sonoda yukihiko 園田順彦

… Alternative Names

SONODA YUKIHIKO 園田順彦

SONODA Yukihiko 園田順彦

園田順彦ソノダユキヒコ

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Researcher Number	90302140
Other IDs
Affiliation (Current)	2025: 山形大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 山形大学, 大学院医学系研究科, 教授 2017: 山形大学, 医学部, 教授 2016: 山形大学, 大学院医学系研究科, 教授 2015: 山形大学, 医学(系)研究科(研究院), 教授 2014: 東北大学, 医学(系)研究科(研究院), 准教授 … More 2008 – 2011: Tohoku University, 病院, 講師 2010: Tohoku University, 大学院・医学系研究科, 非常勤講師 2005: 山形大, 医学部, 講師 2004: 山形大学, 医学部, 講師 2002 – 2003: 山形大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery
Keywords	Principal Investigator Glioblastoma / 膠芽腫 / PTEN / TERTp変異 / recurrence pattern / TERT / CD133 / 腫瘍幹細胞 / AKT / invasion … More / prognosis / methylation / TERT promoter / Methylation / CD44 / cancer stem cell / ADC / メチル化 / FLAIR / 遠隔再発 / Cancer stem cell / SVZ / distrant recurrence / multifocal / IDH / 生存期間 / 再発形式 / AICAR / グリオーマ / 幹細胞 / stem cell / glioma / CED / Temozolomide / ACNU / CED法 / MGMT / 薬剤耐性 / MGMT CED法 / chemoresistance / etoposide / VCR / CDDP / PI3K / mTOR / 悪性神経膠腫 / 神経膠腫 … More Except Principal Investigator CED法 / ミセル / 膠芽腫 / 薬物送達 / ミセル化抗癌剤 / テモゾロミド / Convection-enhanced delivery / グリオーマ / レチノイン酸 / 薬剤担体 / ドラッグデリバリー / 分化誘導療法 / 脳腫瘍 / 化学療法 / 脳腫瘍学 Less

Analysis of TERT promotor methylation statsu in glioblastomaPrincipal Investigator
- Principal Investigator
  
  園田順彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamagata University
Analysis of changes in expression of stem cell markers related to recurrent patterns of glioblastomaPrincipal Investigator
- Principal Investigator
  
  Sonoda Yukihiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamagata University
Identification of moleculamarkers for predicting recurrence pattern of glioblastomasPrincipal Investigator
- Principal Investigator
  
  Sonoda Yukihiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Yamagata University
Development of new therapy for glioblastoma using stem cell differentiating agentPrincipal Investigator
- Principal Investigator
  
  SONODA YUKIHIKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Yamagata University
  Tohoku University
Convection-enhanced delivery of micellar retinoic acid as a new treatment strategy for malignant glioma
- Principal Investigator
  
  KUMABE Toshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tohoku University
Convection-enhanced delivery of ACNU with systemic administration of temozolomidePrincipal Investigator
- Principal Investigator
  
  SONODA Yukihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tohoku University
Therapeutic effect of the polymeric micellar antineoplastic drugs infused convection-enhanced delivery against intracranial rat glioma models
- Principal Investigator
  
  YAMASHITA Yoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Miyagi Cancer Center Research Institute
悪性神経膠腫に対する抗腫瘍薬、PI3K阻害薬併用療法の効果Principal Investigator
- Principal Investigator
  
  園田順彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University
神経膠芽腫における、低酸素状態でのPTEN-AKT経路の役割―神経膠芽腫病態解明の為の基礎的研究―Principal Investigator
- Principal Investigator
  
