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MORISAKI Takashi  森崎 隆

ORCIDConnect your ORCID iD *help
Researcher Number 90291517
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2015 – 2023: 九州大学, 医学研究院, 共同研究員
2012 – 2014: 九州大学, 医学(系)研究科(研究院), 共同研究員
2009 – 2011: Kyushu University, 大学院・医学研究院, 共同研究員
2007: Kyushu University, Faculty of Medical Sciences, Contracted Research Associate
2006: Kyushu University, Faculty of Medical Sciences, Contracted Research Associate, 大学院医学研究院, 非常勤講師 … More
2005: 九州大学, 大学院・医学研究院, 非常勤講師
2000 – 2003: Kyushu University, Assistant professor, 大学院・医学研究院, 助手
2002: 九州大学, 医学部医学研究院, 助手
2001: 九州大学, 医学部・附属病院, 助手
2001: Kyushu Univ., Graduate school of Medical Science, Assistant Professor, 大学院・医学医学研究所, 助手
1999: 九州大学, 大学院・医学系研究科, 助手
1997 – 1998: 九州大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55040:Respiratory surgery-related / Digestive surgery
Except Principal Investigator
General surgery / Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery / Basic Section 55020:Digestive surgery-related / 内科学一般 / Digestive surgery
Keywords
Principal Investigator
樹状細胞 / 活性化リンパ球 / 免疫療法 / リンパ球 / 抗腫瘍効果 / 増殖能 / MODS / 治療効果予測 / バイオマーカー / 細胞障害活性 … More / 運動能 / 大腸癌 / VEGF / 三次元培養 / 細胞傷害性リンパ球 / 癌組織浸潤リンパ球 / 遊走能 / 捕捉能 / グランザイムB / IFN-gamma / CD86 / CD80 / 細胞傷害性Tリンパ球 / 免疫チェックポイント / CD4T細胞 / 癌免疫治療 / CD8T細胞 / チロシンキナーゼ脱リン酸化酵素 / 新規がん免疫治療開発 / 抗原提示能 / リンパ球活性化 / 免疫チェックポイント分子 / PTPN3 / 小細胞肺癌 / MAML3 / 悪性形質誘導 / SCLC / 腫瘍形成能 / 浸潤能 / 新規治療法開発 / 肺NET / Notchシグナル / Hedgehogシグナル / RBPJ / 免疫細胞療法 / ランダムマイグレーション / 癌免疫療法 / 癌浸潤リンパ球 / リンパ球増殖能 / 細胞傷害活性 / リンパ球運動能 / Molecule transplantation / Cancer therapy / Standard / Vaccine / Exosomes / Dendritic cells / 分子移植 / 癌治療 / 標準化 / ワクチン / エキソゾーム / gene transfection / biliary cancer / microgravity / 3-D culture / bile duct / artificial biliary duct / 浸潤 / 胆管癌 / 胆管上皮 / 人工胆管 / 胆管 / 遺伝子導入 / 胆道癌 / 低重力培養 / 人工胆菅 / 胆菅 / regeneration / bFGF / liver injury / angiogenic factor / endothelial cell / アポトーシス / ミトコンドリア / 血管内皮 / ミトコンドリア障害 / 三次元モデル / Tube formation / 新生血管 / 血管増殖因子 / 血管内皮細胞 / 血管内皮障害 / 多臓器障害 / colon cancer / tumor vaccine / dendritic cells / 癌特異的免疫療法 / 腫瘍ワクチン / 樹状突起細胞 / ベッドサイド / 抗腫瘍活性 / 定量的評価 / リアルタイム評価システム / がん / 患者予後 / 治療効果 / 癌細胞障害活性 / FTYP / random migration / 免疫制御 / 増殖 / 予後予測因子 / 胸腺 / リンパ節 / 大腸癌組織 / アバスチン / FOXP3 / Treg細胞 / 予後因子 / 遊走 / 腫瘍内集積 / VEGFR2 / 制御性T細胞 / Type I collagen / IFN-γ / 固相化 / 低速環流ポンプ … More
Except Principal Investigator
膵癌 / 樹状細胞 / 腫瘍免疫 / IFN-γ / 制御性T細胞 / FR167653 / 免疫療法 / 癌性腹膜炎 / 人工癌組織 / 抗腫瘍効果 / 活性化リンパ球 / ネオアンチゲン / 乳癌 / Functional molecules / Vaccine therapy / Exosomes / 機能分子 / ワクチン療法 / エキソゾーム / TGF-β / Dendritic cells / OX40 / gastric cancer / 胃癌 / 遺伝子導入 / cytokine / ischemia-reperfusion / 腎移植 / 膵移植 / サイトカイン / immunotherapy / artificial carcinoma tissue / artificial connective tissue / 移植 / 人工血管 / 人工リンパ節 / 人工結合織 / 人工腹膜 / 転移 / 浸潤 / NK4 / HGF / アポトーシス / 三次元培養 / 癌免疫療法 / 低重力培養 / 抗腫瘍免疫 / 免疫抑制性微小環境 / Autophagy / 抗原提示能 / 抗原性 / オートファジー / 抗原特異性 / CD8リンパ球 / リンパ球組織浸潤 / 癌免疫治療 / ネオ抗原 / エクソソーム / キメラ抗原受容体T細胞 / 腫瘍免疫微小環境 / CAR-T療法 / CAR-T / 免疫微小環境 / CAF / CAR-T細胞療法 / 抑制性腫瘍免疫微小環境 / 癌関連線維芽細胞(CAF) / 腫瘍浸潤リンパ球(TIL) / MHCテトラマー解析 / 細胞医薬 / TIL / ペプチド / 体細胞性遺伝子変異 / 免疫チェックポイント分子 / 免疫治療効果増強 / 新規免疫治療 / 免疫治療j効果増強 / 新規癌免疫治療 / 免疫チェックポイント / 癌組織浸潤リンパ球 / 固形癌 / 癌免疫治療開発 / チロシンキナーゼ / 免疫寛容 / 癌浸潤リンパ球 / 癌微小環境 / 癌組織線維化 / 細胞性免疫能亢進 / CD8T細胞 / PTPN3 / ペプチドがんワクチン療法 / Tumor mutational burden / 免疫チェックポイント阻害薬 / がんゲノム / 腫瘍浸潤リンパ球 / 腫瘍遺伝子変異量 / がん微小環境 / Intercellular transmission / Artificial antigens / Gene transfer / Breast cancer / 伝達物質 / 遺伝子治療 / 細胞間伝達 / 人工抗原 / Regulatory T cells / Cancerous ascites / Immunotherapy / Small vesicles / 悪性腫瘍 / 免役療法 / 細胞小胞 / 癌性腹水 / 細胞小体 / artificial tissue / pancreas cancer / invasion / 3-dimension / microgravity / IFN-g / TGF-b / SMAD / スキルス / 人工がん組織 / 人工臓器 / 3次元培養 / 低重力 / warm ischemia / kidney transplantation / pancreas transplantation / 蛋白分解酵素阻害剤 / 温疎血 / 虚血再潅流障害 / 蛋白分解酵素 / 虚血再灌流障害 / 温阻血 / Intercellular molecular transfer / Antigen presenting cells / T lymphocytes / Tumor Immunoloav / 癌ワクチン療法 / 細胞間分子移動 / 抗原提示細胞 / リンパ球 / tumor immunity / higher immune system / artificial lymphoid tissue / 高次免疫組織 / 高次免疫システム / 人工リンパ組織 / 人工結合組織 / esophageal cancer / tumor marker / pathological examination / cancer-related factors / 早期癌 / 遺伝子 / 腫瘍増殖関連遺子 / 食道癌 / 腫瘍マーカー / 病理組織検査 / 腫瘍増殖関連遺伝子 / peritoneal trnasplantation / gene transfection / IFN-_γ / peritoneal carcinomtosis / artifical peritoneum / peritoneum / 中皮細胞 / INF-γ / 腹膜移植 / 腹膜 / kidney / pancreas / 膵腎同時移植 / 腎臓 / 膵臓 / 虚血・再潅流障害 / reconstruction therapy of immune surveillance system / peritoneal carcinosis / artificial immyne organ / artificial peritoneum / 人工免疫産生装置 / 腹膜播種モデル / 免疫監視機構構築療法 / 人工免疫組織 / telomerase / early pancreatic cancer / pancreatic cancer / テロメラーゼ / 早期膵癌 / Dissemination / Metastasis / Invasion / HGF antagonist / Biliary tract / Pancreas / Cancer / 腹膜播種 / HGFアンタゴニスト / 胆道癌 / 薬剤耐性 / 特異的 / γ-secretase / M集積 / G2 / Notch / g-secretase / 細胞増殖 / Nicastrin / Presenilin-2 / Presenilin-1 / ガンマセクレターゼ複合体 / 細胞周期 / 分子標的治療 / Taxane / GS 阻害剤 / gamma secretase (GS)複合体 / 大腸癌 / GM-CSF / IL-4 / IL-2 / Collagen / リンパ節 Less
  • Research Projects

