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hirao atsushi  平尾 敦

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HIRAO Atsushi  平尾 敦

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Researcher Number 90343350
Other IDs
External Links
Affiliation (Current) 2025: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help 2011 – 2024: 金沢大学, がん進展制御研究所, 教授
2005 – 2011: Kanazawa University, Division of Molecular Genetics, Cancer Research Institute, professor, がん研究所, 教授
2004: 慶應義塾大学, 医学部, 助教授
2002 – 2004: Keio University, School of Medicine, Assistant Professor, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Biological Sciences / Hematology / Tumor biology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields / Tumor biology and related fields / Tumor biology / Hematology … More
Except Principal Investigator
… More Hematology / Pediatrics / Basic Section 56010:Neurosurgery-related / Neurosurgery / Hematology Less
Keywords
Principal Investigator
造血幹細胞 / 幹細胞 / がん / 代謝 / 白血病幹細胞 / 白血病 / 幹細胞分化 / 老化 / エイジング / がん幹細胞 … More / mTOR / 脳腫瘍 / 分化 / ATM / 活性酸素 / 代謝物 / 腸内細菌叢 / オートファジー / 栄養 / leukemia / hematopoietic stem cell / SP細胞 / 幹細胞クローン / 微小環境 / 栄養シグナル / 骨髄微小環境 / 未分化性 / Ras / 寿命 / 奇形腫 / 細胞分化 / 核小体 / p38MAPK / 未分化性維持機構 / 自己複製 / ATR / アセチル化 / p53 / βカテニン / Wnt / ES細胞 / 細胞周期 / アポトーシス / 癌 … More
Except Principal Investigator
造血幹細胞 / osteoblast / アンジオポエチン / RANK / Side Population / 血管新生 / ephrin-B2 / ALCAM / 骨芽細胞 / 造血細胞移植 / 加齢 / 造血細胞移植術 / ヒト造血幹細胞 / Cell line culture / high throughput / Precision medicine / Drug screening / マルチオミクス解析 / 精密医療 / ドラッグスクリーニング / 希少悪性脳腫瘍 / 化学療法 / 脳神経疾患 / ドラッグリポジショニング / 幹細胞 / グリオーマ / 栄養源代謝 / 未分化性維持 / 栄養源シグナル / 白血病幹細胞 / 解糖系 / 細胞分化 / FOXO / 白血病 / metabolism / angiogenesis / stem cell niche / bone marrow / TIE2 / Angptl / anegiopoietin / Tie2受容体 / Hemangioblast / ES細胞 / AML1 / 血管幹細胞 / 幹細胞分化転換 / ATM / リンパ管新生 / 酸化ストレス / 代謝 / 幹細胞ニッチ / 骨髄 / TIE2受容体 / アンジオポエチン様分子 / vascular invasion / perichondrium / mesenchymal stem cell / osteoclast / ARPs / 骨髄造血 / 造血環境 / 造骨・破骨 / ALCAM接着分子 / 骨髄間葉組織 / アンジオポエチンファミリー / 血管進入 / 軟骨膜 / 間葉系幹細胞 / RANKL / 破骨細胞 / リンパ球比率 / リンパ球/骨髄球比 / CEPBPAα / IKAROS / 加齢現象 / 転写因子 / 老化 / CD34陽性細胞 / 造血幹細胞移植 / バイオマーカー / CD133陽性細胞 / 加齢マーカー / 活性酸素種 / 細胞加齢 / 一酸化窒素 / グルタチオン / 生体情報工学 / Hypoxia inducible factor / ミトコンドリア / 構造生物学 / cytochrome oxidase / メタボローム / 酸素センサー / ガスバイオロジー / 一酸化炭素 Less
  • Research Projects

    (32 results)
  • Research Products

    (305 results)
  • Co-Researchers

    (46 People)
  •  リソソームをハブとした代謝ステムネス制御機構の解明とがん治療法への応用Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kanazawa University
  •  Elucidation of molecular mechanisms of hematopoietic stem agingPrincipal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Kanazawa University
  •  Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines

    • Principal Investigator
      平石 哲也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Niigata University
  •  Development of new preventive or therapeutic strategies for hematopoietic neoplasms based on metabolic analysis.Principal Investigator

    • Principal Investigator
      Hirao Atsushi
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Kanazawa University
  •  Identification of critical metabolic pathways and metabolites that regulate therapeutic resistance and stemnessPrincipal Investigator

    • Principal Investigator
      Hirao Atsushi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kanazawa University
  •  Crosstalk between genomic abnormality and transcription activity for acquisition of stem cell property of cancerPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Kanazawa University
  •  過栄養ストレスによる幹細胞運命決定機構とエイジングPrincipal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  幹細胞発生・分化におけるオートファジーチェックポイント機構Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  幹細胞エイジングを制する栄養環境シグナルメディエーターPrincipal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  A study of microenvironment for maintenance or acquisition of malignant propertyPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Kanazawa University
  •  Role of metabolic regulation in leukemia stem cells

    • Principal Investigator
      Ohta Kumiko
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  Drag repositioning for malignant glioma targeting glioma stem cells

    • Principal Investigator
      Nakada Mitsutoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University
  •  ストレス応答を介したがん幹細胞ニッチシグナルの解明Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Mechanisms of expansion of hematopoietic stem cell clonesPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  Role of nutrient signals in stem cell regulation in tumorsPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Kanazawa University
  •  がん幹細胞性獲得・維持機構とニッチシグナルのクロストークPrincipal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Understanding of molecular mechanisms regulating leukemia stem cell behavior by multi-omics analysisPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kanazawa University
  •  腫瘍悪性度進展における未分化性獲得メカニズムの解明Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kanazawa University
  •  Roles of longevity/senescence-relating molecules in the development, maintenance and differentiation of leukemia stem cellsPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  Research on aging of human hematopoietic stem cells

    • Principal Investigator
      KAWANO Yoshifumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kagoshima University
  •  普遍的幹細胞制御機構と腫瘍細胞分化Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Aging of human hematopoietic stem cells - Establishment of aging evaluation method of hematopoietic stem cell-

    • Principal Investigator
      KAWANO Yoshifumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kagoshima University
  •  Molecular mechanisms for regulation of hematopoietic and leukemia stem cell population by nucleolar moleculesPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
  •  幹細胞自己複製と寿命・老化制御における分子基盤の共通性Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Biomedical Application of Gas Biology through Multidisciplinary Approaches

    • Principal Investigator
      SUEMATSU Makoto
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Keio University
  •  Molecular mechanisms for regulation of hematopoietic stem cells and leukemic stem cellsPrincipal Investigator

    • Principal Investigator
      HIRAO Atsushi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kanazawa University
      Keio University
  •  アポトーシス誘導特異的p53活性化制御と生理的意義Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  “自己複製"と“寿命・老化"制御における分子基盤の共通性Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  ChK2によるp53の選択的活性化制御Principal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Wntシグナル制御による胚幹(ES)細胞からの造血幹細胞誘導の試みPrincipal Investigator

    • Principal Investigator
      平尾 敦
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Transdifferentiation of hematopoietic stem cells and endothelial progenitors

    • Principal Investigator
      OIKE Yuichi, 須田 年生
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Differentiation of Mesenchymal Stem Cells in Bone Marrow

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Keio University
      Kumamoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent Other

  • [Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017

    • Author(s)
      Naka K., Hirao A
    • Total Pages
      5
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017

    • Author(s)
      Naka K., Hirao A
    • Total Pages
      5
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017

    • Author(s)
      Naka K., Hirao A
    • Total Pages
      5
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Book] Molecular Pathogenesis and Treatment of Chronic Myelogenous leukemia2015

    • Author(s)
      Hirao A, Tadokoro Y, Ueno M
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Book] Molecular Pathogenesis and Treatment of Chronic Myelogenous leukemia2015

    • Author(s)
      Hirao A, Tadokoro Y, Ueno M
    • Publisher
      Springer
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Journal Article] Induction of open-form bile canaliculus formation by hepatocytes for evaluation of biliary drug excretion2023

    • Author(s)
      Arakawa H, Nakazono Y, Matsuoka N, Hayashi M, Shirasaka Y, Hirao A, Tamai I.
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1

    • DOI

      10.1038/s42003-023-05216-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-22KJ1477, KAKENHI-PROJECT-23K27437
  • [Journal Article] Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.2023

    • Author(s)
      Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma S, Sato T, Nakagawa T and Tanuma N.
    • Journal Title

      Nature Communications.

