Suga Hiroaki 菅裕明

… Alternative Names

Researcher Number	00361668
Other IDs
Affiliation (Current)	2021: 東京大学, 大学院理学系研究科(理学部), 教授
Affiliation (based on the past Project Information) *help	2016 – 2021: 東京大学, 大学院理学系研究科(理学部), 教授 2017: 東京大学, 大学院理学研究科, 教授 2016: 東京大学, 大学院理学系研究科, 教授 2016: 東京大学, 理学系研究科, 教授 2014 – 2016: 東京大学, 理学(系)研究科(研究院), 教授 … More
Review Section/Research Field	Principal Investigator Science and Engineering / Living organism molecular science / Chemistry / Biomolecular chemistry Except Principal Investigator Urology / ケミカルバイオロジー / Chemical biology / Science and Engineering / Bio-related chemistry / ケミカルバイオロジー … More
Keywords	Principal Investigator リボザイム / 特殊ペプチド / 翻訳 / ケミカルバイオロジー / RNA / 擬天然物 / ペプチド / RNA 触媒 / 分子進化 / RNA触媒 … More Except Principal Investigator ペプチド / 翻訳 / ケミカルバイオロジー / 特殊ペプチド / 遺伝記号 / tRNAアルシ化 / バイオフィルム / 抗バイオフィルム剤 / スクリーニング / 緑膿菌 / クォーラムセンシング / クオラムセンシング / 特殊環状ペプチド / modified Robbins device / Eikenella corrodens / 生合成リデザイン / 合成生物学 / 生合成工学 / 天然物化学 / 生物分子科学 / 薬剤探索 / 癌 / シグナル伝達 / シアリダーゼ / 人口触媒 / 糖転移 / ペルチド / 人工触媒 / キモカイン / トランスポーター / アミノ酸 / リボソーム / チオオキシカルボン酸 / 遺伝暗号 / tRNAアシル化 / チオオキシカルボン酸カルボン酸 / 尿路感染症 / 実験モデル系 / フローセル / 難治性尿路感染症 / 日和見感染菌 / in vitro実験モデル系 / in vivo実験モデル系 / 細菌 / 感染症 / アシネトバクター / 多剤耐性菌 / アウトブレイク / 新規治療法 / インフルエンザ / 感染阻害 / インフルエンザウイルス / HA蛋白質 / 抗ウイルス剤 / パントロピック / 増殖阻害 / オートインデューサー / オーラルバイオフィルム / Porphyromonas gingivalis / アンタゴニスト / LuxS遺伝子 / 細胞密度感知機構 / Porhyromonas gingivalis / アシルホモセリンラクトン / 共焦点レーザー顕微鏡 / 赤血球凝集 / 細胞外マトリックス / Modified Robbins device / 根尖性歯周炎 / 根尖孔外 / Quorum sensing / Autoinducer / Oral biofilm / Porphyromonas gingivalie / Antagonist / LuxS gene / Peptides / Macrocycles / membrane protein / ABC-transporter / RaPID selection / inhibitor / mRNA / translation / thioamide / チアゾール / 環状ペプチド / BNCT / macrocyclic peptides / RaPID / Bpa / Cba / hEGFR / ホウ素中性子 / RaPID System / mRNA display / quorum sensing / macrocyclic pepide / infectious deseases / macrocyclic peptide / infectious diseases / エピドラッグ / 白血病 / ペプチドライブラリ / ヒストンメチル化 / トランスレーショナルリサーチ / 遺伝子 / エピゲノム / 細胞増殖因子 / チロシンキナーゼ / 受容体 / サイトカイン / 増殖因子受容体 / 増殖因子 / HGF / MET / 発光タンパク質 / 光感受性タンパク質 / オプトジェネティクス / 発光基質 / ケミルミノジェネティクス / 化学発光タンパク質 / 難治性感染症 / 治療 / クオラムセンシング阻害剤 / オートインデューサーアナログ / 抗菌薬抵抗性 / リード化合物 / リアルタイムイメージング / 結晶構造解析 / Gタンパク質共役型受容体 / タンパク質 / G蛋白質共役型受容体 / 蛋白質 / FIT system / Foldamers / Macrocyclic peptides Less

特殊ペプチド・擬天然物創薬の命題への挑戦Principal Investigator
- Principal Investigator
  
  菅裕明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
ペプチドセレクションによる酵素ミミック創薬のための戦略Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
Synthetic biology of pseudo-natural products by artificial in vitro biosynthesisPrincipal Investigator
- Principal Investigator
  
  菅裕明
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
生合成リデザイン・研究総括班
- Principal Investigator
  
  阿部郁朗
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
チアゾール含有環状ペプチドの翻訳合成法Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
中性子捕捉療法を指向したホウ素含有環状ペプチドの開発Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
抗菌作用を発揮する大環状特殊ペプチドの発見と開発Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bio-related chemistry
- Research Institution
  The University of Tokyo
生合成リデザイン・国際活動支援班
- Principal Investigator
  
  阿部郁朗
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
薬剤活性向上した大環状ペプチドを開発する新規戦略Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Signal characteristics of heatero-receptor coupling and generation of artificial ligand
- Principal Investigator
  
  Matsumoto Kunio
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Trial for determining the structure of CXCR7
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
プロリル－４－ヒドロキシダーゼをアイソフォーム選択的に阻害する大環状化合物の発見Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Generation of minimal peptide catalysts based on the macrocyclic scaffoldPrincipal Investigator
- Principal Investigator
  
  Suga Hiroaki
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Innovation of chemiluminogenetics capable of noninvasive manipulation of biological functions deep inside body
- Principal Investigator
  
  Nagai Takeharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
低酸素誘導因子を阻害する特殊ペプチドの創出Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  ケミカルバイオロジー
- Research Institution
  The University of Tokyo
Ｋｅａｐ１－Ｎｒｆ２の相互作用を阻害する擬天然物特殊ペプチドのプロドラッグ化Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  ケミカルバイオロジー
- Research Institution
  The University of Tokyo
チオオキシ主鎖骨格ペプチドの翻訳合成技術の開発Host Researcher
- Host Researcher
  
  菅裕明
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  ケミカルバイオロジー
- Research Institution
  The University of Tokyo
Influenza viral hemagglutinin-targeted macrocyclic peptides as an antiviral agent
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Development of PPIs for a histone methyltransferase for leukemia therapy
- Principal Investigator
  
  OKADA YUKI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Analyses of mechanism of action of a quorum sensing inhibitor by using real-time imaging system
- Principal Investigator
  
  KARIYAMA REIKO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Okayama Gakuin University
  Okayama University
Development of novel methods for identifying antibiofilm agents against multidrug-resistant Acinetobacter baumannii
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
Non-standard peptide-probe discoveryPrincipal Investigator
- Principal Investigator
  
  SUGA Hiroaki
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  The University of Tokyo
擬天然物の翻訳プログラム合成と薬剤探索Principal Investigator
- Principal Investigator
  
  菅裕明
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Persistent biofilms in urinary tract infections -the development of novel methods for identifying antibiofilm agents-
- Principal Investigator
  
  UEHARA Shinya, 門田晃一
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Pseudomonas aeruginosa biofilms in urinary tract infections-the development of novelmethods for the search of antibiofilm agents-
- Principal Investigator
  
  KARIYAMA Reiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
The study on control technique of oral biofilms using a quorum sensing circuit
- Principal Investigator
  
  SHIGEYUKI Ebisu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
Generation of ribozymes that catalyze fatty acid biosynthesisPrincipal Investigator
- Principal Investigator
  
  SUGA Hiroaki
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo

[Book] 最新ペプチド合成技術とその創薬研究への応用2012
- Author(s)
  伊藤悠美、後藤佑樹、菅裕明
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Metal Ions in Life Sciences: Structural and Catalytic Roles of Metal Ions in RNA “Metal ion requirements in artificial ribozymes that catalyze aminoacylation and red-ox reactions”2012
- Author(s)
  H. Suga, K. Futai, K. Jin
- Publisher
  RSC Publishing
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Methods in Molecular Biology 848: Ribozymes Methods and Protocols “Flexizymes as a tRNA acylation tool facilitating genetic code reprogramming”2012
- Author(s)
  Y. Goto, H. Suga
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Metal Ions in Life Sciences : Structural and Catalytic Roles of Metal Ions in RNA "Metal ion requirements in artificial ribozymes that catalyze aminoacylation and redox reactions"2012
- Author(s)
  H.Suga, K.Futai, K.Jin
- Publisher
  RSC Publishing
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Methods in Molecular Biology 805 : Ribosome Display and Related Technologies "Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers"2012
- Author(s)
  P.Reid, Y.Goto, T.Katoh, H.Suga
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Methods in Molecular Biology 848 : Ribozymes Methods and Protocols "Flexizymesas a tRNA acylation tool facilitating genetic code reprogramming"2012
- Author(s)
  Y.Goto, H.Suga
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Methods in Molecular Biology 805: Ribosome Display and Related Technologies “Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers”2012
- Author(s)
  P. Reid, Y. Goto, T. Katoh, H. Suga
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-21000005
[Book] 核酸化学のニュートレンド2011
- Author(s)
  後藤佑樹、菅裕明
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-21000005
[Book] Quorum Sensing : Chapter 19 "Custom synthesis of antoinducers and their analogues"2010
- Author(s)
  J.Igarashi, H.Suga
- Publisher
  Humane Press
- Data Source
  KAKENHI-PROJECT-21000005
[Book] 鳥飼浩平2009
- Author(s)
  鳥飼浩平・菅裕明
- Publisher
  ファルマシア
- Data Source
  KAKENHI-PROJECT-16101007
[Book] セルアラカルト : ケミカルバイオロジーの夜明けから20年、潮流が大きな波に変わるには2009
- Author(s)
  菅裕明
- Publisher
  細胞工学
- Data Source
  KAKENHI-PROJECT-16101007
[Book] 「特殊ペプチドの翻訳合成と薬剤探索」新規素材探索-医薬品リード化合物・食品素材を求めて-2008
- Author(s)
  菅裕明・山岸祐介
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-16101007
[Book] 新創薬技術RAPIDシステムとマイクロ・ナノディバイスへの期待2008
- Author(s)
  村上裕・菅裕明
- Publisher
  化学工業
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides2021
- Author(s)
  Rogers Joseph M.、Nawatha Mickal、Lemma Betsegaw、Vamisetti Ganga B.、Livneh Ido、Barash Uri、Vlodavsky Israel、Ciechanover Aaron、Fushman David、Suga Hiroaki、Brik Ashraf
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 2 Pages: 513-522
- DOI
  10.1039/d0cb00179a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] In Vitro Selection of Macrocyclic d/l-Hybrid Peptides against Human EGFR2021
- Author(s)
  Imanishi Sayaka、Katoh Takayuki、Yin Yizhen、Yamada Mituhiro、Kawai Marina、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 143 Pages: 5680-5684
- DOI
  10.1021/jacs.1c02593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Affinity Maturation of Macrocyclic Peptide Modulators of Lys48‐Linked Diubiquitin by a Twofold Strategy2020
- Author(s)
  Huang Yichao、Nawatha Mickal、Livneh Ido、Rogers Joseph M.、Sun Hao、Singh Sumeet K.、Ciechanover Aaron、Brik Ashraf、Suga Hiroaki
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 26 Pages: 8022-8027
- DOI
  10.1002/chem.202000273
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Cyclic peptides can engage a single binding pocket through highly divergent modes2020
- Author(s)
  Patel Karishma、Walport Louise J.、Walshe James L.、Solomon Paul D.、Low Jason K. K.、Tran Daniel H.、Mouradian Kevork S.、Silva Ana P. G.、Wilkinson-White Lorna、Norman Alexander、Franck Charlotte、Matthews Jacqueline M.、Guss J. Mitchell、Payne Richard J.、Passioura Toby、Suga Hiroaki、Mackay Joel P.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Pages: 26728-26738
- DOI
  10.1073/pnas.2003086117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Chemoenzymatic Posttranslational Modification Reactions for the Synthesis of Psi[CH2 NH]-Containing Peptides2020
- Author(s)
  Kato Yasuharu、Kuroda Tomohiro、Huang Yichao、Ohta Risa、Goto Yuki、Suga Hiroaki
- Journal Title
  
  Angew Chem Int Ed Engl
  
  Volume: 59 Pages: 684-688
- DOI
  10.1002/anie.201910894
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19J14230, KAKENHI-PROJECT-20H05618
[Journal Article] Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display2020
- Author(s)
  Johansen-Leete Jason、Passioura Toby、Foster Simon R.、Bhusal Ram Prasad、Ford Daniel J.、Liu Minglong、Jongkees Seino A. K.、Suga Hiroaki、Stone Martin J.、Payne Richard J.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Pages: 9141-9146
- DOI
  10.1021/jacs.0c03152
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Discovery of quorum quenchers targeting the membrane-embedded sensor domain of theStaphylococcus aureusreceptor histidine kinase, AgrC2020
- Author(s)
  Xie Qian、Wiedmann Mareike M.、Zhao Aishan、Pagan Ivelisse R.、Novick Richard P.、Suga Hiroaki、Muir Tom W.
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Pages: 11223-11226
- DOI
  10.1039/d0cc04873a
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Exploring the Post-translational Enzymology of PaaA by mRNA Display2020
- Author(s)
  Fleming Steven R.、Himes Paul M.、Ghodge Swapnil V.、Goto Yuki、Suga Hiroaki、Bowers Albert A.
- Journal Title
  