  園田順彦
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University

All 2024 2023 2022 2021 2020 2018 2017 2016 2012 2011 2010 2009

All Journal Article Presentation Book Patent

[Book] Ischemic complication associated with resection of opercular gliomas2010
- Author(s)
  Kumabe T, Kanamori M, Saito R, Nagamatsu K, Sonoda Y, Higano S, Takahashi S, Tominaga T
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-21390401
[Book] Visualization of lateral lenticulostriate arteries using 3-tesla magnetic resonance imaging2010
- Author(s)
  Kumabe T, Saito R, Kanamori M, Sonoda Y, Higano S, Takahashi S, Tominaga T
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Association of ADC of hyperintense lesions on FLAIR images with TERT promoter mutation status in glioblastoma IDH wild type2024
- Author(s)
  Kamimura Shigeru、Mitobe Yuta、Nakamura Kazuki、Matsuda Kenichiro、Kanemura Yonehiro、Kanoto Masafumi、Futakuchi Mitsuru、Sonoda Yukihiko
- Journal Title
  
  Surgical Neurology International
  
  Volume: 15 Pages: 108-108
- DOI
  10.25259/sni_63_2024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07129, KAKENHI-PROJECT-20K09363
[Journal Article] Preoperative Apparent Diffusion Coefficient of Peritumoral Lesion Associate with Recurrence in Patients with Glioblastoma2022
- Author(s)
  松田憲一朗
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 62 Issue: 1 Pages: 28-34
- DOI
  10.2176/nmc.oa.2021-0182
- NAID
  130008141890
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18377, KAKENHI-PROJECT-20K09363
[Journal Article] Malignant Progression of an IDH Mutant Brainstem Glioma in Adult2021
- Author(s)
  SANO Kenshi、MATSUDA Ken-ichiro、KAWANAMI Kanako、KANEMURA Yonehiro、OHE Rintaro、SONODA Yukihiko
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 8 Issue: 1 Pages: 301-307
- DOI
  10.2176/nmccrj.cr.2020-0151
- NAID
  130008055890
- ISSN
  2188-4226
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09363
[Journal Article] Relationships between recurrence patterns and subventricular zone involvement or CD133 expression in glioblastoma.2020
- Author(s)
  Yamaki T, Shibahra I, Matsuda KI, Kanemura Y, Konta T, Kanamori M, Yamakawa M, Tominaga T, Sonoda Y.
- Journal Title
  
  J Neuro-oncol
  
  Volume: 146(3) Issue: 3 Pages: 489-499
- DOI
  10.1007/s11060-019-03381-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10856, KAKENHI-PROJECT-17K08736
[Journal Article] TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma2020
- Author(s)
  Kikuchi Z, Shibahara I, Yamaki T, Yoshioka E, Shofuda T, Ohe R, Matsuda KI, Saito R, Kanamori M, Kanemura Y, Kumabe T, Tominaga T, Sonoda Y.
- Journal Title
  
  Neurooncol Adv.
  
  Volume: 2 Issue: 1 Pages: 114-114
- DOI
  10.1093/noajnl/vdaa114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09363, KAKENHI-PROJECT-17K10856
[Journal Article] Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years.2018
- Author(s)
  Matsuda KI, Sakurada K, Nemoto K, Kayama T, Sonoda Y.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 21 Issue: 5 Pages: 820-825
- DOI
  10.1007/s10147-018-1298-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10856
[Journal Article] Local convection-enhanced delivery of an anti-CD40 agonistic monoclonal antibody induces antitumor effects in mouse glioma models.2016
- Author(s)
  Shoji T, Saito R, Chonan M, Shibahara I, Sato A, Kanamori M, Sonoda Y, Kondo T, Ishii N, Tominaga T.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 18(8) Issue: 8 Pages: 1120-8
- DOI
  10.1093/neuonc/now023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04945, KAKENHI-PROJECT-26282116, KAKENHI-PROJECT-26293319, KAKENHI-PROJECT-26462175
[Journal Article] Clinicopathological analysis of nine consecutive central nervous system primitive neuroectodermal tumors in a single institute2012
- Author(s)
  Aizawa-Kohama M, Kumabe T, Saito R, Kanamori M, Yamashita Y, Sonoda Y, Watanabe M, Tominaga T.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Preoperative evaluation of the deep cerebral veins using 3-tesla magnetic resonance imaging2011
- Author(s)
  Saito R, Kumabe T, Kanamori M, Yamashita Y, Sonoda Y, Higano S, Takahashi S, Tominaga T.
- Journal Title
  