    (30 results)
  • Research Products

    (130 results)
  • Co-Researchers

    (52 People)
  •  Development of a new cancer immunotherapy using the exosome derived from neoantigen pulsed mature dendritic cells

    • Principal Investigator
      永見 雅代 (梅林雅代)
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  オートファジー依存性がん抗原放出機構の解明および免疫提示システムの強化改変

    • Principal Investigator
      仲田 興平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  膵癌に対する抗腫瘍免疫抑制性環境の改変を目指したCAR-T療法の開発

    • Principal Investigator
      中村 雅史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kyushu University
  •  Analysis of a biological significance of PTPN3 expressed on dendritic cells for development of a new cancer immunotherapyPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  Development of therapy-resistant breast cancer treatment using neoantigen-reactive lymphocytes

    • Principal Investigator
      KUBO Makoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kyushu University
  •  Development of a new therapeutic strategy regulated Treg cells targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3)

    • Principal Investigator
      NAGAMI Masayo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  Neoantigen analysis in tumor tissues for development of personalized precision cancer immunotherapy

    • Principal Investigator
      KUBO Makoto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  Development of new therapeutical strategy for lung NET by inhibiting Hh/Notch signaling targeting RBPJPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Kyushu University
  •  Analysis of the mechanism of augmentation of random migration in lymphocytes and verification of the significance as a biomarker predicting therapeutic effect of immunotherapyPrincipal Investigator

    • Principal Investigator
      Morisaki Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  The development of the system estimating realtime antitumor activity of activated T lymphocytes in cancer immunotherapyPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Suppression of induction and accumulation at tumor site of regulatory T cells by inhibition of VEGF/VEGFR2 pathwayPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Identification and clinical application of colon cancer-specific gamma-secretase-targeting molecules

    • Principal Investigator
      YAMAGUCHI Kouji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of DC-based vaccine therapy by utilizing exosomes collected from healthy volunteer-derived DCsPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Development of the next generation cancer therapy using "Exosomes" by molecular tumor engineering technique

    • Principal Investigator
      KATANO Mitsuo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Development of the breast cancer therapy using intercellular transmission by small vesicle (Exosomes) having fusion faculty

    • Principal Investigator
      KUROKI Shouji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  腫瘍パルス樹状細胞の固相化培養装置を利用した腫瘍特異的リンパ球の培養と臨床応用Principal Investigator

    • Principal Investigator
      森崎 隆
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  生体外修飾を行った「再生免疫組織」による癌特異免疫療法への応用

    • Principal Investigator
      UCHIYAMA Akihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Irtercellular molecular transfer of OX40 in novel anti-tumor immunotherapy

    • Principal Investigator
      BABA Eishi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Experimental study of FR167653 in simultaneous pancreas and kidney transplantation from non-heart-beating donor

    • Principal Investigator
      SUGITANI Atushi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Development of artificial 3-dimensional cancer tissue model as tool for pathological analysis and therapeutic research for malignant solid tumor

    • Principal Investigator
      NOSHIRO Hirokazu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  A higher immune system model by combination of several types of artificial tissues (connective tissue, carcinoma tissue, and lymphoid tissue)

    • Principal Investigator
      KATANO Mitsuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Arificial biliary duct model for surgical therapeutic material and research material for biliary cancerPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  New therapy combined with immunology, molecular biology and medical technology for patients with peritoneal carcinosis

    • Principal Investigator
      KATANO Mitsuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Experimental study of FR167653 on ischemia- reperfusion injury in canine simultaneous pancreas and kidney transplantation from non-heart-beating donor

    • Principal Investigator
      SUGITANI Atushi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Artificial Peritoneum for Cancer Research and Surgical Treatment

    • Principal Investigator
      UCHIYAMA Akihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Clinical utilization of profiles of cancer-related factors in gastric and esophageal cancer

    • Principal Investigator
      NOSHIRO Hirokazu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Treatment of multiple oragn dysfunction syndrom : establisment of endothelial cell targetting therapyPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular diagnosis of pancreatic cancer by telomerase

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY
  •  New strategy against pancteato-biliary carcinoma using NK4, a four-kringle antagonist of hepatocyte growth factor

    • Principal Investigator
      TANAKA Masao
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Establisment of tumor vaccine using autologous dendritic cells and its application for addaptive immunotherapyPrincipal Investigator

    • Principal Investigator
      MORISAKI Takashi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KYUSHU UNIVERSITY

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All Journal Article Presentation Book

  • [Book] Immunotherapy of Cancer: An Innovative Treatment Comes of Age: Regulatory T Cells2016

    • Author(s)
      Hideya Onishi, Takashi Morisaki, Mitsuo Katano.
    • Total Pages
      358
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Book] Regulatory T cell: Immunotherapy of Cancer: An Innovative Treatment Comes of Age.2016

    • Author(s)
      Onishi H, Morisaki T, Katano M
    • Total Pages
      358
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Journal Article] TP53 and/or BRCA1 Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer2024

    • Author(s)
      Arimura Akiko、Sakai Kazuko、Kaneshiro Kazuhisa、Morisaki Takafumi、Hayashi Saori、Mizoguchi Kimihisa、Yamada Mai、Kai Masaya、Ono Mayumi、Nishio Kazuto、Nakamura Masafumi、Kubo Makoto
    • Journal Title

      Cancers

      Volume: 16 Issue: 6 Pages: 1184-1184

    • DOI

      10.3390/cancers16061184

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K27468
  • [Journal Article] Immunological analysis of hybrid peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.2023

    • Author(s)
      Morisaki S, Onishi H, Morisaki T, Kubo M, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Tsujimura K, Yoshimura S, Yew PY, Kiyotani K, Nakamura Y, Nakamura M, Kitazono T, Morisaki T.
    • Journal Title

      Front. Immunol

      Volume: 14 Pages: 1223331-1223331

    • DOI

      10.3389/fimmu.2023.1223331

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422, KAKENHI-PROJECT-23K27469
  • [Journal Article] Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma2023

    • Author(s)
      Nakamura S, Ohuchida K, Ohtsubo Y, Yamada Y, Tsutsumi C, Okuda S, Hisano K, Mochida Y, Shinkawa T, Iwamoto C, Torata N, Mizuuchi Y, Shindo K, Nakata K, Moriyama T, Torisu T, Nagai E, Morisaki T, Kitazono T, Oda Y, Nakamura M
    • Journal Title