  J Am Chem Soc
  
  Volume: 142 Pages: 5024-5028
- DOI
  10.1021/jacs.0c01576
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-20H05618
[Journal Article] Macrocyclic peptides that inhibit Wnt signallingviainteraction with Wnt3a.2020
- Author(s)
  Otero-Ramirez Manuel E.、Matoba Kyoko、Mihara Emiko、Passioura Toby、Takagi Junichi、Suga Hiroaki
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 1 Pages: 26-34
- DOI
  10.1039/d0cb00016g
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455
[Journal Article] GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf2020
- Author(s)
  Zhang Ziyang、Gao Rong、Hu Qi、Peacock Hayden、Peacock D. Matthew、Dai Shizhong、Shokat Kevan M.、Suga Hiroaki
- Journal Title
  
  ACS Central Science
  
  Volume: 6 Pages: 1753-1761
- DOI
  10.1021/acscentsci.0c00514
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Initiating ribosomal peptide synthesis with exotic building blocks2020
- Author(s)
  Tsiamantas Christos、Rogers Joseph M.、Suga Hiroaki
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Pages: 4265-4272
- DOI
  10.1039/d0cc01291b
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code2020
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Pages: 4965-4969
- DOI
  10.1021/jacs.9b12280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-20H05618
[Journal Article] Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages2020
- Author(s)
  Tsiamantas Christos、Kwon Sunbum、Rogers Joseph M.、Douat Cline、Huc Ivan、Suga Hiroaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Pages: 4860-4864
- DOI
  10.1002/anie.201914654
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H05618
[Journal Article] An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch2020
- Author(s)
  Ishida Satoshi、Terasaka Naohiro、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 16 Pages: 702-709
- DOI
  10.1038/s41589-020-0500-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16200, KAKENHI-PROJECT-20H05618
[Journal Article] Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy2020
- Author(s)
  Hazama Daisuke、Yin Yizhen、Murata Yoji、Matsuda Makoto、Okamoto Takeshi、Tanaka Daisuke、Terasaka Naohiro、Zhao Jinxuan、Sakamoto Mariko、Kakuchi Yuka、Saito Yasuyuki、Kotani Takenori、Nishimura Yoshihiro、Nakagawa Atsushi、Suga Hiroaki、Matozaki Takashi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 27
- DOI
  10.1016/j.chembiol.2020.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H04032
[Journal Article] Ribosomal Elongation of Aminobenzoic Acid Derivatives2020
- Author(s)
  Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Pages: 16518-16522
- DOI
  10.1021/jacs.0c05765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080
[Journal Article] Minimal lactazole scaffold for in vitro thiopeptide bioengineering2020
- Author(s)
  Vinogradov Alexander A.、Shimomura Morito、Goto Yuki、Ozaki Taro、Asamizu Shumpei、Sugai Yoshinori、Suga Hiroaki、Onaka Hiroyasu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Pages: 1-13
- DOI
  10.1038/s41467-020-16145-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18K05385
[Journal Article] Introduction to Thiopeptides: Biological Activity, Biosynthesis, and Strategies for Functional Reprogramming2020
- Author(s)
  Vinogradov Alexander A.、Suga Hiroaki
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 27 Pages: 1032-1051
- DOI
  10.1016/j.chembiol.2020.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Design, Synthesis, and Conformation?Activity Study of Unnatural Bridged Bicyclic Depsipeptides as Highly Potent Hypoxia Inducible Factor-1 Inhibitors and Antitumor Agents2020
- Author(s)
  Koike Kota、Nagano Masanobu、Ebihara Masahiro、Hirayama Tasuku、Tsuji Mieko、Suga Hiroaki、Nagasawa Hideko
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 63 Pages: 4022-4046
- DOI
  10.1021/acs.jmedchem.9b02039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids2020
- Author(s)
  Katoh Takayuki、Sengoku Toru、Hirata Kunio、Ogata Kazuhiro、Suga Hiroaki
- Journal Title
  
  Nature Chemistry
  
  Volume: 12 Pages: 1081-1088
- DOI
  10.1038/s41557-020-0525-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18K19305
[Journal Article] Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display2020
- Author(s)
  Vinogradov Alexander A.、Nagai Emiko、Chang Jun Shi、Narumi Kakeru、Onaka Hiroyasu、Goto Yuki、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Pages: 20329-20334
- DOI
  10.1021/jacs.0c10374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation.2020
- Author(s)
  Bashiruddin Nasir K.、Hayashi Mikihito、Nagano Masanobu、Wu Yan、Matsunaga Yukiko、Takagi Junichi、Nakashima Tomoki、Suga Hiroaki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Pages: 31070-31077
- DOI
  10.1073/pnas.2012266117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-20H00551
[Journal Article] Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A2020
- Author(s)
  Vinogradov Alexander A.、Shimomura Morito、Kano Naokazu、Goto Yuki、Onaka Hiroyasu、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Pages: 13886-13897
- DOI
  10.1021/jacs.0c05541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05618
[Journal Article] Discovery of Functional Macrocyclic Peptides by Means of the RaPID System2019
- Author(s)
  Tsiamantas Christos、Otero-Ramirez Manuel E.、Suga Hiroaki
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2001 Pages: 299-315
- DOI
  10.1007/978-1-4939-9504-2_14
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] In Vitro Biosynthesis of Peptides Containing Exotic Azoline Analogues2019
- Author(s)
  Goto Yuki、Suga Hiroaki
- Journal Title
  
  Chembiochem
  
  Volume: 21 Pages: 84-87
- DOI
  10.1002/cbic.201900521
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382
[Journal Article] Flexizyme-Enabled Benchtop Biosynthesis of Thiopeptides2019
- Author(s)
  Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Pages: 758-762
- DOI
  10.1021/jacs.8b11521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
[Journal Article] Ribosomal Formation of Thioamide Bonds in Polypeptide Synthesis2019
- Author(s)
  Maini Rumit、Kimura Hiroyuki、Takatsuji Ryo、Katoh Takayuki、Goto Yuki、Suga Hiroaki
- Journal Title
  
  J Am Chem Soc
  
  Volume: 141 Pages: 20004-20008
- DOI
  10.1021/jacs.9b11097
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382
[Journal Article] De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor2019
- Author(s)
  Yin Yizhen、Ochi Nobuaki、Craven Timothy W.、Baker David、Takigawa Nagio、Suga Hiroaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Pages: 19193-19197
- DOI
  10.1021/jacs.9b09106
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] Flexizyme-catalyzed synthesis of 3′-aminoacyl-NH-tRNAs2019
- Author(s)
  Katoh T, Suga H.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: pii
- DOI
  10.1093/nar/gkz143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-18H02080
[Journal Article] Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation2019
- Author(s)
  Yin Y, Fei Q, Liu W, Li Z, Suga H, Wu C.
- Journal Title
  
  Angew Chem Int Ed Engl.
  
  Volume: 58 Pages: 4880-4885
- DOI
  10.1002/anie.201813827
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16F16412
[Journal Article] Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges2019
- Author(s)
  Vinogradov AA, Yin Y, Suga H.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Pages: 4167-4181
- DOI
  10.1021/jacs.8b13178
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444
[Journal Article] In vitro expression of genetically encoded non-standard peptides consisting of exotic amino acid building blocks2019
- Author(s)
  Hirose H, Tsiamantas C, Katoh T, Suga H.
- Journal Title
  
  Current Opinions in Biotechnology
  
  Volume: 58 Pages: 26-28
- DOI
  10.1016/j.copbio.2018.10.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18F18727
[Journal Article] Ribosomal Synthesis of Backbone-Cyclic Peptides Compatible with In Vitro Display2019
- Author(s)
  Takatsuji R, Shinbara K, Katoh T, Goto Y, Passioura T, Yajima R, Komatsu Y, Suga H.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Pages: 2279-2287
- DOI
  10.1021/jacs.8b05327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
[Journal Article] RiPP生合成経路の改変による人工ペプチド生産2019
- Author(s)
  後藤佑樹、井上澄香、菅裕明
- Journal Title
  
  FARUAW
  
  Volume: 55 Issue: 7 Pages: 662-667
- DOI
  10.14894/faruawpsj.55.7_662
- NAID
  130007671606
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382
[Journal Article] A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display2019
- Author(s)
  Hirose Hisaaki、Hideshima Tomoki、Katoh Takayuki、Suga Hiroaki
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Pages: 2089-2100
- DOI
  10.1002/cbic.201900039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation2019
- Author(s)
  Tsiamantas Christos、Kwon Sunbum、Douat C?line、Huc Ivan、Suga Hiroaki
- Journal Title
  
  Chemical Communications
  
  Volume: 55 Pages: 7366-7369
- DOI
  10.1039/c9cc03547h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease.2019
- Author(s)
  Nitsche C, Passioura T, Varava P, Mahawaththa MC, Leuthold MM, Klein CD, Suga H, Otting G.
- Journal Title
  
  ACS Med Chem Lett.
  
  Volume: 10 Pages: 168-174
- DOI
  10.1021/acsmedchemlett.8b00535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Max-Bergmann award lecture:A RaPID way to discover bioactive nonstandard peptides assisted by the flexizyme and FIT systems2018
- Author(s)
  Suga H
- Journal Title
  
  Drug Discov Today Technol.
  
  Volume: 24
- DOI
  10.1002/psc.3055
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate2018
- Author(s)
  Bacusmo JM, Kuzmishin AB, Cantara WA, Goto Y, Suga H, Musier-Forsyth K.
- Journal Title
  
  RNA Biol.
  
  Volume: 15 Pages: 1-10
- DOI
  10.1080/15476286.2017.1353846
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
[Journal Article] RNA Display Methods for the Discovery of Bioactive Macrocycles2018
- Author(s)
  Huang Y, Wiedmann MM, Suga H.
- Journal Title
  
  Chemical Reviews
  
  Volume: XX
- DOI
  10.1021/acs.chemrev.8b00430
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16F16810
[Journal Article] Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1.2018
- Author(s)
  Bashiruddin Nasir K.、Matsunaga Yukiko、Nagano Masanobu、Takagi Junichi、Suga Hiroaki
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 29 Pages: 1847-1851
- DOI
  10.1021/acs.bioconjchem.8b00219
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H01420
[Journal Article] Engineering of RiPP pathways for the production of artificial peptides bearing various non-proteinogenic structures.2018
- Author(s)
  Goto Yuki、Suga Hiroaki
- Journal Title
  
  Curr Opin Chem Biol.
  
  Volume: 46 Pages: 82-90
- DOI
  10.1016/j.cbpa.2018.06.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
[Journal Article] Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A.2018
- Author(s)
  Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H.
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 26 Pages: 1225-1231
- DOI
  10.1016/j.bmc.2018.01.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
[Journal Article] tRNA engineering for manipulating genetic code.2018
- Author(s)
  Katoh T, Iwane Y, Suga H.
- Journal Title
  
  RNA Biol.
  
  Volume: 15 Pages: 453-460
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Ribosomal Incorporation of Consecutive β-Amino Acids2018
- Author(s)
  Katoh T, Suga H.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Pages: 12159-12167
- DOI
  10.1021/jacs.8b07247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080
[Journal Article] Artificial <i>In Vitro</i> Biosynthesis Systems for the Development of Pseudo-Natural Products2018
- Author(s)
  Goto Yuki、Suga Hiroaki
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 91 Issue: 3 Pages: 410-419
- DOI
  10.1246/bcsj.20170379
- NAID
  130006507065
- ISSN
  0009-2673, 1348-0634
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-16H01131, KAKENHI-PUBLICLY-18H04382
[Journal Article] Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist.2018
- Author(s)
  Miao Wenyu、Sakai Katsuya、Ozawa Naoya、Nishiuchi Takumi、Suzuki Yoshinori、Ito Kenichiro、Morioka Tomomi、Umitsu Masataka、Takagi Junichi、Suga Hiroaki、Matsumoto Kunio
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Pages: 16492-16492
- DOI
  10.1038/s41598-018-34835-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-16K08544, KAKENHI-PROJECT-16J05654
[Journal Article] Non-competitive cyclic peptides for targeting enzyme-substrate complexes2018
- Author(s)
  McAllister T. E.、Yeh T.-L.、Abboud M. I.、Leung I. K. H.、Hookway E. S.、King O. N. F.、Bhushan B.、Williams S. T.、Hopkinson R. J.、M?nzel M.、Loik N. D.、Chowdhury R.、Oppermann U.、Claridge T. D. W.、Goto Y.、Suga H.、Schofield C. J.、Kawamura A.
- Journal Title
  
  Journal of Chemical Science
  
  Volume: 9 Pages: 4569-4578
- DOI
  10.1039/c8sc00286j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
[Journal Article] Display Selection of Exotic Macrocyclic Peptides Expressed under a Radically Reprogrammed 23 Amino Acid Genetic Code.2018
- Author(s)
  Passioura T, Liu W, Dunkelmann D, Higuchi T, Suga H.
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 140 Pages: 11551-11555
- DOI
  10.1021/jacs.8b03367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity.2018
- Author(s)
  Nishio Kosuke、Belle Roman、Katoh Takayuki、Kawamura Akane、Sengoku Toru、Hanada Kazuharu、Ohsawa Noboru、Shirouzu Mikako、Yokoyama Shigeyuki、Suga Hiroaki
- Journal Title
  
  Chembiochem.
  
