Suzuki Takayoshi 鈴木孝禎

… Alternative Names

SUZUKI Takayoshi 鈴木孝禎

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Researcher Number	90372838
Other IDs
External Links
Affiliation (Current)	2025: 大阪大学, 産業科学研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 大阪大学, 産業科学研究所, 教授 2011 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2018: 京都府立医科大学, 医学部, 教授 2017: 京都府立医科大学, 医学系研究科, 教授 2015 – 2017: 京都府立医科大学, 大学院医学研究科, 教授 … More 2015: 京都府立医科大学, 医学研究科医薬品化学講座, 教授 2014: 京都府立医科大学, 医学部, 教授 2012: 京都府立医科大学, 大学院・医学研究科, 教授 2011 – 2012: 名古屋市立大学, 大学院・薬学研究科, 講師 2008: 名古屋市立大学, 大学院・薬学研究科, 講師 2007: 名古屋市立大学, 大学院・薬学研究科, 助教 2005 – 2006: 名古屋市立大学, 大学院薬学研究科, 助手 2004 – 2005: 名古屋市立大学, 大学院・薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry / Drug development chemistry / Transition State Control / Chemical pharmacy Except Principal Investigator Drug development chemistry / Basic Section 59010:Rehabilitation science-related / Hematology … More / Medium-sized Section 58:Society medicine, nursing, and related fields / Urology / Digestive surgery / Chemical biology / Tumor biology / Tumor therapeutics / 医薬分子機能学 Less
Keywords	Principal Investigator 阻害薬 / エピジェネティクス / ヒストン脱アセチル化酵素 / 酵素 / がん / 創薬 / 分子設計 / 脱アセチル化酵素 / トリアゾール / クリックケミストリー … More / 阻害剤 / 有機化学 / 後遺症 / 重症化 / 薬剤耐性 / 抗ウイルス薬 / 複合体 / キメラ分子 / 長鎖ノンコーディングRNA / SIRT / ドラッグデリバリー / ヒストン脱メチル化酵素 / C-H活性化反応 / ホモロジーモデル / SIRT7 / SIRT2 / 神経変性疾患 / HDAC2 / in situクリックケミストリー / 医薬品 / 標的誘導型合成 / 薬学 / アイソザイム選択性 / 速度論的阻害薬 / 遷移状態 / メチル化 / 活性化剤 / 脱メチル化酵素 / 遺伝性疾患 / アイソザイム / リシン脱アセチル化酵素 / アルキン / アジド / アイソフォーム / リガンド / タンパク質 / 水素結合 / 癌 / 発現抑制 / 遺伝子 … More Except Principal Investigator エピゲノム / エピジェネティクス / 簡易検査 / 薬剤剤型 / 嚥下障害 / ヒストン修飾 / HTLV-1 / ATL / 活性酸素種 / 有機化学 / 脳機能マッピング / 脳機能画像 / 嚥下音 / polypharmacy / 嚥下聴診器 / brain mapping / 家族性大腸腺腫症 / リ・フラウメニ症候群 / がん体質診断 / テーラーメイドがん予防 / 先制医療 / サーチュイン / 白血病 / Sirtuin / NCL1 / 薬剤耐性 / ヒストン脱メチル化 / 膀胱癌臨床検体 / アポトーシス / オートファジー / 膀胱癌 / LSD1 / 癌 / ピロール-イミダゾールポリアミド / ピロール・イミダゾールポリアミド / エピゲノム制御 / DNA配列認識 / ヒストンメチル化 / 発現制御 / 核酸化学 / ピロール・イミダゾール・ポリアミド / 遺伝子変異 / 癌治療 / 膠芽腫 / 治療 / グリオブラストーマ / 抗がん剤耐性 / 分子標的治療 / tocopherol / edaravone / catechin / fullerene / pharmacophore / active oxygen species / radical scavenger / oxyl radical / 神経毒性 / スピントラップ剤 / ESR / オキシラジカル / トコフェロール / エダラボン / カテキン / フラーレン / ファーマコフォア / ラジカル消去剤 / オキシルラジカル / SIRT1 / 酸化還元 / 細胞・組織 / 分析科学 / ストレス / 薬学 / 生物活性物質 / チューブリン / 制がん剤 / ヒストン脱アセチル化酵素阻害剤 / ヒストン脱アセチル化酵素阻害薬 / ヒストン脱メチル化酵素阻害剤 / 創薬分子設計 / 遺伝子発現制御 / タンパク質 / 脳神経疾患 / 酵素反応 / 化学プローブ / ドナー化合物 / パーオキシナイトライト / 一酸化窒素 / 酸化ストレス Less

A New Therapeutic Strategy for Pharmaceutical Dosage Forms and Drug Delivery
- Principal Investigator
  
  山脇正永
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokyo Medical and Dental University
Development of chimera molecules targeting epigenetic complexesPrincipal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Development of a new generation of antiviral agents that are effective against drug-resistant viruses and prevent serious illness and sequelae.Principal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Development of innovative drug candidates by target guided synthesisPrincipal Investigator
- Principal Investigator
  
  Suzuki Takayoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Research on best dosage forms for deglutition disorders
- Principal Investigator
  
  Yamawaki Masanaga
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokyo Medical and Dental University
Medicinal chemistry targeting epigenetic long noncoding RNAsPrincipal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Osaka University
Medicinal chemistry targeting epigenetic long noncoding RNAsPrincipal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Osaka University
Tailor-maid cancer prevention towards the era of preemptive medicine.
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Design, synthesis and biological activity of SIRT7 inhibitorsPrincipal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Development of inhibitors that stablize the transition state of enzymatic reactionsPrincipal Investigator
- Principal Investigator
  
  Suzuki Takayoshi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Transition State Control
- Research Institution
  Osaka University
  Kyoto Prefectural University of Medicine
Development of platform for cancer epigenetic therapy by region-specific inhibition of epigenomic alteration
- Principal Investigator
  
  Kaneda Atsushi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Elucidation of epigenome-mediated proliferation mechanism in bladder cancer and development of therapy with novel inhibitors
- Principal Investigator
  
  Iida Keitaro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Nagoya City University
Novel small-molecule sirtuin inhibitors induce cell apoptic death in leukemia cells
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
ＣＨ活性化反応を利用したエピジェネティクス制御化合物の創製Principal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Discovery of demethylase/deacetylase modulators towards therapy for hereditary diseasesPrincipal Investigator
- Principal Investigator
  
  Suzuki Takayoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of a novel tumor-associated protein in gliomagenesis and chemicals targeting its function.
- Principal Investigator
  
  Kondo Yutaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya City University
Selective modification of histone methylation using DNA binding-small molecules
- Principal Investigator
  
  Shinohara Ken-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Chiba University
ＳＩＲＴ７阻害薬の創製研究Principal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Development of drug-resistance-overcoming agents targeting histone demethylase JARID1A
- Principal Investigator
  
  Tamio Mizukami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Novel small-molecule SIRT1 inhibitors induce cell death in leukaemia cells
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
Discovery of drug candidates by using in situ click chemistryPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takayoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
ＨＤＡＣ２選択的阻害薬の創製Principal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Basic and applied research of CH-O interactionPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takayoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto Prefectural University of Medicine
Oxidative stress imaging in organelle by novel TEMPO derivatives
- Principal Investigator
  
  NAKAGAWA Hidehiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
Development of drug candidates that epigenetically regulate gene expression
- Principal Investigator
  
  MIYATA Naoki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
Oxidative degeneration of neurodegenerative disease-related protein and reactive nitrogen oxide stress
- Principal Investigator
  
  NAKAGAWA Hidehiko
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
ヒストンのアセチル化により遺伝子発現を制御するリガンドの創製と医薬への応用Principal Investigator
- Principal Investigator
  
  鈴木孝禎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
Development of novel oxyl-radical quenching pharmacophores as drug candidates
- Principal Investigator
  
  MIYATA Naoki
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Nagoya City University

[Book] Approaching Complex Diseases2020
- Author(s)
  Kozako T, Itoh Y, Honda S, Suzuki T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19H01079
[Book] Chemical Epigenetics2020
- Author(s)
  Suzuki T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19H01079
[Book] 次世代エピジェネティックドラッグ開発の最前線遺伝子医学MOOK 25 エピジェネティクスと病気2013
- Author(s)
  鈴木孝禎
- Data Source
  KAKENHI-PROJECT-23659012
[Book] エピジェネティクスと病気2013
- Author(s)
  鈴木孝禎
- Total Pages
  280
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23659012
[Journal Article] Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice2024
- Author(s)
  Li Haiyan、Kawatake-Kuno Ayako、Inaba Hiromichi、Miyake Yuka、Itoh Yukihiro、Ueki Takatoshi、Oishi Naoya、Murai Toshiya、Suzuki Takayoshi、Uchida Shusaku
- Journal Title
  
  Neuron
  
  Volume: 112 Issue: 5 Pages: 00934-0
- DOI
  10.1016/j.neuron.2023.12.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18186, KAKENHI-PROJECT-21K07593, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-23K21413, KAKENHI-PROJECT-23K24789
[Journal Article] Role of plant homeodomain finger protein 8 in P19 embryonic carcinoma cells revealed by genome editing and specific inhibitor2024
- Author(s)
  Doi Shusuke、Suzuki Takayoshi、Soeda Shuhei、Miyata Naoki、Inazu Tetsuya
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101670-101670
- DOI
  10.1016/j.bbrep.2024.101670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07235, KAKENHI-PROJECT-21H04795
[Journal Article] Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells2024
- Author(s)
  Ota Y, Itoh Y, Takada Y, Yamashita Y, Hu C, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 100 Pages: 117632-117632
- DOI
  10.1016/j.bmc.2024.117632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795
[Journal Article] A Structure–Activity Relationship Study of SNAIL1 Peptides as Inhibitors of Lysine-Specific Demethylase 12024
- Author(s)
  Takada Yuri、Adachi Kyohei、Fujinaga Yuka、Yamashita Yasunobu、Itoh Yukihiro、Suzuki Takayoshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 72 Issue: 2 Pages: 155-160
- DOI
  10.1248/cpb.c23-00671
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2024-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-21H04795
[Journal Article] Structural optimization of a lysine demethylase 5 inhibitor for improvement of its cellular activity2024
- Author(s)
  Terao Mitsuhiro、Yamashita Yasunobu、Takada Yuri、Itoh Yukihiro、Suzuki Takayoshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 98 Pages: 117579-117579
- DOI
  10.1016/j.bmc.2023.117579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18186, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-21H04795
[Journal Article] Identification of a Histone Deacetylase 8 Inhibitor through Drug Screenings Based on Machine Learning2024
- Author(s)
  Nurani Atika、Yamashita Yasunobu、Taki Yuuki、Takada Yuri、Itoh Yukihiro、Suzuki Takayoshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 72 Issue: 2 Pages: 173-178
- DOI
  10.1248/cpb.c23-00577
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2024-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-21H04795
[Journal Article] Discovery of selective histone deacetylase 1 and 2 inhibitors: screening of a focused library constructed by click chemistry, kinetic binding analysis, and biological evaluation2023
- Author(s)
  Itoh Y, Zhan P, Tojo T, Jaikhan P, Ota Y, Suzuki M, Li Y, Hui Z, Moriyama Y, Takada Y, Yamashita Y, Oba M, Uchida S, Masuda M, Ito S, Sowa Y, Sakai T, Suzuki T
- Journal Title
  
