MIKAMI Tetuo 三上哲夫

… Alternative Names

三上哲夫ミカミテツオ

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Researcher Number	90286352
Other IDs
Affiliation (Current)	2025: 東邦大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 東邦大学, 医学部, 教授 2013 – 2014: 東邦大学, 医学部, 教授 2012: 北里大学, 医学部, 准教授 2010: 北里大学, 医学部, 准教授 2007 – 2008: Kitasato University, 医学部, 准教授 … More 2006: Kitasato University, Pathology, Associate Professor, 医学部, 助教授 2004 – 2005: 北里大学, 医学部, 講師 1999 – 2001: 北里大学, 医学部, 講師 1998: 北里大学, 医学部・病理学, 助手 1997 – 1998: 北里大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Human pathology / Human pathology Except Principal Investigator Basic Section 49020:Human pathology-related / Human pathology / Human pathology
Keywords	Principal Investigator 潰瘍性大腸炎 / 大腸癌 / 潰瘍性大腸炎関連腫瘍 / 癌 / 大腸がん / 細胞接着因子 / sialyl LewisX / laminin5γ2 / β-catenin / methylation secific PCR … More / methylguanine DNA methyltransferase / DNAメチル化 / p16 / E-cadherin / hMLH1 / MGMT / survivin / Bcl-2 / Ki-67 / survivin(サバイビン) / アポトーシス / 異形成 … More Except Principal Investigator 大腸癌 / Hes1 / hASH1 / thyroiditis / 甲状腺癌 / 甲状腺炎 / 発がん / 患者腫瘍組織移植モデル / エストロゲン濃度 / 右側癌 / 閉経後女性 / ミスマッチ修復タンパク質 / ESR2 CA repeat多型 / エストロゲン受容体β / 右側 / 高齢者 / エストロゲン / 結腸癌 / 静脈侵襲 / 腫瘍浸潤 / 血行性転移 / Neuroendocrine carcinoma / Gastric cancer / 病理学 / 神経内分泌癌 / 胃癌 / carcinogenesis / Ras gene / RET protoncogene / thyroid cancer / Ras遺伝子 / RETがん遺伝子 / apoptosis / cell proliferation / differentiation / telemere length / telemerase / thyroid tumors / テロメレーズ / アポトーシス / 細胞増殖 / 細胞分化 / テロメア / テロメラーゼ / 細胞間相互作用 / 慢性臓器炎 / プロテオミックス / ゲノミックス / 発癌 / retinoic acid / aoptosis / GRIM-19 / NF-kB / myofibroblast / petoxiredoxin-1 / olfactomedin-4 / 粘膜リモデリング / 潰瘍性大腸炎 / 上皮細胞 / 間質細胞 / 慢性炎症 Less

大腸癌に対するエストロゲン作用の多様性についての包括的研究
- Principal Investigator
  
  本間尚子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Toho University
A pathological study to establish new criteria for venous invasion in colorectal cancer
- Principal Investigator
  
  FUKASAWA Yuri
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Toho University
Factors related with carcinogenesis and invasion of ulcerative colitis-associated cancerPrincipal Investigator
- Principal Investigator
  
  MIKAMI Tetuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Toho University
  Kitasato University
Insufficient crosstalk between epithelium and stroma in chronic inflammation-carcinoma sequence: Analysis of a disease model
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Expression of cell adhesion molecule in ulcerative colitis- associated carcinomaPrincipal Investigator
- Principal Investigator
  
  MIKAMI Tetuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Clinicopathological features of gastric neuroendocrine carcinomas and the roles of hASH1/HES1 in neuroendocrine differentiation of gastric cancers
- Principal Investigator
  
  JIANG Shi-xu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
潰瘍性大腸炎からの発癌におけるメチル化によるDNA修復遺伝子発現低下と遺伝子異常Principal Investigator
- Principal Investigator
  