  Volume: 19 Pages: 979-985
- DOI
  10.1002/cbic.201800047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16H03293
[Journal Article] De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry2018
- Author(s)
  Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T.
- Journal Title
  
  Cell Chem Biol
  
  Volume: 25 Pages: 30125-30129
- DOI
  10.1016/j.chembiol.2018.04.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] Nonproteinogenic deep mutational scanning of linear and cyclic peptides.2018
- Author(s)
  Rogers JM, Passioura T, Suga H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 115 Pages: 10959-10964
- DOI
  10.1073/pnas.1809901115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis.2018
- Author(s)
  Decoene KW, Vannecke W, Passioura T, Suga H, Madder A.
- Journal Title
  
  Biomedicines.
  
  Volume: 6
- DOI
  10.3390/biomedicines6040099
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands.2018
- Author(s)
  Otero-Ramirez ME, Passioura T, Suga H.
- Journal Title
  
  Biomedicines.
  
  Volume: 6
- DOI
  10.3390/biomedicines6040116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Genetic code expansion via integration of redundant amino acid assignment by finely tuning tRNA pools.2018
- Author(s)
  Tajima K, Katoh T, Suga H.
- Journal Title
  
  Curr Opin Chem Biol.
  
  Volume: 46 Pages: 212-218
- DOI
  10.1016/j.cbpa.2018.07.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids.2018
- Author(s)
  Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I.
- Journal Title
  
  Nat Chem.
  
  Volume: 10 Pages: 405-412
- DOI
  10.1038/s41557-018-0007-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
[Journal Article] Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors2018
- Author(s)
  Kusakizako T, Tanaka Y, Hipolito CJ, Suga H, Nureki O.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1700 Pages: 37-57
- DOI
  10.1007/978-1-4939-7454-2_3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16H06294
[Journal Article] MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner2018
- Author(s)
  Miao W, Sakai K, Imamura R, Ito K, Suga H, Sakuma T, Yamamoto T, Matsumoto K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Pages: 3141-3141
- DOI
  10.3390/ijms19103141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16K08544
[Journal Article] Artificial Division of Codon Boxes for Expansion of the Amino Acid Repertoire of Ribosomal Polypeptide Synthesis2018
- Author(s)
  Iwane Y, Katoh T, Goto Y, Suga H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1728 Pages: 17-47
- DOI
  10.1007/978-1-4939-7574-7_2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
[Journal Article] Macrocyclic peptide inhibitors for the protein?protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 52017
- Author(s)
  Song X, Lu LY, Passioura T, Suga H.
- Journal Title
  
  Org Biomol Chem.
  
  Volume: 15 Pages: 5155-5160
- DOI
  10.1039/c7ob00012j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
[Journal Article] A <i>Pseudomonas aeruginosa</i> Quorum-Sensing autoinducer analog enhances the activity of antibiotics against resistant strains2017
- Author(s)
  T. Amoh, K. Murakami, R. Kariyama, K. Hori, D. Viducic, K. Hirota, J. Igarashi, H. Suga, H. Kumon, Y. Miyake
- Journal Title
  
  The Journal of Medical Investigation
  
  Volume: 64 (1, 2) Issue: 1.2 Pages: 101-109
- DOI
  10.2152/jmi.64.101
- NAID
  130005501959
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461512
[Journal Article] Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo.2017
- Author(s)
  9.Ozaki, T., Yamashita, K., Goto, Y., Shimomura, M., Hayashi, S., Asamizu, S., Sugai, Y., Ikeda, H., Suga, H., Onaka, H.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Pages: 14207-14207
- DOI
  10.1038/ncomms14207
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PLANNED-16H06444
[Journal Article] Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance.2017
- Author(s)
  Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
- Journal Title
  
  Nature communications
  
  Volume: 7 Pages: 11030-11030
- DOI
  10.1038/ncomms11030
- NAID
  130007529314
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-16H06145
[Journal Article] Strategies for transitioning macrocyclic peptides to cell-permeable drug leads2017
- Author(s)
  L.J. Walport, R. Obexer, H. Suga
- Journal Title
  
  Curr Opin Biotechnol.
  
  Volume: 48 Pages: 242-250
- DOI
  10.1016/j.copbio.2017.07.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15F15333, KAKENHI-PROJECT-26220204
[Journal Article] Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.2017
- Author(s)
  Yu H, Dranchak P, Li Z, MacArthur R, Munson MS, Mehzabeen N, Baird NJ, Battalie KP, Ross D, Lovell S, Carlow CK, Suga H, Inglese J.
- Journal Title
  
  Nat Commun.
  
  Volume: 8 Pages: 14932-14932
- DOI
  10.1038/ncomms14932
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] Conformational and chemical selection by a trans-acting editing domain2017
- Author(s)
  Danhart EM, Bakhtina M, Cantara WA, Kuzmishin AB, Ma X, Sanford BL, Vargas-Rodriguez O, Ko; M, Goto Y, Suga H, Nakanishi K, Micura R, Foster MP, Musier-Forsyth K.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114
- DOI
  10.1073/pnas.1703925114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
[Journal Article] tRNA engineering for manipulating genetic code2017
- Author(s)
  Katoh Takayuki、Iwane Yoshihiko、Suga Hiroaki
- Journal Title
  
  RNA Biol.
  
  Volume: 0 Pages: 1-8
- DOI
  10.1080/15476286.2017.1343227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Effects of an autoinducer analogue on antibiotic tolerance in Pseudomonas aeruginosa.2017
- Author(s)
  T. Amoh, K. Murakami, R. Kariyama, K. Hori, D. Viducic, K. Hirota, J. Igarashi, H. Suga, H. Kumon, Y. Miyake
- Journal Title
  
  J Antimicrob Chemother
  
  Volume: 印刷中
- DOI
  10.1093/jac/dkx132
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461512
[Journal Article] Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads2017
- Author(s)
  R. Obexer, L.J. Walport, H. Suga
- Journal Title
  
  Curr Opin Chem Biol.
  
  Volume: 38 Pages: 52-61
- DOI
  10.1016/j.cbpa.2017.02.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15F15333, KAKENHI-PROJECT-26220204
[Journal Article] Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation.2017
- Author(s)
  Katoh T, Iwane Y, Suga H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 45 Pages: 12601-12610
- DOI
  10.1093/nar/gkx1129
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
[Journal Article] Highly selective inhibition of histone demethylases by de novo macrocyclic peptides2017
- Author(s)
  Kawamura A, Mnzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Muller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ.
- Journal Title
  
  Nat. Commun.
  
  Volume: 8 Pages: 14773-14773
- DOI
  10.1038/ncomms14773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
[Journal Article] Linker-free incorporation of carbohydrates into in vitro displayed macrocyclic peptides.2017
- Author(s)
  Jongkees SAK, Umemoto S, Suga H
- Journal Title
  
  Chem Sci.
  
  Volume: 8 Pages: 1474-1481
- DOI
  10.1039/c6sc04381j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets2017
- Author(s)
  Passioura T and Suga H
- Journal Title
  
  Chem Commun (Camb).
  
  Volume: 53 Pages: 1931-1940
- DOI
  10.1039/c6cc06951g
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16558, KAKENHI-PROJECT-26220204
[Journal Article] Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides2017
- Author(s)
  Jongkees Seino A.K.、Caner Sami、Tysoe Christina、Brayer Gary D.、Withers Stephen G.、Suga Hiroaki
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 24 Pages: 381-390
- DOI
  10.1016/j.chembiol.2017.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Efficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-Targeting2017
- Author(s)
  Sakurai Y, Mizumura W, Murata M, Hada T, Yamamoto S, Ito K, Iwasaki K, Katoh T, Goto Y, Takagi A, Kohara M, Suga H, Harashima H.
- Journal Title
  
  Mol Pharm
  
  Volume: 14 Pages: 3290-3298
- DOI
  10.1021/acs.molpharmaceut.7b00362
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
[Journal Article] Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides.2017
- Author(s)
  Jongkees SAK, Caner S, Tysoe C, Brayer GD, Withers SG, Suga H.
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 16 Pages: 381-390
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Journal Article] Consecutive Elongation of D-Amino Acids in Translation2017
- Author(s)
  Katoh T, Tajima K, Suga H.
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 24 Pages: 46-54
- DOI
  10.1016/j.chembiol.2016.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
[Journal Article] tRid, an enabling method to isolate previously inaccessible small RNA fractions2016
- Author(s)
  Kazuki Futai, Naohiro Terasaka, Takayuki Katoh, Hiroaki Suga.
- Journal Title
  
  Methods.
  
  Volume: 106 Pages: 105-111
- DOI
  10.1016/j.ymeth.2016.04.033
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
[Journal Article] Ribosome-mediated synthesis of natural product-like peptides via cell-free translation2016
- Author(s)
  Rumit Maini
- Journal Title
  
  Current opinion in chemical biology
  
  Volume: 34 Pages: 44-52
- DOI
  10.1016/j.cbpa.2016.06.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16033, KAKENHI-PROJECT-26220204
[Journal Article] Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent.2016
- Author(s)
  Takanori Nakane, Shinya Hanashima, Mamoru Suzuki, Haruka Saiki, Taichi Hayashi, Keisuke Kakinouchi, Shigeru Sugiyama, Satoshi Kawatake, Shigeru Matsuoka, Nobuaki Matsumori, et al
- Journal Title
  
  PNAS
  
  Volume: 113 Pages: 13039-13044
- DOI
  10.1073/pnas.1602531113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-26840021, KAKENHI-PROJECT-15K18487
[Journal Article] Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling2016
- Author(s)
  Katoh Takayuki、Wohlgemuth Ingo、Nagano Masanobu、Rodnina Marina V.、Suga Hiroaki
- Journal Title
  
  Nature Communications
  
  Volume: 7 Pages: 11657-11657
- DOI
  10.1038/ncomms11657
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes2016
- Author(s)
  Yoshihiko Iwane, Azusa Hitomi, Hiroshi Murakami, Takayuki Katoh, Yuki Goto, and Hiroaki Suga
- Journal Title
  
  Nature Chemistry
  
  Volume: 8 Pages: 317-325
- DOI
  10.1038/nchem.2446
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J09576, KAKENHI-PROJECT-26220204
[Journal Article] A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX2016
- Author(s)
  Naohiro Terasaka, Kazuki Futai, Takayuki Katoh, Hiroaki Suga.
- Journal Title
  
  RNA
  
  Volume: 22 Pages: 1341-1350
- DOI
  10.1261/rna.057737.116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
[Journal Article] A three-dimensional movie of structural changes in bacteriorhodopsin.2016
- Author(s)
  Nango, E., Royant, A.†, Kubo, M.† et al. (†equal contribution)(45名中2番目)
- Journal Title
  
  Nature
  
  Volume: 354 Pages: 1552-1557
- DOI
  10.1126/science.aah3497
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01055, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18486, KAKENHI-PROJECT-15K18523, KAKENHI-PROJECT-16H06315
[Journal Article] "Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection."2015
- Author(s)
  Jongkees, S. A. K.; Hipolito, C. J.; Rogers, J. M.; Suga, H.
- Journal Title
  
  New Journal of Chemistry
  
  Volume: unknown
- DOI
  10.1039/c4nj01633e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03766
[Journal Article] Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides.2015
- Author(s)
  Naohiro Terasaka, Yoshihiko Iwane, Anna-Skrollan Geiermann, Yuki Goto & Hiroaki Suga
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 16 Pages: 6513-6531
- DOI
  10.3390/ijms16036513
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J08188, KAKENHI-PROJECT-14J09576, KAKENHI-PROJECT-26220204
[Journal Article] Selection-based discovery of macrocyclic peptides for the next generation therapeutics2015
- Author(s)
  T. Morita N.D. Loik C.J. Hipolito Y. Goto H. Suga
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 26 Pages: 34-41
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14F04065
[Journal Article] Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection2015
- Author(s)
  Seino A. K. Jongkees, Christopher J. Hipolito, Joseph M. Rogers, Hiroaki Suga
- Journal Title
  
  New Journal of Chemistry
  
  Volume: unknown
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03026
[Journal Article] Synthesis of Fused Tricyclic Peptides using a Reprogrammed Translation System and Chemical Modification2015
- Author(s)
  N.K. Bashiruddin; M. Nagano; H. Suga
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 61 Pages: 45-50
- DOI
  10.1016/j.bioorg.2015.06.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-13J03534
[Journal Article] Selection-based discovery of macrocyclic peptides for the next generation therapeutics.2015
- Author(s)
  T. Morioka; N.D. Loik; C.J. Hipolito; Y. Goto; H. Suga
- Journal Title
  
  Curr Opin Chem Biol
  
  Volume: 26C Pages: 34-41
- DOI
  10.1016/j.cbpa.2015.01.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-15H06073
[Journal Article] Diverse application platform for hard X-ray diffraction in SACLA (DAPHNIS): application to serial protein crystallography using an X-ray free-electron laser2015
- Author(s)
  Tono K, Shimamura T, et al.
- Journal Title
  
  J Synchrotron Radiat.
  