  Minim Invasive Neurosurg
  
  Volume: 54(3) Pages: 105-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Regression of recurrent glioblastoma infiltrating the brainstem after convection-enhanced delivery of nimustine hydrochloride2011
- Author(s)
  Saito R, Sonoda Y, Kumabe T, Nagamatsu K, Watanabe M, Tominaga T
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 7 Issue: 5 Pages: 522-526
- DOI
  10.3171/2011.2.peds10407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249077, KAKENHI-PROJECT-21390401, KAKENHI-PROJECT-23791583
[Journal Article] New insights into glioma classification based on isocitrate dehydrogenase 1 and 2 gene status2011
- Author(s)
  Shibahara I, Sonoda Y, Kanamori M, Saito R, Kumabe T, Tominaga T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28 Issue: 3 Pages: 203-208
- DOI
  10.1007/s10014-011-0050-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249077, KAKENHI-PROJECT-21390401
[Journal Article] Logarithmic decrease of serum alpha-fetoprotein or human chorionic gonadotropin in response to chemotherapy can distinguish a subgroup with better prognosis among highly malignant intracranial non-germinomatous germ cell tumors2011
- Author(s)
  Kawaguchi T, Kumabe T, Kanamori M, Saito R, Yamashita Y, Sonoda Y, Watanabe M, Tominaga T.
- Journal Title
  
  J Neurooncol
  
  Volume: 104(3) Pages: 779-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Regression of recurrent glioblastoma infiltrating the brainstem after convection-enhanced delivery of nimustine hydrochloride2011
- Author(s)
  Saito R, Sonoda Y, Kumabe T, Nagamatsu K, Watanabe M, Tominaga T.
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 7(5) Pages: 522-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Infratentorial brain metastases of pediatric non-epithelial malignant tumors : three case reports2011
- Author(s)
  Osawa S, Kumabe T, Saito R, Sonoda Y, Niizuma H, Watanabe M, Tominaga T.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28(2) Pages: 167-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] New insights into glioma classification based on isocitrate dehydrogenase 1 and 2 gene status2011
- Author(s)
  Shibahara I, Sonoda Y, Kanamori M, Saito R, Kumabe T, Tominaga T.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28(3) Pages: 203-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas2011
- Author(s)
  Shibahara I, Sonoda Y, Kanamori M, Saito R, Yamashita Y, Kumabe T, Watanabe M, Suzuki H, Kato S, Ishioka C, Tominaga T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 6
- NAID
  10031155913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Combination chemotherapy with ifosfamide, cisplatin, and etoposide for medulloblastoma : single-institute experience and differences in efficacy for subgroups of medulloblastoma2011
- Author(s)
  Saito R, Kumabe T, Sonoda Y, Kanamori M, Yamashita Y, Watanabe M, Tominaga T.
- Journal Title
  
  Childs Nerv Syst
  
  Volume: 27(9) Pages: 1399-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Early detection of venous thromboembolism in patients with neuroepithelial tumor : efficacy of screening with serum D :-dimer measurements and Doppler ultrasonography2011
- Author(s)
  Kawaguchi T, Kumabe T, Kanamori M, Nakamura T, Saito R, Yamashita Y, Sonoda Y, Watanabe M, Tominaga T.
- Journal Title
  
  J Neurooncol
  
  Volume: 101(3) Pages: 495-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Local convection-enhanced delivery of chemotherapeutic agent transiently opens blood-brain barrier and improves efficacy of systemic chemotherapy in intracranial xenograft tumor model2011
- Author(s)
  Nakamura T, Saito R, Sugiyama S, Sonoda Y, Kumabe T, Tominaga T
- Journal Title
  
  Cancer Letter
  
  Volume: 310 Issue: 1 Pages: 77-83
- DOI
  10.1016/j.canlet.2011.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249077, KAKENHI-PROJECT-21390401, KAKENHI-PROJECT-23791583
[Journal Article] Combination chemotherapy with ifosfamide, cisplatin, and etoposide for medulloblastoma : single-institute experience and differences in efficacy for subgroups of medulloblastoma2011
- Author(s)
  Saito R, Kumabe T, Sonoda Y, Kanamori M, Yamashita Y, Watanabe M, Tominaga T
- Journal Title
  
