNA / ナトリウムチャネル / カルシニューリン / Nav1.7 / FK-506 / 免疫抑制薬 / アロディニア / 間葉系幹細胞 … More / 幹細胞 / シュワン細胞 / 脂肪由来幹細胞 / エストロゲン / 疼痛 / アロマターゼ / ovariectomy / aromatase / GPR30 / がん性疼痛 / モルヒネ / 癌 / tail flick test / ケタミン / NMDA … More Except Principal Investigator がん性疼痛 / イオントラッピング / 細胞内pH / ミトコンドリア電位 / 脱共役作用 / プロトントラッピング / プロポフォール / プロトノフォア / pH勾配 / アポトーシス / ミトコンドリア / プロポフオール / 抗癌作用 / 麻酔薬 / がん細胞培養上清 / 新規内因性鎮痛関連物質 / 神経障害性疼痛 / 疼痛 / 歯科薬理学 / グリシントランスポーター阻害薬 / 下降性痛覚抑制系 / グリシン受容体 / PAF受容体拮抗薬 / 血小板性化因子(PAF) / グリシントランスポ一ター阻害薬 / グリシントランスポーター / 副作用軽減 / モルヒネ作用増強 / がん生存率 / PAF阻害薬 / 下降性疼痛抑制系 / モルヒネ / PAF 阻害薬 / 血小板活性化因子(PAF) / アロディニア / 癌性疼痛 Less

Alarminに着目した腰部脊柱管狭窄症の病態理解に基づく新規鎮痛薬の開発Principal Investigator
- Principal Investigator
  
  白石成二
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hiroshima University
移植患者の免疫抑制薬による疼痛の発症メカニズムを明らかにしその治療法を確立するPrincipal Investigator
- Principal Investigator
  
  白石成二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hiroshima University
Evidence-based strategies to treat neuropathic pain with stem cell transplantationsPrincipal Investigator
- Principal Investigator
  
  Shiraishi Seiji
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hiroshima University
  Department of Clinical Research, National Hospital Organization Kure Medical Center
  National Center for Global Health and Medicine
Search of optimal anesthetic in cancer patients was evaluated from apoptosis induced cancer cells
- Principal Investigator
  
  Onizuka Shin
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kyushu University of Health and Welfare
The search for novel analgesics based on pain control with aromatase and GPR30Principal Investigator
- Principal Investigator
  
  Shiraishi Seiji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  National Center for Global Health and Medicine
  National Cancer Center Japan
Role of miRNA for the opioid tolerance in cancer pain treatmentPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Seiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  National Center of Neurology and Psychiatry
Development of mechanism-based novel medicaments to pain in advanced cancer
- Principal Investigator
  
  MORITA Katsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Identification of tumor-cell producing novel endogenous analgesic substance
- Principal Investigator
  
  MORITA Katsuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
脊髄くも膜下投与によるケタミンの鎮痛機序に関する研究Principal Investigator
- Principal Investigator
  
  白石成二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  宮崎医科大学

All 2022 2021 2013 2011 2010

All Journal Article Presentation Patent

[Journal Article] Intravenous administration of human mesenchymal stem cells derived from adipose tissue and umbilical cord improves neuropathic pain via suppression of neuronal damage and anti-inflammatory actions2022
- Author(s)
  3.Miyano K, Ikehata M, Ohshima K, Yoshida Y, Nose Y, Yoshihara S, Oki K, Shiraishi S, Uzu M, Nonaka M, Higami Y, Narita M, Uezono Y.
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 2 Pages: e0262892-e0262892
- DOI
  10.1371/journal.pone.0262892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-20K07750, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-18K08842
[Journal Article] Pain-releasing action of Platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action2013
- Author(s)
  Motoyama N, Morita K, Kitayama T, Shiraishi S, Uezono Y, Nishimura F, Kanematsu T, Dohi T
- Journal Title
  
  Eur J Pain
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390349
[Journal Article] Pain-releasing action of Platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action2013
- Author(s)
  Motoyama N, Morita K, Kitayama T, Shiraishi S, Uezono Y, Nishimura F, Kanematsu T, Dohi T.
- Journal Title
  
