Tsubota Akihito 坪田昭人

… Alternative Names

TSUBOTA Akihito 坪田昭人

TSUBOTA Akihiko 坪田昭人

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Researcher Number	90322643
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東京慈恵会医科大学, 医学部, 教授 2019 – 2023: 東京慈恵会医科大学, 医学部, 教授 2012 – 2017: 東京慈恵会医科大学, 医学部, 教授 2011: 東京慈恵会医科大学, 医学部, 准教授 2005 – 2006: 東京慈恵会医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Gastroenterology / Laboratory animal science Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator B型肝炎ウイルス / B型肝炎 / GeneChip / microRNA / mRNA / 網羅的遺伝子発現解析 / 酸化ストレス / 肝発癌 / 潜在性C型肝炎ウイルス / ウイルス学的持続陰性 … More / C型慢性肝炎 / 肝細胞内オルガネラ / 肝細胞内微細構造 / occult hepatitis C virus / SVR / C型肝炎ウイルス / C型慢性肝疾患 / 慢性感染 / miRNA / 肝炎慢性化 / トランスクリプトーム解析 / ヒト化肝臓キメラマウス / tumorigenesis / liver carcinogenesis / Oligonucleotide microarray-based genome-wide analysis of gene expressio / oxidative stress / reactive oxygen species / 腫瘍原性 / 活性酸素種 / 網羅的解析 / siRNA / 肝腫瘍原性遺伝子 … More Except Principal Investigator 幹細胞 / 型破り分泌蛋白質 / バイオマーカー / 型破り分泌蛋白 / 早期診断 / 肝癌 Less

HBVゲノムの取り込みパターンと血中/尿中キメラDNAの肝癌再発における意義Principal Investigator
- Principal Investigator
  
  坪田昭人
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Jikei University School of Medicine
肝癌特異的な細胞外分泌蛋白を用いた新規早期診断法確立とその実用化に向けた検証研究
- Principal Investigator
  
  及川恒一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jikei University School of Medicine
Intrahepatocellular organelle abnormalities and occult HCV that remain long-term after HCV eliminationPrincipal Investigator
- Principal Investigator
  
  坪田昭人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Jikei University School of Medicine
Elucidation of the stealth mechanism of infection chronicity by hepatitis B virus and drug discovery of inhibitory molecular targetsPrincipal Investigator
- Principal Investigator
  
  Tsubota Akihito
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Jikei University School of Medicine
Integrating multiple omics analysis for understanding the pathological mechanism of chronic hepatitis B virus infection and identifying potential molecular targets using humanized chimeric micePrincipal Investigator
- Principal Investigator
  
  TSUBOTA Akihito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Jikei University School of Medicine
Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatmentPrincipal Investigator
- Principal Investigator
  
  TSUBOTA Akihito
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
Oligonucleotide microarray-based genome-wide analysis of gene expression in oxidative stress-induced hepatitis and tumorigenesisPrincipal Investigator
- Principal Investigator
  
  TSUBOTA Akihiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] Management of Gastric Cancer: Chapter 42011
- Author(s)
  Tsubota A, Koyama T, Namiki Y, Tada N, Takahashi H.
- Total Pages
  16
- Publisher
  InTech Open Access Publisher
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Low vitamin D levels accelerates muscle mass loss in patients with chronic liver disease2024
- Author(s)
  Okubo Tomomi、Atsukawa Masanori、Tsubota Akihito、Ono Hiroki、Kawano Tadamichi、Yoshida Yuji、Arai Taeang、Hayama Korenobou、Itokawa Norio、Kondo Chisa、Iwakiri Katsuhiko
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 3 Pages: e0299313-e0299313
- DOI
  10.1371/journal.pone.0299313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Association of chronic liver disease with bone diseases and muscle weakness2024
- Author(s)
  Saeki Chisato、Saito Mitsuru、Tsubota Akihito
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 1 Feb 2024 Issue: 4 Pages: 1-14
- DOI
  10.1007/s00774-023-01488-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma.2024
- Author(s)
  Nakagawa C, Oikawa T , Yamada K, Tsubota A, Saeki C, Katagiri K, Tago N, Kamioka H, Ueda K, Haruki K, Furukawa K, Nakano M, Torisu Y, Ikegami T, Yoshida K, Saruta M
- Journal Title
  
  Biomarkers
  
  Volume: 29 Issue: 2 Pages: 55-67
- DOI
  10.1080/1354750x.2024.2312990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08063, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-21K08718
[Journal Article] Protein Kinase C Delta Is a Novel Biomarker for Hepatocellular Carcinoma.2023
- Author(s)
  Oikawa T, Yamada K, Tsubota A, Saeki C, Tago N, Nakagawa C, Ueda K, Kamioka H, Taniai T, Haruki K, Nakano M, Torisu Y, Ikegami T, Yoshida K, and Saruta M.
- Journal Title
  
  Gastro Hep Advances
  
  Volume: 2 Issue: 1 Pages: 83-95
- DOI
  10.1016/j.gastha.2022.07.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08063, KAKENHI-PROJECT-20H03519, KAKENHI-PROJECT-20K07621
[Journal Article] Hepatocellular organellar abnormalities following elimination of hepatitis C virus2023
- Author(s)
  Aoyagi H, Iijima H, Gaber ES, Zaitsu T, Matsuda M, Wakae K, Watashi K, Suzuki R, Masaki T, Kahn J, Saito T, El-Kassas M, Shimada N, Kato K, Enomoto M, Hayashi K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Muramatsu M, Wake K, Wakita T, Aizaki H
- Journal Title
  
  Liver International
  
  Volume: 43 Issue: 8 Pages: 1677-1690
- DOI
  10.1111/liv.15624
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-23K27415
[Journal Article] Insulin-like growth factor 1 predicts decompensation and long-term prognosis in patients with compensated cirrhosis2023
- Author(s)
  Saeki Chisato、Kanai Tomoya、Ueda Kaoru、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 10 Pages: 1233928-1233928
- DOI
  10.3389/fmed.2023.1233928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Plasma pentosidine as a useful biomarker of sarcopenia, low gait speed, and mortality in patients with cirrhosis2023
- Author(s)
  Saeki Chisato、Saito Mitsuru、Tsubota Akihito
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 10 Pages: 1212899-1212899
- DOI
  10.3389/fmed.2023.1212899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] The Geriatric Nutritional Risk Index predicts sarcopenia in patients with cirrhosis2023
- Author(s)
  Saeki Chisato、Kinoshita Akiyoshi、Kanai Tomoya、Ueda Kaoru、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3888-3888
- DOI
  10.1038/s41598-023-31065-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-22K08587
[Journal Article] How do the 2022 <scp>European Society of Cardiology</scp>/<scp>European Respiratory Society</scp> guidelines modify the diagnosis of <scp>portopulmonary hypertension</scp> in patients with cirrhosis complicated by portal hypertension? A post hoc analysis2023
- Author(s)
  Atsukawa Masanori、Tsubota Akihito、Tamura Yuichi、Koyano‐Shioda Kaori、Kawano Tadamichi、Okubo Tomomi、Hayama Korenobu、Arai Taeang、Itokawa Norio、Taniguchi Yu、Tamura Yudai、Kondo Chisa、Iwakiri Katsuhiko
- Journal Title
  
  JGH Open
  
  Volume: 7 Issue: 8 Pages: 588-590
- DOI
  10.1002/jgh3.12949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] A versatile method to profile hepatitis B virus DNA integration2023
- Author(s)
  Fukano Kento、Wakae Kousho、Nao Naganori、Saito Masumichi、Tsubota Akihito、Toyoshima Takae、Aizaki Hideki、Iijima Hiroko、Matsudaira Takahiro、Kimura Moto、Watashi Koichi、Sugiura Wataru、Muramatsu Masamichi
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 12
- DOI
  10.1097/hc9.0000000000000328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-22K15481, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] Low geriatric nutritional risk index predicts poor prognosis in patients with cirrhosis: a retrospective study2023
- Author(s)
  Kamioka Hiroshi、Saeki Chisato、Kinoshita Akiyoshi、Nakagawa Chika、Kanai Tomoya、Ueda Kaoru、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 10 Pages: 1269399-1269399
- DOI
  10.3389/fnut.2023.1269399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Osteosarcopenia predicts poor survival in patients with cirrhosis: a retrospective study2023
- Author(s)
  Saeki Chisato、Kanai Tomoya、Ueda Kaoru、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 23 Issue: 1 Pages: 196-196
- DOI
  10.1186/s12876-023-02835-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Prognostic significance of sarcopenia and severe vitamin D deficiency in patients with cirrhosis2023
- Author(s)
  Saeki Chisato、Kanai Tomoya、Ueda Kaoru、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  JGH Open
  
  Volume: 7 Issue: 5 Pages: 351-357
- DOI
  10.1002/jgh3.12900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587
[Journal Article] Mac‐2‐binding protein glycan isomer predicts all malignancies after sustained virological response in chronic hepatitis C2022
- Author(s)
  Kawata Kazuhito、Watanabe Tsunamasa、Tsubota Akihito
- Journal Title
  
  Hepatology Communications
  
  Volume: - Issue: 8 Pages: 1-15
- DOI
  10.1002/hep4.1941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-22K08587
[Journal Article] Shorter pruritus period and milder disease stage are associated with response to nalfurafine hydrochloride in patients with chronic liver disease2022
- Author(s)
  Kawano Tadamichi、Atsukawa Masanori、Tsubota Akihito、Shimada Noritomo、Toyoda Hidenori、Takaguchi Koichi、Tani Joji、Morishita Asahiro、Hiraoka Atsushi、Mikami Shigeru、Ishikawa Toru、Okubo Hironao、Watanabe Tsunamasa、Okubo Tomomi、Arai Taeang、Hayama Korenobu、Itokawa Norio、Kondo Chisa、Iwakiri Katsuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 7311-7311
- DOI
  10.1038/s41598-022-11431-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] Clinical outcomes of antithrombin?III‐based therapy for patients with portal vein thrombosis: A retrospective, multicenter study2022
- Author(s)
  Hayama Korenobu、Atsukawa Masanori、Uojima Haruki、Hidaka Hisashi、Furuichi Yoshihiro、Kato Keizo、Kawata Kazuhito、Chuma Makoto、Nozaki Akito、Hiraoka Atsushi、Watanabe Tsunamasa、Kagawa Tatehiro、Toyoda Hidenori、Taniai Nobuhiko、Yoshida Hiroshi、Tanaka Yasuhito、Iwakiri Katsuhiko
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 1 Pages: 51-60
- DOI
  10.1111/hepr.13840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08811, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-22K08587
[Journal Article] Antifibrotic effect and long‐term outcome of <scp>SGLT</scp> 2 inhibitors in patients with <scp>NAFLD</scp> complicated by diabetes mellitus2022
- Author(s)
  Arai Taeang、Atsukawa Masanori、Tsubota Akihito、et al.
- Journal Title
  
  Hepatology Communications
  
  Volume: 6 Issue: 11 Pages: 3073-3082
- DOI
  10.1002/hep4.2069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] SEB genotyping: SmartAmp-Eprimer binary code genotyping for complex, highly variable targets applied to HBV2022
- Author(s)
  Delobel Diane、Furutani Yutaka、Nagoshi Sumiko、Tsubota Akihito、Miyasaka Akio、Watashi Koichi、Wakita Takaji、Matsuura Tomokazu、Usui Kengo
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 22 Issue: 1 Pages: 516-516
- DOI
  10.1186/s12879-022-07458-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] Serum Insulin-Like Growth Factor 1 Levels, Facture Risk Assessment Tool Scores and Bone Disorders in Patients with Primary Biliary Cholangitis2022
- Author(s)
  Saeki Chisato、Oikawa Tsunekazu、Ueda Kaoru、Nakano Masanori、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Diagnostics
  