  Childs Nerv Syst
  
  Volume: 27 Issue: 9 Pages: 1399-1406
- DOI
  10.1007/s00381-011-1485-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401, KAKENHI-PROJECT-23791583
[Journal Article] Preoperative evaluation of the deep cerebral veins using 3-tesla magnetic resonance imaging2011
- Author(s)
  Saito R, Kumabe T, Kanamori M, Yamashita Y, Sonoda Y, Higano S, Takahashi S, Tominaga T
- Journal Title
  
  Minim Invasive Neurosurg
  
  Volume: 54 Issue: 03 Pages: 105-109
- DOI
  10.1055/s-0031-1279715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401, KAKENHI-PROJECT-23791583
[Journal Article] Regression of Recurrent Brain Stem Glioblastoma Infiltrating the Brainstem after Convection-enhanced Delivery of Nimustine Hydrochloride.2011
- Author(s)
  Saito R, Sonoda Y, Kumabe T,Nagamatsu K, Watanabe M, Tominaga T.
- Journal Title
  
  Case report J Neurosurg in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390378
[Journal Article] Logarithmic decrease of serum alpha-fetoprotein or human chorionic gonadotropin in response to chemotherapy can distinguish a subgroup with better prognosis among highly malignant intracranial non-germinomatous germ cell tumors2011
- Author(s)
  Kawaguchi T, Kumabe T, Kanamori M, Saito R, Yamashita Y, Sonoda Y, Watanabe M, Tominaga T
- Journal Title
  
  J Neurooncol
  
  Volume: 104 Pages: 779-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Local convection-enhanced delivery of chemotherapeutic agent transiently opens blood-brain barrier and improves efficacy of systemic chemotherapy in intracranial xenograft tumor model2011
- Author(s)
  Nakamura T, Saito R, Sugiyama S, Sonoda Y, Kumabe T, Tominaga T.
- Journal Title
  
  Cancer Lett
  
  Volume: 310(1) Pages: 77-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Insulo-opercular gliomas : four different natural progression patterns and implications for surgical indications2010
- Author(s)
  Saito R, Kumabe T, Kanamori M, Sonoda Y, Tominaga T.
- Journal Title
  
  Neurol Med Chir(Tokyo)
  
  Volume: 50(4) Pages: 286-290
- NAID
  10026192192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Melanotic neuroectodermal tumor of the brain recurring 12 years after complete remission : case report2010
- Author(s)
  Omodaka S, Saito R, Kumabe T, Kawagishi J, Jokura H, Sonoda Y, Watanabe M, Kayama T, Tominaga T.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 50(4) Pages: 286-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts2010
- Author(s)
  Yokosawa M, Sonoda Y, Sugiyama S, Saito R, Yamashita Y, Nishihara M, Satoh T, Kumabe T, Yokoyama M, Tominaga T.
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 221(4) Pages: 257-64
- NAID
  10027085245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma.2010
- Author(s)
  Yukihiko Sonoda
- Journal Title
  
  Int J Clin Oncol. (In press)
- NAID
  10026601301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390378
[Journal Article] CDC25A mRNA levels significantly correlate with Ki-67 expression in human glioma samples.2010
- Author(s)
  Yamashita Y, Kasugai I, Sato M, Tanuma N, Sato I, Nomura M, Yamashita K, Sonoda Y, Kumabe T, Tominaga T, Katakura R, Shima H
- Journal Title
  
  J Neurooncol 100
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591730
[Journal Article] Dissemination limits the survival of patients with anaplastic ependymoma after extensive surgical resection, meticulous follow up, and intensive treatment for recurrence2010
- Author(s)
  Saito R, Kumabe T, Kanamori M, Sonoda Y, Tominaga T.
- Journal Title
  