  三上哲夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
潰瘍性大腸炎関連腫瘍の発生と進展におけるアポトーシス抑制蛋白サバイビンの役割Principal Investigator
- Principal Investigator
  
  三上哲夫
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Promotion effect of lymchocytic thyroiditis in thyroid carcinogenesis by activation of RET protoncogene
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KITASATO UNIVERSITY
The role of telomerase activity in thyroid tumorigenesis
- Principal Investigator
  
  OKAYASU Isao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KITASATO UNIVERSITY

All 2023 2022 2021 2014 2013 2011 2010 2009 2008 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Estrogen Receptor-β Gene Cytosine-Adenine (ESR2-CA) Repeat Polymorphism in Postmenopausal Colon Cancer2023
- Author(s)
  Honma Naoko、Arai Tomio、Matsuda Yoko、Fukunaga Yosuke、Muramatsu Masaaki、Ikeda Shinobu、Akishima-Fukasawa Yuri、Yamamoto Noriko、Kawachi Hiroshi、Ishikawa Yuichi、Takeuchi Kengo、Mikami Tetuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 5 Pages: 4502-4502
- DOI
  10.3390/ijms24054502
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06932, KAKENHI-PROJECT-19H03446
[Journal Article] Estrogen concentration and estrogen receptor-β expression in postmenopausal colon cancer considering patient/tumor background2022
- Author(s)
  Naoko Honma, Tomio Arai, Yoko Matsuda, Yosuke Fukunaga, Yuri Akishima-Fukasawa, Noriko Yamamoto, Hiroshi Kawachi, Yuichi Ishikawa, Kengo Takeuchi, Tetuo Mikami
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 148 Issue: 5 Pages: 1063-1071
- DOI
  10.1007/s00432-021-03889-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06932, KAKENHI-PROJECT-19H03446
[Journal Article] Carcinogenesis of Triple-Negative Breast Cancer and Sex Steroid Hormones2021
- Author(s)
  Naoko Honma, Yoko Matsuda, Tetuo Mikami
- Journal Title
  
  Cancers (Basel)
  
  Volume: 13 Issue: 11 Pages: 2588-2588
- DOI
  10.3390/cancers13112588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06932
[Journal Article] Tumor budding, myofibroblast proliferation, and fibrosis in obstructing colon carcinoma: the roles of Hsp47 and basic fibroblast growth factor2013
- Author(s)
  Xu CJ, Mikami T, Nakamura T, Tsuruta T, Nakada N, Yanagisawa N, Jiang SX, Okayasu I
- Journal Title
  
  Pathology Research and Practice
  
  Volume: 209 Issue: 2 Pages: 69-74
- DOI
  10.1016/j.prp.2012.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590426, KAKENHI-PROJECT-24590427
[Journal Article] Submucosal fibrosis and basic-fibroblast growth factor-positive neutrophils correlate with colonic stenosis in cases of ulcerative colitis.2011
- Author(s)
  Yamagata M, Mikami T, 他、Okayasu I
- Journal Title
  
  Digestion 84
  
  Pages: 12-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Cytoglobin expression of rectal subepithelial myofibroblasts: significant alterations of cytoglobin+ stromal cells in long-standing ulcerative colitis.2011
- Author(s)
  Okayasu I, Mikami T, Yoshida T, 他
- Journal Title
  
  Histol Histopathol 26
  
  Pages: 679-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] CITED2 is activated ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid.2010
- Author(s)
  Yoshida T, Sekine T, Aisaki K, Mikami T, Kanno J, Okayasu I.
- Journal Title
  
  J Gastroenterol 46
  
  Pages: 339-349
- NAID
  10029027845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Mucosal remodeling in long-standing ulcerative colitis with colorectal neoplasia: significant alterations of NCAM+or αSMA+ subepithelial myofibroblasts and interstitial cells.2009
- Author(s)
  Okayasu I, Yoshida T, Mikami T, Hana K, Yokozawa T, Araki K, Mitsuhashi J, Kikuchi M, Adachi E, Sada M.
- Journal Title
  