      Clinical and Translational Medicine

      Volume: 13 Issue: 1

    • DOI

      10.1002/ctm2.1181

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07244, KAKENHI-PROJECT-22H00480, KAKENHI-PROJECT-20K07678, KAKENHI-PROJECT-20K09080, KAKENHI-PROJECT-21K19530, KAKENHI-PROJECT-21K16451, KAKENHI-PROJECT-22K07171, KAKENHI-PROJECT-21K08800, KAKENHI-PROJECT-22K16490
  • [Journal Article] MAML3 contributes to induction of malignant phenotype of gallbladder cancer through morphogenesis signaling under hypoxia.2023

    • Author(s)
      Na L, Onishi H, Morisaki S, Ichimiya S, Yamada Y, Masuda S, Nagao S, Koga S, Nakayama K, Imaizumi A, Oda Y, Nakamura M
    • Journal Title

      Anticancer Res

      Volume: 43(7) Issue: 7 Pages: 2909-2922

    • DOI

      10.21873/anticanres.16462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-23K08132, KAKENHI-PROJECT-23K08298, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-23K24422
  • [Journal Article] PTPN3 inhibition contributes to the activation of the dendritic cell function to be a promising new immunotherapy target2023

    • Author(s)
      Iwamoto N, Onishi H, Masuda S, Imaizumi A, Sakanashi K, Morisaki S, Nagao S, Koga S, Ozono K, Umebayashi M, Morisaki T, Nakamura M
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 149(16) Issue: 16 Pages: 14619-14630

    • DOI

      10.1007/s00432-023-05250-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-23K08073, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-23K24422
  • [Journal Article] C4orf47 contributes to the dormancy of pancreatic cancer under hypoxic condition.2023

    • Author(s)
      Nagao S, Onishi H, Kawamoto M, Masuda S, Na L, Morisaki S, Iwamoto N, Yamada Y, Koga S, Ichimiya S, Nakayama K, Imaizumi A, Nakashima K, Oda Y, Nakamura M
    • Journal Title

      J Cancer

      Volume: 14(2) Issue: 2 Pages: 306-317

    • DOI

      10.7150/jca.78993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-23K08132, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-23K24422
  • [Journal Article] Granzyme B Expression in the Tumor Microenvironment as a Prognostic Biomarker for Patients with Triple-Negative Breast Cancer2023

    • Author(s)
      Mizoguchi Kimihisa、Kawaji Hitomi、Kai Masaya、Morisaki Takafumi、Hayashi Saori、Takao Yuka、Yamada Mai、Shimazaki Akiko、Osako Tomofumi、Arima Nobuyuki、Okido Masayuki、Oda Yoshinao、Nakamura Masafumi、Kubo Makoto
    • Journal Title

      Cancers

      Volume: 15 Issue: 18 Pages: 4456-4456

    • DOI

      10.3390/cancers15184456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Journal Article] Contribution of pre-existing neoantigen-specific T cells to durable complete responses after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma2022

    • Author(s)
      Ichimiya S, Fujimura A, Masuda M, Masuda S, Yasumatsu R, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Yoshimura S, Onishi H, Nakamura M, Nakamura Y, Morisaki T
    • Journal Title

      Immunol Invest

      Volume: in press Issue: 5 Pages: 1498-1514

    • DOI

      10.1080/08820139.2021.1973491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-23K24422
  • [Journal Article] Significance of the Multi-gene Panel myRisk in Japan2022

    • Author(s)
      HAYASHI SAORI、KUBO MAKOTO、MATSUZAKI SAWAKO、KAI MASAYA、MORISAKI TAKAFUMI、YAMADA MAI、KANESHIRO KAZUHISA、TAKAO YUKA、SHIMAZAKI AKIKO、NAGAYOSHI KINUKO、MIZUUCHI YUSUKE、NAKAMURA MASAFUMI
    • Journal Title

      Anticancer Research

      Volume: 42 Issue: 8 Pages: 4097-4102

    • DOI

      10.21873/anticanres.15907

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
  • [Journal Article] Genetic medicine is accelerating in Japan2022

    • Author(s)
      Hayashi Saori、Kubo Makoto、Kaneshiro Kazuhisa、Kai Masaya、Yamada Mai、Morisaki Takafumi、Takao Yuka、Shimazaki Akiko、Shikada Sawako、Nakamura Masafumi
    • Journal Title

      Breast Cancer

      Volume: 印刷中 Issue: 4 Pages: 659-665

    • DOI

      10.1007/s12282-022-01342-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
  • [Journal Article] Lymph nodes as anti-tumor immunotherapeutic tool: intranodal tumor-specific antigen-pulsed dendritic cell vaccine immunotherapy2022

    • Author(s)
      Morisaki T, Morisaki T, Kubo M, Morisaki S, Nakamura Y, Onishi H
    • Journal Title

      Cancers

      Volume: 14(10) Issue: 10 Pages: 2438-2438

    • DOI

      10.3390/cancers14102438

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422
  • [Journal Article] Efficacy of intranodal neoantigen peptide-pulsed dendritic cell vaccine monotherapy in patients for advanced solid tumors; retrospective analysis.2021

    • Author(s)
      Morisaki T, Morisaki T, Kubo M, Onishi H, Hirano T, Morisaki S, Eto M, Monji K, Takeuchi A, Nakagawa S, Tanaka H, Koya N, Umebayashi M, Tsujimura K, Yew PY, Yoshimura S, Kiyotani K, Nakamura Y
    • Journal Title

      Anticancer Res

      Volume: 41(8) Issue: 8 Pages: 4101-4115

    • DOI

      10.21873/anticanres.15213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-21K08672
  • [Journal Article] PTPN3 is a potential target for a new cancer immunotherapy that has a dual effect of T cell activation and direct cancer inhibition in lung neuroendocrine tumor2021

    • Author(s)
      Koga S, Onishi H, Masuda S, Fujimura A, Ichimiya S, Nakayama K, Imaizumi A, Nishiyama K, Kojima M, Miyoshi K, Nakamura K, Umebayashi M, Morisaki T, Nakamura M
    • Journal Title

      Transl Oncol

      Volume: 14(9) Issue: 9 Pages: 101152-101152

    • DOI

      10.1016/j.tranon.2021.101152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-20K09180, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K09583
  • [Journal Article] Validity of the prognostication tool PREDICT version 2.2 in Japanese breast cancer patients2021

    • Author(s)
      Karen Zaguirre, Masaya Kai, Makoto Kubo, Mai Yamada, Kanako Kurata, Hitomi Kawaji, Kazuhisa Kaneshiro, Yurina Harada, Saori Hayashi, Akiko Shimazaki, Takafumi Morisaki, Hitomi Mori, Yoshinao Oda, Sanmei Chen, Taiki Moriyama, Shuji Shimizu, Masafumi Nakamura
    • Journal Title

      Cancer Medicine

      Volume: 10 Issue: 5 Pages: 1605-1613

    • DOI

      10.1002/cam4.3713

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19474, KAKENHI-PROJECT-18J20301, KAKENHI-PROJECT-18K08577
  • [Journal Article] Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites2020

    • Author(s)
      Morisaki Takashi、Hikichi Tetsuro、Onishi Hideya、Morisaki Takafumi、Kubo Makoto、Hirano Tatsuya、Yoshimura Sachiko、Kiyotani Kazuma、Nakamura Yusuke
    • Journal Title

