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Nangaku Masaomi  南学 正臣

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NANGAKU Masaomi  南学 正臣

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Researcher Number 90311620
Other IDs
External Links
Affiliation (Current) 2025: 東京大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help 2012 – 2024: 東京大学, 医学部附属病院, 教授
2011: 東京大学, 医学部附属病院, 特任講師
2009 – 2011: The University of Tokyo, 医学部附属病院, 講師
2008: The University of Tokyo, 医学部・附属病院, 特任講師
2008: 東京大学, 医学部・附属病院, 講師 … More
2008: The University of Tokyo, 医学部附属病院, 特任講師
2006 – 2007: The University of Tokyo, Faculty of Medicine, Research Associate, 医学部附属病院, 講師
2006: Tokyo University, School of Medicine, Assistant professor, 医学部, 講師
2002 – 2006: The University of Tokyo, School of Medicine, Assistant Researcher, 医学部附属病院, 助手
2005: 東京大学, 医学部, 助手
1999 – 2001: 東京大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 53040:Nephrology-related / Kidney internal medicine / Biological Sciences
Except Principal Investigator
Kidney internal medicine / Basic Section 52010:General internal medicine-related / Biological Sciences / Medium-sized Section 52:General internal medicine and related fields / Basic Section 53040:Nephrology-related / Neo-Gerontology / Gastroenterology / Kidney internal medicine
Keywords
Principal Investigator
低酸素 / 慢性腎臓病 / 腎不全 / HIF / 尿細管 / エピゲノム / 虚血 / 蛋白尿 / 補体調節蛋白 / 補体 … More / 糸球体腎炎 / 低酸素応答 / 線維化 / 炎症 / エピジェネティクス / エピジェネティックス / 腎臓学 / 糖尿病関連腎臓病 / CKD / ミトコンドリア / podocyte / 医工連携 / organ on chip / マイクロデバイス / エピジェネティック / エネルギー代謝 / HIF / chronic kidney failure / hypoxia / ischemia / gene transfer / renal tubular cell / proteinuria / glomerulonephritis / kidney failure / complement regulatory protein / complement / ノックアウトマウス / 遺伝子導入 / MESANGIUM / NEPHROTIC SYNDROME / RENAL TUBULES / PROTEINURIA / COMPLEMENT REGULATORY PROTEIN / COMPLEMENT / KIDNEY FAILURE / GLOMERULONEPHRITIS / メサンギウム / ネフローゼ / 有機ルミネッセンス / 酸素分圧 / りん光プローブ / 腎臓 / 低酸素シグナル / ストレス / 内科 / 低酸素センサー / エネルギー / 心臓病 / 肝臓病 / 生活習慣病 / 腎細胞癌 / ヒストン修飾 / 腫瘍 / 血管新生 … More
Except Principal Investigator
慢性腎臓病 / 低酸素 / 小胞体ストレス / HIF / 蛋白尿 / 尿細管上皮細胞 / アポトーシス / オルガネラ間相互作用 / オルガネラストレス / 腎臓老化 / 細胞骨格 / microRNA / 酸化ストレス / 糸球体足細胞 / 尿細管障害 / オルガネラコンタクトサイト / 脂質代謝 / エネルギー代謝 / 尿細管炎症 / 一次繊毛 / 尿細管間質障害 / 代謝リプログラミング / 尿細管細胞 / ATF6 / SASP / 細胞周期停止 / D-セリン / D-アミノ酸 / 近位尿細管上皮細胞 / 糖尿病性腎症 / hypoxia / Thrombotic micro-angiopathy / 酸素生物学 / イメージング / 細胞シグナル / 活性酸素種 / 酸素 / 尿毒素 / 糸球体腎炎 / ポドサイト / アクチン細胞骨格 / エピゲノム / 虚血再灌流モデル / 尿細管 / 翻訳制御 / リゾリン脂質 / 脂肪毒性 / 代謝 / 尿細管線炎症・維化 / 尿細管線維化 / 一次繊毛構成蛋白 / シスプラチン腎症 / 尿細管細胞一次繊毛 / 尿細管炎症・線維化 / IRF88 / 糖尿病関連腎臓病 / 小胞体 / ミトコンドリア / 一次繊毛 IRF88 / ヒストン / 線維化 / 尿細管間質 / 腎線維化 / ヒストン修飾 / 尿細管間質線維化 / 脂質毒性 / 急性腎不全 / cGAS-STING経路 / ミトコンドリアDNA / IFT88 / オルガネラクロストーク / 尿細管細胞代謝 / 尿細管脂質代謝 / ミトコンドリアストレス / 糖尿病性腎臓病 / 肥満関連腎症 / PHD阻害薬 / プロリン水酸化酵素 / 蛋白質恒常性 / 腎臓病態生理 / 尿細管老化 / マクロファージ / 2-デオキシグルコース / NF-κB / 尿細管間質傷害 / Mint3 / 解糖系 / 炎症 / metabolism / kidney / kidney fibrosis / Mitochondrial function / Fatty acid oxidation / Endoplasmic reticulum / UPR / Energy metabolism / Chronic kidney disease / センサー / microRNA 205 / アセチル化蛋白 / アクチン重合 / 糸球体濾過量 / cortactin / アセチル化 / SIRT1 / 翻訳後修飾 / TGF-β1 / 高グルコース / 次世代シークエンサー / バイオインフォマティクス / 補体 / 小児科学 / 腎臓内科 / 非典型溶血性尿毒症症候群 / 血栓性微小血管障害症 / diabetic nephropathy / brain protection / renoprotection / prolyl hydroxy lase / chronic hypoxia / angiogenesis / structure based drug design / hypoxia inducible factor / 脳保護 / 腎保護 / prolyl hydroxylase / 慢性虚血 / coagulated volume / development of liver tumors / tumor necrosis / microbubble / HIFU / 肝臓癌モデルrat / 経門脈的投与 / 焼灼体積 / 肺臓癌モデルrat / パルミチン酸 / 腫瘍壊死 / マイクロバブル / 強力集束超音波発信装置 / GFP rat / Chronic interstitial renal disease / Ischemic acute renal failure / HUVEC / Endothelial cell transplantation / Cell transplantation therapy / ヒト臍帯静脈欠陥内皮細胞 / Green fluorescent (GFP) rat / Green fluorescent protein (GFP) rat / 慢性間質性腎障害 / 虚血性急性腎不全 / ヒト臍帯静脈血管内皮細胞 / 血管内皮細胞移植 / 細胞治療 / ハイポキシア / 生体イメージング / インドール / インドキシル硫酸 / 腸内細菌 / ATF4 / 小胞体ストレス応答 / コータクチン / アクチン / ストレスシグナル / SIRT1 / 虚血・再灌流 / オートファジー / 腎臟病 / 酸化ストリス / UPR経路 / 腎臓病 / 虚血 / unfolded protein response / グルコース / 分子シャペロン / 腎臓学 / 糸球体 / PERK / eIF2α / GRP78 / 蛋白翻訳抑制因子 / Thy-1腎炎 / ER chaperone / ER stress preconditioning / 糸球体障害 / Thy-1 腎炎 / 小胞体シャペロン / Unfolded protein response / Endoplasmic reticulum stress preconditioning Less
  • Research Projects

    (35 results)
  • Research Products

    (654 results)
  • Co-Researchers

    (75 People)
  •  HIFの活性化の腎臓における細胞特異的影響の解明Principal Investigator

    • Principal Investigator
      南学 正臣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      The University of Tokyo
  •  Novel tubular homeostatic mechanism mediated by primary cilia

    • Principal Investigator
      Inagi Reiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      The University of Tokyo
  •  Pathophysiological role of organelle contact site in tubular homeostasis

    • Principal Investigator
      Inagi Reiko
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  ヒストン修飾阻害薬GSKJ4による腎尿細管間質線維化の病態解明

    • Principal Investigator
      三村 維真理
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of organelle crosstalk on organ homeostasis in aging and disease

    • Principal Investigator
      Inagi Reiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      The University of Tokyo
  •  Elucidation of metabolic reprogramming in the kidney and development of novel therapeutic approaches utilizing HIF against kidney diseasePrincipal Investigator

    • Principal Investigator
      Nangaku Masaomi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      The University of Tokyo
  •  Therapeutic intervention of CKD targeting cellular oxygen sensors

    • Principal Investigator
      Tanaka Tetsuhiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of novel therapeutic approaches targeting ATF6-mediated metabolic alteration

    • Principal Investigator
      饒 梓明
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of Novel Therapy for Renal Diseases Targeting Macrophage Metabolic Reprogramming

    • Principal Investigator
      Kawakami Takahisa
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyorin University
      The University of Tokyo
  •  Establishment of innovative culture system, kidney-on-chip, utilizing microdevicePrincipal Investigator

    • Principal Investigator
      Nangaku Masaomi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Pathophysiological role of D-amino acid on proteostasis in the kidney

    • Principal Investigator
      Reiko Inagi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Establishment of whole exome sequencing for the diagnosis of atypical hemolytic uremic syndrome

    • Principal Investigator
      Kato Hideki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Mechanisms of maintenance of podocyte cytoskeletal structure against metabolic stress associated with diabetes and Development of novel therapeutic strategies

    • Principal Investigator
      WADA Takehiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokai University
  •  Epigenetic regulation of endoplasmic reticulum stress signal in aging of kidney

    • Principal Investigator
      Inagi Reiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neo-Gerontology
    • Research Institution
      The University of Tokyo
  •  Promotion of oxygen biology on the basis of international networks

    • Principal Investigator
      Mori Yasuo
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Metabolic Reprogramming and Hypoxic Memory in Kidney DiseasePrincipal Investigator

    • Principal Investigator
      Nangaku Masaomi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Oxygen biology: a new criterion for integrated understanding of life

    • Principal Investigator
      Mori Yasuo
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  ;The roles of hypoxia signaling in the pathogenesis of lifestyle related diseasesPrincipal Investigator

    • Principal Investigator
      Nangaku Masaomi
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Regulation of hypoxia inducible genes in chronic kidney disease

    • Principal Investigator
      TANAKA Tetsuhiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of the methodology to evaluate oxygenation of organs in vivo utilizing organic luminescencePrincipal Investigator

    • Principal Investigator
      Nangaku Masaomi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Identification of microRNA that regulates renal pathophysiology related to hypoxia and ER stress

    • Principal Investigator
      Inagi Reiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  The analysis of the pathophysiology of the Kidney- Gut interaction, the vicious cycle in Chronic kidney disease and dysbiosis.

    • Principal Investigator
      Ohse Takamoto
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the pathogenesis of kidney disease via epigenetic responses against hypoxiaPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanisms of podocyte homeostasis and development of new therapeutic strategies against diabetic kidney disease

    • Principal Investigator
      WADA Takehiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Expression profile of miRNA in chronic kidney disease and identification of miRNA regulating hypoxia and endoplasmic reticulum stress signals

    • Principal Investigator
      INAGI Reiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the pathophysiology of chronic kidney disease by comprehensive analysis of the hypoxia-responsive transcriptional networkPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanisms underlying podocyte injury through endoplasmic reticulum stress and Development of novel therapeutic strategies for glomerular diseases

    • Principal Investigator
      WADA Takehiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Comprehensive functional analysis and application of responses against hypoxia in the kidneyPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Pathophysiological contribution of endoplasmic reticulum stress in the kidney

    • Principal Investigator
      INAGI Reiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of novel compounds that enhance HIF activity and ameliorate chronic hypoxia in diabetic nephropathy and other diseases.

    • Principal Investigator
      MIYATA Toshio
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokai University
  •  Analysis of hypoxia-responsive genes and establishment of markers of ischemic injuryPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Using microbubbles to increase the destruction of liver tumors by high-intensity focused ultrasound

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Investigation of transplantation cell therapy for acute renal endothelial cell injury.

    • Principal Investigator
      NOIRI Eisei
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Functional analysis of complement regulatory proteins in glomerulonephritis and development of novel therapeutic approachesPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  INVESTIGATION OF ROLES OF COMPLEMENT REGULATORY PROTEINS IN THE KIDNEY AND THEIR THERAPEUTIC USEPrincipal Investigator

    • Principal Investigator
      NANGAKU Masaomi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      UNIVERSITY OF TOKYO

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Other

  • [Book] 腎臓内科 レジデントマニュアル2015

    • Author(s)
      加藤 秀樹、南学 正臣
    • Total Pages
      720
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Book] 内科疾患の診断基準・病型分類・重症度2015

    • Author(s)
      吉田 瑶子、加藤 秀樹、南学 正臣
    • Total Pages
      1388
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Book] 腎機能低下時の薬剤ポケットマニュアル2015

    • Author(s)
      南学正臣(編集)、和田健彦、加藤秀樹、田中哲洋他
    • Total Pages
      380
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Book] Annual Review 腎臓2014

    • Author(s)
      岡田啓、和田健彦、南学正臣
    • Total Pages
      7
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Book] CKDブックー慢性腎臓病管理の手引ー2013

    • Author(s)
      南学正臣、和田健彦、花房規男(翻訳)他
    • Total Pages
      640
    • Publisher
      メディカル・サイエンス・インターナショナル
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Book] AGEsと老化―糖化制御からみたウェルエイジングー2013

    • Author(s)
      城愛理, 稲城玲子, 南学正臣
    • Total Pages
      278
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25461207
  • [Book] AGEsと老化-糖化制御からみたウェルエイジングー2012

    • Author(s)
      城愛理、稲城玲子、南学正臣
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-22590880
  • [Book] 内分泌・糖尿病・代謝内科2011

    • Author(s)
      稲城玲子、南学正臣
    • Total Pages
      160
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-22590880
  • [Book] Oxidative Stress in Applied Basic Research and Clinical Practice : Studies on Renal Disorders.2011

    • Author(s)
      Miyata, Eckardt, Nangaku
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Book] Oxidative Stress in Applied Basic Research and Clinical Practice2010

    • Author(s)
      Miyata T, Eckardt KU, Nangaku M
    • Total Pages
      783
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Book] Oxidative Stress in Applied Basic Research and Clinical Practice : Studies on Renal Disorders2010

    • Author(s)
      Miyata T, Eckardt KU, Nangaku M
    • Total Pages
      783
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Book] CKDに伴う貧血2009

    • Author(s)
      稲城玲子、南学正臣
    • Publisher
      医薬ジャーナル社(印刷中)
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Book] 薬局 : 病気と薬の説明ガイド20072007

    • Author(s)
      稲城玲子, 南学正臣
    • Total Pages
      1327
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Book] 薬局:病気と薬の説明ガイド20072007

    • Author(s)
      稲城 玲子、南学 正臣
    • Total Pages
      1327
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Book] 薬局:病気と薬の説明ガイド20072007

    • Author(s)
      稲城玲子、南学正臣
    • Total Pages
      1327
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Book] CKDに伴う貧血

    • Author(s)
      稲城玲子, 南学正臣
    • Publisher
      医薬ジャーナル(印刷中)
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Uremia impedes skeletal myocyte myomixer expression and fusogenic activity: implication for uremic sarcopenia2024

    • Author(s)
      Takaaki Higashihara, Motoki Odawara, Hiroshi Nishi, Takehito Sugasawa, Yumika Suzuki, Satoshi Kametaka, Reiko Inagi, Masaomi Nangaku
    • Journal Title

      The American Journal of Pathology

      Volume: 194 Issue: 5 Pages: 759-771

    • DOI

      10.1016/j.ajpath.2024.01.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08222, KAKENHI-PROJECT-21H02824
  • [Journal Article] Hypoxia‐inducible lncRNA MIR210HG promotes HIF1α expression by inhibiting miR‐93‐5p in renal tubular cells2023

    • Author(s)
      Saigusa Hanako、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      The FEBS Journal

      Volume: 290 Issue: 16 Pages: 4040-4056

    • DOI

      10.1111/febs.16794

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
  • [Journal Article] Acetate attenuates kidney fibrosis in an oxidative stress‐dependent manner2023

    • Author(s)
      Kawabata Chiaki、Hirakawa Yosuke、Inagi Reiko、Nangaku Masaomi
    • Journal Title

      Physiological Reports

      Volume: 11 Issue: 14

    • DOI

      10.14814/phy2.15774

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08348, KAKENHI-PROJECT-21H02824
  • [Journal Article] Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia2023

    • Author(s)
      Yamazaki Tomotaka、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Physiological Reports

      Volume: 11 Issue: 17

    • DOI

      10.14814/phy2.15810

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
  • [Journal Article] International Society of Nephrology first consensus guidance for preclinical animal studies in translational nephrology2023

    • Author(s)
      Nangaku M, Kitching AR, Boor P, Fornoni A, Floege J, Coates PT, Himmelfarb J, Lennon R, Anders HJ, Humphreys BD, Caskey FJ, Fogo AB; TRANSFORM group.
    • Journal Title

      Kidney International

      Volume: S0085-2538(23)00174-6 Issue: 1 Pages: 36-45

    • DOI

      10.1016/j.kint.2023.03.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21H02824
  • [Journal Article] Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection2023

    • Author(s)
      Nakamura Yasuna、Matsumoto Hirotaka、Wu Chia-Hsien、Fukaya Daichi、Uni Rie、Hirakawa Yosuke、Katagiri Mikako、Yamada Shintaro、Ko Toshiyuki、Nomura Seitaro、Wada Youichiro、Komuro Issei、Nangaku Masaomi、Inagi Reiko、Inoue Tsuyoshi
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 666-666

    • DOI

      10.1038/s42003-023-05051-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-23K22779, KAKENHI-PROJECT-23K24350
  • [Journal Article] Epigenetic regulation of angiogenesis and ischemic response by long noncoding RNA LEENE in diabetes2023

    • Author(s)
      Mimura Imari、Nangaku Masaomi
    • Journal Title

      Kidney International

      Volume: 104 Issue: 6 Pages: 1048-1050

    • DOI

      10.1016/j.kint.2023.06.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08604
  • [Journal Article] Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal tubular cells via exchange of histone variant H2A.Z. for H2A2023

    • Author(s)
      Miura Rika、Mimura Imari、Saigusa Hanako、Yamazaki Tomotaka、Tanemoto Fumiaki、Kurata Yu、Sato Dai、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 13235-13235

    • DOI

      10.1038/s41598-023-40540-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
  • [Journal Article] Epigenetic memory contributing to the pathogenesis of AKI-to-CKD transition2022

    • Author(s)
      Fumiaki Tanemoto, Masaomi Nangaku, Imari Mimura
    • Journal Title

      Frontiers in Molecular Biosciences

      Volume: 21 Pages: 1003227-1003227

    • DOI

      10.3389/fmolb.2022.1003227

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08604
  • [Journal Article] Effect of M2-like macrophages of the injured-kidney cortex on kidney cancer progression2022

    • Author(s)
      Taisuke Ishii, Imari Mimura, Koji Nagaoka, Akihiro Naito, Takehito Sugasawa, Ryohei Kuroda, Daisuke Yamada, Yasuharu Kanki, Haruki Kume, Tetsuo Ushiku, Kazuhiro Kakimi, Tetsuhiro Tanaka, Masaomi Nangaku
    • Journal Title

      Cell Death Discovery

      Volume: 5 Issue: 1 Pages: 480-480

    • DOI

      10.1038/s41420-022-01255-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20H03432, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-20K09161
  • [Journal Article] Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease2022

    • Author(s)
      Yoshioka Kentaro、Hirakawa Yosuke、Kurano Makoto、Ube Yuko、Ono Yoko、Kojima Kensuke、Iwama Taiga、Kano Kuniyuki、Hasegawa Sho、Inoue Tsuyoshi、Shimada Takashi、Aoki Junken、Yatomi Yutaka、Nangaku Masaomi、Inagi Reiko
    • Journal Title

      Kidney International

      Volume: 101 Issue: 3 Pages: 510-526

    • DOI

      10.1016/j.kint.2021.10.039

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159
  • [Journal Article] Potential progression biomarkers of diabetic kidney disease determined using comprehensive machine learning analysis of non-targeted metabolomics2022

    • Author(s)
      Hirakawa Yosuke、Yoshioka Kentaro、Kojima Kensuke、Yamashita Yasuho、Shibahara Takuma、Wada Takehiko、Nangaku Masaomi、Inagi Reiko
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 16287-16287

    • DOI

      10.1038/s41598-022-20638-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08321, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439
  • [Journal Article] CKMの国際動向(解説)2022

    • Author(s)
      東原 崇明, 稲城 玲子, 南学 正臣
    • Journal Title

      腎臓内科

      Volume: 15 Pages: 429-435

    • Data Source
      KAKENHI-PROJECT-21K19439
  • [Journal Article] CKMの国際動向(解説)2022

    • Author(s)
      東原 崇明, 稲城 玲子, 南学 正臣
    • Journal Title

      腎臓内科

      Volume: 15 Pages: 429-435

    • Data Source
      KAKENHI-PROJECT-21H02824
  • [Journal Article] Bone marrow stromal cell antigen-1 (CD157) regulated by sphingosine kinase 2 mediates kidney fibrosis2022

    • Author(s)
      Inoue T, Nakamura Y, Tanaka S, Kohro T, Li LX, Huang L, Yao J, Kawamura S, Inoue R, Nishi H, Fukaya D, Uni R, Hasegawa S, Inagi R, Umene R, Wu CH, Ye H, Bajwa A, Rosin DL, Ishihara K, Nangaku M, Wada Y, Okusa MD
    • Journal Title

      Frontiers in Medicine

      Volume: 9 Pages: 993698-993698

    • DOI

      10.3389/fmed.2022.993698

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08222, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-23K24350
  • [Journal Article] Activation of α7 nicotinic acetylcholine receptors attenuates monocyte endothelial adhesion through FUT7 inhibition2022

    • Author(s)
      Wu Chia-Hsien、Inoue Tsuyoshi、Nakamura Yasuna、Uni Rie、Hasegawa Sho、Maekawa Hiroshi、Sugahara Mai、Wada Youichiro、Tanaka Tetsuhiro、Nangaku Masaomi、Inagi Reiko
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 590 Pages: 89-96

    • DOI

      10.1016/j.bbrc.2021.12.094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16107
  • [Journal Article] Decreased IFT88 expression with primary cilia shortening causes mitochondrial dysfunction in cisplatin-induced tubular injury2021

    • Author(s)
      Fujii Rie、Hasegawa Sho、Maekawa Hiroshi、Inoue Tsuyoshi、Yoshioka Kentaro、Uni Rie、Ikeda Yoichiro、Nangaku Masaomi、Inagi Reiko
    • Journal Title

      American Journal of Physiology-Renal Physiology

      Volume: 321 Issue: 3 Pages: F278-F292

    • DOI

      10.1152/ajprenal.00673.2020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159
  • [Journal Article] A novel method for successful induction of interdigitating process formation in conditionally immortalized podocytes from mice, rats, and humans2021

    • Author(s)
      Doi Kotaro、Kimura Hiroshi、Wada Takehiko、Tanaka Tetsuhiro、Hiromura Keiju、Saleem Moin A.、Inagi Reiko、Nangaku Masaomi、Fujii Teruo
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 570 Pages: 47-52

    • DOI

      10.1016/j.bbrc.2021.07.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H01849, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439
  • [Journal Article] β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice2021

    • Author(s)
      Takaaki Higashihara、Hiroshi Nishi、Koji Takemura、Hiroshi Watanabe、Toru Maruyama、Reiko Inagi、Tetsuhiro Tanaka、Masaomi Nangaku
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 9130-9130

    • DOI

      10.1038/s41598-021-88438-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439
  • [Journal Article] Treatment of Diabetic Kidney Disease: Current and Future2021

    • Author(s)
      Tomotaka Yamazaki, Imari Mimura, Tetsuhiro Tanaka, Masaomi Nangaku
    • Journal Title

      Diabetes Metab J

      Volume: 1 Issue: 1 Pages: 11-26

    • DOI

      10.4093/dmj.2020.0217

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21J10424
  • [Journal Article] Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury2021

    • Author(s)
      Hasegawa S, Inoue T, Nakamura Y, Fukaya D, Uni R, Wu CH, Fujii R, Peerapanyasut W, Taguchi A, Kohro T, Yamada S, Katagiri M, Ko T, Nomura S, Nakanishi Ozeki A, Susaki EA, Ueda HR, Akimitsu N, Wada Y, Komuro I, Nangaku M, Inagi R.
    • Journal Title

      J Am Soc Nephrol.