  Volume: 12 Issue: 8 Pages: 1957-1957
- DOI
  10.3390/diagnostics12081957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] Misunderstanding of hepatitis C virus (HCV) infection status by non?specialized medical doctors in patients who achieved sustained virologic response to anti-HCV therapy2022
- Author(s)
  Toyoda Hidenori、Yasuda Satoshi、Moriya Akio、Itobayashi Ei、Uojima Haruki、Watanabe Tsunamasa、Atsukawa Masanori、Arai Taeang、Ishikawa Toru、Mikami Shigeru、Hiraoka Atsushi、Tsuji Kunihiko、Oikawa Tsunekazu、Tsubota Akihito、Nozaki Akito、Chuma Makoto、Abe Hiroshi、Shima Toshihide、Kumada Takashi、Tanaka Junko
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 28 Issue: 9 Pages: 1231-1234
- DOI
  10.1016/j.jiac.2022.04.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] Efficacy and safety of oral semaglutide in patients with non‐alcoholic fatty liver disease complicated by type 2 diabetes mellitus: A pilot study2022
- Author(s)
  Arai Taeang、Atsukawa Masanori、Tsubota Akihito、Ono Hirotaka、Kawano Tadamichi、Yoshida Yuji、Okubo Tomomi、Hayama Korenobu、Nakagawa‐Iwashita Ai、Itokawa Norio、Kondo Chisa、Nagao Mototsugu、Iwakiri Katsuhiko
- Journal Title
  
  JGH Open
  
  Volume: 6 Issue: 7 Pages: 503-511
- DOI
  10.1002/jgh3.12780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937
[Journal Article] Risk factors for portopulmonary hypertension in patients with cirrhosis: a prospective, multicenter study2022
- Author(s)
  Atsukawa Masanori、Tsubota Akihito、Kondo Chisa、et al.
- Journal Title
  
  Hepatology International
  
  Volume: 17 Issue: 1 Pages: 139-149
- DOI
  10.1007/s12072-022-10456-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-22K08587
[Journal Article] Identification of circulating microRNAs as potential biomarkers for hepatic necroinflammation in patients with autoimmune hepatitis2022
- Author(s)
  Saeki Chisato、Matsuzaki Juntaro、Kuroda Masahiko、Fujita Koji、Ichikawa Makiko、Takizawa Satoko、Takano Keiko、Oikawa Tsunekazu、Nakanuma Yasuni、Saruta Masayuki、Ochiya Takahiro、Tsubota Akihito
- Journal Title
  
  BMJ Open Gastroenterology
  
  Volume: 9 Issue: 1 Pages: e000879-e000879
- DOI
  10.1136/bmjgast-2022-000879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-18K15798
[Journal Article] Plasma pentosidine levels are associated with prevalent fractures in patients with chronic liver disease.2021
- Author(s)
  Saeki C, Saito M, Kanai T, Nakano M, Oikawa T, Torisu Y, Saruta M, Tsubota A.
- Journal Title
  
  PLoS One
  
  Volume: 16 Issue: 4 Pages: e0249728-e0249728
- DOI
  10.1371/journal.pone.0249728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Influencing Factors and Molecular Pathogenesis of Sarcopenia and Osteosarcopenia in Chronic Liver Disease.2021
- Author(s)
  Saeki C, Tsubota A
- Journal Title
  
  Life (Basel)
  
  Volume: 11 Issue: 9 Pages: 899-899
- DOI
  10.3390/life11090899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Effect of sodium-glucose cotransporter 2 inhibitor in patients with non-alcoholic fatty liver disease and type 2 diabetes mellitus: a propensity score-matched analysis of real-world data.2021
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Mikami S, Ono H, Kawano T, Yoshida Y, Tanabe T, Okubo T, Hayama K, Nakagawa-Iwashita A, Itokawa N, Kondo C, Kaneko K, Emoto N, Nagao M, Inagaki K, Fukuda I, Sugihara H, Iwakiri K.
- Journal Title
  
  Ther Adv Endocrinol Metab
  
  Volume: 12 Pages: 1-13
- DOI
  10.1177/20420188211000243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Clinical Usefulness of FRAX Score for Predicting Sarcopenia in Patients with Chronic Liver Disease.2021
- Author(s)
  Saeki C, Saito M, Kanai T, Nakano M, Oikawa T, Torisu Y, Saruta M, Tsubota A.
- Journal Title
  
  J Clin Med
  
  Volume: 10 Issue: 18 Pages: 4080-4080
- DOI
  10.3390/jcm10184080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Effect of Vitamin D Supplementation on Skeletal Muscle Volume and Strength in Patients with Decompensated Liver Cirrhosis Undergoing Branched Chain Amino Acids Supplementation: A Prospective, Randomized, Controlled Pilot Trial.2021
- Author(s)
  Okubo T, Atsukawa M, Tsubota A, Ono H, Kawano T, Yoshida Y, Arai T, Hayama K, Itokawa N, Kondo C, Kaneko K, Iwakiri K.
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 6 Pages: 1874-1874
- DOI
  10.3390/nu13061874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Real-time breath ammonia measurement using a novel cuprous bromide sensor device in patients with chronic liver disease: a feasibility and pilot study2021
- Author(s)
  Ishida Jinya, Oikawa Tsunekazu, ...., Tsubota Akihito (last; 他11名)
- Journal Title
  
  Journal of Breath Research
  
  Volume: 15 Issue: 2 Pages: 026010-026010
- DOI
  10.1088/1752-7163/abb477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Liver fibrosis is associated with carotid atherosclerosis in patients with liver biopsy-proven nonalcoholic fatty liver disease.2021
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Kato K, Abe H, Ono H, Kawano T, Yoshida Y, Tanabe T, Okubo T, Hayama K, Nakagawa-Iwashita A, Itokawa N, Kondo C, Kaneko K, Emoto N, Nagao M, Inagaki K, Fukuda I, Sugihara H, Iwakiri K.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 15938-15938
- DOI
  10.1038/s41598-021-95581-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Time‐course changes in liver functional reserve after successful sofosbuvir/velpatasvir treatment in patients with decompensated cirrhosis2021
- Author(s)
  Atsukawa Masanori、Watanabe Tsunamasa、Iwakiri Katsuhiko
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 3 Pages: 235-246
- DOI
  10.1111/hepr.13739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-17K09435, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-20K08314
[Journal Article] A novel noninvasive formula for predicting cirrhosis in patients with chronic hepatitis C2021
- Author(s)
  Atsukawa M, Tsubota A, Kondo C, Uchida-Kobayashi S, Takaguchi K, Tsutsui A, Nozaki A, Chuma M, Hidaka I, Ishikawa T, Iwasa M, Tamai Y, Tobari M, Matsuura K, Nagura Y, Abe H, Kato K, Suzuki K, Okubo T, Arai T, Itokawa N, Toyoda H, Enomoto M, Tamori A, Tanaka Y, Kawada N, Takei Y, Iwakiri K.
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 9 Pages: e0257166-e0257166
- DOI
  10.1371/journal.pone.0257166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09435, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-20K08314
[Journal Article] Clinical characteristics of sarcopenia in patients with alcoholic liver cirrhosis.2021
- Author(s)
  Saeki C, Kanai T, Nakano M, Oikawa T, Torisu Y, Saruta M, Tsubota A.
- Journal Title
  
  JGH Open
  
  Volume: 5 Issue: 7 Pages: 12582-12582
- DOI
  10.1002/jgh3.12582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Factors Associated with Hepatitis B Surface Antigen Kinetics and Responses in Pegylated Interferon Alpha-2a Monotherapy for Patients with Chronic Hepatitis B2021
- Author(s)
  Itokawa Norio, Atsukawa Masanori, Tsubota Akihito, et al. (他13名)
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 4 Pages: 507-516
- DOI
  10.2169/internalmedicine.5432-20
- NAID
  130007986439
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-02-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Analysis of factors associated with the prognosis of cirrhotic patients who were treated with tolvaptan for hepatic edema2020
- Author(s)
  Atsukawa M, Tsubota A, Takaguchi K, Toyoda H, Iwasa M, Ikegami T, Chuma M, Nozaki A, Uojima H, Hiraoka A, Fukunishi S, Yokohama K, Tada T, Kato K, Abe H, Tani J, Okubo H, Watanabe T, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: - Issue: 7 Pages: 1229-1237
- DOI
  10.1111/jgh.14965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Low Serum Branched-chain Amino Acid and Insulin-Like Growth Factor-1 Levels Are Associated with Sarcopenia and Slow Gait Speed in Patients with Liver Cirrhosis2020
- Author(s)
  Saeki Chisato、Kanai Tomoya、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 10 Pages: 3239-3239
- DOI
  10.3390/jcm9103239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Relationship between osteoporosis, sarcopenia, vertebral fracture, and osteosarcopenia in patients with primary biliary cholangitis2020
- Author(s)
  Saeki Chisato、Oikawa Tsunekazu、Kanai Tomoya、Nakano Masanori、Torisu Yuichi、Sasaki Nobuyuki、Abo Masahiro、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  European Journal of Gastroenterology & Hepatology
  
  Volume: 33 Issue: 5 Pages: 731-737
- DOI
  10.1097/meg.0000000000001791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-18KK0246
[Journal Article] The effectiveness and safety of glecaprevir/pibrentasvir in chronic hepatitis C patients with refractory factors in the real world: a comprehensive analysis of a prospective multicenter study2020
- Author(s)
  Nozaki, A. Atsukawa, M. Ogawa, S. Itokawa, N. Arai, T. Ikegami, T. Tsubota, A. Genda, T. Okubo, H. Mikami, S. Morishita, A. Moriya, A. Tani, J. Tachi, Y. Hotta, N. Ishikawa, T. Okanoue, T. Tanaka, Y. Kumada, T. Iwakiri, K. Maeda, S. K. T. K. Liver Study Group
- Journal Title
  
  Hepatol Int
  
  Volume: - Issue: 2 Pages: 225-238
- DOI
  10.1007/s12072-020-10019-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Relationship between Osteosarcopenia and Frailty in Patients with Chronic Liver Disease2020
- Author(s)
  Saeki Chisato、Kanai Tomoya、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Abo Masahiro、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 8 Pages: 2381-2381
- DOI
  10.3390/jcm9082381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] IgM response is a prognostic biomarker of primary biliary cholangitis treated with ursodeoxycholic acid and bezafibrate2020
- Author(s)
  Takano Keiko、Saeki Chisato、Oikawa Tsunekazu、Hidaka Akihisa、Mizuno Yusuke、Ishida Jinya、Takakura Kazuki、Nakano Masanori、Torisu Yuichi、Amano Katsushi、Ishikawa Tomohisa、Zeniya Mikio、Tsubota Akihito、Saruta Masayuki
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 35 Issue: 4 Pages: 663-672
- DOI
  10.1111/jgh.14900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Marked heterogeneity in the diagnosis of compensated cirrhosis of patients with chronic hepatitis C virus infection in a real-world setting: A large, multicenter study from Japan2020
- Author(s)
  Toyoda H, Atsukawa M, Watanabe T..., Tsubota A, et al
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Issue: 8 Pages: 1420-1425
- DOI
  10.1111/jgh.14982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-19K08451
[Journal Article] Sequential therapy from entecavir to tenofovir alafenamide versus continuous entecavir monotherapy for patients with chronic hepatitis B2020
- Author(s)
  Itokawa Norio, Atsukawa Masanori, Tsubota Akihito, et al. (他30名)
- Journal Title
  
