Nakano Naoko 中野直子

… Alternative Names

NAKANO Naoko 中野直子

中野直子ナカノナオコ

Less

Researcher Number	90222166
Other IDs
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 客員准教授
Affiliation (based on the past Project Information) *help	2024: 東京理科大学, 研究推進機構生命医科学研究所, 客員准教授 2022: 東京理科大学, 研究推進機構生命医科学研究所, 客員准教授 2017 – 2021: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2000 – 2006: 東京理科大学, 生命科学研究所, 助教授 1997 – 1998: 東京理科大学, 生命科学研究所, 助教授
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Immunology / Immunology / Biological Sciences Except Principal Investigator Radiation science / Biological Sciences
Keywords	Principal Investigator 表皮自己抗原 / 自己抗体 / 樹状細胞 / 自己免疫病 / Foxp3 / トレランス / T細胞 / CD4 T細胞 / モデルマウス / 天疱瘡 … More / 自己抗原特異的リンパ球 / 皮膚 / 表皮抗原 / Tfh細胞 / アナジー化CD4T細胞 / 表皮細胞ストレス / HVEM / cDC1 / B細胞クラススイッチ / Tfh / CD4T細胞のアナジー化 / commitment / regulatory T cells / 分化決定 / レギュラトリーT細胞 / TGF-β1 / T cell / immune regulation / トランスフォーミンググロースファクターβ1 / TGF-betal / TGF-beta1 / 免疫調節 / 実験モデル / 発癌 / トランスジェニックマウス / ペプチド抗原 … More Except Principal Investigator 免疫学 / Foxp3 / 制御性T細胞 / 内用放射線治療 / がん免疫 / 癌 / 放射線 / Treg抗体 / Treg細胞 / Treg / 核医学治療 / Immunological self-tolerance / Genetic susceptibilit / Co-stimulatory molecule / Semaphoring / Dendritic cells / Regulatory T cell / Autoimmune disease / CTLA-4 / GITR / 病理学 / 単クローン抗体 / CD25 / helios / Gpr83 / GITR-L / 移植免疫 / 腫瘍免疫 / 自己免疫 / 樹状細胞 / 遺伝的疾患感受性 / セマフォリン / 教刺激分子 / 免疫自己寛容 / 自己免疫病 / ヒト免疫細胞 / エイズ / SCIDマウス Less

樹状細胞ーT細胞間相互作用を基軸とした組織特異的自己抗体産生機構の解明Principal Investigator
- Principal Investigator
  
  中野直子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tokyo University of Science
Molecular mechanisms of DC activation in autoantibody-producing Pemphigus-like model micePrincipal Investigator
- Principal Investigator
  
  Nakano Naoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tokyo University of Science
Development of radiotheranostics agent using Fab fragment of anti-regulatory T cells
- Principal Investigator
  
  Uehara Tomoya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
細胞の癌化に伴う免疫監視機構の発動とその抑制Principal Investigator
- Principal Investigator
  
  中野直子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Factors that regulate the expression of Foxp3 to determine the commitment of regulatory T cellPrincipal Investigator
- Principal Investigator
  
  NAKANO Naoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Immune tolerance and regulation towards understanding and cure of autoimmune disease
- Principal Investigator
  
  SAKAGUCHI Shimon
- Project Period (FY)
  2001 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Commitment of T cell differentiation and immuune regulationPrincipal Investigator
- Principal Investigator
  
  NAKANO Naoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
特異的ペプチドによるトレランスの確立と破綻Principal Investigator
- Principal Investigator
  
  中野直子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo University of Science
HIV感染の新しい動物モデルの確立
- Principal Investigator
  
  穂積信道
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science

All 2023 2021 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Lack of Herpes VIrus Entry Mediator Signals in thymocytes impairs conventional CD8 T cell selection and promotes memory-like CD8 T cell development2023
- Author(s)
  Yuki Kugii, Yui Kuroki, Yasushi Hara, Ryo Goitsuka and Naoko Nakano
- Journal Title
  
  The Journal of Immunology
  
  Volume: 210 Issue: 10 Pages: 1-12
- DOI
  10.4049/jimmunol.2200748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08681, KAKENHI-PROJECT-21H02372
[Journal Article] NFAT-mediated expression of TGF-β1 in tolerant T cells2007
- Author(s)
  Nakano N., Hosokawa H., Kohyama M., Hozumi N
- Journal Title
  