  J Med Chem
  
  Volume: 66 Issue: 22 Pages: 15171-15188
- DOI
  10.1021/acs.jmedchem.3c01095
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-20K15959, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-23K23487
[Journal Article] SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer’s Disease2023
- Author(s)
  Sola-Sevilla Noemi、Mesa-Lombardo Alberto、Aleixo Mikel、Exp?sito Sara、Diaz-Perdig?n Teresa、Azqueta Amaya、Zamani Farzad、Suzuki Takayoshi、Maioli Silvia、Eroli Francesca、Matton Anna、Ram?rez Maria J.、Solas Maite、Tordera Rosa M.、Mart?n Eduardo D.、Puerta Elena
- Journal Title
  
  Journal of Neuroimmune Pharmacology
  
  Volume: 18 Issue: 3 Pages: 529-550
- DOI
  10.1007/s11481-023-10084-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Origin of the kinetic <scp>HDAC2</scp>‐selectivity of an <scp>HDAC</scp> inhibitor2023
- Author(s)
  Mishima Hirokazu、Itoh Yukihiro、Kurohara Takashi、Suzuki Takayoshi、Asada Naoya、Kusakabe Ken‐ichi、Okamoto Yuko
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 44 Issue: 18 Pages: 1604-1609
- DOI
  10.1002/jcc.27111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Pharmacological inhibition of KDM1A/LSD1 enhances estrogen receptor beta-mediated tumor suppression in ovarian cancer2023
- Author(s)
  Venkata Prabhakar Pitta、Jayamohan Sridharan、He Yi、Alejo Salvador、Johnson Jessica D.、Palacios Bridgitte E.、Pratap Uday P.、Chen Yihong、Liu Zexuan、Zou Yi、Lai Zhao、Suzuki Takayoshi、、Vadlamudi Ratna K.、Sareddy Gangadhara R.
- Journal Title
  
  Cancer Letters
  
  Volume: 575 Pages: 216383-216383
- DOI
  10.1016/j.canlet.2023.216383
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Catalytic asymmetric synthesis of (?)-arctigenin using a chiral Ir complex2023
- Author(s)
  Jiang Rui、Zhou Da-Yang、Asano Kaori、Suzuki Takayoshi、Suzuki Takeyuki
- Journal Title
  
  Tetrahedron
  
  Volume: 133 Pages: 133287-133287
- DOI
  10.1016/j.tet.2023.133287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20K05494
[Journal Article] Evolution of Slow-Binding Inhibitors Targeting Histone Deacetylase Isoforms2023
- Author(s)
  Mukherjee Anirban、Zamani Farzad、Suzuki Takayoshi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 66 Issue: 17 Pages: 11672-11700
- DOI
  10.1021/acs.jmedchem.3c01160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma2023
- Author(s)
  Alejo Salvador、Suzuki Takayoshi、Sareddy Gangadhara R et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 44 Issue: 7 Pages: 1249-1261
- DOI
  10.1093/neuonc/noad018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action2023
- Author(s)
  Kitao Yuki、Saito Tadataka、Watanabe Satoshi、Ohe Yasuhiro、Takahashi Koichi、Akaki Tatsuo、Adachi Tsuyoshi、Doi Satoki、Yamanaka Kenji、Murai Yasutaka、Oba Makoto、Suzuki Takayoshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 80 Pages: 129110-129110
- DOI
  10.1016/j.bmcl.2022.129110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients2022
- Author(s)
  Mure Kanae、Ishikawa Hideki、Mutoh Michihiro、Horinaka Mano、Otani Takahiro et al.
- Journal Title
  
  Cancer Research Communications
  
  Volume: 2 Issue: 6 Pages: 483-488
- DOI
  10.1158/2767-9764.crc-22-0088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11791, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC)2022
- Author(s)
  Jiranan Chotitumnavee, Yasunobu Yamashita, Yukari Takahashi, Yuri Takada, Tetsuya Iida, Makoto Oba, Yukihiro Itoh, Takayoshi Suzuki
- Journal Title
  
  Chem. Commun.
  
  Volume: 58 Issue: 29 Pages: 5051-5056
- DOI
  10.1039/d2cc00272h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-21K20719
[Journal Article] Cancer-cell-selective targeting by arylcyclopropylamine-vorinostat conjugates2022
- Author(s)
  Ota Y, Itoh Y, Kurohara T, Singh R, Elboray EE, Hu C, Zamani F, Mukherjee A, Takada Y, Yamashita Y, Morita M, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 13 Issue: 10 Pages: 1568-1573
- DOI
  10.1021/acsmedchemlett.2c00126
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20F40107, KAKENHI-PROJECT-21K20719
[Journal Article] Novel histone modifications in microglia derived from a mouse model of chronic pain2022
- Author(s)
  Zhang Ping、Guergues Jennifer、Alleyne Amy R.、Cirino Thomas J.、Nadeau Owen、Figueroa Ariana M.、Stacy Heather M.、Suzuki Takayoshi、McLaughlin Jay P.、Stevens Stanley M.、Liu Bin
- Journal Title
  
  PROTEOMICS
  
  Volume: - Issue: 9 Pages: 2100137-2100137
- DOI
  10.1002/pmic.202100137
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Journal Article] Using α- and β-Epimerizations of cis-2,3-Bis(hydroxymethyl)-γ-butyrolactone for the Synthesis of Both Enantiomers of Enterolactone2022
- Author(s)
  Jiang Rui、Ismiyarto、Abe Tsukasa、Zhou Da-Yang、Asano Kaori、Suzuki Takayoshi、Sasai Hiroaki、Suzuki Takeyuki
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: - Issue: 8 Pages: 5051-5056
- DOI
  10.1021/acs.joc.1c02801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20K05494
[Journal Article] A Novel HDAC1-Selective Inhibitor Attenuates Autoimmune Arthritis by Inhibiting Inflammatory Cytokine Production2022
- Author(s)
  Wei Zhe, Naomi Hoshina, Yukihiro Itoh, Toshifumi Tojo, Takayoshi Suzuki, Koji Hase*, Daisuke Takahashi* (*equal correspondence)
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 9 Pages: 1364-1372
- DOI
  10.1248/bpb.b22-00321
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07552, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-21H04795
[Journal Article] Medicinal Chemistry Research on Targeting Epigenetic Complexes2022
- Author(s)
  Yuri Takada, Yasunobu Yamashita, Yukihiro Itoh, Takayoshi Suzuki
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 80 Issue: 7 Pages: 664-675
- DOI
  10.5059/yukigoseikyokaishi.80.664
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2022-07-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-21K20719
[Journal Article] Recent progress on small molecules targeting epigenetic complexes2022
- Author(s)
  Itoh Yukihiro、Takada Yuri、Yamashita Yasunobu、Suzuki Takayoshi
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 67 Pages: 102130-102130
- DOI
  10.1016/j.cbpa.2022.102130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-21K20719
[Journal Article] Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial2021
- Author(s)
  Ishikawa H、Mutoh M、Sato Y、Doyama H、Tajika M、Tanaka S、Horimatsu T、Takeuchi Y、Kashida H、Tashiro J、Ezoe Y、Nakajima T、Ikematsu H、Hori S、Suzuki S、Otani T、Takayama T、Ohda Y、Mure K、Wakabayashi K、Sakai T
- Journal Title
  
  The Lancet Gastroenterology & Hepatology
  
  Volume: － Issue: 6 Pages: 474-481
- DOI
  10.1016/s2468-1253(21)00018-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03054, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21K11791
[Journal Article] KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer2021
- Author(s)
  Zhou M, Venkat P P, Viswanadhapalli S, Palacios B, Alejo S, Chen Y, He Y, Pratap U, Zou Y, Lai Z, Suzuki T, Brenner A, Tekmal R R, Vadlamudi R K, Sareddy G R
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 185 Issue: 2 Pages: 343-357
- DOI
  10.1007/s10549-020-05963-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5?C Degraders2021
- Author(s)
  Iida Tetsuya、Itoh Yukihiro、Takahashi Yukari、Yamashita Yasunobu、Kurohara Takashi、Miyake Yuka、Oba Makoto、Suzuki Takayoshi
- Journal Title
  
  ChemMedChem
  
  Volume: - Issue: 10 Pages: 1609-1618
- DOI
  10.1002/cmdc.202000933
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H05295, KAKENHI-PROJECT-19H01079
[Journal Article] Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach2021
- Author(s)
  Prakash Muthuraj、Itoh Yukihiro、Fujiwara Yoshie、Takahashi Yukari、Takada Yuri、Mellini Paolo、Elboray Elghareeb E.、Terao Mitsuhiro、Yamashita Yasunobu、Yamamoto Chika、Yamaguchi Takao、Kotoku Masayuki、Kitao Yuki、Singh Ritesh、Roy Rohini、Obika Satoshi、Oba Makoto、Wang Dan Ohtan、Suzuki Takayoshi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 21 Pages: 15810-15824
- DOI
  10.1021/acs.jmedchem.1c01107
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20K21488, KAKENHI-PROJECT-21H02580
[Journal Article] Catalytic enantioselective intramolecular Tishchenko reaction of meso-dialdehyde: synthesis of (S)-cedarmycins2021
- Author(s)
  Ismiyarto、Kishi Nobuki、Adachi Yuki、Jiang Rui、Doi Takahiro、Zhou Da-Yang、Asano Kaori、Obora Yasushi、Suzuki Takayoshi、Sasai Hiroaki、Suzuki Takeyuki
- Journal Title
  
  RSC Advances
  
  Volume: 11 Issue: 19 Pages: 11606-11609
- DOI
  10.1039/d1ra00915j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05494, KAKENHI-PROJECT-19H01079
[Journal Article] Ca2+‐activated K+ channel KCa1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models2021
- Author(s)
  Ohya Susumu、Kajikuri Junko、Endo Kyoko、Kito Hiroaki、Elboray Elghareeb E.、Suzuki Takayoshi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 9 Pages: 3769-3783
- DOI
  10.1111/cas.15046
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20K07071, KAKENHI-PROJECT-21K06600
[Journal Article] Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors2021
- Author(s)
  Gediya P, Vyas V K, Carafa V, Sitwala N, Torre L D, Poziello A, Kurohara, T Suzuki T, Raghuraman V, Suthindhiran K, Ghosh D, Bhatia D, Altucci L, Manjunath D
- Journal Title
  
