Shimamura Tatsuro 島村達郎

… Alternative Names

SHIMAMURA Tatsuro 島村達郎

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Researcher Number	90391979
Other IDs
Affiliation (Current)	2025: 昭和女子大学, 食健康科学部, 教授
Affiliation (based on the past Project Information) *help	2024: 昭和女子大学, 食健康科学部, 教授 2020 – 2023: 京都大学, 医学研究科, 特定准教授 2016 – 2021: 京都大学, 医学研究科, 特定講師 2017: 京都大学, 大学院医学研究科, 講師 2016 – 2017: 京都大学, 大学院医学研究科, 特定講師 … More 2011 – 2015: 京都大学, 医学(系)研究科(研究院), 講師 2012: 京都大学, 医学研究科, 講師 2012: 京都大学, 大学院・医学研究科, 特定講師 2011: 京都大学, 医学研究科, 特定講師 2010: 京都大学, 医学研究科, 客員研究員 2009: Kyoto University, 医学研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Molecular and Genome biology and related fields / Science and Engineering / Complex systems Except Principal Investigator Structural biochemistry / Applied microbiology
Keywords	Principal Investigator GPCR / 構造解析 / 受容体 / 結晶構造解析 / G蛋白質共役型受容体 / X線結晶構造解析 / シグナル伝達 / Gタンパク質共役型受容体 / 膜タンパク質 / トランスポーター … More / 輸送体 / X線結晶解析 / X線自由電子レーザー / XFEL / X線 / バイアス型 / 電子顕微鏡 / 癌 / 蛋白質 / タンパク質 / リガンド / 創薬 / 膜輸送体 / ヒスタミン / 花粉症 / アレルギー / 抗体 / アデノシン受容体 / Mhp1 / X線結晶構造解 / 交互アクセス機構 / 交互アクセスモデル / ヒダントイン … More Except Principal Investigator X線結晶構造解析 / ゲノム解析 / 非天然化合物 / コンフォメーション変化 / Ｘ線結晶構造解析 / 膜蛋白質 / コレステロール / トランスポーター / 胆汁酸 / 高脂血症 / 創薬ターゲット / 抗体 / 膜タンパク質 / ヒト膜蛋白質 / ヒト膜受容体 / ヒト膜タンパク質 Less

無脊椎動物のGPCRの構造解析とリガンド探索Principal Investigator
- Principal Investigator
  
  島村達郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Showa Women's University
Structural analysis of amine receptors for the development of new antipsychotic drugs.Principal Investigator
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
Challenges to the structural change analysis of G Protein-Coupled ReceptorsPrincipal Investigator
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
Biased GPCR signaling mechanismPrincipal Investigator
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
Structure determination of GPCRs using CryoEM.Principal Investigator
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Molecular and Genome biology and related fields
- Research Institution
  Kyoto University
Trial for determining the structure of CXCR7Principal Investigator
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodies
- Principal Investigator
  
  Nomura Norimichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Studies on the structure and function of a xenobiotic ABC transporter
- Principal Investigator
  
  YAJIMA SHUNSUKE
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo University of Agriculture
立体構造に基づくGPCRとリガンドの相互作用の解明Principal Investigator
- Principal Investigator
  
  島村達郎
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
X-ray crystallographic analyses of human serotonin receptors for structure-based drug discovery.
- Principal Investigator
  
  Kimura Kanako
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Structure determination of human membrane transportersPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
アロステリック抗体を用いたアデノシン受容体の構造解析Principal Investigator
- Principal Investigator
  
  島村達郎
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Structure determination of histamine H1 receptorPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Challenges for the structure determination of GPCR active conformationPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Elucidation of the transport mechanism of a secondary active transporter, Mhp1.Principal Investigator
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University

[Book] 構造生命科学による創薬への挑戦2022
- Author(s)
  岩崎憲治（編）、島村達郎ら
- Total Pages
  146
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21H02414
[Book] 構造生命科学による創薬への挑戦2022
- Author(s)
  岩崎憲治（編）、島村達郎ら
- Total Pages
  146
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20K21392
[Book] 構造生命科学による創薬への挑戦2022
- Author(s)
  岩崎憲治（編）、島村達郎ら
- Total Pages
  146
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-18H02388
[Book] 創薬研究のための相互作用解析パーフェクト2021
- Author(s)
  津本浩平・前仲勝実（編）、島村達郎ら
- Total Pages
  368
- Publisher
  羊土社
- ISBN
  9784758122566
- Data Source
  KAKENHI-PROJECT-18H02388
[Book] 創薬研究のための相互作用解析パーフェクト2021
- Author(s)
  津本浩平、前仲勝実、島村達郎ら
- Total Pages
  368
- Publisher
  羊土社
- ISBN
  9784758122566
- Data Source
  KAKENHI-PROJECT-20K21392
[Book] 創薬研究のための相互作用解析パーフェクト2021
- Author(s)
  津本浩平・前仲勝実（編）、島村達郎ら
- Total Pages
  368
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21H02414
[Book] Chapter 6 in Advanced Methods in Structural Biology2016
- Author(s)
  Shimamura T.
- Total Pages
  6
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26102725
[Journal Article] 尿管結石の形成を防ぐシュウ酸輸送体分子のX線結晶構造解析2024
- Author(s)
  島村　達郎
- Journal Title
  