  JGH Open
  
  Volume: 5 Issue: 1 Pages: 34-40
- DOI
  10.1002/jgh3.12443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Relationship between serum vitamin D level and sarcopenia in chronic liver disease2020
- Author(s)
  Okubo T, Atsukawa M, Tsubota A, Yoshida Y, Arai T, Iwashita AN, Itokawa N, Kondo C, Iwakiri K
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 5 Pages: 588-597
- DOI
  10.1111/hepr.13485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Real-World Clinical Application of 12-Week Sofosbuvir/Velpatasvir Treatment for Decompensated Cirrhotic Patients with Genotype 1 and 2: A Prospective, Multicenter Study2020
- Author(s)
  Atsukawa Masanori、Tsubota Akihito、Kondo Chisa、Toyoda Hidenori、Nakamuta Makoto、Takaguchi Koichi、Watanabe Tsunamasa、et al.
- Journal Title
  
  Infectious Diseases and Therapy
  
  Volume: 9 Issue: 4 Pages: 851-866
- DOI
  10.1007/s40121-020-00329-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Effects of denosumab treatment in chronic liver disease patients with osteoporosis2020
- Author(s)
  Saeki Chisato、Saito Mitsuru、Oikawa Tsunekazu、Nakano Masanori、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 26 Issue: 33 Pages: 4960-4971
- DOI
  10.3748/wjg.v26.i33.4960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Prevalence and characteristics of portopulmonary hypertension in cirrhotic patients who underwent both hepatic vein and pulmonary artery catheterization2020
- Author(s)
  Atsukawa Masanori, Tsubota Akihito, et al. (他20名)
- Journal Title
  
  Hepatology Research
  
  Volume: 50 Issue: 11 Pages: 1244-1254
- DOI
  10.1111/hepr.13560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-19K09160
[Journal Article] Low Serum 25-Hydroxyvitamin D Levels Are Related to Frailty and Sarcopenia in Patients with Chronic Liver Disease2020
- Author(s)
  Saeki Chisato、Kanai Tomoya、Nakano Masanori、Oikawa Tsunekazu、Torisu Yuichi、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 12 Pages: 3810-3810
- DOI
  10.3390/nu12123810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Association of vitamin D levels and vitamin D-related gene polymorphisms with liver fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease.2019
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Koeda M, Yoshida Y, Okubo T, Nakagawa A, Itokawa N, Kondo C, Nakatsuka K, Masu T, Kato K, Shimada N, Hatori T, Emoto N, Kage M, Iwakiri K.
- Journal Title
  
  Dig Liver Dis.
  
  Volume: in press Issue: 7 Pages: 1036-1042
- DOI
  10.1016/j.dld.2018.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08936, KAKENHI-PROJECT-19K08937
[Journal Article] Evaluation of 8‐week glecaprevir/pibrentasvir treatment in direct‐acting antiviral‐naive noncirrhotic HCV genotype 1 and 2 infected patients in a real‐world setting in Japan2019
- Author(s)
  Ikeda H, Watanabe T, Iio E, Tsubota A, Hiraoka A, Nozaki A, Okubo H, Tachi Y, Moriya A, Oikawa T, Matsumoto Y, Tsuruoka S, Tani J, Kikuchi K, Iwakiri K, Tanaka Y, Kumada T, et al.
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 26 Issue: 11 Pages: 1266-1275
- DOI
  10.1111/jvh.13170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Factors influencing subclinical atherosclerosis in patients with biopsy-proven nonalcoholic fatty liver disease2019
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Kawano T, Koeda M, Yoshida Y, Tanabe T, Okubo T, Hayama K, Iwashita A, Itokawa N, Kondo C, Kaneko K, Kawamoto C, Hatori T, Emoto N, Iio E, Tanaka Y, Iwakiri K
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 11 Pages: e0224184-e0224184
- DOI
  10.1371/journal.pone.0224184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C2019
- Author(s)
  Kato K, Shimada N, Atsukawa M, Abe H, Itokawa N, Matsumoto Y, Agata R, Tsubota A
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 7 Pages: e0219022-e0219022
- DOI
  10.1371/journal.pone.0219022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Efficacy and safety of ombitasvir/paritaprevir/ritonavir and ribavirin for chronic hepatitis patients infected with genotype 2a in Japan.2019
- Author(s)
  Atsukawa M, Tsubota A, Toyoda H, Takaguchi K, Nakamuta M, Watanabe T, Tada T, Tsutsui A, Ikeda H, Abe H, Kato K, Uojima H, Ikegami T, Asano T, Kondo C, Koeda M, Okubo T, Arai T, Iwashita-Nakagawa A, Itokawa N, Kumada T, Iwakiri K
- Journal Title
  
  Hepatol Res
  
  Volume: 49 Issue: 4 Pages: 369-376
- DOI
  10.1111/hepr.13292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Comparative assessment of sarcopenia using the JSH, AWGS, and EWGSOP2 criteria and the relationship between sarcopenia, osteoporosis, and osteosarcopenia in patients with liver cirrhosis2019
- Author(s)
  Saeki C, Takano K, Oikawa T, Aoki Y, Kanai T, Takakura K, Nakano M, Torisu Y, Sasaki N, Abo M, Matsuura T, Tsubota A, Saruta M
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 20 Issue: 1 Pages: 615-615
- DOI
  10.1186/s12891-019-2983-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937
[Journal Article] Real‐world experience of 12‐week direct‐acting antiviral regimen of glecaprevir and pibrentasvir in patients with chronic hepatitis C virus infection2019
- Author(s)
  Toyoda H, Atsukawa M, Watanabe T, et al
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: - Issue: 5 Pages: 855-861
- DOI
  10.1111/jgh.14874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-16K09377
[Journal Article] The efficacy and safety of glecaprevir plus pibrentasvir in 141 patients with severe renal impairment: a prospective, multicenter study.2019
- Author(s)
  Atsukawa M, Tsubota A, Toyoda H, Takaguchi K, Nakamuta M, Watanabe T, Michitaka K, Ikegami T, Nozaki A, Uojima H, Fukunishi S, Genda T, Abe H, Hotta N, Tsuji K, Ogawa C, Tachi Y, Shima T, Shimada N, Kondo C, Akahane T, Aizawa Y, Tanaka Y, Kumada T, Iwakiri K
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 49 Issue: 9 Pages: 1230-1241
- DOI
  10.1111/apt.15218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937
[Journal Article] Trends and Efficacy of Interferon-Free Anti-hepatitis C Virus Therapy in the Region of High Prevalence of Elderly Patients, Cirrhosis, and Hepatocellular Carcinoma: A Real-World, Nationwide, Multicenter Study of 10 688 Patients in Japan2019
- Author(s)
  Toyoda H, Atsukawa M, Uojima H, Nozaki A, Tamai H, Takaguchi K, Fujioka S, Nakamuta M, Tada T, Yasuda S, Chuma M, Senoh T, Tsutsui A, Yamashita N, Hiraoka A, Michitaka K, Shima T, Akahane T, Itobayashi E, Watanabe T, et al.
- Journal Title
  
  Open Forum Infectious Diseases
  
  Volume: 6 Issue: 5
- DOI
  10.1093/ofid/ofz185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-16K09377
[Journal Article] Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein more reliably distinguishes liver fibrosis stages in non-alcoholic fatty liver disease than serum Mac-2 binding protein2018
- Author(s)
  Atsukawa Masanori、Tsubota Akihito、Okubo Tomomi、Arai Taeang、Nakagawa Ai、Itokawa Norio、Kondo Chisa、Kato Keizo、Hatori Tsutomu、Hano Hiroshi、Oikawa Tsunekazu、Emoto Naoya、Abe Masanori、Kage Masayoshi、Iwakiri Katsuhiko
- Journal Title
  
  Hepatol Res
  
  Volume: in press Issue: 6 Pages: 424-432
- DOI
  10.1111/hepr.13046
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08936, KAKENHI-PROJECT-15K06810, KAKENHI-PROJECT-18K07911
[Journal Article] Efficacy and safety of ombitasvir/paritaprevir/ritonavir combination therapy for genotype 1b chronic hepatitis C patients complicated with chronic kidney disease2018
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Ikegami T, Shimada N, Kato K, Abe H, Okubo T, Itokawa N, Kondo C, Mikami S, Asano T, Chuganji Y, Matsuzaki Y, Toyoda H, Kumada T, Iio E, Tanaka Y, Iwakiri K.
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 7 Pages: 549-555
- DOI
  10.1111/hepr.13058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Efficacy and safety of ledipasvir/sofosbuvir for genotype 1b chronic hepatitis C patients with moderate renal impairment2018
- Author(s)
  Okubo T, Atsukawa M, Tsubota A, Toyoda H, Shimada N, Abe H, Kato K, Hayama K, Arai T, Nakagawa-Iwashita A, Itokawa N, Kondo C, Kawamoto C, Iio E, Tanaka Y, Kumada T, Iwakiri K.
- Journal Title
  
  Hepatol Int
  
  Volume: 12 Issue: 2 Pages: 133-142
- DOI
  10.1007/s12072-018-9859-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells2018
- Author(s)
  Zhu M, Koibuchi A, Ide H, Morio H, Shibuya M, Kamiichi A, Tsubota A, Anzai N, Akita H, Chiba K, Furihata T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 3 Pages: 440-444
- DOI
  10.1248/bpb.b17-00661
- NAID
  130006407348
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Hepatocellular adenoma in a woman who was undergoing testosterone treatment for gender identity disorder2018
- Author(s)
  Kato K, Abe H, Hanawa N, Fukuzawa J, Matsuo R, Yonezawa T, Itoh S, Sato Y, Ika M, Shimizu S, Endo S, Hano H, Izu A, Sugitani M, Tsubota A
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: Mar 27 Issue: 5 Pages: 401-410
- DOI
  10.1007/s12328-018-0854-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Retreatment with sofosbuvir, ledipasvir, and add-on ribavirin for patients who failed daclatasvir and asunaprevir combination therapy2017
- Author(s)
  Suda G, Ogawa K, Yamamoto Y, Katagiri M, Furuya K, Kumagai K, Konno J, Kimura M, Kawagishi N, Ohara M, Umemura M, Ito J, Izumi T, Nakai M, Sho T, Natsuizaka M, Morikawa K, Tsubota A, Shimada N, Iio E, Tanaka Y, Sakamoto N; NORTE Study Group.
- Journal Title
  
  J Gastroenterol
  
  Volume: 印刷中 Issue: 10 Pages: 1122-1129
- DOI
  10.1007/s00535-017-1328-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-15K06810, KAKENHI-PROJECT-16K15420
[Journal Article] Efficacy of daclatasvir/asunaprevir according to resistance-associated variants in chronic hepatitis C with genotype 12017
- Author(s)
  Iio E, Shimada N, Abe H, Atsukawa M, Yoshizawa K, Takaguchi K, Eguchi Y, Nomura H, Kuramitsu T, Kang JH, Matsui T, Hirashima N, Tsubota A, Kusakabe A, Hasegawa I, Miyaki T, Shinkai N, Fujiwara K, Nojiri S, Tanaka Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: 52 Issue: 1 Pages: 94-103
- DOI
  10.1007/s00535-016-1225-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease2017
- Author(s)
  Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Asano T, Yoshizawa K, Okubo T, Chuganji Y, Aizawa Y, Iio E, Tanaka Y, Iwakiri K.
- Journal Title
  
  Hepatol Res
  
  Volume: 47 Issue: 11 Pages: 1165-1173
- DOI
  10.1111/hepr.12879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Clinical evaluation of sofosbuvir/ledipasvir in chronic hepatitis C genotype 1 with and without prior daclatasvir/asnaprevir therapy.2017
- Author(s)
  Iio E, Shimada N, Takaguchi K, Senoh T, Eguchi Y, Atsukawa M, Tsubota A, Abe H, Kato K, Kusakabe A, Miyaki T, Matsuura K, Matsunami K, Shinkai N, Fujiwara K, Nojiri S, Tanaka Y.
- Journal Title
  
  Hepatol Res.
  