  Ghate Bioorg Chem
  
  Volume: 110 Pages: 104801-104819
- DOI
  10.1016/j.bioorg.2021.104801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-21H04795
[Journal Article] Synthetic RNA Modulators in Drug Discovery2021
- Author(s)
  Zamani Farzad、Suzuki Takayoshi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 11 Pages: 7110-7155
- DOI
  10.1021/acs.jmedchem.1c00154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20F40107
[Journal Article] Identification of Novel Histone Deacetylase 6‐Selective Inhibitors Bearing 3,3,3‐Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group2021
- Author(s)
  Kurohara Takashi、Tanaka Keita、Takahashi Daisuke、Ueda Satoshi、Yamashita Yasunobu、Takada Yuri、Takeshima Hirokazu、Yu Shengwang、Itoh Yukihiro、Hase Koji、Suzuki Takayoshi
- Journal Title
  
  ChemBioChem
  
  Volume: 22 Issue: 22 Pages: 3158-3163
- DOI
  10.1002/cbic.202100255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-20K07552
[Journal Article] N<sup>+</sup>-C-H…O Hydrogen Bonds in Protein-Ligand Complexes and their Application to Drug Design2020
- Author(s)
  Itoh Y, Kurohara T, Suzuki T
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 78 Issue: 12 Pages: 1151-1162
- DOI
  10.5059/yukigoseikyokaishi.78.1151
- NAID
  130007951812
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2020-12-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] Metalloprotein-catalyzed click reaction for in situ generation of a potent inhibitor.2020
- Author(s)
  Miyake Y, Itoh Y, Suzuma Y, Kodama H, Kurohara T, Yamashita Y, Narozny R, Hanatani Y, Uchida S, Suzuki T
- Journal Title
  
  ACS Catal
  
  Volume: 10 Issue: 10 Pages: 5383-5392
- DOI
  10.1021/acscatal.0c00369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] Downregulation of the Ca2+-activated K+ channel KCa3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist2020
- Author(s)
  Kito Hiroaki、Morihiro Haruka、Sakakibara Yuka、Endo Kyoko、Kajikuri Junko、Suzuki Takayoshi、Ohya Susumu
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 319 Issue: 2 Pages: C345-C358
- DOI
  10.1152/ajpcell.00587.2019
- NAID
  130007902073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0218, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-16KT0060
[Journal Article] Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma2020
- Author(s)
  Okabe Atsushi, Huang Kie Kyon, Matsusaka Keisuke, Fukuyo Masaki, Xing Manjie, Ong Xuewen, Hoshii Takayuki, Usui Genki, Seki Motoaki, Mano Yasunobu, Rahmutulla Bahityar, Kanda Teru, Suzuki Takayoshi, Rha Sun Young, Ushiku Tetsuo, Fukayama Masashi, Tan Patrick, Kaneda Atsushi
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 9 Pages: 919-930
- DOI
  10.1038/s41588-020-0665-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K09184, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03690, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-18J00861, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-19K22399, KAKENHI-PROJECT-19K16101
[Journal Article] Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor2020
- Author(s)
  Yeong Keng Yoon、Khaw Kooi Yeong、Takahashi Yukari、Itoh Yukihiro、Murugaiyah Vikneswaran、Suzuki Takayoshi
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 94 Pages: 103403-103403
- DOI
  10.1016/j.bioorg.2019.103403
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-19H01079
[Journal Article] エピゲノム修飾薬2020
- Author(s)
  鈴木孝禎
- Journal Title
  
  遺伝子医学
  
  Volume: 31 Pages: 74-79
- Data Source
  KAKENHI-PROJECT-16KT0060
[Journal Article] Selective lysine-specific demethylase 1 inhibitor, NCL1, could cause testicular toxicity via the regulation of apoptosis2020
- Author(s)
  Nozaki S, Naiki T, Naiki-Ito A, Iwatsuki S, Takeda T, Etani T, Nagai T, Iida K, Kato H, Suzuki T, Takahashi S, Umemoto Y, Yasui T.
- Journal Title
  
  Andrology
  
  Volume: 8 Issue: 6 Pages: 1895-1906
- DOI
  10.1111/andr.12846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07486, KAKENHI-PROJECT-19K07509, KAKENHI-PROJECT-20K09531, KAKENHI-PROJECT-20K09561, KAKENHI-PROJECT-20K16225, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-18K16706
[Journal Article] LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia2020
- Author(s)
  Tatsumi G, Kawahara M, Yamamoto R, Hishizawa M, Kito K, Suzuki T, Takaori-Kondo A, Andoh A
- Journal Title
  
  Leukemia.
  
  Volume: 34 Issue: 3 Pages: 746-758
- DOI
  10.1038/s41375-019-0614-6
- NAID
  120006768263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08002, KAKENHI-PROJECT-19K08811, KAKENHI-PROJECT-19H01079
[Journal Article] Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols2019
- Author(s)
  Ogihara Shusuke、Komatsu Toru、Itoh Yukihiro、Miyake Yuka、Suzuki Takayoshi、Yanagi Kouichi、Kimura Yusuke、Ueno Tasuku、Hanaoka Kenjiro、Kojima Hirotatsu、Okabe Takayoshi、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 1 Pages: 21-26
- DOI
  10.1021/jacs.9b08698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-17K19477
[Journal Article] Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model2019
- Author(s)
  Diaz-Perdigon Teresa、Belloch Francisco B.、Ricobaraza Ana、Elboray Elghareeb E.、Suzuki Takayoshi、Tordera Rosa M.、Puerta Elena
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 45 Issue: 2 Pages: 347-357
- DOI
  10.1038/s41386-019-0503-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-17F17115
[Journal Article] Genome-wide ChIP-seq data with a transcriptome analysis reveals the groups of genes regulated by histone demethylase LSD1 inhibition in esophageal squamous cell carcinoma cells.2019
- Author(s)
  Hoshino I, Takahashi M, Akutsu Y, Murakami K, Matsumoto Y, Suito H, Sekino N, Komatsu A, Iida K, Suzuki T, Inoue I, Ishige F, Iwatate Y, Matsubara H.
- Journal Title
  
  Oncol Lett.
  
  Volume: 18 Pages: 872-881
- DOI
  10.3892/ol.2019.10350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-17K10616
[Journal Article] Possible Contribution of Inflammation-Associated Hypoxia to Increased K2P5.1 K+ Channel Expression in CD4+ T Cells of the Mouse Model for Inflammatory Bowel Disease2019
- Author(s)
  Endo Kyoko、Kito Hiroaki、Tanaka Ryo、Kajikuri Junko、Tanaka Satoshi、Elboray Elghareeb E.、Suzuki Takayoshi、Ohya Susumu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 1 Pages: 38-38
- DOI
  10.3390/ijms21010038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-18KK0218, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-17F17115, KAKENHI-PROJECT-17J09558
[Journal Article] Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the “Selectivity Pocket”, Substrate-Binding Site, and NAD+-Binding Site2019
- Author(s)
  Mellini Paolo、Itoh Yukihiro、Elboray Elghareeb E.、Tsumoto Hiroki、Li Ying、Suzuki Miki、Takahashi Yukari、Tojo Toshifumi、Kurohara Takashi、Miyake Yuka、Miura Yuri、Kitao Yuki、Kotoku Masayuki、Iida Tetsuya、Suzuki Takayoshi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 12 Pages: 5844-5862
- DOI
  10.1021/acs.jmedchem.9b00255
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-17F17115
[Journal Article] Design, Synthesis, and Biological Evaluation of a Conjugate of 5-Fluorouracil and an LSD1 Inhibitor2019
- Author(s)
  Yosuke Ota, Arisa Nakamura, Elghareeb E. Elboray, Yukihiro Itoh and Takayoshi Suzuki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 3 Pages: 192-195
- DOI
  10.1248/cpb.c18-00577
- NAID
  130007606081
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14874, KAKENHI-PROJECT-17F17115
[Journal Article] HDAC8 inhibition ameliorates pulmonary fibrosis2019
- Author(s)
  Shigeki Saito, Yan Zhuang, Takayoshi Suzuki, Yosuke Ota, Marjorie E. Bateman, Ala L. Alkhatib, Gilbert F. Morris and Joseph A. Lasky
- Journal Title
  
  American Journal of Physiology Lung Cellular and Molecular Physiology
  
  Volume: 316 Issue: 1 Pages: L175-L186
- DOI
  10.1152/ajplung.00551.2017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Journal Article] Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines.2018
- Author(s)
  Kozako, T., Mellini, P., Ohsugi, T., Aikawa, A., Uchida, Y. I., Honda, S. I., Suzuki, T.
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 791-791
- DOI
  10.1186/s12885-018-4710-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-16K09863
[Journal Article] サーチュイン阻害剤による白血病細胞のオートファジー2018
- Author(s)
  小迫知弘、鈴木孝禎
- Journal Title
  
  BIO Clinica
  
  Volume: 33 Pages: 68-73
- Data Source
  KAKENHI-PROJECT-16K09863
[Journal Article] Structural basis of HDAC8 selective inhibition2018
- Author(s)
  M. Marek, T. B. Shaik, T. Heimburg, A. Chakrabarti, J. Lancelot, E. Ramos-Morales, C. Da Veiga, D. Kalinin, J. Melesina, D. Robaa, K. Schmidtkunz, T. Suzuki, R. Holl, E. Ennifar, R. J. Pierce, M. Jung, W. Sippl and C. Romier
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 61 Issue: 22 Pages: 10000-10016
- DOI
  10.1021/acs.jmedchem.8b01087
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Journal Article] GPX2 promotes development of bladder cancer with squamous cell differentiation through the control of apoptosis.2018
- Author(s)
  Naiki T, Naiki-Ito A, Iida K, Etani T, Kato H, Suzuki S, Yamashita Y, Kawai N, Yasui T, Takahashi S.
- Journal Title
  
  Oncotarget
  
  Volume: 22 Issue: 22 Pages: 15847-15859
- DOI
  10.18632/oncotarget.24627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11153, KAKENHI-PROJECT-15K08352, KAKENHI-PROJECT-16K20154, KAKENHI-PROJECT-17K11155, KAKENHI-PROJECT-17K15666, KAKENHI-PROJECT-18K16705
[Journal Article] HDAC8 regulates neural differentiation through embryoid body formation in P19 cells2018
- Author(s)
  Syouichi Katayama, Atsushi Morii, Juliet O. Makanga, Takayoshi Suzuki, Naoki Miyata and Tetsuya Inazu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 498 Issue: 1 Pages: 45-51
- DOI
  10.1016/j.bbrc.2018.02.195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0060
[Journal Article] Computational analysis for selectivity of histone deacetylase inhibitor by replica-exchange umbrella sampling molecular dynamics simulations2018
- Author(s)
  Tsukamoto Shuichiro、Sakae Yoshitake、Itoh Yukihiro、Suzuki Takayoshi、Okamoto Yuko
- Journal Title
  