      Volume: - Issue: 7 Pages: 1599-1615

    • DOI

      10.1681/asn.2020121723

    • NAID

      120007174517

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-19K22679, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21H05045
  • [Journal Article] Modulating the immune system to delay the clinical onset of type 1 diabetes.2020

    • Author(s)
      Sugahara M, Tanaka T, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 97 Issue: 2 Pages: 248-250

    • DOI

      10.1016/j.kint.2019.10.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Journal Article] Nuclear factor erythroid 2-related factor 2 as a treatment target of kidney diseases2020

    • Author(s)
      Ito Marie、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Current Opinion in Nephrology and Hypertension

      Volume: 29 Issue: 1 Pages: 128-135

    • DOI

      10.1097/mnh.0000000000000556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626
  • [Journal Article] Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration2020

    • Author(s)
      Uni Rie、Inoue Tsuyoshi、Nakamura Yasuna、Fukaya Daichi、Hasegawa Sho、Wu Chia-Hsien、Fujii Rie、Surattichaiyakul Bongkod、Peerapanyasut Wachirasek、Ozeki Atsuko、Akimitsu Nobuyoshi、Wada Youichiro、Nangaku Masaomi、Inagi Reiko
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 9472-9472

    • DOI

      10.1038/s41598-020-66295-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-19K22679
  • [Journal Article] Prolyl hydroxylase inhibition protects the kidneys from ischemia via upregulation of glycogen storage.2020

    • Author(s)
      Ito M, Tanaka T, Ishii T, Wakashima T, Fukui K, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 97 Issue: 4 Pages: 687-701

    • DOI

      10.1016/j.kint.2019.10.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
  • [Journal Article] JTZ-951, an HIF prolyl hydroxylase inhibitor, suppresses renal interstitial fibroblast transformation and expression of fibrosis-related factors.2020

    • Author(s)
      Wakashima T, Tanaka T, Fukui K, Komoda Y, Shinozaki Y, Kobayashi H, Matsuo A, Nangaku M.
    • Journal Title

      Am J Physiol Renal Physiol.

      Volume: 318 Issue: 1 Pages: F14-F24

    • DOI

      10.1152/ajprenal.00323.2019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18H02824
  • [Journal Article] Intracellular calcium response of primary cilia of tubular cells to modulated shear stress under oxidative stress2020

    • Author(s)
      Chikamori Masatomo、Kimura Hiroshi、Inagi Reiko、Zhou Jing、Nangaku Masaomi、Fujii Teruo
    • Journal Title

      Biomicrofluidics

      Volume: 14 Issue: 4 Pages: 044102-044102

    • DOI

      10.1063/5.0010737

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02727
  • [Journal Article] Effects of a prolyl hydroxylase inhibitor on kidney and cardiovascular complications in a rat model of chronic kidney disease.2020

    • Author(s)
      Uchida L, Tanaka T, Saito H, Sugahara M, Wakashima T, Fukui K, Nangaku M.
    • Journal Title

      Am J Physiol Renal Physiol.

      Volume: 318 Issue: 2 Pages: F388-F401

    • DOI

      10.1152/ajprenal.00419.2019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
  • [Journal Article] Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan2020

    • Author(s)
      Yoshida Y, Kashiwabara K, Hirakawa Y, Tanaka T, Noso S, Ikegami H, Ohsugi M, Ueki K, Mita T, Watada H, Koya D, Mise K, Wada J, Shimizu M, Wada T, Ito Y, Narita I, Kashihara N, Nangaku M, Matsuyama Y
    • Journal Title

      BMJ Open Diabetes Research & Care

      Volume: 8 Issue: 1 Pages: 1-8

    • DOI

      10.1136/bmjdrc-2019-000902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08530, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K09852, KAKENHI-PROJECT-20K08626
  • [Journal Article] Munc18-1-interacting protein 3 mitigates renal fibrosis through protection of tubular epithelial cells from apoptosis.2020

    • Author(s)
      Nasu K, Kawakami T, Shinohara A, Sakamoto T, Nangaku M.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 35 Issue: 4 Pages: 576-586

    • DOI

      10.1093/ndt/gfz177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-18H02824
  • [Journal Article] Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice2020

    • Author(s)
      Mai Sugahara、Shinji Tanaka、Tetsuhiro Tanaka、Hisako Saito、Yu Ishimoto、Takeshi Wakashima、Masatoshi Ueda、Kenji Fukui、Akira Shimizu、Reiko Inagi、Toshimasa Yamauchi、Takashi Kadowaki、Masaomi Nangaku
    • Journal Title

      Journal of the American Society of Nephrology

      Volume: 31 Issue: 3 Pages: 560-577

    • DOI

      10.1681/asn.2019060582

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17731, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
  • [Journal Article] Hypoxia-inducible factor prolyl hydroxylase inhibitor in the treatment of anemia in chronic kidney disease2020

    • Author(s)
      Kurata Y, Tanaka T, Nangaku M
    • Journal Title

      Curr Opin Nephrol Hypertens

      Volume: 29 Issue: 4 Pages: 414-422

    • DOI

      10.1097/mnh.0000000000000617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
  • [Journal Article] Regulatory roles of hypoxia-inducible, noncoding RNAs on mitochondrial dynamics during AKI2019

    • Author(s)
      Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Kidney International

      Volume: 95 Issue: 2 Pages: 252-253

    • DOI

      10.1016/j.kint.2018.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Journal Article] Hypoxia-Inducible Factor-Prolyl Hydroxylase Domain Inhibitors to Treat Anemia in Chronic Kidney Disease2019

    • Author(s)
      Sakashita Midori、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Contributions to Nephrology

      Volume: 198 Pages: 112-123

    • DOI

      10.1159/000496531

    • ISBN
      9783318064230, 9783318064247
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
  • [Journal Article] The role of oxidative stress and hypoxia in renal disease2019

    • Author(s)
      Honda Tomoko、Hirakawa Yosuke、Nangaku Masaomi
    • Journal Title

      Kidney Research and Clinical Practice

      Volume: 38 Issue: 4 Pages: 414-426

    • DOI

      10.23876/j.krcp.19.063

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Journal Article] JTZ-951 (enarodustat), a hypoxia-inducibe factor prolyl hydroxylase inhibitor, stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor2019

    • Author(s)
      Fukui Kenji、Shinozaki Yuichi、Kobayashi Hatsue、Deai Katsuya、Yoshiuchi Hiromi、Matsui Takuya、Matsuo Akira、Matsushita Mutsuyoshi、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      European Journal of Pharmacology

      Volume: 859 Pages: 172532-172532

    • DOI

      10.1016/j.ejphar.2019.172532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
  • [Journal Article] Mitochondrial damage causes inflammation via cGAS-STING signaling in acute kidney injury2019

    • Author(s)
      Hiroshi Maekawa, Tsuyoshi Inoue, haruki Ouchi, Tzu-Ming Jao, Reiko Inoue, Hiroshi Nishi, Rie Fujii, Fumiyoshi Ishidate, Tetsuhiro Tanaka, Yosuke Tanaka, Nobutaka Hirokawa, Masaomi Nangaku, Reiko Inagi
    • Journal Title

      Cell Reports

      Volume: 29 Issue: 5 Pages: 1261-1273

    • DOI

      10.1016/j.celrep.2019.09.050

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-19K21297
  • [Journal Article] Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/ reperfusion injury in the kidney.2019

    • Author(s)
      Inoue T,Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD
    • Journal Title

      Kidney International

      Volume: 95(3) Issue: 3 Pages: 563-576

    • DOI

      10.1016/j.kint.2018.09.020

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury.2019

    • Author(s)
      Hasegawa S, Susaki EA, Tanaka T, Komaba H, Wada T, Fukagawa M, Ueda HR, Nangaku M
    • Journal Title

      Kidney international

      Volume: AOP Issue: 1 Pages: 129-138

    • DOI

      10.1016/j.kint.2019.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05650, KAKENHI-PROJECT-18K08254, KAKENHI-PLANNED-17H06328, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18K19419
  • [Journal Article] Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet2019

    • Author(s)
      Saito Hisako、Tanaka Tetsuhiro、Sugahara Mai、Tanaka Shinji、Fukui Kenji、Wakashima Takeshi、Nangaku Masaomi
    • Journal Title

      Laboratory Investigation

      Volume: 99 Issue: 8 Pages: 1217-1232

    • DOI

      10.1038/s41374-019-0239-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
  • [Journal Article] A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial2019

    • Author(s)
      Akizawa Tadao、Nangaku Masaomi、Yamaguchi Takuhiro、Arai Masanobu、Koretomo Ryosuke、Matsui Atsushi、Hirakata Hideki
    • Journal Title

      American Journal of Nephrology

      Volume: 49 Issue: 2 Pages: 165-174

    • DOI

      10.1159/000496929

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824
  • [Journal Article] Regional variance in patterns of prescriptions for chronic kidney disease in Japan2019

    • Author(s)
      Inoue Reiko、Nishi Hiroshi、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 印刷中 Issue: 6 Pages: 859-864

    • DOI

      10.1007/s10157-019-01720-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18K08232
  • [Journal Article] The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease2019

    • Author(s)
      Hasegawa Sho、Tanaka Tetsuhiro、Saito Tomoyuki、Fukui Kenji、Wakashima Takeshi、Susaki Etsuo A.、Ueda Hiroki R.、Nangaku Masaomi
    • Journal Title

      Kidney International

      Volume: in press Issue: 5 Pages: 934-950

    • DOI

      10.1016/j.kint.2019.12.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PLANNED-17H06328, KAKENHI-PROJECT-19H03413
  • [Journal Article] Recent advances in renal regeneration2019

    • Author(s)
      Hasegawa Sho、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      F1000Research

      Volume: 8 Pages: 216-216

    • DOI

      10.12688/f1000research.17127.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Journal Article] Prolyl hydroxylase domain inhibitors: a new era in the management of renal anemia2019

    • Author(s)
      Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Annals of Translational Medicine

      Volume: 7 Issue: S8 Pages: S334-S334

    • DOI

      10.21037/atm.2019.09.118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
  • [Journal Article] ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis2019

    • Author(s)
      Jao Tzu-Ming、Nangaku Masaomi、Wu Chia-Hsien、Sugahara Mai、Saito Hisako、Maekawa Hiroshi、Ishimoto Yu、Aoe Mari、Inoue Tsuyoshi、Tanaka Tetsuhiro、Staels Bart、Mori Kazutoshi、Inagi Reiko
    • Journal Title

      Kidney International

      Volume: 95 Issue: 3 Pages: 577-589

    • DOI

      10.1016/j.kint.2018.09.023

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-PROJECT-17H01432
  • [Journal Article] Hypoxia-inducible factor stabilizers for treating anemia of chronic kidney disease2018

    • Author(s)
      Hasegawa Sho、Tanaka Tetsuhiro、Nangaku Masaomi
    • Journal Title

      Current Opinion in Nephrology and Hypertension

      Volume: 27 Issue: 5 Pages: 331-338

    • DOI

      10.1097/mnh.0000000000000431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824
  • [Journal Article] Palmitate deranges erythropoietin production via ATF4 activation of unfolded protein response2018

    • Author(s)
      Thitinun Anusornvongchai, Masaomi Nangaku, Tzu-Ming Jao, Chia-Hsien Wu, Yu Ishimoto, Hiroshi Maekawa, Tetsuhiro Tanaka, Akira Shimizu, Masayuki Yamamoto, Norio Suzuki, Ryoji Sassa, and Reiko Inagi
    • Journal Title

      Kidney Int.

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Journal Article] Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.2018

    • Author(s)
      Mimura I, Hirakawa Y, Kanki Y, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
    • Journal Title

      Sci Rep.

      Volume: 28 Issue: 1 Pages: 3779-3779

    • DOI

      10.1038/s41598-018-22180-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PROJECT-16K19477, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-16H06279
  • [Journal Article] Persistent expression of neutrophil gelatinase-associated lipocalin and M2 macrophage markers and chronic fibrosis after acute kidney injury2018

    • Author(s)
      Saito Hisako、Tanaka Tetsuhiro、Tanaka Shinji、Higashijima Yoshiki、Yamaguchi Junna、Sugahara Mai、Ito Marie、Uchida Lisa、Hasegawa Sho、Wakashima Takeshi、Fukui Kenji、Nangaku Masaomi
    • Journal Title

      Physiological Reports

      Volume: 6 Issue: 10 Pages: e13707-e13707

    • DOI

      10.14814/phy2.13707

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K15991, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17J07088
  • [Journal Article] Palmitate deranges erythropoietin production via ATF4 activation of unfolded protein response2018

    • Author(s)
      Thitinun Anusornvongchai, Masaomi Nangaku, Tzu-Ming Jao, Chia-Hsien Wu, Yu Ishimoto, Hiroshi Maekawa, Tetsuhiro Tanaka, Akira Shimizu, Masayuki Yamamoto, Norio Suzuki, Ryoji Sassa, and Reiko Inagi
    • Journal Title

      Kidney Int.

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Journal Article] Introduction: Kidney Disease and Cardiovascular Disease2018

    • Author(s)
      Nangaku Masaomi
    • Journal Title

      Seminars in Nephrology

      Volume: 38 Issue: 3 Pages: 207-207

    • DOI

      10.1016/j.semnephrol.2018.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Journal Article] Clinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome2018

    • Author(s)
      Fujisawa Madoka、Kato Hideki、Yoshida Yoko、Usui Tomoko、Takata Munenori、Fujimoto Mika、Wada Hideo、Uchida Yumiko、Kokame Koichi、Matsumoto Masanori、Fujimura Yoshihiro、Miyata Toshiyuki、Nangaku Masaomi
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 印刷中 Issue: 5 Pages: 1088-1099

    • DOI

      10.1007/s10157-018-1549-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07358, KAKENHI-PROJECT-17K16073, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
  • [Journal Article] Controversies of the classification of TMA and the terminology of aHUS.2018

    • Author(s)
      Kato H, Nangaku M, Okada H, Kagami S.
    • Journal Title

      Clin Exp Nephrol.

      Volume: 22 Issue: 4 Pages: 979-980

    • DOI

      10.1007/s10157-017-1524-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10144, KAKENHI-PROJECT-15K09246
  • [Journal Article] Sodium glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice2018

    • Author(s)
      Tanaka Shinji、Sugiura Yuki、Saito Hisako、Sugahara Mai、Higashijima Yoshiki、Yamaguchi Junna、Inagi Reiko、Suematsu Makoto、Nangaku Masaomi、Tanaka Tetsuhiro
    • Journal Title

      Kidney International

      Volume: 94 Issue: 5 Pages: 912-925

    • DOI

      10.1016/j.kint.2018.04.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K15991, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17J07088
  • [Journal Article] Intravital phosphorescence lifetime imaging of the renal cortex accurately measures renal hypoxia.2018

    • Author(s)
      Hirakawa Y, Mizukami K, Yoshihara T, Takahashi I, Khulan P, Honda T, Mimura I, Tanaka T, Tobita S, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 印刷中 Issue: 6 Pages: 1483-1489

    • DOI

      10.1016/j.kint.2018.01.015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K16070, KAKENHI-PROJECT-16K19477, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-17H02078, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-18H03509
  • [Journal Article] Guidelines for clinical evaluation of chronic kidney disease2018

    • Author(s)
      Kanda Eiichiro、Research Working Group for Establishing Guidelines for Clinical Evaluation of Chronic Kidney Disease、Kashihara Naoki、Matsushita Kunihiro、Usui Tomoko、Okada Hirokazu、Iseki Kunitoshi、Mikami Kenichi、Tanaka Tetsuhiro、Wada Takashi、Watada Hirotaka、Ueki Kohjiro、Nangaku Masaomi
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 22 Issue: 6 Pages: 1446-1475

    • DOI

      10.1007/s10157-018-1615-x

    • NAID

      120006557512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Journal Article] Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response2018

    • Author(s)
      Anusornvongchai Thitinun、Nangaku Masaomi、Jao Tzu-Ming、Wu Chia-Hsien、Ishimoto Yu、Maekawa Hiroshi、Tanaka Tetsuhiro、Shimizu Akira、Yamamoto Masayuki、Suzuki Norio、Sassa Ryoji、Inagi Reiko
    • Journal Title

      Kidney International

      Volume: 94 Issue: 3 Pages: 536-550

    • DOI

      10.1016/j.kint.2018.03.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
  • [Journal Article] Safety and effectiveness of long-term use of darbepoetin alfa in non-dialysis patients with chronic kidney disease: a post-marketing surveillance study in Japan2018

    • Author(s)
      Tanaka Tetsuhiro、Nangaku Masaomi、Imai Enyu、Tsubakihara Yoshiharu、Kamai Masatoshi、Wada Michihito、Asada Shinji、Akizawa Tadao
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 23 Issue: 2 Pages: 231-243

    • DOI

      10.1007/s10157-018-1632-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Journal Article] Organ-on-a-chipの潮流とin vitro腎臓モデルへの応用2017

    • Author(s)
      木村啓志、南学正臣、藤井輝夫
    • Journal Title

      腎臓内科・泌尿器科

      Volume: 5 Pages: 504-508

    • NAID

      40021219762

    • Data Source
      KAKENHI-PROJECT-16K15464
  • [Journal Article] Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner.2017

    • Author(s)
      Yamaguchi J, Tanaka T, Saito H, Nomura S, Aburatani H, Waki H, Kadowaki T, Nangaku M.
    • Journal Title

      Sci Rep.

      Volume: 26 Issue: 1 Pages: 6516-6516

    • DOI

      10.1038/s41598-017-06761-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835
  • [Journal Article] Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury.2017

    • Author(s)
      Tanaka S, Tanaka T, Kawakami T, Takano H, Sugahara M, Saito H, Higashijima Y, Yamaguchi J, Inagi R, Nangaku M.
    • Journal Title

      Kidney Int

      Volume: 印刷中 Issue: 1 Pages: 154-164

    • DOI

      10.1016/j.kint.2017.01.014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465, KAKENHI-PROJECT-17K15991, KAKENHI-PROJECT-17J07088, KAKENHI-PROJECT-15K09247
  • [Journal Article] Impact of end-stage renal disease on hospital outcomes among patients admitted to intensive care units: A retrospective matched-pair cohort study.2017

    • Author(s)
      Iwagami M, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Noiri E, Nangaku M, Doi K.
    • Journal Title

      Nephrology

      Volume: 印刷中 Issue: 8 Pages: 617-623

    • DOI

      10.1111/nep.12830

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Renal Hypoxia in CKD; Pathophysiology and Detecting Methods.2017

    • Author(s)
      Hirakawa Y, Tanaka T, Nangaku M.
    • Journal Title

      Front Physiol

      Volume: 8 Pages: 99-99

    • DOI

      10.3389/fphys.2017.00099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-17K16070, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K09247
  • [Journal Article] Renal Hypoxia in CKD; Pathophysiology and Detecting Methods2017

    • Author(s)
      Hirakawa Y, Tanaka T, Nangaku M
    • Journal Title

      Front Physiol

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Journal Article] Development of quality indicators for care of chronic kidney disease in the primary care setting using electronic health data: a RAND-modified Delphi method.2017

    • Author(s)
      Fukuma S, Shimizu S, Niihata K, Sada KE, Yanagita M, Hatta T, Nangaku M, Katafuchi R, Fujita Y, Koizumi J, Koizumi S, Kimura K, Fukuhara S, Shibagaki Y.
    • Journal Title

      Clin Exp Nephrol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.2017

    • Author(s)
      Okada A, Nangaku M, Jao TM, Maekawa H, Ishimono Y, Kawakami T, Inagi R.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 11168-11168

    • DOI

      10.1038/s41598-017-11049-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05280, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
  • [Journal Article] Atypical Hemolytic Uremic Syndrome2017

    • Author(s)
      Yoshida Y, Kato H and Nangaku M.
    • Journal Title

      Renal Replacement Therapy.

      Volume: 3 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s41100-016-0088-1

    • NAID

      40021361310

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246, KAKENHI-PROJECT-17K16073
  • [Journal Article] Previous dropout from diabetic care as a predictor of patients' willingness to use mobile applications for self-management: A cross-sectional study.2017

    • Author(s)
      Yamaguchi S, Waki K, Tomizawa N, Waki H, Nannya Y, Nangaku M, Kadowaki T, Ohe K.
    • Journal Title

      J Diabetes Investig

      Volume: 印刷中 Issue: 4 Pages: 542-549

    • DOI

      10.1111/jdi.12613

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26460858
  • [Journal Article] Ulcerative colitis with hepatitis B virus infection treated successfully by granulocyte monocyte apheresis.2017

    • Author(s)
      Saito H, Hanafusa N, Kishikawa J, Noiri E, Sunami E, Ishihara S, Watanabe T, Nangaku M.
    • Journal Title

      J Clin Apher

      Volume: 印刷中 Issue: 6 Pages: 584-586

    • DOI

      10.1002/jca.21450

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease.2017

    • Author(s)
      Sugahara M, Tanaka T, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 92 Issue: 2 Pages: 306-312

    • DOI

      10.1016/j.kint.2017.02.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-15K09247
  • [Journal Article] Epigenetic Changes in the Acute Kidney Injury-to-Chronic Kidney Disease Transition.2017

    • Author(s)
      Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
    • Journal Title

      Nephron.

      Volume: 137 Issue: 4 Pages: 256-259

    • DOI

      10.1159/000476078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
  • [Journal Article] Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.2017

    • Author(s)
      Hirakawa Y, Tanaka T, Nangaku M.
    • Journal Title

      J Diabetes Investig.

      Volume: - Issue: 3 Pages: 261-271

    • DOI

      10.1111/jdi.12624

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461215, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K09247
  • [Journal Article] Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury2017

    • Author(s)
      Tanaka S, Tanaka T, Kawakami T, Takano H, Sugahara M, Saito H, Higashijima Y, Yamaguchi J, Inagi R, Nangaku M
    • Journal Title

      Kidney Int

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Journal Article] Urinary N-acetyl-β-glucosaminidase and eGFR may identify patients to be treated with immuno-suppression at diagnosis in idiopathic membranous nephropathy.2017

    • Author(s)
      Bazzi C, Usui T, Rizza V, Casellato D, Gallieni M, Nangaku M.
    • Journal Title

      Nephrology

      Volume: 印刷中 Issue: 2 Pages: 175-182

    • DOI

      10.1111/nep.12952

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects.2017

    • Author(s)
      Akizawa T, Tsubakihara Y, Nangaku M, Endo Y, Nakajima H, Kohno T, Imai Y, Kawase N, Hara K, Lepore J, Cobitz A.
    • Journal Title

      Am J Nephrol

      Volume: 45 Issue: 2 Pages: 127-135

    • DOI

      10.1159/000454818

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia.2017

    • Author(s)
      Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
    • Journal Title

      Physiol Rep.