  Isotope News
  
  Volume: 791 Pages: 11-13
- Data Source
  KAKENHI-PROJECT-21H02414
[Journal Article] Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota2023
- Author(s)
  Jaunet-Lahary Titouan、Shimamura Tatsuro、Hayashi Masahiro、Nomura Norimichi、Hirasawa Kouta、Shimizu Tetsuya、Yamashita Masao、Tsutsumi Naotaka、Suehiro Yuta、Kojima Keiichi、Sudo Yuki、Tamura Takashi、Iwanari Hiroko、Hamakubo Takao、Iwata So、Okazaki Kei-ichi、Hirai Teruhisa、Yamashita Atsuko
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1730-1730
- DOI
  10.1038/s41467-023-36883-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03195, KAKENHI-PROJECT-20K21392, KAKENHI-PROJECT-20K21482, KAKENHI-PROJECT-18H02388, KAKENHI-PUBLICLY-21H00404, KAKENHI-PROJECT-23K18239, KAKENHI-PROJECT-22K20632, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21H02414, KAKENHI-PROJECT-21H02446, KAKENHI-PROJECT-23K27415
[Journal Article] GPCRの構造解析研究2021
- Author(s)
  島村達郎
- Journal Title
  
  医学の歩み
  
  Volume: 278 Pages: 573-578
- Data Source
  KAKENHI-PROJECT-21H02414
[Journal Article] GPCRの構造解析研究2021
- Author(s)
  島村達郎
- Journal Title
  
  医学のあゆみ
  
  Volume: 278 Pages: 537-579
- Data Source
  KAKENHI-PROJECT-20K21392
[Journal Article] GPCRの構造解析研究2021
- Author(s)
  島村達郎
- Journal Title
  
  医学のあゆみ
  
  Volume: 278 Pages: 573-579
- Data Source
  KAKENHI-PROJECT-18H02388
[Journal Article] S1PR3?G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation2021
- Author(s)
  Toyomoto Masayasu、Inoue Asuka、Iida Kei、Denawa Masatsugu、Kii Isao、Ngako Kadji Francois Marie、Kishi Takayuki、Im Dohyun、Shimamura Tatsuro、Onogi Hiroshi、Yoshida Suguru、Iwata So、Aoki Junken、Hosoya Takamitsu、Hagiwara Masatoshi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 未定 Issue: 8 Pages: 1132-1144
- DOI
  10.1016/j.chembiol.2021.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-19H02856, KAKENHI-ORGANIZER-19H05776, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-20K21392, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-21H02414
[Journal Article] Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin2021
- Author(s)
  Oda Kazumasa、Nomura Takashi、Nakane Takanori、Yamashita Keitaro、Inoue Keiichi、Ito Shota、Vierock Johannes、Hirata Kunio、Maturana Andres D、Katayama Kota、( 32 authers )、Kandori Hideki、Hegemann Peter、Iwata So、Kubo Minoru、Nishizawa Tomohiro、Nureki Osamu
- Journal Title
  
  eLife
  
  Volume: 10 Pages: 1-21
- DOI
  10.7554/elife.62389
- NAID
  120006996980
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21251, KAKENHI-PROJECT-20K21383, KAKENHI-PROJECT-20K21392, KAKENHI-PROJECT-20K15754, KAKENHI-PUBLICLY-19H04959, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-20H05098, KAKENHI-PUBLICLY-20H05441, KAKENHI-PLANNED-20H05758, KAKENHI-PROJECT-18H03986, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-17H03007, KAKENHI-PROJECT-19H03195, KAKENHI-PROJECT-18J21256, KAKENHI-PROJECT-16H06294, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-20H03200, KAKENHI-PROJECT-21H02414
[Journal Article] The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone2020
- Author(s)
  Asada Hidetsugu、Inoue Asuka、Ngako Kadji Francois Marie、Hirata Kunio、Shiimura Yuki、Im Dohyun、Shimamura Tatsuro、Nomura Norimichi、Iwanari Hiroko、Hamakubo Takao、Kusano-Arai Osamu、Hisano Hiromi、Uemura Tomoko、Suno Chiyo、Aoki Junken、Iwata So
- Journal Title
  
  Structure
  
  Volume: 28 Issue: 4 Pages: 418-425.e4
- DOI
  10.1016/j.str.2019.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K16217, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone2020
- Author(s)
  Im Dohyun、Inoue Asuka、Fujiwara Takaaki、Nakane Takanori、Yamanaka Yasuaki、Uemura Tomoko、Mori Chihiro、Shiimura Yuki、Kimura Kanako Terakado、Asada Hidetsugu、Nomura Norimichi、Tanaka Tomoyuki、Yamashita Ayumi、Nango Eriko、Tono Kensuke、Kadji Francois Marie Ngako、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-020-20221-0
- NAID
  120006943309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02394, KAKENHI-PROJECT-18K05334, KAKENHI-ORGANIZER-19H05776, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine2019
- Author(s)
  Kimura Kanako Terakado、Asada Hidetsugu、Inoue Asuka、Kadji Francois Marie Ngako、Im Dohyun、Mori Chihiro、Arakawa Takatoshi、Hirata Kunio、Nomura Yayoi、Nomura Norimichi、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 26 Issue: 2 Pages: 121-128
- DOI
  10.1038/s41594-018-0180-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure2019
- Author(s)
  Shimazu Yoshiaki、Tono Kensuke、Tanaka Tomoyuki、Yamanaka Yasuaki、Nakane Takanori、Mori Chihiro、Terakado Kimura Kanako、Fujiwara Takaaki、Sugahara Michihiro、Tanaka Rie、Doak R. Bruce、Shimamura Tatsuro、Iwata So、Nango Eriko、Yabashi Makina
- Journal Title
  