      Volume: 14(1) Issue: 1 Pages: 8095-8095

    • DOI

      10.1038/s41467-023-43630-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09482, KAKENHI-PROJECT-21K11593, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-23K24762, KAKENHI-PROJECT-23K27437
  • [Journal Article] Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation2023

    • Author(s)
      Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A.
    • Journal Title

      Cell Death Disease

      Volume: 14 Issue: 9 Pages: 642-642

    • DOI

      10.1038/s41419-023-06168-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K14729, KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K08448, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-23K06672, KAKENHI-PROJECT-23K07855, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-23K27437, KAKENHI-PROJECT-23K27624
  • [Journal Article] Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line2023

    • Author(s)
      Noguchi Masafumi、Kohno Susumu、Pellattiero Anna、Machida Yukino、Shibata Keitaro、Shintani Norihito、Kohno Takashi、Gotoh Noriko、Takahashi Chiaki、Hirao Atsushi、Scorrano Luca、Kasahara Atsuko
    • Journal Title

      Cell Death & Disease

      Volume: 14 Issue: 4 Pages: 1-10

    • DOI

      10.1038/s41419-023-05768-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15017, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-22K20654, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-21H02671, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-23K27437
  • [Journal Article] MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells2023

    • Author(s)
      Fukasawa Kazuya、Lyu Jiajun、Kubo Takuya、Tanaka Yuki、Suzuki Akane、Horie Tetsuhiro、Tomizawa Akane、Osumi Ryoma、Iwahashi Sayuki、Tokumura Kazuya、Murata Misato、Kobayashi Masaki、Todo Tomoki、Hirao Atsushi、Hinoi Eiichi
    • Journal Title

      Cancer Research Communications

      Volume: 3 Issue: 1 Pages: 148-159

    • DOI

      10.1158/2767-9764.crc-22-0243

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-22H00483, KAKENHI-PROJECT-20H03407, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K20843
  • [Journal Article] Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects2023

    • Author(s)
      Tamai S, Ichinose T, Jiapaer S, Hirai N, Sabit H, Tanaka S, Kinoshita M, Kobayashi M, Hirao A, Nakada M.
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 7 Pages: 2920-2930

    • DOI

      10.1111/cas.15827

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-22H00484, KAKENHI-PROJECT-23K27437
  • [Journal Article] SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability2022

    • Author(s)
      Hiraiwa Manami、Fukasawa Kazuya、Iezaki Takashi、Sabit Hemragul、Horie Tetsuhiro、Tokumura Kazuya、Iwahashi Sayuki、Murata Misato、Kobayashi Masaki、Suzuki Akane、Park Gyujin、Kaneda Katsuyuki、Todo Tomoki、Hirao Atsushi、Nakada Mitsutoshi、Hinoi Eiichi
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 22-22

    • DOI

      10.1038/s42003-021-02950-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-20H03407, KAKENHI-PROJECT-20J21092, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K15350, KAKENHI-PROJECT-21K20843
  • [Journal Article] The Role of Nutrients in Maintaining Hematopoietic Stem Cells and Healthy Hematopoiesis for Life2022

    • Author(s)
      Yuko Tadokoro and Atsushi Hirao
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 3 Pages: 1574-1589

    • DOI

      10.3390/ijms23031574

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-21K19502
  • [Journal Article] Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes2022

    • Author(s)
      Harada Y, Sujino T, Miyamoto K, Nomura E, Yoshimatsu Y, Tanemoto S, Umeda S, Ono K, Mikami Y, Nakamoto N, Takabayashi K, Hosoe N, Ogata H, Ikenoue T, Hirao A, Kubota Y, Kanai T.
    • Journal Title

      iScience

      Volume: 25 Issue: 4 Pages: 104021-104021

    • DOI

      10.1016/j.isci.2022.104021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19H03397, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-21K07084, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-22K07994, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K19502
  • [Journal Article] Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma2022

    • Author(s)
      Jing Yongwei、Kobayashi Masahiko、Vu Ha Thi、Kasahara Atsuko、Chen Xi、Pham Loc Thi、Kurayoshi Kenta、Tadokoro Yuko、Ueno Masaya、Todo Tomoki、Nakada Mitsutoshi、Hirao Atsushi
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 8 Pages: 2716-2726

    • DOI

      10.1111/cas.15451

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-22H00483, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264
  • [Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022

    • Author(s)
      Pham Loc Thi、Peng Hui、Ueno Masaya、Kohno Susumu、Kasada Atuso、Hosomichi Kazuyoshi、Sato Takehiro、Kurayoshi Kenta、Kobayashi Masahiko、Tadokoro Yuko、Kasahara Atsuko、Shoulkamy Mahmoud I.、Xiao Bo、Worley Paul F.、Takahashi Chiaki、Tajima Atsushi、Hirao Atsushi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 621 Pages: 74-79

    • DOI

      10.1016/j.bbrc.2022.06.089

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01356, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264, KAKENHI-PUBLICLY-21H00342
  • [Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021

    • Author(s)
      Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1666-1679

    • DOI

      10.1038/s41598-021-81076-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07558
  • [Journal Article] The GPI-anchored protein CD109 protects hematopoietic progenitor cells from undergoing erythroid differentiation induced by TGF-β2021

    • Author(s)
      Tanabe Mikoto、Hosokawa Kohei、Nguyen Mai Anh Thi、Nakagawa Noriharu、Maruyama Kana、Tsuji Noriaki、Urushihara Ryota、Espinoza Luis、Elbadry Mahmoud I.、Mohiuddin Md、Katagiri Takamasa、Ono Masanori、Fujiwara Hiroshi、Chonabayashi Kazuhisa、Yoshida Yoshinori、Yamazaki Hirohito、Hirao Atsushi、Nakao Shinji
    • Journal Title

      Leukemia

      Volume: 36 Issue: 3 Pages: 847-855

    • DOI

      10.1038/s41375-021-01463-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03686, KAKENHI-PROJECT-20K08707, KAKENHI-PROJECT-21K08367, KAKENHI-PROJECT-21K19502
  • [Journal Article] CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway2021

    • Author(s)
      Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
    • Journal Title

      Oncogene

      Volume: ー Issue: 15 Pages: 2803-2815

    • DOI

      10.1038/s41388-021-01745-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03407, KAKENHI-PROJECT-18J22107, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K15350
  • [Journal Article] Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway2021

    • Author(s)
      Baba Tomohisa、Yoshida Takeshi、Tanabe Yamato、Nishimura Tatsunori、Morishita Soji、Gotoh Noriko、Hirao Atsushi、Hanayama Rikinari、Mukaida Naofumi
    • Journal Title

      Cell Death & Disease

      Volume: 12 Issue: 4 Pages: 322-322

    • DOI

      10.1038/s41419-021-03587-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19K22557, KAKENHI-PUBLICLY-20H05029, KAKENHI-PROJECT-21H02761
  • [Journal Article] Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples2020

    • Author(s)
      Ueno Masaya、Tomita Takuya、Arakawa Hiroshi、Kakuta Takahiro、Yamagishi Tada-aki、Terakawa Jumpei、Daikoku Takiko、Horike Shin-ichi、Si Sha、Kurayoshi Kenta、Ito Chiaki、Kasahara Atsuko、Tadokoro Yuko、Kobayashi Masahiko、Fukuwatari Tsutomu、Tamai Ikumi、Hirao Atsushi、Ogoshi Tomoki
    • Journal Title

      Communications Chemistry

      Volume: 3 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s42004-020-00430-w

    • NAID

      120006939157

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-19H00909, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19K18691
  • [Journal Article] Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma2020

    • Author(s)
      Jiapaer Shabierjiang、Furuta Takuya、Dong Yu、Kitabayashi Tomohiro、Sabit Hemragul、Zhang Jiakang、Zhang Guangtao、Tanaka Shingo、Kobayashi Masahiko、Hirao Atsushi、Nakada Mitsutoshi
    • Journal Title

      Current Pharmaceutical Design

      Volume: 26 Issue: 36 Pages: 4675-4684

    • DOI

      10.2174/1381612826666200429092742

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02910
  • [Journal Article] Expansion of senescent megakaryocyte-lineage cells maintains CML cell leukemogenesis2020

    • Author(s)
      Tanabe Yamato、Kawamoto Shimpei、Takaku Tomoiku、Morishita Soji、Hirao Atsushi、Komatsu Norio、Hara Eiji、Mukaida Naofumi、Baba Tomohisa
    • Journal Title

      Blood Advances

      Volume: 4 Issue: 24 Pages: 6175-6188

    • DOI

      10.1182/bloodadvances.2020003117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07446, KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19H01033
  • [Journal Article] Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1.2019

    • Author(s)
      Hasegawa T, Kikuta J, Sudo T, Matsuura Y, Matsui T, Simmons S, Ebina K, Hirao M, Okuzaki D, Yoshida Y, Hirao A, Kalinichenko VV, Yamaoka K, Takeuchi T, Ishii M.
    • Journal Title

      Nat Immunol.

      Volume: 20 Issue: 12 Pages: 1631-1643

    • DOI

      10.1038/s41590-019-0526-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17906, KAKENHI-PROJECT-19K23967, KAKENHI-PROJECT-19H05657, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01044, KAKENHI-PROJECT-18K15080, KAKENHI-PROJECT-18K16114, KAKENHI-PROJECT-16H06276
  • [Journal Article] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function2019

    • Author(s)
      Imanishi Takayuki、Unno Midori、Kobayashi Wakana、Yoneda Natsumi、Matsuda Satoshi、Ikeda Kazutaka、Hoshii Takayuki、Hirao Atsushi、Miyake Kensuke、Barber Glen N、Arita Makoto、Ishii Ken J、Akira Shizuo、Saito Takashi
    • Journal Title

      Life Science Alliance

      Volume: 2 Issue: 1 Pages: e201800282-e201800282

    • DOI

      10.26508/lsa.201800282

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19576, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-18H02672, KAKENHI-PROJECT-16K08852, KAKENHI-PROJECT-17K19585, KAKENHI-PROJECT-17K19937, KAKENHI-PROJECT-16H06276
  • [Journal Article] Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma2019

    • Author(s)
      Kitabayashi Tomohiro、Dong Yu、Furuta Takuya、Sabit Hemragul、Jiapaer Shabierjiang、Zhang Jiakang、Zhang Guangtao、Hayashi Yasuhiko、Kobayashi Masahiko、Domoto Takahiro、Minamoto Toshinari、Hirao Atsushi、Nakada Mitsutoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 10049-10049

    • DOI

      10.1038/s41598-019-46454-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-18H02910, KAKENHI-PROJECT-18K19577
  • [Journal Article] Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress2018

    • Author(s)
      Tadokoro Yuko、Hoshii Takayuki、Yamazaki Satoshi、Eto Koji、Ema Hideo、Kobayashi Masahiko、Ueno Masaya、Ohta Kumiko、Arai Yuriko、Hara Eiji、Harada Kenichi、Oshima Masanobu、Oshima Hiroko、Arai Fumio、Yoshimura Akihiko、Nakauchi Hiromitsu、Hirao Atsushi
    • Journal Title