      Immunological Investigations

      Volume: 13 Issue: 5 Pages: 1-18

    • DOI

      10.1080/08820139.2020.1778721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788
  • [Journal Article] Liprin-alphaa new therapeutic target for SCLC as an upstream mediator of HIF1alpha2019

    • Author(s)
      Onishi H, Yamasaki A, Nakamura K, Ichimiya S, Yanai K, Umebayashi M, Nagai S, Morisaki T
    • Journal Title

      Anticancer Research

      Volume: 39(3) Issue: 3 Pages: 1179-1184

    • DOI

      10.21873/anticanres.13227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04283, KAKENHI-PROJECT-16K10603, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788, KAKENHI-PROJECT-17K10792
  • [Journal Article] Patched 1-interacting Peptide Represses Fibrosis in Pancreatic Cancer to Augment the Effectiveness of Immunotherapy.2019

    • Author(s)
      Oyama Y, Onishi H, Koga S, Murahashi M, Ichimiya S, Nakayama K, Fujimura A, Kawamoto M, Imaizumi A, Umebayashi M, Ohuchida K, Morisaki T, Nakamura M
    • Journal Title

      J immunother

      Volume: In press Issue: 4 Pages: 121-133

    • DOI

      10.1097/cji.0000000000000305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-17K09464, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788
  • [Journal Article] Usefulness of the nCounter Analysis System to Monitor Immune-related Biomarkers in PBMCs During Anti-PD-1 Therapy2019

    • Author(s)
      MORISAKI TAKAFUMI、KUBO MAKOTO、UMEBAYASHI MASAYO、YUAN YUAN、TSUYADA AKIHIRO、TANAKA HIROTO、KOYA NORIHIRO、NAKAGAWA SHINICHIROU、MORISAKI TAKASHI、NAKAMURA MASAFUMI
    • Journal Title

      Anticancer Research

      Volume: 39 Issue: 8 Pages: 4517-4523

    • DOI

      10.21873/anticanres.13628

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08577, KAKENHI-PROJECT-19K09047
  • [Journal Article] PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody type immune checkpoint inhibitor.2019

    • Author(s)
      Fujimura A, Nakayama K, Imaizumi A, Kawamoto M, Oyama Y, Ichimiya S, Umebayashi M, Koya N, Morisaki T, Nakagawa T, Onishi H
    • Journal Title

      Cancer Immunol Immunother

      Volume: 68(10) Issue: 10 Pages: 1649-60

    • DOI

      10.1007/s00262-019-02403-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-17H04283
  • [Journal Article] RBPJ and MAML3: Potential therapeutic targets for small cell lung cancer.2018

    • Author(s)
      Onishi H, Ichimiya S, Yanai K, Umebayashi M, Nakamura K, Yamasaki A, Imaizumi A, Nagai S, Murahashi M, Ogata H, Morisaki T
    • Journal Title

      Anticancer Research

      Volume: 38(5) Issue: 8 Pages: 4543-4547

    • DOI

      10.21873/anticanres.12758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10792, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08788, KAKENHI-PROJECT-17H04283, KAKENHI-PROJECT-16K10603, KAKENHI-PROJECT-17K09464
  • [Journal Article] 患者さんを見据えた全人的癌治療―低酸素環境とHedgehog Signal―2017

    • Author(s)
      大西秀哉、荻野利達、森崎 隆、片野光男
    • Journal Title

      癌と化学療法

      Volume: 44 Pages: 977-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Journal Article] Stage IV gastric cancer successfully treated multidisciplinary therapy including immunotherapy: a case report.2017

    • Author(s)
      Kawamoto M, Onishi H, Koya N, Konomi H, Mitsugi K, Tanaka R, Motoshita J, Morisaki T, Nakamura M
    • Journal Title

      Surg Case Rep

      Volume: 3 Issue: 1 Pages: 112-112

    • DOI

      10.1186/s40792-017-0380-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05402, KAKENHI-PROJECT-15K10055, KAKENHI-PROJECT-16K15593, KAKENHI-PROJECT-17K09464
  • [Journal Article] Hedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes.2016

    • Author(s)
      Onishi H, Fujimura A, Oyama Y,Yamasaki A, Imaizumi A, Kawamoto M, Katano M, Umebayashi M, Morisaki T
    • Journal Title

      Cellular Immunology

      Volume: 310 Pages: 199-204

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Journal Article] Sugar-carrying Polystyrenes Facilitate Harvesting of APCs from MLRs: Possible Application of Sugar-carrying Polystyrenes to Immunotherapy.2016

    • Author(s)
      Imaizumi A, Onishi H, Yamasaki A, Kawamoto M, Morisaki T, Goto M, Iwama M, Akaike T, Hasumi K.
    • Journal Title

      Anticancer Research

      Volume: 36(2) Pages: 673-676

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Journal Article] NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors.2014

    • Author(s)
      Morisaki T, Hirano T, Koya N, Kiyota A, Tanaka H, Umebayashi M, Onishi H, Katano M
    • Journal Title

      Anticancer Res

      Volume: 34(8) Pages: 4529-4538

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] An epithelial cell adhesion molecule- and CD3 bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro.2014

    • Author(s)
      Umebayashi M, Kiyota A, Koya N, Tanaka H, Onishi H, Katano M, Morisaki T
    • Journal Title

      Anticancer Res

      Volume: 34(8) Pages: 4509-4520

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] Random Migration Contributes to Cytotoxicity of Activated CD8+ T-Lymphocytes but not NK cells.2014

    • Author(s)
      Onishi H, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M, Morisaki T
    • Journal Title

      Anticancer Res

      Volume: 34(8) Pages: 3947-3956

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer.2013

    • Author(s)
      Onishi H, Morisaki T, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: 62(6) Issue: 6 Pages: 1029-1039

    • DOI

      10.1007/s00262-013-1419-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591894, KAKENHI-PROJECT-24591908
  • [Journal Article] The Hedgehog inhibitor suppresses the function of monocyte-derived dendritic cells from patients with advanced cancer under hypoxia.2013

    • Author(s)
      Onishi H, Morisaki T, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 436(1) Issue: 1 Pages: 53-59

    • DOI

      10.1016/j.bbrc.2013.05.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591894, KAKENHI-PROJECT-24390303, KAKENHI-PROJECT-24591908
  • [Journal Article] Cancer immunotherapy using NKG2D and DNAM-1 systems.2012

    • Author(s)
      Morisaki T, Onishi H, Katano M
    • Journal Title

      Anticancer Research

      Volume: 32(6) Pages: 2241-2247

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] Inclusive estimation of complex antigen presentation functions of monocytederived dendritic cells differentiated under normoxia and hypoxia conditions2012

    • Author(s)
      Ogino T, Onishi H(6人中2番目), Morisaki T(4番目), Katano M(6番目) et al
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: 61 Pages: 409-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Inclusive estimation of complex antigen presentation functions of mono-cyte-derived dendritic cells differentiated under normoxia and hypoxia conditions2012

    • Author(s)
      Ogino T, Morisaki T, et al
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: 61 Issue: 3 Pages: 409-424

    • DOI

      10.1007/s00262-011-1112-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670, KAKENHI-PROJECT-23591894
  • [Journal Article] A new method for rapid cytotoxic T-lymphocyte induction using a multiple cytokine.2012

    • Author(s)
      Onishi H, Katano M, Morisaki T et al.
    • Journal Title

      Anticancer Research

      Volume: 32(6) Pages: 2385-2390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] Combining cetuximab with killer lymphocytes synergistically inhibits human.2012

    • Author(s)
      Morisaki T, Onishi H, Katano M et al.
    • Journal Title

      Anticancer Research

      Volume: 32(6) Pages: 2249-2256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Journal Article] Immunotherapy approaches targeting regulatory T-cells2012