  Journal of Applied Crystallography
  
  Volume: 52 Issue: 6 Pages: 1280-1288
- DOI
  10.1107/s1600576719012846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02394, KAKENHI-PROJECT-17K19349, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] Structural basis for the substrate recognition of aminoglycoside 7′′-phosphotransferase-Ia from Streptomyces hygroscopicus2019
- Author(s)
  Takenoya Mihoko、Shimamura Tatsuro、Yamanaka Ryuji、Adachi Yuya、Ito Shinsaku、Sasaki Yasuyuki、Nakamura Akira、Yajima Shunsuke
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 75 Issue: 9 Pages: 599-607
- DOI
  10.1107/s2053230x19011105
- NAID
  120007133009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388
[Journal Article] 5-HT2A受容体の構造から解明された薬剤の受容体選択機構2019
- Author(s)
  島村達郎
- Journal Title
  
  医学のあゆみ
  
  Volume: 270 Pages: 1152-1153
- Data Source
  KAKENHI-PROJECT-17K19349
[Journal Article] Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA2018
- Author(s)
  Suno Ryoji、Kimura Kanako Terakado、Nakane Takanori、Fujiwara Takaaki、Yamanaka Yasuaki、Im Dohyun、Rosenbaum Daniel M.、Iwata So、Shimamura Tatsuro、Kobayashi Takuya
- Journal Title
  
  Structure
  
  Volume: 26 Issue: 1 Pages: 7-19
- DOI
  10.1016/j.str.2017.11.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15K08268, KAKENHI-PROJECT-15K18376
[Journal Article] Structure, Substrate Recognition, and Mechanism of the Na+-Hydantoin Membrane Transport Protein, Mhp12018
- Author(s)
  Jackson Scott M.、Ivanova Ekaterina、Calabrese Antonio N.、Polyakova Anna、Sharples David J.、Shimamura Tatsuro、Cameron Alexander D.、Henderson Peter J. F., et al.
- Journal Title
  
  Encyclopedia of Biophysics
  
  Volume: 1 Pages: 1-12
- DOI
  10.1007/978-3-642-35943-9_10091-1
- ISBN
  9783642359439
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388
[Journal Article] Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog2018
- Author(s)
  Asada H, Horita S, Hirata K, Shiroishi M, Shiimura Y, Iwanari H, Hamakubo T, Shimamura T, Nomura N, Kusano-Arai O, Uemura T, Suno C, Kobayashi T, Iwata S.
- Journal Title
  
  Nature Structural and Molecular Biology
  
  Volume: 25 Issue: 7 Pages: 570-576
- DOI
  10.1038/s41594-018-0079-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388
[Journal Article] A three dimensional movie of structural changes in bacteriorhodopsin.2016
- Author(s)
  Nango, E., Royant, A.†, Kubo, M.† et al. (†equal contribution)(45名中2番目)
- Journal Title
  
  Science
  
  Volume: 354 Issue: 6319 Pages: 1552-1557
- DOI
  10.1126/science.aah3497
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01055, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18486, KAKENHI-PROJECT-15K18523, KAKENHI-PROJECT-16H06315
[Journal Article] Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.2016
- Author(s)
  Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 11030-11030
- DOI
  10.1038/ncomms11030
- NAID
  130007529314
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-16H06145
[Journal Article] Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent2016
- Author(s)
  Takanori Nakane, Shinya Hanashima, Mamoru Suzuki, Haruka Saiki, Taichi Hayashi, Keisuke Kakinouchi, Shigeru Sugiyama, Satoshi Kawatake, Shigeru Matsuoka, Nobuaki Matsumori, et al
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 113 Issue: 46 Pages: 13039-13044
- DOI
  10.1073/pnas.1602531113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-26840021, KAKENHI-PROJECT-15K18487
[Journal Article] High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1.2016
- Author(s)
  Horita S, Nomura Y, Sato Y, Shimamura T, Iwata S, Nomura N.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 35297-35297
- DOI
  10.1038/srep35297
- NAID
  120005850219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15J04343, KAKENHI-PROJECT-15K06968
[Journal Article] Overview of Membrane Protein Purification and Crystallization2016
- Author(s)
  Shimamura T.
- Journal Title
  
  Advanced Methods in Structural Biology
  
  Volume: なし
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04338
[Journal Article] Structure and mechanism of the mammalian fructose transporter GLUT52015
- Author(s)
  Nomura N, Verdon G, Kang HJ, Shimamura T, Nomura Y, Sonoda Y, Hussien SA, Qureshi AA, Coincon M, Sato Y, Abe H, Nakada-Nakura Y, Hino T, Arakawa T, Kusano-Arai O, Iwanari H, Murata T, Kobayashi T, Hamakubo T, Kasahara M, Iwata S, Drew D
- Journal Title
  
  Nature
  
  Volume: 526 Issue: 7573 Pages: 397-401
- DOI
  10.1038/nature14909
- NAID
  120005657713
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PLANNED-24108007, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25711004
[Journal Article] Grease matrix as a versatile carrier of proteins for serial crystallography.2015
- Author(s)
  Sugahara M, Shimamura T, et al.
- Journal Title
  
  Nat Methods.
  
  Volume: 12 Issue: 1 Pages: 61-63
- DOI
  10.1038/nmeth.3172
- NAID
  120005682565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-25450167, KAKENHI-PROJECT-25650023, KAKENHI-PROJECT-25650051, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-26560448
[Journal Article] Diverse application platform for hard X-ray diffraction in SACLA (DAPHNIS): application to serial protein crystallography using an X-ray free-electron laser.2015
- Author(s)
  Tono K, Shimamura T, et al.
- Journal Title
  
  J. Synchrotron Rad.
  
  Volume: 22 Issue: 3 Pages: 532-537
- DOI
  10.1107/s1600577515004464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-25650023, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15H04338
[Journal Article] Native sulfur/chlorine SAD phasing for serial femtosecond crystallography.2015
- Author(s)
  Nakane T, Song C, Suzuki M, Nango E, Kobayashi J, Masuda T, Inoue S, Mizohata E, Nakatsu T, Tanaka T, Tanaka R, Shimamura T, Tono K, Joti Y, Kameshima T, Hatsui T, Yabashi M, Nureki O, Iwata S, Sugahara M.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr.
  