      Cell Stem Cell

      Volume: 22 Issue: 5 Pages: 713-725

    • DOI

      10.1016/j.stem.2018.04.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09919, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-18H05095, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K19585, KAKENHI-INTERNATIONAL-15K21751, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04164
  • [Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress. Cell Stem Cell2018

    • Author(s)
      Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
    • Journal Title

      Cell Stem Cell

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress.2018

    • Author(s)
      Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
    • Journal Title

      Cell Stem Cell

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Journal Article] Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells2018

    • Author(s)
      Hui Peng, Atsuo Kasada, Masaya Ueno, Takayuki Hoshii, Yuko Tadokoro, Naho Nomura, Chiaki Ito, Yusuke Takase, Ha Thi Vu, Masahiko Kobayashi, Bo Xiao, Paul F. Worley, Atsushi Hirao
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 495 Issue: 1 Pages: 1129-1135

    • DOI

      10.1016/j.bbrc.2017.11.140

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K09919, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361
  • [Journal Article] Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.2018

    • Author(s)
      Vu HT, Kobayashi M, Hegazy AM, Tadokoro Y, Ueno M, Kasahara A, Takase Y, Nomura N, Peng H, Ito C, Ino Y, Todo T, Nakada M, Hirao A
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 8 Pages: 2497-2508

    • DOI

      10.1111/cas.13695

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K09919, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K19585, KAKENHI-PROJECT-17K17758, KAKENHI-PROJECT-16H06276
  • [Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress.2018

    • Author(s)
      Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
    • Journal Title

      Cell Stem Cell

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Journal Article] JLP-JNK signaling protects cancer cells from reactive oxygen species-induced cell death2018

    • Author(s)
      Li Rong、Gunarta I. Ketut、Suzuki Ryusuke、Boldbaatar Jambaldorj、Nakazato Ryota、Yuliana Dewi、Davaakhuu Gantulga、Oyunsuren Tsendsuren、Takamatsu Nobuhiko、Kobayashi Masahiko、Hirao Atsushi、Yoshioka Katsuji
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 501 Issue: 3 Pages: 724-730

    • DOI

      10.1016/j.bbrc.2018.05.055

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K08579, KAKENHI-PROJECT-17K19585
  • [Journal Article] Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression2017

    • Author(s)
      Ali Mohamed A. E.、Fuse Kyoko、Tadokoro Yuko、Hoshii Takayuki、Ueno Masaya、Kobayashi Masahiko、Nomura Naho、Vu Ha Thi、Peng Hui、Hegazy Ahmed M.、Masuko Masayoshi、Sone Hirohito、Arai Fumio、Tajima Atsushi、Hirao Atsushi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11442-11442

    • DOI

      10.1038/s41598-017-11909-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09919, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-17H04208
  • [Journal Article] Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug2017

    • Author(s)
      Dong Y, Furuta T, Sabit H, Kitabayashi T, Jiapaer S, Kobayashi M, Ino Y, Todo T, Teng L, Hirao A, Zhao SG, Nakada M
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 67 Pages: 111728-111741

    • DOI

      10.18632/oncotarget.22904

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K15645
  • [Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice2016

    • Author(s)
      Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.
    • Journal Title

      Blood

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Journal Article] Cooperative networks for stem cell homeostasis in normal and malignant hematopoiesis: from metabolism to epigenetics.2016

    • Author(s)
      Hirao A.
    • Journal Title

      Int J Hematol

      Volume: 103 Issue: 6 Pages: 605-6

    • DOI

      10.1007/s12185-016-2012-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-15H02361
  • [Journal Article] Novel oral transforming growth factor-β signaling inhibitor EW-7197 eradicates CML-initiating cells.2016

    • Author(s)
      Naka K, Ishihara K, Jomen Y, Jin CH, Kim DH, Gu YK, Jeong ES, Li S, Krause DS, Kim DW, Bae E, Takihara Y, Hirao A, Oshima H, Oshima M, Ooshima A, Sheen YY, Kim SJ, Kim DK.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 2 Pages: 140-148

    • DOI

      10.1111/cas.12849

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038, KAKENHI-PROJECT-16K07111
  • [Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice2016

    • Author(s)
      Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.
    • Journal Title

      Blood

      Volume: 127 Pages: 2607-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Journal Article] The PI3K-Akt pathway controls IL-10-producing regulatory B cells.2016

    • Author(s)
      MatsushitaT, Huu DL, Hamaguchi Y, Hasegawa M, Naka K, Hirao A, Muramatsu M, Takehara K, Fujimoto M.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 印刷中 Issue: 4 Pages: 21496-21509

    • DOI

      10.1016/j.jaci.2015.12.1319

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-26290038
  • [Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.2016

    • Author(s)
      Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N
    • Journal Title

      Blood

      Volume: 印刷中 Issue: 21 Pages: 2607-17

    • DOI

      10.1182/blood-2015-10-673087

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20969, KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16K08733
  • [Journal Article] Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism.2015

    • Author(s)
      .Fahkri H, Zhang B, Fajol A, Hernando N, Elvira B, Mannheim JG, Pichler BJ, Daniel C, Amann K, Hirao A, Haight J, Mak TW, Lang F, Föller M.
    • Journal Title

      Pflugers Arch.

      Volume: 467 Issue: 9 Pages: 1871-1880

    • DOI

      10.1007/s00424-014-1625-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Journal Article] Foxo3a Inhibitors of Microbial Origin, JBIR-141 and JBIR-1422015

    • Author(s)
      Teppei Kawahara, Noritaka Kagaya, Yuichi Masuda, Takayuki Doi, Miho Izumikawa, Kumiko Ohta, Atsushi Hirao, Kazuo Shin-ya
    • Journal Title

      Organic letters

      Volume: 17 Issue: 21 Pages: 5476-5479

    • DOI

      10.1021/acs.orglett.5b02842

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19548, KAKENHI-PROJECT-26850068, KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H02361
  • [Journal Article] S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation2015

    • Author(s)
      Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K
    • Journal Title

      Molecular and cellular biology

      Volume: 20 Issue: 20 Pages: 3517-3527

    • DOI

      10.1128/mcb.00343-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18365, KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
  • [Journal Article] Crosstalk between the RB-pathway and AKT signalling forms a Quiescence-Senescence switch.2014

    • Author(s)
      Imai, Y., Takahashi, A., Hanyuu, A., Hori, S., Sato, S., Naka, K., Hirao, A., Ohtani, N., Hara, E.
    • Journal Title

      Cell Reports

      Volume: 7 Issue: 1 Pages: 194-207

    • DOI

      10.1016/j.celrep.2014.03.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24650625, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25290046, KAKENHI-PROJECT-26250028
  • [Journal Article] Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients.2014

    • Author(s)
      Ali MA, Naka K, Yoshida A, Fuse K, Kasada A, Hoshii T, Tadokoro Y, Ueno M, Ohta K, Kobayashi M, Takahashi C, Hirao A.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 450 Issue: 1 Pages: 837-843

    • DOI

      10.1016/j.bbrc.2014.06.066

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26460361, KAKENHI-PROJECT-26640070
  • [Journal Article] Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals.2014

    • Author(s)
      Yamada D, Hoshii T, Tanaka S, Hegazy AM, Kobayashi M, Tadokoro Y, Ohta K, Ueno M, Ali MAE, Hirao A.
    • Journal Title

      J Biochem.

      Volume: 155 Issue: 4 Pages: 227-33

    • DOI

      10.1093/jb/mvt112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26460361
  • [Journal Article] Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis.2014

    • Author(s)
      Hoshii T, Matsuda S, Hirao A.
    • Journal Title

      J Biochem.

      Volume: 156 Issue: 2 Pages: 73-83

    • DOI

      10.1093/jb/mvu037

    • NAID

      40020155036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25670236, KAKENHI-PROJECT-25670447
  • [Journal Article] Abundant nucleostemin expression supports the undifferentiated properties of germ cell tumors2013

    • Author(s)
      Uema, N., Ooshio, T., Harada, K., Naito, M., Naka, K., Hoshii, T., Tadokoro, Y., Ohta, K., Ali, M.A., Katano, M., Soga, T., Nakanuma, Y., Okuda, A., Hirao, A.
    • Journal Title

      Am. J. Pathol.

      Volume: 183 Issue: 2 Pages: 592-603

    • DOI

      10.1016/j.ajpath.2013.04.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25293082, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25670147
  • [Journal Article] Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.2013

    • Author(s)
      Hoshii T, Kasada A, Hatakeyama T, Ohtani M, Tadokoro Y, Naka K, Ikenoue T, Ikawa T, Kawamoto H, Fehling HJ, Araki K, Yamamura K, Matsuda S, Hirao A
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 111 Issue: 10 Pages: 3805-3810

    • DOI

      10.1073/pnas.1320265111

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118004, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24249057, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460602, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25670236, KAKENHI-PROJECT-25670447, KAKENHI-PROJECT-221S0001
  • [Journal Article] Mechanistic/mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A, Hoshii T.
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 8 Pages: 977-82

    • DOI

      10.1111/cas.12189

    • NAID

      120005830607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967
  • [Journal Article] MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.2013

    • Author(s)
      Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.
    • Journal Title

      J Exp Med.