  Neurosurg Rev
  
  Volume: 33(2) Pages: 185-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] he safety of combination chemotherapy with ifosfamide, cisplatin, and etoposide(ICE): single-institution retrospective review of 108 cases2010
- Author(s)
  Kanamori M, Kumabe T, Saito R, Yamashita Y, Sonoda Y, Tominaga T.
- Journal Title
  
  Shinkei Geka
  
  Volume: 38(11) Pages: 997-1005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma2010
- Author(s)
  Sonoda Y, Yokosawa M, Saito R, Kanamori M, Yamashita Y, Kumabe T, Watanabe M, Tominaga T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 15(4) Pages: 352-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma.2010
- Author(s)
  Sonoda Y, Yokosawa M, Saito R, Kanamori M, Yamashita Y, Kumabe T, Watanabe M, Tominaga T.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 4 Pages: 352-358
- NAID
  10026601301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390378
[Journal Article] Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.2010
- Author(s)
  Yokosawa M, Sonoda Y, Sugiyama S, Saito R, Yamashita Y, Nishihara M, Satoh T, Kumabe T, Yokoyama M, Tominaga T
- Journal Title
  
  Tohoku J Exp Med 221
  
  Pages: 257-264
- NAID
  10027085245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591730
[Journal Article] Imaging of hypoxic lesions in patients with gliomas by using positron emission tomography with 1-(2-[18F] fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole, a new 18F-labeled 2-nitroimidazole analog2010
- Author(s)
  Shibahara I, Kumabe T, Kanamori M, Saito R, Sonoda Y, Watanabe M, Iwata R, Higano S, Takanami K, Takai Y, Tominaga T.
- Journal Title
  
  J Neurosurg
  
  Volume: 113(2) Pages: 358-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma.2010
- Author(s)
  Sonoda Y, Yokosawa M, Saito R, Kanamori M, Yamashita Y, Kumabe T, Watanabe M, Tominaga T.
- Journal Title
  
  Int J Clin Oncol. 4
  
  Pages: 352-358
- NAID
  10026601301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390378
[Journal Article] Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.2010
- Author(s)
  Yokosawa M, Sonoda Y, Sugiyama S, Saito R, Yamashita Y, Nishihara M, Satoh T, Kumabe T, Yokoyama M, Tommaga T.
- Journal Title
  
  Thhoku J Exp Med.
  
  Volume: 221 Pages: 257-264
- NAID
  10027085245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Predictive factors for overall and progression-free survival, and dissemination in oligodendroglial tumors2009
- Author(s)
  Kanamori M, Kumabe T, Sonoda Y, Nishio Y, Watanabe M, Tominaga T
- Journal Title
  
  J Neurooncol
  
  Volume: 93 Pages: 219-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Analysis of IDH1 and IDH2 mutations in Japanese glioma patients2009
- Author(s)
  Sonoda Y, Kumabe T, Nakamura T, Saito R, Kanamori M, Yamashita Y, Suzuki H, Tominaga T.
- Journal Title
  
  Cancer Sci
  
  Volume: 100(10) Pages: 1996-8
- NAID
  10027196311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Therapeutic efficacy of a polymeric micellar doxorubicin infused by convection-enhanced delivery against intracranial 9L brain tumor models.2009
- Author(s)
  Inoue T, Yamashita Y, Nishihara M, Sugiyama S, Sonoda Y, Kumabe T, Yokoyama M, Tominaga T
- Journal Title
  
  Neuro Oncol 11
  
  Pages: 151-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591730
[Journal Article] Optimal treatment strategy for intracranial germ cell tumors : a single institution analysis2009
- Author(s)
  Kanamori M, Kumabe T, Saito R, Yamashita Y, Sonoda Y, Ariga H, Takai Y, Tominaga T.
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 4(6) Pages: 506-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Magnetic resonance imaging for preoperative identification of the lenticulostriate arteries in insular glioma surgery. Technical note2009
- Author(s)
  Saito R, Kumabe T, Inoue T, Takada S, Yamashita Y, Kanamori M, Sonoda Y, Tominaga T.
- Journal Title
  