    • Author(s)
      Onishi H, Morisaki T, Katano M.
    • Journal Title

      Anticancer Research

      Volume: 32 Pages: 997-1003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Combinatorial cytotoxicity of gemcitabine and cytokine-activate killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system2011

    • Author(s)
      Morisaki T, et al
    • Journal Title

      Anticancer Research

      Volume: 31 Pages: 2505-2510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Combinatorial cytotoxicity of gemcitabine and cytokine-activate killer cells in hepatocellular carcinoma via the NKG2DMICA/B system2011

    • Author(s)
      Morisaki T(9人中1番目), Onishi H(2番目), Katano M(9番目) et al
    • Journal Title

      Anticancer Research

      Volume: 31 Pages: 2505-2510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Vascular endothelial growth factor receptor 2 (VEGFR2) is selectively expressed by FOXP3hiehCD4+ regulatory T cells.2010

    • Author(s)
      Suzuki H, Morisaki T, Katano M, et al.
    • Journal Title

      European Journal of Immunology 40

      Pages: 197-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Treg制御による癌免疫療法2010

    • Author(s)
      片野光男、大西秀哉、森崎隆、鈴木宏往、荻野利達
    • Journal Title

      Surgery Frontier

      Volume: 17(3) Pages: 61-64

    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Treg制御による癌免疫療法2010

    • Author(s)
      片野光男、森崎隆, ほか
    • Journal Title

      Surgical Frontier

      Volume: 17 Pages: 259-262

    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] VEGFR2 is selectively expressed by FOXP3high CD4^+ Treg2010

    • Author(s)
      Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M.
    • Journal Title

      European Journal of Immunology

      Volume: 40 Pages: 197-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] A protein-bound polysaccharide, PSK, enhances tumor suppression induced by docetaxel in a gastric cancer xenograft model.2009

    • Author(s)
      Yamasaki A, Shoda M, Iijima H, Nagai S, Wada J, Suzuki H, Chikazawa N, Tasaka T, Kameda C, Tanaka H, Ikebe M, Jo E, Sato N, Nakamura M, Sekine F, Morisaki T, Katano M
    • Journal Title

      Anticancer Res 29

      Pages: 843-850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390361
  • [Journal Article] 制御性T細胞の基礎・臨床2009

    • Author(s)
      片野光男, 森崎隆, 他
    • Journal Title

      Biotherapy 22

      Pages: 197-214

    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] The contribution of vascular endothelial growth factor to the induction of regulatory T-cells in malignant effusions2009

    • Author(s)
      Wada J, Suzuki H, Fuchino R, Yamasaki A, Nagai S, Yanai K, Koga K, Nakamura M, Tanaka M, Morisaki T, Katano M.
    • Journal Title

      Anticancer Research

      Volume: 29 Pages: 881-888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] The contribution of vascular endothelial growth factor to the induction of regulatory T cells in malignant effusions2009

    • Author(s)
      Wada J, Morisaki T, Katano M, et al.
    • Journal Title

      Anticancer Research 29

      Pages: 881-888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591670
  • [Journal Article] Effects ofdocetaxelonantigen presentation- related functions of human monocyte-derived dendritic cells.2005

    • Author(s)
      Nakashima H, Tasaki A, Kubo M, Kuroki H, Matsumoto K, Tanaka M, Nakamura M, Morisaki T, Katano M.
    • Journal Title

      Cancer Immunol Pharmacol 55

      Pages: 479-487

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients.2005

    • Author(s)
      Onishi H, Morisaki T, Kuroki H, Matsumoto K, Baba E, Kuga H, Tanaka M, Katano M
    • Journal Title

      Anticancer Res 25

      Pages: 3445-3451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390351
  • [Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005

    • Author(s)
      Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M
    • Journal Title

      Cancer Immunol Immunother 54

      Pages: 468-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390351
  • [Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005

    • Author(s)
      Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M.
    • Journal Title

      Cancer Immunol Immunother 54

      Pages: 468-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Combination therapy of tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas.2005

    • Author(s)
      Katano M, Morisaki T, Koga K, Nakamura M, Onishi H, Matsumoto K, Tasaki A, Nakashima H, Akiyoshi T, Nakamura M.
    • Journal Title

      Anticancer Res 25

      Pages: 3771-3776

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Combination therapy of tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas.2005

    • Author(s)
      Katano M, Morisaki T, Koga K, Nakamura M, Onishi H, Matsumoto K, Tasaki A, Nakashima H, Akiyoshi T, Nakamura M
    • Journal Title

      Anticancer Res 25

      Pages: 3771-3776

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390351
  • [Journal Article] Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients.2005

    • Author(s)
      Onishi H, Morisaki T, Kuroki H, Matsumoto K, Baba E, Kuga H, Tanaka M, Katano M.
    • Journal Title

      Anticancer Res 25

      Pages: 3445-3451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591339
  • [Journal Article] Monocyte-derived dendritic cells that capture dead tumor cells secrete IL-12 and TNF-alpha through IL-12/ TNF-alpha/ NF-kappaB autocrine loop.2004

    • Author(s)
      Onishi H, Kuroki H, Matsumoto K, Haba.E, Sasaki N, Kuga H, Tanaka M, Katano M, Morisaki T.
    • Journal Title

      Cancer Immunol Immunother 53

      Pages: 1093-1100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Three-dimensional two-layer collagen matrix gel culture model for evaluating complex biological functions of monocyte-derived dendritic cells.2004

    • Author(s)
      Tasaki A, Yamanaka N, Kubo M, Matsumoto K, Kuroki H, Nakamura K, Nakahara C, Onishi H, Kuga H, Baba E, Tanaka M, Morisaki T, Katano M.
    • Journal Title

      J Immunol Methods 287(1-2)

      Pages: 79-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients : rationale, current progress, and perspectives2003

    • Author(s)
      Morisaki T et al.
    • Journal Title

      Human Cell 16

      Pages: 175-182

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients : rationale, current progress, and perspectives. Review.2003

    • Author(s)
      Morisaki T, Matsumoto K, Onishi H, Kuroki H, BabaE, Tasaki A, Kubo M, Nakamura M, Inaba S, Yamaguchi K, Tanaka M, Katano M.
    • Journal Title

      Hum Cell 16(4)

      Pages: 175-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Combined immunotherapy with intracavital injection of activated lymphocytes, monocyte-derived dendritic cells and low-dose2003

    • Author(s)
      Morisaki T et al.
    • Journal Title

      Anticancer Research 23

      Pages: 4459-4465

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Combination of adoptive immunotherapy with Herceptin for patients with HER2-expressing breast cancer.2003

    • Author(s)
      Kubo M, Morisaki T, Kuroki H, Tasaki A, Yamanaka N, Matsumoto K, Nakamura K, Onishi H, BabaE, Katano M.
    • Journal Title

      Anticancer Res. 23(6a)

      Pages: 4443-4449

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Cyclosporin-A enhances docetaxel-induced apoptosis through inhibition of nuclear factor-kB activation in human gastric carcinoma cells.2003

    • Author(s)
      Nakahara C, Nakamura K, Yamanaka N, Haba E, Wada M, Matsunaga H, Noshiro H, Tanaka M, Morisaki T, Katano M.
    • Journal Title

      Clin Cancer Res. 9(14)

      Pages: 5409-5416

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Combined immunotherapy with intracavital injection. of activated lymphocytes, monocyte-derived dendritic cells and low-dose OK-432 in patients with malignant effusion.2003

    • Author(s)
      Morisaki T, Matsumoto K, Kuroki H, Kubo M, Baba E, Onishi H, Tasaki A, Nakamura M, Inaba S, Katano M.
    • Journal Title