      Volume: 210 Issue: 12 Pages: 2661-2673

    • DOI

      10.1084/jem.20130112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460492
  • [Journal Article] PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi-1 expression and nuclear translocation of RORγ2012

    • Author(s)
      Kurebayashi Y. Nagai S. Ikejiri A. Ohtani M. Ichiyama K. Baba Y. Yamada T. Egami S. Hoshii T. Hirao A. Matsuda S. Koyasu S.
    • Journal Title

      Cell Reports

      Volume: 1 Issue: 4 Pages: 360-373

    • DOI

      10.1016/j.celrep.2012.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-22590439, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23790546, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-23118511
  • [Journal Article] mTORC1 is essential for leukemia-propagation but not stem cell self-renewal2012

    • Author(s)
      Hoshii T. TadokoroY. Naka K. Ooshio T. Muraguchi T. Sugiyama N. Soga T. Araki K. Yamamura K. Hirao A.
    • Journal Title

      J. Clin. Invest.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Nucleostemin in injury-induced liver regeneration2012

    • Author(s)
      ShugoH, Ooshio T. Naito M, Naka K, Hoshii T. Tadokoro Y. Muraguchi T. Tamas A. Uema N. Yamashita T. Nakamoto Y. Suda T. Kaneko S. Hirao A.
    • Journal Title

      Stem Cells and Develop.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Journal Article] Nucleostemin in injury-induced liver regeneration2012

    • Author(s)
      ShugoH, Ooshio T. Naito M, Naka K, Hoshii T. Tadokoro Y. Muraguchi T. Tamas A. Uema N. Yamashita T. Nakamoto Y. Suda T. Kaneko S. Hirao A.
    • Journal Title

      Stem Cells and Develop.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] mTORC1 is essential for leukemia-propagation but not stemcell self-renewal2012

    • Author(s)
      Hoshii T. TadokoroY. Naka K. Ooshio T. Muraguchi T. Sugiyama N. Soga T. Araki K. Yamamura K. Hirao
    • Journal Title

      J Clin. Invest.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Journal Article] mTORC1 in Intestinal CD11c+CD11b+Dendritic Cells Regulates Intestinal Homeostasis by Promoting IL-10 Production2012

    • Author(s)
      Ohtani M, Hoshii T, Fujii H, Koyasu S, Hirao A, Matsuda S.
    • Journal Title

      J Immunol

      Volume: 188 Issue: 10 Pages: 4736-40

    • DOI

      10.4049/jimmunol.1200069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-22590437, KAKENHI-PROJECT-22590439, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23118511, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23790546, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967
  • [Journal Article] 14-3-3 sigma regulates B-cell homeostasis through stabilization of FOXO12011

    • Author(s)
      Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 108 Issue: 4 Pages: 1555-60

    • DOI

      10.1073/pnas.1017729108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Invasion precedestumor mass formation in a malignant braintumor model of genetically modified neural stem cells2011

    • Author(s)
      Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka S, Akahata M, Kai K, Sugimoto H, Hirao A, Saya H
    • Journal Title

      Neoplasia

      Volume: 13(9) Issue: 9 Pages: 784-91

    • DOI

      10.1593/neo.11624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J00382, KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
  • [Journal Article] Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells2011

    • Author(s)
      Motohara T, Masuko S, Ishimoto T, Yae T, Onishi N, Muraguchi T, Hirao A, Matsuzaki Y, Tashiro H, Katabuchi H, Saya H, Nagano O.
    • Journal Title

      Carcinogenesis

      Volume: 32 Issue: 11 Pages: 1597-606

    • DOI

      10.1093/carcin/bgr183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
  • [Journal Article] Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer2011

    • Author(s)
      El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R.
    • Journal Title

      PLoS Genet

      Volume: 7 Issue: 5 Pages: e1001385-e1001385

    • DOI

      10.1371/journal.pgen.1001385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
  • [Journal Article] Maintenance of genomic integrity in hematopoietic stem cells2011

    • Author(s)
      Naka K, Hirao A.
    • Journal Title

      Int J Hematol

      Volume: 93 Issue: 4 Pages: 434-9

    • DOI

      10.1007/s12185-011-0793-z

    • NAID

      10029534293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
  • [Journal Article] Molecular pathology of tumor-initiating cells : lessons from Philadelphia chromosome-positive leukemia2011

    • Author(s)
      Naka K, Hoshii T, Tadokoro Y, Hirao A.
    • Journal Title

      Pathol Int

      Volume: 61 Issue: 9 Pages: 501-8

    • DOI

      10.1111/j.1440-1827.2011.02688.x

    • NAID

      10031185122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23118511, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23791076
  • [Journal Article] Intrinsic Cooperation between p16INK4a and p21Waf1/Cip1 in the Onset of Cellular Senescence and Tumor Suppression In vivo2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S, Hara E, Ohtani N.
    • Journal Title

      Cancer Res

      Volume: 70 Issue: 22 Pages: 7381-90

    • DOI

      10.1158/0008-5472.can-10-0801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.2010

    • Author(s)
      Naka K, Hoshii T, Muraguchi T, Tadokoro Y, Ooshio T, Kondo Y, Nakao S, Motoyama N, Hirao A
    • Journal Title

      Nature 463

      Pages: 676-680

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] TGFβ-FOXO signalling maintains leukaemia-initiating cells in chronic myeoid leukaemia2010

    • Author(s)
      Naka K, Hoshii T, Muraguchi T, Tadokoro Y, Ooshio T, Kondo Y, Nakao S, Motoyama N, Hirao A
    • Journal Title

      Nature

      Volume: 463 Issue: 7281 Pages: 676-80

    • DOI

      10.1038/nature08734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells2010

    • Author(s)
      Naka K, Hoshii T, Hirao A.
    • Journal Title

      Cancer Sci

      Volume: 101 Issue: 7 Pages: 1577-81

    • DOI

      10.1111/j.1349-7006.2010.01584.x

    • NAID

      10026594276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22790906
  • [Journal Article] Regulation of the HIF-1α level is essential for hematopoietic stem cells.2010

    • Author(s)
      Takubo K, Goda N, Yamada W, Ikeda E Kubota Y, Shima H Johnson RS, Hirao A, Suematsu M, Suda T
    • Journal Title

      Cell Stem Cell (in press)

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells2010

    • Author(s)
      Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T.
    • Journal Title

      Cell Stem Cell

      Volume: 7 Issue: 3 Pages: 391-402

    • DOI

      10.1016/j.stem.2010.06.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Real-time in vivo imaging of p16Ink4a reveals cross talk with p532009

    • Author(s)
      Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann DJ, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E.
    • Journal Title

      J Cell Biol

      Volume: 186 Issue: 3 Pages: 393-407

    • DOI

      10.1083/jcb.200904105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.2009

    • Author(s)
      Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada JI, Hirao A
    • Journal Title

      Proc Natl Acad Sci U S A. 106

      Pages: 17163-17168

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin2009

    • Author(s)
      Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada JI, Hirao A.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 106 Issue: 40 Pages: 17163-8

    • DOI

      10.1073/pnas.0905016106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Journal Article] Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity2008

    • Author(s)
      Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, Hirao A.
    • Journal Title

      Stem Cells 26

      Pages: 3237-3246

    • Data Source
      KAKENHI-PROJECT-19591257
  • [Journal Article] Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity2008

    • Author(s)
      Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, Hirao A.
    • Journal Title

      Stem Cells 12

      Pages: 3237-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest2008

    • Author(s)
      Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada W, Arai F, Hirao A, Suda T.
    • Journal Title

      Cell Stem Cell 2

      Pages: 170-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells2008

    • Author(s)
      Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M.
    • Journal Title

      EMBO J. 27

      Pages: 1671-81

    • NAID

      120001670272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells2008

    • Author(s)
      Naka K, Muraguchi T, Hoshii T, Hirao A.
    • Journal Title

      Antioxid Redox Signal 10

      Pages: 1883-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Identification of Stem Cells During Prepubertal Spermatogenesis Via Monitoring of Nucleostemin Promoter Activity.2008

    • Author(s)
      Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, *Hirao A
    • Journal Title

      Stem Cells 26

      Pages: 3237-3246

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007

    • Author(s)
      Miyamoto K, Araki YK, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.
    • Journal Title

      Cell Stem Cell 1

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Foxo3a Is Essential for Maintenance of the Hematopoietic Stem Cell Pool.2007

    • Author(s)
      Miyamoto K.et al.Hirao A(計18名中18番)
    • Journal Title

      Cell Stem Cell 1(印刷中)

    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death2007

    • Author(s)
      Iwanaga A, Sato T, Sugihara K, Hirao A, Takakura N, Okamoto H, Asano M, Yoshioka K.
    • Journal Title

      Neurosci Lett 429

      Pages: 43-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Foxo3a Is Essential for Maintenance of the Hematopoietic Stem Cell Pool.2007

    • Author(s)
      Miyamoto K.et al., Hirao A(計18名中18番)
    • Journal Title

      Cell Stem Cell 1(発行予定)

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007

    • Author(s)
      Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A
    • Journal Title

      J Immunol 178

      Pages: 103-110

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes2007

    • Author(s)
      Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A.
    • Journal Title

      J Immunol 178

      Pages: 103-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.2007

    • Author(s)
      Zaugg K.et al., Hirao A(計9名中7番)
    • Journal Title

      Proc Natl Acad Sci U S A. 104

      Pages: 3805-3810

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007

    • Author(s)
      Ito K, et al., Hirao A(計14名中14番)
    • Journal Title

      J lmmunol. 178

      Pages: 103-110

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes2007

    • Author(s)
      Zaugg K, Su YW, Reilly PT, Moolani Y, Cheung CC, Hakem R, Hirao A, Liu Q, Elledge SJ, Mak TW.
    • Journal Title

      Proc Natl Acad Sci U S A 104

      Pages: 3805-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Regulation of the self-renewal ability of tissue stem cells by tumor-related genes2007