  The Journal of Chemical Physics
  
  Volume: 148 Issue: 12 Pages: 125102-125102
- DOI
  10.1063/1.5019209
- NAID
  120006545081
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25102009, KAKENHI-PROJECT-25247071, KAKENHI-PROJECT-16KT0060
[Journal Article] SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action2017
- Author(s)
  Mercedes Erburu, Irene Munoz-Cobo, Teresa Diaz-Perdigon, Paolo Mellini, Takayoshi Suzuki, Elena Puerta, Rosa M. Tordera
- Journal Title
  
  Neuropharmacology
  
  Volume: 117 Pages: 195-208
- DOI
  10.1016/j.neuropharm.2017.01.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04779
[Journal Article] “Drug” Discovery with the Help of Organic Chemistry2017
- Author(s)
  Yukihiro Itoh, Takayoshi Suzuki
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 137 Issue: 3 Pages: 283-292
- DOI
  10.1248/yakushi.16-00231-1
- NAID
  130005396859
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2017-03-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14982, KAKENHI-PROJECT-26870495
[Journal Article] CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene.2017
- Author(s)
  Uchida S, Teubner BJ, Hevi C, Hara K, Kobayashi A, Dave RM, Shintaku T, Jaikhan P, Yamagata H, Suzuki T, Watanabe Y, Zakharenko SS, Shumyatsky GP.
- Journal Title
  
  Cell Rep
  
  Volume: 18 Issue: 2 Pages: 352-366
- DOI
  10.1016/j.celrep.2016.12.052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-16K10189
[Journal Article] Medicinal Chemistry Insights into Novel HDAC Inhibitors: An Updated Patent Review (2012-2016)2017
- Author(s)
  Peng Zhan, Xueshun Wang, Xinyong Liu, Takayoshi Suzuki
- Journal Title
  
  Recent Patents Anticancer Drug Discovery
  
  Volume: 12 Issue: 1 Pages: 16-34
- DOI
  10.2174/1574892811666161101102842
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Journal Article] Synthesis of Pyrrole-Imidazole Polyamide Oligomers Based on a Copper-Catalyzed Cross-Coupling Strategy.2017
- Author(s)
  Shiga N, Takayanagi S, Muramoto R, Murakami T, Qin R, Suzuki Y, Shinohara K, Kaneda A, Nemoto T.
- Journal Title
  
  Bioorg Med Chem Lett,
  
  Volume: 27 Issue: 10 Pages: 2197-2200
- DOI
  10.1016/j.bmcl.2017.03.052
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350977, KAKENHI-PROJECT-17K01959, KAKENHI-PROJECT-16K15608
[Journal Article] C-H Activation Enables Rapid Structure-Activity Relationship Study of Arylcylclopropyl amines for Potent and Selective LSD1 Inhibitors2016
- Author(s)
  Miyamura, S.; Araki, M;; Ota, Y; Itoh, Y; Yasuda, S; Masada, M; Taniguchi, T; Sowa, Y; Sakai, T; Suzuki, T; Itami, K.; Yamaguchi, J.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 Issue: 36 Pages: 8576-8585
- DOI
  10.1039/c6ob01483f
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04148, KAKENHI-PROJECT-15K14982
[Journal Article] Identification of SNAIL1 Peptide-Based Irreversible Lysine Specific Demethylase 1-Selective Inactivators2016
- Author(s)
  Yukihiro Itoh, Keisuke Aihara, Paolo Mellini, Toshifumi Tojo, Yosuke Ota, Hiroki Tsumoto, Viswas Raja Solomon, Peng Zhan, Miki Suzuki, Daisuke Ogasawara, Akira Shigenaga, Tsubasa Inokuma, Hidehiko Nakagawa, Naoki Miyata, Tamio Mizukami, Akira Otaka, Takayoshi Suzuki.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 59 Issue: 4 Pages: 1531-1544
- DOI
  10.1021/acs.jmedchem.5b01323
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982, KAKENHI-PROJECT-14F04779, KAKENHI-PROJECT-14J07568
[Journal Article] Platinum-Catalyzed Friedel-Crafts-Type C–H Coupling–Allylic Amination Cascade to Synthesize 3,4-Fused Tricyclic Indoles2016
- Author(s)
  Yuta Suzuki, Yuito Tanaka, Shun-ichi Nakano, Kousuke Dodo, Natsumi Yoda, Ken-ichi Shinohara, Kazuko Kita, Atushi Kaneda, Mikiko Sodeoka, Yasumasa Hamada, and Tetsuhiro Nemoto
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 22 Issue: 13 Pages: 4418-4421
- DOI
  10.1002/chem.201600375
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07850, KAKENHI-PROJECT-26350977, KAKENHI-PROJECT-14J02661, KAKENHI-PLANNED-26110004
[Journal Article] Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide2016
- Author(s)
  Taeko Kakizawa, Tamio Mizukami, Yukihiro Itoh, Makoto Hasegawa, Ryuzo Sasaki, Takayoshi Suzuki
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 26 Issue: 4 Pages: 1193-1195
- DOI
  10.1016/j.bmcl.2016.01.036
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982, KAKENHI-PROJECT-26460159
[Journal Article] Strategies for the Discovery of Target-specific or Isoform-selective Modulators2015
- Author(s)
  Peng Zhan, Yukihiro Itoh, Takayoshi Suzuki, Xinyong Liu
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 58 Issue: 19 Pages: 7611-7633
- DOI
  10.1021/acs.jmedchem.5b00229
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Journal Article] Mutational landscape and clonal architecture in grade II and III gliomas2015
- Author(s)
  Suzuki H, Aoki K, Natsume A, Ogawa S. et al.
- Journal Title
  
  Nat Genet.
  
  Volume: 47 Issue: 5 Pages: 458-468
- DOI
  10.1038/ng.3273
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22134006, KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24390341, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15K19964, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26640088, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25861268, KAKENHI-PROJECT-25290048
[Journal Article] Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.2015
- Author(s)
  5.Ichimura N, Shinjo K, An B, Shimizu Y, Yamao K, Ohka F, Katsushima K, Hatanaka A, Tojo M, Yamamoto E, Suzuki H, Ueda M, Kondo Y
- Journal Title
  
  Cancer Prev Res (Phila)
  
  Volume: 10 Issue: 8 Pages: 702-11
- DOI
  10.1158/1940-6207.capr-14-0306
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640088, KAKENHI-PROJECT-25290048
[Journal Article] Medicinal chemistry insights in the discovery of novel lysine-specific demethylase 1 inhibitors2015
- Author(s)
  Xueshun Wang, Boshi Huang, Takayoshi Suzuki, Xinyong Liu, Peng Zhan
- Journal Title
  
  Epigenomics
  
  Volume: 7 Issue: 8 Pages: 1379-1396
- DOI
  10.2217/epi.15.86
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Journal Article] Identification of Jumonji AT-Rich Interactive Domain 1A Inhibitors and Their Effect on Cancer Cells.2015
- Author(s)
  Itoh Y, Sawada H, Suzuki M, Tojo T, Sasaki R, Hasegawa M, Mizukami T, Suzuki T
- Journal Title
  
  ACS Med Chem Lett.
  
  Volume: 6 Issue: 6 Pages: 665-670
- DOI
  10.1021/acsmedchemlett.5b00083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640093
[Journal Article] Target-guided Synthesis: Medicinal Chemistry Strategy to Allow Target Enzymes Themselves to Synthesize their Own Inhibitors2014
- Author(s)
  Yukihiro Itoh, Naoki Miyata, Takayoshi Suzuki
- Journal Title
  
  J. Syn. Org. Chem. Jpn.
  
  Volume: 72 Pages: 702-716
- NAID
  130004548618
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689007
[Journal Article] Recent advances in the structure-based rational design of TNKSIs.2014
- Author(s)
  Zhan P, Song Y, Itoh Y, Suzuki T, Liu X.
- Journal Title
  
  Mol Biosyst
  
  Volume: 10 Issue: 11 Pages: 2783-2799
- DOI
  10.1039/c4mb00385c
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12F02418
[Journal Article] Anticancer agents targeted to sirtuins.2014
- Author(s)
  Kozako T, Suzuki T, Yoshimitsu M, Arima N, Honda S, Soeda S.
- Journal Title
  
  Molecules
  
  Volume: 19 Issue: 12 Pages: 20295-313
- DOI
  10.3390/molecules191220295
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] Identification of Novel SIRT2-Selective Inhibitors Using a Click Chemistry Approach2014
- Author(s)
  109. Prima R. Tatum, Hideyuki Sawada, Yosuke Ota, Yukihiro Itoh, Peng Zhan, Naoya Ieda, Hidehiko Nakagawa, Naoki Miyata, Takayoshi Suzuki.
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 24 Issue: 8 Pages: 1871-1874
- DOI
  10.1016/j.bmcl.2014.03.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007
[Journal Article] Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-Selective Inhibitors.2014
- Author(s)
  Suzuki T, Muto N, Bando M, Itoh Y, Masaki A, Ri M, Ota Y, Nakagawa H, Iida S, Shirahige K, Miyata N.
- Journal Title
  
  ChemMedChem.
  
  Volume: 9 Issue: 3 Pages: 657-664
- DOI
  10.1002/cmdc.201300414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221009, KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007, KAKENHI-PROJECT-25290065
[Journal Article] Small-molecular modulators of cancer-related epigenetic mechanisms2013
- Author(s)
  Yukihiro Itoh , Takayoshi Suzuki and Naoki Miyata
- Journal Title
  
  Mol. Biosyst.
  
  Volume: 9 Issue: 5 Pages: 873-896
- DOI
  10.1039/c3mb25410k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007
[Journal Article] Effects of exogenous interleukin-7 on CD8(+) T-cell survival and function in human T-cell lymphotropic virus type 1 infection.2013
- Author(s)
  White Y, Yoshimitsu M, Kozako T, Matsushita K, Koriyama C, Uozumi K, Suzuki S, Kofune H, Arima N.
- Journal Title
  
  Leukemia and Lymphoma.
  
  Volume: 54 Issue: 10 Pages: 2243-2250
- DOI
  10.3109/10428194.2013.772174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300356, KAKENHI-PROJECT-23591398, KAKENHI-PROJECT-24591413
[Journal Article] Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly2013
- Author(s)
  98. Takayoshi Suzuki, Yuki Kasuya, Yukihiro Itoh, Yosuke Ota, Peng Zhan, Kaori Asamitsu, Hidehiko Nakagawa, Takashi Okamoto and Naoki Miyata.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e68669-e68669
- DOI
  10.1371/journal.pone.0068669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007
[Journal Article] Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries2012
- Author(s)
  Takayoshi Suzuki, Yosuke Ota, Masaki Ri, Masashige Bando, Aogu Gotoh, Yukihiro Itoh, Hiroki Tsumoto, Prima R. Tatum, Tamio Mizukami, Hidehiko Nakagawa, Shinsuke Iida, Ryuzo Ueda, Katsuhiko Shirahige, and Naoki Miyata.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 55 Issue: 22 Pages: 9562-9575
- DOI
  10.1021/jm300837y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10F00812, KAKENHI-PROJECT-22221009, KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007, KAKENHI-PROJECT-221S0001
[Journal Article] Novel bisbenzimide-nitroxides for nuclear redox imaging in living cells2012
- Author(s)
  池田麻美子、中川秀彦, 他2名
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 22 Issue: 5 Pages: 1949-1952
- DOI
  10.1016/j.bmcl.2012.01.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08121, KAKENHI-PROJECT-22590103
[Journal Article] Lysine demethylases inhibitors2011
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  J.Med.Chem.
  