      Volume: 5 Issue: 8 Pages: e13203-e13203

    • DOI

      10.14814/phy2.13203

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251
  • [Journal Article] Mizoribine therapy combined with steroids and mizoribine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome.2017

    • Author(s)
      Saito T, Iwano M, Matsumoto K, Mitarai T, Yokoyama H, Yorioka N, Nishi S, Yoshimura A, Sato H, Ogahara S, Sasatomi Y, Kataoka Y, Ueda S, Koyama A, Maruyama S, Nangaku M, Imai E, Matsuo S, Tomino Y; Refractory Nephrotic Syndrome Study Group.
    • Journal Title

      Clin Exp Nephrol

      Volume: 印刷中

    • NAID

      120006373812

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Positron emission tomography in the diagnosis of cyst infections.2017

    • Author(s)
      Hasegawa S, Kato H, Hamasaki Y, Koiwa T, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 91 Issue: 3 Pages: 759-759

    • DOI

      10.1016/j.kint.2016.10.025

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney2017

    • Author(s)
      Sasaki Motohiro、Sasako Takayoshi、Kubota Naoto、Sakurai Yoshitaka、Takamoto Iseki、Kubota Tetsuya、Inagi Reiko、Seki George、Goto Moritaka、Ueki Kohjiro、Nangaku Masaomi、Jomori Takahito、Kadowaki Takashi
    • Journal Title

      Diabetes

      Volume: 66 Issue: 9 Pages: 2339-2350

    • DOI

      10.2337/db16-1602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15612, KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465, KAKENHI-PROJECT-26000012
  • [Journal Article] Selective plasma exchange can reduce auto-antibodies in patients with bullous pemphigoid without affecting factor XIII and fibrinogen.2017

    • Author(s)
      Nasu K, Hanafusa N, Nangaku M.
    • Journal Title

      J Clin Apher

      Volume: 印刷中 Issue: 6 Pages: 589-591

    • DOI

      10.1002/jca.21513

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease2017

    • Author(s)
      Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, Takeda N, Wake M, Honda K, Zhou J, Nangaku M
    • Journal Title

      Mol Cell Biol

      Volume: e-Pub Issue: 24

    • DOI

      10.1128/mcb.00337-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K08435, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
  • [Journal Article] 慢性腎臓病と新薬2017

    • Author(s)
      正路 久美, 稲城 玲子, 南学 正臣
    • Journal Title

      日本透析医会雑誌

      Volume: 32 Pages: 101-107

    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Journal Article] 慢性腎臓病と新薬2017

    • Author(s)
      正路 久美, 稲城 玲子, 南学 正臣
    • Journal Title

      日本透析医会雑誌

      Volume: 32 Pages: 101-107

    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Journal Article] Endothelial Dysfunction: The Secret Agent Driving Kidney Disease2016

    • Author(s)
      Johnson RJ, Nangaku M
    • Journal Title

      J Am Soc Nephrol

      Volume: 27 Pages: 3-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Journal Article] DialBetics: Smartphone-Based Self-Management for Type 2 Diabetes Patients on Insulin Injections.2016

    • Author(s)
      Waki K, Fujiu K, Hayashi A, Kimura S, Kobayashi H, Nangaku M, Kadowaki T, Ohe K.
    • Journal Title

      J Diabetes Sci Technol

      Volume: 10 Issue: 3 Pages: 804-805

    • DOI

      10.1177/1932296815619638

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Erythropoietin concentration in acute kidney injury is associated with insulin-like growth factor-binding protein-1.2016

    • Author(s)
      Yamashita T, Noiri E, Hamasaki Y, Matsubara T, Ishii T, Yahagi N, Nangaku M, Doi K.
    • Journal Title

      Nephrology

      Volume: 21 Issue: 8 Pages: 693-9

    • DOI

      10.1111/nep.12656

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Umbilical Cord Blood Transplantation-associated Nephrotic Syndrome Successfully Treated by Low-density Lipoprotein Apheresis.2016

    • Author(s)
      Sugawara Y, Honda K, Katagiri D, Nakamura M, Kawakami T, Nasu R, Hayashi A, Shintani Y, Tojo A, Noiri E, Kurokawa M, Fukayama M, Nangaku M.
    • Journal Title

      Intern Med

      Volume: 55 Pages: 2831-2836

    • NAID

      130005605877

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] New insights into molecular mechanisms of epigenetic regulation in kidney disease.2016

    • Author(s)
      Mimura I, Tanaka T, Nangaku M.
    • Journal Title

      Clin Exp Pharmacol Physiol

      Volume: 43 Issue: 12 Pages: 1159-1167

    • DOI

      10.1111/1440-1681.12663

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247
  • [Journal Article] Potential Survival Benefit of Polymyxin B Hemoperfusion in Septic Shock Patients on Continuous Renal Replacement Therapy: A Propensity-Matched Analysis.2016

    • Author(s)
      Iwagami M, Yasunaga H, Noiri E, Horiguchi H, Fushimi K, Matsubara T, Yahagi N, Nangaku M, Doi K.
    • Journal Title

      Blood Purif

      Volume: 42 Pages: 9-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome2016

    • Author(s)
      Miyata T, Uchida Y, Yoshida Y, Kato H, Matsumoto M, Kokame K, Fujimura Y, Nangaku M
    • Journal Title

      Int J Hematol

      Volume: 104 Issue: 2 Pages: 223-227

    • DOI

      10.1007/s12185-016-2021-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
  • [Journal Article] Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in Japan.. Clinical guides for atypical hemolytic uremic syndrome in Japan2016

    • Author(s)
      Kato H, Nangaku M, Hataya H, Sawai T, Ashida A, Fujimaru R, Hidaka Y, Kaname S, Maruyama S, Yasuda T, Yoshida Y, Ito S, Hattori M, Miyakawa Y, Fujimura Y, Okada H, Kagami S
    • Journal Title

      Clin Exp Nephrol.

      Volume: 20 Issue: 4 Pages: 536-43

    • DOI

      10.1007/s10157-016-1276-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in Japan.. Clinical guides for atypical hemolytic uremic syndrome in Japan.2016

    • Author(s)
      Kato H, Nangaku M, Hataya H, Sawai T, Ashida A, Fujimaru R, Hidaka Y, Kaname S, Maruyama S, Yasuda T, Yoshida Y, Ito S, Hattori M, Miyakawa Y, Fujimura Y, Okada H, Kagami S
    • Journal Title

      Pediatr Int.

      Volume: 58 Issue: 7 Pages: 549-55

    • DOI

      10.1111/ped.13044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] 非典型溶血性尿毒症症候群(aHUS)診療ガイド20152016

    • Author(s)
      香美祥二、岡田浩一、南学正臣、要伸也、丸山彰一、安田隆、加藤秀樹、吉田瑶子、服部元史、芦田明、幡谷浩史、日高義彦、澤井俊宏、伊藤秀一、藤丸季可、藤村吉博、宮川義隆
    • Journal Title

      日本腎臓学会誌

      Volume: 58 Pages: 62-75

    • NAID

      40020813177

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] Analysis of the V2 Vasopressin Receptor (V2R) Mutations Causing Partial Nephrogenic Diabetes Insipidus Highlights a Sustainable Signaling by a Non-peptide V2R Agonist.2016

    • Author(s)
      Makita N, Sato T, Yajima-Shoji Y, Sato J, Manaka K, Eda-Hashimoto M, Ootaki M, Matsumoto N, Nangaku M, Iiri T.
    • Journal Title

      J Biol Chem

      Volume: 291 Pages: 22460-22471

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] High serum ALP level is associated with increased risk of denosumab-related hypocalcemia in patients with bone metastases from solid tumors2016

    • Author(s)
      Kinoshita Y, Arai M, Ito N, Takashi Y, Makita N, Nangaku M, Shinoda Y, Fukumoto S.
    • Journal Title

      Endocr J

      Volume: 63 Issue: 5 Pages: 479-484

    • DOI

      10.1507/endocrj.EJ16-0003

    • NAID

      130005154205

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15K19528, KAKENHI-PROJECT-15K10388
  • [Journal Article] Association of Urinary Neutrophil Gelatinase-Associated Lipocalin With Long-Term Renal Outcomes in ICU Survivors: A Retrospective Observational Cohort Study.2016

    • Author(s)
      Isshiki R, Asada T, Sato D, Sumida M, Hamasaki Y, Inokuchi R, Matsubara T, Ishii T, Yahagi N, Nangaku M, Noiri E, Doi K.
    • Journal Title

      Shock

      Volume: 46 Issue: 1 Pages: 44-51

    • DOI

      10.1097/shk.0000000000000580

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells.2016

    • Author(s)
      Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, Aburatani H.
    • Journal Title

      Am J Nephrol

      Volume: 44 Pages: 276-285

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Rationale and study design of a randomized controlled trial to assess the effects of maintaining hemoglobin levels using darbepoetin alfa on prevention of development of end-stage kidney disease in non-diabetic CKD patients (PREDICT Trial).2016

    • Author(s)
      Imai E, Maruyama S, Nangaku M, Hirakata H, Hayashi T, Narita I, Kono H, Nakatani E, Morita S, Tsubakihara Y, Akizawa T.
    • Journal Title

      Clin Exp Nephrol

      Volume: 20 Issue: 1 Pages: 71-76

    • DOI

      10.1007/s10157-015-1133-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Complete remission of thrombotic microangiopathy after treatment with eculizumab in a patient with non-Shiga toxin-associated bacterial enteritis: A case report.2016

    • Author(s)
      Omura T, Watanabe E, Otsuka Y, Yoshida Y, Kato H, Nangaku M, Miyata T, Oda S.
    • Journal Title

      Medicine

      Volume: 95 Issue: 27 Pages: e4104-e4104

    • DOI

      10.1097/md.0000000000004104

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-16K09834, KAKENHI-PROJECT-15K09246
  • [Journal Article] 非典型溶血性尿毒症症候群2016

    • Author(s)
      藤澤 まどか、吉田 瑤子、加藤 秀樹、南学 正臣
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 65 Pages: 87-93

    • NAID

      40020720016

    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome.2016

    • Author(s)
      Miyata T, Uchida Y, Yoshida Y, Kato H, Matsumoto M, Kokame K, Fujimura Y, Nangaku M.
    • Journal Title

      Int J Hematol

      Volume: 104 Pages: 223-227

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Impact of clinical context on acute kidney injury biomarker performances: differences between neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein.2016

    • Author(s)
      Asada T, Isshiki R, Hayase N, Sumida M, Inokuchi R, Noiri E, Nangaku M, Yahagi N, Doi K.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 33077-33077

    • DOI

      10.1038/srep33077

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] The reduced expression of proximal tubular transporters in acquired Fanconi syndrome with κ light chain deposition.2016

    • Author(s)
      Tojo A, Asaba K, Kinugasa S, Ikeda Y, Shintani Y, Fukayama M, Nangaku M.
    • Journal Title

      Med Mol Morphol

      Volume: 49 Pages: 48-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Impact of continuous renal replacement therapy intensity on septic acute kidney injury.2016

    • Author(s)
      Mayumi K, Yamashita T, Hamasaki Y, Noiri E, Nangaku M, Yahagi N, Doi K.
    • Journal Title

      Shock

      Volume: 45 Issue: 2 Pages: 133-138

    • DOI

      10.1097/shk.0000000000000496

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis.2016

    • Author(s)
      Laurence J, Haller H, Mannucci PM, Nangaku M, Praga M, Rodriguez de Cordoba S.
    • Journal Title

      Clin Adv Hematol Oncol

      Volume: 14 Suppl 11 Pages: 2-15

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Interstitial renal fibrosis due to multiple cisplatin treatments is ameliorated by semicarbazide-sensitive amine oxidase inhibition.2016

    • Author(s)
      Katagiri D, Hamasaki Y, Doi K, Negishi K, Sugaya T, Nangaku M, Noiri E.
    • Journal Title

      Kidney Int

      Volume: 89 Pages: 374-85

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells.2016

    • Author(s)
      Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, Aburatani H.
    • Journal Title

      Am J Nephrol

      Volume: 44 Pages: 276-285

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Journal Article] Correction of Metabolic Alkalosis and Elevated Calcium Levels by Sodium Chloride in a Hemodialysis Patient With Inadequate Chloride Intake2016

    • Author(s)
      Hirakawa Y, Hanafusa N, Nangaku M
    • Journal Title

      Ther Apher Dial

      Volume: 20 Issue: 1 Pages: 86-7

    • DOI

      10.1111/1744-9987.12335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PLANNED-26111003
  • [Journal Article] Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments.2016

    • Author(s)
      Basile DP, Bonventre JV, Mehta R, Nangaku M, Unwin R, Rosner MH, Kellum JA, Ronco C; ADQI XIII Work Group.
    • Journal Title

      J Am Soc Nephrol

      Volume: 27 Issue: 3 Pages: 687-697

    • DOI

      10.1681/asn.2015030309

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] 非典型溶血性尿毒症症候群と遺伝子異常2016

    • Author(s)
      加藤 秀樹、吉田 瑶子、藤澤 まどか、南学 正臣
    • Journal Title

      医学のあゆみ

      Volume: 256 Pages: 1293-1294

    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] The authors reply2015

    • Author(s)
      Higashijima Y, Tanaka T, Nangaku M.
    • Journal Title

      Kidney Int.

      Volume: 87 Issue: 3 Pages: 661-661

    • DOI

      10.1038/ki.2014.410

    • Data Source
      KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-14J03553
  • [Journal Article] Therapeutic approaches targeting fibrosis and hypoxia in the kidney2015

    • Author(s)
      Tanaka T, Nangaku M.
    • Journal Title

      Nihon Jinzo Gakkai Shi.

      Volume: 57 Pages: 1215-1224

    • NAID

      40020642451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015

    • Author(s)
      Nangaku M, et. al.
    • Journal Title

      J Am Soc Nephrol.

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461207
  • [Journal Article] TMA HUSとatypical HUS2015

    • Author(s)
      南学 正臣、吉田 瑤子、加藤 秀樹
    • Journal Title

      日本内科学会雑誌

      Volume: 104 Pages: 1959-1963

    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Journal Article] Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways2015

    • Author(s)
      Kato H, Ishida J, Matsusaka T, Ishimaru T, Tanimoto K, Sugiyama F, Yagami K, Nangaku M, Fukamizu A
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0129484-e0129484

    • DOI

      10.1371/journal.pone.0129484

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26430086, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-25252062
  • [Journal Article] Aspirin and Eicosapentaenoic Acid May Arrest Progressive IgA Nephropathy: A Potential Alternative to Immunosuppression2015

    • Author(s)
      Hirahashi J, Hanafusa N, Wada T, Arita M, Hishikawa K, Hayashi M, Nangaku M
    • Journal Title

      Intern. Med.

      Volume: 54 Issue: 18 Pages: 2377-2382

    • DOI

      10.2169/internalmedicine.54.4623

    • NAID

      130005099678

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898
  • [Journal Article] Glypican-5 Increases Susceptibility to Nephrotic Damage in Diabetic Kidney.2015

    • Author(s)
      Okamoto K, Honda K, Doi K, Ishizu T, Katagiri D, Wada T, Tomita K, Ohtake T, Kaneko T, Kobayashi S, Nangaku M, Tokunaga K, Noiri E
    • Journal Title

      Am J Pathol

      Volume: 185 Issue: 7 Pages: 1989-1998

    • DOI

      10.1016/j.ajpath.2015.03.025

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09245, KAKENHI-PROJECT-15K09247
  • [Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015

    • Author(s)
      Nangaku M, Inagi R, Mimura I, Tanaka T
    • Journal Title

      J Am Soc Nephrol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Journal Article] A circulating permeability factor in focal segmental glomerulosclerosis: The hunt continues2015

    • Author(s)
      Wada T, Nangaku M
    • Journal Title

      Clinical Kidney Journal

      Volume: 8 Issue: 6 Pages: 708-15

    • DOI

      10.1093/ckj/sfv090

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Journal Article] Anti-inflammatory role of DPP-4 inhibitors in a non-diabetic model of glomerular injury2015

    • Author(s)
      Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: ahead of print Issue: 8 Pages: F878-F887

    • DOI

      10.1152/ajprenal.00590.2014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J03553, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15H04835
  • [Journal Article] Sirtuin1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes.2015

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R.
    • Journal Title

      J Am Soc Nephrol.

      Volume: 26・8 Issue: 8 Pages: 1939-59

    • DOI

      10.1681/asn.2014030289

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-15H04835
  • [Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015

    • Author(s)
      Nangaku M, Inagi R, Mimura I, Tanaka T
    • Journal Title

      J Am Soc Nephrol

      Volume: 26 Issue: 7 Pages: 1478-80

    • DOI

      10.1681/asn.2014121161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-25461207
  • [Journal Article] How the Target Hemoglobin of Renal Anemia Should Be2015

    • Author(s)
      Mimura I, Tanaka T, Nangaku M
    • Journal Title

      Nephron

      Volume: 131 Issue: 3 Pages: 202-9

    • DOI

      10.1159/000440849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627
  • [Journal Article] Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.2015

    • Author(s)
      Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.
    • Journal Title

      American Journal of Physiology Renal Physiology

      Volume: 308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Sirtuin1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes.2015

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R
    • Journal Title

      Journal of American Society of Nephrology

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Activation of hypoxia-inducible factors prevents diabetic nephropathy.2015

    • Author(s)
      8)Nordquist L, Friederich-Persson M, Fasching A, Liss P, Shoji K, Nangaku M, Hansell P, Palm F.
    • Journal Title

      J Am Soc Nephrol

      Volume: 26 Issue: 2 Pages: 328-338

    • DOI

      10.1681/asn.2013090990

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Quantitating intracellular oxygen tension in vivo by phosphorescence lifetime measurement2015

    • Author(s)
      Hirakawa Y, Yoshihara T, Kamiya M, Mimura I, Fujikura D, Masuda T, Kikuchi R, Takahashi I, Urano Y, Tobita S, Nangaku M.
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 17838-17838

    • DOI

      10.1038/srep17838

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PLANNED-15H05951, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26670425, KAKENHI-PROJECT-26860627, KAKENHI-PROJECT-26702011
  • [Journal Article] Recent advances in understanding of chronic kidney disease2015

    • Author(s)
      Yamaguchi J, Tanaka T, Nangaku M
    • Journal Title

      F1000Res

      Volume: 4 Pages: 1212-1212

    • DOI

      10.12688/f1000research.6970.1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26461215
  • [Journal Article] Role of Uremic Toxins in Erythropoiesis-Stimulating Agent Resistance in Chronic Kidney Disease and Dialysis Patients.2015

    • Author(s)
      Nangaku M, Mimura I, Yamaguchi J, Higashijima Y, Wada T, Tanaka T.
    • Journal Title

      Journal of Renal Nutrition

      Volume: 25 Issue: 2 Pages: 160-163

    • DOI

      10.1053/j.jrn.2014.10.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-14J03553, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627, KAKENHI-PROJECT-15K09247
  • [Journal Article] Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ2015

    • Author(s)
      Yamaguchi J, Tanaka T, Eto N, Nangaku M.
    • Journal Title

      Kidney International

      Volume: 印刷中 Issue: 2 Pages: 262-75

    • DOI

      10.1038/ki.2015.21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591189, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15H04835
  • [Journal Article] Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ..2015

    • Author(s)
      Yamaguchi J, Tanaka T, Eto N, Nangaku M.
    • Journal Title

      Kidney Int

      Volume: x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Journal Article] SIRT1 maintains actin cytoskeleton by deacetylation of cortactin in injured podocytes.2015

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R.
    • Journal Title

      J Am Soc Nephrol

      Volume: x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014

    • Author(s)
      Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M.
    • Journal Title

      Kidney Int Suppl

      Volume: 4 Pages: 107-112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014

    • Author(s)
      Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M.
    • Journal Title

      Kidney Int

      Volume: Suppl 4 Pages: 107-112

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Journal Article] 原発性巣状分節性糸球体硬化症の液性因子に関する最近の動向2014

    • Author(s)
      和田健彦、南学正臣
    • Journal Title

      日本腎臓学会誌

      Volume: 56 Pages: 478-85

    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Proteostasis in endoplasmic reticulum--new mechanisms in kidney disease.2014

    • Author(s)
      Inagi R, Ishimoto Y, Nangaku M.
    • Journal Title

      Nature Reviews Nephrology

      Volume: 10 Issue: 7 Pages: 369-78

    • DOI

      10.1038/nrneph.2014.67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-25461207
  • [Journal Article] ANO1: an additional key player in cyst growth.2014

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      Kidney International

      Volume: 85 Issue: 5 Pages: 1007-9

    • DOI

      10.1038/ki.2013.436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215
  • [Journal Article] A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease2014

    • Author(s)
      Wada T, Nangaku M, Maruyama S, Imai E, Shoji K, Kato S, Endo T, Muso E, Kamata K, Yokoyama H, Fujimoto K, Obata Y, Nishino T, Kato H, Uchida S, Sasatomi Y, Saito T, Matsuo S.
    • Journal Title

      Kidney Int

      Volume: 85 Issue: 3 Pages: 641-8

    • DOI

      10.1038/ki.2013.544

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-25293195, KAKENHI-PROJECT-25305028, KAKENHI-PROJECT-25461214, KAKENHI-PROJECT-25461216, KAKENHI-PROJECT-25461237, KAKENHI-PROJECT-25670408, KAKENHI-PROJECT-26305029
  • [Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014

    • Author(s)
      Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M.
    • Journal Title

      Kidney International Supplement

      Volume: 4 Pages: 107-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation.2014

    • Author(s)
      Jo-Watanabe A, Ohse T, Nishimatsu H, Takahashi M, Ikeda Y, Wada T, Shirakawa J, Nagai R, Miyata T, Nagano T, Hirata Y, Inagi R, Nangaku M.
    • Journal Title

      Aging Cell

      Volume: Epub ahead of print Issue: 3 Pages: 519-28

    • DOI

      10.1111/acel.12204

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24300260, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-24650482, KAKENHI-PROJECT-25461207
  • [Journal Article] Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.2014

    • Author(s)
      Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN.
    • Journal Title

      Kidney International

      Volume: 87 Issue: 4 Pages: 761-770

    • DOI

      10.1038/ki.2014.362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26860627
  • [Journal Article] Role of hypoxia in progressive chronic kidney disease and implications for therapy.2014

    • Author(s)
      Shoji K, Tanaka T, Nangaku M.
    • Journal Title

      Curr Opin Nephrol Hypertens

      Volume: 23 Issue: 2 Pages: 161-8

    • DOI

      10.1097/01.mnh.0000441049.98664.6c

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-25893045
  • [Journal Article] The potential for renoprotection with incretin-based drugs2014

    • Author(s)
      Tanaka T, Higashijima Y, Wada T, Nangaku M
    • Journal Title

      Kidney Int

      Volume: 86 Issue: 4 Pages: 701-711

    • DOI

      10.1038/ki.2014.236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J03553, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215
  • [Journal Article] Galacto-oligosaccharides attenuate renal injury with microbiota modification.2014

    • Author(s)
      Satoshi Unuma Furuse, Takamoto Ohse, Airi Jo-Watanabe, Akira Shigehisa, Koji Kawakami, Takahiro Matsuki, Osamu Chonan, Masaomi Nangaku
    • Journal Title

      Physiological Reports

      Volume: 2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461210
  • [Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes2014

    • Author(s)
      Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M
    • Journal Title

      Kidney Int Suppl

      Volume: 1 Pages: 107-112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Journal Article] Revolution of nephrology research by deep sequencing : ChIP-seq and RNA-seq.2014

    • Author(s)
      Mimura I, Kanki Y, Kodama T, Nangaku M.
    • Journal Title

      Kidney International

      Volume: 85 Issue: 1 Pages: 31-38

    • DOI

      10.1038/ki.2013.321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24710227, KAKENHI-PUBLICLY-25125707
  • [Journal Article] Hypoxia as a key player in the AKI-to-CKD transition.2014

    • Author(s)
      Tanaka S, Tanaka T, Nangaku M.
    • Journal Title

      Am J Phyisol Renal Physiol

      Volume: 307 Issue: 11 Pages: F1187-F1195

    • DOI

      10.1152/ajprenal.00425.2014

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24591189, KAKENHI-ORGANIZER-26111001, KAKENHI-PROJECT-26461215
  • [Journal Article] Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements.2014

    • Author(s)
      Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro JI, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, Ruan Y, Kodama T, Wada Y.
    • Journal Title

      Genome Biology

      Volume: 15 Issue: 4

    • DOI

      10.1186/gb-2014-15-4-r63

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213, KAKENHI-PUBLICLY-25118505, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25670035, KAKENHI-PROJECT-25670619, KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-26430121, KAKENHI-PROJECT-26670397, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-26860627
  • [Journal Article] 腎性貧血と腎機能低下:New findings in a moving filed2014

    • Author(s)
      平川陽亮, 稲城玲子, 南学正臣
    • Journal Title

      腎と透析

      Volume: 76 Pages: 247-251

    • Data Source
      KAKENHI-PROJECT-25461207
  • [Journal Article] TMA 疾患概念と病因分類2013

    • Author(s)
      平川陽亮、和田健彦、南学正臣
    • Journal Title

      腎と透析

      Volume: 74 Pages: 1045-9

    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Angiogenesis and hypoxia.2013

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      Nature Rev Nephrol

      Volume: 9 Issue: 4 Pages: 211-22

    • DOI

      10.1038/nrneph.2013.35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Journal Article] HIF regulation in kidney disease.2013

    • Author(s)
      Nangaku M, Rosenberger C, Heyman SN, Eckardt KU
    • Journal Title

      Clin Exp Pharmacol Physiol

      Volume: 40 Issue: 2 Pages: 148-57

    • DOI

      10.1111/1440-1681.12005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Journal Article] Endoplasmic reticulum stress signal impairs erythropoietin production:a role for ATF4.2013

    • Author(s)
      Chiang CK, Nangaku M, Tanaka T, IwawakiT, Inagi R.
    • Journal Title

      Am J Physiol Cell Physiol.