  Volume: 22 Pages: 532-537
- DOI
  10.1107/s1600577515004464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-25650023, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15H04338
[Journal Article] A Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAM.2015
- Author(s)
  Iwasaki, K. Goto, Y. Katoh, T. Yamashita, T. Kaneko, S. Suga, H.
- Journal Title
  
  Journal of molecular evolution
  
  Volume: 81 Pages: 210-217
- DOI
  10.1007/s00239-015-9710-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12739, KAKENHI-PROJECT-26220204
[Journal Article] Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides2015
- Author(s)
  Naohiro Terasaka, Yoshihiko Iwane, Anna-Skrollan Geiermann, Yuki Goto and Hiroaki Suga,
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 16(3) Pages: 6513-6531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03730
[Journal Article] Artificial human Met agonists based on macrocycle scaffolds.2015
- Author(s)
  Ito K, Sakai K, Suzuki Y, Ozawa N, Hatta T, Natsume T, Matsumoto K, Suga H.
- Journal Title
  
  Nature communications
  
  Volume: 6 Pages: 6373-6373
- DOI
  10.1038/ncomms7373
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-15K14473, KAKENHI-PROJECT-26220204
[Journal Article] De novo native sulfur/chlorine SAD phasing for serial femtosecond crystallography.2015
- Author(s)
  Nakane T, Song C, Suzuki M, Nango E, Kobayashi J, Masuda T, Inoue S, Mizohata E, Nakatsu T, Tanaka T, Tanaka R, Shimamura T, Tono K, Joti Y, Kameshima T, Hatsui T, Yabashi M, Nureki O, Iwata S, Sugahara M.
- Journal Title
  
  Acta Crystallogr. D
  
  Volume: 71 Pages: 2519-1525
- DOI
  10.1107/s139900471501857x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440028, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25450167, KAKENHI-PROJECT-15K14941, KAKENHI-PROJECT-25650026
[Journal Article] Flexizymes-facilitated genetic code reprogramming leading to the discovery of drug-like peptides2014
- Author(s)
  N. Terasaka, H. Suga
- Journal Title
  
  Chemistry Letters
  
  Volume: 43 Pages: 11-19
- NAID
  130004427082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Reprogramming the genetic code in vitro2014
- Author(s)
  T. Passioura; H. Suga
- Journal Title
  
  Trends in Biochemical Sciences
  
  Volume: 39 Pages: 400-408
- DOI
  10.1016/j.tibs.2014.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] Selection-based discovery of druglike macrocyclic peptides2014
- Author(s)
  T. Passioura, T. Katoh, Y. Goto, H. Suga
- Journal Title
  
  Selection-based discovery of druglike macrocyclic peptides
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase2014
- Author(s)
  Y. Goto, Y. Ito, Y. Kato, S. Tsunoda, H. Suga*
- Journal Title
  
  Chemistry and Biology
  
  Volume: (in press)(未確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change2014
- Author(s)
  K. Yamagata, Y. Goto, H. Nishimasu, J. Morimoto, R. Ishitani, N. Dohmae, N. Takeda, R. Nagai, I. Komuro, H. Suga, O. Nureki
- Journal Title
  
  Structure
  
  Volume: 22 Pages: 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog2014
- Author(s)
  A. Kodan, T. Yamaguchi, T. Nakatsu, K. Sakiyama, C.J. Hipolito, A. Fujioka, R. Hirokane, K. Ikeguchi, B. Watanabe,J. Hiratake, Y. Kimura, H. Suga, K. Ueda, H. Kato
- Journal Title
  
  Pro. Nat. Acad. Sci
  
  Volume: 111 Pages: 4049-4054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Protein cocrystallization molecules originating from in vitro selected macrocyclic peptides2014
- Author(s)
  C.J. Hipolito, N.K. Bashiruddin, H. Suga
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 26 Pages: 24-31
- DOI
  10.1016/j.sbi.2014.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Selection-based discovery of druglike macrocyclic peptides2014
- Author(s)
  T. Passioura, T. Katoh, Y. Goto, H. Suga
- Journal Title
  
  Annual Review in Biochemistry
  
  Volume: (in press)(未確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Construction and screening of vast libraries of natural product-like macrocyclic peptides using in vitro display technologies2014
- Author(s)
  N.K. Bashiruddin; H. Suga
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 24C Pages: 131-138
- DOI
  10.1016/j.cbpa.2014.11.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220204
[Journal Article] An orthogonal ribosome-tRNAs pair via the engineering of peptidyl transferase center2014
- Author(s)
  N. Terasaka, G. Hayashi1, T. Katoh, and H. Suga
- Journal Title
  
  Nature Chemical Biology
  
  Volume: (in press)
- NAID
  120006348461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] An orthogonal ribosome-tRNAs pair via the engineering of peptidyl transferase center2014
- Author(s)
  N. Terasaka, G. Hayashil, T. Katoh, and H. Suga
- Journal Title
  
  Nature Chemical Biology
  
  Volume: (in press)(未確定)
- NAID
  120006348461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase SIRT22014
- Author(s)
  Y. Goto, Y. Ito, Y. Kato, S. Tsunoda, H. Suga
- Journal Title
  
  Chemistry and Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog2014
- Author(s)
  A. Kodan, T. Yamaguchi, T. Nakatsu, K. Sakiyama, C. J. Hipolito, A. Fujioka, R. Hirokane, K. Ikeguchi, B. Watanabe, J. Hiratake, Y. Kimura, H. Suga, K. Ueda, H. Kato
- Journal Title
  
  Pro. Nat. Acad. Sci.
  
  Volume: 111(未確定) Pages: 4049-4054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Technologies for the synthesis of mRNA-encoding libraries and discovery of bioactive natural product-inspired non-traditional macrocyclic peptides2013
- Author(s)
  Kenichiro Ito, Toby Pass ioura. Hiroaki Suga
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 3502-3528
- DOI
  10.3390/molecules18033502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07727, KAKENHI-PROJECT-21000005
[Journal Article] In Vitro Selection of Multiple Libraries Created by Genetic Code Reprogramming To Discover Macrocyclic Peptides That Antagonize VEGFR2 Activity in Living Cells2013
- Author(s)
  T. Kawakami, T. Ishizawa, T. Fujino, P.C. Reid, H. Suga, H. Murakami
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 8 Pages: 1205-1514
- DOI
  10.1021/cb300697h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Flexizyme-mediated genetic reprogramming as a tool for noncanonical Peptide synthesis and drug discovery2013
- Author(s)
  Y. Tanaka, C.J. Hipolito, A.D. Maturana, K. Ito, T. Kuroda, T. Higuchi, T. Katoh, H.E. Kato, M. Hattori, K. Kumazaki, T. Tsukazaki, R. Ishitani, H. Suga, O. Nureki
- Journal Title
  
  Chemistry European Journal
  
  Volume: 496 Pages: 247-251
- DOI
  10.1002/chem.201300247
- NAID
  120005716854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Structural basis for the novel mechanism of drug extrusion by a MATE multidrug transporter.2013
- Author(s)
  Y・ Tanaka, C・J・ Hipolito, A・D・ Maturana, K・ Ito, T・ Kuroda, T・ Higuchi, T・ Katoh, H・E・ Kato, M・ Hattori, K・ Kumazaki, T・ Tsukazaki, R・ Ishitani, H・ Suga, O・ Nureki
- Journal Title
  
  Nature
  
  Volume: 496 Pages: 247-251
- DOI
  10.1038/nature12014
- NAID
  120005716854
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-21000005, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-24121704, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24570150, KAKENHI-PROJECT-24681047, KAKENHI-PROJECT-24687016, KAKENHI-PROJECT-25291011
[Journal Article] Nonstandard peptide expression under the genetic code consisting of reprogrammed dual sense codons.2013
- Author(s)
  Y. Goto, M. Iseki, A. Hitomi, H. Murakami, and H. Suga
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 8 Pages: 2630-2634
- DOI
  10.1021/cb400549p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24655146
[Journal Article] Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation2013
- Author(s)
  M. Das, O. Vargas-Rodriguez, Y. Goto, H. Suga, K. Museir-Forsyth
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 未確定
- DOI
  10.1093/nar/gkt1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter2013
- Author(s)
  C・J・ Hipolito, Y・Tanaka, T・ Katoh, O・ Nureki, H・ Suga
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 10514-10530
- DOI
  10.3390/molecules180910514
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24681047
[Journal Article] Reevaluation of the D-amino acid compatibility with the elongation event in translation2013
- Author(s)
  T. Fujino, Y. Goto, H. Suga, H. Murakami
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Pages: 1830-1837
- DOI
  10.1021/ja309570x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24655146
[Journal Article] In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors2012
- Author(s)
  Hayashi, Y.; Morimoto, J.: Suga, H.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 7 Pages: 607-613
- DOI
  10.1021/cb200388k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
[Journal Article] In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform- Selective Inhibitors2012
- Author(s)
  Y. Hayashi, J. Morimoto, H. Suga*
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 7 Pages: 607-613
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal production and in vitro selection of natural product-like peptidomimetics: The FIT and RaPID systems2012
- Author(s)
  C. J. Hipolito, H. Suga*
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 16 Pages: 196-203
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Selective thioether macrocyclization of peptides having the N-terminal 2- chloroacetyl group and competing two or three cysteine residues in translation2012
- Author(s)
  Kazuhiro Iwasaki, Yuki Goto, Takayuki Katoh, Hiroaki Suga
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 10 Pages: 5783-5786
- DOI
  10.1039/c2ob25306b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J09695, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145, KAKENHI-PROJECT-24655146, KAKENHI-PROJECT-24681047
[Journal Article] Discovery of macrocyclic peptides armed with a mechanism-based warhead that isoform-selectively inhibit a human deacetylase SIRT22012
- Author(s)
  Morimoto, J.: Hayashi, Y., Suga, H.
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: (In press) Pages: 3423-3427
- DOI
  10.1002/anie.201108118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal Synthesis of Backbone-Macrocyclic Peptides Containing γ-Amino Acids2011
- Author(s)
  Y.Ohshiro, E.Nakajima, Y.Goto, S.Fuse, T.Takahashi, T.Doi, H.Suga
- Journal Title
  
  ChemBioChem
  
  Volume: 12 Pages: 1183-1187
- DOI
  10.1002/cbic.201100104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22750145
[Journal Article] ペプチド医薬品開発の新基盤技術『RaPIDシステム』2011
- Author(s)
  下舞大・後藤佑樹・菅裕明
- Journal Title
  
  化学工業
  
  Volume: 62 Pages: 109-115
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum2011
- Author(s)
  K.Ojemalm, T.Higuchi, Y.Jiang, U.Langel, I.Nilsson, S.H.White, H.Suga*, G.von Heijne
- Journal Title
  
  Pro.Nat.Acad.Sci.
  
  Volume: 108(31)
- DOI
  10.1073/pnas.1100120108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Flexizymes : Their evolutionary history and the origin of catalytic function2011
- Author(s)
  Morimoto, J.; Hayashi, Y.; K.Iwasaki, K.; Suga, H.
- Journal Title
  
  Accounts of Chemical Research
  
  Volume: 44 Pages: 1359-1368
- DOI
  10.1021/ar2000953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
[Journal Article] Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library2011
- Author(s)
  Y.Yamagishi, I.Shoji, S.Miyagawa, T.Kawakami, T.Katoh, Y.Goto, H.Suga*
- Journal Title
  
  Chem Biol.
  
  Volume: 18 Pages: 1562-1570
- DOI
  10.1016/j.chembiol.2011.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase2011
- Author(s)
  J.Chung, E.Goo, S.Yu, O.Choi, J.Lee, J.Kim, H.Kim, J.Igarashi, H.Suga
- Journal Title
  
  Pro.Nat.Acad.Sci.
  
  Volume: 108(29) Pages: 12089-12094
- DOI
  10.1073/pnas.1103165108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Flexizymes for genetic code reprogramming2011
- Author(s)
  Y.Goto, T.Katoh, H.Suga
- Journal Title
  
  Nat Protoc.
  