  Volume: 54 Issue: 24 Pages: 8236-8250
- DOI
  10.1021/jm201048w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Lysine demethylases inhibitors2011
- Author(s)
  Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  J. Med. Chem.
  
  Volume: 54 Pages: 8236-8250
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] An Unexpected Example of Copper-Mediated In Situ Click Chemistry2010
- Author(s)
  Takayoshi Suzuki, Yosuke Ota, Yuki Kasuya, Motoh Mutsuga, Yoko Kawamura, Hiroki Tsumoto, Hidehiko Nakagawa, M. G. Finn, Naoki Miyata
- Journal Title
  
  Angew. Chem. Int. Ed. Engl.
  
  Volume: 49 Pages: 6817-6820
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, Synthesis, Enzyme-inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors2010
- Author(s)
  Shohei Hamada, Takayoshi Suzuki, Koshiki Mino, Koichi Koseki, Felix Oehme, Ingo Flamme, Hiroki Ozasa, Yukihiro Itoh, Daisuke Ogasawara, Haruka Komaarashi, Aiko Katoh, Hiroki Tsumoto, Hidehiko Nakagawa, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami, Naoki
- Journal Title
  
  J. Med. Chem.
  
  Volume: 53 Pages: 5629-5638
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors2010
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 20 Pages: 1124-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, Synthesis, Enzyme-inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors2010
- Author(s)
  Shohei Hamada, Takayoshi Suzuki, Koshiki Mino, Koichi Koseki, Felix Oehme, Ingo Flamme, Hiroki Ozasa, Yukihiro Itoh, Daisuke Ogasawara, Haruka Komaarashi, Aiko Katoh, Hiroki Tsumoto, Hidehiko Nakagawa, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami, Naoki Miyata
- Journal Title
  
  J.Med.Chem. 53
  
  Pages: 5629-5638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Development of a DNA-binding TEMPO derivative for evaluation of nuclear oxidative stress and its application in living cells2010
- Author(s)
  Mamiko Ikeda, Hidehiko Nakagawa, Shizuka Ban, Hiroki Tsumoto, Takayoshi Suzuki, and Naoki Miyata
- Journal Title
  
  Free Radic. Biol. Med
  
  Volume: 49 Issue: 11 Pages: 1792-1797
- DOI
  10.1016/j.freeradbiomed.2010.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590103
[Journal Article] An Unexpected Example of Copper-Mediated In Situ Click Chemistry2010
- Author(s)
  Takayoshi Suzuki, Yosuke Ota, Yuki Kasuya, Motoh Mutsuga, Yoko Kawamura, Hiroki Tsumoto, Hidehiko Nakagawa, M.G.Finn, Naoki Miyata
- Journal Title
  
  Angew.Chem.Int.Ed.Engl. 49
  
  Pages: 6817-6820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] An Unexpected Example of Copper-Mediated In Situ Click Chemistry2010
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Angew.Chem.Int.Ed.Engl.
  
  Volume: 49 Pages: 6817-6820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Identification of Cell-Active Lysine Specific Demethylase 1-Selective Inhibitors2009
- Author(s)
  Rie Ueda, Takayoshi Suzuki, Koshiki Mino, Hiroki Tsumoto, Hidehiko Nakagawa, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami, Naoki Miyata
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 131 Pages: 17536-17537
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine2009
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Bioorg.Med.Chem.Lett. 19
  
  Pages: 5670-5672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, Synthesis, and Biological Activity of Boronic acid-Based Histone Deacetylase Inhibitors2009
- Author(s)
  Nobuaki Suzuki, Takayoshi Suzuki, Yosuke Ota, Tatsuya Nakano, Masaaki Kurihara, Haruhiro Okuda, Takao Yamori, Hiroki Tsumoto, Hidehiko Nakagawa, Naoki Miyata
- Journal Title
  
  J. Med. Chem.
  
  Volume: 52 Pages: 2909-2922
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Inhibition of Human Sirtuins by In Situ Generation of an Acetylated Lysine-ADP-ribose Conjugate2009
- Author(s)
  Tomomi Asaba, Takayoshi Suzuki, Rie Ueda, Hiroki Tsumoto, Hidehiko Nakagawa, Naoki Miyata
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 31 Pages: 6989-6996
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Inhibition of Human Sirtuins by In Situ Generation of an Acetylated Lysine-ADP-ribose Conjugate2009
- Author(s)
  Tomomi Asaba, Takayoshi Suzuki, Rie Ueda, Hiroki Tsumoto, Hidehiko Nakagawa, Naoki Miyata
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 6989-6996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, synthesis, enzyme inhibition, and tumor cell growth inhibition of 2-anilinobenzamide derivatives as SIRT1 inhibitors2009
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 5900-5905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Identification of Cell-Active Lysine Specific Demethylase 1-Selective Inhibitors2009
- Author(s)
  Rie Ueda, Takayoshi Suzuki, Koshiki Mino, Hiroki Tsumoto, Hidehiko Nakagawa, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami, Naoki Miyata
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 17536-17537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Non-Hydroxamate Histone Deacetylase Inhibitors2009
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Frontiers in Medicinal Chemistry 4
  
  Pages: 619-641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, Synthesis, and Biological Activity of Boronic acid-Based Histone Deacetylase Inhibitors2009
- Author(s)
  Nobuaki Suzuki
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2909-2922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Design, Synthesis, and Biological Activity of Boronic acid-Based Histone Deacetylase Inhibitors2009
- Author(s)
  Nobuaki Suzuki, Takayoshi Suzuki, Yosuke Ota, Tatsuya Nakano, Masaaki Kurihara, Haruhiro Okuda, Takao Yamori, Hiroki Tsumoto, Hidehiko Nakagawa, Naoki Miyata
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2909-2922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390034
[Journal Article] Photoactivatable HNO-releasing compounds using the retro-Diels-Alder reaction2008
- Author(s)
  Yusuke Adachi, Hidehiko Nakagawa, Kazuya Matsuo, Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  Chem. Commun
  
  Pages: 5149-5151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590089
[Journal Article] Novel membrane-localizing TEMPO derivatives for measurement of cellular oxidative stress at the cell membrane2007
- Author(s)
  Shizuka Ban, Hidehiko Nakagawa, Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  Bioorg. Med. Chem. Lett 17
  
  Pages: 1451-1454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590089
[Journal Article] Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor2007
- Author(s)
  Takayoshi Suzuki et al.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 17
  
  Pages: 1558-1561
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] New Series of Antiprion Compounds : Pyrazolone Derivatives Have the Potent Activity of Inhibiting Protease-Resistant Prion Protein Accumulation2007
- Author(s)
  Ayako Kimata, Hidehiko Nakagawa, Ryo Ohyama, Tomoko Fukuuchi, Shigeru Ohta, Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  J. Med. Chem 50
  
  Pages: 5053-5056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590089
[Journal Article] Novel mitochondria-localizing TEMPO derivative for measurement of cellular oxidative stress in mitochondria, Bioorg2007
- Author(s)
  Shizuka Ban, Hidehiko Nakagawa, Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  Med. Chem. Lett 17
  
  Pages: 2055-2058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590089
[Journal Article] Highly Potent and Selective Histone Deacetylase 6 Inhibitors Desigened Based on a Small-molecular Substrate2006
- Author(s)
  Takayoshi Suzuki et al.
- Journal Title
  
  Journal of Medicinal Chemistry 49
  
  Pages: 4809-4812
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Epigenetic Control Using Natural Products and Synthetic Molecules2006
- Author(s)
  Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  Current Medicinal Chemistry 13
  
  Pages: 935-958
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Rational Design of Non-hydroxamate Histone Deacetylase Inhibitors2006
- Author(s)
  Takayoshi Suzuki, Naoki Miyata
- Journal Title
  
  Mini Reviews in Medicinal Chemistry 6
  
  Pages: 515-526
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] 2-Anilinobenzamides as SIRT inhibitors2006
- Author(s)
  Takayoshi Suzuki et al.
- Journal Title
  
  ChemMedChem 1
  
  Pages: 1059-1062
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] 癌の分子標的治療薬の開発:非ヒドロキサム酸系ヒストン脱アセチル化酵素阻害薬の設計、合成と生物活性評価2005
- Author(s)
  鈴木孝禎
- Journal Title
  
  有機合成化学協会誌 63
  
  Pages: 1004-1015
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Photoinduced Nitric Oxide Release from Nitrobenzene Derivatives2005
- Author(s)
  Takayoshi Suzuki ら
- Journal Title
  
  J.Am.Chem.Soc. 127(33)
  
  Pages: 11720-11726
- Data Source
  KAKENHI-PROJECT-14370763
[Journal Article] Photoinduced Nitric Oxide Release from Nitrobenzene Derivatives2005
- Author(s)
  Suzuki, T., Nagae, O., Kato, Y., Nakagawa, H., et al.
- Journal Title
  
  J.Am.Chem.Soc. 127(33)
  
  Pages: 11720-11726
- Data Source
  KAKENHI-PROJECT-17590089
[Journal Article] Design and synthesis of non-hydroxamate histone deacetylase inhibitors : identification of a selective histone acetylating agent2005
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Bioorganic and Medicinal Chemistry 13
  
  Pages: 4332-4342
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Photoinduced Nitric Oxide Release from Nitrobenzene Derivatives2005
- Author(s)
  Takayoshi Suzukiら
- Journal Title
  
  J. Am. Chem. Soc. 127(33)
  
  Pages: 11720-11726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370763
[Journal Article] Design and synthesis of non-hydroxamate histone deacetylase inhibitors; identification of a selective histone acetylating agent2005
- Author(s)
  Takayoshi Suzuki ら
- Journal Title
  
  Bioorganic & Medicinal Chemistry 13
  
  Pages: 4332-4342
- Data Source
  KAKENHI-PROJECT-14370763
[Journal Article] ヒストン脱アセチル化酵素阻害剤開発の最前線2005
- Author(s)
  鈴木孝禎
- Journal Title
  
  ファルマシア 41
  
  Pages: 523-527
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Photoinduced Nitric Oxide Release from Nitrobenzene Derivatives2005
- Author(s)
  Takayoshi Suzuki et al.
- Journal Title
  
  J.Am.Chem.Soc. 127(33)
  