      Volume: 304(4) Issue: 4 Pages: C342-C353

    • DOI

      10.1152/ajpcell.00153.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590880, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-25461207, KAKENHI-PUBLICLY-24113702
  • [Journal Article] Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia2013

    • Author(s)
      Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M
    • Journal Title

      FASEB J

      Volume: 27 Issue: 10 Pages: 4059-4075

    • DOI

      10.1096/fj.13-231837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24390213
  • [Journal Article] Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates eytokinesis, and its expression correlates with the prognosis of renal cell earcinoma.2013

    • Author(s)
      Shoji K, Mimura I, Murayama T, Wada T, Kume H, Goto A, Ohse T, Tanaka T, Inagi R, van der Hoorn FA, Manabe I, Homma Y, Fukayama M, Sakurai T, Hasegawa T, Aburatani H, Kodama T, Nangaku M.
    • Journal Title

      American Journal of Pathology

      Volume: 182 Issue: 6 Pages: 2191-2203

    • DOI

      10.1016/j.ajpath.2013.02.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460431, KAKENHI-PROJECT-25461207
  • [Journal Article] Novel roles of complement in renal diseases and their therapeutic consequences.2013

    • Author(s)
      Wada T, Nangaku M
    • Journal Title

      Kidney International

      Volume: XX

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Journal Article] Novel roles of complement in renal diseases and their therapeutic consequences.2013

    • Author(s)
      Wada T, Nangaku M.
    • Journal Title

      Kidney Int

      Volume: 84 Issue: 3 Pages: 441-50

    • DOI

      10.1038/ki.2013.134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24591189
  • [Journal Article] Novel therapeutic strategy with hypoxia-inducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis.2013

    • Author(s)
      Mimura I, Tanaka T, Nangaku M.
    • Journal Title

      Seminars in Nephrology

      Volume: 33 Issue: 4 Pages: 375-382

    • DOI

      10.1016/j.semnephrol.2013.05.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213
  • [Journal Article] Dysregulated oxygen metabolism of the kidney by uremic toxins2012

    • Author(s)
      Chiang CK, Tanaka T, Nangaku M
    • Journal Title

      J Ren Nutr

      Volume: 22 Pages: 77-80

    • URL

      http://www.sciencedirect.com/science/article/pii/S1051227611002184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents2012

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      Exp Cell Res

      Volume: 318 Pages: 1068-73

    • URL

      http://dx.doi.org/10.1016/j.yexcr.2012.02.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.2012

    • Author(s)
      Muratsu-Ikeda S, Nangaku M, Ikeda Y,Tanaka T, Wada T, Inagi R.
    • Journal Title

      PLoS One.

      Volume: 7(7) Issue: 7 Pages: e41462-e41462

    • DOI

      10.1371/journal.pone.0041462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590880, KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24591189
  • [Journal Article] Glyoxalase I retards renal senescence2011

    • Author(s)
      Ikeda Y, Inagi R, Miyata T, Nagai R, Arai M, Miyashita M, Itokawa M, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 2810-21

    • URL

      http://dx.doi.org/10.1016/j.ajpath.2011.08.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Glyoxalase I retards renal senescence2011

    • Author(s)
      Ikeda Y, Inagi R, Miyata T, Nagai R, Arai M, Miyashita M, Itokawa M, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 2810-21

    • URL

      http://linkinghub.elsevier.com/retrieve/pii/S0002-9440(11)00840-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Epigenetic regulation for hypoxic response via HIF and histone demethylase2011

    • Author(s)
      Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M.
    • Journal Title

      J Pharmacol Sci

      Volume: 115 Pages: 453-8

    • URL

      http://dx.doi.org/10.1254/jphs.10R19FM

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] 尿細管間質障害の免疫学的機序2011

    • Author(s)
      串田夏樹・和田健彦・南学正臣
    • Journal Title

      腎と透析

      Volume: 71号

    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Glyoxalase I retards renalsenescence.2011

    • Author(s)
      Ikeda Y, Inagi R, Miyata T, Nagai R, AraiM, Miyashita M, Itokawa M, Fujita T,Nangaku M.
    • Journal Title

      Am J Pathol.

      Volume: 179(6) Issue: 6 Pages: 2810-21

    • DOI

      10.1016/j.ajpath.2011.08.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590880
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions.2011

    • Author(s)
      Nishi H, Inagi R, Kawada N, YoshizatoK, Mimura I, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol.

      Volume: 178(1) Issue: 1 Pages: 128-39

    • DOI

      10.1016/j.ajpath.2010.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590880
  • [Journal Article] Epigenetic regulation for hypoxic response via HIF and histone demethylase2011

    • Author(s)
      Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M.
    • Journal Title

      J Pharmacol Sci

      Volume: 115 Pages: 453-8

    • URL

      https://www.jstage.jst.go.jp/article/jphs/advpub/0/advpub_10R19FM/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions2011

    • Author(s)
      Nishi H, Inagi R, Kawada N, Yoshizato K, Mimura I, Fujita T, Nangaku M
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 128-39

    • URL

      http://linkinghub.elsevier.com/retrieve/pii/S0002-9440(10)00057-X

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner2011

    • Author(s)
      Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M
    • Journal Title

      Lab Invest

      Volume: 91 Issue: 11 Pages: 1564-71

    • DOI

      10.1038/labinvest.2011.114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260, KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
  • [Journal Article] Cytoglobin, a novelglobin, plays an anti-fibrotic role in the kidney2010

    • Author(s)
      Mimura I, Nangaku M, Nishi H, Inagi R, Tanaka T, Fujita T
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299 Issue: 5 Pages: F1120-F1133

    • DOI

      10.1152/ajprenal.00145.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
  • [Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2010

    • Author(s)
      Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299 Issue: 3 Pages: F568-F576

    • DOI

      10.1152/ajprenal.00659.2009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
  • [Journal Article] Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress2010

    • Author(s)
      Palm F, Nangaku M, Fasching A, Tanaka T, Nordquist L, Hansell P, Kawakami T, Nishijima F, Fujita T
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease2010

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      Curr Opin Nephrol Hypretens

      Volume: 19 Issue: 1 Pages: 43-50

    • DOI

      10.1097/mnh.0b013e3283328eed

    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] The suffocating kidney : Tubulointerstitial hypoxia in the pathogenesis of end-stage kidney disease2010

    • Author(s)
      Mimura I, Nangaku M
    • Journal Title

      Nat Rev Nephrol

      Volume: 6 Pages: 667-78

    • URL

      http://www.nature.com/nrneph/journal/v6/n11/full/nrneph.2010.124.html

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] The role of glyoxalase system in renal hypoxia2010

    • Author(s)
      Inagi R, Kumagai T, Fujita T, Nangaku M
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 49-55

    • DOI

      10.1007/978-1-4419-1241-1_6

    • ISBN
      9781441912398, 9781441912411
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
  • [Journal Article] Cytoglobin, a novel globin, plays an anti-fibrotic role in the kidney2010

    • Author(s)
      Mimura I, Nangaku M, Nishi H, Inagi R, Tanaka T, Fujita T
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model2010

    • Author(s)
      Ohtomo S, Izuhara Y, Nangaku M, Dan T, Ito S, vanYpersele de Strihou C, Miyata T
    • Journal Title

      J Obesity pii

      Pages: 136502-136502

    • URL

      http://dx.doi.org/10.1155/2010/136502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease2010

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      Curr Opin Nephrol Hypretens

      Volume: 19 Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] The suffocating kidney : Tubulointerstitial hypoxia in the pnthogenesis of end-stage kidney disease.2010

    • Author(s)
      Mimura, Nangaku
    • Journal Title

      Nat Rev Nephrol

      Volume: 6 Pages: 667-678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease.2010

    • Author(s)
      Tanaka, Nangaku
    • Journal Title

      Curr Op Nephrol Hypertens

      Volume: 19 Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2010

    • Author(s)
      Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney2009

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Nishi H, Aburatani H, Kato H, Miyata T, Fujita T, Nangaku M
    • Journal Title

      Kidney Int

      Volume: 75 Issue: 3 Pages: 268-77

    • DOI

      10.1038/ki.2008.488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Metallothionein is up-regulated by hypoxia and stabilizes HIF in the kidney2009

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Nishi H, Aburatani H, Kato H, Miyata T, Fujita T, Nangaku M
    • Journal Title

      Kidney Int

      Volume: 75 Pages: 268-277

    • URL

      http://dx.doi.org/10.1038/ki.2008.488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Glyoxalse I overexpression ameliorates renal ischemia-reperfusion injury in rats2009

    • Author(s)
      Kumagai T, Nangaku M, Kojima I, Nagai R, Ingelfinger JR, Miyata T, Fujita T, Inagi R
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Prolyl hydroxylase inhibitors to active HIF as a novel therapeutic approach against CKD2009

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      J Pharmacol Sci

      Volume: 109 Pages: 24-31

    • URL

      http://joi.jlc.jst.go.jp/JST.JSTAGE/jphs/08R09FM?from=PubMed

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Novel therapeutic approach targeting the HIF-HRE system in the kidney.2009

    • Author(s)
      Nangaku M
    • Journal Title

      Adv Exp Biol Med 645

      Pages: 81-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells2009

    • Author(s)
      Kawakami T, Inagi R, Takano H, Sato S, Ingelfinger JR, Fujita T, Nangaku M
    • Journal Title

      Nephrol Dial Transplant

      Volume: 24 Pages: 2665-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Suppression of MAP3 kinase 6 mediates anti-angiogenic and tumor-suppressive effects via VEGF repression2009

    • Author(s)
      Eto N, Miyagishi Y, Inagi R, Fujita T, Nangaku M
    • Journal Title

      Am J Pathol

      Volume: 174 Pages: 1553-63

    • URL

      http://linkinghub.elsevier.com/retrieve/pii/S0002-9440(10)61011-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Novel therapeutic approach targeting the HIF-HRE system in the kidney2009

    • Author(s)
      Nangaku M
    • Journal Title

      Adv Exp Biol Med

      Volume: 645 Pages: 81-86

    • URL

      http://dx.doi.org/10.1007/978-0-387-85998-9_13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells2009

    • Author(s)
      Kawakami T, Inagi R, Takano H, Sato S, Ingelfinger JR, Fujita T, Nangaku M
    • Journal Title

      Nephrol Dial Transplant

      Volume: 24 Issue: 9 Pages: 2665-72

    • DOI

      10.1093/ndt/gfp215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Prolyl hydroxylase inhibitors to active HIF as a novel therapeutic approachagainst CKD.2009

    • Author(s)
      Tanaka T, Nangaku M
    • Journal Title

      J Pharmacol Sci 109

      Pages: 24-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Journal Article] Mitogen-activated protein 3kinase 6 mediates angiogenic and tumorigenic effects via vascular endothelial growth factor expression2009

    • Author(s)
      Eto N, Miyagishi M Inagi R, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol

      Volume: 174 Pages: 1553-63

    • URL

      http://dx.doi.org/10.2353/ajpath.2009.080190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats2009

    • Author(s)
      Kumagai T, Nangaku M, (他5名) Inagi R
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 296 Issue: 4 Pages: F912-F921

    • DOI

      10.1152/ajprenal.90575.2008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Journal Article] Activation of the renin-angiotehsin system and chronic hypoxia of the kidney.2008

    • Author(s)
      Nangaku, Fujita
    • Journal Title

      Hypertens Res 31

      Pages: 175-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Pathophysiological role of theglyoxalase system in renal hypoxicinjury2008

    • Author(s)
      Kumagai T, Nangaku M, Inagi R
    • Journal Title

      Ann N Y Acad Sci 1126

      Pages: 265-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Hemoglobin is expressed asanti-oxidant factor by mesangial cell2008

    • Author(s)
      Nishi H, Inagi R, Kato H, Tanemoto M,Kojima I, Son D, Fujita T, Nangaku M
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 1500-1508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Fujita T : Activation of the renin-angiotensin system and chronic hypoxia of the kidney2008

    • Author(s)
      Nangaku M
    • Journal Title

      Hypertens Res 31

      Pages: 175-184

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Angiotensin-induced hypoxia the kidney: function and structural change of the renal cirulation.2008

    • Author(s)
      Nangaku, M et al.
    • Journal Title

      Adv Exp Med Biol 121

      Pages: 85-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Fujita T : HIF and renal disease2008

    • Author(s)
      Nangaku M, Inagi R, Miyata T
    • Journal Title

      Nephron Exp Nephrol 110

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Chronic hypoxiaaggravates renal injury viasuppression of Cu/Zn-SOD- a proteomic analysis2008

    • Author(s)
      Son D, Kojima I, Inagi R, Matsumoto M,Fujita T, Nangaku M
    • Journal Title

      Am J Physiol Renal Physiol 294

      Pages: 62-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] HIF and renal disease.2008

    • Author(s)
      Nangaku, et al.
    • Journal Title

      Nephron Exp Nephrol 110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Albumin suppresses vascularendothelial growth factor viaalteration of hypoxia-induciblefactor/ hypoxia-responsive element pathway2008

    • Author(s)
      Katavetin P, Inagi R, Miyata T, TanakaT, Sassa R, Ingelfinger JR, Fujita T, Nangaku M
    • Journal Title

      Biochem Biophys Res Commun 367

      Pages: 305-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] The role of chronic hypoxia in kidney disease2008

    • Author(s)
      Nangaku M, Nishi H, Miyata T
    • Journal Title

      Chin Med J 121

      Pages: 257-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Miyata T : The role of chronic hypoxia in kidney disease2008

    • Author(s)
      Nangaku M, Nishi H
    • Journal Title

      Chin Med J 121

      Pages: 257-264

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] The role of chronic hypoxia in kidney disease.2008

    • Author(s)
      Nangaku et al.
    • Journal Title

      Chin Med J 121

      Pages: 257-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Preconditioning withendoplasmic reticulum stressameliorates mesangioproliferativeglomerulonephritis2008

    • Author(s)
      Inagi R, Kumagai T, Miyata T, Fujita T,Nangaku M
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 915-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Activation of the renin-angiotensin system and chronic hypoxia of the kidney2008

    • Author(s)
      Nangaku M, Fujita T
    • Journal Title

      Hypertens Res 31

      Pages: 175-184

    • NAID

      10024359455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Hypoxia and hypoxia-inducible factorin renal disease2008

    • Author(s)
      Nangaku M, Inagi R, Miyata T, Fujita T
    • Journal Title

      Nephron Exp Nephrol 110

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Hypoxia and the HIF system in kidney disease2007

    • Author(s)
      Nangaku M, Eckardt KU
    • Journal Title

      J Mol Med 85

      Pages: 1325-1330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Erythropoietin induces hemeoxygenase-1 expression and attenuatesoxidative stress2007

    • Author(s)
      Katavetin P, Inagi R, Miyata T, SassaR, Adler S, Eto N, Kato H, Fujita T, Nangaku M
    • Journal Title

      Biochem Biophys Res Commun 359

      Pages: 928-934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia2007

    • Author(s)
      Nangaku M, et. al.
    • Journal Title

      Arterio Thromb Vasc Biol 27

      Pages: 2548-2554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Eckardt KU : Hypoxia and the HIF system in kidney disease2007

    • Author(s)
      Nangaku M
    • Journal Title

      J Mol Med 85

      Pages: 1325-1330

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] The heat is on : an expanding role for HIFs in kidney transplantation.2007

    • Author(s)
      Nangaku M.
    • Journal Title

      J Am Soc Nephrol 18

      Pages: 13-15

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] The heat is on : an expanding role for HIFs in kidney transplantation2007

    • Author(s)
      Nangaku M
    • Journal Title

      J Am Soc Nephrol 18

      Pages: 13-15

    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Angiotensin-induced hypoxia in thekidney : functional and structuralchanges of the renal circulation2007

    • Author(s)
      Nangaku M, Inagi R, Miyata T, Fujita T
    • Journal Title

      Adv Exp Med Biol 618

      Pages: 85-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Protective role of HIF-2alpha against ischemic damage andoxidative stress in the kidney2007

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Kato H,Yamashita T, Sakiyama A, Ohneda O, Takeda N, Sata M, Miyata T, Fujita T, Nangaku M
    • Journal Title

      J Am Soc Nephrol 18

      Pages: 1218-1226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Angiotensin-induced hypoxia in the kidney: functional ahd structural changes of the renal circulation.2007

    • Author(s)
      Nangaku M, et. al.
    • Journal Title

      Adv Exp Med Biol 618

      Pages: 85-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Darbepoetin protects podocytes bypreservation of the cytoskeleton andnephrin distribution2007

    • Author(s)
      Eto N, Wada T, Inagi R, Takano H, Shimizu A, Kato H, Kurihara H, KawachiH, Shankland SJ, Fujita T, Nangaku M
    • Journal Title

      Kidney Int 72

      Pages: 455-463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Receptor-independent intracellularradical scavenging activity of anangiotensin II receptor blocker2007

    • Author(s)
      Shao J, Nangaku M, Inagi R, Kato H,Miyata T, Matsusaka T, Noiri E, Fujita T
    • Journal Title

      J Hypertens 25

      Pages: 1643-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Fujita T : Receptor-independent intracellular radical scavenging activity of an angiotensin II receptor blocker2007

    • Author(s)
      Shao J, Nangaku M, Inagi R, Kato H, Miyata T, Matsusaka T, Noiri E
    • Journal Title

      J Hypertens 25

      Pages: 1643-1649

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] van Ypersele de Strihou C, Miyata T : A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia2007

    • Author(s)
      Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M
    • Journal Title

      Arterio Thromb Vasc Biol 27

      Pages: 2548-2554

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Angiotensin-induced hypoxia in the kidney:functional and structural changes of the renal circulation2007

    • Author(s)
      Nangaku M, et. al.
    • Journal Title

      Adv Exp Med Biol 618

      Pages: 85-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Establishmentof a sandwich ELISA for human megsin,a kidney-specific serine protease inhibitor2007

    • Author(s)
      Inagi R, Izuhara Y, Tominaga N, NangakuM, Kurokawa K, Miyata T
    • Journal Title

      Nephrol Dial Transplant 22

      Pages: 3311-3317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] High Glucose Blunts VEGF Response to Hypoxia via the Oxidative Stress-Regulated HIF-HRE Pathway.2006

    • Author(s)
      Katevetin P, Miyata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 1405-1413

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Hypoxia and expression of hypoxia-inducible factor in the aging kidney.2006

    • Author(s)
      Tanaka T, Kato H, Kojima I, Ohse T, Son D, Tawakaml T, Yatagawa T, Inagi R, Fujita T, Nangaku M.
    • Journal Title

      J Gerontol A Biol Sci Med Sci 16

      Pages: 795-805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Hypoxia and expression of hypoxia-inducible factor in the aging kidney2006

    • Author(s)
      Tanaka T, Kato H, Kojima I, Ohse T, Son D, Tawakami T, Yatagawa T, Inagi R, Fujita T, Nangaku M
    • Journal Title

      J Gerontol A Biol Sel Med Sel 61

      Pages: 795-805

    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Chronic hypoxia and tubulointerstitial injury. A final common pathway to end stage renal failure.2006

    • Author(s)
      Nangaku M
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 17-25

    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Chronic hypoxia and tubulointerstitial injury. A final common pathway to end stage renal failure.2006

    • Author(s)
      Nangaku M.
    • Journal Title

      Journal of American Society of Nephrology 17

      Pages: 17-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390246
  • [Journal Article] High Glucose VEGF Response to Hypoxia via the Oxidative Stress-Regulated HIF-HRE Pathway2006

    • Author(s)
      Katevetin P, Miyata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 1405-1413

    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Chronic hypoxia and tubulointerstitial injury. A final common pathway to end stage renal failure.2006

    • Author(s)
      Nangaku M.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 17-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Chronic hypoxia and tubulointerstitialinjury. A final common pathway to end stage renal failure.2006

    • Author(s)
      Nangaku M.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 17-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] High Glucose Blunts VEGF Response to Hypoxia via the Oxidative Stress-Regulated HIF-HRE Pathway.2006

    • Author(s)
      Katevetin P, Mivata T, Inagi R, Tanaka T, Sassa R, Ingelfinger JR, Fujita T, Nangaku M.
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 1405-1413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Chronic hypoxia and tubulointerstitial injury : A final common pathway to end-stage renal failure.2006

    • Author(s)
      Nangaku M.
    • Journal Title

      Journal of American Society of Nephrology 17

      Pages: 17-25

    • Data Source
      KAKENHI-PROJECT-17390246
  • [Journal Article] Novel drugs and the response to hypoxia : HIF stabilizers and prolyl hydroxylase.2006

    • Author(s)
      Nangaku M, et al.
    • Journal Title

      Recent Patent Rev Cardiovasc Drug Disc 1

      Pages: 129-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390246
  • [Journal Article] Hypoxia and expression of hypoxia-inducible factor in the aging kidney.2006

    • Author(s)
      Tanaka T, Kato H, Kojima I, Ohse T, Son D, Tawakami T, Yatagawa T, Inagi R, Fujita T, Nangaku M
    • Journal Title