  Volume: 71 Issue: 12 Pages: 2519-25
- DOI
  10.1107/s139900471501857x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440028, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25450167, KAKENHI-PROJECT-15K14941, KAKENHI-PROJECT-25650026
[Journal Article] X-ray structure of histamine H1 receptor2014
- Author(s)
  Shimamura T.
- Journal Title
  
  Nihon Yakurigaku Zasshi.
  
  Volume: 144 Pages: 43-4
- NAID
  130004437205
- Data Source
  KAKENHI-PROJECT-25650023
[Journal Article] Crystal structure of a symmetric football-shaped GroEL:GroES2-ATP14 complex determined at 3.8Å reveals rearrangement between two GroEL rings.2014
- Author(s)
  Koike-Takeshita A, Arakawa T, Taguchi H, Shimamura T.
- Journal Title
  
  J Mol Biol.
  
  Volume: 426 Issue: 21 Pages: 3634-41
- DOI
  10.1016/j.jmb.2014.08.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-25440055, KAKENHI-PROJECT-25650023, KAKENHI-PUBLICLY-26102725, KAKENHI-ORGANIZER-26116001, KAKENHI-PLANNED-26116002
[Journal Article] ヒスタミンH1受容体2014
- Author(s)
  島村達郎
- Journal Title
  
  日本薬理学会誌
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650023
[Journal Article] Proteoliposome-based selection of a recombinant antibody fragment against the human M2 muscarinic acetylcholine receptor.2014
- Author(s)
  Suharni, Nomura Y, Arakawa T, Hino T, Abe H, Nakada-Nakura Y, Sato Y, Iwanari H, Shiroishi M, Asada H, Shimamura T, Murata T, Kobayashi T, Hamakubo T, Iwata S, Nomura N.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 33 Issue: 6 Pages: 378-385
- DOI
  10.1089/mab.2014.0041
- NAID
  120005530933
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25650023, KAKENHI-PROJECT-25709080, KAKENHI-PUBLICLY-26102725
[Journal Article] ヒスタミンH1受容体の構造2014
- Author(s)
  島村達郎
- Journal Title
  
  日本薬理学会誌
  
  Volume: 未定
- NAID
  130004437205
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24121715
[Journal Article] X-ray structure of histamine H1 receptor2014
- Author(s)
  Shimamura T.
- Journal Title
  
  Nihon Yakurigaku Zasshi.
  
  Volume: 144 Pages: 43-4
- NAID
  130004437205
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] ヒスタミンH１受容体の構造2014
- Author(s)
  島村達郎
- Journal Title
  
  日本薬理学会誌
  
  Volume: 未定
- NAID
  130004437205
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] ヒスタミン受容体2013
- Author(s)
  島村達郎
- Journal Title
  
  膜タンパク質構造研究
  
  Volume: １ Pages: 11-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] ヒスタミン受容体2013
- Author(s)
  島村達郎
- Journal Title
  
  膜タンパク質構造研究
  
  Volume: １ Pages: 11-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650023
[Journal Article] ヒスタミン受容体2013
- Author(s)
  島村達郎
- Journal Title
  
  膜タンパク質構造研究
  
  Volume: 1 Pages: 11-18
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24121715
[Journal Article] Structural biology and molecular targets.2012
- Author(s)
  Shimamura T
- Journal Title
  
  Nihon Rinsho.
  
  Volume: 70 Pages: 316-20
- Data Source
  KAKENHI-PUBLICLY-24121715
[Journal Article] Structural biology and molecular targets2012
- Author(s)
  Shimamura T, Iwata S.
- Journal Title
  
  Nihon Rinsho
  
  Volume: Nov;70 Suppl 8 Pages: 316-20
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharoroyces cerevisiae.2012
- Author(s)
  Shiroishi M., et al.
- Journal Title
  
  Micorb, Cell Fact.
  
  Volume: 11 Issue: 1 Pages: 78-78
- DOI
  10.1186/1475-2859-11-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074, KAKENHI-PROJECT-23770123, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PUBLICLY-24121715
[Journal Article] Structural biology and molecular targets.2012
- Author(s)
  Shimamura T.
- Journal Title
  
  Nihon Rinsho.
  
  Volume: 70 Pages: 316-20
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] Structure of histamine H1 receptor2012
- Author(s)
  Shimamura T
- Journal Title
  
  Seikagaku.
  
  Volume: 84(9) Pages: 772-6
- NAID
  10031122382
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] 創薬ターゲット膜蛋白質の立体構造解析2012
- Author(s)
  島村達郎
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 35 Pages: 557-564
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] Structural biology and molecular targets.2012
- Author(s)
  Shimamura T., Iwata S.
- Journal Title
  
  Nihon Rinsho.
  
  Volume: 70 Pages: 316-320
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] Structure of histamine H1 receptor.2012
- Author(s)
  Shimamura T.
- Journal Title
  
  Seikagaku.
  