  Volume: 6 Pages: 779-790
- DOI
  10.1038/nprot.2011.331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Ribosomal synthesis of backbone macrocyclic peptides2011
- Author(s)
  T.Katoh, Y.Goto, S.Raza, H.Suga*
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Pages: 9946-9958
- DOI
  10.1039/c1cc12647d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
[Journal Article] Synthesis of a backbone-cyclic peptide SFTI-1 promoted by the induced peptidyl-tRNA drop-off2011
- Author(s)
  T.-J.Kang, Y.Hayashi, H.Suga
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 50 Pages: 2159-2161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Engineering of the redox ribozyme for the determination of its architechure.2010
- Author(s)
  S.B.Pattnaik, K.Jin, K.Futai, H.Suga
- Journal Title
  
  Chemistry Letters
  
  Volume: 39 Pages: 786-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] RaPIDシステムによる特殊ペプチド薬剤の探索2010
- Author(s)
  飯田健夫・菅裕明
- Journal Title
  
  フロンティア22:生命現象を理解する分子ツール
  
  Pages: 71-76
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] RaPIDシステムが拓く新創薬戦略2010
- Author(s)
  後藤佑樹、伊東利紗、菅裕明
- Journal Title
  
  MEDCHEM NEWS
  
  Volume: 4 Pages: 26-31
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] 特殊環状ペプチドの翻訳合成と医薬品探索への展開2010
- Author(s)
  林剛介・大城幸紀・菅裕明
- Journal Title
  
  生化学
  
  Volume: 6 Pages: 505-514
- NAID
  10026899979
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] 擬天然物特殊ペプチドのプログラム翻訳合成と応用2010
- Author(s)
  菅裕明・樋口岳
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 68 Pages: 217-227
- NAID
  10026868150
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosome evolution for two artificial amino acids in E.coli2010
- Author(s)
  G.Hayashi, Y.Goto, H.Suga
- Journal Title
  
  Chemistry&Biology
  
  Volume: 17 Pages: 320-321
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal synthesis of dehydrobutyrineand methyllanthionine-containing peptides2009
- Author(s)
  Y. Goto, K. Iwasaki, K. Torikai, H. Murakami, H. Suga
- Journal Title
  
  Chemical Communication (in press)
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A flexizyme that selectively charges ameno activated with a water-friendly leaving group2009
- Author(s)
  N. Niwa, Y. Yamagishi, H. Murakami, H. Suga
- Journal Title
  
  Bioorganic Medicinal Chemistry Letter (in press掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Bases in the anticodon loop of tRNA(GGC)(Ala)prevent misreading2009
- Author(s)
  H.Murakami, A.Ohta, H.Suga
- Journal Title
  
  Nature Structural & Molecular Biology 16
  
  Pages: 353-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides2009
- Author(s)
  Y.Goto, K.Iwasaki, K.Torikai, H.Murakami, H.Suga
- Journal Title
  
  Chemical Communication
  
  Pages: 3419-3421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Diverse backbone-cyclized peptides via codon reprogramming2009
- Author(s)
  T.Kawakami, A.Ohta, M.Ohuchi, H.Ashigai, H.Murakami, H.Suga
- Journal Title
  
  Nature Chemical Biology 5
  
  Pages: 888-890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Translation initiation with initiator tRNA charged with exotic peptides2009
- Author(s)
  Y. Goto, H. Suga
- Journal Title
  
  Journal of American Chemical Society 131
  
  Pages: 5040-5041
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A flexizyme that selectively charges amino acids activated by a water-ffriendly leaving group2009
- Author(s)
  N.Niwa, Y.Yamagishi, H.Murakami, H.Suga
- Journal Title
  
  Bioorganic Medicinal Chemistry Letter 19
  
  Pages: 3892-3894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21241051
[Journal Article] Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides2009
- Author(s)
  Y.Goto, K.Iwasaki, K.Torikai, H.Murakami, H.Suga
- Journal Title
  
  Chemical Communication
  
  Pages: 1469-1472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21241051
[Journal Article] Translation initiation with initiator tRNA charged with exotic peptides2009
- Author(s)
  Y.Goto, H.Suga
- Journal Title
  
  Journal of the American Chemical Society 131
  
  Pages: 5040-5041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction2009
- Author(s)
  Y.Yamagishi, H.Ashigai, Y.Goto, H.Murakami, H.Suga
- Journal Title
  
  ChemBioChem 10
  
  Pages: 1469-1472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21241051
[Journal Article] Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction2009
- Author(s)
  Y.Yamagishi, H.Ashigai, Y.Goto, H.Murakami, H.Suga
- Journal Title
  
  ChemBioChem 10
  
  Pages: 1469-1472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides2009
- Author(s)
  E.Nakajima, Y.Goto, Y.Sako, H.Murakami, H.Suga
- Journal Title
  
  ChemBioChem 10
  
  Pages: 1186-1192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Ribosomal Synthesis of Peptides with C-Terminal Lactams, Thiolactones, and Alkylamides2009
- Author(s)
  E. Nakajima, Y. Goto, Y. Sako, H. Murakami and H. Suga
- Journal Title
  
  ChemBioChem (in press掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of dehydrobutyrine-and methyllanthinonine-containing2009
- Author(s)
  Y. Goto, H. Suga
- Journal Title
  
  Chemical Communication (in press掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A flexizyme that selectively charges amino acids activated with awater-friendly leaving group2009
- Author(s)
  N. Niwa, Y. Yamagishi, H. Murakami, H. Suga
- Journal Title
  
  Bioorganic Medicinal Chemistry Letter (in press)
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A flexizyme that selectively charges amino acids activated by a water-friendly leaving group2009
- Author(s)
  N.Niwa, Y.Yamagishi, H.Murakami, H.Suga
- Journal Title
  
  Bioorganic Medicinal Chemistry Letter 19
  
  Pages: 3892-3894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000005
[Journal Article] Bases in the anticodons loop of tRNA^<Ala> GGC prevent misreading2009
- Author(s)
  H. Murakami, A. Ohta, H. Suga
- Journal Title
  
  Nature Structural & Molecular Biology 16
  
  Pages: 353-358
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Bases in the anticodons loop of tRNAAlaGGC prevent misreading2009
- Author(s)
  H. Murakami, A.Ohta, H.Suga
- Journal Title
  
  Nature Structural &Molecular Biology 16
  
  Pages: 353-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of peptidase-resistant peptides closed by a non-reducible inter-sidechain bond2008
- Author(s)
  Y. Sako, Y. Goto, H. Murakami, H. Suga
- Journal Title
  
  ACS Chemical Biology 3
  
  Pages: 241-249
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of peptidase-resistant peptides closed by a non-reducible inter-sidechain bond2008
- Author(s)
  Y. Sako, Y. Goto, H. Murakami, H. Suga
- Journal Title
  
  ACS Chemical Biology 44(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of bicyclic peptides with two orthogomal inter-sidechain2008
- Author(s)
  Y. Sako, J Morimoto, H. Murakami, H. Suga
- Journal Title
  
  Journal of American Chemical Society 130
  
  Pages: 7932-7934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Strcutural basis of specific tRNA aminoacylattion by a small in vitro selected ribozyme2008
- Author(s)
  H. Xiao, H. Murakami, H. Suga, A. R. Ferre-D'Amare
- Journal Title
  
  Nature 454
  
  Pages: 358-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Exploration of incorporation of Nalpha-methylated amino acids into peptides by sense-suppression method2008
- Author(s)
  T. Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 361-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Initiating translation with D-amino acids2008
- Author(s)
  Y. Goto, H. Murakami, H. Suga
- Journal Title
  
  RNA 14
  
  Pages: 1399-1410
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Messenger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008
- Author(s)
  T. Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Chemistry & Biology 15
  
  Pages: 32-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of bicyclicpeptides with two orthogonalinter-sidechain reactions2008
- Author(s)
  Y. Sako, J. Morimoto, H. Murakami, H. Suga
- Journal Title
  
  Journal of American Chemical Society 130
  
  Pages: 7932-7934
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Reprogramming the initiation event in translation for the synthesis of physiologically stablecyclic peptides2008
- Author(s)
  Y. Goto, A. Ohta, Y. Sako, Y. Yamagishi, H. Murakami, H. Suga
- Journal Title
  
  ACS Chemical Biology 4
  
  Pages: 120-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Polymerization of α-hydroxy acids by ribosomes2008
- Author(s)
  A. Ohta, H. Murakami, H. Suga
- Journal Title
  
  ChemBioChem (in press)
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Expression of histone H3 tailswith combinatorial lysinemodifications under thereprogrammed genetic code for theinvestigation on epigenetic markers2008
- Author(s)
  T.-J. Kang, S. Yuzawa, H. Suga
- Journal Title
  
  Chemistry &Biology 15
  
  Pages: 1166-1174
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers2008
- Author(s)
  T. J. Kang, S. Yuzawa, H. Suga
- Journal Title
  
  Chemistry & Bioloty 15
  
  Pages: 1166-1174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Messenger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008
- Author(s)
  T. Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Chemistry &Biology 15
  
  Pages: 32-42
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Polymerization of a-hydroxy acids by ribosomes2008
- Author(s)
  A. Ohta, H. Murakami, H. Suga
- Journal Title
  
  ChemBioChem 9
  
  Pages: 2773-2778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Synthesis of biopolymers using genetic code reprogramming2008
- Author(s)
  A. Ohta, Y. Yamagishi, H. Suga
- Journal Title
  
  Current Opinion in Chemical Biology 12
  
  Pages: 159-167
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of nonstandard peptides2008
- Author(s)
  T.-J. Kang, H. Suga
- Journal Title
  
  Biochemistry and Cell Biology 86
  
  Pages: 92-99
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Messeriger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008
- Author(s)
  T. Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Chemistty and Biology 14
  
  Pages: 32-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesisi of polypeptoids and peptoid-peptide hybrids2008
- Author(s)
  T.Kawakami, H.Murakami, H.Suga
- Journal Title
  
  Journal of American Chemical Society 130
  
  Pages: 16861-16863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Reprogramming the initiation event in translation for the synthesis of physiologically stable cyclic peptides2008
- Author(s)
  Y.Goto, A. Ohta, Y. Sako, Y. Yamagishi, H.Murakami, H. Suga
- Journal Title
  
  ACS Chemical Biology 3
  
  Pages: 120-129
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Symthesis of biopolymers using genetic code reprogramming2008
- Author(s)
  A. Ohta, Y. Yamagishi, H. Suga
- Journal Title
  
  Current Opinion in Chemical Biology 12
  
  Pages: 159-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of polypeptoids and peptoid-peptide hybrids2008
- Author(s)
  T.Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Journal of American Chemical Society 130
  
  Pages: 16861-16863
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Strcutural basis of specific tRNAaminoacylation by a small in vitroselected ribozyme2008
- Author(s)
  H. Xiao, H. Murakami, H. Suga
- Journal Title
  
  A. R. Ferre-D'Amare Nature 454
  
  Pages: 358-361
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of nonstandard peptides2008
- Author(s)
  T. J. Kang, H. Suga
- Journal Title
  
  Biochemistry and Cell Biology 86
  
  Pages: 92-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] In vitro selection of a 5'-purine ribonucleotide transferase ribozyme2007
- Author(s)
  Taek-Jin Kang, Hiroaki Suga
- Journal Title
  
  Nucleic Acid Research (In press)
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Re-engineering an in-vitro evolved ribozyme2007
- Author(s)
  S. Pattnaik, H. Suga
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 381-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] The flexizyme system:A highly flexible tRNA aminoacyation tool for thr translation apparatus2007
- Author(s)
  M. Ohuchi, H. Murakami, H. Suga
- Journal Title
  
  Current Opinion in Chemistry and Biology 11
  
  Pages: 134-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 遺伝暗号リプログラミングによるポリエステルの翻訳合成2007
- Author(s)
  太田淳, 村上裕, 菅裕明
- Journal Title
  
  高分子 56・4月号
  
  Pages: 196-199
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Synthesis of polyester by means of genetic code reprogramming2007
- Author(s)
  A. Ohta, H. Murakami, E. Higashimura, H. Suga
- Journal Title
  
  Chemistry and Biology 13
  
  Pages: 1315-1322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 特殊ペプチドのコンビナトリアル翻訳合成2007
- Author(s)
  後藤佑樹, 太田淳, 村上裕, 菅裕明
- Journal Title
  
  化学工業 58・4月号
  
  Pages: 255-262
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 遺伝暗号のリプログラミング2007
- Author(s)
  佐古佑介・村上裕・菅裕明
- Journal Title
  
  蛋白質核酸酵素 52
  
  Pages: 1643-1648
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] In vitro selection of a 5'-purinenucleotide transferase ribozyme2007
- Author(s)
  T.-J. Kang, H. Suga
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 379-380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Exploration of ineorporation of Nalpha-methylated amino acids into peptides by sense-suppression method2007
- Author(s)
  T. Kawakami, H. Murakami, H. Suga
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 361-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] In situ generation of aminoacyl-tRNAs assisted by ribozymes in translation apparatus2007
- Author(s)
  M. Ohuchi, H. Murakami, H. Suga
- Journal Title
  
  Nucleic Acids Symposium Series 51
  
  Pages: 361-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] In vitro evolution of flexizymes that function under the conditions in translation system2006
- Author(s)
  Masaki Ohuchi, Hiroshi Murakami, Hiroaki Suga
- Journal Title
  
  Nucleic Acids Symposium Series 50
  
  Pages: 299-300
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Translation initiation by using various N-acylaminoacyl tRNAs2006
- Author(s)
  Yuki Goto, Hiroshi Ashigai, Yusuke Sako, Hiroshi Murakami, Hiroaki Suga
- Journal Title
  
  Nucleic Acids Symposium Series 50
  
  Pages: 293-294
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 合成生物学・その概念と未来2006
- Author(s)
  木賀大輔, 菅裕明
- Journal Title
  
  バイオニクス・オーム社 3月号
  
  Pages: 28-33
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Flexizyme as a versatile tRNA acylation catalyst and the application for translation2006
- Author(s)
  Hiroshi Murakami, Atsushi Ohta, Yuki Goto, Yusuke Sako, Hiroaki Suga
- Journal Title
  
  Nucleic Acids Symposium Series 50
  
  Pages: 35-36
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A highly flexible tRNA acylation system for nonnatural polypeptide synthesis2006
- Author(s)
  Hiroshi Murakami, Atsushi Ohta, Hiroshi Ashigai, Hiroaki Suga
- Journal Title
  
  Nature Methods in press
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of peptides having various acyl groups on the N-terminus2006
- Author(s)
  Yuki Goto, Hiroshi Ashigai, Yusuke Sako, Hiroshi Murakami, Hiroaki Suga
- Journal Title
  
  Peptide Science 43
  
  Pages: 46-47
- NAID
  10020528886
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A highly flexible tRNA acylation system for nonnatural polypeptide synthesis2006
- Author(s)
  Hiroshi Murakami, Atsushi Ohta, Hiroshi Ashigai, Hiroaki Suga
- Journal Title
  