      J Gerontol A Biol Sci Med Sci 61

      Pages: 795-805

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.2005

    • Author(s)
      Izuhara Y, Nangaku M, Inagi R, Tominaga N, Aizawa T, Kurokawa K, van Ypersele de Strihou C, Mivata T.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 3631-3641

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Hypoxia-inducible factor (HIF) modulates tubular cell survival in cisplatin nephrotoxicity.2005

    • Author(s)
      Tanaka T, Kojima I, Ohse T, Inagi R, Miyata T, Ingelfinger JR, Fujlta T, Nangaku M
    • Journal Title

      Am J Physiol Renal Physiol 289

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Cobalt promotes angiogenesis via hypoxia-inducible factors and protects ischemic tubulolnterstitium in the remnant kidney.2005

    • Author(s)
      Tanaka T, Kojima I, Ohse T, Ingelfinger JR, Adler S, Fujita T, Nangaku M.
    • Journal Title

      Lab Invest 85

      Pages: 1292-1307

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Hypoxia-inducible factor (HIF) modulates tubular cell survival in cisplatin nephrotoxicity.2005

    • Author(s)
      Tanaka T, Kojima I, Ohse T, Inagi R, Mivata T, Ingelfinger JR, Fujita T, Nangaku M.
    • Journal Title

      Am J Physiol Renal Physio1 289

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Induction of renoprotective gene expression by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis model.2005

    • Author(s)
      Tanaka T, Matsumoto M, Inagi R, Kojima I, Fujita T, Mivata T, Nangaku M.
    • Journal Title

      Kidney Int 68

      Pages: 2714-2725

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Induction of renoprotective gene expression by cobalt ameliorates tubulointerstitial Injury in the progressive Thy1 nephritis model.2005

    • Author(s)
      Tanaka T, Matsumoto M, Inagi R, Kojima I, Fujita T, Miyata T, Nangaku M
    • Journal Title

      Kidney Int 68

      Pages: 2714-2725

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] A biological role of HIF1 in the renal medulla.2005

    • Author(s)
      Manotham K, Tanaka T, Ohse T, Kojima I, Mivata T, Inagi R, Tanaka H, Sassa R, Fujita T, Nangaku M.
    • Journal Title

      Kidney Int 67

      Pages: 1428-1439

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.2005

    • Author(s)
      Izuhara Y, Nangaku M, Inagl R, Tominaga N, Aizawa T, Kurokawa K, van Ypersele de Strihou C, Miyata T
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 3631-3641

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Cobalt promotes angiogenesis via hypoxia-inducible factors and protects ischemic tubulointerstitium in the remnant kidney.2005

    • Author(s)
      Tanaka T, Kojima I, Ohse T, Ingelfinger JR, Adler S, Fujita T, Nangaku M
    • Journal Title

      Lab Invest 85

      Pages: 1292-1307

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] A biological role of HIF-1 In the renal medulla.2005

    • Author(s)
      Manotham K, Tanaka T, Ohse T, Kojima I, Miyata T, Inagi R, Tanaka H, Sassa R, Fujita T, Nangaku M
    • Journal Title

      Kidney Int 67

      Pages: 1428-1439

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Mechanism of tubulointerstitial injury2004

    • Author(s)
      Nangaku M
    • Journal Title

      Internal Medicine 43

      Pages: 9-17

    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Complement regulatory proteins2003

    • Author(s)
      Nangaku M
    • Journal Title

      J.American Society of Nephrology 14

      Pages: 2411-2413

    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Protective role of HIF-2 alpha against ischemic damage and oxidative stress in the kidney

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Kato H, Yamashita T, Sakiyama A, Ohbneda O, Takeda N, sata M, Miyata T, Fujita T, Nangaku M
    • Journal Title

      J Am Soc Nephro in press

    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Inagi R : Glyoxalse I overexpression ameliorates renal ischemia-reperfusion injury in rats

    • Author(s)
      Kumagai T, Nangaku M, Kojima I, Nagai R, Ingelfinger JR, Miyata T, Fujita T
    • Journal Title

      Am J Physiol Renal Physiol in press

    • Data Source
      KAKENHI-PROJECT-19390228
  • [Journal Article] Protective role of HIF-2 alpha against ischemic damage and oxidative stress in the kidney.

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Kato H, Yamatita T, Sakiyama A, Ohneda O, Takada N, Sata M, Miyata T, Fijita T, Nangaku M
    • Journal Title

      J Am Soc Nephrol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Glyoxalse I overexpressionameliorates renal ischemiareperfusioninjury in rats

    • Author(s)
      Kumagai T, Nangaku M, Kojima I, NagaiR, Ingelfinger JR, Miyata T, Fujita T, Inagi R
    • Journal Title

      Am J Physiol Renal Physiol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Mitogen-activated protein 3kinase 6 mediates angiogenic andtumorigenic effects via vascularendothelial growth factor expression

    • Author(s)
      Eto N, Miyagishi Y, Inagi R, Fujita T, Nangaku M
    • Journal Title

      Am J Pathol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Metallothionein isup-regulated by hypoxia and stabilizesHIF in the kidney

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Nishi H, Aburatani H, Kato H, Miyata T, FujitaT, Nangaku M
    • Journal Title

      Kidney Int (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Journal Article] Protective role of HIF2 alpha against ischemic damage and oxidative stress in the kidney.

    • Author(s)
      Kojima I, Tanaka T, Inagi R, Kato H, Yamashita T, Sakiyama A, Ohneda 0, Takeda N, Sata M, Miyata T, Fujita T, Nangaku M.
    • Journal Title

      J Am Soc Nephrol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209030
  • [Journal Article] Novel drugs and the response to hypoxia : HIF stabilizers and prolyl hydroxylase.

    • Author(s)
      Nangaku M et al.
    • Journal Title

      Recent Patents on Cardiovascular Drug Discovery (In press)

    • Data Source
      KAKENHI-PROJECT-17390246
  • [Presentation] Genetic knocking down of IP3R2 protects proximal tubular cells from cell cycle G1 arrest caused by AR and promotes cells survival2024

    • Author(s)
      Qi Li, Sho Hasegawa, Yuto Takenaka, Chigusa Kitayama, Kenzo Hirose, Shigeyuki Namiki, Masaomi Nangaku, Reiko Inagi
    • Organizer
      The 13th Chronic Kidney Disease Frontier Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02824
  • [Presentation] Oxygen biology in kidney disease2024

    • Author(s)
      Masaomi Nangaku
    • Organizer
      43RD ANNUAL CONFERENCE OF Indian Society of Nephrology Southern Chapter & 6th Chapter TSNCON
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] Oxygen biology in the kidney2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      56th. National Congress of Nephrology, The College of Nephrologists of Mexico A.C.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] Renal hypoxia and its relationship with kidney disease: pathophysiology and therapeutic opportunities2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      XX SLANH CONGRESS 2023/ XXIV ARGENTINE CONGRESS OF NEPHROLOGY
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] 糖尿病性腎臓病患者の尿中エイコサノイドおよび関連メディエーターの包括的分析によるrapid declinerの検出(Comprehensive analysis of eicosanoids and related mediators in diabetic kidney disease patients' urine to detect rapid decliners)2023

    • Author(s)
      Hirakawa Yosuke, Kurano Makoto, Yoshioka Kentaro, Morita Yoshifumi, Yatomi Yutaka, Nangaku Masaomi, Inagi Reiko
    • Organizer
      第66回日本腎臓学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02824
  • [Presentation] Challenges and innovations in nephrology2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Brazilian Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] HIF Stabilization: Pathophysiology and Evidence-based Medicine2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      World Congress of Nephrology 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] anemia in CKD2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      53rd Annual National Conference of Indian Society 0f Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] The New Paradigm of Anemia in CKD: From Pathogenesis to Treatment2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      The XV National Congress & Annual Meeting of Indonesian Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] マクロファージの炎症応答は小胞体-エンドソーム接触部位を介したエンドソーム成熟機構によって制御される2023

    • Author(s)
      北山智草, 長谷川頌, 南学正臣, 稲城玲子
    • Organizer
      第33回日本メイラード学会年会
    • Data Source
      KAKENHI-PROJECT-21H02824
  • [Presentation] Development of new therapies to combat kidney disease2023

    • Author(s)
      Masaomi Nangaku
    • Organizer
      60th European Renal Association Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27615
  • [Presentation] アセチルコリン受容体刺激は脾臓のマクロファージ細胞連関を惹起し抗炎症効果を発揮する2022

    • Author(s)
      中村 恭菜, 井上 剛, 呉 家賢, 南学 正臣, 稲城 玲子
    • Organizer
      日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-21K19439
  • [Presentation] アセチルコリン受容体刺激は脾臓のマクロファージ細胞連関を惹起し抗炎症効果を発揮する2022

    • Author(s)
      中村 恭菜, 井上 剛, 呉 家賢, 南学 正臣, 稲城 玲子
    • Organizer
      日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-21H02824
  • [Presentation] H3K27脱メチル化酵素阻害薬GSKJ4の腎繊維化に与える影響2021

    • Author(s)
      佐藤大、三村維真理、田中哲洋、南学正臣
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K08604
  • [Presentation] H3K27脱メチル化酵素阻害薬であるGSKJ4の腎繊維化に与える影響2021

    • Author(s)
      佐藤大、三村維真理、山崎智貴、伊藤理加、南学正臣
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08604
  • [Presentation] Renal Repair Mechanisms Post-AKI: Targets for Intervention?2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asia Pacific AKI and CRRT conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] HIF-PH inhibitor and the Nobel prize2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] New Era of Anemia Treatment2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Latest Evidence of Treatment in CKD Anemia with Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Taiwan Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] potential benefits and harms of HIF-PH inhibitor2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Chinese Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Tubular inflammation via cGAS-STING pathway is a therapeutic target for Acute Kidney Injury2020

    • Author(s)
      Hiroshi Maekawa, Masaomi Nangaku, Reiko Inagi
    • Organizer
      第63回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02727
  • [Presentation] AKI transition to CKD2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Development and clinical application of HIF-PHI in Japan2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Fudan HIF forum
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Molecular treatment strategies for AKI - a look into the crystal ball2020

    • Author(s)
      Masaomi Nangaku
    • Organizer
      European Renal Association/European Dialysis and Transplantation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Kidney disease in Japan2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Berliner DialyseSeminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] New therapies for diabetic nephropathy2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Nephrology Biennial Review Course of WCN 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Anemia in CKD/ESKD: Is it still EPO?2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asian Colloquium in Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Targeting oxidative stress and inflammation in diabetic kidney disease2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Satellite Symposium of WCN 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Oxygen metabolism in AKI and CKD2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] The Molecular Mechanisms of AKI to CKD Transition and Its Clinical Implication2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      3rd Asia Pacific AKI CRRT Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Therapy of diabetic kidney disease: current and future2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      International Cogress of Diabetes and Metabolism 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Treatment strategies targeting hypoxia and oxidative stress - HIF and Nrf22019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      International Diabetes Federation Congress 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] CKDと酸素代謝異常2019

    • Author(s)
      田中哲洋、南学正臣
    • Organizer
      第92回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] The Role of Hypoxia and HIF in Tubule Injury2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Keystone Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] New era of diabetic kidney disease2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Hong Kong Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] AKI-to-CKD transition2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Chinese Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] The Role of Hypoxia and HIF in Tubule Injury2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Keystone Symposium: Unraveling the Secrets of Kidney Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Update on anemia management in patients with CKD2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      APSN/HKSN CME course
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] HIF stabilizer in management of renal anemia2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Nephrology Biennial Review Course of WCN 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Mechanisms of AKI-on-CKD2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      2019 Asia-Pacific AKI to/on CKD Summit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Pathogenesis and treatment of CKD and its complications2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asia Pacific Chapter Meeting of the ISPD
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Oxidative stress and hypoxia as novel therapeutic targets in kidney disease2019

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Korean Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] 慢性腎不全治療薬の開発 その課題と今後への期待2018

    • Author(s)
      南学正臣
    • Organizer
      日本腎臓学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Determination of oxygen tension in normal and fibrotic kidney using phosphorescence lifetime imaging microscope.2018

    • Author(s)
      Yosuke Hirakawa, Kiichi Mizukami, Tomoko Honda, Toshitada Yoshihara, Imari Mimura, Tetsuhiro Tanaka, Seiji Tobita, Masaomi Nangaku
    • Organizer
      2018年度日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] Hes1, a Newly Identified Downstream Mediator of α7nAChR on Macrophages in the Cholinergic Anti-Inflammatory Pathway, Plays a Protective Role in AKI2018

    • Author(s)
      Inoue T, Abe C, Tanaka S, Rosin DL, Nangaku M, Wada Y, Okusa MD.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] The Molecular Machanisms of AKI to CKD Transition and Its Clinical Implication2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      2nd Asia-Pacific AKI CRRT Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] ATF6α and PPARα Cross-Talk Provides New Insights into Lipotoxicity-Induced Tubulointerstitial Fibrosis2018

    • Author(s)
      Jao T-M, Inoue T, Sugahara M, Maekawa H, Ishimoto Y, Tanaka T, Nangaku M, Inagi R.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Anti-oxidative stress therapy against DKD2018

    • Author(s)
      南学正臣
    • Organizer
      第33回日本糖尿病合併症学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Diabetic nephropathy: Is there anything new?2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Malaysian Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] The AKI to CKD Continuum: a Clinical Perspective2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Annual Meeting of the Hong Kong Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Hes1, a Newly Identified Downstream Mediator of alpha7nAChR on Macrophages in the Cholinergic Anti-Inflammatory Pathway, Plays a Protective Role in AKI2018

    • Author(s)
      Inoue T, Abe C, Tanaka S, Rosin DL, Nangaku M, Wada Y, Okusa MD.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Nrf2活性化薬の可能性2018

    • Author(s)
      南学正臣
    • Organizer
      第30回日本糖尿病性腎症研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] The AKI to CKD Continuum: a Clinical Perspective2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Hong Kong Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] New insights into AKI to CKD continuum and the role of maladaptive repair2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Anuual Meeting of the Korean Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Efficacy and Safety of Daprodustat on Anemia Management in Japanese Hemodialysis Patients Not Using Erythropoiesis-Stimulating Agents2018

    • Author(s)
      Fujii T, Tsubakihara Y, Akizawa T, Nangaku M, Onoue T, Yonekawa T, Endo Y, Cobitz AR.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] PHD inhibition reduces reactive oxidative stress in in vitro ischemia model2018

    • Author(s)
      Marie Ito, Tetsuhiro Tanaka, Masaomi Nangaku
    • Organizer
      ASN Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] AKI to CKD Transition2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Diabetic Nephropathy: What is new?2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Academic Conference of 70th Establishment Anniversary of VMMU
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Mitochondrial abnormality facilitates cyst formation in autosomal dominant polycystic kidney disease.2018

    • Author(s)
      Ishimoto Y, Nangaku M, Nishio S, Kawano H, Horie S, Kasahara T, Osafune K, Honda K, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Pathophysiological impact of elasticity, estimated by atomic force microscopy, on podocyte function.2018

    • Author(s)
      Ishimoto Y, Nangaku M, Tanaka S, Okabe S, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] PHD Inhibition Reduces Reactive Oxidative Stress in In Vitro Ischemia Model2018

    • Author(s)
      Ito M, Tanaka T, Wakashima T, Nangaku M, Fukui K.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Crosstalk between ER stress and lipid metabolism provides a new insight in lipotoxicity-induced tubulointerstitial fibrosis.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第3回生活習慣病とがんと代謝栄養メカニズム研究会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] From diabetic nephropathy to diabetic kidney disease2018

    • Author(s)
      Nangaku M.
    • Organizer
      The 16th Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] UPR deranges lipid metabolism and accelerates tubulointersitital fibrosis: ATF6-PPARa axis.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第30回腎と脂質研究会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] PHD Inhibition Reduces Reactive Oxidative Stress in In Vitro Ischemia Model2018

    • Author(s)
      Ito M, Tanaka T, Wakashima T, Nangaku M, Fukui K.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Randomized, Placebo-Controlled Phase 2 Trials of Vadadustat, an Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor (HIF-PHI), to Treat Anemia of CKD2018

    • Author(s)
      Nangaku M, Khawaja Z, Luo W, Garafola S, deGoma E, Komatsu Y.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] New insights into AKI to CKD continuum and the role of maladaptive repair2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Korean Soceity of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Randomized, Placebo-Controlled Phase 2 Trials of Vadadustat, an Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor (HIF-PHI), to Treat Anemia of CKD2018

    • Author(s)
      Nangaku M, Khawaja Z, Luo W, Garafola S, deGoma E, Komatsu Y.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] AKI to CKD Transition2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Multiple, Systemic Effects of PHD Inhibitors Signify an Anti-Fibrotic and Anti-Inflammatory Impact on Cardiovascular Complications in the Remnant Kidney2018

    • Author(s)
      Lisa Uchida, Tetsuhiro Tanaka, Hisako Saito, Mai Sugahara, Kenji Fukui, Takeshi Wakashima, Masaomi Nangaku
    • Organizer
      ASN Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] UPR deranges lipid metabolism and accelerates tubulointersitital fibrosis: ATF6-PPARa axis.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第30回腎と脂質研究会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Update of management of diabetic nephropathy2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Korean Soceity of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Mitochondrial DNA Leakage Causes Inflammation via the cGAS-STING Axis in Cisplatin-Mediated Tubular Damage2018

    • Author(s)
      Maekawa H, Jao T-M, Inoue R, Nishi H, Inoue T, Nangaku M, Inagi R.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Mitochondrial abnormality facilitates cyst formation in autosomal dominant polycystic kidney disease.2018

    • Author(s)
      Ishimoto Y, Nangaku M, Nishio S, Kawano H, Horie S, Kasahara T, Osafune K, Honda K, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] The molecular mechanisms of AKI to CKD transition and its clinical implication2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Asia Pacific AKI CRRT conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Anemia treatment in CKD: Update2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Annual Meeting of the Malaysian Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] The Burden of CKD; Challenges and Successes2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] From diabetic nephropathy to diabetic kidney disease2018

    • Author(s)
      Nangaku M.
    • Organizer
      The 16th Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Efficacy and Safety of Daprodustat on Anemia Management in Japanese Hemodialysis Patients Not Using Erythropoiesis-Stimulating Agents2018

    • Author(s)
      Fujii T, Tsubakihara Y, Akizawa T, Nangaku M, Onoue T, Yonekawa T, Endo Y, Cobitz AR.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Crosstalk between ER stress and lipid metabolism provides a new insight in lipotoxicity-induced tubulointerstitial fibrosis.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第3回生活習慣病とがんと代謝栄養メカニズム研究会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Pathophysiological impact of elasticity, estimated by atomic force microscopy, on podocyte function.2018

    • Author(s)
      Ishimoto Y, Nangaku M, Tanaka S, Okabe S, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Multiple, Systemic Effects of PHD Inhibitors Signify an Anti-Fibrotic and Anti-Inflammatory Impact on Cardiovascular Complications in the Remnant Kidney2018

    • Author(s)
      Uchida L, Tanaka T, Saito H, Sugahara M, Fukui K, Wakashima T, Nangaku M.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Can Biomarker Based Management for AKI Improve Outcomes?2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      2nd Asia-Pacific AKI CRRT Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] 糖尿病性腎臓病(DKD):新たな疾患概念:オーバービュー2018

    • Author(s)
      南学正臣
    • Organizer
      第61回日本腎臓学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Multiple, Systemic Effects of PHD Inhibitors Signify an Anti-Fibrotic and Anti-Inflammatory Impact on Cardiovascular Complications in the Remnant Kidney2018

    • Author(s)
      Uchida L, Tanaka T, Saito H, Sugahara M, Fukui K, Wakashima T, Nangaku M.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] The Burden of CKD; Challenges and Successes2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Mitochondrial DNA Leakage Causes Inflammation via the cGAS-STING Axis in Cisplatin-Mediated Tubular Damage2018

    • Author(s)
      Maekawa H, Jao T-Z, Inoue R, Nishi H, Inoue T, Nangaku M, Inagi R.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Anemia treatment in CKD: Update2018

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Malaysian Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] ATF6 Activation Drives Lipotoxicity and Tubulointerstitial Fibrosis in renal Ischemia-Reperfusion injury.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, OkadaA, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Epigenetic change in progression of AKI to CKD2018

    • Author(s)
      Nangaku M.
    • Organizer
      The 16th Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] 慢性腎臓病における心・血管障害2018

    • Author(s)
      南学正臣
    • Organizer
      日本下肢救済・足病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Whole-Kidney Three-Dimensional Imaging Reveals the Progression of Renal Sympathetic Denervation after Ischemia-Reperfusion Injury2018

    • Author(s)
      Hasegawa S, Fukagawa M, Ueda HR, Nangaku M, Tanaka T, Susaki EA, Komaba H, Wada T, Saito H, Sugahara M, Uchida L, Ito M.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] 腎性貧血とHIF2018

    • Author(s)
      南学正臣
    • Organizer
      第10回日本下肢救済・足病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] 慢性腎臓病における心・血管障害2018

    • Author(s)
      南学正臣
    • Organizer
      第10回日本下肢救済・足病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] 糖尿病性腎臓病DKDの抑制を目指して2018

    • Author(s)
      南学正臣
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] ATF6alpha and PPARalpha Cross-Talk Provides New Insights into Lipotoxicity-Induced Tubulointerstitial Fibrosis2018

    • Author(s)
      Jao T-M, Inoue T, Sugahara M, Maekawa H, Ishimoto Y, Tanaka T, Nangaku M, Inagi R.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] DETERMINATION OF OXYGEN TENSION IN TUBULAR EPITHELIAL CELLS USING PHOSPHORESCENCE LIFETIME IMAGING MICROSCOPY.2018

    • Author(s)
      Yosuke Hirakawa, Kiichi Mizukami, Toshitada Yoshihara, Tomoko Honda, Imari Mimura, Tetsuhiro Tanaka, Seiji Tobita, Masaomi Nangaku.
    • Organizer
      ERA-EDTA meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] Epigenetic change in progression of AKI to CKD2018

    • Author(s)
      Nangaku M.
    • Organizer
      The 16th Asian Pacific Congress of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 慢性腎不全治療薬の開発 その課題と今後への期待2018

    • Author(s)
      南学正臣
    • Organizer
      第61回日本腎臓学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] Mitochondrial Morphological Abnormality in Cyst Epithelial Cells of Autosomal Dominant Polycystic Kidney Disease Patients2018

    • Author(s)
      Ishimoto Y, Shimizu A, Kugita M, Nagao S, Honda K, Inagi R, Nangaku M, Nishio S, Kawano H, Horie S, Kasahara T, Osafune K, Hoshino J, Ubara Y.
    • Organizer
      American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02824
  • [Presentation] ATF6 Activation Drives Lipotoxicity and Tubulointerstitial Fibrosis in renal Ischemia-Reperfusion injury.2018

    • Author(s)
      Jao TM, Wu CH, Maekawa H, Aoe M, OkadaA, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      ISN-Frontiers Meetings 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Gene expression profiles of glomeruli from BTBR ob/ob mice treated with propel hydroxyls inhibitor suggest involvement of extracellular matrix modulators in pathogenesis of diabetic kidney disease2017

    • Author(s)
      Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Mitochondrial dysfunction contributes to cyst proliferation via oxidative stress in autosomal dominant polycystic kidney disease.2017