  Volume: 84 Pages: 772-6
- NAID
  10031122382
- Data Source
  KAKENHI-PUBLICLY-24121715
[Journal Article] G protein-coupled receptor inactivation by an allosteric inverse-agonist antibody2012
- Author(s)
  Hino T., et al
- Journal Title
  
  Nature
  
  Volume: 482 Issue: 7384 Pages: 237-40
- DOI
  10.1038/nature10750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074
[Journal Article] The Na+-hydantoin membrane transport protein2012
- Author(s)
  Jackson SM, Ivanova E, Simmons K, Patching SG, Weyand S, Shimamura T, Brueckner F, Iwata S, Sharples DJ, Baldwin SA, Sansom MPS, Beckstein O, Cameron AD, Henderson PJF
- Journal Title
  
  Encyclopedia of Biophysics Springer
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Structure of histamine H1 receptor.2012
- Author(s)
  Shimamura T.
- Journal Title
  
  Seikagaku.
  
  Volume: 84 Pages: 772-6
- NAID
  10031122382
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] 創薬ターゲット膜蛋白質の立体構造解析2012
- Author(s)
  島村達郎、小笠原諭、岩田想
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 35 Pages: 557-564
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] Structure of histamine H1 receptor.2012
- Author(s)
  Shimamura T.
- Journal Title
  
  Seikagaku.
  
  Volume: 84 Pages: 772-776
- NAID
  10031122382
- Data Source
  KAKENHI-PROJECT-24370044
[Journal Article] The Na+-hydantoin membrane transport protein, Mhp12012
- Author(s)
  Weyand S.Shimamura T., et al
- Journal Title
  
  Encyclopedia of Biophysics
  
  Volume: (掲載確定)
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Conformational transition of the lid helix covering the proteaseactive site is essential for the ATP-dependent protease activity of FtsH.2012
- Author(s)
  Suno R, Shimoyama M, Abe A, Shimamura T, Shimodate N, Watanabe YH, Akiyama Y, Yoshida M.
- Journal Title
  
  FEBS Lett
  
  Volume: 586(19) Pages: 3117-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] 創薬ターゲット膜蛋白質の立体構造解析2012
- Author(s)
  島村達郎
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 35 Pages: 557-564
- Data Source
  KAKENHI-PUBLICLY-24121715
[Journal Article] The Alternating Access Mechanism of Transport as Observed in the Sodium-Hydantoin Transporter Mhp12011
- Author(s)
  Weyand S, Shimamura T, Beckstein O, Sansom M, Iwata S, Henderson P, Cameron A.
- Journal Title
  
  J. Synchrotron Rad.
  
  Volume: 18 Issue: 1 Pages: 20-23
- DOI
  10.1107/s0909049510032449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] The Nucleobase-Cation-Symport-1 family of Membrane Transport Proteins2011
- Author(s)
  Weyand S, Ma P, Beckstein O, Baldwin J, Jackson S, Suzuki S, Shimamura T, Sansom M, Iwata S, Cameron A, Baldwin S, Henderosn P.
- Journal Title
  
  John Wiley and Sons, Ltd
  
  Pages: 004-009
- DOI
  10.1002/0470028637.met268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor.2011
- Author(s)
  de Graaf C, Kooistra AJ, Vischer HF, Katritch V, Kuijer M, Shiroishi M, Iwata S, Shimamura T, Stevens RC, de Esch IJ, Leurs R.
- Journal Title
  
  J Med Chem.
  
  Volume: 54(23) Issue: 23 Pages: 8195-206
- DOI
  10.1021/jm2011589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi M, Kobayashi T, Shimamura T., et al
- Journal Title
  
  Methods
  
  Volume: 55 Issue: 4 Pages: 281-286
- DOI
  10.1016/j.ymeth.2011.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-23657074
[Journal Article] ヒダントイン輸送体に見る膜輸送機構の構造基盤2011
- Author(s)
  島村達郎
- Journal Title
  
  生物物理
  
  Volume: 51 Pages: 4-9
- NAID
  10027414674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi M, Kobayashi T, Ogasawara S, Tsujimoto H, Ikeda-Suno C, Iwata S, Shimamura T.
- Journal Title
  
  Methods.
  
  Volume: 55(4) Pages: 281-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Structure ofthe human histamine H1 receptor complexwith doxepin.2011
- Author(s)
  Shimamura, T., Shiroishi, M, Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Han, G. W., Kobayashi, T., Stevens, R. C. and Iwata, S
- Journal Title
  
  Nature
  
  Volume: 475 Issue: 7354 Pages: 65-70
- DOI
  10.1038/nature10236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23657074
[Journal Article] Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T., Iwata, S., Kobayashi, T
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 10 Issue: 1 Pages: 24-24
- DOI
  10.1186/1475-2859-10-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04341, KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium2011
- Author(s)
  Tokuda N, Igarashi K, Shimamura T(co-1st author), Yurugi-Kobayashi T, Shiroishi M, Ito K, Sugawara T, Asada H, Murata T, Nomura N, Iwata S, Kobayashi T.
- Journal Title
  
  Protein. Expr. Purif.
  
  Volume: 79(1) Issue: 1 Pages: 81-7
- DOI
  10.1016/j.pep.2011.04.006
- NAID
  120003255719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23657074
[Journal Article] The Nucleobase-Cation-Symport-1 family of Membrane Transport Proteins2011
- Author(s)
  Weyand S.Shimamura T., et al
- Journal Title
  
  Handbook of Metalloproteins
  
  Volume: 4 and 5 Pages: 848-864
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Crystal Structure of Glucansucrase from the Dental Caries Pathogen Streptococcus mutans2011
- Author(s)
  Ito K, Ito S, Shimamura T(co-1st author), Weyand S, Kawarasaki Y, Misaka T, Abe K, Kobayashi T, Cameron AD, Iwata S.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 408(2) Issue: 2 Pages: 177-86
- DOI
  10.1016/j.jmb.2011.02.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-21760645, KAKENHI-PROJECT-23248058, KAKENHI-PROJECT-23780139
[Journal Article] ヒスタミンH1受容体の立体構造解明と創薬への期待2011
- Author(s)
  島村達郎、岩田想
- Journal Title
  