  Volume: 印刷中 Issue: 12 Pages: 1308-1316
- DOI
  10.1111/hepr.12898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461004, KAKENHI-PROJECT-15K06810
[Journal Article] Clinical Significance of Two Real-Time PCR Assays for Chronic Hepatitis C Patients Receiving Protease Inhibitor-Based Therapy2017
- Author(s)
  Inoue T, Hmwe SS, Shimada N, Kato K, Ide T, Torimura T, Kumada T, Toyoda H, Tsubota A, Takaguchi K, Wakita T, Tanaka Y.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 1 Pages: e0170667-e0170667
- DOI
  10.1371/journal.pone.0170667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Effectiveness and safety of community-based treatment with sofosbuvir plus ribavirin for elderly patients with genotype 2 chronic hepatitis C2017
- Author(s)
  Atsukawa M, Tsubota A, Kondo C, Shimada N, Abe H, Kato K, Okubo T, Arai T, Itokawa N, Iio E, Tanaka Y, Iwakiri K.
- Journal Title
  
  Dig Liver Dis
  
  Volume: 49 Issue: 9 Pages: 1029-1035
- DOI
  10.1016/j.dld.2017.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Efficacy and safety of ombitasvir/paritaprevir/ritonavir in dialysis patients with genotype 1b chronic hepatitis C2017
- Author(s)
  Atsukawa M, Tsubota A, Koushima Y, Ikegami T, Watanabe K, Shimada N, Sato S, Kato K, Abe H, Okubo T, Arai T, Itokawa N, Kondo C, Mikami S, Asano T, Chuganji Y, Matsuzaki Y, Iwakiri K.
- Journal Title
  
  Hepatology Research
  
  Volume: 印刷中 Issue: 13 Pages: 1429-1437
- DOI
  10.1111/hepr.12910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-15K06810
[Journal Article] Human organic anion transporter 2 is an entecavir, but not tenofovir, transporter2017
- Author(s)
  Furihata T, Morio H, Zhu M, Suzuki Y, Ide H, Tsubota A, Fu Z, Anzai N, Chiba K.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 32 Issue: 1 Pages: 116-119
- DOI
  10.1016/j.dmpk.2016.09.004
- NAID
  120006776103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Disorders in Hepatic Copper Secretion: Wilson's Disease and Pleomorphic Syndromes2017
- Author(s)
  Lalioti V, Tsubota A, Sandoval IV.
- Journal Title
  
  Semin Liver Dis
  
  Volume: 37 Issue: 02 Pages: 175-188
- DOI
  10.1055/s-0037-1602764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Analysis of factors predicting the response to tolvaptan in patients with liver cirrhosis and hepatic edema2017
- Author(s)
  Atsukawa M, Tsubota A, Kato K, Abe H, Shimada N, Asano T, Ikegami T, Koeda M, Okubo T, Arai T, Nakagawa-Iwashita A, Yoshida Y, Hayama K, Itokawa N, Kondo C, Chuganji Y, Matsuzaki Y, Iwakiri K.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 6 Pages: 1256-1263
- DOI
  10.1111/jgh.14047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] C-Arm Cone Beam Computed Tomography Guidance for Radiofrequency Ablation in Hepatocellular Carcinoma2017
- Author(s)
  Kato K, Abe H, Ika M, Yonezawa T, Sato Y, Hanawa N, Shimizu S, Endo S, Matsuo R, Tsubota A.
- Journal Title
  
  Oncology
  
  Volume: 92 Issue: 3 Pages: 142-152
- DOI
  10.1159/000453665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Usefulness of portal vein pressure for predicting the effects of tolvaptan in cirrhotic patients2016
- Author(s)
  Nakagawa A, Atsukawa M, Tsubota A, Kondo C, Okubo T, Arai T, Itokawa N, Narahara Y, Iwakiri K.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22 Issue: 21 Pages: 5104-13
- DOI
  10.3748/wjg.v22.i21.5104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Single-Nucleotide Resolution Mapping of Hepatitis B Virus Promoters in Infected Human Livers and Hepatocellular Carcinoma2016
- Author(s)
  4.Altinel K, Hashimoto K, Wei Y, Neuveut C, Gupta I, Suzuki AM, Dos Santos A, Moreau P, Xia T, Kojima S, Kato S, Takikawa Y, Hidaka I, Shimizu M, Matsuura T, Tsubota A, Ikeda H, Nagoshi S, Suzuki H, Michel ML, Samuel D, Buendia MA, Faivre J, Carninci P.
- Journal Title
  
  J Virol
  
  Volume: 90 Pages: 10811-22
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Effects of sorafenib combined with low-dose interferon therapy for advanced hepatocellular carcinoma: a pilot study.2016
- Author(s)
  2.Itokawa N, Atsukawa M, Tsubota A, Okubo T, Arai T, Nakagawa A, Kondo C, Iwakiri K.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Evaluation of factors associated with relapse in telaprevir-based triple therapy for chronic hepatitis C.2016
- Author(s)
  1.Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Aizawa Y.
- Journal Title
  
  J Postgrad Med
  
  Volume: 62 Issue: 1 Pages: 20-25
- DOI
  10.4103/0022-3859.173191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Association between vitamin D deficiency and pre-existing resistance-associated hepatitis C virus NS5A variants2016
- Author(s)
  1.Okubo T, Atsukawa M, Tsubota A, Shimada N, Abe H, Yoshizawa K, Arai T, Nakagawa A, Itokawa N, Kondo C, Aizawa Y, Iwakiri K.
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 7 Pages: 641-649
- DOI
  10.1111/hepr.12784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Effect of native vitamin D3 supplementation on refractory chronic hepatitis C patients in simeprevir with pegylated interferon/ribavirin.2016
- Author(s)
  4.Atsukawa M, Tsubota A, Shimada N, Yoshizawa K, Abe H, Asano T, Ohkubo Y, Araki M, Ikegami T, Okubo T, Kondo C, Osada Y, Nakatsuka K, Chuganji Y, Matsuzaki Y, Iwakiri K, Aizawa Y.
- Journal Title
  
  Hepatol Res
  
  Volume: Epub ahead of print Issue: 5 Pages: 450-458
- DOI
  10.1111/hepr.12575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Hepatitis C virus G1b infection decreases the number of small low-density lipoprotein particles2016
- Author(s)
  2.Kinoshita C, Nagano T, Seki N, Tomita Y, Sugita T, Aida Y, Itagaki M, Satoh K, Sutoh S, Abe H, Tsubota A, Aizawa Y.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22 Issue: 29 Pages: 6716-25
- DOI
  10.3748/wjg.v22.i29.6716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Effects of sorafenib combined with low-dose interferon therapy for advanced hepatocellular carcinoma: a pilot study2016
- Author(s)
  3.Itokawa N, Atsukawa M, Tsubota A, Okubo T, Arai T, Nakagawa A, Kondo C, Iwakiri K.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 21 Issue: 4 Pages: 676-83
- DOI
  10.1007/s10147-015-0942-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Impact of Chronic Hepatitis C Virus Genotype 1b Infection on Triglyceride Concentration in Serum Lipoprotein Fractions.2015
- Author(s)
  3.Nagano T, Seki N, Tomita Y, Sugita T, Aida Y, Itagaki M, Sutoh S, Abe H, Tsubota A, Aizawa Y.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 16 Issue: 9 Pages: 20576-20594
- DOI
  10.3390/ijms160920576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Safety and Efficacy of Partial Splenic Embolization in Telaprevir-based Triple Therapy for Chronic Hepatitis C2015
- Author(s)
  Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Itokawa N, Nakagawa A, Fukuda T, Matsushita Y, Nakatsuka K, Kawamoto C, Iwakiri K, Aizawa Y, Sakamoto C.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 2 Pages: 119-126
- DOI
  10.2169/internalmedicine.54.3066
- NAID
  130004903010
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-15K06810
[Journal Article] Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1.2015
- Author(s)
  Furihata T, Fu Z, Suzuki Y, Matsumoto S, Morio H, Tsubota A, Matsumoto S, Chiba K.
- Journal Title
  
  Int J Antimicrob Agents
  
  Volume: 46 Issue: 4 Pages: 381-388
- DOI
  10.1016/j.ijantimicag.2015.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Influencing factors on serum 25-hydroxyvitamin D3 levels in Japanese chronic hepatitis C patients.2015
- Author(s)
  Atsukawa M, Tsubota A, Shimada N, Yoshizawa K, Abe H, Asano T, Ohkubo Y, Araki M, Ikegami T, Kondo C, Itokawa N, Nakagawa A, Arai T, Matsushita Y, Nakatsuka K, Furihata T, Chuganji Y, Matsuzaki Y, Aizawa Y, Iwakiri K.
- Journal Title
  
  BMC Infect Dis
  
  Volume: 15 Issue: 1 Pages: 344-344
- DOI
  10.1186/s12879-015-1020-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Factors associated with sustained virological response in 24-week telaprevir-based triple therapy for chronic hepatitis C genotype 1b patients with the IL28B minor genotype2015
- Author(s)
  Abe H, Tsubota A, Shimada N, Atsukawa M, Kato K, Takaguchi K, Asano T, Chuganji Y, Sakamoto C, Toyoda H, Kumada T, Ide T, Sata M, Aizawa Y.
- Journal Title
  
  Hepatol Res
  
  Volume: 45 Issue: 4 Pages: 387-36
- DOI
  10.1111/hepr.12360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-15K06810
[Journal Article] Vitamin D-related gene polymorphisms do not influence the outcome and serum vitamin D level in pegylated interferon/ribavirin therapy combined with protease inhibitor for patients with genotype 1b chronic hepatitis C.2015
- Author(s)
  Arai T, Atsukawa M, Tsubota A, Kondo C, Shimada N, Abe H, Itokawa N, Nakagawa A, Okubo T, Aizawa Y, Iwakiri K.
- Journal Title
  