  Pages: 11720-11726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370763
[Journal Article] Novel Inhibitors of Human Histone Deacetylases: Design, Synthesis, Enzyme Inhibition, and Cancer Cell Growth Inhibition of SAHA-Based Non-hydroxamates2005
- Author(s)
  Takayoshi Suzuki ら
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 1019-1032
- Data Source
  KAKENHI-PROJECT-14370763
[Journal Article] Non-hydroxamate Histone Deacetylase Inhibitors2005
- Author(s)
  Takayoshi Suzuki
- Journal Title
  
  Curent Medicinal Chemistry 12
  
  Pages: 2867-2880
- Data Source
  KAKENHI-PROJECT-17790092
[Journal Article] Photoinduced Nitric Oxide Release from Nitrobenzene Derivatives2005
- Author(s)
  Takayoshi Suzuki, Osamu Nagae, Yuka Kato, Hidehiko Nakagawa, Kiyoshi Fukuhara, Naoki Miyata
- Journal Title
  
  J. Am. Chem. Soc 127
  
  Pages: 11720-11726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590089
[Patent] 炎症性腸疾患処置剤2020
- Inventor(s)
  長谷耕二、高橋大輔、鈴木孝禎、黒原崇、上田聡、田中啓太
- Industrial Property Rights Holder
  長谷耕二、高橋大輔、鈴木孝禎、黒原崇、上田聡、田中啓太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-064635
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16KT0060
[Patent] ヒストン脱アセチル化酵素阻害剤2018
- Inventor(s)
  鈴木孝禎、伊藤幸裕、東條敏史、内田周作
- Industrial Property Rights Holder
  鈴木孝禎、伊藤幸裕、東條敏史、内田周作
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-008464
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16KT0060
[Patent] γターン構造を有する化合物及びそれを用いたLSD1阻害剤2016
- Inventor(s)
  伊丹健一郎、山口潤一郎、荒木未紗保、鈴木孝禎ら
- Industrial Property Rights Holder
  伊丹健一郎、山口潤一郎、荒木未紗保、鈴木孝禎ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-065756
- Filing Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K14982
[Patent] 遷移金属触媒反応を利用した 3,4 位中員環縮環 3-アルキリデンインドリン類、および 3,4 位中員環縮インドール類の合成法2016
- Inventor(s)
  根本哲宏、濱田康正、鈴木雄太、仲野駿一、篠原憲一、金田篤志、他
- Industrial Property Rights Holder
  根本哲宏、濱田康正、鈴木雄太、仲野駿一、篠原憲一、金田篤志、他
- Industrial Property Rights Type
  特許
- Filing Date
  2016-08-12
- Data Source
  KAKENHI-PROJECT-26350977
[Patent] 含窒素芳香族アミドの製造方法、ピロール・イミダゾールポリアミドの製造方法、及び化合物2016
- Inventor(s)
  根本哲宏、滋賀直樹、高柳志穂里、鈴木雄太、金田篤志
- Industrial Property Rights Holder
  根本哲宏、滋賀直樹、高柳志穂里、鈴木雄太、金田篤志
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-074677
- Filing Date
  2016-04-01
- Data Source
  KAKENHI-PROJECT-16K15608
[Patent] アシルニトロソ誘導体環化付加アントラセン誘導体及び光作動性HNO供与体2008
- Inventor(s)
  宮田直樹、中川秀彦、松尾和哉、鈴木孝禎
- Industrial Property Rights Holder
  名古屋市立大学
- Industrial Property Number
  2008-284899
- Filing Date
  2008-11-05
- Data Source
  KAKENHI-PROJECT-17590089
[Patent] ヒストン脱アセチル化酵素を阻害する新規化合物2005
- Inventor(s)
  宮田直樹, 鈴木孝禎, 松本徹也
- Industrial Property Rights Holder
  未定
- Industrial Property Number
  2006-058668
- Filing Date
  2005-03-03
- Data Source
  KAKENHI-PROJECT-17790092
[Presentation] エピジェネティックタンパク質複合体を標的とする創薬化学研究2024
- Author(s)
  鈴木孝禎
- Organizer
  星薬科大学学長主催セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] 独自の有機化学に基づくエピジェネティクス創薬2023
- Author(s)
  鈴木孝禎
- Organizer
  第72回構造生物応用研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18186
[Presentation] エピジェネティック阻害剤開発の現状と展望2023
- Author(s)
  鈴木　孝禎
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Identification of Epigenetic Protein-Protein Interaction Inhibitors2023
- Author(s)
  Takayoshi Suzuki
- Organizer
  AIMECS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18186
[Presentation] 創薬研究の最前線と量子ビームによる創薬の可能性2023
- Author(s)
  鈴木　孝禎
- Organizer
  JST 未来社会創造事業大規模プロジェクト型「レーザー駆動による量子ビーム加速器の開発と実証」－電子加速システムの開発－2022 年度第 2 回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Identification of Epigenetic Protein-Protein Interaction Inhibitors2023
- Author(s)
  Takayoshi Suzuki
- Organizer
  AIMECS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] エピジェネティクス複合体を標的とした創薬化学研究2023
- Author(s)
  鈴木孝禎
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] エピジェネティクス複合体を標的とする創薬化学研究2023
- Author(s)
  鈴木孝禎
- Organizer
  生体機能と創薬シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] 独自の有機化学に基づくエピジェネティクス創薬2023
- Author(s)
  鈴木孝禎
- Organizer
  第72回構造生物応用研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Discovery of epigenetic enzyme inhibitors by target-guided synthesis2022
- Author(s)
  Takayoshi Suzuki
- Organizer
  日本薬学会第１４２年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] エピジェネティクスを標的とする創薬・ケミカルバイオロジー研究2022
- Author(s)
  鈴木　孝禎
- Organizer
  第96回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] RNA創薬を志向した金属錯体型RNA分解分子の開発2022
- Author(s)
  花谷優太朗、黒原崇、山下泰信、高田悠里、伊藤幸裕、鈴木孝禎
- Organizer
  日本薬学会第１４２年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] 創薬 NF 検討会における人材育成活動と産学連携研究～解離遅延型阻害薬の新展開～2022
- Author(s)
  鈴木　孝禎
- Organizer
  第39回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Chemical Control of Epigenetics~Discovery of Histone Lysine Demethylase Inhibitors~2022
- Author(s)
  Takayoshi Suzuki
- Organizer
  Lecture in Global Frontiers in Life Science A, Kyoto University
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] ヒストン修飾を制御する化合物の探索2022
- Author(s)
  鈴木　孝禎
- Organizer
  第49回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] ヒストン修飾を制御する小分子化合物の探索2021
- Author(s)
  鈴木　孝禎
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] エピジェネティクスを標的とした創薬化学研究2021
- Author(s)
  鈴木　孝禎
- Organizer
  千里ライフサイエンス振興財団新適塾「未来創薬への誘い」第53回会合
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Induced-fit 型 HDAC 酵素阻害薬の同定とそのアロステリック作用の解析2021
- Author(s)
  伊藤幸裕、展鵬、東條敏史、鈴木美紀、李頴、内田周作、鈴木孝禎
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] 中枢神経性疾患治療を目指したエピジェネティクス制御化合物の創製2021
- Author(s)
  鈴木　孝禎
- Organizer
  第64回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] エピジェネティクス関連酵素に対する分解誘導薬の創製2021
- Author(s)
  伊藤幸裕、飯田哲也、Chotitumnavee Jiranan、高橋ゆかり、山下泰信、黒原崇、三宅由花、大庭誠、鈴木孝禎
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] 「エピジェネティクスを標的とした創薬化学研究」2021
- Author(s)
  鈴木孝禎
- Organizer
  立命館大学薬学部精密合成化学セミナー（第6回）
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Identification of lysine demethylase inhibitors as candidate therapeutic agents2021
- Author(s)
  Takayoshi Suzuki
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04795
[Presentation] Identification of Epigenetic Inhibitors by Target-Guided Synthesis2020
- Author(s)
  Takayoshi Suzuki
- Organizer
  Academia Sinica-Osaka University Symposium 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] Chemical control of epigenetics~Discovery of histone lysine demethylase inhibitors~2020
- Author(s)
  鈴木孝禎
- Organizer
  Lecture in Global Frontiers in Life Science A
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Identification of epigenetic inhibitors by target-guided synthesis2020
- Author(s)
  鈴木孝禎
- Organizer
  Academia Sinica-Osaka University Symposium 2020
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Chemical Control of Epigenetics for the Treatment of Cancers and Neurological Disorders2019
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 27th French-Japanese Symposium on Medicinal and Fine Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] Discovery of Epigenetic Inhibitors Using Target-Guided Synthesis2019
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 4th Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] Chemical Control of Epigenetics~Discovery of Histone Lysine Demethylase Inhibitors and Histone Deacetylase Inhibitors~2019
- Author(s)
  Takayoshi Suzuki
- Organizer
  Lecture in Global Frontiers in Life Science A, Kyoto University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] Chemical Control of Epigenetics for the Treatment of Diseases2018
- Author(s)
  Takayoshi Suzuki
- Organizer
  ICPAC Langkawi 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] A selective lysine-specific demethylase 1 inhibitor suppresses germ cell tumor proliferation2018
- Author(s)
  Etani Toshiki, Naiki Taku, Tanaka Yutaro, Iida Keitaro, Ando Ryosuke, Kawai Noriyasu, Tozawa Keiichi, Suzuki Takayoshi, Yasui Takahiro
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K20154
[Presentation] Targeting Histone Lysine Demethylases for Cancer Therapy2017
- Author(s)
  Takayoshi Suzuki
- Organizer
  2017 Queenstown Molecular Biology Meetings
- Place of Presentation
  Shanghai
- Year and Date
  2017-03-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Potent Mechanism-Based Sirtuin 2-Selective Inhibition by an in Situ Generated Occupant of Selectivity Pocket, Substrate-Binding Site, and NAD+-Bindig Pocket2017
- Author(s)
  Paolo MELLINI、伊藤幸裕、津元裕樹、李頴、鈴木美紀、徳田奈津子、柿澤多恵子、三浦ゆり、竹内淳、Maija LAHTELA-KAKKONEN、鈴木孝禎
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-14F04779
[Presentation] Region specific alteration of histone modification using LSD1 inhibitor conjugated with Pyrrole Imidazole Polyamide.2017
- Author(s)
  Kokiladevi Alagarswamy, Ken-ichi Shinohara, Atsushi Okabe, Masaki Fukuyo, Natsumi Yoda, Hiroki Nagase, Takayoshi Suzuki, Tetsuhiro Nemoto, Atsushi Kaneda.
- Organizer
  76th Annual Meeting of the Japanese Cancer Association,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15608
[Presentation] ヒストンアセチル化/メチル化を標的とした創薬研究2017
- Author(s)
  鈴木孝禎
- Organizer
  千葉大学再生システムと疾患・癌エピゲノム公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] A selective lysine-specific demethylase1 inhibitor suppresses germ cell tumor proliferation.2017
- Author(s)
  Etani Toshiki, Naiki Taku, Nagai Takashi, Iida Keitaro, Ando Ryosuke, Kawai Noriyasu, Takahashi Satoru, Suzuki Takayoshi, Yasui Takahiro
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K20154
[Presentation] Effectiveness of lysine specific demethylase 1 inhibitor for castration resistant prostate cancer.2017
- Author(s)
  Etani Toshiki, Naiki Taku, Nagai Takashi, Iida Keitaro, Ando Ryosuke, Kawai Noriyasu, Tozawa Keiichi, Mogami Tohru, Kohri Kenjiro, Suzuki Takayoshi, Yasui Takahiro
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K20154
[Presentation] Epigenetic driver of tumorigenesis in gastrointestinal cancer2017
- Author(s)
  Atsushi Kaneda, Keisuke Matsusaka, Eiji Sakai, Kenichi Shinohara, Natsumi Yoda, Hiroki Nagase, Tetsuhiro Nemoto, Kokiladevi Alagarswamy, Takayoshi Suzuki, Masaki Fukuyo, Atsushi Okabe, Kiyoko Takane, Sayaka Funata, Hiroe Namba
- Organizer
  International symposium for the drug-discovery of the pyrrole-imidazole polyamides as novel biomedicines
- Place of Presentation
  日本大学桜門会館（東京都・東京）
- Year and Date
  2017-02-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15608
[Presentation] エピジェネティクスを標的とした創薬研究2017
- Author(s)
  鈴木孝禎
- Organizer
  Kyoto University MIC/SK-Project Seminar
- Place of Presentation
  京都
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] エピジェネティクスを標的とした創薬研究2017
- Author(s)
  鈴木孝禎
- Organizer
  Kyoto University MIC/SK-Project Seminar
- Place of Presentation
  京都
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 新規SIRT2阻害剤による成人T細胞白血病細胞株の細胞死に対する検討2017
- Author(s)
  岡里佐子、小迫知弘、今石果奈、鈴木孝禎、Paolo Mellini、吉満誠、有馬直道、相川晃慶、本田伸一郎
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] エピジェネティクス制御に基づいた創薬研究2017
- Author(s)
  鈴木孝禎
- Organizer
  京都工芸繊維大学昆虫先端研究推進拠点シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] Novel selective lysine‐specific demethylase 1 inhibitors effectively impair castration‐resistant prostate cancer growth.2017
- Author(s)
  Etani Toshiki, Naiki Taku, Suzuki Takayoshi, Nagai Takashi, Iida Keitaro, Ando Ryosuke, Kawai Noriyasu, Tozawa Keiichi, Mogami Tohru, Yasui Takahiro
- Organizer
  American Urological Association Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20154
[Presentation] Discovery of isozyme-selective lysine demethylase inhibitors and deacetylase inhibitors2017
- Author(s)
  Takayoshi Suzuki
- Organizer
  AIMECS2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] エピジェネティクス制御に基づいた創薬研究～LSD1阻害薬の創製～2016
- Author(s)
  鈴木孝禎
- Organizer
  北海道大学生命科学特別講演会
- Place of Presentation
  札幌
- Year and Date
  2016-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 化学の力で難治性疾患に挑む～エピジェネティクス創薬化学～2016
- Author(s)
  鈴木孝禎
- Organizer
  第6回CSJ化学フェスタ2016
- Place of Presentation
  東京
- Year and Date
  2016-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Chemical Control of Epigenetics for Cancer Therapy ~Discovery of Histone Lysine Demethylase Inhibitors with Anticancer Activity~2016
- Author(s)
  Takayoshi Suzuki
- Organizer
  Chung-Ang University Center for Metareceptome Research 2016 International Symposium