      Anticancer Res. 23(6a)

      Pages: 4459-4465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Streptococal preparation OX-432 : a new maturation factor of monocyte-derived dendritic cells for clinical use.2003

    • Author(s)
      Kuroki H, Morisaki T, Matsumoto K, Onishi H, Baba F, Tanaka M, Katano M.
    • Journal Title

      Cancer Immunol Immunother 52

      Pages: 561-568

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Dysfunctional and short-lived subsets in monocyte-derived dendritic cells from patients with advanced cancer2002

    • Author(s)
      Hideya Onishi, Takashi Morisaki, Eishi Baba, Hirotaka Kuga, Hideo Kuroki, Kotaro Matsumoto, Masao Tanaka, Mitsuo Katano
    • Journal Title

      Clin Immunol 105

      Pages: 286-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570417
  • [Journal Article] Regulatory T cells are possible effect prediction markers of immunotherapy for cancer patients

    • Author(s)
      Wada, J, Yamasaki, A, Morisaki, T, Nagai, S, Yanai, K, Fuchino, K, Akiyoshi, T, Koga, K, Nakashima, H, Nakamura, M, Tanaka, M, Katano, M
    • Journal Title

      Anticancer Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591440
  • [Presentation] 頭頚部癌に対するPTPN3阻害治療の検証2023

    • Author(s)
      益田昌吾、岩本直也、坂梨渓太、森崎晋史、糸山晋作、藤村晶子、大西秀哉
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] 乳癌患者とネオアンチゲン解析との関連性の検討2023

    • Author(s)
      溝口公久, 森崎隆史, 甲斐昌也, 高尾由佳, 山田舞, 島﨑亜希子, 林 早織, 茂地智子, 伊地知秀樹, 森崎隆, 吉住朋晴, 久保真, 中村雅史
    • Organizer
      第31回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Presentation] 樹状細胞ワクチンの免疫増幅における樹状細胞由来エクソソームの役割2023

    • Author(s)
      森崎晋史、森崎 隆、岩本直也、坂梨渓太、糸山晋作、益田昌吾、大西秀哉
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] 頭頸部癌に対する抗PD-1抗体薬治療におけるPTPN3阻害治療併用効 果の検証2023

    • Author(s)
      益田 昌吾、岩本 直也、森崎 晋史、那   琳、坂梨 渓太、糸山 晋作、 藤村 晶子、今泉  晃、大西 秀哉
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞におけるprotein tyrosine phosphatase non-receptor type 3 (PTPN3) 抑制により生じる抗腫瘍免疫への効果とその機序の考察2023

    • Author(s)
      岩本直也、大西秀哉、糸山晋作、坂梨渓太、森崎晋史、益田昌吾、森崎 隆、中村雅史、
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] 樹状細胞におけるprotein tyrosine phosphatase non-receptor type 3 (PTPN3)抑制により生じる抗腫瘍免疫への効果とその機序 の考察2023

    • Author(s)
      岩本 直也、大西 秀哉、坂梨 渓太、森崎 晋史、長尾晋次郎、益田 昌吾、 那   琳、森崎  隆、中村 雅史
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] MAML3 could be an inclusive suppressive factor for morphogenesis signaling-induced malignant phenotype of GBC.2023

    • Author(s)
      那 琳、大西秀哉、森崎晋史、益田昌吾、長尾晋次郎、岩本直也、坂梨渓太、中村雅史
    • Organizer
      第123回 日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 腫瘍遺伝子変異量(TMB):乳癌におけるバイオマーカーとしての意義2023

    • Author(s)
      久保真, 森崎隆史, 溝口公久, 中垣環, 馬場英司, 中村雅史
    • Organizer
      第31回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Presentation] 頭頚部癌に対するPTPN3阻害治療の検証2023

    • Author(s)
      益田昌吾、岩本直也、坂梨渓太、森崎晋史、糸山晋作、藤村晶子、大西秀哉
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] C4orf47は膵癌において低酸素環境での休眠に関与する2023

    • Author(s)
      長尾晋次郎、大西秀哉、坂梨渓太、森崎晋史、岩本直也、益田昌吾
    • Organizer
      第32回 日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞由来エクソソームによる免疫増幅の可能性2023

    • Author(s)
      森崎 晋史、森崎  隆、坂梨 渓太、岩本 直也、長尾晋次郎、 益田 昌吾、那   琳、大西 秀哉
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] 日本人乳癌患者の腸内細菌叢解析についての検討2023

    • Author(s)
      山田舞, 久保真, 甲斐昌也, 森崎隆史, 溝口公久, 高尾由佳, 林早織, 島崎亜希子, 古賀艶可, 落合百合菜, 茂地智子, 伊地知秀樹, 吉住朋晴, 中村雅史
    • Organizer
      第31回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Presentation] 樹状細胞におけるprotein tyrosine phosphatase non-receptor type 3 (PTPN3) 抑制により生じる抗腫瘍免疫への効果とその機序の考察2023

    • Author(s)
      岩本直也、大西秀哉、糸山晋作、坂梨渓太、森崎晋史、益田昌吾、森崎 隆、中村雅史、
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] Neoantigen pulsed dendritic cell vaccine therapy for prevention of postoperative recurrence or for recurrent cases of pancreatic cancer2023

    • Author(s)
      Koki Oyama, Kohei Nakata, Chika Iwamoto, Toshiya Abe, Naoki Ikenaga, Sachiko Yoshimura, Kazuma Kiyotani, Yusuke Nakamura, Hideya Onishi, Masafumi Nakamura, Takashi Morisaki
    • Organizer
      54th Annual American Pancreatic Association Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27673
  • [Presentation] 頭頚部癌における腫瘍微小環境を考慮した新たな治療標的分子の探索2023

    • Author(s)
      糸山晋作、益田昌吾、坂梨渓太、岩本直也、森崎晋史、大西秀哉
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 頭頸部癌に対する抗PD-1抗体薬治療におけるPTPN3阻害治療併用効 果の検証2023

    • Author(s)
      益田 昌吾、岩本 直也、森崎 晋史、那   琳、坂梨 渓太、糸山 晋作、 藤村 晶子、今泉  晃、大西 秀哉
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-23K08073
  • [Presentation] 樹状細胞ワクチンの免疫増幅における樹状細胞由来エクソソームの役割2023

    • Author(s)
      森崎晋史、森崎 隆、岩本直也、坂梨渓太、糸山晋作、益田昌吾、大西秀哉
    • Organizer
      第36回 日本バイオセラピィ学会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞由来エクソソームによる免疫増幅の可能性2023

    • Author(s)
      森崎 晋史、森崎  隆、坂梨 渓太、岩本 直也、長尾晋次郎、 益田 昌吾、那   琳、大西 秀哉
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞におけるprotein tyrosine phosphatase non-receptor type 3 (PTPN3)抑制により生じる抗腫瘍免疫への効果とその機序 の考察2023

    • Author(s)
      岩本 直也、大西 秀哉、坂梨 渓太、森崎 晋史、長尾晋次郎、益田 昌吾、 那   琳、森崎  隆、中村 雅史
    • Organizer
      第44回癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 頭頸部癌に対する抗 PD-1 抗体薬治療における PTPN3 阻害治療併用効果の検証2022

    • Author(s)
      益田昌吾、岩本直也、森崎晋史、長尾晋次郎、那琳、古賀智子、藤村晶子、今泉晃、大西秀哉
    • Organizer
      第43回 癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] シングルセルRNA sequencingシークエンシングを用いたHER2陽性乳癌治療抵抗性の網羅的遺伝子解析2022