  日本医事新報
  
  Volume: 4564 Pages: 50-51
- Data Source
  KAKENHI-PROJECT-23657074
[Journal Article] Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans2010
- Author(s)
  Ito K, Ito S, Shimamura T, Kawarasaki Y, Abe K, Misaka T, Kobayashi T, Iwata S.
- Journal Title
  
  Acta Crystallogr
  
  Volume: 66 Issue: 9 Pages: 1086-1088
- DOI
  10.1107/s1744309110029714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter, Mhp12010
- Author(s)
  Shimamura T, et al.
- Journal Title
  
  Science (印刷中)
- NAID
  10027414674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] 立体構造より明らかとなったヒダントイン輸送体Mhp 1の輸送機構2010
- Author(s)
  島村達郎
- Journal Title
  
  実験医学28
  
  Volume: 28 Pages: 2639-2642
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp12010
- Author(s)
  Shimamura T, Weyand S, Beckstein O, Rutherford NG, Hadden JM, Sharples D, Sansom MSP, Iwata S, Henderson PJ, Cameron AD.
- Journal Title
  
  Science(Article)
  
  Volume: 328 Issue: 5977 Pages: 470-473
- DOI
  10.1126/science.1186303
- NAID
  10027414674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp12010
- Author(s)
  島村達郎, CameronAD, 岩田想
- Journal Title
  
  実験医学
  
  Volume: 28 Pages: 2639-2642
- NAID
  10027414674
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter, Mhp12010
- Author(s)
  Shimamura T, et al.
- Journal Title
  