    • Author(s)
      Ishimoto Y, Inagi R, Nagao S, Kugita M, Shimizu A, Osafune K, Zhou J, Nangaku M.
    • Organizer
      WCN ’17 (International Society of Nephrology Meeting)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Update of anemia management in CKD patients2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 2nd International Congress of Chinese Nephrologists
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Mitochondrial dysfunction contributes to cyst proliferation via oxidative stress in autosomal dominant polycystic kidney disease.2017

    • Author(s)
      Ishimoto Y, Inagi R, Nagao S, Kugita M, Shimizu A, Osafune K, Zhou J, Nangaku M.
    • Organizer
      WCN ’17 (International Society of Nephrology Meeting)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] D-セリンはアミノ酸代謝経路を介して尿細管老化を促進させる新規尿毒素である2017

    • Author(s)
      岡田 啓、Tzu-Ming Jao、南学正臣、稲城玲子
    • Organizer
      第一回日本Uremic Toxin研究会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Epigenetics and CKD2017

    • Author(s)
      Nangaku M.
    • Organizer
      Nephrology and Transplantation Update Course of ANZSN/APSN CME
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] D-Serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation2017

    • Author(s)
      Okada A, Jao TM, Maekawa H, Ishimoto Y, Kawakami T, Nangaku M, Inagi R
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] 「非典型溶血性尿毒症症候群診療ガイド 2015」の解説と今後の課題2017

    • Author(s)
      加藤秀樹、吉田瑶子、藤澤まどか、菅原有佳、宮田敏行、南学正臣
    • Organizer
      第11回日本血栓止血学会学術標準化委員会シンポジウム
    • Place of Presentation
      野村コンファランスプラザ日本橋
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease.2017

    • Author(s)
      Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Oxygen biology in the kidney2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 2nd NTU-UTokyo Joint Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Epigenetics and AKI-CKD transition2017

    • Author(s)
      Nangaku M.
    • Organizer
      22nd International Conference on Advances in Critical Care: AKI & CRRT 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Inhibition of Prolyl Hydroxylase Domain (PHD) Reduces Glomerular Macrophage Infiltration and Improves Albuminuria in Mice with a High Fat Diet2017

    • Author(s)
      Saito H, Tanaka T, Sugahara M, Fukui K, Wakashima T, Nangaku M.
    • Organizer
      The 51st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] 低酸素と腎障害2017

    • Author(s)
      南学正臣
    • Organizer
      第6回臨床高血圧フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] 新規貧血治療薬と今後の腎性貧血治療2017

    • Author(s)
      南学正臣
    • Organizer
      第62回透析医学会学術集会・総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Inhibition of Prolyl Hydroxylase Domain (PHD) Reduces Glomerular Macrophage Infiltration and Improves Albuminuria in Mice with a High Fat Diet2017

    • Author(s)
      Saito H, Tanaka T, Sugahara M, Fukui K, Wakashima T, Nangaku M.
    • Organizer
      The 61st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Inhibition of propel hydroxyls domain (PHD) reduces glomerular macrophage infiltration and improves albuminuria in mice with a high fat diet.2017

    • Author(s)
      Saito H, Tanaka T, Sugahara M, Fukui K, Wakashima T, Nangaku M
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] 非典型溶血性尿毒症症候群(aHUS)診療ガイド2015.2017

    • Author(s)
      加藤秀樹, 吉田瑶子, 藤澤まどか,菅原有佳, 南学正臣
    • Organizer
      第47回日本腎臓学会西部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Metabolic memory and hypoxic memory: epigenetics in diabetic nephropathy2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 53rd Annual Meeting of the Australia-New Zealand Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] D-Serine, a Novel Uremic Toxin, Induces Senescence in Human Renal Tubular Cells via GCN2 Activation.2017

    • Author(s)
      Okada A, Jao TM, Maekawa H, Ishimoto Y, Kawakami T, Nangaku M, Inagi R.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] 常染色体優性多発嚢胞腎(ADPKD)の遺伝子変異がミトコンドリア異常を惹起する新規分子メカニズムの同定.2017

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、稲城玲子.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] ATF6 deranges tubular homeostasis via mitochondrial fatty acid metabolism: a role for ATF6-PPARa axis.2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Anemia in CKD2017

    • Author(s)
      Nangaku M.
    • Organizer
      ISN/SRC CME course at Vietnam Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] D-セリンは、セリン欠乏シグナルを介した尿細管老化を亢進させる尿毒素である.2017

    • Author(s)
      岡田 啓、Jao Tzu-Ming、南学正臣、稲城玲子.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] aHUSとC3腎症の検査と診断2017

    • Author(s)
      加藤秀樹, 南学正臣
    • Organizer
      第47回日本腎臓学会東部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease.2017

    • Author(s)
      Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.2017

    • Author(s)
      Okada A, Jao TM, Nangaku M, Inagi R.
    • Organizer
      The 3rd International Conference of D-amino acid Research (IDAR2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Epigenetic change induced by HIF: hypoxic memory.2017

    • Author(s)
      Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
    • Organizer
      Uppsala Kidney Oxygen Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] ATF6 Knockout Mice Revealed That ER Stress Links Lipotoxicity and Kidney Fibrosis.2017

    • Author(s)
      Jao TM, Nangaku M, Wu CH, Sugahara M, Saito S, Ishimoto Y, Maekawa H, Aoe M, Tanaka T, Inagi R.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] D-Serine, a Novel Uremic Toxin, Induces Senescence in Human Renal Tubular Cells via GCN2 Activation.2017

    • Author(s)
      Okada A, Jao TM, Maekawa H, Ishimoto Y, Kawakami T, Nangaku M, Inagi R.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Inhibition of Glycolysis attenuates ischemia-reperfusion injury via metabolic and redox changes in proximal tubular cells.2017

    • Author(s)
      Shinohara A, Kawakami T, Nangaku M
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Treatment of anemia in CKD and doping2017

    • Author(s)
      Nangaku M.
    • Organizer
      Cunio Richardson Lecture at University of Miami
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] ATF6 activation promotes renal fibrosis through exacerbation of energy metabolism by downregulating fatty acid oxidation2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R
    • Organizer
      The 6th Chronic Kidney Disease Frontier Meeting
    • Place of Presentation
      Nagoya
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] The role of HIF stabilizer in renal fibrosis2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 37th Annual Meeting of the Korean Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] D-セリンは、セリン欠乏シグナルを介した尿細管老化を亢進させる尿毒素である.2017

    • Author(s)
      岡田 啓、Jao Tzu-Ming、南学正臣、稲城玲子.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Treatment of anemia in CKD and doping2017

    • Author(s)
      Nangaku M.
    • Organizer
      Cunio Richardson Lecture at University of Miami
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] 補体系腎疾患における診断プロセスと最終診断2017

    • Author(s)
      加藤秀樹, 南学正臣.
    • Organizer
      第60回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] D-セリンは、アミノ酸欠乏シグナルを介した尿細管老化を亢進させる新規尿毒素である.2017

    • Author(s)
      岡田啓、Tzu-Ming Jao、南学正臣、稲城玲子.
    • Organizer
      第54回日本臨床分子医学会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-セリンはアミノ酸代謝経路を介して尿細管老化を促進させる新規尿毒素である2017

    • Author(s)
      岡田 啓、Tzu-Ming Jao、南学正臣、稲城玲子
    • Organizer
      第一回日本Uremic Toxin研究会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Inhibition of prolyl hydroxylase domain (PHD) reduces glomerular macrophage infiltration and improves albuminuria in mice with high fat diet2017

    • Author(s)
      Hisako Saito, Tetsuhiro Tanaka, Mai Sugahara, Kenji Fukui, Takeshi Wakashima, Masaomi Nangaku
    • Organizer
      ASN Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] Epigenetics and AKI-CKD transition.2017

    • Author(s)
      Nangaku M.
    • Organizer
      22nd International Conference on Advances in Critical Care: AKI & CRRT 2017
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2017-03-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Metabolic memory and hypoxic memory: epigenetics in diabetic nephropathy2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 53rd Annual Meeting of the Australia/New Zealand Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] ATF6 Knockout Mice Revealed That ER Stress Links Lipotoxicity and Kidney Fibrosis.2017

    • Author(s)
      Jao TM, Nangaku M, Wu CH, Sugahara M, Saito S, Ishimoto Y, Maekawa H, Aoe M, Tanaka T, Inagi R.
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] ATF6 activation drives lipotoxicity and tubulointerstitial fibrosis in mice.2017

    • Author(s)
      Jao TM, Wu CH, Maekawa H, AoeM, Okada A, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第8回腎不全研究会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Inhibition of Glycolysis Attenuates Ischemia-Reperfusion Injury via Metabolic and Redox Changes in Proximal Tubular Cells2017

    • Author(s)
      Shinohara A, Kawakami T, Nangaku M.
    • Organizer
      The 61st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] ATF6 activation promotes renal fibrosis through exacerbation of energy metabolism by downregulating fatty acid oxidation2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R
    • Organizer
      The 6th Chronic Kidney Disease Frontier Meeting
    • Place of Presentation
      Nagoya
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Update of anemia management in CKD patients2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 2nd International Congress of Chinese Nephrologists
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] PHD阻害薬は2型糖尿病マウスのアルブミン尿を減少させ、糖と脂質代謝を改善する.2017

    • Author(s)
      菅原真衣、田中真司、齊藤久さこ、福井健人、石本 遊、稲城玲子、南学正臣、田中哲洋.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease2017

    • Author(s)
      Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
    • Organizer
      The 51st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Inhibition of Glycolysis Attenuates Ischemia-Reperfusion Injury via Metabolic and Redox Changes in Proximal Tubular Cells2017

    • Author(s)
      Shinohara A, Kawakami T, Nangaku M.
    • Organizer
      The 51st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] ATF6 exacerbates lipid deposition-associated tubulointerstitial fibrosis via downregulation of PPAR-mediated fatty acid metabolism2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R
    • Organizer
      第29回腎と脂質研究会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] ATF6 knockout mice revealed that ER stress links lipotoxicity and kidney fibrosis.2017

    • Author(s)
      Jao TM, Wu CH, Sugahara M, Saito H, Ishimoto Y, Okada A, Maekawa H, Aoe M, Tanaka T, Nangaku M, Inagi R
    • Organizer
      Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Epigenetic change induced by HIF: hypoxic memory.2017

    • Author(s)
      Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
    • Organizer
      Uppsala Kidney Oxygen Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-serine accelerates chronic kidney disease progression via increase in tubular senescence associated with oxidative and ER stress.2017

    • Author(s)
      Okada A, Jao TM, Nangaku M, Inagi R.
    • Organizer
      WCN ’17 (International Society of Nephrology Meeting)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] ATF6 activation drives lipotoxicity and tubulointerstitial fibrosis in mice.2017

    • Author(s)
      Jao TM, Wu CH, Maekawa H, AoeM, Okada A, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      第8回腎不全研究会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-セリンは、アミノ酸欠乏シグナルを介した尿細管老化を亢進させる新規尿毒素である.2017

    • Author(s)
      岡田啓、Tzu-Ming Jao、南学正臣、稲城玲子.
    • Organizer
      第54回日本臨床分子医学会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] ATF6 deranges tubular homeostasis via mitochondrial fatty acid metabolism: a role for ATF6-PPARa axis.2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Inhibition of Glycolysis Attenuates Ischemia-Reperfusion Injury via Metabolic and Redox Changes in Proximal Tubular Cells2017

    • Author(s)
      Akinari Shinohara, Takahisa Kawakami, Masaomi Nangaku
    • Organizer
      Kidney Week 2017, American Society of Nephrology
    • Data Source
      KAKENHI-PROJECT-16K09605
  • [Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/obMice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease2017

    • Author(s)
      Mai Sugahara, Shinji Tanaka, Tetsuhiro Tanaka, Kenji Fukui, Akira Shimizu, Yu Ishimoto, Reiko Inagi, Masaomi Nangaku
    • Organizer
      ASN Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688
  • [Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease2017

    • Author(s)
      Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M
    • Organizer
      The 61st Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.2017

    • Author(s)
      Okada A, Jao TM, Nangaku M, Inagi R.
    • Organizer
      The 3rd International Conference of D-amino acid Research (IDAR2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] The role of HIF stabilizer in renal fibrosis2017

    • Author(s)
      Nangaku M.
    • Organizer
      The 37th Annual Meeting of the Korean Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] ATF6 exacerbates lipid deposition-associated tubulointerstitial fibrosis via downregulation of PPAR-mediated fatty acid metabolism2017

    • Author(s)
      Jao TM, Ishimoto Y, Okada A, Maekawa H, Nangaku M, Inagi R
    • Organizer
      第29回腎と脂質研究会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] PHD阻害薬は2型糖尿病マウスのアルブミン尿を減少させ、糖と脂質代謝を改善する.2017

    • Author(s)
      菅原真衣、田中真司、齊藤久さこ、福井健人、石本 遊、稲城玲子、南学正臣、田中哲洋.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] D-serine accelerates chronic kidney disease progression via increase in tubular senescence associated with oxidative and ER stress.2017

    • Author(s)
      Okada A, Jao TM, Nangaku M, Inagi R.
    • Organizer
      WCN ’17 (International Society of Nephrology Meeting)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] 常染色体優性多発嚢胞腎(ADPKD)の遺伝子変異がミトコンドリア異常を惹起する新規分子メカニズムの同定.2017

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、稲城玲子.
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Anemia in CKD2017

    • Author(s)
      Nangaku M.
    • Organizer
      Vietnam Society of Nephrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 当施設における非典型溶血性尿毒症症候群(aHUS)の解析2016

    • Author(s)
      藤澤 まどか、加藤 秀樹、吉田 瑤子、碓井 知子、内田 裕美子、宮田 敏行、南学 正臣
    • Organizer
      第59回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Hypoxia and persistent inflammation in CKD.2016

    • Author(s)
      Nangaku M.
    • Organizer
      XVIII International Congress on Nutrition and Metabolism in Renal Disease
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2016-04-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、清水章、Jing Zhou、稲城玲子
    • Organizer
      第7回腎不全研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Lecture: Hypoxia-Inducible Factors in Diabetic Nephropathy2016

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      McCormick Place(米国・シカゴ)
    • Year and Date
      2016-11-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] 非典型溶血性尿毒症症候群患者におけるプラスミノーゲン A620T変異2016

    • Author(s)
      宮田敏行、内田裕美子、藤村吉博、吉田瑤子、加藤秀樹、南学正臣
    • Organizer
      第38回血栓止血学会
    • Place of Presentation
      奈良春日野国際フォーラム(奈良県橿原市)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Epigenetics of renal disease.2016

    • Author(s)
      Nangaku M.
    • Organizer
      15th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Perth, Australia
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、清水 章、Jing Zhou、Mike Murphy、稲城玲子
    • Organizer
      第7回分子腎臓フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] 低酸素における炎症とepigenome.2016

    • Author(s)
      南学正臣
    • Organizer
      第16回日本抗加齢医学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、清水章、Jing Zhou、稲城玲子
    • Organizer
      第7回腎不全研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Mitochondrial dysfunction contributes to cyst proliferation of autosomal dominant polycystic kidney disease2016

    • Author(s)
      Ishimoto Y, Nangaku M, Kugita M, Nagao S, Shimizu A, Zhou J, Inagi R.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Prolyl hydroxylase inhibitor decreases albuminuria and improves glucose and lipid metabolism in a mouse model of type 2 diabetes2016

    • Author(s)
      Tanaka S, Tanaka T, Sugahara M, Saito H, Inagi R, Nangaku M.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] ミトコンドリア機能阻害は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、稲城玲子
    • Organizer
      第59回日本腎臓学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-Serine, a novel emerging uremic toxin candidate, induces cell cycle arrest and apoptosis through up-regulation of ER stress and oxidative stress in proximal tubular cells2016

    • Author(s)
      Okada A, Jao TM, Maekawa H, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Development of novel drugs targeting renal hypoxia and anaemia2016

    • Author(s)
      Nangaku M.
    • Organizer
      53rd European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2016-05-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Novel therapeutic targets in PKD, DKD, and CKD: mitochondria, ER, and oxygen metabolism.2016

    • Author(s)
      Nangaku M.
    • Organizer
      Yale Unviersity Nephrology Seminar
    • Place of Presentation
      New Haven, USA
    • Year and Date
      2016-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Oxygen biology in the kidney.2016

    • Author(s)
      Nangaku M.
    • Organizer
      2nd NTU-UTokyo Joint Conference.
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2016-12-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Development of novel drugs targeting renal hypoxia and anaemia.2016

    • Author(s)
      Nangaku M.
    • Organizer
      53rd European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2016-05-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] D-Serine, a Novel Emerging Uremic Toxin Candidate, Induces Cell Cycle Arrest and Apoptosis Through Up-Regulation of ER Stress and Oxidative Stress in Proximal Tubular Cells2016

    • Author(s)
      Akira Okada, Tzu-Ming Jao, Hiroshi Maekawa, Yu Ishimoto, Masaomi Nangaku, Reiko Inagi
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      McCormick Place(米国・シカゴ)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Analysis of genetic background and evaluation with hemolysis assay in patients with atypical hemolytic uremic syndrome in Japan2016

    • Author(s)
      Masaomi Nangaku, Hideki Kato, Yoko Yoshida, Madoka Fujisawa, Yuka Sugawara, Toshiyuki Miyata, Yumiko Uchida, Masanori Matsumoto, Yoshihiro Fujimura
    • Organizer
      Asian Pacific Congress of Nephrology (APCN)
    • Place of Presentation
      Perth
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] D―セリンは小胞体ストレスと酸化ストレスを介した尿細管老化を促進する2016

    • Author(s)
      岡田 啓、Jao Tzu-Ming、南学正臣、稲城玲子
    • Organizer
      第11回臨床ストレス応答学会
    • Place of Presentation
      山口
    • Year and Date
      2016-11-11
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] atypical HUSの診断と治療のupdate2016

    • Author(s)
      加藤秀樹、吉田瑶子、藤澤まどか、菅原有佳、南学正臣
    • Organizer
      第37回日本アフェレシス学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] Mitochondrial dysfunction contributes to cyst proliferation of autosomal dominant polycystic kidney disease2016

    • Author(s)
      Ishimoto Y, Nangaku M, Kugita M, Nagao S, Shimizu A, Zhou J, Inagi R.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D―セリンは小胞体ストレスと酸化ストレスを介した尿細管老化を促進する2016

    • Author(s)
      岡田 啓、Jao Tzu-Ming、南学正臣、稲城玲子
    • Organizer
      第11回臨床ストレス応答学会
    • Place of Presentation
      山口
    • Year and Date
      2016-11-11
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] Epigenetics of Renal Disease.2016

    • Author(s)
      Nangaku M.
    • Organizer
      15th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Perth, Australia
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Epigenetics of Renal Disease2016

    • Author(s)
      Nangaku M.
    • Organizer
      15th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Perth, Australia
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] D-Serine accelerates chronic kidney disease progression via increase in tubular senescence associated with oxidative and ER stress2016

    • Author(s)
      Okada A, Jao TM, Ishimoto Y, Maekawa H, Nangaku M, Inagi R
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] D-Serine, a novel emerging uremic toxin candidate, induces cell cycle arrest and apoptosis through up-regulation of ER stress and oxidative stress in proximal tubular cells2016

    • Author(s)
      Okada A, Jao TM, Maekawa H, Ishimoto Y, Nangaku M, Inagi R.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] D-Serine accelerates chronic kidney disease progression via increase in tubular senescence associated with oxidative and ER stress2016

    • Author(s)
      Akira Okada, Tzu-Ming Jao, Yu Ishimoto, Hiroshi Maekawa, Masaomi Nangaku and Reiko Inagi
    • Organizer
      The 39th annual meeting of the molecular biology society of Japan
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K09604
  • [Presentation] Sodium-Glucose Cotransporter 2 Inhibition Partly Phenocopies Calorie Restriction in Kidneys of a Type 2 Diabetes Mouse Model2016

    • Author(s)
      Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Masaomi Nangaku
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      McCormick Place(米国・シカゴ)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Hypoxia and persistent inflammation in CKD.2016

    • Author(s)
      Nangaku M.
    • Organizer
      XVIII International Congress on Nutrition and Metabolism in Renal Disease
    • Place of Presentation
      Okinawa,, Japan
    • Year and Date
      2016-04-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] D-Serine, a novel emerging uremic toxin candidate, induces cell cycle arrest and apoptosis through up-regulation of er stress and oxidative stress in proximal tubular cells2016

    • Author(s)
      Akira Okada, Tzu-Ming Jao, Hiroshi Maekawa, Yu Ishimoto, Masaomi Nangaku and Reiko Inagi
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09604
  • [Presentation] Characterization of the patients with atypical hemolytic uremic syndrome by combination of hemolytic assay and gene analysis in Japan2016

    • Author(s)
      Yoko Yoshida, Hideki Kato, Madoka Fujisawa, Yuuka Sugahara, Yumiko Uchida, Masanori Matsumoto, Yoshihiro Fujimura, Toshiyuki Miyata, Nangaku Masaomi
    • Organizer
      26th INTERNATIONAL COMPLEMENT WORKSHOP
    • Place of Presentation
      金沢
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、釘田雅則、長尾静子、清水 章、Jing Zhou、Mike Murphy、稲城玲子
    • Organizer
      第7回分子腎臓フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] VAP-1酵素活性の阻害は、好中球浸潤の抑制を介して腎虚血再灌流障害を軽減する2016

    • Author(s)
      田中真司、田中哲洋、稲城玲子、南学正臣
    • Organizer
      第59回日本腎臓学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-16K15465
  • [Presentation] ミトコンドリア機能阻害は多発性嚢胞腎の嚢胞形成に関与する2016

    • Author(s)
      石本 遊、南学正臣、稲城玲子
    • Organizer
      第59回日本腎臓学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Anemia management update.2016

    • Author(s)
      Nangaku M.
    • Organizer
      15th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Perth, Australia
    • Year and Date
      2016-09-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Hypoxia-Inducible Factors in Diabetic Nephropathy.2016

    • Author(s)
      Nangaku M.
    • Organizer
      50th American Society of Nephrology
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-11-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Vascular Adhesion Protein-1 Promotes Neutrophil Infiltration via Hydrogen Peroxide Generation in Renal Ischemia-Reperfusion Injury2016

    • Author(s)
      Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Reiko Inagi, Masaomi Nangaku
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      McCormick Place(米国・シカゴ)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Epigenetics of Renal Disease2016

    • Author(s)
      Nangaku M.
    • Organizer
      15th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Perth, Australia
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 非典型溶血性尿毒症症候群(aHUS)の現状と今後2016

    • Author(s)
      加藤 秀樹, 吉田 瑶子, 藤澤 まどか, 菅原 有佳, 南学 正臣
    • Organizer
      第46回日本腎臓学会東部学術大会
    • Place of Presentation
      京王プラザホテル、東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] D-Serine accelerates chronic kidney disease progression via increase in tubular senescence associated with oxidative and ER stress2016

    • Author(s)
      Okada A, Jao TM, Ishimoto Y, Maekawa H, Nangaku M, Inagi R
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Oxygen biology in the kidney.2016

    • Author(s)
      Nangaku M.
    • Organizer
      2nd NTU-UTokyo Joint Conference
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2016-12-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] VAP-1酵素活性の阻害は、好中球浸潤の抑制を介して腎虚血再灌流障害を軽減する2016

    • Author(s)
      田中真司、田中哲洋、稲城玲子、南学正臣
    • Organizer
      第59回日本腎臓学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Hypoxia-inducible factors in diabetic nephropathy.2016