    • Author(s)
      林 早織, 久保 真, 森 瞳美, 甲斐 昌也, 山田 舞, 金城 和寿, 森崎 隆史, 高尾 由佳, 島﨑 亜希子, 中村 雅史
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Presentation] HBOC診療の現状と課題2022

    • Author(s)
      久保 真, 鹿田 佐和子, 甲斐 昌也, 森崎 隆史, 木村 緑, 小川 昌宣, 加藤 聖子, 水内 祐介, 中村 雅史
    • Organizer
      第28回日本遺伝性腫瘍学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19532
  • [Presentation] 樹状細胞由来エクソソームから見た、抗原提示能およびネオアンチゲン特異的免疫反応誘導の検討2022

    • Author(s)
      森崎晋史、森崎隆、岩本直也、長尾晋次郎、益田昌吾、那琳、大西秀哉
    • Organizer
      第43回 癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 頭頸部癌における PTPN3 の生物学的意義の解析2022

    • Author(s)
      益田 昌吾、岩本 直也、坂梨 渓太、森崎 晋史、那 琳、長尾 晋次郎、藤村 晶子、大西 秀哉
    • Organizer
      第35回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞における protein tyrosine phosphatase non-receptor type 3(PTPN3)抑制により生じる抗腫瘍免疫への効果とその機序の考察2022

    • Author(s)
      岩本 直也、大西 秀哉、坂梨 渓太、森崎 晋史、長尾 晋次郎、益田 昌吾、那 琳、梅林 雅代、森崎 隆、中村 雅史
    • Organizer
      第35回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] チロシン脱リン酸化酵素PTPN3 を抑制する癌免疫治療の可能性2022

    • Author(s)
      岩本直也、大西秀哉、長尾晋次郞、古賀智子、梅林雅代、森崎隆、中村雅史
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] ネオアンチゲンワクチン療法における特異的免疫反応増幅への樹状細胞由来エクソソームの関与2022

    • Author(s)
      森崎 晋史1,2)、森崎 隆2)、岩本 直也1)、坂梨 渓太1)、中房 智樹1)、長尾 晋次郎1)、那 琳1)、益田 昌吾1)、大西 秀哉1
    • Organizer
      第35回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 頭頚部癌に対する抗 PD-1 抗体薬治療における PTPN3 阻害治療併用効果の検証2021

    • Author(s)
      益田 昌吾、古賀 智子、岩本 直也、長尾 晋次郎、那 琳、森崎 晋史、藤村 晶子、大西 秀哉
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] ネオアンチゲンペプチドパルス樹状細胞由来エクソソームによるネオアンチゲン特異的免疫反応誘導の可能性2021

    • Author(s)
      森崎 晋史、森崎 隆、吉村 祥子、大西 秀哉
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞における protein tyrosine phosphatase non-receptor type 3(PTPN3) 抑制により 生じる抗腫瘍免疫への効果2021

    • Author(s)
      岩本 直也、大西 秀哉、森崎 晋史、長尾 晋次郎、益田 昌吾、那 琳、古賀 智子、梅林 雅代、森崎 隆、中村 雅史
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 樹状細胞における protein tyrosine phosphatase non-receptor type 3(PTPN3) 抑制により 生じる抗腫瘍免疫への効果2021

    • Author(s)
      岩本 直也、大西 秀哉、森崎 晋史、長尾 晋次郎、益田 昌吾、那 琳、古賀 智子、梅林 雅代、森崎 隆、中村 雅史
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] ネオアンチゲンペプチドパルス樹状細胞由来エクソソームによるネオアンチゲン特異的免疫反応誘導の可能性2021

    • Author(s)
      森崎 晋史、森崎 隆、吉村 祥子、大西 秀哉
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] 頭頚部癌に対する抗 PD-1 抗体薬治療における PTPN3 阻害治療併用効果の検証2021

    • Author(s)
      益田 昌吾、古賀 智子、岩本 直也、長尾 晋次郎、那 琳、森崎 晋史、藤村 晶子、大西 秀哉
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] 胆嚢癌の新規治療法開発のための胆嚢癌における MAML3 の生物学的意義解析2021

    • Author(s)
      那 琳、大西 秀哉、一宮 脩、岩本 直也、長尾 晋次郎、益田 昌吾、森崎 晋史、古賀 智子 、中村 雅史
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] レンバチニブとネオアンチゲン療法で PR となった外耳道腺様嚢胞癌の一例2021

    • Author(s)
      藤村 晶子、益田 宗幸、大西 秀哉、森崎 隆
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-21K08672
  • [Presentation] 乳癌におけるネオアンチゲン解析の有用性2020

    • Author(s)
      久保真, 森崎隆史, 甲斐昌也, 梅林雅代, 島﨑亜希子, 林早織, 原田由利菜, 川地眸, 金城和寿, 倉田加奈子, 森瞳美, 山田舞, 森崎隆, 中村雅史
    • Organizer
      第28回日本乳癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08577
  • [Presentation] チロシン脱リン酸化酵素(PTPN3)は新規膵癌治療法の標的となりうる2020

    • Author(s)
      山崎章生、大西秀哉、梁井公輔、森崎 隆、中村雅史
    • Organizer
      第24回バイオ治療法研究会
    • Data Source
      KAKENHI-PROJECT-18K08788
  • [Presentation] 新規免疫チェックポイント分子PTPN3を標的とする癌治療の可能性2020

    • Author(s)
      藤村 晶子、益田 昌吾、古賀 智子、一宮 脩、中山 和典、 大山 康博、今泉 晃、森崎 隆、大西 秀哉
    • Organizer
      第33回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] マルチプレックス遺伝子パネルFoundationOne CDxが変えるHER2陽性乳癌の周術期治療2020

    • Author(s)
      久保真, 川地眸, 甲斐昌也, 山田舞, 倉田加奈子, 森 瞳美, 金城和寿, 本山由利菜, 林早織, 島﨑亜希子, 森崎隆史, 沖英次, 中村雅史
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K08577
  • [Presentation] 膵癌におけるTrkB/BDNFシグナルの生物学的意義解析2020

    • Author(s)
      大西秀哉、大山康博、那 琳、益田昌吾、長尾晋次郎、古賀智子、一宮 脩、藤岡 寛、中山和典、森崎 隆
    • Organizer
      第24回バイオ治療法研究会
    • Data Source
      KAKENHI-PROJECT-18K08788
  • [Presentation] Patched 1-interacting peptide represses fibrosis in pancreatic cancer to augment the effectiveness of immunotherapy2020

    • Author(s)
      村橋 睦了, 大山 康博 , 大西 秀哉 , 草森  浩輔 , 西川  元也 , 古賀 智子 , 一宮 脩 , 中山 和典, 藤村 晶子 , 川元 真 , 今泉 晃 , 梅林 雅代, 大内田 研宙 , 森崎 隆, 中村 雅史
    • Organizer
      第18回日本臨床腫瘍学会
    • Data Source
      KAKENHI-PROJECT-18K08788
  • [Presentation] 膵癌におけるTrkB/BDNFシグナルの生物学的意義解析2020

    • Author(s)
      大西秀哉、大山康博、那 琳、益田昌吾、長尾晋次郎、古賀智子、一宮 脩、藤岡 寛、中山和典、森崎 隆
    • Organizer
      第24回バイオ治療法研究会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] チロシン脱リン酸化酵素(PTPN3)は新規膵癌治療法の標的となりうる2020

    • Author(s)
      山崎章生、大西秀哉、梁井公輔、森崎 隆、中村雅史
    • Organizer
      第24回バイオ治療法研究会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] Tumor Mutational Burden in Japanese Patients with Triple Negative Breast Cancer2019