- Place of Presentation
  Seoul
- Year and Date
  2016-10-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Discovery of Histone Lysine Demethylase Inhibitors with Anticancer Activity2016
- Author(s)
  Takayoshi Suzuki
- Organizer
  Eleventh Drug Discovery Chemistry~Epigenetic Inhibitor Discovery~
- Place of Presentation
  San Diego
- Year and Date
  2016-04-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Design, Synthesis and Biological evaluation of SNAIL1 Peptide-Based Lysine Specific Demethylase 1-Selective Inhibitors2016
- Author(s)
  Yukihiro Itoh, Keisuke Aihara, Paolo Mellini, Toshifumi Tojo, Yosuke Ota, Hiroki Tsumoto, Viswas Raja Solomon, Peng Zhan, Miki Suzuki, Daisuke Ogasawara, Akira Shigenaga, Tsubasa Inokuma, Hidehiko Nakagawa, Naoki Miyata, Tamio Mizukami, Akira Otaka, Takayoshi Suzuki
- Organizer
  The 53rd Japanese Peptide Syposium
- Place of Presentation
  京都
- Year and Date
  2016-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04779
[Presentation] 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway and SIRT2 Inhibitors Design: New Insight on Sirtuin Modulators2016
- Author(s)
  Paolo Mellini, Sergio Valente, Yukihiro Itoh, Taeko Kakizawa, Maija Lahtela-Kakkonen, Clemens Steegborn, Roberta Budriesi, Marco Tafani, Donatella Del Bufalo Lucia Altucci Carlo Gaetanoi, Antonello Mai, Takayoshi Suzuki
- Organizer
  International Symposium for RIKEN Epigenetics Program 2016
- Place of Presentation
  Wako
- Year and Date
  2016-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04779
[Presentation] エピジェネティクス制御因子阻害剤の創製とその応用2016
- Author(s)
  鈴木孝禎
- Organizer
  第３８回日本生物学的精神医学会・第５９回日本神経化学会大会合同年会脳とこころのエピジェネティクス創薬
- Place of Presentation
  福岡
- Year and Date
  2016-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Targeting Histone Demethylases for Cancer Therapy2016
- Author(s)
  Takayoshi Suzuki
- Organizer
  Kick-Off Symposium in Nagoya City University in 2016
- Place of Presentation
  Nagoya
- Year and Date
  2016-03-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 創薬を目指したエピジェネティクス制御の分子技術2016
- Author(s)
  鈴木孝禎
- Organizer
  日本化学会第９６春季年会分子設計と分子技術：その創りだす新しい世界
- Place of Presentation
  京田辺
- Year and Date
  2016-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Targeting Lysine Demethylases for Cancer Therapy2016
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 35th Sapporo International Cancer Symposium 2016~Cancer epigenome: from discovery to translation~
- Place of Presentation
  Sappaoro
- Year and Date
  2016-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 新規SIRT2阻害剤による白血病細胞株の細胞死に対する検討2016
- Author(s)
  今石果奈、小迫知弘、吉満誠、有馬直道、鈴木孝禎、大坪菜々子、相川晃慶、本田伸一郎、添田秦司
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Histone Lysine Demethylase Inhibitors for Cancer Therapy2016
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association ~Epigenetic therapeutic targets: Discovery and utilization~
- Place of Presentation
  Yokohama
- Year and Date
  2016-10-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 化学の力で難治性疾患に挑む～エピジェネティクス創薬化学～2016
- Author(s)
  鈴木孝禎
- Organizer
  第6回CSJ化学フェスタ2016
- Place of Presentation
  東京
- Year and Date
  2016-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] エピジェネティクス制御因子阻害剤の創製とその応用2016
- Author(s)
  鈴木孝禎
- Organizer
  第３８回日本生物学的精神医学会・第５９回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Year and Date
  2016-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0060
[Presentation] ヒドラジン構造を持つペプチド性LSD1阻害薬の創製2016
- Author(s)
  伊藤幸裕、粟飯原圭佑、Paolo Mellini、東條敏史、太田庸介、津元裕樹、Viswas Raja Solomon、Peng Zhan、鈴木美紀、小笠原大介、重永章、猪熊翼、中川秀彦、宮田直樹、水上民夫、大高章、鈴木孝禎
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-14F04779
[Presentation] ヒストン脱メチル化酵素を標的とした抗がん剤創製研究2016
- Author(s)
  鈴木孝禎
- Organizer
  千葉大学再生システムと疾患・癌エピゲノム公開シンポジウム
- Place of Presentation
  千葉
- Year and Date
  2016-09-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 創薬を目指したエピジェネティクス制御化合物の創製2015
- Author(s)
  鈴木孝禎
- Organizer
  天然物ケミカルバイオロジー地区シンポジウム
- Place of Presentation
  東北大学
- Year and Date
  2015-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-24689007
[Presentation] Toward SIRT7 inhibitors: From screening of known SIRT1-3 modulators to de novo-design2015
- Author(s)
  Paolo Mellini, Yukihiro Itoh, Taeko Kakizawa, Maija Lahtela-Kakkonen, Elina M. Jarho, Sergio Valente, Dante Rotili, Antonello Mai, Takayoshi Suzuki
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04779
[Presentation] 創薬を目指したエピジェネティクス制御化合物の創製2015
- Author(s)
  鈴木孝禎
- Organizer
  シオノギ未来創薬セミナー
- Place of Presentation
  札幌
- Year and Date
  2015-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] エピジェネティクス制御化合物の創製研究2015
- Author(s)
  鈴木孝禎
- Organizer
  近畿化学協会合成部会　平成２７年度　第１回合成フォーラム
- Place of Presentation
  神戸
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] エピジェネティクス制御化合物の創製と医薬への応用2015
- Author(s)
  鈴木孝禎
- Organizer
  第３１回若手化学者のための化学道場
- Place of Presentation
  淡路
- Year and Date
  2015-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] ポストゲノム時代の創薬研究～エピジェネティクス創薬～2015
- Author(s)
  鈴木孝禎
- Organizer
  日本薬学会東海支部特別講演会
- Place of Presentation
  岐阜
- Year and Date
  2015-05-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Discovery of histone lysine demethylase-selective inhibitors2015
- Author(s)
  Takayoshi Suzuki
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Chemical Control of Epigenetics ~Discovery of Histone Lysine Demethylase Inhibitors~2015
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 10th Asian Epigenomics Meeting 2015
- Place of Presentation
  Seoul
- Year and Date
  2015-09-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] 標的誘導型合成によるエピジェネティクス制御化合物の創製研究2015
- Author(s)
  鈴木孝禎
- Organizer
  第４９回分子認識科学を基盤とする創薬研究会
- Place of Presentation
  長崎
- Year and Date
  2015-06-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] Chemical Control of Epigenetics ~Discovery of Lysine Demethylase Inhibitors~2015
- Author(s)
  Takayoshi Suzuki
- Organizer
  The 40th Naito Conference
- Place of Presentation
  Sapporo
- Year and Date
  2015-09-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14982
[Presentation] SIRT1を標的とした成人T細胞白血病治療法に関する検討2014
- Author(s)
  小迫　知弘、馬島　礼、鈴木　孝禎、吉満　誠、相川　晃慶、本田　伸一郎、有馬　直道、添田　秦司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] エピジェネティクス制御化合物の開発2014
- Author(s)
  鈴木孝禎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-24689007
[Presentation] 新規SIRT1阻害剤による白血病細胞の細胞死に関する検討2014
- Author(s)
  内田　友一朗、小迫　知弘、鈴木　孝禎、馬島　礼、相川　晃慶、本田　伸一郎、吉満　誠⁾、有馬　直道、添田　秦司
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] エピジェネティクスのケミカルコントロール2014
- Author(s)
  鈴木孝禎
- Organizer
  第18回スクリプス・バイオメディカルフォーラム
- Place of Presentation
  大阪
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-24689007
[Presentation] 生物活性物質-タンパク質間におけるC-H…O水素結合の重要性2014
- Author(s)
  中島佑介、伊藤幸裕、鈴木孝禎
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本大学（熊本市）
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] 生物活性物質-タンパク質間におけるCH-O 水素結合の重要性2014
- Author(s)
  中島佑介, 伊藤幸裕, 鈴木孝禎
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] クリックケミストリーを用いたHDAC阻害薬の探索研究2013
- Author(s)
  後藤仰、鈴木孝禎, 他
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-24689007
[Presentation] Discovery of Histone Lysine Demethylase Inhibitors2013
- Author(s)
  Takayoshi Suzuki
- Organizer
  XXII National Meeting on Medicinal Chemistry (NMMC2013)
- Place of Presentation
  Rome
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] 新規SIRT1阻害剤による白血病細胞の増殖抑制効果に関する検討2013
- Author(s)
  馬島　礼、小迫　知弘、鈴木　孝禎、相川晃慶、本田　伸一郎、吉満　誠、有馬　直道、添田　秦司
- Organizer
  第6回HTLV-1研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] Identification of HDAC3-Selective Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly2013
- Author(s)
  Yosuke Ota, Takayoshi Suzuki et al
- Organizer
  2nd Annual Conference ICBS2013
- Place of Presentation
  京都大学（京都市）
- Data Source
  KAKENHI-PROJECT-24689007
[Presentation] Discovery of Histone Lysine Demethylase Inhibitors2013
- Author(s)
  Takayoshi Suzuki
- Organizer
  XXII National Meeting on Medicinal Chemistry (NMMC2013)
- Place of Presentation
  Sapienza University of Rome (Rome, Italy)
- Invited
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] エピジェネティクス機構を分子標的とする治療薬の進展2012
- Author(s)
  鈴木孝禎
- Organizer
  第25回インターフェックスジャパン / 第6回ファーマジャパン~医薬品原料国際展
- Place of Presentation
  東京ビッグサイト
- Year and Date
  2012-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] Discovery of isozyme-selective histone deacetylase inhibitors by click chemistry2012
- Author(s)
  Takayoshi Suzuki, Hidehiko Nakagawa, Naoki Miyata, et. al.
- Organizer
  ACS National Meetng, Sprong 2012
- Place of Presentation
  San Diego
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] ヒストン脱メチル化酵素JMJD2の阻害薬認識におけるCH-O水素結合の重要性2011
- Author(s)
  小笹弘貴, 鈴木孝禎, 浜田翔平, 三野光識, 中川秀彦, 水上民夫, 宮田直樹
- Organizer
  創薬懇話会2011
- Place of Presentation
  ダイヤモンド瀬戸内マリンホテル
- Year and Date
  2011-07-06
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] ヒストン脱メチル化酵素の阻害薬認識におけるCH-O水素結合の重要性2011
- Author(s)
  小笹弘貴, 鈴木孝禎, 浜田翔平, 三野光識, 中川秀彦, 水上民夫, 宮田直樹
- Organizer
  第57回日本薬学会東海支部総会・本会
- Place of Presentation
  金城学院大学
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] Design, Synthesis, and Biological Activity of cyclopropylamine-based LSD1 inhibitor2011
- Author(s)
  Daisuke Ogasawara, Takayoshi Suzuki, Hidehiko Nakagawa, Naoki Miyata, et. al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] HDAC8選択的阻害剤の創製とその応用2011
- Author(s)
  鈴木孝禎
- Organizer
  日本ケミカルバイオロジー学会第6年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] The Importance of CH-O Hydrogen Bonds in Protein-Ligand Binding2011
- Author(s)
  Hiroki Ozasa, Takayoshi Suzuki, Shohei Hamada, Koshiki Mino, Hidehiko Nakagawa, Tamio, Mizukami, Naoki Miyata
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] ヒストン脱メチル化酵素の阻害薬認識におけるCH-O水素結合の重要性2011
- Author(s)
  小笹弘貴，鈴木孝禎，浜田翔平，三野光識，中川秀彦，水上民夫，宮田直樹
- Organizer
  第５７回日本薬学会東海支部総会・本会
- Place of Presentation
  金城学院大学
- Data Source
  KAKENHI-PROJECT-23659012
[Presentation] Protein-Templated Copper-Catalyzed Azide-Alkyne Cycloaddition2011
- Author(s)
  Takayoshi Suzuki
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] Discovery of selective inhibitors of lysine specific demethylase-12010
- Author(s)
  T.Suzuki
- Organizer
  Pacifichem2010
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] Discovery of selective inhibitors of lysine specific demethylase-12010
- Author(s)
  T.Suzuki, 宮田直樹, et.al.
- Organizer
  Pacifichem2010
- Place of Presentation
  Honolulu, USA.
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] Discovery of selective inhibitors of lysine specific demethylase-12010
- Author(s)
  T. Suzuki, H. Nakagawa, N. Miyata, et. al.
- Organizer
  Pacifichem 2010
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] 触媒メカニズムを基に設計したボロン酸を有するHDAC阻害薬の創製2009
- Author(s)
  鈴木信明
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] HDAC6選択的阻害薬の創製とその応用2009
- Author(s)
  鈴木孝禎
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] 触媒メカニズムに基づいたSIRT阻害薬の創製2009
- Author(s)
  鈴木孝禎
- Organizer
  第7回次世代を担う有機化学シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] アイソフォーム選択的ヒストン脱アセチル化酵素阻害薬の創製研究2009
- Author(s)
  鈴木孝禎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] ボロン酸を有する新規HDAC阻害薬の設計、合成と活性評価2008
- Author(s)
  鈴木信明
- Organizer
  第54回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] ボロン酸を有する新規HDAC阻害薬の創製2008
- Author(s)
  鈴木信明
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-20390034
[Presentation] EPR Probes for Measuring Sub-cellular Oxidative Stress2007
- Author(s)
  Hidehiko Nakagawa, Shizuka Ban, Takayoshi Suzuki, Naoki M iyata
- Organizer
  the 4th Joint Meeting of the Society for Free Radical Research Australasia and Japan
- Place of Presentation
  Kyoto
- Year and Date
  2007-12-03
- Data Source
  KAKENHI-PROJECT-17590089
[Presentation] ニトロベンゼン構造に基づく新規光誘起型NOドナーの開発2006
- Author(s)
  中川秀彦, 鈴木孝禎, 加藤友香, 長江修, 福原潔, 宮田直樹
- Organizer
  日本ケミカルバイオロジー研究会第1回年会
- Place of Presentation
  東京
- Year and Date
  2006-05-08
- Data Source
  KAKENHI-PROJECT-17590089
[Presentation] エピジェネティクス機構を分子標的とする治療薬の進展
- Author(s)
  鈴木孝禎
- Organizer
  第25回インターフェックス　ジャパン／第6回ファーマジャパン～医薬品原料国際展
- Place of Presentation
  東京ビッグサイト（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23659012