  J. Immunol 178
  
  Pages: 3067-3075
- Data Source
  KAKENHI-PROJECT-17047038
[Journal Article] The existence of CD11c^+ sentinel and F4/80^+ interstitial dendritic cells in dental pulp and their dynamics and functional properties.2006
- Author(s)
  Zhang, J, Kawashima N, Suda H, Nakano Y, Takano Y, Azuma M.
- Journal Title
  
  Int Immunol. 18
  
  Pages: 1375-1384
- NAID
  10018773673
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Ca^+ signaling downregulate TGF-β1 gene expression in CD4^+ T cells.2005
- Author(s)
  Kohyama M., Yasogi Y., Nakano N., Ise Y., Inouye S., Kaminogawa S., Hozumi N
- Journal Title
  
  Biochem. Biophys. Res. Commun. 323
  
  Pages: 494-499
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590413
[Journal Article] Ca^+ signaling downregulate TGF-β1 gene expression in CD4^+ T cells.2005
- Author(s)
  Kohyama M., Yasogi Y., Nakano N., Ise Y., lnouye S., Kaminogawa S., Hozumi N
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 494-499
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590413
[Journal Article] Expression of B7-H1 and B7-DC on the airway epithelium is enhanced by double-stranded RNA.2005
- Author(s)
  Tsuda M, Matsumoto K, Inoue H, Matsumura M, Nakano T, Mori A, Azuma M, Nakanishi Y.
- Journal Title
  
  Biochem Biophys Res Commun 330
  
  Pages: 263-270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] 制御性T細胞による免疫抑制2005
- Author(s)
  中野直子
- Journal Title
  
  臨床免疫学(上) 63増刊
  
  Pages: 414-419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590413
[Journal Article] The regulation of immune responses by regulatory T cells2005
- Author(s)
  Naoko Nakano
- Journal Title
  
  Rinshomennekigaku suppl.63
  
  Pages: 414-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590413
[Journal Article] B7-DC regulates asthumatic responses by interferon-g-dependent mechanism.2004
- Author(s)
  Matsumoto K, Inoue H, Nakano T, Tsuda M, Yoshiura Y, Fukuyama S, Tsushima F, Hoshino T, Aizawa H, Akiba h, Pardoll D, Yagita H, Azuma M, Hara N.
- Journal Title
  
  J. Immunol 172
  
  Pages: 2530-2541
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Presentation] Regulation of epidermal antigen-specific antibody production by autoreactive T cells2021
- Author(s)
  Haruki Okuda, Naoko Nakano
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-20K08681

1. 後飯塚僚 (50301552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. SAKAGUCHI Shimon (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. INABA Kayo (00115792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KIKUTANI Hitoshi (80161412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. AZUYMA Miyuki (90255654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. HIROSE Sachiko (00127127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Uehara Tomoya (10323403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 穂積信道 (60051744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉村泰典 (10129736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 今田美恵 (50291703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高橋武司 (80335215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 藤井博史 (80218982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakano Naoko 中野 直子

NAKANO Naoko 中野 直子

中野 直子 ナカノ ナオコ

Research Projects

Research Products

Co-Researchers

樹状細胞ーT細胞間相互作用を基軸とした組織特異的自己抗体産生機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of DC activation in autoantibody-producing Pemphigus-like model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of radiotheranostics agent using Fab fragment of anti-regulatory T cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞の癌化に伴う免疫監視機構の発動とその抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Factors that regulate the expression of Foxp3 to determine the commitment of regulatory T cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immune tolerance and regulation towards understanding and cure of autoimmune disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Commitment of T cell differentiation and immuune regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

特異的ペプチドによるトレランスの確立と破綻Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

HIV感染の新しい動物モデルの確立

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Lack of Herpes VIrus Entry Mediator Signals in thymocytes impairs conventional CD8 T cell selection and promotes memory-like CD8 T cell development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NFAT-mediated expression of TGF-β1 in tolerant T cells2007

Author(s)

Journal Title

Data Source

[Journal Article] The existence of CD11c^+ sentinel and F4/80^+ interstitial dendritic cells in dental pulp and their dynamics and functional properties.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Ca^+ signaling downregulate TGF-β1 gene expression in CD4^+ T cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Ca^+ signaling downregulate TGF-β1 gene expression in CD4^+ T cells.2005

Author(s)

Nakano Naoko 中野直子

NAKANO Naoko 中野直子

中野直子ナカノナオコ