    • Author(s)
      Naka K, Ohmura M, Hirao A.
    • Journal Title

      Cancer Biomark 3

      Pages: 193-201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals2007

    • Author(s)
      Ohtani N, Imamura Y, Yamakoshi K, Hirota F, Nakayama R, Kubo Y, Ishimaru N, Takahashi A, Hirao A, Shimizu T, Mann DJ, Saya H, Hayashi Y, Arase S, Matsumoto M, Kazuki N, Hara E.
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 15034-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.2007

    • Author(s)
      Zaugg K., et al.Hirao A(計9名中7番)
    • Journal Title

      Proc Natl Acad Sci U S A. 104

      Pages: 3805-10

    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007

    • Author(s)
      Ito K., et al.Hirao A(計14名中14番)
    • Journal Title

      J Immunol. 178

      Pages: 103-10

    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006

    • Author(s)
      Ito K., et al.Hirao A(計11名中2番)
    • Journal Title

      Nature Med. 12

      Pages: 446-451

    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.2006

    • Author(s)
      Ito K.et al., Hirao A(計7名中2番)
    • Journal Title

      Biochem Biophys Res Commun. 351

      Pages: 993-998

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006

    • Author(s)
      Ito K.et al., Hirao A(計11名中2番)
    • Journal Title

      Nature Med. 12

      Pages: 446-451

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006

    • Author(s)
      Ito K, Hirao A(他9名)
    • Journal Title

      Nature Medicine (印刷中)

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury.2006

    • Author(s)
      Miyao N, Suzuki Y, Takeshita K, Kudo H, Ishii M, Hiraoka R, Nishio K, Tamatani T, Sakamoto S, Suematsu M, Tsumura H, Ishizaka A, Yamaguchi K
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 290

    • Data Source
      KAKENHI-PROJECT-17GS0419
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006

    • Author(s)
      Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T.
    • Journal Title

      Nature Med. 12

      Pages: 446-451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis2006

    • Author(s)
      Takubo K, Hirao A, Ohmura M, Azuma M, Arai F, Nagamatsu G, Suda T.
    • Journal Title

      Biochem Biophys Res Commun 351

      Pages: 993-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.2006

    • Author(s)
      Ito K., et al.Hirao A(計7名中2番)
    • Journal Title

      Biochem Biophys Res Commun. 351

      Pages: 993-8

    • Data Source
      KAKENHI-PROJECT-18390281
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006

    • Author(s)
      Ito K, Hirao A. et al.
    • Journal Title

      Nature Medicine 12(4)

      Pages: 446-451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006

    • Author(s)
      Ito K, Hirao A(他9名)
    • Journal Title

      Nature Medicine (印刷中)

    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005

    • Author(s)
      Azuma M, Hirao A. et al.
    • Journal Title

      Biochem Biophys Res Commun. 338(2)

      Pages: 1164-1170

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005

    • Author(s)
      Azuma M, Hirao A(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 338・2

      Pages: 1164-1170

    • Data Source
      KAKENHI-PROJECT-17045029
  • [Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005

    • Author(s)
      Azuma M, Hirao A(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 338・2

      Pages: 1164-1170

    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] Collaboration of Brcal and Chk2 in tumorigenesis.2004

    • Author(s)
      McPherson JP, Lemmers B, Hirao A, et al.
    • Journal Title

      Genes Dev 18(10)

      Pages: 1144-1153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche.2004

    • Author(s)
      Arai F, Hirao A. et al.
    • Journal Title

      Cell 118(2)

      Pages: 149-161

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590964
  • [Journal Article] Regulation of cell cycle in hematopoietic stem cells by the niche.2004

    • Author(s)
      Hirao A, et al.
    • Journal Title

      Cell Cycle 3

      Pages: 54-56

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207042
  • [Journal Article] Regulation of oxidative stress by ATM is required for the self-renewal of haematopoietic stem cells.2004

    • Author(s)
      Ito K, Hirao A. et al.
    • Journal Title

      Nature 431(7011)

      Pages: 997-1002

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590964
  • [Patent] 腫瘍治療用医薬組成物2024

    • Inventor(s)
      平尾敦、小林昌彦、YongWei Jing
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2024-017993
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-23K27437
  • [Patent] 腫瘍治療用医薬組成物2021

    • Inventor(s)
      1.平尾敦, Jing Y, 小林昌彦, 中田光俊
    • Industrial Property Rights Holder
      1.平尾敦, Jing Y, 小林昌彦, 中田光俊
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Patent] 腫瘍治療用医薬組成物2021

    • Inventor(s)
      1.平尾敦, Jing Y, 小林昌彦, 中田光俊
    • Industrial Property Rights Holder
      1.平尾敦, Jing Y, 小林昌彦, 中田光俊
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Patent] 1‐メチルニコチンアミドの測定方法及びニコチンアミド-N-メチル基転移酵素阻害剤のスクリーニング方法2020

    • Inventor(s)
      生越友樹、上野将也、平尾敦
    • Industrial Property Rights Holder
      生越友樹、上野将也、平尾敦
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-174186
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Patent] 脳腫瘍治療組成物2015

    • Inventor(s)
      中田光俊、平尾敦
    • Industrial Property Rights Holder
      中田光俊、平尾敦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-05-07
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] Cell fate decision by metabolic regulation in normal and malignant hematopoiesis2023

    • Author(s)
      Hirao A
    • Organizer
      Korea-Japan Blood and Vessel Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27437
  • [Presentation] Cell fate determination mediated by nutrient-derived metabolites in malignant progression.2023

    • Author(s)
      Asushi Hirao
    • Organizer
      2023 Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Presentation] Cell fate decision by metabolic regulation in normal and malignant hematopoiesis2023

    • Author(s)
      Hirao A
    • Organizer
      Korea-Japan Blood and Vessel Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18298
  • [Presentation] Metabolic Organelle Dynamics on Cell Fate Determination2023

    • Author(s)
      Hirao A
    • Organizer
      India-Japan Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27437
  • [Presentation] Cell fate determination mediated by nutrient-derived metabolites in malignant progression.2023

    • Author(s)
      HiraoA:
    • Organizer
      2023 Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Organelle Dynamics on Cell Fate Determination2023

    • Author(s)
      Hirao A
    • Organizer
      India-Japan Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18298
  • [Presentation] 栄養および免疫制御を介した造血幹細胞の発がん・老化,2022

    • Author(s)
      平尾敦
    • Organizer
      第8回がんと代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] 栄養および免疫制御を介した造血幹細胞の発がん・老化,2022

    • Author(s)
      平尾敦
    • Organizer
      第8回がんと代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Presentation] 栄養代謝による細胞運命決定とがん2021

    • Author(s)
      平尾敦
    • Organizer
      第94回日本生化学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Presentation] Cell fate determination mediated by nutrient-derived metabolites in tumor development and malignant progression.2021

    • Author(s)
      Atsushi Hirao
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Presentation] Cell fate decision by metabolic regulation in hematopoietic stem cell homeostasis and leukemogenesis.2021

    • Author(s)
      Atsushi Hirao
    • Organizer
      The 39th Sapporo International Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19502
  • [Presentation] 栄養代謝による細胞運命決定とがん2021

    • Author(s)
      平尾敦
    • Organizer
      第94回日本生化学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Cell fate determination mediated by nutrient-derived metabolites in tumor development and malignant progression.2021

    • Author(s)
      Atsushi Hirao
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Cell fate decision by metabolic regulation in hematopoietic stem cell homeostasis and leukemogenesis.2021

    • Author(s)
      Atsushi Hirao
    • Organizer
      The 39th Sapporo International Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Development of a novel approach inducing differentiation in LSCs by targeting FOXOs-downstream genes2020

    • Author(s)
      倉吉健太、上野将也、高瀬雄介、布施香子 大田久美子、田所優子、平尾敦
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Development of a novel approach inducing differentiation in leukemic stem cells by targeting FOXOs-downstream genes2020

    • Author(s)
      倉吉健太、上野将也、平尾敦
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Critical role of metabolic regulation in self-renewal of hematopoietic stem cells and leukemogenesis2020

    • Author(s)
      平尾敦
    • Organizer
      第82回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Investigation of the roles of OLIG2 in stemness property of glioblastoma2020

    • Author(s)
      小林昌彦、平尾敦
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019

    • Author(s)
      Hirao A
    • Organizer
      Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19585
  • [Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019

    • Author(s)
      Hirao A
    • Organizer
      2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Critical roles of gut microbiota in self-renewal of hematopoietic stem cells and leukemogenesis2019

    • Author(s)
      Hirao A
    • Organizer
      2nd Japan-German symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019

    • Author(s)
      Hirao A
    • Organizer
      Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] 栄養シグナルとステムネス ー造血幹細胞制御機構の解明から疾患の理解へー2019

    • Author(s)
      平尾敦
    • Organizer
      日本生化学会東北支部例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Critical regulation of metabolites for hematopoietic homeostasis and leukemogenesis2019

    • Author(s)
      平尾敦
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019

    • Author(s)
      Hirao A
    • Organizer
      2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019

    • Author(s)
      Hirao A
    • Organizer
      2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19585
  • [Presentation] Critical role of nutrient signals in hematopoietic stemness and malignancy2019

    • Author(s)
      平尾敦
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019

    • Author(s)
      Hirao A
    • Organizer
      Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] 幹細胞2019

    • Author(s)
      平尾敦
    • Organizer
      研修医のための血液学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01033
  • [Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018

    • Author(s)
      Hirao A
    • Organizer
      JSPS - National University of Singapore (NUS) 2nd Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Metabolic Control of Cancer Stemness.2018

    • Author(s)
      Hirao A
    • Organizer
      The 2nd NanoLSI Symposium in London Towards Establishment of New Research Field: Nanoprobe Life Science-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018

    • Author(s)
      Hirao A
    • Organizer
      JSPS - National University of Singapore (NUS) 2nd Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] Metabolic Control of Cancer Stemness2018