    • Author(s)
      Kurata K, Kubo M, Yuan Y, Harada Y, Morisaki T, Shimazaki A, Hayashi S, Kawaji H, Kaneshiro K, Yamada M, Kai M, Nakamura M
    • Organizer
      The 42nd San Antonio Breast Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08577
  • [Presentation] PTPN3を標的とした新規非抗体型免疫チェックポイント阻害治療の開発2019

    • Author(s)
      藤村晶子、中山和典、一宮 脩、大山康博、川元 真、森崎 隆、大西秀哉
    • Organizer
      第40回 癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] PTPN3を標的とした新規非抗体型免疫チェックポイント阻害治療の開発(第2報)2019

    • Author(s)
      藤村晶子、古賀智子、中山和典、一宮 脩、大山康博、森崎 隆、大西秀哉
    • Organizer
      第32回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] PD-L1 expression of tumor infiltrating immune cells has potential as a biomarker in triple-negative breast cancers2019

    • Author(s)
      Harada Y, Kubo M, Mori H, Kai M, Yamada M, Kurata K, Kawaji H, Kaneshiro K, Hayashi S, Shimazaki A, Morisaki T, Yamaguchi R, Arima N, Nishimura R, Okido M, Nakamura M
    • Organizer
      The 42nd San Antonio Breast Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08577
  • [Presentation] 乳癌におけるネオアンチゲン解析の意義2019

    • Author(s)
      森崎隆史、久保真、梅林雅代、吉村祥子、川地眸、倉田加奈子、金城和寿、森瞳、山田舞、林早織、本山由利菜、甲斐昌也、中村雅史、森崎隆
    • Organizer
      第32回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-18K08577
  • [Presentation] Ptch1結合ペプチドによる膵癌線維化抑制による免疫治療効果増強の検証2019

    • Author(s)
      大山康博、大西秀哉、古賀智子、一宮 脩、中山和典、藤村晶子、藤岡 寛、山崎章生、村橋睦了、森崎 隆、中村雅史
    • Organizer
      第32回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-19K09047
  • [Presentation] 抗PD-1抗体が著効した切除不能上顎洞癌の1例2017

    • Author(s)
      山崎章生、大西秀哉、藤村晶子、川元真、森崎隆
    • Organizer
      第21回バイオ治療法研究会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 活性化リンパ球のrandom migration能は癌免疫療法の効果予測因子となりうる2017

    • Author(s)
      川元 真 大西秀哉 山崎章生 森崎 隆 村橋睦了 緒方久修 中村雅史
    • Organizer
      第23回 国際個別化医療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 抗PD-1抗体が著効した切除不能上顎洞癌の一例2017

    • Author(s)
      藤村晶子、古後龍之介、森崎 隆、中川尚志、大西秀哉
    • Organizer
      第30回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 癌特異的な免疫監視機構の構築により良好な経過を得ているstage IV胃癌の1例2017

    • Author(s)
      川元 真、森崎 隆、大西秀哉
    • Organizer
      第72回 日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 活性化リンパ球における Hedgehog signal の生物学的意義の解析2016

    • Author(s)
      大西 秀哉、森崎 隆、山崎 章生、川元 真、中村 雅史
    • Organizer
      第37回 癌免疫外科研究会
    • Place of Presentation
      川越プリンスホテル(埼玉県・川越市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 免疫細胞療法と抗PD-1抗体でCRとなった耳下腺癌多発転移の一例2016

    • Author(s)
      藤村 晶子、大西 秀哉、益田 宗幸、中川 尚志、森崎 隆
    • Organizer
      第29回 日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      久留米シティプラザ(福岡県・久留米市)
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 低酸素環境下、活性化リンパ球および樹状細胞におけるHedgehogシグナルの生物学的役割の解析2016

    • Author(s)
      大西 秀哉、藤村 晶子、大山 康博、川元 真、山崎 章生、今泉 晃、中村 雅史、森崎 隆
    • Organizer
      第29回 日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      久留米シティプラザ(福岡県・久留米市)
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 活性化リンパ球のランダムマイグレーションと細胞傷害活性は関与するか2015

    • Author(s)
      大西 秀哉、森崎 隆、山崎 章生、川元 真、永井 英司、大内田 研宙、真鍋 達也、植木 隆、宮坂 義浩、大塚 隆生、中村 雅史
    • Organizer
      第77回 日本臨床外科学会総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 活性化リンパ球のランダムマイグレーションは癌免疫療法の効果増強の指標となり得るか2015

    • Author(s)
      大西 秀哉、森崎 隆、山崎 章生、川元 真、片野 光男、中村 雅史
    • Organizer
      第28回 日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      川越東武ホテル(埼玉県・川越市)
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 癌免疫細胞療法の治療効果予測バイオマーカーの探索:ランダムマイグレーション2015

    • Author(s)
      大西 秀哉、森崎 隆、山崎 章生、大内田 研宙、永井 英司、片野 光男、中村 雅史
    • Organizer
      第53回 日本癌治療学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-15K10055
  • [Presentation] 個別化免疫細胞療法確立への試み2014

    • Author(s)
      大西 秀哉、森崎 隆、梅林 雅代、古屋 雄大、田中 裕人、清田 章文、片野 光男
    • Organizer
      第35回癌免疫外科研究会
    • Place of Presentation
      シェラトン都ホテル大阪(大阪府・大阪市)
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Presentation] 制御性T細胞を標的としたテーラーメード消化器癌免疫療法2013

    • Author(s)
      大西 秀哉、森崎 隆、片野 光男
    • Organizer
      第68回日本消化器外科学会総会
    • Place of Presentation
      サンホテルフェニックス(宮崎市)
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Presentation] 免疫細胞療法テーラーメード化確立への試み2013

    • Author(s)
      大西 秀哉、森崎 隆、梅林 雅代、古屋 雄大、田中 裕人、清田 章文、片野 光男
    • Organizer
      第38回日本外科系連合学会
    • Place of Presentation
      ハイアットリージェンシー東京(東京都新宿区)
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Presentation] Hedgehogシグナル阻害剤は活性化リンパ球療法の効果を減弱する2013

    • Author(s)
      大西 秀哉、森崎 隆、清田 章文、梅林 雅代、古屋 雄大、田中 裕人、片野 光男
    • Organizer
      第26回日本バイオセラピィ学会
    • Place of Presentation
      いわて県民情報交流センターアイーナ(盛岡市)
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Presentation] 個別化(テ-ラーメード)癌免疫細胞療法と地域医療

    • Author(s)
      森崎 隆
    • Organizer
      第5回 福岡県医学会総会
    • Place of Presentation
      福岡県医師会館(福岡市)
    • Data Source
      KAKENHI-PROJECT-24591908
  • [Presentation] ジェムザール併用活性化リンパ球の臨床効果とそのメカニズムの検討

    • Author(s)
      森崎 隆、清田 章文、田中 裕人、梅林 雅代、古屋 雄大、大西 秀哉、片野 光男
    • Organizer
      第17回バイオ治療法研究会
    • Place of Presentation
      福岡大学病院・福大メディカルセンター(福岡市)
    • Data Source
      KAKENHI-PROJECT-24591908
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  岩本 千佳 (10752842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  竹中 克斗 (30301295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  村田 正治 (30304744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  大薗 慶吾 (60912847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  緒方 久修 (70432945)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  山下 智大 (30645635)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  肥川 和寛 (50941308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  池永 直樹 (90759755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 47.  KINOSHITA Moritoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  井上 重隆
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  KENJI Nakano
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 50.  永井 英司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  進藤 幸治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  陳 三妹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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