  Nature Methods 3
  
  Pages: 357-359
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribosomal synthesis of non-natural peptide using the flexizyme system2006
- Author(s)
  Hiroshi Murakami, Atsushi Ohta, Yuki Goto, Yusuke Sako, Hiroaki Suga
- Journal Title
  
  Peptide Science 43
  
  Pages: 48-49
- NAID
  10020528891
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] A novel therapeutic approach for genetic diseases by introduction of suppressor tRNA2006
- Author(s)
  Yusuke Sako, Fusako Usuki, Hiroaki Suga
- Journal Title
  
  Nucleic Acids Symposium Series 50
  
  Pages: 239-240
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] フレキシザイムを用いた遺伝暗号の拡張とリプログラミング2006
- Author(s)
  村上裕, 菅裕明
- Journal Title
  
  蛋白質核酸酵素 51・16
  
  Pages: 28-33
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] セントラルドグマをつくりかえる2006
- Author(s)
  村上裕, 菅裕明, 平尾一郎
- Journal Title
  
  バイオニクス・オーム社 3月号
  
  Pages: 34-39
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 細胞内情報をあやつる2006
- Author(s)
  築地真也, 菅裕明, 長棟輝行
- Journal Title
  
  バイオニクス・オーム社 3月号
  
  Pages: 46-51
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] フレキシザイム-遺伝暗号の拡張とリプログラミングへの応用2006
- Author(s)
  村上裕, 菅裕明
- Journal Title
  
  バイオテクノロジージャーナル 6・11/12月号
  
  Pages: 2496-2501
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] 人工リボザイムでRNAワールドの検証に挑む2005
- Author(s)
  菅裕明
- Journal Title
  
  現代化学 6月号
  
  Pages: 44-50
- NAID
  40006766368
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Programmable ribozymes for misoharging tRNA with nonnatural amino acids and their applications to translation2005
- Author(s)
  Dimitrios Kourouklis, Hiroshi Murakami, Hiroaki Suga
- Journal Title
  
  Methods 36(3)
  
  Pages: 239-244
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Ribozymes that use redox cofactors2004
- Author(s)
  S.Tsukiji, K.Ramaswamy, H.Suga
- Journal Title
  
  Journal Pure and Applied Chemistry 76
  
  Pages: 1525-1536
- Data Source
  KAKENHI-PROJECT-16101007
[Journal Article] Reduction of an aldehyde by a NADH/Zn^<2+>-dependent redox active ribozyme2004
- Author(s)
  S.Tsukiji, S.Pattnaik, H.Suga
- Journal Title
  