  J Neurosurg
  
  Volume: 111(2) Pages: 278-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Intraoperative neuronavigation system without rigid pin fixation2009
- Author(s)
  Akamatsu Y, Kumabe T, Kanamori M, Nagamatsu K, Saito R, Sonoda Y, Sato K, Tominaga T.
- Journal Title
  
  No Shinkei Geka
  
  Volume: 37(12) Pages: 1193-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Collision tumor of anaplastic oligodendroglioma and gangliocytoma : a case report.2009
- Author(s)
  Takeuchi Y, Kanamori M, Kumabe T, Saito R, Sonoda Y, Watanabe M, Tominaga T.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 26(2) Pages: 89-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390401
[Journal Article] Long-term survivors of glioblastoma : clinical features and molecular analysis.2009
- Author(s)
  Sonoda Y, Kumabe T, Watanabe M, Nakazato Y, Inoue T, Kanamori M, Tominaga T.
- Journal Title
  
  Acta Neurochir (Wien). 151
  
  Pages: 1349-1358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390378
[Patent] 神経膠腫患者の予後の診断補助方法、及び、神経膠腫患者の予後診断キット2021
- Inventor(s)
  園田順彦
- Industrial Property Rights Holder
  園田順彦
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K09363
[Patent] 神経膠腫患者の予後の診断補助方法、及び、神経膠腫患者の予後診断キット2021
- Inventor(s)
  園田順彦
- Industrial Property Rights Holder
  園田順彦
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 悪性脳腫瘍と手術療法のフォアフロント2023
- Author(s)
  園田順彦
- Organizer
  日本脳神経外科学会　第82回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] DNA methylation of the TERT promoter associated with overall survival in GBM patients without TERT promoter mutation2023
- Author(s)
  Yukihiko Sonoda
- Organizer
  International conference of brain tumor reserach and therapy
- Invited
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 膠芽腫のTERT変異によるFLAIR高信号域のADCと病理組織像との関連2021
- Author(s)
  松田憲一朗　大江倫太郎　二口充　金村米博　園田順彦
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 膠芽腫のTERT変異によるFLAIR高信号域のADCと病理組織像との関連2021
- Author(s)
  松田憲一朗　大江倫太郎　二口充　金村米博　園田順彦
- Organizer
  第21回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 膠芽腫におけるTERTp変異の臨床的意義2020
- Author(s)
  菊池善彰　柴原一陽　山木哲　吉岡絵麻　正札智子　大江倫太郎　松田憲一朗　齋藤竜太　金森政之　金村米博　隈部俊宏　冨永悌二　園田順彦
- Organizer
  第38回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] TERTp野生型膠芽腫の臨床像2020
- Author(s)
  菊池善彰　金村米博　山木哲　松田憲一朗　金森政之　大江倫太郎　冨永悌二　園田順彦
- Organizer
  第38回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] WHO2017以後の悪性神経膠腫患者の正確な診断と予後予測2020
- Author(s)
  園田順彦
- Organizer
  第25回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 膠芽腫におけるTERTp変異の臨床的意義2020
- Author(s)
  菊池善彰　山木哲　柴原一陽　松田憲一朗　金村米博　大江倫太郎　金森政之　隈部俊宏　冨永悌二　園田順彦
- Organizer
  日本脳神経外科学会総会　第79回学術集会
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] WHO2017以後の悪性神経膠腫患者の正確な診断と予後予測2020
- Author(s)
  園田順彦
- Organizer
  第25回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] TERTp野生型膠芽腫の臨床像2020
- Author(s)
  菊池善彰　金村米博　山木哲　松田憲一朗　金森政之　大江倫太郎　冨永悌二　園田順彦
- Organizer
  第38回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-20K09363
[Presentation] 膠芽腫におけるTERTp変異の臨床的意義2020
- Author(s)
  菊池善彰　山木哲　柴原一陽　松田憲一朗　金村米博　大江倫太郎　金森政之　隈部俊宏　冨永悌二　園田順彦
- Organizer
  日本脳神経外科学会総会　第79回学術集会
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] 術前MRI画像分類の再発形式と予後予測に対する有用性2018
- Author(s)
  園田順彦
- Organizer
  第41回日本脳神経CI学会
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] 悪性神経膠腫の遠隔再発に関する研究　臨床研究から分子生物学的研究まで2017
- Author(s)
  園田順彦
- Organizer
  第18回分子脳神経外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] 膠芽腫の病態　－臨床医が行う研究ー2017
- Author(s)
  園田順彦
- Organizer
  第32回奈良脳神経ネットワーク研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10856
[Presentation] 腫瘍内での共刺激因子CD40刺激による新規脳腫瘍免疫治療法の開発2016
- Author(s)
  庄司拓大斎藤竜太長南雅志柴原一陽佐藤綾那金森政之園田順彦石井直人近藤亨冨永悌二
- Organizer
  第34回日本脳腫瘍学会学術総会
- Place of Presentation
  甲府富士屋ホテル（山梨県甲府市）
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-26462175
[Presentation] Safety and Feasibility of MRI guided convection-enhanced delivery of nimustine hydrochloride against recurrent glioma affecting brainstem2011