1. MIYATA Naoki (50114674)

# of Collaborated Projects: 6 results

# of Collaborated Products: 24 results
2. NAKAGAWA Hidehiko (80281674)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
3. KOZAKO Tomohiro (40398300)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. Shinohara Ken-ichi (70378561)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KANEDA Atsushi (10313024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. NEMOTO Tetsuhiro (80361450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. Yamawaki Masanaga (30302855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 檀一平太 (20399380)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 鈴木健嗣 (30350474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 山下泰信 (10873408)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
11. 高田悠里 (20902357)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
12. 伊藤幸裕 (30636402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
13. PENG Zhan

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. MELLINI PAOLO

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
15. ZAMANI FARZAD

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TSUMOTO Hiroki (00409385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. KOHDA Kouhuku (60124286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Tamio Mizukami (80367896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. SASAKI Ryuzo (60077378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. HASEGAWA Makoto (10367899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. NAGAI Nobuo (90260281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Wada Shuichi (20378607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. Yoshida Minoru (80191617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Itoh Akihiro (40391859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. Kondo Yutaka (00419897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SHINJO Keiko (40641618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NATSUME Atsushi (30362255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. SUGIYAMA Hiroshi (50183843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. NAGASE Hiroki (90322073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. WATANABE Takayoshi (60526060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Iida Keitaro (30713945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
32. Yasui Takahiro (40326153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
33. Kawai Noriyasu (20254279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
34. Ando Ryosuke (30381867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
35. Naiki Taku (50551272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
36. Etani Toshiki (30600754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
37. YOSHIMITSU Makoto (70404530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
38. Sakai Toshiyuki (20186993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
39. 安田周祐 (10643398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 堀中真野 (80512037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
41. 戸原玄 (00396954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 赤石雄 (60532207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. YODA Natsumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. FUKUYO Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. TAKANE Kiyoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. FUJIWARA Kyoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. KITA Kazuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. FUKUDA Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. ZHAN Peng

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
50. SINGH RITESH

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. ELBORAY ELGHAREEB

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. YAMAGUCHI Junichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. MATSUSAKA Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. TATUM Prima

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
56. TATUM PrimaRoechelle

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 大谷隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 上野匡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 大杉剛生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 牟礼佳苗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 大矢進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 鈴木良明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 鬼頭宏彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. 稲津哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. 池田麻美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
67. 有馬直道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
68. 渡辺義文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 内田周作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
70. 山形弘隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
71. 内木綾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
72. 周大揚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
73. 朝野芳織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
74. 鈴木健之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
75. 山本英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
76. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
77. 加藤寛之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
78. 安藤朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
79. 白髭克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
80. 岡本祐幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Takayoshi 鈴木 孝禎

SUZUKI Takayoshi 鈴木 孝禎

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Development of chimera molecules targeting epigenetic complexesPrincipal Investigator

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Development of a new generation of antiviral agents that are effective against drug-resistant viruses and prevent serious illness and sequelae.Principal Investigator

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Development of innovative drug candidates by target guided synthesisPrincipal Investigator

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Medicinal chemistry targeting epigenetic long noncoding RNAsPrincipal Investigator

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Medicinal chemistry targeting epigenetic long noncoding RNAsPrincipal Investigator

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Design, synthesis and biological activity of SIRT7 inhibitorsPrincipal Investigator

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Development of inhibitors that stablize the transition state of enzymatic reactionsPrincipal Investigator

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ＣＨ活性化反応を利用したエピジェネティクス制御化合物の創製Principal Investigator

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Suzuki Takayoshi 鈴木孝禎

SUZUKI Takayoshi 鈴木孝禎