    • Author(s)
      Hirao A
    • Organizer
      The 2nd NanoLSI Symposium in London Towards Establishment of New Research Field: Nanoprobe Life Science-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2018

    • Author(s)
      Hirao A
    • Organizer
      International symposium on drug discovery (Joint symposium of Univ. of Tokyo and Novartis Institute)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19585
  • [Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018

    • Author(s)
      Hirao A
    • Organizer
      JSPS - National University of Singapore (NUS) 2nd Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Metabolic Control of Cancer Stemness.2018

    • Author(s)
      Hirao A
    • Organizer
      The 2nd NanoLSI Symposium in London
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19585
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2018

    • Author(s)
      Hirao A
    • Organizer
      International symposium on drug discovery (Joint symposium of Univ. of Tokyo and Novartis Institute)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis. International symposium on drug discovery2018

    • Author(s)
      Hirao A
    • Organizer
      Joint symposium of Univ. of Tokyo and Novartis Institute
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017

    • Author(s)
      平尾敦
    • Organizer
      第7回細胞再生医療学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017

    • Author(s)
      平尾敦
    • Organizer
      第7回細胞再生医療学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017

    • Author(s)
      Hirao A
    • Organizer
      The joint symposium on tumor microenvironemnt and precision medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017

    • Author(s)
      Hirao A
    • Organizer
      2017 Cancer Biology Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05638
  • [Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017

    • Author(s)
      Hirao A
    • Organizer
      The joint symposium on tumor microenvironemnt and precision medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017

    • Author(s)
      Hirao A
    • Organizer
      2017 Cancer Biology Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017

    • Author(s)
      平尾敦
    • Organizer
      第7回細胞再生医療学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017

    • Author(s)
      Hirao A
    • Organizer
      The joint symposium on tumor microenvironemnt and precision medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017

    • Author(s)
      Hirao A
    • Organizer
      2017 Cancer Biology Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] 既存薬による膠芽腫に対する新規化学療法2016

    • Author(s)
      中田光俊,董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
    • Organizer
      第34回日本脳腫瘍学会
    • Place of Presentation
      甲府、甲府富士屋ホテル
    • Year and Date
      2016-12-04
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2016

    • Author(s)
      Hirao A
    • Organizer
      46th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-11-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] 栄養シグナルと幹細胞制御2016

    • Author(s)
      平尾敦
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] 既存薬の応用による膠芽腫に対する新規化学療法2016

    • Author(s)
      中田光俊、董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
    • Organizer
      第75回日本脳神経外科学会総会
    • Place of Presentation
      福岡、福岡国際会議場・福岡サンパレス・マリンメッセ福岡
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016

    • Author(s)
      Hirao A
    • Organizer
      Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
    • Place of Presentation
      Urayasu, Chiba
    • Year and Date
      2016-07-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] Drug repositioning targeting glioma stem cells2016

    • Author(s)
      Nakada M, Dong Y, Kitabayashi Y, Sabit H, Furuta T, Hirao A
    • Organizer
      Society for Neuro-Onology 21st Annual Meeting 2016
    • Place of Presentation
      Scottsdale Fairmont Princess Hotel, Scottsdale, Arizona, USA
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] Molecular mechanism regulating stem cell properties mediated by nutrient signals.2016

    • Author(s)
      Hirao A
    • Organizer
      46th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-11-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2016

    • Author(s)
      Hirao A
    • Organizer
      46th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-11-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016

    • Author(s)
      Hirao A
    • Organizer
      Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
    • Place of Presentation
      Urayasu, Chiba
    • Year and Date
      2016-07-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] 栄養シグナルと幹細胞制御2016

    • Author(s)
      平尾敦
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016

    • Author(s)
      Hirao A
    • Organizer
      Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
    • Place of Presentation
      Urayasu, Chiba
    • Year and Date
      2016-07-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Screening of existing drugs to target glioma stem cells2016

    • Author(s)
      Nakada M, Dong Y, Kitabayashi Y, Sabit H, Furuta T, Hirao A
    • Organizer
      13th Asian Society for Neuro-Oncology (ASNO) Meeting
    • Place of Presentation
      Sheraton on the Park, Sydney, Australia
    • Year and Date
      2016-09-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] 栄養シグナルと幹細胞制御2016

    • Author(s)
      平尾敦
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01199
  • [Presentation] Stem cell regulation by nutrient signals2015

    • Author(s)
      Hirao A
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市、愛知県)
    • Year and Date
      2015-10-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Role of nutrient sensing signaling pathways in the maintenance of leukemia stem cells.2015

    • Author(s)
      Hirao A
    • Organizer
      SNUCRI CANCER SYMPOSIUM
    • Place of Presentation
      Kumho Hwasun Resort(Hwasun, Korea)
    • Year and Date
      2015-04-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] Existing approved drug with anti-glioma effect and drug safety test in vivo2015

    • Author(s)
      董宇, 北林朋宏, 古田拓也, 平尾敦, 中田光俊
    • Organizer
      第16回日本分子脳神経外科学会
    • Place of Presentation
      アクトシティ浜松コングレスセンター(浜松)
    • Year and Date
      2015-08-28
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2015

    • Author(s)
      Hirao A
    • Organizer
      International Society for Experimental Hematology(ISEH) 44th Annual Scientific Meeting
    • Place of Presentation
      京都国際会議場(京都市、京都府)
    • Year and Date
      2015-09-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02361
  • [Presentation] グリオーマ幹細胞を標的とした新規化学療法の開発2015

    • Author(s)
      中田光俊,董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
    • Organizer
      第74回日本脳神経外科学会総会
    • Place of Presentation
      ロントン札幌(札幌)
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] 造血・白血病幹細胞研究の現状と未来.2015

    • Author(s)
      平尾敦
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      ホテル金沢(金沢市、石川県)
    • Year and Date
      2015-10-16
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] フォークヘッド転写因子FOXOによる急性骨髄性白血病代謝調節機構2015

    • Author(s)
      大田久美子、布施香子、上野将也、河野晋、高橋智聡、平尾敦
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      金沢/石川県立音楽堂交流ホール
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-15K19548
  • [Presentation] Role of nutrient sensing signaling pathways in the maintenance of leukemia stem cells.2015

    • Author(s)
      Hirao A
    • Organizer
      SNUCRI CANCER SYMPOSIUM
    • Place of Presentation
      Kumho Hwasun Resort(Hwasun, Korea)
    • Year and Date
      2015-04-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2015

    • Author(s)
      Hirao A
    • Organizer
      International Society for Experimental Hematology(ISEH) 44th Annual Scientific Meeting
    • Place of Presentation
      京都国際会議場(京都市、京都府)
    • Year and Date
      2015-09-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509
  • [Presentation] Role of FOXO on metabolic regulation in acute myeloid leukemia2015

    • Author(s)
      Kumiko Ohta, Kyoko Fuse, Mayasa Ueno, Kohno, Takahashi and Atsushi Hirao
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋/名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K19548
  • [Presentation] 栄養センサーシグナルと幹細胞制御2013

    • Author(s)
      平尾敦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      SUCRI-KUCRI Joint Symposium
    • Place of Presentation
      Seoul National University (Korea)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670447
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      The 23th Hot Spring Harbor International Symposium
    • Place of Presentation
      Kyushu University(Fukuoka)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670447
  • [Presentation] 栄養センサーシグナルと幹細胞制御2013

    • Author(s)
      平尾敦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      The 23th Hot Spring Harbor International Symposium
    • Place of Presentation
      Kyushu University(Fukuoka)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] 栄養センサーシグナルと幹細胞制御2013

    • Author(s)
      平尾敦
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670447
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      SUCRI-KUCRI Joint Symposium
    • Place of Presentation
      Seoul National University (Korea)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      The 23th Hot Spring Harbor International Symposium
    • Place of Presentation
      Kyushu University(Fukuoka)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013

    • Author(s)
      Hirao A
    • Organizer
      SUCRI-KUCRI Joint Symposium
    • Place of Presentation
      Seoul National University (Korea)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2012

    • Author(s)
      Hirao A
    • Organizer
      New Frontiers of Metabolism Research in Biomedical Sciences
    • Place of Presentation
      東京大学(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] 栄養センサーシグナルとがん幹細胞2012

    • Author(s)
      平尾 敦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] The nutrient sensing signaling pathways in cancer2012

    • Author(s)
      平尾 敦
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2012-12-11
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] The nutrient sensing signaling pathways in cancer2012

    • Author(s)
      平尾 敦
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2012

    • Author(s)
      Hirao A
    • Organizer
      New Frontiers of Metabolism Research in Biomedical Sciences
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2012-09-27
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] 栄養センサーシグナルとがん幹細胞2012

    • Author(s)
      平尾 敦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌)
    • Year and Date
      2012-09-19
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011

    • Author(s)
      Hirao A
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011

    • Author(s)
      Hirao A
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県)(招待講演)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011

    • Author(s)
      Hirao A
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県)(招待講演)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] PI3K-AKTシグナルによるがん幹細胞制御機構の解明と治療戦略2011

    • Author(s)
      平尾敦
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      ホテル日航東京(東京)
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      G0 symposium
    • Place of Presentation
      沖縄科学技術大学院大学(Okinawa)(招待講演)
    • Year and Date
      2011-10-24
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] Role of PI3K-AKT signals inthe maintenance of stem cells innormal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Role of RI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      G0 symposium
    • Place of Presentation
      沖縄科学技術大学院大学(Okinawa)(招待講演)
    • Year and Date
      2011-10-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011

    • Author(s)
      Hirao A
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県)(招待講演)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] PI3K-AKTシグナルによるがん幹細胞制御機構の解明と治療戦略2011