- Author(s)
  Saito R, Sonoda Y, Yamashita Y, Kanamori M, Kumabe T, Tominaga T.
- Organizer
  2011Society for Neurooncology Annual Meeting
- Place of Presentation
  Orange County, USA
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] MRI Guided Convection-Enhanced Delivery of Nimustine Hydrochloride Against Recurrent Glioma Affecting Brain Stem2011
- Author(s)
  Ryuta Saito, Yukihiko Sonoda, Yoji Yamashita, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga
- Organizer
  8th Annual World Congress of IBMISPS on Brain, Spinal Cord Mapping and Image Guided Therapy
- Place of Presentation
  San Francisco, U.S.A.
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] MRI Gmded Convection-Enhanced Delivery of Nimustine Hydrochloride Against Recurrent Glioma Affecting Brain Stem2011
- Author(s)
  Ryuta Saito, Yukihiko Sonoda, Yoji Yamashita, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga
- Organizer
  8th Annual World Congress of IBMISPS on Brain, Spinal Cord Mapping and Image Guided Therapy
- Place of Presentation
  San Francisco, U.S.A.
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] Convection-enhanced Delivery:現状と展望2011
- Author(s)
  斎藤竜太・園田順彦・隈部俊宏・冨永悌二
- Organizer
  第31回日本脳神経外科コングレス総会
- Place of Presentation
  横浜
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] 悪性神経膠腫に対するConvection-enhanced delivery :現状と展望2011
- Author(s)
  齋藤竜太、園田順彦、山下洋二、金森政之、隈部俊宏、冨永悌二
- Organizer
  第70回日本脳神経外科学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] MRI Guided Convection-Enhanced Delivery of Nimustine Hydrochloride Against Recurrent Glioma Affecting Brain Stem2011
- Author(s)
  Saito R, Sonoda Y, Yamashita Y, Kanamori M, Kumabe T, Tominaga T.
- Organizer
  8th Annual World Congress of IBMISPS on Brain, Spinal Cord Mapping and Image Guided Therapy
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] 悪性神経膠腫に対するConvection-enhanced delivery:現状と展望2011
- Author(s)
  齋藤竜太、園田順彦、山下洋二、金森政之、隈部俊宏、冨永悌二
- Organizer
  第70回日本脳神経外科学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] Logarithmic Decrease of Serum Alpha-Fetoprotein Level in Response to Chemotherapy can Distinguish the Subgroup with better Prognosis Among Highly Malignant Intracranial Non-Germinomatous Germ Cell Tumors2010
- Author(s)
  Kumabe T, Kawaguchi T, Saito R, Kanamori M, Yamashita Y, Sonoda Y, Watanabe M, Tominaga T
- Organizer
  ASNO2010 The 7th Meeting of Asian Society for Neuro
- Place of Presentation
  Oncology, Seoul
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] Imaging of hypoxic lesion in glioma patients by PET with [18F]FRP-170, a new 18F-labeled 2-nitroimidazole analog2010
- Author(s)
  Kumabe T, Shibahara I, Kanamori M, Saito R, Sonoda Y, Watanabe M, Iwata R, Higano S, Takanami K, Takai Y, Tominaga T
- Organizer
  18th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Travemunde, Germany
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] Local Application of Chemotherapeutics Transiently Opens Blood-Brain Barrier and Improves Efficacy of Systemic Chemotherapy against Intracranial Xenograft Tumor Model2010
- Author(s)
  Saito R, Nakamura T, Sonoda Y, Kumabe T, Tominaga T.
- Organizer
  2010Society for Neurooncology Annual Meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] Convection enhanced delivery of nimustine hydrochloride(ACNU)with systhemic administration of temozolomide in recurrent glioma patients2009
- Author(s)
  園田順彦
- Organizer
  World Federation Of Neuro-Oncology 2009
- Place of Presentation
  横浜
- Year and Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-20390378
[Presentation] モニタリングは神経膠腫の長期生存を向上させたか?(シンポジウム)2009
- Author(s)
  隈部俊宏、齋藤竜太、金森政之、山下洋二、園田順彦、冨永悌二
- Organizer
  社団法人日本脳神経外科学会第68回学術総会
- Place of Presentation
  東京
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21390401
[Presentation] テモゾロミド不応性再発神経膠腫に対するACNU局所投与2009
- Author(s)
  斎藤竜太, 園田順彦, 他
- Organizer
  第27回日本脳腫瘍学会
- Place of Presentation
  大阪
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-20390378