  Science
  
  Volume: 328 Pages: 470-473
- NAID
  10027414674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Patent] アゴニストの親和性を亢進する抗ヒトアデノシンA2a受容体モノクローナル抗体2012
- Inventor(s)
  小笠原諭日野智也島村達郎荒川孝俊万木貴美寿野千代村田武士小林拓也岩田想
- Industrial Property Number
  2012-049812
- Filing Date
  2012-03-06
- Data Source
  KAKENHI-PROJECT-23657074
[Patent] アゴニストの親和性を亢進する抗ヒトアデノシンA2a受容体モノクローナル抗体2012
- Inventor(s)
  小笠原諭, 島村達郎ら
- Industrial Property Rights Holder
  （独）科学技術振興機構
- Industrial Property Number
  2012-049812
- Filing Date
  2012
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structural insights into antipsychotics binding modes in dopamine D2-class receptors2018
- Author(s)
  Dohyun Im, Tatsuro Shimamura, et al.
- Organizer
  Keystone Symposia: GPCR Structure and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19349
[Presentation] Structure of orexin receptor determined using X-ray free electron laser.2018
- Author(s)
  Shimamura T.
- Organizer
  AsCA 2018/Crystal32
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19349
[Presentation] Structure of orexin receptor determined using X-ray free electron laser.2018
- Author(s)
  Shimamura T.
- Organizer
  AsCA 2018/Crystal32
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02388
[Presentation] Microbacterium hydrocarbonoxydans由来ABCトランスポーター基質結合サブユニットの結晶構造解析2018
- Author(s)
  島村香穂、秋山友了、竹野谷美穂子、伊藤晋作、佐々木康幸、高谷直樹、矢嶋俊介
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-15K07369
[Presentation] A first novel GPCR structure determined at SACLA2017
- Author(s)
  Dohyun Im, Tatsuro Shimamura, So Iwata
- Organizer
  The International Symposium on Frontiers in structural biology for drug development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04338
[Presentation] A first novel GPCR structure determined at SACLA2017
- Author(s)
  Dohyun Im, Tatsuro Shimamura, So Iwata
- Organizer
  International Symposium on Frontiers in structural biology for Drug Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19349
[Presentation] X線自由電子レーザーを利用したGPCRのシリアルフェムト秒結晶構造解析2017
- Author(s)
  島村達郎
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H04338
[Presentation] X線自由電子レーザーを用いたGPCRの構造解析2016
- Author(s)
  島村達郎
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  博多
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-15H04338
[Presentation] ヒスタミンH1受容体による抗ヒスタミン薬の認識機構2016
- Author(s)
  藤原孝彰，森本志保，山中保明，中根崇智，平田邦生，山下恵太郎，岩田想，島村達郎
- Organizer
  日本結晶学会2016年度年会
- Place of Presentation
  水戸
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15H04338
[Presentation] 膜蛋白質のSFXによる迅速位相決定を志向したヨウ素含有界面活性剤の開発2016
- Author(s)
  中根智、花島慎弥、鈴木守、斎木悠、林太一、垣之内啓介、杉山成、川竹悟史、松岡茂、松森信明、南後恵理子、小林淳、島村達郎、木村香菜子、森千寿、国島直樹、菅原道泰、高久陽子、井上茂之、桝田哲哉、保坂俊彰、登野健介、城地保昌、亀島敬、初井宇記、矢橋牧名、井上豪、濡木理、岩田想、村田道雄、溝端栄一
- Organizer
  日本結晶学会平成28年度年会
- Place of Presentation
  茨城　水戸
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-26840021
[Presentation] X線自由電子レーザーを用いたGPCRの構造解析2016
- Author(s)
  島村達郎
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  博多
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102725
[Presentation] X線自由電子レーザーを用いたGPCRの構造解析2016
- Author(s)
  島村達郎
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-15H04338
[Presentation] ヒスタミンH1 受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  第８７回日本内分泌学会学術総会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] ヒスタミンH1受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  日本内分泌学会学術総会
- Place of Presentation
  博多
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-25650023
[Presentation] ヒスタミンH１受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  第８７回日本内分泌学会
- Place of Presentation
  博多
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] ヒスタミンH1受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  第８７回日本内分泌学会学術総会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-25650023
[Presentation] ヒスタミンH1受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  日本内分泌学会学術総会
- Place of Presentation
  博多
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] ヒスタミンH1受容体の構造解析とin silico screening2014
- Author(s)
  島村達郎
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  博多
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102725
[Presentation] Crystal structure of Histamine H1 receptor and drug design.2013
- Author(s)
  Shimamura T
- Organizer
  The 11th International Symposium for Future Drug Discovery and Medical Care.
- Place of Presentation
  Sapporo
- Invited
- Data Source
  KAKENHI-PROJECT-25650023
[Presentation] Crystal structure of Histamine H1 receptor and drug design.2013
- Author(s)
  Shimamura T.
- Organizer
  The 11th International Symposium for Future Drug Discovery and Medical Care.
- Place of Presentation
  Sapporo
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] Crystal structure of Histamine H1 receptor and drug design.2013
- Author(s)
  Shimamura T
- Organizer
  The 11th International Symposium for Future Drug Discovery and Medical Care.
- Place of Presentation
  Sapporo
- Invited
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] ヒスタミンH１受容体の構造により解明された抗ヒスタミン薬選択性機構2012
- Author(s)
  島村達郎
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-11-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] Structural studies of human G-protein coupled receptors2012
- Author(s)
  Shimamura T.
- Organizer
  日本農芸化学会2012 年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] ヒト由来ヒスタミンH１受容体の立体構造2012
- Author(s)
  島村達郎
- Organizer
  第９回　GPCR研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] キュービックフェーズ法による膜タンパク質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  蛋白研セミナー
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] Structural studies of human G-protein coupled receptors.2012
- Author(s)
  Shimamura T.
- Organizer
  日本農芸化学会2012年度大会(招待講演)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 微結晶を用いた創薬ターゲット膜タンパク質の構造解析とSACLAの可能性2012
- Author(s)
  島村達郎
- Organizer
  第25回日本放射光学会年会放射光科学合同シンポジウム(招待講演)
- Place of Presentation
  鳥栖
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structural studies of human G-protein coupled receptors2012
- Author(s)
  Shimamura T.
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都府)(招待講演)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] 微結晶を用いた創薬ターゲット膜タンパク質の構造解析とSACLAの可能性2012
- Author(s)
  島村達郎
- Organizer
  第25回日本放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  鳥栖市民文化会館(佐賀県)
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒト由来ヒスタミンH1受容体の立体構造2012
- Author(s)
  島村達郎
- Organizer
  第9回 GPCR研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-11
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structural studies of human G-protein coupled receptors2012
- Author(s)
  Shimamura T.
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都府)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒト由来ヒスタミンH1受容体の立体構造2012
- Author(s)
  島村達郎
- Organizer
  第9回 GPCR研究会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2012-05-11
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] キュービックフェーズ法による膜タンパク質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  蛋白研セミナー
- Place of Presentation
  大阪
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回　日本蛋白質科学会(招待講演)
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 微結晶を用いた創薬ターゲット膜タンパク質の構造解析とSACLAの可能性2012
- Author(s)
  島村達郎
- Organizer
  第25回日本放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  鳥栖市民文化会館(佐賀県)(招待講演)
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒスタミンH1受容体の構造により解明された抗ヒスタミン薬選択性機構2012
- Author(s)
  島村達郎
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] キュービックフェーズ法による膜タンパク質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  蛋白研セミナー
- Place of Presentation
  大阪
- Year and Date
  2012-09-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] ヒスタミンH1受容体の構造により解明された抗ヒスタミン薬選択性機構2012
- Author(s)
  島村達郎
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24370044
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)(発表確定)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 微結晶を用いた創薬ターゲット膜タンパク質の構造解析とSACLAの可能性2012
- Author(s)
  島村達郎
- Organizer
  第25回日本放射光学会年会放射光科学合同シンポジウム
- Place of Presentation
  鳥栖
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 膜蛋白質の結晶化2012
- Author(s)
  島村達郎
- Organizer
  第12回　日本蛋白質科学会
- Place of Presentation
  名古屋
- Year and Date
  2012-06-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121715
[Presentation] ヒト由来ヒスタミン受容体H1の構造解析戦略2011
- Author(s)
  島村達郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Structural basis of secondary active transport in the sodium-hydantoin transporter Mhp12011
- Author(s)
  Shimamura T.
- Organizer
  The JSPS/iCeMS International Symposium
- Place of Presentation
  京都大学(京都府)(招待講演)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒト由来ヒスタミン受容体H1 の構造解析戦略2011
- Author(s)
  島村達郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structural basis of secondary active transport in the sodium-hydantoin transporter Mhp12011
- Author(s)
  Shimamura T.
- Organizer
  The JSPS/iCeMS International Symposium.
- Place of Presentation
  京都大学(京都府)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒスタミンH1 受容体の立体構造から分かった抗ヒスタミン薬選択性の分子機構2011
- Author(s)
  島村達郎
- Organizer
  第18回創薬情報研究会
- Place of Presentation
  大阪
- Year and Date
  2011-12-22
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structure of the human histamine H1 receptor with doxepin.2011
- Author(s)
  Shimamura T. et al.
- Organizer
  International Union of Crystallography, XXII Congress and General Assembly.(招待講演)
- Place of Presentation
  マドリッド（スペイン）
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] ヒト由来ヒスタミン受容体H1の構造解析戦略2011
- Author(s)
  島村達郎, ら
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Structure of the human histamine H1 receptor with doxepin2011
- Author(s)
  Shimamura T., et al.
- Organizer
  International Union of Crystallography, XXII Congress and General Assembly
- Place of Presentation
  Madrid(Spain)
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒダントイン輸送体Mhp1の基質輸送中の動き2011
- Author(s)
  島村達郎
- Organizer
  生理研研究会
- Place of Presentation
  岡崎コンファレンスセンター(愛知県)(招待講演)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒト由来ヒスタミン受容体H1の構造解析戦略2011
- Author(s)
  島村達郎ら
- Organizer
  第84回日本生化学会大会(招待講演)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structural basis of secondary active transport in the sodium-hydantoin transporter Mhp1.2011
- Author(s)
  Shimamura T.
- Organizer
  The JSPS/iCeMS International Symposium.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] ヒダントイン輸送体Mhp1の基質輸送中の動き2011
- Author(s)
  島村達郎, 岩田想
- Organizer
  生理研研究会「作動中の膜機能分子の姿を捉える - 静止画から動画へ -」
- Place of Presentation
  岡崎
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] Structure of the human histamine H1 receptor with doxepin.2011
- Author(s)
  Shimamura T.
- Organizer
  International Union of Crystallography, XXII Congress and General Assembly.
- Place of Presentation
  Madrid, Spain.
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] ヒダントイン輸送体Mhp 1の基質輸送中の動き2011
- Author(s)
  島村達郎
- Organizer
  生理研研究会
- Place of Presentation
  岡崎
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] 二次性能動輸送体Mhp1の交互アクセス機構の解明2011
- Author(s)
  島村達郎
- Organizer
  2011年度日本生体エネルギー研究会
- Place of Presentation
  京都産業大学(京都府)
- Year and Date
  2011-12-21
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Structure of the human histamine H1 receptor with doxepin2011
- Author(s)
  Shimamura T., et al
- Organizer
  International Union of Crystallography, XXII Congress and General Assembly
- Place of Presentation
  マドリッド(スペイン)(招待講演)
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Crystal structure of the secondary-active transporter, Mhp1.2010
- Author(s)
  島村達郎
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Crystal structure of the secondary-active transporter, Mhp12010
- Author(s)
  Shimamura T, et al.
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] THREE CRYSTAL STRUCTURES REVEAL THE ALTERNATING ACCESS MECHANISM OF A SECONDARY ACTIVE TRANSPORTER, MHP12010
- Author(s)
  Shimamura T.
- Organizer
  The 3^<rd> Annual NIH Roadmap Meeting on Membrane Protein Technologies
- Place of Presentation
  アメリカ
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] Crystal structure of the secondary-active transporter2010
- Author(s)
  島村達郎
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] THREE CRYSTAL STRUCTURES REVEAL THE ALTERNATING ACCESS MECHANI M OF A SECONDARY ACTIVE TRANSPORTER2010
- Author(s)
  Shimamura T.
- Organizer
  The 3rd Annual NIH Roadmap Meeting on Membrane Protein Technologies
- Place of Presentation
  San Diego(USA)
- Data Source
  KAKENHI-PROJECT-21370043
[Presentation] ヒスタミンH１受容体の構造により解明された抗ヒスタミン薬選択性機構
- Author(s)
  島村達郎
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] ヒト由来ヒスタミンH１受容体の立体構造
- Author(s)
  島村達郎
- Organizer
  第９回　GPCR研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23657074
[Presentation] 膜蛋白質の結晶化
- Author(s)
  島村達郎
- Organizer
  第12回　日本蛋白質科学会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23657074