    • Author(s)
      平尾敦
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      ホテル日航東京(東京)
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Molecular mechanismsregulating maintenance of leukemiastem cells by PI3K-AKT pathway2011

    • Author(s)
      Hirao A
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PUBLICLY-23130507
  • [Presentation] 白血病治療的抵抗性メカニズムと幹細胞2011

    • Author(s)
      平尾敦
    • Organizer
      北海道大学遺伝子病制御研究所共同研究集会
    • Place of Presentation
      北海道大学講堂(北海道)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      G0 symposium
    • Place of Presentation
      冲縄科学技術大学院大学(Okinawa)(招待講演)
    • Year and Date
      2011-10-24
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      G0 symposium
    • Place of Presentation
      OIST(沖縄)
    • Year and Date
      2011-10-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of PI3K-AKT signalingin the maintenance of stem cellproperties in normal hematopoiesisand leukemia2011

    • Author(s)
      Hirao A
    • Organizer
      G0 symposium
    • Place of Presentation
      OIST(沖縄)
    • Year and Date
      2011-10-24
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] 白血病治療抵抗性と幹細胞制御2011

    • Author(s)
      平尾敦
    • Organizer
      第16回分生研シンポジウム
    • Place of Presentation
      東京大学弥生講堂(東京)
    • Data Source
      KAKENHI-PROJECT-23650593
  • [Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      Tbkyo iPS/Stem cell symposium
    • Place of Presentation
      東京大学安田講堂(東京都)(招待講演)
    • Year and Date
      2010-11-24
    • Data Source
      KAKENHI-PROJECT-22650226
  • [Presentation] Roles of TGFβ/FoxO in the maintenance of leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      The 59th Fujihara Seminar, Molecularmechanisms of TGF-βsignaling anddisease
    • Place of Presentation
      グランドホテルニュー王子(北海道)
    • Year and Date
      2010-07-14
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Regulation of hematopoietic stem cell homeostasis and leukemia2010

    • Author(s)
      Hirao A
    • Organizer
      AACR
    • Place of Presentation
      Hilton Waikoloa Village(USA)
    • Year and Date
      2010-02-07
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 栄養代謝制御シグナルと造血幹細胞2010

    • Author(s)
      平尾敦
    • Organizer
      第31回日本炎症・再生医学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 寿命制御シグナルと造血幹細胞2010

    • Author(s)
      平尾敦
    • Organizer
      第10回日本抗加齢医学会総会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2010-06-11
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      Tokyo iPS/Stem cell symposium
    • Place of Presentation
      東京大学安田講堂(東京)
    • Year and Date
      2010-11-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Regulation of stem cell homeostasis and tumorigenesis2010

    • Author(s)
      Hirao A
    • Organizer
      BMB2010
    • Place of Presentation
      神戸国際会議場(兵庫)
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells, ESH-ICMLF Twelfth International Conference2010

    • Author(s)
      Hirao A
    • Organizer
      CHRONIC MYELOID LEUKAEMIA-Biological Basis of Therapy
    • Place of Presentation
      Washignton DC, USA
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 造血幹細胞および白血病幹細胞維持制御メカニズム2010

    • Author(s)
      平尾敦
    • Organizer
      日本顕微鏡学会
    • Place of Presentation
      金沢市ホール(石川)
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      Tokyo iPS/Stem cell symposium
    • Place of Presentation
      東京大学安田講堂(東京都) 招待講演
    • Year and Date
      2010-11-24
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 白血病幹細胞制御機構の解明と治療戦略2010

    • Author(s)
      平尾敦
    • Organizer
      第14回日本がん分子標的治療学会学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2010

    • Author(s)
      平尾敦
    • Organizer
      第9回日本再生医療学会
    • Place of Presentation
      広島国際会議場(広島)
    • Year and Date
      2010-03-19
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia st em cells.2010

    • Author(s)
      Hirao A
    • Organizer
      The 15th Japanese Foundation for Cancer ncer Chemotherapv(UFCR-ISCC)
    • Place of Presentation
      ホテル日航東京(東京都) 招待講演
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 幹細胞研究に基づいた脳腫瘍の発生・病態制御機構解明へのアプローチ2010

    • Author(s)
      平尾敦
    • Organizer
      第19回日本がん転移学会学術集会
    • Place of Presentation
      金沢市ホール(石川)
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      The 15th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy(JFCR-ISCC)
    • Place of Presentation
      ホテル日航東京(東京)
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Molecular mechanisms regulating self-renewal of glioma-initiating cells2010

    • Author(s)
      Hirao A
    • Organizer
      第69回日本癌学会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 腫瘍悪性進展制御と細胞分化2010

    • Author(s)
      平尾敦
    • Organizer
      第48回日本癌治療学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2010-10-27
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      ESH-ICMLF'Ttwelfth International Conference.CHRONIC MYELOID LEUKAEMIA
    • Place of Presentation
      Grand Hyatt'Washington DC(USA)(招待講演)
    • Data Source
      KAKENHI-PROJECT-22650226
  • [Presentation] Roles of TGFIβ/FoxO in the maintenance of leukemia stem cel is2010

    • Author(s)
      Hirao A
    • Organizer
      The 59th Fuiihara Seminar, Molecular mechanisms of TGF-β signaling and disease
    • Place of Presentation
      グランドホテルニュー王子(北海道) 招待講演
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of TGFβ/FoxO in the maintenance of leukemia stem celis2010

    • Author(s)
      Hirao A
    • Organizer
      The 59th Fujihara Seminar, Molecular mechanisms of TGF-B signaling and disease
    • Place of Presentation
      グランドホテルニュー王子(北海道)(招待講演)
    • Data Source
      KAKENHI-PROJECT-22650226
  • [Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells.2010

    • Author(s)
      Hirao A
    • Organizer
      The 15th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy(JFCR・ISCC)
    • Place of Presentation
      ホテル日航東京(東京都)(招待講演)
    • Data Source
      KAKENHI-PROJECT-22650226
  • [Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells2010

    • Author(s)
      Hirao A
    • Organizer
      ESH-ICMLF Twelfth International Conference, CHRONIC MYELOID LEUKAEMIA
    • Place of Presentation
      Grand Hyatt Washingt on DC (USA) 招待講演
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia.2009

    • Author(s)
      Hirao A
    • Organizer
      The 8th Japan-China Joint Conference for Cancer Research
    • Place of Presentation
      リーガロイヤルホテル大阪(大阪府)
    • Year and Date
      2009-10-05
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Roles of forkhead transcription factor Fox03a in normal hematopoiesis and leukemia.2009

    • Author(s)
      Hirao A
    • Organizer
      USA-Japan Cooperative Cancer Workshop 2009
    • Place of Presentation
      米国ハワイ
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009

    • Author(s)
      平尾敦
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] 寿命制御シグナルと幹細胞2009

    • Author(s)
      平尾敦
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia. The 4th International workshop on Cell Regulations in Division and Arrest2009

    • Author(s)
      Hirao A
    • Organizer
      Okinawa
    • Place of Presentation
      OISI(沖縄)
    • Year and Date
      2009-11-30
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 寿命制御シグナルと幹細胞2009

    • Author(s)
      平尾敦
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009

    • Author(s)
      平尾敦
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia2009

    • Author(s)
      Hirao A
    • Organizer
      The 8th Japan-China Joint Conference for Cancer Research
    • Place of Presentation
      リーガロイヤルホテル大阪(大阪)
    • Year and Date
      2009-10-05
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009

    • Author(s)
      平尾敦
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都府)
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvironmental factors2009

    • Author(s)
      平尾敦
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009

    • Author(s)
      平尾敦
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia.2009

    • Author(s)
      平尾敦
    • Organizer
      The 8th Japan-China Joint Conference for Cancer Research
    • Place of Presentation
      リーガロイヤルホテル大阪(大阪府)
    • Year and Date
      2009-10-05
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvirc nmental factors2009

    • Author(s)
      平尾敦
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009

    • Author(s)
      平尾敦
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸国際会議場(兵庫)
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009

    • Author(s)
      平尾敦
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都府)
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] 寿命制御シグナルと幹細胞2009

    • Author(s)
      平尾敦
    • Organizer
      第51回日本老年医学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21390290
  • [Presentation] Roles of forkhead transcription factor Fox03a in normal hema topoiesis and leukemia2009

    • Author(s)
      Hirao A
    • Organizer
      USA-Japan Cooperative Cancer Workshop
    • Place of Presentation
      米国ハワイ
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvironmental factors2009

    • Author(s)
      平尾敦
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Effects of aging-or senescence-related factors on stem cell function and tissue homeostasis in vivo2008

    • Author(s)
      Hirao A
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Stemness in normal and malignant tissues2008

    • Author(s)
      Hirao A
    • Organizer
      Mechanisms of Early Differentiation, Summer School
    • Place of Presentation
      ドイツ(Barsinghausen)
    • Year and Date
      2008-09-03
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] Prospective identification of leukemic stem cells by promoter activity of nucleostemin gene2008

    • Author(s)
      Naka K, Ohmura M, Muraguchi T, Hoshii T, Hirao A.
    • Organizer
      6^<th> International Society of Stem Cell Research
    • Place of Presentation
      Philadelphia, PA, USA
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Sternness in normal and malignant tissues.2008

    • Author(s)
      Hirao A
    • Organizer
      第67回日本癌学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-27
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Mechanisms of Early Differentiation2008

    • Author(s)
      Hirao A, Stemness in normal, malignant tissues
    • Organizer
      Summer School
    • Place of Presentation
      Barsinghausen, Germany
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Effects of aging- or senescence-related factors on stem cell function and tissue homeostasis in vivo.2008

    • Author(s)
      Hirao A
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Stemness in normal and malignant tissues2008