  J Med Virol
  
  Volume: 87 Issue: 11 Pages: 1904-1912
- DOI
  10.1002/jmv.24244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Interferon-λ3 polymorphisms in pegylated-interferon-α plus ribavirin therapy for genotype-2 chronic hepatitis C.2015
- Author(s)
  Ishiguro H, Abe H, Seki N, Sugita T, Aida Y, Itagaki M, Sutoh S, Shimada N, Furihata T, Tsubota A, Aizawa Y.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 21 Issue: 13 Pages: 3904-3911
- DOI
  10.3748/wjg.v21.i13.3904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06810
[Journal Article] Predictors of response to 24-week telaprevir-based triple therapy for treatment-naïve genotype 1b chronic hepatitis C patients2014
- Author(s)
  Abe H, Tsubota A, Shimada N, Atsukawa M, Kato K, Takaguchi K, Asano T, Chuganji Y, Sakamoto C, Toyoda H, Kumada T, Ide T, Sata M, Aizawa Y.
- Journal Title
  
  Gastroenterol Res Pract
  
  Volume: 2014 Pages: 549709-549709
- DOI
  10.1155/2014/549709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Effect of fluvastatin on 24-week telaprevir-based combination therapy for hepatitis C virus genotype 1b-infected chronic hepatitis C2014
- Author(s)
  Atsukawa M, Tsubota A, Shimada N, Kondo C, Itokawa N, Nakagawa A, Fukuda T, Matsushita Y, Narahara Y, Osada Y, Yamaguchi H, Nakatsuka K, Iwakiri K, Kawamoto C, Sakamoto C.
- Journal Title
  
  Eur J Gastroenterol Hepatol
  
  Volume: 26 Issue: 7 Pages: 781-787
- DOI
  10.1097/meg.0000000000000105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Impact of IL28B polymorphisms on 24-week telaprevir-based combination therapy for Asian chronic hepatitis C patients with hepatitis C virus genotype 1b.2014
- Author(s)
  Tsubota A, Shimada N, Atsukawa M, Abe H, Kato K, Ika M, Matsudaira H, Nagatsuma K, Matsuura T, Aizawa Y.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 1 Pages: 144-150
- DOI
  10.1111/jgh.12402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] α-Fetoprotein is a surrogate marker for predicting treatment failure in telaprevir-based triple combination therapy for genotype 1b chronic hepatitis C Japanese patients with the IL28B minor genotype.2014
- Author(s)
  Shimada N, Tsubota A, Atsukawa M, Abe H, Ika M, Kato K, Sato Y, Kondo C, Sakamoto C, Tanaka Y, Aizawa Y.
- Journal Title
  
  J Med Virol
  
  Volume: 86 Issue: 3 Pages: 461-472
- DOI
  10.1002/jmv.23824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] A 48-week telaprevir-based triple combination therapy improves sustained virological response rate in previous non-responders to peginterferon and ribavirin with genotype 1b chronic hepatitis C: A multicenter study.2014
- Author(s)
  Shimada N, Tsubota A, Atsukawa M, Abe H, Ide T, Takaguchi K, Chuganji Y, Toyoda H, Yoshizawa K, Ika M, Sato Y, Kato K, Kumada T, Sakamoto C, Aizawa Y, Sata M.
- Journal Title
  
  Hepatol Res
  
  Volume: 2014 Mar (Epub ahead of print) Issue: 14
- DOI
  10.1111/hepr.12323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Baseline factors and very early viral response (week 1) for predicting sustained virological response in telaprevir-based triple combination therapy for Japanese genotype 1b chronic hepatitis C patients: a multicenter study2014
- Author(s)
  Shimada N, Toyoda H, Tsubota A, Ide T, Takaguchi K, Kato K, Kondoh M, Matsuyama K, Kumada T, Sata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 49 Issue: 11 Pages: 1485-1494
- DOI
  10.1007/s00535-013-0918-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Different interaction profiles of direct-acting anti-hepatitis C virus agents with human organic anion transporting polypeptides2014
- Author(s)
  Furihata T, Matsumoto S, Fu Z, Tsubota A, Sun Y, Matsumoto S, Kobayashi K, Chiba K.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 58 Issue: 8 Pages: 4555-4564
- DOI
  10.1128/aac.02724-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Hepatic stellate cells that coexpress LRAT and CRBP-1 partially contribute to portal fibrogenesis in patients with human viral hepatitis.2014
- Author(s)
  Nagatsuma K, Hano H, Murakami K, Shindo D, Matsumoto Y, Mitobe J, Tanaka K, Saito M, Maehashi H, Owada M, Ikegami M, Tsubota A, Ohkusa T, Aizawa Y, Takagi I, Tajiri H, Matsuura T.
- Journal Title
  
  Liver Int
  
  Volume: 34 Issue: 2 Pages: 243-252
- DOI
  10.1111/liv.12255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Relationship between HCV dynamics and sustained virological responses in chronic hepatitis C genotype 1b patients treated with telaprevir-based triple therapy2014
- Author(s)
  Nakagawa A, Atsukawa M, Tsubota A, Shimada N, Abe H, Kondo C, Itokawa N, Arai T, Hashimoto S, Matsushita Y, Fukuda T, Nakatsuka K, Iwakiri K, Kawamoto C, Aizawa Y, Sakamoto C.
- Journal Title
  
  Eur J Gastroenterol Hepatol
  
  Volume: 26 Issue: 12 Pages: 1329-1334
- DOI
  10.1097/meg.0000000000000228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Serum 25(OH)D3 levels affect treatment outcomes for telaprevir/peg-interferon/ribavirin combination therapy in genotype 1b chronic hepatitis C2014
- Author(s)
  Atsukawa M, Tsubota A, Shimada N, Abe H, Kondo C, Itokawa N, Nakagawa A, Iwakiri K, Kawamoto C, Aizawa Y, Sakamoto C.
- Journal Title
  
  Dig Liver Dis
  
  Volume: 46 Issue: 8 Pages: 738-743
- DOI
  10.1016/j.dld.2014.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Serum 25-hydroxy- vitamin D3 levels affect treatment outcome in pegylated-interferon/ ribavirin combination therapy for compensated cirrhotic patients with HCV genotype 1b and high viral load.2014
- Author(s)
  Atsukawa M, Tsubota A, Shimada N, Kondo C, Itokawa N, Nakagawa A, Hashimoto S, Fukuda T, Matsushita Y, Narahara Y, Iwakiri K, Nakatsuka K, Kawamoto C, Sakamoto C.
- Journal Title
  
  Hepatol Res
  
  Volume: 2014 Jan (Epub ahead of print) Issue: 13 Pages: 1277-1285
- DOI
  10.1111/hepr.12298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C2014
- Author(s)
  Tsubota A, Mogushi K, Aizaki H, Miyaguchi K, Nagatsuma K, Matsudaira H, Kushida T, Furihata T, Tanaka H, Matsuura T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 5 Pages: e97078-e97078
- DOI
  10.1371/journal.pone.0097078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-26870175
[Journal Article] Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C2014
- Author(s)
  Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Komatsu M, Masaki T, Enomoto N, Yoneda M, Murata K, Ito K, Koike K, Mizokami M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 12 Pages: 1996-2005
- DOI
  10.1111/jgh.12646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25461014
[Journal Article] Risk factors for long-term persistence of serum hepatitis B surface antigen following acute hepatitis B virus infection in Japanese adults2014
- Author(s)
  Ito K, Yotsuyanagi H, Yatsuhashi H, Karino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Maeshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami M; Japanese AHB Study Group
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 1 Pages: 89-97
- DOI
  10.1002/hep.26635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25860574
[Journal Article] Baseline factors and very early viral response (week 1) for predicting sustained virological response in telaprevir-based triple combination therapy for Japanese genotype 1b chronic hepatitis C patients: a multicenter study.2013
- Author(s)
  Shimada N, Toyoda H, Tsubota A, Ide T, Takaguchi K, Kato K, Kondoh M, Matsuyama K, Kumada T, Sata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 2013 Nov (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Sustained and rapid virological responses in hepatitis C clinical trials.2013
- Author(s)
  Tsubota A, Furihata T, Matsumoto Y, Chiba K.
- Journal Title
  
  Clinical Investigation
  
  Volume: 3 Issue: 11 Pages: 1083-1093
- DOI
  10.4155/cli.13.98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Serum lipoprotein profiles and response to pegylated interferon plus ribavirin combination therapy in patients with chronic HCV genotype 1b infection.2013
- Author(s)
  Aizawa Y, Shimada N, Abe H, Seki N, Aida Y, Ishiguro H, Ika M, Kato K, Tsubota A.
- Journal Title
  
  Hepat Mon
  
  Volume: 13 Issue: 5
- DOI
  10.5812/hepatmon.8988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Serum apolipoprotein B-100 concentration predicts the virological response to pegylated interferon plus ribavirin combination therapy in patients infected with chronic hepatitis C virus genotype 1b.2013
- Author(s)
  Yoshizawa K, Abe H, Aida Y, Ishiguro H, Ika M, Shimada N, Tsubota A, Aizawa Y.
- Journal Title
  
  J Med Virol
  
  Volume: 85 Issue: 7 Pages: 1180-1190
- DOI
  10.1002/jmv.23597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Peginterferon Alfa-2a plus ribavirin in Japanese patients infected with hepatitis C virus genotype 2 who failed previous interferon therapy.2013
- Author(s)
  Kanda T, Nakamoto S, Nishino T, Takada N, Tsubota A, Kato K, Miyamura T, Maruoka D, Wu S, Tanaka T, Arai M, Mikami S, Fujiwara K, Imazeki F, Yokosuka O.
- Journal Title
  
  Int J Med Sci
  
  Volume: 10 Issue: 1 Pages: 43-49
- DOI
  10.7150/ijms.5358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24701002, KAKENHI-PROJECT-24790678
[Journal Article] Combination of fluvastatin with pegylated interferon/ribavirin therapy reduces viral relapse in chronic hepatitis C infected with HCV genotype 1b.2013
- Author(s)
  Atsukawa M, Tsubota A, Kondo C, Itokawa N, Narahara Y, Nakatsuka K, Hashimoto S, Fukuda T, Matsushita Y, Kidokoro H, Kobayashi T, Kanazawa H, Sakamoto C.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Issue: 1 Pages: 51-56
- DOI
  10.1111/j.1440-1746.2012.07267.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] New proposal for response-guided peg-interferon-plus- ribavirin combination therapy for chronic hepatitis C virus genotype 2 infection.2013
- Author(s)
  Abe H, Aida Y, Ishiguro H, Yoshizawa K, Seki N, Miyazaki T, Itagaki M, Sutoh S, Ika M, Kato K, Shimada N, Tsubota A, Aizawa Y.
- Journal Title
  
  J Med Virol
  
  Volume: 85 Issue: 9 Pages: 1523-1533
- DOI
  10.1002/jmv.23626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Efficacy of alfacalcidol on PEG-IFN/ribavirin combination therapy for elderly patients with chronic hepatitis C: a pilot study.2013
- Author(s)
  Atsukawa M, Tsubota A, Shimada N, Kondo C, Itokawa N, Nakagawa A, Hashimoto S, Fukuda T, Matsushita Y, Kidokoro H, Narahara Y, Nakatsuka K, Iwakiri K, Kawamoto C, Sakamoto C.
- Journal Title
  