1. NOMURA Morimichi (10314246)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. OGASAWARA Satoshi (30546685)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. ASADA Hidetsugu (20399041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IWATA So (60452330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. TAKUYA Kobayashi (20311730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. SHIROISHI Mitsunori (00380527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. HINO Tomoya (40373360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TANAKA Yoshiki (10632333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ARAKAWA Takatoshi (30523766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUGA Hiroaki (00361668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMANAKA Yasuaki (10724049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. FUJIWARA Takaaki (70712751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Kimura Kanako (40726204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. YAJIMA SHUNSUKE (90301548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. TAKAYA Naoki (50282322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. YOHDA Masafumi (50250105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SASAKI Yasuyuki (50398814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. IM Dohyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. LEURS Rob

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAMASHITA Atsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. INOUE Asuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 浜窪隆雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 南後恵理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 久保稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 内田毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 加部泰明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 松森信明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 鈴木守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 神取秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimamura Tatsuro 島村 達郎

SHIMAMURA Tatsuro 島村 達郎

Research Projects

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無脊椎動物のGPCRの構造解析とリガンド探索Principal Investigator

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Structural analysis of amine receptors for the development of new antipsychotic drugs.Principal Investigator

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Challenges to the structural change analysis of G Protein-Coupled ReceptorsPrincipal Investigator

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Biased GPCR signaling mechanismPrincipal Investigator

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Structure determination of GPCRs using CryoEM.Principal Investigator

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Trial for determining the structure of CXCR7Principal Investigator

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Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodies

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Studies on the structure and function of a xenobiotic ABC transporter

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立体構造に基づくGPCRとリガンドの相互作用の解明Principal Investigator

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X-ray crystallographic analyses of human serotonin receptors for structure-based drug discovery.

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Structure determination of human membrane transportersPrincipal Investigator

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アロステリック抗体を用いたアデノシン受容体の構造解析Principal Investigator

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Structure determination of histamine H1 receptorPrincipal Investigator

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Shimamura Tatsuro 島村達郎

SHIMAMURA Tatsuro 島村達郎