  Pathol Int 59
  
  Pages: 701-711
- NAID
  10027381791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590353
[Journal Article] Tumor budding is predictive of lymphatic involvement and lymph node metastasis in submucosal invasive colorectal adenocarcinomas and in non polypoid compared with polypoid growth2009
- Author(s)
  Ogawa T, Yoshida T, Tsuruta T, Tokuyama W, Adachi S, Kikuchi M, Mikami T, Saigenji K, Okayasu I
- Journal Title
  
  Scandinavian Journal of Gastroenterology 44
  
  Pages: 605-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590364
[Journal Article] Gastric large cell neuroendocrine carcinomas : a distinct clinicopathological entity.2006
- Author(s)
  Jiang SX, Mikami T, Umezawa A, Saegusa M, Kameya T, Okayasu I
- Journal Title
  
  American Journal of Surgical Pathology 30-8
  
  Pages: 945-953
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590316
[Journal Article] Bottom up cell proliferation with cyclin A and p27^<Kip1> expression in ulcerative colitis-associated dysplasia.2006
- Author(s)
  Mikami T, Yoshida T, et al.
- Journal Title
  
  Pathology International 56(1)
  
  Pages: 10-16
- NAID
  10017320958
- Data Source
  KAKENHI-PROJECT-16790213
[Journal Article] Significant correlation of morphological remodeling in ulcerative colitis with disease duration and between elevated p53 and p21^<WAF1> expression in rectal mucosa and neoplastic development2005
- Author(s)
  Mitsuhashi J, Mikami T et al.
- Journal Title
  
  Pathology International 55(3)
  
  Pages: 113-121
- NAID
  10016474705
- Data Source
  KAKENHI-PROJECT-16790213
[Journal Article] Upregulation of p16(INK4A) and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours2004
- Author(s)
  Yoshida T, Matsumoto N, Mikami T. et al.
- Journal Title
  
  British Journal of Cancer 91(6)
  
  Pages: 1081-1088
- Data Source
  KAKENHI-PROJECT-16790213
[Journal Article] Hign microvascular density is correlated with high VEGF, iNOS, and COX-2 expression in penetrating growth-type gastric carcinomas2004
- Author(s)
  Ichinoe M, Mikami T, et al.
- Journal Title
  
  Histopathology 45(6)
  