    • Author(s)
      Nangaku M.
    • Organizer
      50th American Society of Nephrology
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-11-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Prolyl hydroxylase inhibitor decreases albuminuria and improves glucose and lipid metabolism in a mouse model of type 2 diabetes2016

    • Author(s)
      Tanaka S, Tanaka T, Sugahara M, Saito H, Inagi R, Nangaku M.
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0088
  • [Presentation] Abnormal oxygen metabolism in the kidney.2016

    • Author(s)
      Nangaku M.
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Development of novel drugs targeting renal hypoxia and anaemia.2016

    • Author(s)
      Nangaku M.
    • Organizer
      53rd ERA/EDTA congress
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2016-05-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Prolyl Hydroxylase Inhibitor Decreases Albuminuria and Improves Glucose and Lipid Metabolism in a Mouse Model of Type 2 Diabetes2016

    • Author(s)
      Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Kenji Fukui, Yu Ishimoto, MD, Reiko Inagi, Masaomi Nangaku
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      McCormick Place(米国・シカゴ)
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Novel therapeutic targets in PKD, DKD, and CKD: mitochondria, ER, and oxygen metabolism.2016

    • Author(s)
      Nangaku M.
    • Organizer
      Yale University Nephrology Seminar
    • Place of Presentation
      New Haven, USA
    • Year and Date
      2016-11-21
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] りん光寿命測定を用いた腎臓尿細管細胞内分圧の測定2015

    • Author(s)
      平川陽亮、吉原利忠、神谷真子、三村維真理、田中真司、田中哲洋、浦野泰照、飛田成史、南学正臣
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Hypoxia and Renal Disease.2015

    • Author(s)
      Masaomi Nangaku
    • Organizer
      8th World Congress of Nephrology
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2015-03-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] 腎性貧血とHIF2015

    • Author(s)
      南学正臣
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-06-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Hypoxia as a new therapeutic target in CKD.2015

    • Author(s)
      南学正臣
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-06
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Palmitate Exacerbates Renal Anemia: Suppression of Renal Erythropoietin Production via Endoplasmic Reticulum Stress.2015

    • Author(s)
      Reiko Inagi, Thitinun Anusornvongchai, Yu Ishimoto, Akira Okada, Norio Suzuki, Masayuki Yamamoto, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Oxidative Stres and Kidney Injury.2015

    • Author(s)
      Nangaku M.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670425
  • [Presentation] 日本人の非典型溶血性尿毒症症候群患者41人の遺伝子解析2015

    • Author(s)
      宮田敏行、内田裕美子、吉田瑶子、池島裕子、Fan Xinping、芦田明、和田英夫、大塚泰史、 中村健治、石川智朗、八田和大、服部元史、久野正貴、才田謙、西尾健治、瀧本智仁、 幡谷浩史、大原敦子、川村尚久、波多江健、松本雅則、加藤秀樹、南学正臣、藤村吉博
    • Organizer
      日本補体学会学術集会
    • Place of Presentation
      名古屋大学医学部附属病院(愛知県名古屋市)
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-15K09246
  • [Presentation] AKI-to-CKD: epidemiology and pathogenesis.2015

    • Author(s)
      Nangaku M.
    • Organizer
      Shanghai International AKI-CRRT Forum
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2015-07-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 腎不全に至る共通経路と高血圧の役割2015

    • Author(s)
      南学正臣
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県松山市)
    • Year and Date
      2015-10-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] りん光寿命測定を用いた腎臓尿細管細胞内分圧の測定2015

    • Author(s)
      平川陽亮、吉原利忠、神谷真子、三村維真理、田中真司、田中哲洋、浦野泰照、飛田成史、南学正臣
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Development of novel drugs targeting CKD: hypoxia, oxidative stress, and epigenetics.2015

    • Author(s)
      Nangaku M.
    • Organizer
      52nd European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      London, UK
    • Year and Date
      2015-05-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Inhibition of Vascular Adhesion Protein-1 Suppresses Neutrophil Infiltration and Preserves Renal Function in the Rat Model of Renal Ischemia–Reperfusion Injury.2015

    • Author(s)
      Shinji Tanaka, Tetsuhiro Tanaka, Reiko Inagi, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] 腎性貧血とHIF2015

    • Author(s)
      南学正臣
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      パシフィコ横浜国際会議場(神奈川県横浜市)
    • Year and Date
      2015-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement.2015

    • Author(s)
      Hirakawa Y, Mimura I, Yoshihara T, Kamiya M, Tanaka S, Tanaka T, Inagi R, Urano Y, Tobita S, Nangaku M.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      ウエスティン都ホテル京都(京都府京都市)
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670425
  • [Presentation] Inhibition of collagen cross-linking by lysyl oxidase prevents hypertrophy and protects from diabetic nephropathy.2015

    • Author(s)
      Tetsuhiro Tanaka, Shinji Tanaka, Hisako Saito, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku.
    • Organizer
      ERA-EDTA 52nd meeting
    • Place of Presentation
      London, UK
    • Year and Date
      2015-05-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Presentation] Quantitating Intracellular Oxygen Tension in Kidney by Phosphorescence Lifetime Measurement.2015

    • Author(s)
      Yosuke Hirakawa, Imari Mimura, Toshitada Yoshihara, Mako Kamiya, Yasuteru Urano, Seiji Tobita, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Sodium-glucose cotransporter 2 inhibition ameliorates glomerular hyperfiltration without affecting renal/glomerular hypertrophy in a mouse model of type 2 diabetes.2015

    • Author(s)
      Tanaka S, Tanaka T, Inagi R, Nangaku M.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      ウエスティン都ホテル京都(京都府京都市)
    • Year and Date
      2015-10-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Palmitate suppresses EPO production via ER stress in renal EPO producing cells.2015

    • Author(s)
      Anusomvongchai T, Tanaka S, Hirakawa Y, Suzuki n, Yamamoto M, Nangaku M, Inagi R.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      ウエスティン都ホテル京都(京都府京都市)
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Inhibition of Vascular Adhesion Protein-1 Suppresses Neutrophil Infiltration and Preserves Renal Function in the Rat Model of Renal Ischemia–Reperfusion Injury2015

    • Author(s)
      Shinji Tanaka, Tetsuhiro Tanaka, Reiko Inagi, Masaomi Nangaku,
    • Organizer
      Kidney Week 2015
    • Place of Presentation
      San Diego Convention Center, San Diego, CA, USA
    • Year and Date
      2015-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Palmitate suppresses EPO production via ER stress in renal EPO producing cells.2015

    • Author(s)
      Anusomvongchai T, Tanaka S, Hirakawa Y, Suzuki n, Yamamoto M, Nangaku M, Inagi R.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 低酸素とTGF-βは、下流にある IGFBP3 を介して、尿細管上皮細胞に apoptosis を誘導する.2015

    • Author(s)
      串田夏樹、野村征太郎、藤田隆教、三村維真理、南学正臣、油谷浩幸.
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Quantitating Intracellular Oxygen Tension in Kidney by Phosphorescence Lifetime Measurement.2015

    • Author(s)
      Yosuke Hirakawa, Imari Mimura, Toshitada Yoshihara, Mako Kamiya, Yasuteru Urano, Seiji Tobita, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670425
  • [Presentation] 低酸素とTGF-βは、下流にある IGFBP3 を介して、尿細管上皮細胞に apoptosis を誘導する.2015

    • Author(s)
      串田夏樹、野村征太郎、藤田隆教、三村維真理、南学正臣、油谷浩幸
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 腎不全に至る共通経路と高血圧の役割2015

    • Author(s)
      南学正臣
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県松山市)
    • Year and Date
      2015-10-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Hypoxia as a new therapeutic target in CKD2015

    • Author(s)
      南学正臣
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Palmitate Exacerbates Renal Anemia: Suppression of Renal Erythropoietin Production via Endoplasmic Reticulum Stress.2015

    • Author(s)
      Reiko Inagi, Thitinun Anusornvongchai, Yu Ishimoto, Akira Okada, Norio Suzuki, Masayuki Yamamoto, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Quantitating Intracellular Oxygen Tension in Kidney by Phosphorescence Lifetime Measurement.2015

    • Author(s)
      Yosuke Hirakawa, Imari Mimura, Toshitada Yoshihara, Mako Kamiya, Yasuteru Urano, Seiji Tobita, Masaomi Nangaku.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] 臍帯血移植御に認めた巣状糸球体硬化症に対しLDLアフェレシスが奏功した一例2015

    • Author(s)
      菅原有佳、亀井亮佑、本田謙次郎、伊藤麻里江、鈴木淳司、片桐大輔、林玲匡、新谷祐加子、中村元信、川上貴久、和田健彦、藤乗嗣泰、南学正臣
    • Organizer
      第45回日本腎臓学会東部学術大会
    • Place of Presentation
      東京ミッドタウンホール&カンファレンス(東京都港区)
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Hypoxia and Renal Disease2015

    • Author(s)
      Nangaku M
    • Organizer
      第8回国際腎臓学会
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2015-03-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement.2015

    • Author(s)
      Hirakawa Y, Mimura I, Yoshihara T, Kamiya M, Tanaka S, Tanaka T, Inagi R, Urano Y, Tobita S, Nangaku M.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Palmitate Exacerbates Renal Anemia: Suppression of Renal Erythropoietin Production via Endoplasmic Reticulum Stress2015

    • Author(s)
      Reiko Inagi, Thitinun Anusornvongchai, Yu Ishimoto, Akira Okada, Norio Suzuki, Masayuki Yamamoto, Masaomi Nangaku
    • Organizer
      Kidney Week 2015
    • Place of Presentation
      San Diego Convention Center, San Diego, CA, USA
    • Year and Date
      2015-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Quantitating Intracellular Oxygen Tension in Kidney by Phosphorescence Lifetime Measurement2015

    • Author(s)
      Yosuke Hirakawa, Imari Mimura, Toshitada Yoshihara, Mako Kamiya, Yasuteru Urano, Seiji Tobita, Masaomi Nangaku
    • Organizer
      Kidney Week 2015
    • Place of Presentation
      San Diego Convention Center, San Diego, CA, USA
    • Year and Date
      2015-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Oxidative Stress and Kidney Injury2015

    • Author(s)
      Masaomi Nangaku
    • Organizer
      Kidney Week 2015
    • Place of Presentation
      San Diego Convention Center, San Diego, CA, USA
    • Year and Date
      2015-11-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09247
  • [Presentation] Oxidative Stres and Kidney Injury.2015

    • Author(s)
      Nangaku M.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Development of novel drugs targeting CKD: hypoxia, oxidative stress, and epigenetics2015

    • Author(s)
      Nangaku M.
    • Organizer
      52nd European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      London, UK
    • Year and Date
      2015-05-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Oxidative Stres and Kidney Injury.2015

    • Author(s)
      Nangaku M.
    • Organizer
      The 49th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement.2015

    • Author(s)
      Hirakawa Y, Mimura I, Yoshihara T, Kamiya M, Tanaka S, Tanaka T, Inagi R, Urano Y, Tobita S, Nangaku M.
    • Organizer
      Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
    • Place of Presentation
      ウエスティン都ホテル京都(京都府京都市)
    • Year and Date
      2015-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] AKI-to-CKD: epidemiology and pathogenesis2015

    • Author(s)
      Nangaku M.
    • Organizer
      Shanghai International AKI-CRRT Forum
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2015-07-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04835
  • [Presentation] Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways.2014

    • Author(s)
      Hideki Kato, Taiji Matsusaka, Masaomi Nangaku.
    • Organizer
      The 47th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-13
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] ガラクトオリゴ糖は腸内細菌叢を変化させ,腎組織障害を改善する2014

    • Author(s)
      鵜沼智、大瀬貴元、城愛理、重久晃、川上幸治、松木隆広、長南治、南学正臣
    • Organizer
      第59回日本透析医学会
    • Place of Presentation
      神戸
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-25461210
  • [Presentation] Epigenetic Induction of Kidney Lineages in Human Kidney Derived iPS Cells.2014

    • Author(s)
      Osamu Takase, Masaomi Nangaku, Keiichi Hishikawa.
    • Organizer
      The 47th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-13
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Hypoxic HIF, Fibrosis, and CKD.2014

    • Author(s)
      Masaomi Nangaku
    • Organizer
      The 47th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Histone modifications in kidney disease2014

    • Author(s)
      Masaomi Nangaku
    • Organizer
      International Society of Nephrology, NEXUS-drug discovery
    • Place of Presentation
      Belgamo, Italy
    • Year and Date
      2014-04-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] A NON-TRANSCRIPTIONAL ROLE OF HYPOXIA-INDUCIBLE FACTOR (HIF)-1 IN DEFENSE AGAINST DNA DOUBLE STRAND INJURY.2014

    • Author(s)
      Tetsuhiro Tanaka, Yoshiki Higashijima, Shinji Tanaka, Junna Yamaguchi, Masaomi Nangaku
    • Organizer
      The 51st European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      Amsterdam, the Netherlands
    • Year and Date
      2014-06-02
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Diabetic nephropathy and metabolic memory: role of epigenetics.2014

    • Author(s)
      Masaomi Nangaku
    • Organizer
      45th Indian Society of Nephrology Conference.
    • Place of Presentation
      Kolkata, India
    • Year and Date
      2014-12-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Hypoxic HIF, Fibrosis, and CKD.2014

    • Author(s)
      Nangaku M
    • Organizer
      第47回アメリカ腎臓学会
    • Place of Presentation
      Philadelphia, U.S.A.
    • Year and Date
      2014-11-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111003
  • [Presentation] SIRT1 MAINTAINS ACTIN CYTOSKELETON BY DEACETYLATION OF CORTACTIN IN PODOCYTES2014

    • Author(s)
      Reiko Inagi, Shuta Motonishi, Masaomi Nangaku
    • Organizer
      The 51st European Renal Association/European Dialysis and Transplantation Association
    • Place of Presentation
      Amsterdam, the Netherlands
    • Year and Date
      2014-06-03
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Galacto-oligosaccharides modified gut microbiota and attenuated renal injury.2014

    • Author(s)
      Satoshi Unuma Furuse, Takamoto Ohse, Airi Jo-Watanabe, Akira Shigehisa, Koji Kawakami, Takahiro Matsuki, Osamu Chonan, Masaomi Nangaku
    • Organizer
      The 14th Asian Pacific Congress of Nephrology.
    • Place of Presentation
      東京
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-25461210
  • [Presentation] Long-Chain Saturated Fatty Acid-Induced Endoplasmic Reticulum Stress Suppresses Erythropoietin Production in Kidney.2014

    • Author(s)
      Thitinun Anusornvongchai, Chih-Kang Chiang, Yu Ishimoto, Norio Suzuki, Masayuki Yamamoto, Masaomi Nangaku, Reiko Inagi.
    • Organizer
      The 47th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-14
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] SIRT1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Podocytes.2014

    • Author(s)
      Shuta Motonishi, Masaomi Nangaku, Takehiko Wada, Yu Ishimoto, Taiji Matsusaka, Akira Shimizu, Reiko Inagi.
    • Organizer
      The 47th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-14
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] SIRT1 Maintains Podocyte Homeostasis via Regulation of Actin Fiber Formation2013

    • Author(s)
      Shuta Motonishi, Reiko Inagi, Takehiko Wada, Takamoto Ohse, Akira Shimizu, Masaomi Nangaku
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      Georgia World Congress Center(米国・アトランタ)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Circulating suPAR in Japanese Patients with Glomerular Diseases: A Multicenter Cross-Sectional Study2013

    • Author(s)
      Takehiko Wada, Masaomi Nangaku, Shoichi Maruyama, Enyu Imai, Kumi Shoji, Sawako Kato, Tomomi Endo, Eri Muso, Kouju Kamata, Hitoshi Yokoyama, Keiji Fujimoto, Yoko Obata, Tomoya Nishino, Hideki Kato, Shunya Uchida, Yoshie Sasatomi, Takao Saito, Seiichi Matsuo
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      Georgia World Congress Center(米国・アトランタ)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Glyoxalase Iによる血管内皮の糖化抑制とeNOSの活性制御を介した内皮機能障害の軽減と血管老化の進行抑制2013

    • Author(s)
      城 愛理, 大瀬 貴元, 稲城 玲子, 鵜沼 智, 池田 洋一郎, 和田 健彦, 宮田 敏男, 高橋 政夫, 西松 寛明, 平田 恭信, 南学 正臣
    • Organizer
      日本臨床分子医学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] 新規HIF-1ターゲット分子SPAG4は細胞質分裂を調節し、腎細胞癌の進行に重要な役割を果たす2013

    • Author(s)
      正路 久美, 村山 尚, 三村 維真理, 和田 健彦, 久米 春喜, 後藤 明輝, 大瀬 貴元, 田中 哲洋, 稲城 玲子, 油谷 浩幸, 児玉 龍彦, 南学 正臣
    • Organizer
      日本臨床分子医学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Glyoxalase I Prevents Age-Related Endothelial Dysfunction through Modulation of eNOS Phosphorylation2013

    • Author(s)
      Airi Jo, Takamoto Ohse, Hiroaki Nishimatsu, Masao Takahashi, Satoshi Unuma, Takehiko Wada, Yoichiro Ikeda, Toshio Miyata, Yasunobu Hirata, Reiko Inagi, Masaomi Nangaku
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      Georgia World Congress Center(米国・アトランタ)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Epigenetic modulation of renal ischemic response.2012

    • Author(s)
      Nangaku M
    • Organizer
      ISN Forefront Systems Biology and the Kidney.
    • Place of Presentation
      Michigan, USA(招待講演)
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Identification and Characterization of a Novel HIF-1 Target that Regulates Cytokinesis as a Defensive Mechanism against Polyploidy2012

    • Author(s)
      Kumi Shoji, Imari Mimura, Takashi Murayama, Takehiko Wada, Tetsuhiro Tanaka, Takamoto Ohse, Reiko Inagi, Hiroyuki Aburatani, Tatsuhiko Kodama, Masaomi Nangaku
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Abnormal Oxygen Metabolism and Epigenetic changes in Diabetic Kidney Disease2012

    • Author(s)
      Nangaku M
    • Organizer
      Keystone Symposium on Complications of Diabetes
    • Place of Presentation
      Boston, U. S. A.
    • Year and Date
      2012-03-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Abnormal Oxygen Metabolism and Epigenetic changes in Diabetic Kidney Disease2012

    • Author(s)
      Nangaku
    • Organizer
      Keystone Symposium on Complications of Diabetes
    • Place of Presentation
      Boston, U.S.A.(Invited)
    • Year and Date
      2012-03-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] 生活習慣病と癌における低酸素とHIFの役割の解明.2012

    • Author(s)
      南学正臣
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場、福岡 Japan(招待講演)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] 新規HIF-1ターゲット分子SPAG4は尿細管の細胞質分裂を調節する2012

    • Author(s)
      正路 久美, 村山 尚, 三村 維真理, 和田 健彦, 久米 春喜, 後藤 明輝, 大瀬 貴元, 田中 哲洋, 稲城 玲子, 油谷 浩幸, 児玉 龍彦, 南学 正臣, 藤田 敏郎
    • Organizer
      第55回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] 小胞体ストレスシグナル(unfolded protein response)による低酸素応答性エリスロポエチン産生機構の破綻2012

    • Author(s)
      Chiang Chih-Kang, 南学 正臣, 田中 哲洋, 和田 健彦, 大瀬 貴元, 藤田 敏郎, 稲城 玲子
    • Organizer
      第55回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Uremia and hypoxic organ damage: a long-term consequence.2012

    • Author(s)
      Nangaku M
    • Organizer
      30th International Society of Blood Purification.
    • Place of Presentation
      パシフィコ横浜 Japan(招待講演)
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells2012

    • Author(s)
      Shiyo Muratsu, Masaomi Nangaku, Yoichiro Ikeda, Tetsuhiro Tanaka, Takehiko Wada, Reiko Inagi
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] microRNAによるprolyl hydroxylase domain 1(PHD1)の転写後制御を介した腎尿細管細胞のストレス応答調節機構2012

    • Author(s)
      村津 四葉, 南学 正臣, 田中 哲洋, 池田 洋一郎, 和田 健彦, 大瀬 貴元, 藤田 敏郎, 稲城 玲子
    • Organizer
      第55回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Abnormal Oxygen Metabolism and Epigenetic changes in Diabetic Kidney Disease2012

    • Author(s)
      Nangaku M
    • Organizer
      Keystone Symposium on Complications of Diabetes
    • Place of Presentation
      Boston, U. S. A
    • Year and Date
      2012-03-12
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Identification of a Novel Hypoxia-Inducible Factor 1 (HIF-1) Regulator, CCAAT/Enhancer-Binding Protein Delta (CEBPD) in Kidney Disease2012

    • Author(s)
      Junna Yamaguchi, Tetsuhiro Tanaka, Nobuaki Eto, Takamoto Ohse, Takehiko Wada, MD, Reiko Inagi, Masaomi Nangaku
    • Organizer
      American Society of Nephrology Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Cellular Defense Systems in Hypoxia : Mechanisms for Renal Protection2011

    • Author(s)
      Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2011-04-11
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Identification & Characterization of a Novel Oncogenic HIF-1 Target Involved in Renal Cell Carcinoma2011

    • Author(s)
      Shoji K, Mimura I, Ohse T, Murayama T, Inagi R, Wada T, Tanaka T, Kume H, Goto A, Fujita T, Aburatani H, Kodama T, Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Mechanism of the development of renal anemia and its treatment2011

    • Author(s)
      Nangaku M
    • Organizer
      International Forum of Chronic Kidney Disease of the Taiwan Society of Nephrology
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2011-07-10
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Derangement of Oxygen Sensing for Erythropoietin(EPO) Production by Unfolded Protein Response2011

    • Author(s)
      Inagi R, Chiang CK, Tanaka T, Fujita T, Nangaku M
    • Organizer
      The 44th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in HIF-dependent manner2011

    • Author(s)
      Chiang CK, Inagi R, Tanaka T, Fujita T, Nangaku M
    • Organizer
      7^<th> International Congress on Uremia Research and Toxicity
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Progression of CKD following AKI2011

    • Author(s)
      Nangaku M
    • Organizer
      Role of hypoxia. The 44th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Indoxyl Sulfate Induces Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-Terminal Domain, 2, and Impairs Hypoxia Response in Proximal Tubular Cells2011

    • Author(s)
      Tanaka T, Fujita T, Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Progression of CKD following AKI : Role of hypoxia2011

    • Author(s)
      Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Indoxyl sulfate impairs hypoxia response in cultured proximal tubular cells2011

    • Author(s)
      Tanaka T, Fujita T, Nangaku M
    • Organizer
      7^<th> International Congress on Uremia Research and Toxicity
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Progression of CKD following AKI : Role of hypoxia2011

    • Author(s)
      Nangaku
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U.S.A.(Invited)
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Dysregulated oxygen metabolism of the kidney by uremic toxins2011

    • Author(s)
      Nangaku M
    • Organizer
      7^<th> International Congress on Uremia Research and Toxicity
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Identification & Characterization of a Novel OncogenicHIF-1 Target Involved in Renal Cell Carcinoma2011

    • Author(s)
      Shoji K, Mimura I, Ohse T, Murayama T, Inagi R, Wada T, Tanaka T, Kume H, GotoA, Fujita T, Aburatani H, Kodama T, Nangaku M
    • Organizer
      The 44th Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] HIF1 Modulates Chromatin Conformational Change by Recruiting KDM3A and Enhances Regulation of Glucose Transporter 3 in Endothelial Cells2011