  Hepat Mon
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Lead-in treatment with interferon-β/ribavirin may modify the early hepatitis C virus dynamics in pegylated interferon alpha-2b/ribavirin combination for chronic hepatitis C patients with the IL28B minor genotype.2013
- Author(s)
  Itokawa N, Atsukawa M, Tsubota A, Kondo C, Hashimoto S, Fukuda T, Matsushita Y, Kidokoro H, Kobayashi T, Narahara Y, Nakatsuka K, Kanazawa H, Iwakiri K, Sakamoto C.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Issue: 3 Pages: 443-449
- DOI
  10.1111/jgh.12039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Platelet count and sustained virological response in hepatitis C treatment.2013
- Author(s)
  Kanda T, Kato K, Tsubota A, Takada N, Nishino T, Mikami S, Miyamura T, Maruoka D, Wu S, Nakamoto S, Arai M, Fujiwara K, Imazeki F, Yokosuka O.
- Journal Title
  
  World J Hepatol
  
  Volume: 5 Issue: 4 Pages: 182-188
- DOI
  10.4254/wjh.v5.i4.182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Contribution of ribavirin transporter gene polymorphism to treatment response in peginterferon plus ribavirin therapy for HCV genotype 1b patients.2012
- Author(s)
  Tsubota A, Shimada N, Yoshizawa K, Furihata T, Agata R, Yumoto Y, Abe H, Ika M, Namiki Y, Chiba K, Fujise K, Tada N, Aizawa Y.
- Journal Title
  
  Liver Int
  
  Volume: 32 Issue: 5 Pages: 826-836
- DOI
  10.1111/j.1478-3231.2011.02727.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Several factors including ITPA polymorphism influence ribavirin-induced anemia in chronic hepatitis C.2012
- Author(s)
  Tsubota A, Shimada N, Abe H, Yoshizawa K, Agata R, Yumoto Y, Ika M, Namiki Y, Nagatsuma K, Matsudaira H, Fujise K, Tada N, Aizawa Y.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18 Issue: 41 Pages: 5879-5888
- DOI
  10.3748/wjg.v18.i41.5879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] ENT1, a ribavirin transporter, plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system2012
- Author(s)
  Iikura M, Furihata T, Mizuguchi M, Nagai M, Ikeda M, Kato N, Tsubota A, Chiba K.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 56 Pages: 1407-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] An open-label randomized controlled study of pegylated interferon/ribavirin combination therapy for chronic hepatitis C with versus without fluvastatin.2012
- Author(s)
  Kondo C, Atsukawa M, Tsubota A, Itokawa N, Fukuda T, Matsushita Y, Kidokoro H, Kobayashi T, Narahara Y, Nakatsuka K, Kanazawa H, Sakamoto C.
- Journal Title
  
  J Viral Hepat
  
  Volume: 19 Issue: 9 Pages: 615-622
- DOI
  10.1111/j.1365-2893.2011.01584.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C.2012
- Author(s)
  Aizawa Y, Yohizawa K, Aida Y, Ishiguro H, Abe H, Tsubota A.
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 360 Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Inorganic-Organic Magnetic Nanocomposites for use in Preventive Medicine: A Rapid and Reliable Elimination System for Cesium.2012
- Author(s)
  Namiki Y, Namiki T, Ishii Y, Koido S, Nagase Y, Tsubota A, Tada N, Kitamoto Y.
- Journal Title
  
  Pharm Res
  
  Volume: 29 Issue: 5 Pages: 1404-1418
- DOI
  10.1007/s11095-011-0628-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Occurrence of hepatocellular carcinoma was not a rare event during and immediately after antiviral treatment in Japanese HCV-positive patients.2011
- Author(s)
  Kanda T, Imazeki F, Mikami S, Kato K, Shimada N, Yonemitsu Y, Miyauchi T, Arai M, Fujiwara K, Tsubota A, Takada N, Nishino T, Takashi M, Sugiura N, Kimura M, Fukai K, Yokosuka O.
- Journal Title
  
  Oncology
  
  Volume: 80 Pages: 366-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Clinical course and predictive factors of virological response in long-term lamivudine plus adefovir dipivoxil combination therapy for lamivudine-resistant chronic hepatitis B patients.2011
- Author(s)
  Aizawa M, Tsubota A, Fujise K, Tatsuzawa K, Kono M, Hoshina S, Tajiri H.
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 6 Pages: 953-61
- DOI
  10.1002/jmv.22025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Journal Article] Quantification of hepatitis C virus in patients treated with peginterferon-alfa 2a plus ribavirin treatment by COBAS TaqMan HCV test.2011
- Author(s)
  Kanda T, Imazeki F, Yonemitsu Y, Mikami S, Takada N, Nishino T, Takashi M, Tsubota A, Kato K, Tanaka T, Nakamoto S, Kurihara T, Arai M, Fujiwara K, Kanai F, Yokosuka O.
- Journal Title
  