    • Author(s)
      Hirao A
    • Organizer
      第67回日本癌学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-27
    • Data Source
      KAKENHI-PROJECT-20013016
  • [Presentation] 正常および腫瘍組織における幹細胞システム2008

    • Author(s)
      平尾敦
    • Organizer
      第45回日本婦人科腫瘍学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2008-11-22
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Stemness in normal and malignant tissues2008

    • Author(s)
      Hirao A
    • Organizer
      第67回日本癌学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-27
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Nucleosteminプロモーター活性による白血病幹細胞の同定2008

    • Author(s)
      仲一仁, 大村昌子, 石原正彦、宮地宏昌、須田年生、平尾敦
    • Organizer
      第67回日本癌学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-27
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Nucleostemin-GFPレポーターシステムによる白血病幹細胞の同定2008

    • Author(s)
      仲一仁, 大村昌子, 村口輝行, 星居孝之, 須田年生, 平尾敦
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Stemness in normal and malignant tissues2008

    • Author(s)
      Hirao A.
    • Organizer
      The third International workshop on Cell Regulations in Division and Arrest
    • Place of Presentation
      Okinawa
    • Year and Date
      2008-04-09
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Identification of tumor-initiating cells by using Nucleostemin promoter activity2008

    • Author(s)
      Naka K, Ohmura M, Muraguchi T, Hoshii T, Hirao A.
    • Organizer
      Keystone Symposia, Tumor suppressor and stem cell biology
    • Place of Presentation
      Vancouver
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Nucleostemin-GFPレポーターシステムによる白血病幹細胞の同定2008

    • Author(s)
      仲一仁, 大村昌子, 村口輝行, 星居孝之, 平尾敦
    • Organizer
      第6回幹細胞シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 36th Congress of2008

    • Author(s)
      HIrao A, Stemness in normal, malignant tissues
    • Organizer
      the International Society of Oncology & BioMarkers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-10-07
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Effects of aging-or senescence-related factors on stem cell function and tissue homeostasis in vivo2008

    • Author(s)
      Hirao A.
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Sternness in normal and malignant tissues.2008

    • Author(s)
      Hirao A
    • Organizer
      Mechanisms of Early Differentiation, Summer School
    • Place of Presentation
      ドイツ
    • Year and Date
      2008-09-03
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] The 5^<th> International Society2007

    • Author(s)
      Naka K, Ohmura M, Arai F, Suda T, Hirao A.
    • Organizer
      of Stem Cell Research
    • Place of Presentation
      Cairns,Australia
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] NucleosteminプロモーターGFP トランスジェニックマウスによる造血幹細胞標識システムの樹立2007

    • Author(s)
      仲一仁, 大村昌子, 野口亜希, 石原正彦、宮地宏昌、須田年生, 平尾敦
    • Organizer
      第66回日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Nucleosteminの発現による組織幹細胞の可視化と同定2007

    • Author(s)
      大村昌子、仲一仁、木下雅史、玉瀬玲、新井文用、永松剛、田久保圭誉、照田展大、須田年生、平尾敦
    • Organizer
      第5回幹細胞シンポジウム
    • Place of Presentation
      淡路島
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 造血幹細胞の自己複製と老化2007

    • Author(s)
      平尾敦
    • Organizer
      第69回日本血液学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-07
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] The 49^<th> American Society2007

    • Author(s)
      Naka K, Ohmura M, Suda T, Hirao A
    • Organizer
      of Hematology Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 幹細胞制御における組織間共通性2007

    • Author(s)
      平尾敦
    • Organizer
      第10回日本組織工学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-08
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Regulation of stem cell self-renewal by aging related genes2007

    • Author(s)
      Hirao A
    • Organizer
      The second International workshop on Cell Regulations in Division and Arrest
    • Place of Presentation
      Okinawa
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Stemness genes in cancer2007

    • Author(s)
      平尾敦
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] The 19^<th> Naito Conference2006

    • Author(s)
      Hirao A
    • Organizer
      Molecular Basis for Maintenance and Differentiation of Stem Cells[II]Nov
    • Place of Presentation
      Kanagawa
    • Year and Date
      2006-01-05
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Regulation of stem cell self-renewal by aging-related genes2006

    • Author(s)
      Hirao A
    • Organizer
      35^<th> Annual Scientific Meeting International Society for Experimental Hematology
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2006-09-26
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] Regulation of stem cell self-renewal by tumor related genes2006

    • Author(s)
      Hirao A
    • Organizer
      Sixteenth International Symposium of the Hiroshima Cancer Seminar
    • Place of Presentation
      Hiroshima
    • Year and Date
      2006-10-22
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 幹細胞自己複製制御と老化・寿命制御の共通性2006

    • Author(s)
      平尾敦
    • Organizer
      老年医学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2006-06-08
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 核小体分子Nucleosteminによる生殖幹細胞制御機構2006

    • Author(s)
      大村昌子、新井文用、仲一仁、田久保圭誉、東真樹、須田年生、平尾敦
    • Organizer
      第4回幹細胞シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2006-05-20
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] ROS regulation and self-renewal capacity2006

    • Author(s)
      Hirao A
    • Organizer
      International Symposium on Gas Biology : Hematopoietic stem cells
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-06-27
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] 組織幹細胞マーキング法の開発2006

    • Author(s)
      大村昌子、仲一仁、新井文用、木下雅史、玉瀬玲、松岡佐保子、伊藤圭介、宮本佳奈、田久保圭誉、須田年生、平尾敦
    • Organizer
      第68回日本血液学会
    • Place of Presentation
      福岡
    • Year and Date
      2006-10-08
    • Data Source
      KAKENHI-PROJECT-18390281
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic and leukemia stem cells.

    • Author(s)
      Hirao A
    • Organizer
      SNUCRI CANCER SYMPOSIUM
    • Place of Presentation
      韓国
    • Year and Date
      2014-04-16 – 2014-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.

    • Author(s)
      Hirao A
    • Organizer
      2015 US-Japan meeting on malignant hematopoiesis and stem cells.
    • Place of Presentation
      米国
    • Year and Date
      2015-03-16 – 2015-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670447
  • [Presentation] The nutrient sensing signaling pathways in the hematopoietic and leukemia stem cells.

    • Author(s)
      Hirao A
    • Organizer
      SNUCRI CANCER SYMPOSIUM
    • Place of Presentation
      韓国
    • Year and Date
      2014-04-16 – 2014-04-19
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.

    • Author(s)
      Hirao A
    • Organizer
      2015 US-Japan meeting on malignant hematopoiesis and stem cells.
    • Place of Presentation
      米国
    • Year and Date
      2015-03-16 – 2015-03-17
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.

    • Author(s)
      平尾 敦
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.

    • Author(s)
      Hirao A
    • Organizer
      2015 US-Japan meeting on malignant hematopoiesis and stem cells
    • Place of Presentation
      米国
    • Year and Date
      2015-03-16 – 2015-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] Screening of existing approved drugs for inhibiting glioma stem cell proliferation

    • Author(s)
      董宇, 中田光俊, 北林朋宏, 古田拓也, 平尾敦, 林裕
    • Organizer
      第15回日本分子脳神経外科学会
    • Place of Presentation
      大手門パルズ(山形)
    • Year and Date
      2014-09-25 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] The nutrient sensing signaling in the cancer stem cells.

    • Author(s)
      平尾 敦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240119
  • [Presentation] グリオーマ幹細胞に対して抗腫瘍効果を有する既存医薬品の探索

    • Author(s)
      中田光俊,董宇,北林朋宏,古田拓也,宮下勝吉,木下雅史,平尾敦,林裕
    • Organizer
      第32回日本脳腫瘍学会
    • Place of Presentation
      シェラトン・グランデ・トーキョーベイ・ホテル(千葉)
    • Year and Date
      2014-11-30 – 2014-12-02
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.

    • Author(s)
      平尾 敦
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • [Presentation] ドラッグリポジショニングを指向したグリオーマ幹細胞に対する既存薬剤スクリーニング

    • Author(s)
      中田光俊,董宇,北林朋宏,古田拓也,平尾敦,林裕
    • Organizer
      第73回日本脳神経外科学会総会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-26293322
  • [Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.

    • Author(s)
      平尾 敦
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670447
  • [Presentation] The nutrient sensing signaling in the cancer stem cells.

    • Author(s)
      平尾 敦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130705
  • []

  • []

  • 1.  OKAMOTO Yasuhiro (30398002)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  OIKE Yuichi (90312321)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KAWANO Yoshifumi (20260680)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TADOKORO Yuko (00447343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  SUDA Toshio (60118453)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  OHBO Kazuyuki (70250751)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  Nakada Mitsutoshi (20334774)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 8.  Kobayashi Masahiko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  SUEMATSU Makoto (00206385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  SAITOU Masao (70302239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SOGA Tomoyoshi (60338217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  TANAKA Hirotoshi (00171794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  SHINKODA Yuichi (50457652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Ohta Kumiko (30416177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  MINAMOTO Toshinari (50239323)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  足立 健 (50231931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大根田 修 (30311872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  高倉 伸幸 (80291954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  加藤 将夫 (30251440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  平石 哲也 (80515734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大石 誠 (00422593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  棗田 学 (00515728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  清水 宏 (40608767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  増尾 友佑 (90708140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Ueno Masaya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 26.  DONG Yu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 27.  FURUTA Takuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 28.  SABIT Hemragul
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 29.  KITABAYASHI Tomohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 30.  BABA Tomohisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  原 英二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  菊田 順一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  田沼 延公
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  山田 秀和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  笠原 敦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 36.  河本 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  筋野 智久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  細江 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  小松 則夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  斉藤 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  檜井 栄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  町田 雪乃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  河本 新平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  堂本 貴寛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  中川 直
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  山西 吉典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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