    • Author(s)
      Mimura I, Inoue T, Wada Y, Kanki Y, Fujita T, Aburatani H, Kodama T, Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A.
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Dysregulated oxygen metabolism of the kidney by uremic toxins2011

    • Author(s)
      Nangaku
    • Organizer
      7^<th> International Congress on Uremia Research and Toxicity
    • Place of Presentation
      名古屋(Invited)
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] 貧血治療による腎保護効果のメカニズム2011

    • Author(s)
      南学正臣
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-16
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Mechanism of the development of renal anemia and its treatment2011

    • Author(s)
      Nangaku
    • Organizer
      International Forum of Chronic Kidney Disease of the Taiwan Society of Nephrology
    • Place of Presentation
      Taipei, Taiwan(Invited)
    • Year and Date
      2011-07-10
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Mechanism of the development of renal anemia and its treatment2011

    • Author(s)
      Nangaku M
    • Organizer
      International Forum of Chronic Kidney Disease of the Taiwan Society of Nephrology
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2011-07-10
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Renal Ischemia Reperfusion Injury Promotes Mid-Term Tubular Senescence2011

    • Author(s)
      Ikeda T, Inagi R, Fujita T, Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Cellular Defense Systems in Hypoxia : Mechanisms for Renal Protection.2011

    • Author(s)
      Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2011-04-11
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] 酸化ストレスおよび小胞体(ER)ストレス応答における腎尿細管細胞のmicroRNA発現変動2011

    • Author(s)
      村津四葉、南学正臣、田中哲洋、Chih-KangChiang、和田健彦、藤田敏郎、稲城玲子
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Cellular Defense Systems in Hypoxia : Mechanisms for Renal Protection2011

    • Author(s)
      Nangaku
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Vancouver, Canada(Invited)
    • Year and Date
      2011-04-11
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Derangement of Oxygen Sensing for Erythropoietin(EPO) Production by Unfolded Protein Response(UPR)2011

    • Author(s)
      Inagi R, Chiang CK, Tanaka T, Fujita T, Nangaku M
    • Organizer
      The 44^<th> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Philadelphia, U. S. A
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Elucidation of the Anti-Fibrotic Mechanism of a Novel HIF-Regulated Globin, Cytoglobin, with Molecular Genetics2010

    • Author(s)
      Mimura I, Nishi H, Tanaka T, Inagi R, Fujita T, Nangaku M
    • Organizer
      The 43^<rd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] HIF and Renal Disease2010

    • Author(s)
      Nangaku M
    • Organizer
      12th Asian Pacific Congress of Nephrology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-06-06
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Role of hypoxia in chronic kidney disease2010

    • Author(s)
      Nangaku M
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Saxton River, U. S. A
    • Year and Date
      2010-06-29
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Defensive mechanisms against fibrosis in the hypoxic kidney. ISN-NEXUS2010

    • Author(s)
      Nangaku M
    • Organizer
      fibrosis and the kidney
    • Place of Presentation
      Switzerland
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] MicroRNA Profiles of Tubular Cells under Hypoxia-Reoxygenation and Endoplasmic Reticulum Stress2010

    • Author(s)
      Muratsu S, Nangaku M, Tanaka T, Chiang CK, Wada T, Fujita T, Inagi R
    • Organizer
      The 43^<rd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Endoplasmic Reticulum Stress Disturbs Erythropoietin Gene Expression in a HIF-Dependent Manner2010

    • Author(s)
      Chiang CK, Nangaku M, Tanaka T, Fujita T, Inagi R
    • Organizer
      The 43^<rd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] The evaluation of renal senescence and its retardation by the reduction of carbonyl stress2010

    • Author(s)
      Ikeda Y, Nangaku M, Inagi R, Kumagai T, Miyata T, Fujita T
    • Organizer
      ISN-NEXUS : the kidney and the vascular system
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Impact of Anthracyclines on Hypoxia Response in Tubular Epithelial Cells2010

    • Author(s)
      Tanaka T, Fujita T, Nangaku M
    • Organizer
      The 43^<rd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] MicroRNA Profiles of Tubular Cells under Hypoxia-Reoxygenation and Endoplasmic Reticulum Stress2010

    • Author(s)
      Muratsu S, Nangaku M, Tanaka T, Chiang CK, Wada T, Fujita T, Inagi R
    • Organizer
      The 43rd Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A.
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Identification of novel targets of hypoxia-responsive pathways2010

    • Author(s)
      Nangaku M
    • Organizer
      ISN-NEXUS : the kidney and the vascular system
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Defensive mechanisms against fibrosis in the hypoxic kidney2010

    • Author(s)
      Nangaku M
    • Organizer
      ISN-NEXUS : fibrosis and the kidney
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Defensive mechanisms against fibrosis in the hypoxic kidnev.2010

    • Author(s)
      Nangaku (invited)
    • Organizer
      ISN-NEXUS
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Identification of novel targets of hypoxia-responsive pathways2010

    • Author(s)
      Nangaku M
    • Organizer
      ISN-NEXUS : the kidney and the vascularsystem
    • Place of Presentation
      Japan
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Role of carbonyl stress in renal senescence2010

    • Author(s)
      Nangaku M, Ikeda Y, Fujita T, Inagi R
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Otsu, Japan
    • Year and Date
      2010-10-06
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Endoplasmic Reticulum Stress Disturbs Erythropoietin Gene Expression ina HIF-Dependent Manner.2010

    • Author(s)
      Chiang CK, Nangaku M, Tanaka T, Fujita T, Inagi R
    • Organizer
      The 43rd Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Role of carbonyl stress in renal senescence.2010

    • Author(s)
      Nangaku, et al.
    • Organizer
      FASEB summer research conference
    • Place of Presentation
      Otsu, Japan
    • Year and Date
      2010-10-06
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Genome-wide analysis of hypoxic inducible factor 1 binding sites in human endothelial cells under hypoxia2010

    • Author(s)
      Mimura I, Wada Y, Tsutsumi S, Aburatani H, Kodama T, Nangaku M
    • Organizer
      ISN-NEXUS : the kidney and the vascular system
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Identification of novel targets of hypoxia-responsive pathways.2010

    • Author(s)
      Nangaku (invited)
    • Organizer
      ISN-NEXUS
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Impaired glomerular healing with persistent glomerular inflammation in streptozotocin-induced diabetic nephropathy2010

    • Author(s)
      Takano H, Shimizu A, Wakamatsu K, Ishikawa A, Masuda Y, Ishizaki M, Nangaku M, Fukuda Y
    • Organizer
      ISN-NEXUS : the kidney and the vascular system
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] HIF and renal disease.2010

    • Author(s)
      Nangaku (invited)
    • Organizer
      12^<th> Asian Pacific Congress of Nephrology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-06-06
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Glyoxalase I Prevent Age-Related Aortic Medial Thickening by Reducing TGF-βand CTGF Signals Independent of Blood Pressure2010

    • Author(s)
      Ikeda T, Inagi R, Jo A, Ohse T, Miyata T, Manabe I, Nagai R, Fujita T, Nangaku M
    • Organizer
      The 43^<rd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Denver, U. S. A
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] HIF and Renal Disease2010

    • Author(s)
      Nangaku M
    • Organizer
      12^<th> Asian Pacific Congress of Nephrology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-06-06
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Role of hypoxia in chronic kidney disease. FASEB Summer Research Conference2010

    • Author(s)
      Nangaku M
    • Organizer
      Saxton River
    • Place of Presentation
      U. S. A
    • Year and Date
      2010-06-29
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] AKIの発症機序の概説2010

    • Author(s)
      南学正臣
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Role of hypoxia in chronic kidney disease.2010

    • Author(s)
      Nangaku (invited)
    • Organizer
      FASEB summer research conference
    • Place of Presentation
      Saxtons River, Vermont U.S.A.
    • Year and Date
      2010-06-29
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Cytoglobin, a novel member of the globin family, protects the kidney fibroblasts against oxidative stress under ischemic conditions2009

    • Author(s)
      Nishi H, Inagi R, Kawada N, Yoshizato K, Mimura I, Miyata T, Fujita T, Nangaku M
    • Organizer
      The 42^<nd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, U. S. A
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Acute Administration of Indoxyl Sulfate Increases the Glomerular Filtration Rate and Reduces Kidney Oxygenation, but without Affecting Renal Blood Flow2009

    • Author(s)
      Palm F, Gutweiler A, Welch WJ, Wilcox CS, Nangaku M
    • Organizer
      The 42^<nd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Diego, U. S. A
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Genome-wide analysis of hypoxic inducible factor 1 binding sites in human endothelial cells under hypoxia2009

    • Author(s)
      Mimura I, Nishi H, Inagi R, Fujita T, Nangaku M
    • Organizer
      The 42^<nd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, U. S. A
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Endoplasmic reticulum stress inducesautophagy in renal proximal tubular cells2009

    • Author(s)
      Kawakami T, Inagi R, Takano H, Sato S, Ingelfinger J, Miyata T, Fujita T, Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Italy
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2009

    • Author(s)
      Kawakami T, Inagi R, Fujita T, Nangaku M
    • Organizer
      The 42^<nd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, U. S. A
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats2009

    • Author(s)
      Kumagai T, Nangaku M, Kojima I, Nishi H, Tanaka T, Miyata T, Fujita T, Inagi R
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2009-05-24
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Hypoxia-induced endoplasmic reticulum stress is ameliorated by glyoxalase I via reduction of intraWorld Congress of Nephrologycellular oxidative stress2009

    • Author(s)
      Inagi R, Nishi H, Tanaka T, Miyata T, Fujita T, Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2009-05-25
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Transgenic overexpression of cytoglobin, a novel globin protein, improves tubulointerstitial injury via amelioration of oxidative stress in the hypoxic kidney2009

    • Author(s)
      Nishi H, Inagi R, Kawada N, Yoshizato K, Miyata T, Mimura I, Fujita T, Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2009-05-25
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] 尿毒素による尿細管細胞の酸素代謝異常2009

    • Author(s)
      南学正臣
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] The renin-angiotensin system as a cause of renal hypoxia2009

    • Author(s)
      Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2009-05-24
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2009

    • Author(s)
      Kawakami T, Inagi R, Fujita T, Nangaku M
    • Organizer
      The 42ndAnnual Meeting of the American Society of Nephrology
    • Place of Presentation
      U. S. A
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Hypoxia-induced endoplasmic reticulum stress is amelioratedby glyoxalase I via reduction of intracellular oxidative stress2009

    • Author(s)
      Inagi R, Nishi H, Tanaka T, Miyata T, Fujita T, Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Italy
    • Year and Date
      2009-05-25
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] 尿毒症と酸素代謝異常2009

    • Author(s)
      南学正臣(invited)
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Abnormal oxygen metabolism in diabetic kidney2009

    • Author(s)
      南学正臣(invited)
    • Organizer
      第21回日本糖尿病性腎症研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] 貧血の治療目標とその実際2009

    • Author(s)
      南学正臣
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Glyoxalase1 attenuates the impact of renal aging2009

    • Author(s)
      Ikeda Y, Inagi R, Miyata T, Fujita T, Nangaku M
    • Organizer
      The 42^<nd> Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, U. S. A.
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Glyoxalase1 attenuates the impact of renal aging2009

    • Author(s)
      Ikeda Y, Nangaku M, Kumagai T, Miyata T, Inagi R
    • Organizer
      10th International Symposium on the Maillard Reaction
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] CKDの発症・進展に関する基礎研究2009

    • Author(s)
      南学正臣(invited)
    • Organizer
      第31回腎臓セミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-08-31
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats2009

    • Author(s)
      Kumagai T, Nangaku M, Kojima I, Nishi H, Tanaka T, Miyata T, Fujita T, Inagi R
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Italy
    • Year and Date
      2009-05-24
    • Data Source
      KAKENHI-PROJECT-21591020
  • [Presentation] Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells2009

    • Author(s)
      Kawakami T, Inagi R, Takano H, Sato S, Ingelfinger J, Miyata T, Fujita T, Nangaku M
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-21390260
  • [Presentation] A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia2008

    • Author(s)
      Nangaku, et.al.
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Presentation] A novel class ofprolyl hydroxylase inhibitors inducesangiogenesis and exerts organprotection against ischemia2008

    • Author(s)
      Nangaku M, et.al.
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Presentation] A novel class of prolyl hydroxylase inhibitors induces angriogenesis and exerts organ protection against ischemia.2008

    • Author(s)
      Nangaku, M et al.
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Vapcouver, Canada
    • Data Source
      KAKENHI-PROJECT-19590939
  • [Presentation] A Novel Class of Prolyl Hydroxylase Inhibitors Induces Angiogenesis and Exerts Organ Protection Against Ischemia2007

    • Author(s)
      Nangaku M, et. al.
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      San Francisco,USA
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Presentation] A Novel Class of Prolyl Hydroxylase Inhibitors Induces Angiogenesis and Exerts Organ Protection Against Ischemia2007

    • Author(s)
      Nangaku, et.al.
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-19390228
  • [Presentation] Galacto-Oligosaccharides Modified Gut Microbiota and Attenuated Renal Injury

    • Author(s)
      Satoshi Unuma, Takamoto Ohse, Airi Jo, Akira Shigehisa, Koji Kawakami, Takahiro Matsuki, Osamu Chonan, Masaomi Nangaku
    • Organizer
      Annual meeting of American Society of Nephrology
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-25461210
  • [Presentation] ラットThy-1腎炎モデルにおけるDPP-4阻害薬の腎保護効果に関する検討

    • Author(s)
      東島佳毅、田中哲洋、山口純奈、田中真司、南学正臣
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-05 – 2015-06-07
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] 慢性腎臓病において低酸素が酸化ストレス障害に拮抗する新規分子機構

    • Author(s)
      田中哲洋、田中真司、山口純奈、東島佳毅、南学正臣
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Presentation] Galacto-oligosaccharide modified gut microbiota and attenuated the renal injury

    • Author(s)
      Satoshi Unuma, Takamoto Ohse, Airi Jo, Akira Shigehisa, Koji Kawakami, Takahiro Matsuki, Osamu Chonan, Masaomi Nangaku
    • Organizer
      International congress on uremia research and toxicity
    • Place of Presentation
      沖縄(沖縄コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-25461210
  • [Presentation] Indoxyl Sulfate Signals for Rapid mRNA Stabilization of Cbp/p300-Interacting Transactivator with Glu/Asp-Rich Carboxy-Terminal Domain 2 (CITED2) and Suppresses the Expression of Hypoxia-Inducible Genes in Experimental CKD and Uremia.

    • Author(s)
      Tetsuhiro Tanaka, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] SIRT1はpodocyteにおいてcortactinを脱アセチル化しアクチン細胞骨格を防御する

    • Author(s)
      本西秀太、南学正臣、和田健彦、石本遊、松阪泰二、清水章、稲城玲子
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-07-04 – 2014-07-06
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] Galacto-Oligosaccharides Modified Gut Microbiota and Attenuated Renal Injury.

    • Author(s)
      Satoshi Unuma, Takamoto Ohse, Airi Jo, Akira Shigehisa, Koji Kawakami, Takahiro Matsuki, Osamu Chonan, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] SIRT1 Maintains Podocyte Homeostasis via Regulation of Actin Fiber Formation.

    • Author(s)
      Shuta Motonishi, Reiko Inagi, Takehiko Wada, Takamoto Ohse, Akira Shimizu, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] combat with kidney disease: current and future

    • Author(s)
      Nangaku M.
    • Organizer
      50th Anniversary of Dialysis in Taiwan
    • Place of Presentation
      Taipei, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Hypoxia as a converging pathway in renal fibrosis.

    • Author(s)
      Nangaku M.
    • Organizer
      Satellite Symposium on renal fibrosis of 7th World Congress of Nephrology
    • Place of Presentation
      Guangzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Hypoxia and fibrosis of the kidney

    • Author(s)
      Nangaku M.
    • Organizer
      International Symposium "Frontiers in Renal Disease Research”
    • Place of Presentation
      Daejeon, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Optimal Hemoglobin Target Might Be Different between Elderly Hemodialysis Patients and Non-Elderly Patients.

    • Author(s)
      Norio Hanafusa, Takanobu Nomura, Takeshi Hasegawa, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Breathless: Dynamic Changes in Chromatin Conformation in Renal Hypoxia.

    • Author(s)
      Nangaku M
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] An Antifibrotic Role of Hypoxia-Inducible Factor 3 in Renal Tubular Cells.

    • Author(s)
      Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] 糸球体疾患の最近の進歩 FSGSとaHUS

    • Author(s)
      南学正臣、和田健彦、加藤秀樹.
    • Organizer
      第44回日本腎臓学会東部学術大会
    • Place of Presentation
      ベルサール新宿グランド(東京都新宿区)
    • Year and Date
      2014-10-24 – 2014-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] SIRT1 はアクチン線維形成の制御を介して糸球体足細胞の恒常性を維持する

    • Author(s)
      本西 秀太、南学 正臣、和田 健彦、石本 遊、清水 章、稲城 玲子
    • Organizer
      第4回腎不全研究会
    • Place of Presentation
      全社協・灘尾ホール(東京)
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] A non-transcriptional role of hypoxia-inducible factor (hif)-1 in defense against dna double strand injury

    • Author(s)
      Tetsuhiro Tanaka, Yoshiki Higashijima, Shinji Tanaka, Junna Yamaguchi, Masaomi Nangaku
    • Organizer
      ERA-EDTA 51st meeting
    • Place of Presentation
      Amsterdam
    • Year and Date
      2014-05-31 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-26461215
  • [Presentation] Actin cytoskeletal rearrangement by SIRT1 in podocytes

    • Author(s)
      本西秀太、南学正臣、稲城玲子
    • Organizer
      第37回基礎老化学会
    • Place of Presentation
      愛知
    • Year and Date
      2014-06-26 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25461207
  • [Presentation] Toward the podocyte protection therapy.

    • Author(s)
      Nangaku M.
    • Organizer
      7th World Congress of Nephrology
    • Place of Presentation
      Hong Kong
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Role of Uremic Toxins in ESA Resistance in Dialysis Patients

    • Author(s)
      Nangaku M.
    • Organizer
      8th International Congress on Uremia Research and Toxicity
    • Place of Presentation
      Okinawa, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] 飽和脂肪酸(パルミンチン酸)は小胞体ストレスを介して腎EPO産生細胞の機能破綻を招く

    • Author(s)
      Anusornvongchai Thitinun、本西秀太、鈴木教郎、山本雅之、南学正臣、稲城玲子
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-05 – 2015-06-07
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] SIRT1 maintains actin cytoskeleton by deacetylation of cortactin in podocytes

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Matsusaka T, Shimizu A, Inagi R
    • Organizer
      Kidney Week 2014
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-13 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-24591189
  • [Presentation] The Mechanism of ANGPTL4 Induction, a Mediator of Nephrotic Syndrome, through Its Chromatin Conformational Change.

    • Author(s)
      Tsuyoshi Inoue, Imari Mimura, Takahide Kohro, Toshiya Tanaka, Hiroyuki Aburatani, Tatsuhiko Kodama, Youichiro Wada, Masaomi Nangaku
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Induction of CCAAT/Enhancer-Binding Protein Delta (CEBPD) Links Inflammation and Hypoxia to Injury by Regulating Hypoxia-Inducible Factor 1 (HIF-1).

    • Author(s)
      Junna Yamaguchi, Tetsuhiro Tanaka, Nobuaki Eto, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • [Presentation] Glyoxalase I Prevents Age-Related Endothelial Dysfunction through Modulation of eNOS Phosphorylation.

    • Author(s)
      Airi Jo, Takamoto Ohse, Hiroaki Nishimatsu, Masao Takahashi, Satoshi Unuma, Takehiko Wada, Yoichiro Ikeda, Toshio Miyata, Yasunobu Hirata, Reiko Inagi, Masaomi Nangaku.
    • Organizer
      The 46th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390213
  • []

  • 1.  INAGI Reiko (50232509)
    # of Collaborated Projects: 24 results
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  • 2.  TANAKA Tetsuhiro (90508079)
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  • 3.  WADA Takehiko (90447409)
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  • 4.  Kawakami Takahisa (10722093)
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    # of Collaborated Products: 8 results
  • 5.  OHSE Takamoto (10568447)
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  • 6.  西 裕志 (90784174)
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    # of Collaborated Products: 6 results
  • 7.  Kato Hideki (90625237)
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  • 8.  三村 維真理 (00727084)
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  • 9.  平川 陽亮 (10780736)
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  • 10.  HANAFUSA Norio (90396739)
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  • 11.  KODAMA Tatsuhiko (90170266)
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  • 12.  ABURATANI Hiroyuki (10202657)
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    # of Collaborated Products: 5 results
  • 13.  Mori Yasuo (80212265)
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  • 14.  OKUDA Toshihiro (80177170)
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  • 17.  浦野 泰照 (20292956)
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  • 18.  飛田 成史 (30164007)
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  • 19.  山本 雅之 (50166823)
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  • 20.  中川 秀彦 (80281674)
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  • 21.  三木 裕明 (80302602)
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  • 22.  武田 憲彦 (40422307)
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  • 23.  吉田 瑶子 (90649443)
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  • 24.  井上 正宏 (10342990)
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  • 25.  正路 久美 (00439423)
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  • 26.  長谷川 頌 (30892658)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 27.  JO Airi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 28.  ISHIMOTO Yu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 29.  OKADA Akira
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 30.  MIURA kyoko
    # of Collaborated Projects: 2 results
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  • 31.  SUMIMOTO hideki
    # of Collaborated Projects: 2 results
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  • 32.  ITOH ken
    # of Collaborated Projects: 2 results
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  • 33.  UCHIDA kouji
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  • 34.  Hirata Yoshihiro (10529192)
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  • 36.  MARUYAMA Toshiyuki (30219571)
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  • 37.  MATSUMOTO Yoichiro (60111473)
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  • 38.  TAKAGI Shu (30272371)
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  • 39.  KOIKE Kazuhiko (80240703)
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  • 40.  HIRAYAMA Noriaki (70238393)
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  • 41.  合田 亘人 (00245549)
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  • 42.  西田 基宏 (90342641)
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  • 43.  饒 梓明 (30772446)
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  • 44.  藤井 輝夫 (30251474)
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  • 45.  井上 剛 (30821665)
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  • 46.  池田 洋一郎 (10407398)
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  • 47.  木村 啓志 (40533625)
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  • 48.  平林 祐介 (80447391)
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  • 50.  Unuma Satoshi
    # of Collaborated Projects: 1 results
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  • 51.  SUEMATSU makoto
    # of Collaborated Projects: 1 results
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  • 52.  SOGA tomoyoshi
    # of Collaborated Projects: 1 results
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  • 53.  TANIGUCHI naoyuki
    # of Collaborated Projects: 1 results
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  • 54.  UMEMURA Shinichiro
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  • 55.  Shinohara Akinari
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  • 56.  Nasu Kahori
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  • 57.  DOI Kotaro
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  • 58.  CHIKAMORI Masatomo
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  • 59.  TOKUNAGA Katsushi
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  • 60.  UEDA Hiroki
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  • 61.  NOSO Shinsuke
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  • 62.  SAKAMOTO Takeharu
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  • 63.  KAGAMI Shoji
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  • 64.  Kubota Naoto
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  • 65.  倉田 遊
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  • 66.  宮田 敏行
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  • 68.  永井 竜児
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  • 69.  洲崎 悦生
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  • 70.  池上 博司
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  • 71.  松阪 泰二
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  • 72.  菅原 真衣
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  • 73.  呉 家賢
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  • 74.  野村 征太郎
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    # of Collaborated Products: 1 results
  • 75.  桜井 賛孝
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