  European Journal of Pain
  
  Volume: (Epub ahead of print)(in press) Issue: 8 Pages: 1156-1167
- DOI
  10.1002/j.1532-2149.2013.00289.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390349, KAKENHI-PROJECT-22590510, KAKENHI-PROJECT-24590740
[Patent] 癌性疼痛を処理するための組成物およびその利用2011
- Inventor(s)
  森田克也,土肥敏博,本山直世,北山友也,兼松隆,白石成二
- Industrial Property Rights Holder
  国立大学法人広島大学,独立行政法人国立がん研究センター
- Industrial Property Rights Type
  特許
- Filing Date
  2011-12-09
- Overseas
- Data Source
  KAKENHI-PROJECT-22390349
[Patent] 癌性痛痛を処理するための組成物およびその利用2011
- Inventor(s)
  森田克也, 土肥敏博, 本山直世, 北山友也, 兼松隆, 白石成二
- Industrial Property Rights Holder
  国立大学法人広島大学 ; 独立行政法人国立がん研究センター
- Filing Date
  2011-12-09
- Overseas
- Data Source
  KAKENHI-PROJECT-22390349
[Patent] 疼痛を処理するための組成物およびその利用2010
- Inventor(s)
  森田克也,土肥敏博,本山直世,北山友也,兼松隆,白石成二
- Industrial Property Rights Holder
  国立大学法人広島大学,独立行政法人国立がん研究センター
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2010-274581
- Filing Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22390349
[Patent] 痛痛を処理するための組成物およびその利用2010
- Inventor(s)
  森田克也, 土肥敏博, 本山直世, 北山友也, 兼松隆, 白石成二
- Industrial Property Rights Holder
  国立大学法人広島大学 ; 独立行政法人国立がん研究センター
- Industrial Property Rights Type
  特許
- Filing Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22390349
[Presentation] 脂肪および臍帯由来間葉系幹細胞は炎症および脱髄を改善し神経障害性疼痛を緩和させる2021
- Author(s)
  宮野加奈子、池畑農、大島佳織、吉田有輝、能勢泰寛、吉原誠一、隠岐勝幸、白石成二、宇津美秋、野中美希、樋上賀一、成田年、上園保仁
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K08842

1. MORITA Katsuya (10116684)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. MOTOYAMA Naoyo (70509661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KANEMATSU Takashi (10264053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KITAYAMA Shigeo (80177873)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. DOHI Toshihiro (00034182)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. UEZONO Yasuhito (20213340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. KITAYAMA Tomoya (60363082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Onizuka Shin (20264393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丸田豊明 (20363591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 野中美希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiraishi Seiji 白石 成二

SHIRAISHI Seiji 白石 成二

白石 成二 シライシ セイジ

Research Projects

Research Products

Co-Researchers

Alarminに着目した腰部脊柱管狭窄症の病態理解に基づく新規鎮痛薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

移植患者の免疫抑制薬による疼痛の発症メカニズムを明らかにしその治療法を確立するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evidence-based strategies to treat neuropathic pain with stem cell transplantationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search of optimal anesthetic in cancer patients was evaluated from apoptosis induced cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The search for novel analgesics based on pain control with aromatase and GPR30Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of miRNA for the opioid tolerance in cancer pain treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of mechanism-based novel medicaments to pain in advanced cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of tumor-cell producing novel endogenous analgesic substance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脊髄くも膜下投与によるケタミンの鎮痛機序に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intravenous administration of human mesenchymal stem cells derived from adipose tissue and umbilical cord improves neuropathic pain via suppression of neuronal damage and anti-inflammatory actions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pain-releasing action of Platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action2013

Author(s)

Journal Title

Data Source

[Journal Article] Pain-releasing action of Platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action2013

Author(s)

Journal Title

DOI

Data Source

[Patent] 癌性疼痛を処理するための組成物およびその利用2011

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

Shiraishi Seiji 白石成二

SHIRAISHI Seiji 白石成二

白石成二シライシセイジ