  Pages: 621-628
- Data Source
  KAKENHI-PROJECT-16790213
[Presentation] 閉経後トリプルネガティブ乳癌におけるBcl-2およびP53の臨床病理学的意義と年齢の影響についての検討.2023
- Author(s)
  伊藤慶, 本間尚子, 緒方秀昭, 佐々木英一, 山田顕光, 宮下美香, 紺谷桂一, 松田陽子, 新井冨生, 三上哲夫, 澤木正孝
- Organizer
  閉経後トリプルネガティブ乳癌におけるBcl-2およびP53の臨床病理学的意義と年齢の影響についての検討.
- Data Source
  KAKENHI-PROJECT-21K06932
[Presentation] 高齢者triple-negative乳癌におけるPD-L1発現の臨床病理学的意義の検討2022
- Author(s)
  本間尚子、緒方秀昭、山田顕光、松田陽子、紺谷桂一、宮下美香、新井冨生、佐々木英一、澁谷和俊、三上哲夫、澤木正孝
- Organizer
  第30回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06932
[Presentation] 閉経後triple-negative乳癌におけるBcl-2の臨床病理学的意義と年齢との関係性についての検討2022
- Author(s)
  本間尚子、伊藤慶、松田陽子、佐々木英一、深澤由里、赤坂喜清、新井冨生、澁谷和俊、三上哲夫
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K06932
[Presentation] 潰瘍性大腸炎粘膜および潰瘍性大腸炎関連癌におけるcarbonic anhydrase 2の発現の検討2014
- Author(s)
  仲田典広、三上哲夫、一戸昌明、柳澤信之、岡安勲、村雲芳樹
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県　横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24590426
[Presentation] Significant decrease of mucosal cytoglobin+ pericryptal myofibroblasts in long-standing ulcerative colitis with colorectal neoplasia, correlatively with α-SMA and HSP47 phenotype expression.2009
- Author(s)
  Okayasu I, Yoshida M, Mikami T, Hana K, Yokozawa M, Sada M, Fujiwara M, Kawada N
- Organizer
  2009 Advances in Inflammatory Bowel Diseases
- Place of Presentation
  Hollywood, USA
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20590353
[Presentation] 潰瘍性大腸炎関連癌の浸潤とβ-catenin, MMP-7の発現 : sporadic型大腸癌との比較2008
- Author(s)
  三上哲夫、沼田賀子、菊地正臣、荒木香代、吉田功、一戸昌明、柳沢信之、徳山宣、岡安勲
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590364
[Presentation] 潰瘍性大腸炎関連腫瘍では早期からCD44の発現が低下している
- Author(s)
  三上哲夫、林宏行、沼田賀子、蒋世旭、仲田典広、一戸昌明、岡安勲、村雲芳樹
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-24590426
[Presentation] 潰瘍性大腸炎粘膜および潰瘍性大腸炎関連癌におけるCarbonic anhydrase 2発現の検討
- Author(s)
  仲田典広、三上哲夫、一戸昌明、柳澤信之、岡安勲、村雲芳樹
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Data Source
  KAKENHI-PROJECT-24590426
[Presentation] 潰瘍性大腸炎関連腫瘍では早期からCD44の発現が低下している
- Author(s)
  三上哲夫、林宏行、沼田賀子、仲田典広、一戸昌明、岡安勲、村雲芳樹
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590426

1. OKAYASU Isao (20014342)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. SAEGUSA Makoto (00265711)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. FUKASAWA Yuri (90392331)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. YOSHIDA Tsutomu (90316943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. SATO Yuichi (30178793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. JIANG Shi-xu (70276153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 藤澤千恵 (10393000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 本間尚子 (70321875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 林孝典 (40724315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 下野洋平 (90594630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIKAMI Tetuo 三上 哲夫

三上 哲夫 ミカミ テツオ

Research Projects

Research Products

Co-Researchers

大腸癌に対するエストロゲン作用の多様性についての包括的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A pathological study to establish new criteria for venous invasion in colorectal cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Factors related with carcinogenesis and invasion of ulcerative colitis-associated cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Insufficient crosstalk between epithelium and stroma in chronic inflammation-carcinoma sequence: Analysis of a disease model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of cell adhesion molecule in ulcerative colitis- associated carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinicopathological features of gastric neuroendocrine carcinomas and the roles of hASH1/HES1 in neuroendocrine differentiation of gastric cancers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

潰瘍性大腸炎からの発癌におけるメチル化によるDNA修復遺伝子発現低下と遺伝子異常Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

潰瘍性大腸炎関連腫瘍の発生と進展におけるアポトーシス抑制蛋白サバイビンの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Promotion effect of lymchocytic thyroiditis in thyroid carcinogenesis by activation of RET protoncogene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of telomerase activity in thyroid tumorigenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Estrogen Receptor-β Gene Cytosine-Adenine (ESR2-CA) Repeat Polymorphism in Postmenopausal Colon Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estrogen concentration and estrogen receptor-β expression in postmenopausal colon cancer considering patient/tumor background2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Carcinogenesis of Triple-Negative Breast Cancer and Sex Steroid Hormones2021

Author(s)

Journal Title

DOI

Data Source

MIKAMI Tetuo 三上哲夫

三上哲夫ミカミテツオ

[Presentation] 高齢者triple-negative乳癌におけるPD-L1発現の臨床病理学的意義の検討2022