1. YAMASHITA Yoji (30420045)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. SAITO Ryuta (10400243)

# of Collaborated Projects: 2 results

# of Collaborated Products: 38 results
3. YOKOYAMA Masayuki (20220577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SHIMA Hiroshi (10196462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TANUMA Nobuhiro (40333645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NOMURA Miyuki (40390893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KUMABE Toshihiro (10250747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 40 results
8. 金森政之 (60420022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 富永悌二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 鹿戸将史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sonoda yukihiko 園田 順彦

SONODA YUKIHIKO 園田 順彦

SONODA Yukihiko 園田 順彦

園田 順彦 ソノダ ユキヒコ

Research Projects

Research Products

Co-Researchers

Analysis of TERT promotor methylation statsu in glioblastomaPrincipal Investigator

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Analysis of changes in expression of stem cell markers related to recurrent patterns of glioblastomaPrincipal Investigator

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Identification of moleculamarkers for predicting recurrence pattern of glioblastomasPrincipal Investigator

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Development of new therapy for glioblastoma using stem cell differentiating agentPrincipal Investigator

Principal Investigator

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Convection-enhanced delivery of micellar retinoic acid as a new treatment strategy for malignant glioma

Principal Investigator

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Convection-enhanced delivery of ACNU with systemic administration of temozolomidePrincipal Investigator

Principal Investigator

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Research Institution

Therapeutic effect of the polymeric micellar antineoplastic drugs infused convection-enhanced delivery against intracranial rat glioma models

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悪性神経膠腫に対する抗腫瘍薬、PI3K阻害薬併用療法の効果Principal Investigator

Principal Investigator

Project Period (FY)

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神経膠芽腫における、低酸素状態でのPTEN-AKT経路の役割―神経膠芽腫病態解明の為の基礎的研究―Principal Investigator

Principal Investigator

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[Book] Ischemic complication associated with resection of opercular gliomas2010

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[Book] Visualization of lateral lenticulostriate arteries using 3-tesla magnetic resonance imaging2010

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[Journal Article] Association of ADC of hyperintense lesions on FLAIR images with TERT promoter mutation status in glioblastoma IDH wild type2024

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DOI

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[Journal Article] Preoperative Apparent Diffusion Coefficient of Peritumoral Lesion Associate with Recurrence in Patients with Glioblastoma2022

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sonoda yukihiko 園田順彦

SONODA YUKIHIKO 園田順彦

SONODA Yukihiko 園田順彦

園田順彦ソノダユキヒコ