  Journal of American Chemical Society 126
  
  Pages: 5044-5045
- Data Source
  KAKENHI-PROJECT-16101007
[Patent] Ｄ－アミノ酸及びβ－アミノ酸の取り込みを増強するｔＲＮＡのＤ及びＴアームの改変2018
- Inventor(s)
  菅　裕明,加藤　敬行
- Industrial Property Rights Holder
  菅　裕明,加藤　敬行
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-26220204
[Patent] 多種の非タンパク質性アミノ酸を利用できるカスタムメイドペプチド翻訳合成系2018
- Inventor(s)
  菅　裕明,加藤　敬行,岩根　由彦
- Industrial Property Rights Holder
  菅　裕明,加藤　敬行,岩根　由彦
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-26220204
[Patent] ペプチドライブラリーの製造方法2018
- Inventor(s)
  菅　裕明,後藤　佑樹,阿部　郁朗,岡田　正弘,井上　澄香
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PLANNED-16H06444
[Patent] 化合物ライブラリー及び化合物ライブラリーの製造方法2018
- Inventor(s)
  菅　裕明,後藤　佑樹,尾仲　宏康,ヴィノグラドフ　アレクサンダー
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PLANNED-16H06444
[Patent] C-Metタンパク質アゴニスト2013
- Inventor(s)
  菅裕明、伊藤健一郎
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2013-10-15
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] MATE活性阻害ペプチド2013
- Inventor(s)
  菅裕明、濡木理、クリストファージェイヒポライト、田中良樹
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2013-07-28
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] MATE 活性阻害ペプチド2013
- Inventor(s)
  菅裕明、濡木理、ヒポリトクリストファー、田中良樹
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2013-07-28
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法2013
- Inventor(s)
  菅裕明
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-08-26
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] c-Metタンパク質アゴニスト2013
- Inventor(s)
  菅裕明, 伊藤健一郎
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-15
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法2013
- Inventor(s)
  菅裕明
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2013-08-26
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] MATE活性阻害ペプチド2012
- Inventor(s)
  菅裕明、濡木理、クリストファーヒポリト、田中良樹
- Industrial Property Rights Holder
  菅裕明、濡木理、クリストファーヒポリト、田中良樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-170144
- Filing Date
  2012-07-31
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] アゾリン化合物及びアゾール化合物のライブラリー、並びにその製造方法2012
- Inventor(s)
  菅裕明・後藤佑樹・伊藤悠美
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2012-03-09
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] pH依存的に標的分子に結合するペプチドのスクリーニング方法2012
- Inventor(s)
  菅裕明、飯田健夫
- Industrial Property Rights Holder
  菅裕明、飯田健夫
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-129056
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] アゾリン化合物およびアゾール化合物のライブラリー、並びにその製造方法2011
- Inventor(s)
  菅裕明, 後藤佑樹, 伊藤悠美
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2010-190315
- Filing Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 安定化された二次構造を有するペプチド、及びペプチドライブラリー、それらの製造方法2011
- Inventor(s)
  菅裕明、樋口岳
- Industrial Property Rights Holder
  東京大学
- Acquisition Date
  2011-12-05
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 安定化された二次構造を有するペプチド、及びペプチドライブラリー、それらの製造方法2011
- Inventor(s)
  菅裕明、樋口岳
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 新規人工翻訳合成系2011
- Inventor(s)
  菅裕明・村上裕・後藤佑樹
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2011-08-26
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] ペプチドライブラリーの製造方法、ペプチドライブラリー、およびスクリーニング方法2011
- Inventor(s)
  菅裕明, 森本淳平
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2011-12-05
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 安定化された二次構造を有するペプチド、およびペプチドライブラリー、それらの製造方法2011
- Inventor(s)
  菅裕明, 樋口岳
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2011-12-05
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] N-メチルアミノ酸おびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法2011
- Inventor(s)
  菅裕明, 山岸祐介
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2011-09-08
- Overseas
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 新規人工翻訳合成系2010
- Inventor(s)
  菅裕明・村上裕・後藤佑樹
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2010-190315
- Filing Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] N・メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法2010
- Inventor(s)
  菅裕明, 山岸祐介
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2010-202012
- Filing Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] αヘリックス2次元構造を固定した特殊ペプチド化合物ライブラリーの合成法と活性種探索法2010
- Inventor(s)
  菅裕明, 樋口岳
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2010-270958
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 特異的機能低分子化合物含有特殊ペプチドのライブラリーの合成法と活性種探索法2010
- Inventor(s)
  菅裕明, 森本淳平
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2010-270507
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21000005
[Patent] 環状化学物ペプチドの合成法2007
- Inventor(s)
  菅裕明, 村上裕, 後藤佑樹, 山岸祐介, 足海洋史, 佐古佑介
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2007-080141
- Filing Date
  2007-03-26
- Data Source
  KAKENHI-PROJECT-16101007
[Patent] N末端に非天然骨格を持つポリペプチドの翻訳合成とその応用2006
- Inventor(s)
  菅裕明, 村上裕, 後藤佑樹, 太田淳
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2006-312000
- Filing Date
  2006-11-17
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] Displayable Pseudo-Natural Peptides and Products2021
- Author(s)
  Hiroaki Suga
- Organizer
  The 18th Akabori Conference
- Invited
- Data Source
  KAKENHI-PROJECT-20H05618
[Presentation] The next generation of RaPID display2020
- Author(s)
  Hiroaki Suga
- Organizer
  RSC Desktop Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Presentation] Displayable Pseudo-Natural Products2020
- Author(s)
  Hiroaki Suga
- Organizer
  Gordon Research Conferences: Advancing Peptides as Tools, Materials and Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery processes of macrocyclic peptide therapeutics: A show case of anti-PlexinB1 peptides2020
- Author(s)
  Hiroaki Suga
- Organizer
  14th International Conference on Protein Phosphatase Japan Bone Academy 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Presentation] The power of RaPID system for de novo macrocycles discovery2020
- Author(s)
  Hiroaki Suga
- Organizer
  Target 2035 A prove for every protein Kick-off webinar series Asia/Pacific session
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Presentation] From Basic Science to Innovation -From genetic code reprogramming to peptide therapeutics2020
- Author(s)
  Hiroaki Suga
- Organizer
  MIRAI 2.0 Japanese-Swedish Joint Kick-off/Scientific Webinar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05618
[Presentation] From constrained peptides to neobiologics2020
- Author(s)
  Hiroaki Suga
- Organizer
  AsiaTIDES: Oligonucleotide & Peptide Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] From Constrained Peptides to NeoBiologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  The 8thChemical Protein Synthesis (CPS) Meeting 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery process of peptide drug leads by the RaPID system2019
- Author(s)
  Hiroaki Suga
- Organizer
  26th International smposium: Synthesis in organic chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] The RaPID way to devise biologically active peptides and biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  20th Tetrahedron Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Macrocyclic pseudo-natural peptides for anti-cancer therapies2019
- Author(s)
  H Suga
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Rvolutionizing the discovery processes of de novo bioactive peptidesand biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Unnatural Amino Acids for Exotic Macrocyclic Peptides and Targeting IL6R as a Case Study2019
- Author(s)
  Hiroaki Suga
- Organizer
  Drug Discovery Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery processes of therapeutically valuable peptides and biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  47th IUPAC Chemistry Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery process of macrocyclic peptides for therapeutic use2019
- Author(s)
  Hiroaki Suga
- Organizer
  21st GFPP Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Peptide therapeutics innovation2019
- Author(s)
  Hiroaki Suga
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Assocation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery processes of de novo bioactive peptides and biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  Bohlmann Lecture Freie University Berlin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] De novo discovery of bioactive pseudo-natural peptides from biosynthetic libraries2019
- Author(s)
  Hiroaki Suga
- Organizer
  30th Anniversary Today-Unistra Symposium on Complexity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] In vitro pseudo-natural product biosynthesis and selection2019
- Author(s)
  Hiroaki Suga
- Organizer
  14th International Symposium on the Genetics of Industrial Microorganisms (GIM) 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery processes of de novo bioactive peptides and neobiologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  34th William S. Johnson Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] From constrained peptides to biologics2019
- Author(s)
  H Suga
- Organizer
  The Festival of Biologics San Diego
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery process de novo bioactive peptides and biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  5th Peptides & Proteins Symposium Singapre
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the Discovery Processes of de novo Bioactive Peptides and Biologics2019
- Author(s)
  Hiroaki Suga
- Organizer
  26th American Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Worldwide Perspectives on SynCell2019
- Author(s)
  Hiroaki Suga
- Organizer
  SynCell2019: Defining the Challenges
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] 擬天然ペプチドのリボソーム型生体外発現に関する最近の研究成果2019
- Author(s)
  H Suga
- Organizer
  AsiaTIDES: Oligonucleotide & Peptide Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery process of bioactive peptides2019
- Author(s)
  Hiroaki Suga
- Organizer
  RU Lemieux Lecture on Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] The RaPID way to discover bioactive pseudo-natural macrocycles2018
- Author(s)
  H Suga
- Organizer
  10th International Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] "The RaPID way to discover bioactive pseudo-natural peptides with macrocyclic scaffold"2018
- Author(s)
  H Suga
- Organizer
  The Protein Society Annual Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID way to discover bioactive pseudo-natural macrocycles2018
- Author(s)
  H Suga
- Organizer
  10th International Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Revolutionizing the discovery process of bioactive peptides2018
- Author(s)
  H Suga
- Organizer
  Basel Life 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID System That Has Revolutionized the Discovery Process of Peptide Therapeutics2018
- Author(s)
  H Suga
- Organizer
  ACS Publications Symposium: Innovation at the Frontier of Chemistry and Life Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] The RaPID discovery of bioactive pseudo-natural peptides2018
- Author(s)
  H Suga
- Organizer
  CHI's 13th Annual Drug Discovery Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID Discovery of Bioactive Pseudo-Natural Peptides2018
- Author(s)
  H Suga
- Organizer
  1st Japanese-German Symposium Biosynthesis and Function of Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] 擬天然ペプチドのリボソーム型生体外発現に関する最近の研究成果2018
- Author(s)
  H Suga
- Organizer
  AsiaTIDES: Oligonucleotide & Peptide Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Revolutionizing the discovery process of peptide drug leads2018
- Author(s)
  H Suga
- Organizer
  Nature Conference on Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] The RaPID discovery of bioactive pseudo-natural peptides2018
- Author(s)
  H Suga
- Organizer
  CHI's 13th Annual Drug Discovery Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] From constrained peptides to biologics2018
- Author(s)
  H Suga
- Organizer
  The Festival of Biologics San Diego
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID System That Has Revolutionized the Discovery Process of Peptide Therapeutics2018
- Author(s)
  H Suga
- Organizer
  ACS Publications Symposium: Innovation at the Frontier of Chemistry and Life Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Revolutionizing the discovery process of bioactive peptides2018
- Author(s)
  H Suga
- Organizer
  Basel Life 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Revolutionizing the discovery process of peptide drug leads2018
- Author(s)
  H Suga
- Organizer
  Nature Conference on Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID way to discover bioactive pseudo-natural peptides with macrocyclic scaffold2018
- Author(s)
  H Suga
- Organizer
  The Protein Society Annual Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] The RaPID Discovery of Bioactive Pseudo-Natural Peptides2018
- Author(s)
  H Suga
- Organizer
  1st Japanese-German Symposium Biosynthesis and Function of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID way to discover bioactive macrocyclic peptides expressed under the reprogrammed genetic code2018
- Author(s)
  H Suga
- Organizer
  2018 Genetic Code Espansion Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Macrocyclic pseudo-natural peptides for anti-cancer therapies2018
- Author(s)
  H Suga
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID way to discover bioactive macrocyclic peptides expressed under the reprogrammed genetic code2018
- Author(s)
  H Suga
- Organizer
  2018 Genetic Code Espansion Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] One-Pot Synthesis and Screening of Pseudo-Natural Peptides and Products2017
- Author(s)
  H Suga
- Organizer
  The Bioorganic Chemistry Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Inorporation of nonproteinogenic amino acids into polypeptides from protein functional studies to drug discovery2017
- Author(s)
  H Suga
- Organizer
  The Ins-and-Outs of Membrane Biolog
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] One-Pot Synthesis and Screening of Pseudo-Natural Peptides and Products2017
- Author(s)
  Hiroaki Suga
- Organizer
  2017 Bioorganic Chemistry Gordon Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID discovery of bioactive pseudo-natural peptides2017
- Author(s)
  H Suga
- Organizer
  Nanoscience Days 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID way to discover pseudo-natural peptides and products2017
- Author(s)
  H Suga
- Organizer
  Benzon Symposium; New Paradigms of Protein Engineering & Applications in Modern Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID way to discover pseudo-natural peptides and products for therapeutic uses2017
- Author(s)
  H Suga
- Organizer
  14th Horizons in Molecular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID Way to Discover Pseudo-natural Peptides and Products for Therapeutic Uses2017
- Author(s)
  Hiroaki Suga
- Organizer
  Dutch peptide symposium 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID Discovery of Pseudo-Natural Peptides2017
- Author(s)
  H Suga
- Organizer
  25th American Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID Way to Discover Pseudo-natural Peptides and Products for Therapeutic Uses2017
- Author(s)
  H Suga
- Organizer
  Dutch Peptide Symposium 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] RaPID Way to Discover Pseudo-natural Peptides for Therapeutic Uses2017
- Author(s)
  Hiroaki Suga
- Organizer
  GDCh Scientific Forum Chemistry 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] RaPID Way to Discover Pseudo-natural Peptides for Therapeutic Uses2017
- Author(s)
  H Suga
- Organizer
  GDCh Scientific Forum Chemistry 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Translation-coupled in vitro reconstitution of pseudo-natural peptide biosynthesis2017
- Author(s)
  Hiroaki Suga
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover pseudo-natural peptides and products Discussion2017
- Author(s)
  Hiroaki Suga
- Organizer
  Benzon Symposium 63-New Paradigms of Protein Engineering-Applications in Modern Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive pseudo-natural peptides2017
- Author(s)
  H Suga
- Organizer
  26th French-Japanese Symposium on Medicinal & Fine Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Genetic code reprogramming assisted by flexizymes and pseudo-natural peptide discovery2017
- Author(s)
  Hiroaki Suga
- Organizer
  AARS2017 (2017 IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID Discovery of Pseudo-Natural Peptides2017
- Author(s)
  Hiroaki Suga
- Organizer
  25th American Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2017
- Author(s)
  H Suga
- Organizer
  11th International Symposium on Bioorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID Way to Discover Bioactive Pseudo-Natural Peptides2017
- Author(s)
  Hiroaki Suga
- Organizer
  Perspectives in Molecular Pharmacology 25 Years FMP
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID Way to Discover Bioactive Pseudo-Natural Peptides2017
- Author(s)
  H Suga
- Organizer
  Symposium and celebrations of the 25th anniversary of the Leibniz-Institut fur Molekulare Pharmakologie
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID Way to Discover Pseudo-natural Peptides2017
- Author(s)
  Hiroaki Suga
- Organizer
  7th Symposium on Advances in Synthetic and Medicinal
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive pseudo-natural peptides2017
- Author(s)
  Hiroaki Suga
- Organizer
  26th French-Japanese Symposium on Medicinal and Fine Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID Way to Discover Pseudo-natural Peptides2017
- Author(s)
  H Suga
- Organizer
  7th Symposium on Advances in Synthetic and Medicinal Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Genetic code reprogramming assisted by flexizymes and pseudo-natural peptide discovery2017
- Author(s)
  H Suga
- Organizer
  AARS2017 (2017 IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] Inorporation of nonproteinogenic amino acids into polypeptides from protein functional studies to drug discovery2017
- Author(s)
  Hiroaki Suga
- Organizer
  The Ins-and-Outs of Membrane Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Translation-coupled in vitro reconstitution of pseudo-natural peptide biosynthesis2017
- Author(s)
  H Suga
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Naural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06444
[Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2017
- Author(s)
  Hiroaki Suga
- Organizer
  11th International Symposium of Bioorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] The RaPID discovery of bioactive pseudo-natural peptides2017
- Author(s)
  Hiroaki Suga
- Organizer
  Nanoscience Days 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016
- Author(s)
  Hiroaki Suga
- Organizer
  International RNA meeting 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊環状ペプチドによる人工Metアゴニスト.2016
- Author(s)
  Miao Wenyu、酒井克也、小澤直也、伊藤健一郎、菅裕明、松本邦夫
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] In vitro synthetic biology of the ribosome and genetic code: From basic science to applied research2016
- Author(s)
  Hiroaki Suga
- Organizer
  Symposium on the Genetics of Industrial Microorganisms GIM2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016
- Author(s)
  Hiroaki Suga
- Organizer
  EMBO Conference-Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Nomtraditional peptides and pseudo-natural products2016
- Author(s)
  Hiroaki Suga
- Organizer
  The 8th Takeda Science Foundation International Symposium on PharmaSciences
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016
- Author(s)
  Hiroaki Suga
- Organizer
  Banyu-Fukuoka Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016
- Author(s)
  Hiroaki Suga
- Organizer
  EMBO Conference-Chemical Biology 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016
- Author(s)
  Hiroaki Suga
- Organizer
  Gold Medal Awardee Lecture, Max-Bergmann Conference 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover pseudo-natural products & peptides for therapeutic uses2016
- Author(s)
  Hiroaki Suga
- Organizer
  The 1st international PSL Chemical Biology Symposium 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Ribosomal synthesis of highly N- and O-methylated cyclic peptide libraries for selection of　protein-protein interaction inhibitors with “drug-like” characteristics.2015
- Author(s)
  菅　裕明
- Organizer
  The 11th Australian Peptide Conference
- Place of Presentation
  Peppers Salt Resort & Spa, Australia
- Year and Date
  2015-10-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊ペプチド創薬イノベーション2015
- Author(s)
  菅　裕明
- Organizer
  Joint International Symposium on TGF-beta and Cancer
- Place of Presentation
  筑波国際会議場、日本
- Year and Date
  2015-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊環状ペプチドによるMet/HGF受容体アゴニストの創製2015
- Author(s)
  松本邦夫、酒井克也、伊藤健一郎、菅裕明
- Organizer
  インターフェロン・サイトカイン学会
- Place of Presentation
  東京工業大学（東京都目黒区大岡山）
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 特殊環状ペプチドによる人工HGFの創製2015
- Author(s)
  松本邦夫、酒井克也、伊藤健一郎、菅裕明
- Organizer
  肝細胞研究会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] Rapid way for the discovery of macrocyclic peptide drug leads:RaPID way to discover PPI agonists and antagonists2015
- Author(s)
  菅　裕明
- Organizer
  The Innternational chemical congress of Pacific Basin Societies 2015
- Place of Presentation