  J Viral Hepat
  
  Volume: 18 Issue: 7 Pages: 292-7
- DOI
  10.1111/j.1365-2893.2010.01409.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] B型肝炎ウイルスゲノム挿入の新規検出技術開発と肝がん再発予測への応用2023
- Author(s)
  深野顕人,若江亨祥,直亨則,斎藤益満,豊嶋孝恵,坪田昭人,相崎英樹,松平崇弘,木村基,渡士幸一,杉浦亙,村松正道
- Organizer
  第31回日本抗ウイルス療法学会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] Development of prognostic markers for hepatocellular carcinoma using a novel detection method for hepatitis B virus DNA integration2023
- Author(s)
  深野顕人,若江亨祥,直亨則,斎藤益満,豊嶋孝恵,坪田昭人,相崎英樹,松平崇弘,木村基,渡士幸一,杉浦亙,村松正道
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] Hepatocellular organelle and gene expression abnormalities following elimination of hepatitis C virus and carcinogenesis2023
- Author(s)
  青柳東代,飯島尋子,松田麻未,若江亨祥,渡士幸一,鈴木亮介,政木隆博,杉山真也,坪田昭人,島田紀朋,加藤慶三,林和彦,榎本大,酒巻有里子,市野瀬志津子,村松正道,溝上雅史,和氣健二郎,脇田隆字,相崎英樹
- Organizer
  The 3rd JSH International Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] B型肝炎ウイルスゲノム挿入の新規検出技術を応用した肝がん再発予測マーカーの開発2023
- Author(s)
  深野顕人,若江亨祥,直亨則,斎藤益満,豊嶋孝恵,坪田昭人,相崎英樹,松平崇弘,木村基,渡士幸一,杉浦亙,村松正道
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 血清PKCδは既存マーカーを補完し、かつ早期発見に有用な肝細胞癌特異的バイオマーカーである2023
- Author(s)
  及川恒一, 猿田雅之, 坪田昭人
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08063
[Presentation] C型肝炎ウイルス除去後のオルガネラ、遺伝子発現異常と発癌2023
- Author(s)
  青柳東代,飯島尋子,松田麻未,若江亨祥,渡士幸一,鈴木亮介,政木隆博,杉山真也,坪田昭人,島田紀朋,加藤慶三,林和彦,榎本大,酒巻有里子,市野瀬志津子,村松正道,溝上雅史,和氣健二郎,脇田隆字,相崎英樹
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] HBV産生細胞を用いたB型肝炎創薬のための動物モデルの構築と応用2023
- Author(s)
  楊光,青柳東代,若江亨祥,直亨則,坪田昭人,相崎英樹,渡士幸一,村松正道
- Organizer
  第31回日本抗ウイルス療法学会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 血清PKCδは既存マーカーを補完し、かつ早期診断に有用な肝細胞癌特異的バイオマーカーである2023
- Author(s)
  及川恒一,猿田雅之,坪田昭人
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 肝細胞癌のラジオ波熱凝固療法の治療支援としてのCone-beam CTの有用性2022
- Author(s)
  加藤慶三, 安部宏, 坪田昭人.
- Organizer
  第16回肝癌治療ナビゲーション研究会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 実臨床におけるC型非代償性肝硬変患者のDAA治療後の転帰の特徴2022
- Author(s)
  厚川正則, 坪田昭人, 岩切勝彦.
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 等温増幅SmartAmp法を用いたHBV genotype判別法の開発2022
- Author(s)
  古谷裕, Delobel D, 臼井健, 松浦知和, 坪田昭人, 越智小枝.
- Organizer
  第69回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] Cone-beam CTを肝細胞癌のラジオ波熱凝固療法の治療支援としたバルーン閉塞下肝動脈化学塞栓療法併用ラジオ波凝固療法の成績2022
- Author(s)
  加藤慶三, 安部宏, 坪田昭人.
- Organizer
  第44回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 肝細胞癌のラジオ波熱凝固療法の治療支援としてのCone-beam CTの有用性2022
- Author(s)
  加藤慶三, 安部宏, 坪田昭人.
- Organizer
  第16回肝癌治療ナビゲーション研究会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 新規肝細胞癌バイオマーカーとしての血清PKCδの有用性2022
- Author(s)
  及川恒一, 猿田雅之, 坪田昭人.
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 新規肝細胞癌バイオマーカーとしての血清PKCδの有用性2022
- Author(s)
  及川恒一, 猿田雅之, 坪田昭人
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08063
[Presentation] 肝細胞癌における新規バイオマーカー PKC deltaの有用性2022
- Author(s)
  及川恒一, 上田薫, 中川千夏, 神岡洋, 中野真範, 佐伯千里, 鳥巣勇一, 猿田雅之, 坪田昭人.
- Organizer
  第12回首都圏Liver Forum
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 新規肝細胞癌バイオマーカーとしての血清PKCδの有用性2022
- Author(s)
  及川恒一, 猿田雅之, 坪田昭人.
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] Cone-beam CTを肝細胞癌のラジオ波熱凝固療法の治療支援としたバルーン閉塞下肝動脈化学塞栓療法併用ラジオ波凝固療法の成績2022
- Author(s)
  加藤慶三, 安部宏, 坪田昭人.
- Organizer
  第44回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 肝細胞癌における新規バイオマーカー PKC deltaの有用性2022
- Author(s)
  及川恒一, 上田薫, 中川千夏, 神岡洋, 中野真範, 佐伯千里, 鳥巣勇一, 猿田雅之, 坪田昭人.
- Organizer
  第12回首都圏Liver Forum
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 等温増幅SmartAmp法を用いたHBV genotype判別法の開発2022
- Author(s)
  古谷裕, Delobel D, 臼井健, 松浦知和, 坪田昭人, 越智小枝.
- Organizer
  第69回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 実臨床におけるC型非代償性肝硬変患者のDAA治療後の転帰の特徴2022
- Author(s)
  厚川正則, 坪田昭人, 岩切勝彦.
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K08587
[Presentation] 口頭 (Workshop 27: 消化器疾患とサルコペニア：診断, 治療と予後): 肝硬変におけるオステオサルコペニアの重要性.2021
- Author(s)
  佐伯千里, 猿田雅之, 坪田昭人.
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 口頭 (Panel Discussion 1：肝疾患におけるサルコペニアの診断と治療): 肝硬変における血清BCAA, IGF-1とサルコペニアの関連性.2021
- Author(s)
  佐伯千里, 猿田雅之, 坪田昭人.
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 口頭 (O16): 肝性浮腫に対するtolvaptan導入例におけるDAA治療が与える影響.2021
- Author(s)
  北村倫香,厚川正則,豊田秀徳,高口浩一,中牟田誠,渡邊綱正,坪田昭人,熊田卓,河野惟道,田邊智英,新井泰央,糸川典夫,金子恵子,岩切勝彦.
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 高HN3血症早期発見を見据えたリアルタイム呼気NH3濃度測定の有用性の検討2020
- Author(s)
  及川恒一, 石田仁也, 中川千夏, 上田薫, 中野真範, 佐伯千里, 鳥巣勇一, 猿田雅之, 坪田昭人
- Organizer
  第106回日本消化器病学会総会 (JDDW2020)
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 肝細胞癌に対する薬剤溶出性ビーズを用いた肝動脈化学塞栓術の治療経験2020
- Author(s)
  加藤慶三, 安部宏, 井家麻紀子, 坂本雄飛, 清水晶平, 遠藤慎治, 松尾亮太, 坪田昭人
- Organizer
  第43回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] テノホビル・アラフェナミド療法の新規導入における実臨床成績の検討2020
- Author(s)
  糸川典夫, 厚川正則, 坪田昭人
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] NAFLD患者のvitamin D代謝の特徴～vitamin D介入試験の結果も含めて～2019
- Author(s)
  河野惟道, 厚川正則, 肥田舞, 吉田祐士, 大久保知美, 新井泰央, 岩下愛, 糸川典夫, 近藤千紗, 加藤慶三, 島田紀朋, 坪田昭人, 岩切勝彦
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 当院におけるHIV/HCV重複感染例に対するDAA治療2019
- Author(s)
  中野真範, 及川恒一, 木下勇次, 木下千夏, 富田陽一, 高野啓子, 石田仁也, 高倉一樹, 鳥巣勇一, 石川智久, 猿田雅之, 坪田昭人, 李広烈, 保科斉生, 清水昭宏, 吉田正樹, 堀誠治
- Organizer
  第61回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] 肝性脳症に対するrifaximin使用例の予後の検討2019
- Author(s)
  加藤慶三, 安部宏, 坪田昭人
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] Efficacy and safety of glecaprevir/pibrentasvir in patients with severe renal impairment in Japan: A prospective, multicenter study (KTK 49 Liver Study Group)2019
- Author(s)
  Atsukawa M, Tsubota A, Toyoda H, et al
- Organizer
  European Association for the Study of the Liver (EASL) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] C型肝炎に対するダクラタスビル・アスナプレビルの肝障害に関連する遺伝子多型の検討2019
- Author(s)
  加藤慶三, 安部宏, 厚川正則, 島田紀朋, 井家麻紀子, 清水晶平, 塙紀子, 米澤健, 遠藤慎治, 松尾亮太, 坪田昭人
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08937
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis C patients who achieve a sustained virological response2017
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, Takuma Zaitsu, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Ayako Mimata, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Takaji Wakita, Hideki Aizaki
- Organizer
  APASL 2017 (26th)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Abnormal Hepatocellular Organelles Remain to be Observed in Sustained Virological Response Patients2017
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, Takuma Zaitsu, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Akihito Tsubota, Mimata Ayako, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Takaji Wakita, Hideki Aizaki
- Organizer
  APASL Single Topic Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] SVR後の肝臓のオルガネラ異常の解析2017
- Author(s)
  青柳東代, 飯島尋子, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, 在津拓馬, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 島田紀朋, 加藤慶三, 坪田昭人, 三又絢子, 酒巻有里子, 市野瀬志津子, 和氣健二郎, 脇田隆字, 相崎英樹.
- Organizer
  第27回抗ウイルス療法学会総会
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis C patients who achieve a sustained virological response2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Xin Z, Kao YT, Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  APASL 2017 (The 26th Conference of Asian Pacific Association for the Study of the Liver)
- Place of Presentation
  Beijing, China
- Year and Date
  2017-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Xin Z, Kao Y-T, Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Aizawa N, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] A novel device for estimating olfactory threshold for differential diagnosis of parkinsonian syndrome: a pilot study2017
- Author(s)
  Omoto S, Mori E, Fujioka K, Tsubota A, Kita J, Kinoshita M, Matsuno H, Sakai K, Toyoda C, Iguchi Y
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Genotype１C型慢性肝疾患に対するダクラタスビル・アスナプレビルの初期治療反応と抗ウイルス効果の関係2016
- Author(s)
  加藤慶三, 安部宏, 井家麻紀子, 清水晶平, 佐藤祥之, 望月司, 塙紀子, 米澤健, 遠藤慎治, 松尾亮太, 坪田昭人
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張/東京ベイ幕張ホール（千葉）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Ultrastructure of liver cells in chronic hepatitis C patients who achieve a sustained virological response2016
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Xin Z, Kao YT, Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The 15th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji, Japan
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Efficacy of daclatasvir/asunaprevir for chronic hepatitis C patients with renal insufficiency2016
- Author(s)
  Kondo C, Atsukawa M, Shimada N, Tsubota A, Abe H, Okubo T, Nakagawa A, Arai T, Itokawa N, Tanaka Y, Aizawa Y, Iwakiri K
- Organizer
  APASL (2016 in Tokyo, 25th Conference)
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2016-02-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代, 飯島尋子, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 坪田昭人, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第41回日本肝臓学会東部会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代, 飯島尋子, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 酒巻有里子, 市野瀬志津子, 坪田昭人, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第12回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  ホテルグランヴィア広島（広島）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型肝炎ウイルス治療後ウイルス学的著効症例の肝細胞の超微細構造の観察2016
- Author(s)
  相崎英樹, 飯島尋子, 青柳東代, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 藤井さやか, 會澤信弘, 三又絢子, 酒巻有里子, 市野瀬志津子, 坪田昭人, 和氣健二郎, 脇田隆字
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪）
- Year and Date
  2016-07-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] 実臨床におけるGenotype 2のC型慢性肝炎患者に対するソホスブビル, リバビリン併用療法の治療成績2016
- Author(s)
  近藤千紗, 厚川正則, 島田紀朋, 加藤慶三, 安部宏, 大久保知美, 新井泰央, 中川愛, 糸川典夫, 坪田昭人, 相澤良夫, 岩切勝彦
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張/東京ベイ幕張ホール（千葉）
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝炎における背景因子の特徴による薬剤選択2016
- Author(s)
  厚川正則, 島田紀朋, 大久保知美, 安部宏, 加藤慶三, 三上繁, 坪田昭人, 池上正, 中願寺義通, 岩切勝彦
- Organizer
  第20回日本肝臓学会大会
- Place of Presentation
  神戸コンベンションセンター（神戸）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Serum 25(OH)D3 levels are related to the severity of liver fibrosis in patients with NAFLD2016
- Author(s)
  Arai T, Atsukawa M, Kondo C, Itokawa N, Nakagawa A, Okubo T, Kato K, Tsubota A, Iwakiri K
- Organizer
  APASL (2016 in Tokyo, 25th Conference)
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代, 飯島尋子, 渡士幸一, 鈴木亮介, 政木隆博, 坂巻有里子, 市野瀬志津子, 坪田昭人, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋市立大学（名古屋）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Efficacy and safety of ombitasvir/ritonavir/paritaprevir combination therapy for genotype 1b chronic hepatitis C patients complicated with chronic kidney disease2016
- Author(s)
  Arai T, Atsukawa M, Ikegami T, Mikami S, Shimada N, Tsubota A, Kato K, Abe H, Okubo T, Nakagawa A, Itokawa N, Kondo C, Iwakiri K
- Organizer
  AASLD 2016 (The Liver Meeting, the 67th Conference of American Association for the Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] 本邦におけるNAFLD患者と血清ビタミンD代謝2016
- Author(s)
  新井泰央, 厚川正則, 大久保知美, 中川愛, 糸川典夫, 近藤千紗, 加藤慶三, 坪田昭人, 岩切勝彦
- Organizer
  第20回日本肝臓学会大会
- Place of Presentation
  神戸コンベンションセンター（神戸）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] DCV+ASV併用療法の薬剤耐性変異別の治療効果及びAFPの推移2015
- Author(s)
  島田紀朋,厚川正則,安部宏,吉澤海,田中靖人,坪田昭人,相澤良夫
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] 治療開始4週後のHCV RNA量から見たSMV3剤併用療法の治療効果予測2015
- Author(s)
  島田紀朋,厚川正則,安部宏,吉澤海,高口浩一,石川達,辻邦彦,熊田卓,飯尾悦子,田中靖人,平岡淳,坪田昭人,相澤良夫
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] SMV3剤併用療法の難治要因の検討2015
- Author(s)
  島田紀朋,厚川正則,田中靖人,坪田昭人
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] Genotype 1b C型慢性肝炎に対するSimeprevir+Peginterferon+Ribavirin３剤療法の早期治療効果2015
- Author(s)
  杉田知典,安部宏,富田陽一,永野智久,関伸嘉,会田雄太,板垣宗徳,須藤訓,坪田昭人,相澤良夫
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] 肝硬変に伴う腹水に対するトルバプタンの治療成績2015
- Author(s)
  加藤慶三,塙紀子,米澤健,佐藤祥之,井家麻紀子,清水昌平,松尾亮太,坪田昭人
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  鶴屋東館（熊本）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝炎に対するDCV/ASV療法の成績に与える因子の解析2015
- Author(s)
  厚川正則,島田紀朋,吉澤海,安部宏,大久保知美,新井康央,中川愛,糸川典夫,近藤千紗,坪田昭人,相澤良夫,岩切勝彦
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝炎治療におけるvitamin Dの影響～vitamin D併用SMV３剤併用療法RCTから得られた知見～2015
- Author(s)
  厚川正則,島田紀朋,坪田昭人
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] IFN反応性とウイルス変異から見た治療戦略2015
- Author(s)
  島田紀朋,厚川正則,坪田昭人
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] DAAsに対するNS5A領域の薬剤耐性変異を有する症例の特徴2015
- Author(s)
  大久保知美,厚川正則,島田紀朋,安部宏,吉澤海,新井康央,中川愛,糸川典夫,近藤千紗,相澤良夫,坪田昭人,岩切勝彦
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] DAAsに対するNS5A領域の薬剤耐性変異を有する症例の特徴2015
- Author(s)
  大久保知美,厚川正則,島田紀朋,吉澤海,安部宏,新井康央,中川愛,糸川典夫,近藤千紗,相澤良夫,坪田昭人
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  鶴屋東館（熊本）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝炎に対するDCV/ASV療法の成績にHost因子が与える影響2015
- Author(s)
  厚川正則,島田紀朋,吉澤海,安部宏,大久保知美,新井康央,中川愛,糸川典夫,近藤千紗,松下洋子,坪田昭人,相澤良夫
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  鶴屋東館（熊本）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] 静脈瘤治療に対する抗ウイルス治療の影響2015
- Author(s)
  加藤慶三,島田紀朋,坪田昭人
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] SMV３剤併用療法の成績から見た難治要因の検討2015
- Author(s)
  島田紀朋,厚川正則,坪田昭人,吉澤海,安部宏,加藤慶三,大久保雄介,平岡淳,高口浩一,石川達,辻邦彦,豊田秀徳,熊田卓,田中靖人,相澤良夫
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日本航空（熊本）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝疾患に対するダクラタスビル･アスナプレビルの初期治療効果の検討2015
- Author(s)
  加藤慶三,塙紀子,米澤健,佐藤祥之,井家麻紀子,清水昌平,松尾亮太,坪田昭人
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪･国際館パミール（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06810
[Presentation] C型慢性肝炎Naïve症例に対するTelaprevir+Peginterferon+Ribavirin3剤療法の治療成績2014
- Author(s)
  安部宏,島田紀朋,厚川正則,加藤慶三,坪田昭人,坂本長逸,相澤良夫.
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Peg-IFN/ribavirin/telaprevir三剤併用療法における再燃に寄与する因子の検討2014
- Author(s)
  近藤千紗,厚川正則,島田紀朋,安部宏,中川愛,糸川典夫,加藤慶三,福田健,松下洋子,楢原義之,中塚雄久,岩切勝彦,川本智章,坪田昭人,相澤良夫,坂本長逸.
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎に対する3剤併用療法のHCV RNA陰性化時期がSVRに与える影響～48週延長投与例も含めた解析2014
- Author(s)
  中川愛,厚川正則,島田紀朋,安部宏,加藤慶三,近藤千紗,糸川典夫,福田健,松下洋子,中塚雄久,長田祐二,岩切勝彦,川本智章,坪田昭人,相澤良夫,坂本長逸.
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Simeprevir3剤併用療法におけるvitamin D併用療法の治療初期効果について2014
- Author(s)
  厚川正則,島田紀朋,吉澤海,安部宏,中川愛,糸川典夫,近藤千紗,坪田昭人,相澤良夫,坂本長逸.
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  神戸国際展示場・ポートピアホテル・神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] TVR3剤併用療法の早期HCV動態から見た治療効果予測2014
- Author(s)
  島田紀朋,高口浩一,井出達也,加藤慶三,坪田昭人,豊田秀徳,熊田卓,佐田通夫.
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] IL28B minor genotypeのC型慢性肝炎に対する3剤併用療法における再燃に寄与する因子の検討2014
- Author(s)
  近藤千紗,厚川正則,島田紀朋,安部宏,中川愛,糸川典夫,加藤慶三,福田健,松下洋子,楢原義之,中塚雄久,岩切勝彦,川本智章,坪田昭人,相澤良夫,坂本長逸.
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Non-responderに対するT12PR48はSVRを向上させる2014
- Author(s)
  島田紀朋, 厚川正則,坪田昭人.
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎に対するTelaprevir+Peginterferon+Ribavirin3剤療法の治療成績2014
- Author(s)
  安部宏,島田紀朋,厚川正則,坪田昭人,關伸嘉,杉田知典,会田雄太,加藤慶三,坂本長逸,相澤良夫.
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 代償性肝硬変に対するpeg-IFN/ribavirin併用療法に血清25(OH)D3濃度に与える影響2014
- Author(s)
  中川愛,厚川正則,島田紀朋,糸川典夫,近藤千紗,安良岡高志,橋本知実,福田健,松下洋子,城所秀子,楢原義之,中塚雄久,坪田昭人,岩切勝彦,川本智章,坂本長逸.
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] B型慢性肝炎に対するペグインターフェロン療法～開始直前HBe抗原からみた治療効果の検討～2014
- Author(s)
  神田達郎,島田紀朋,厚川正則,篠崎正美,三上繁,中本晋吾,新井誠人,今関文夫,坪田昭人,横須賀収.
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎IL28B minor genotypeに対するAlfacalcidol併用3剤療法についての検討；Pilot Study2014
- Author(s)
  糸川典夫,厚川正則,坪田昭人,近藤千紗,橋本知美,松下洋子,福田健,城所秀子,楢原義之,中塚雄久,金沢秀典,坂本長逸.
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Bovine lactoferrinの酸化ストレス状態における効果と作用機序～ラクトフェリンのこれから～2014
- Author(s)
  坪田昭人
- Organizer
  第4回臨床ラクトフェリンシンポジウム
- Place of Presentation
  昭和大学-旗の台キャンパス（東京都品川区）
- Year and Date
  2014-04-09
- Invited
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎における血清25（OH)D3濃度の特徴についての検討2014
- Author(s)
  新井泰央,厚川正則,島田紀朋,安部宏,大久保知美,中川愛,糸川典夫,近藤千紗,坪田昭人,相澤良夫,川本智章,坂本長逸.
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  神戸国際展示場・ポートピアホテル・神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Response-guided Peginterferonα+Ribavirin療法施行Genotype2型C型慢性肝炎の治療効果におけるIL28B遺伝子多型測定の意義2014
- Author(s)
  安部宏,石黒晴哉,島田紀朋,関伸嘉,杉田知典,会田雄太,富田陽一,永野智久,板垣宗徳,須藤訓,坪田昭人,相澤良夫.
- Organizer
  第40回日本肝臓学会東部会
- Place of Presentation
  京王プラザ（東京都新宿区）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] Telaprevir3剤療法を導入したIL28B Major genotypeのC型慢性肝炎における非SVRに関与する因子の検討2014
- Author(s)
  安部宏,島田紀朋,厚川正則,坪田昭人,關伸嘉,杉田知典,会田雄太,井家麻紀子,相澤良夫.
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  神戸国際展示場・ポートピアホテル・神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 我が国におけるC型慢性肝炎患者の血清25(OH)D3濃度の特徴2014
- Author(s)
  中川愛,厚川正則,島田紀朋,阿部宏,吉澤海,浅野徹,大久保雄介,荒木眞裕,池上正,糸川典夫,近藤千紗,中塚雄久,忠願寺義通,坪田昭人,相澤良夫,坂本長逸.
- Organizer
  第40回日本肝臓学会東部会
- Place of Presentation
  京王プラザ（東京都新宿区）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎Genotype2に対する治療効果とIL28B遺伝子多型との関連性.2013
- Author(s)
  石黒晴哉,関伸嘉,会田雄太,安部宏,井家麻紀子,加藤慶三,島田紀朋,坪田昭人,相澤良夫.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] IL28B gene and very early viral kinetics (Week-1) predict sustained virological response to triple therapy in chronic hepatitis C patients with genotype 1b and high viral load.2013
- Author(s)
  Ide T, Sata M, Takaguchi K, Toyoda H, Kumada T, Shimada N, Kato K, Tsubota A, Izumi N.
- Organizer
  The Liver Meeting, The 64th Annual Meeting of the AASLD 2013
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 早期ウイルス動態からのTelaprevir３剤併用療法の治療効果予測の検討.2013
- Author(s)
  加藤慶三,島田紀朋,豊田秀徳,井出達也,坪田昭人,高口浩一,佐田通夫,泉並木,熊田卓
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  グランドホテル高輪・新高輪（東京都港区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] TVR3剤併用療法のウイルス陰性化時期別の治療成績の検討.2013
- Author(s)
  島田紀朋,厚川正則,坪田昭人,安部宏,加藤慶三,井家麻紀子,佐藤祥之,立花浩幸,米澤健,戸田剛太郎,相澤良夫.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 血小板数低値のC型慢性肝炎に対するPSE先行3剤併用療法について.2013
- Author(s)
  近藤千紗,厚川正則,島田紀朋,坪田昭人,糸川典夫,中川愛,橋本知実,福田健,松下洋子,城所秀子,楢原義之,中塚雄久,金沢秀典,岩切勝彦,坂本長逸.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎に対する3剤併用療法の治療効果に寄与する因子～スタチン併用も含め～.2013
- Author(s)
  中川愛,厚川正則,島田紀朋,坪田昭人,近藤千紗,糸川典夫,福田健,松下洋子,楢原義之,長田祐二,中塚雄久,岩切勝彦,坂本長逸.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] IL28BゲノタイプおよびHCV G1bコア70番アミノ酸置換から見たテラプレビル,リバビリン,ペグインターフェロン３剤併用療法の治療効果の検討.2013
- Author(s)
  安部宏,島田紀朋,厚川正則,坪田昭人,関伸嘉,会田雄太,石黒晴哉,井家麻紀子,加藤慶三,相澤良夫.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] C型慢性肝炎に対するTelaprevirを含む３剤併用療法における治療成績2013
- Author(s)
  中川愛,厚川正則,島田紀朋,坪田昭人,糸川典夫,近藤千紗,福田健,松下洋子,楢原義之,中塚雄久,長田祐二,岩切勝彦,坂本長逸.
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  グランドホテル高輪・新高輪（東京都港区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 早期ウイルス動態からのTelaprevir 3剤併用療法の治療効果予測の検討.2013
- Author(s)
  加藤慶三,RGT研究会（坪田昭人）.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 脾腫を伴う血小板低値のC型慢性肝炎に対するPSE先行３剤併用療法の検討.2013
- Author(s)
  厚川正則,島田紀朋,坪田昭人,近藤千紗,糸川典夫,中川愛,福田健,楢原義之,安部宏,相澤良夫,岩切勝彦,坂本長逸.
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  グランドホテル高輪・新高輪（東京都港区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] 血清アポリポプロテインE（apoE）値はHCV持続感染の病態に関与するか？2013
- Author(s)
  相澤良夫,安部宏,關伸嘉,会田雄太,石黒晴哉,,島田紀行朋,坪田昭人.
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  グランドホテル高輪・新高輪（東京都港区）
- Data Source
  KAKENHI-PROJECT-23590995
[Presentation] B型慢性肝炎に対するPeginterferon alfa-2a単独およびSequential Therapy施行時のHBs抗原量の推移に関する検討～多施設共同研究～.2013
- Author(s)
  神田達郎,厚川正則,島田紀朋,篠崎正美,三上繁,星野容子,加藤慶三,中本晋吾,千葉哲博,新井誠人,今関文夫,坪田昭人,横須賀収.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23590995

1. MOGUSHI Kaoru (60569292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. SAITO Hirohisa (40130166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 及川恒一 (20514491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 吉田清嗣 (70345312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. WATANABE Tsunamasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
6. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. IKEGAMI Tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
8. SHINKAI Noboru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KATO Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. YOSHIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. MATSUURA Kentarou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. WAKAE kousho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. KAZUMOTO Murata

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. ITO Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. SUGIYAMA Masasya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 森川賢一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 江本直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 藤原圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 村松正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 溝上雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsubota Akihito 坪田 昭人

TSUBOTA Akihito 坪田 昭人

TSUBOTA Akihiko 坪田 昭人

Research Projects

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HBVゲノムの取り込みパターンと血中/尿中キメラDNAの肝癌再発における意義Principal Investigator

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肝癌特異的な細胞外分泌蛋白を用いた新規早期診断法確立とその実用化に向けた検証研究

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Intrahepatocellular organelle abnormalities and occult HCV that remain long-term after HCV eliminationPrincipal Investigator

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Elucidation of the stealth mechanism of infection chronicity by hepatitis B virus and drug discovery of inhibitory molecular targetsPrincipal Investigator

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Integrating multiple omics analysis for understanding the pathological mechanism of chronic hepatitis B virus infection and identifying potential molecular targets using humanized chimeric micePrincipal Investigator

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Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatmentPrincipal Investigator

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Oligonucleotide microarray-based genome-wide analysis of gene expression in oxidative stress-induced hepatitis and tumorigenesisPrincipal Investigator

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[Book] Management of Gastric Cancer: Chapter 42011

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[Journal Article] Low vitamin D levels accelerates muscle mass loss in patients with chronic liver disease2024

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[Journal Article] Association of chronic liver disease with bone diseases and muscle weakness2024

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[Journal Article] Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma.2024

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[Journal Article] Protein Kinase C Delta Is a Novel Biomarker for Hepatocellular Carcinoma.2023

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[Journal Article] Hepatocellular organellar abnormalities following elimination of hepatitis C virus2023

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[Journal Article] Insulin-like growth factor 1 predicts decompensation and long-term prognosis in patients with compensated cirrhosis2023

Author(s)

Tsubota Akihito 坪田昭人

TSUBOTA Akihito 坪田昭人

TSUBOTA Akihiko 坪田昭人