  Hawaii Convention Center, Honolulu, Hawaii USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way for the discovery of pseud-natural products2015
- Author(s)
  菅　裕明
- Organizer
  36th National Organic Chemistry Congress
- Place of Presentation
  Alma Mater Studiorum University, Bologna, Italy
- Year and Date
  2015-09-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Pseudo-Natural Products and Peptides for Therapeutic Applications2015
- Author(s)
  菅　裕明
- Organizer
  High Throughput Chemistry & Chemical Biology(GordonResearch Conference)
- Place of Presentation
  Colby-Sawyer College, New London, NH USA
- Year and Date
  2015-06-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊ペプチド創薬イノベーション：創薬のゲームチェンジを目指して2015
- Author(s)
  菅　裕明
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市中央区島中町）、日本
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Drug-like non-canonical cyclic peptides selected from diverse libraries2015
- Author(s)
  菅　裕明
- Organizer
  The third edition of the International Conference on Circular Proteins（ICCP2015）
- Place of Presentation
  Moreton island, at the Tangalooma Resort, Australia
- Year and Date
  2015-11-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 環状ペプチドによる人工Met受容体アゴニストの創製2015
- Author(s)
  酒井克也、伊藤健一郎、菅裕明、松本邦夫
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] A RaPID way for the discovery of pseud-natural products and its innovation2015
- Author(s)
  菅　裕明
- Organizer
  Organic Chemistry Symposium(Royal Society of Chemistry Roadshow)
- Place of Presentation
  東京大学武田ホール（東京都文京区弥生）、日本
- Year and Date
  2015-06-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Pseudo-Natural Product Synthesis and Drug Applications2014
- Author(s)
  菅　裕明
- Organizer
  International Conference on Medicinal Chemistry 2014
- Place of Presentation
  Rouen's Law Faculty meeting room, Rouen, France
- Year and Date
  2014-07-01
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 擬天然物の新機能創出分子技術2014
- Author(s)
  Hiroaki Suga
- Organizer
  日本化学会第94春期年会「社会持続的発展のための分子技術」
- Place of Presentation
  名古屋大学東山キャンパス(名古屋市)
- Year and Date
  2014-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] A novel drug discovery platform technology fro "Nontraditional" molecules2014
- Author(s)
  菅　裕明
- Organizer
  Pre-COST meeting “Innovation”
- Place of Presentation
  Universita Degli Studi Firenze, Siena, Italy
- Year and Date
  2014-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊ペプチド創薬イノベーション2014
- Author(s)
  菅　裕明
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学　豊中キャンパス、日本
- Year and Date
  2014-06-11
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive macrocyclic peptides2014
- Author(s)
  菅　裕明
- Organizer
  Cold Spring Harbor Asia "Synthetic Biology"
- Place of Presentation
  Suzhou Dushu Lake Conference Center, Suzhou, China
- Year and Date
  2014-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊ペプチド創薬イノベーション2014
- Author(s)
  菅　裕明
- Organizer
  The Origin 2014
- Place of Presentation
  奈良県新公会堂、日本
- Year and Date
  2014-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2014
- Author(s)
  Hiroaki Suga
- Organizer
  AsiaTIDES, 2. Plenary Lecture
- Place of Presentation
  シェラトン都ホテル東京(東京都港区)
- Year and Date
  2014-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] A RaPID way to discover bioactive macrocyclic peptides2014
- Author(s)
  菅　裕明
- Organizer
  Asian Chemical Biology Symposium
- Place of Presentation
  Education Resource Centre, Singapore
- Year and Date
  2014-12-15
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2014
- Author(s)
  菅裕明
- Organizer
  AsiaTIDES, 2.Plenary Lecture
- Place of Presentation
  シェラトン都ホテル東京(東京都港区)(招待講演)
- Year and Date
  2014-02-25
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] In Vitro Biophynthesis and Discovery of Pseudo-nutural Products2014
- Author(s)
  菅　裕明
- Organizer
  Chemical Biology meets Drug Discovery meeting, Royal Society of Chemistry
- Place of Presentation
  Lilly Research Centre Erl Wood Manor, Surrey, UK
- Year and Date
  2014-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 特殊ペプチド創薬イノベーション2014
- Author(s)
  菅　裕明
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学大塚講堂、日本
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] A RaPID way to discover bioactive macrocyclic Scafforld and its Innovation2014
- Author(s)
  菅　裕明
- Organizer
  Joint symposium of the Institute of Convergent Technology at Seoul National University and the Research Center for Advanced Science and Technology at the University of Tokyo
- Place of Presentation
  Conference RoomI, AICT, Suwon, Korea
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] 擬天然物の新機能創出分子技術2014
- Author(s)
  菅裕明
- Organizer
  日本化学会第94春期年会「社会持続的発展のための分子技術」
- Place of Presentation
  名古屋大学東山キャンパス(名古屋市)(招待講演)
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] A RaPID way to discover bioactive macrocyclic peptides2014
- Author(s)
  菅　裕明
- Organizer
  Switzerland-Japan Chemical Biology Symposium
- Place of Presentation
  University of Bern, Switzerland
- Year and Date
  2014-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-26220204
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Basel Chemical Society Lectureship
- Place of Presentation
  Medicinal Chemistry Navartis Institute (Basel, Switzerland)(招待講演)
- Year and Date
  2013-10-24
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Current Strategy for Delopment of Biopharmaceuticals and Small Molecule Drugs
- Place of Presentation
  北海道大学(北海道札幌)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  American Peptide Symposium 2013
- Place of Presentation
  Hilton Waikoloa Village (Hawaii, USA)(招待講演)
- Year and Date
  2013-06-23
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  RIKEN-Max Planc Joint Symposium
- Place of Presentation
  理化学研究所和光研究所(埼玉県和光市)(招待講演)
- Year and Date
  2013-04-16
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Solvay Conference of "New Chemistry and New Opportunities from the Expanding Protein Universe"
- Place of Presentation
  International Solvay Institute (Brussels, Belgium)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  "Jokichi Takamine" 130 years of Glasgow-Japan Collaboration
- Place of Presentation
  University of Glasgow (Glasgow, UK)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  ACS National Meeting
- Place of Presentation
  Indiana Convention Center (Indianapolis, USA)
- Year and Date
  2013-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  "Jokichi Takamine" 130 years of Glasgow-Japan Collaboration
- Place of Presentation
  University of Glasgow (Glasgow, UK)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Symposium on Foldamers
- Place of Presentation
  Les Cordeliers Conference Centre(Paris, France)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  RIKEN-Max Planc Joint Symposium
- Place of Presentation
  理化学研究所和光研究所(埼玉県和光市)
- Year and Date
  2013-04-16
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  International Conference on Structural Genomics2013, Structural Life Science
- Place of Presentation
  京王プラザホテル(北海道札幌)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Gordon Research Conference, Bioorganic Chemistry
- Place of Presentation
  Proctor Academy (New Hampshire, USA)
- Year and Date
  2013-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] The non-traditional peptide therapeutics2013
- Author(s)
  菅　裕明
- Organizer
  Discovery Chemistry Congress
- Place of Presentation
  Munich, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  American Peptide Symposium 2013
- Place of Presentation
  Hilton Waikoloa Village (Hawaii, USA)
- Year and Date
  2013-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Keynote Lecture, Symposium on Chemoselective Reactions for the Synthesis and Application
- Place of Presentation
  Max Planc Institute (Dortmund, Germany)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Lilly Distinguished Lecturer at Colorado State University
- Place of Presentation
  Colorado State University (Fort Collins, US)
- Year and Date
  2013-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Gordon Research Conference, Bioorganic Chemistry
- Place of Presentation
  Proctor Academy (New Hampshire, USA)(招待講演)
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Basel Chemical Society Lectureship
- Place of Presentation
  Medicinal Chemistry Navartis Institute (Basel, Switzerland)
- Year and Date
  2013-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Biochemistry Seminar of University of Colorado, BioFrontier Institute
- Place of Presentation
  Univerity of Colorado (Boulder, USA)
- Year and Date
  2013-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Keynote Lecture Symposium on Chemoselective Reactions for the Synthesis and Application
- Place of Presentation
  Max Planc Institute (Dortmund, Germany)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  ACS National Meeting
- Place of Presentation
  Indiana Convention Center (Indianapolis, USA)(招待講演)
- Year and Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  International Conference on Structural Genomics 2013, Structural Life Science
- Place of Presentation
  京王プラザホテル(北海道札幌)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  RiboClub
- Place of Presentation
  Hotel Cheribourg (Quebec,Canada)(招待講演)
- Year and Date
  2013-09-22
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Lilly Distinguished Lecturer at Colorado State University
- Place of Presentation
  Colorado State University (Fort Collins, US)(招待講演)
- Year and Date
  2013-09-10
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Korean Peptide Protein Society Meeting
- Place of Presentation
  Seoul National University (Seoul, Korea)(招待講演)
- Year and Date
  2013-11-29
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Korean Peptide Protein Society Meeting
- Place of Presentation
  Seoul National University (Seoul, Korea)
- Year and Date
  2013-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  RiboClub
- Place of Presentation
  Hotel Cheribourg (Quebec, Canada)
- Year and Date
  2013-09-22
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Current Strategy for Development of Biopharmaceuticals and Small Molecule Drugs
- Place of Presentation
  北海道大学(北海道札幌)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Solvay Conference of "New Chemistry and New Opportunities from the Expanding Protein Universe"
- Place of Presentation
  International Solvay Institute (Brussels, Belgium)(招待講演)
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  Symposium on Foldamers
- Place of Presentation
  Les Cordeliers Conference Centre (Paris, France)
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  Biochemistry Seminar of University of Colorado BioFrontier Institute
- Place of Presentation
  Univerity of Colorado (Boulder, USA)(招待講演)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  菅裕明
- Organizer
  5th Gratama Workshop
- Place of Presentation
  東京工業大学大岡山キャンパス(東京都目黒区)(招待講演)
- Year and Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Discovery of natural product-like petides accerelated by RaPID system2013
- Author(s)
  Hiroaki Suga
- Organizer
  5th Gratama Workshop
- Place of Presentation
  東京工業大学大岡山キャンパス(東京都目黒区)
- Year and Date
  2013-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] The non-traditional peptide therapeutics2012
- Author(s)
  菅　裕明
- Organizer
  ICCP2012-International Conference on Circular Proteins
- Place of Presentation
  Heron island, Australia
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2012
- Author(s)
  菅裕明
- Organizer
  北海道大学GCQE国際会議
- Place of Presentation
  札幌(招待講演)
- Year and Date
  2012-02-22
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチドが起こす構造生命科学と創薬の飛躍2012
- Author(s)
  菅裕明
- Organizer
  学術会議公開シンポジウム「構造生命科学」
- Place of Presentation
  東京(招待講演)
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] RaPID Discovery of Natural Product-Like Peptides against Therapeutic Targets2012
- Author(s)
  菅　裕明
- Organizer
  Asia TIDES Oligonucleotide and Peptide Research, Technology and Product Development
- Place of Presentation
  Las Vegas, NV USA
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] The non-traditional peptide therapeutics2012
- Author(s)
  菅　裕明
- Organizer
  13th Tetrahedron Symposium
- Place of Presentation
  Taipei, Taiwan
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] RaPID system: A new discovery tool of natural product-like peptides from de novo libraries2012
- Author(s)
  菅　裕明
- Organizer
  3rd International Symposium on DNA-encoded chemical libraries
- Place of Presentation
  Zurich, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Flexizyme, FIT and RaPID: The enabling technologies for probes discovery2012
- Author(s)
  菅　裕明
- Organizer
  XXIV tRNA Conference
- Place of Presentation
  Olmue, Chile
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Non-Traditional Peptide Therapeutic Leads2012
- Author(s)
  菅　裕明
- Organizer
  Gordon Research Conference Medicinal Chemistry
- Place of Presentation
  Colby-Sawyer College New London, NH USA
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] The non-traditional peptide therapeutics2012
- Author(s)
  菅　裕明
- Organizer
  EFMC-ISMC 2012 22nd International Symposium on Medicinal Chemistry
- Place of Presentation
  Berlin, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] The non-traditional peptide therapeutics2012
- Author(s)
  菅　裕明
- Organizer
  13th FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Bangkok, Thailand
- Invited
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  The 11th Tetrahedron Symposium "Frontiers in Organic and Bioorganic Chemistry"
- Place of Presentation
  Sitges, Barcelona, Spain(招待講演)
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  European Protein Society Meeting
- Place of Presentation
  Stockholm, Sweden(招待講演)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  The 2011 International Symposium on Aminoacyl-tRNA synthetases
- Place of Presentation
  Snowbird, Salt Lake City, USA(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  5th International Symposium on Advancing the Chemical Sciences on Challenges in Chemical Biology
- Place of Presentation
  Manchester, UK(招待講演)
- Year and Date
  2011-07-27
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  PepTalk, Cambrige Health Institute
- Place of Presentation
  Boston, Massachusetts, USA(招待講演)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug leads2011
- Author(s)
  菅裕明
- Organizer
  22^<nd> Enzyme Mechanisms Conference
- Place of Presentation
  St.Pete beach FL, USA
- Year and Date
  2011-01-04
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide, drug leads2011
- Author(s)
  菅裕明
- Organizer
  Royal Society discussion meeting : Chemical Origins and Early Evolution
- Place of Presentation
  London, UK
- Year and Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  The 9th Australian Peptide Conference
- Place of Presentation
  Hamilton Island, Australia(招待講演)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  細胞を創る会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  The 22nd American Peptide Symposium
- Place of Presentation
  San Diego, USA(招待講演)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  AsiaTIDES : Oligonucleotide and Peptide Research, Technology and Product Development
- Place of Presentation
  Tokyo, Japan(招待講演)
- Year and Date
  2011-02-28
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  日本分子生物学会年会「Leading Edge seminar」
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  International RNA Society Meeting
- Place of Presentation
  Kyoto, Japan(招待講演)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  The 38th International Symposium of Nucleic Acid Chemistry
- Place of Presentation
  Sapporo, Hokkaido, Japan(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011
- Author(s)
  菅裕明
- Organizer
  名古屋大学GCOE国際会議
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2010
- Author(s)
  菅裕明
- Organizer
  日本生物物理学会年会
- Place of Presentation
  仙台、東北大学
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010
- Author(s)
  菅裕明
- Organizer
  RIKEN Chemical Biology Symposium
- Place of Presentation
  和光、理研和光研究所
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2010
- Author(s)
  菅裕明
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都、京都テレサホール
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010
- Author(s)
  菅裕明
- Organizer
  The 75^<th> Israel Chemical Society Meeting, Israel
- Place of Presentation
  Tel Aviv, Israel
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2010
- Author(s)
  菅裕明
- Organizer
  仙台万有シンポジウム
- Place of Presentation
  仙台、仙台国際センター
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010
- Author(s)
  菅裕明
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  京都、京都国際コンファレンスセンター
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010
- Author(s)
  菅裕明
- Organizer
  The 2010 Annual Meeting of the American Society for Biochemistry and Molecular Biology
- Place of Presentation
  Los Angels, California, USA
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010
- Author(s)
  菅裕明
- Organizer
  AsiaTide
- Place of Presentation
  東京
- Year and Date
  2010-02-23
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2010
- Author(s)
  菅裕明
- Organizer
  日本RNA学会年会
- Place of Presentation
  東京、一橋記念講堂
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010
- Author(s)
  菅裕明
- Organizer
  2010 Chemistry & Biology of Peptides Gordon Research Conference
- Place of Presentation
  Ventura, USA
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2010
- Author(s)
  菅裕明
- Organizer
  日本化学会年会、ATPプログラム
- Place of Presentation
  大阪
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug leads2010
- Author(s)
  菅裕明
- Organizer
  PacifiChem 2010
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010
- Author(s)
  菅裕明
- Organizer
  Yale University, Symposium of Chemical Biology
- Place of Presentation
  Connecticut, USA
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010
- Author(s)
  菅裕明
- Organizer
  国際構造エピゲノムシンポジウム
- Place of Presentation
  横浜、理研横浜研究所
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  The 1^<st> International Conference for Circular Protein
- Place of Presentation
  Heron Island, Australia
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  The 3rd Asia-Pacific International Peptide Symposium
- Place of Presentation
  Jeju Island, Korea
- Year and Date
  2009-11-09
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  Naito Foundation Conference in Chemical Biology
- Place of Presentation
  札幌
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチドの翻訳合成:創薬への展開2009
- Author(s)
  菅裕明
- Organizer
  日本化学会
- Place of Presentation
  西船橋・日大キャンパス
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] ETH Zurich2009
- Author(s)
  菅
- Organizer
  Institute of Organic Chemistry Seminar
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2009-01-08
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] 第2次先端ウオッチング-生合成化学2009
- Author(s)
  菅
- Organizer
  日本化学会年会
- Place of Presentation
  西船橋
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  Burugenstock Conference
- Place of Presentation
  Lucerne, Switzerland
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic code reprogramming : A new emerging technology for the discovery of non-standard peptidic drugs2009
- Author(s)
  菅裕明
- Organizer
  Burgenstock Conference
- Place of Presentation
  Lucerne, Switzerland
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21241051
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  Peptide Engineering : Therapeutic Peptide" Fifth Peptide Engineering Meeting
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  第5回日韓天然物化学談話会
- Place of Presentation
  湯河原
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] 特殊ペプチド創薬2009
- Author(s)
  菅裕明
- Organizer
  日本発生学会年会
- Place of Presentation
  三島
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009
- Author(s)
  菅裕明
- Organizer
  Nottingham 'New Horizons' meeting 2009
- Place of Presentation
  Nottingham, UK
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21000005
[Presentation] International Symposium on Molecular Recognition of DNA2008
- Author(s)
  菅
- Organizer
  Biological Applications
- Place of Presentation
  東京
- Year and Date
  2008-09-16
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] 特殊ペプチドの翻訳合成:創薬への展開2008
- Author(s)
  菅裕明
- Organizer
  日本ケミカルバイオロジー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] of Methods in Protein Structural Analysis2008
- Author(s)
  菅
- Organizer
  The 17th Meeting
- Place of Presentation
  札幌
- Year and Date
  2008-08-28
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] Chemical Biology of non-standard peptides2008
- Author(s)
  菅裕明
- Organizer
  RIKEN Conference in Chemical Biology
- Place of Presentation
  成田
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  第7回新規素材探索研究会セミナー
- Place of Presentation
  横浜
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  日本ケミカルバイオロジー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  前期有機合成化学講習会
- Place of Presentation
  東京
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  第128回日本薬学会年会・特別講演
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  BioJapan
- Place of Presentation
  横浜
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] Veyrier du Lac2008
- Author(s)
  菅
- Organizer
  Aminoacyl-tRNA Synthetase Meeting 2008
- Place of Presentation
  France
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] Japanese-German Frontier of Science2008
- Author(s)
  菅
- Organizer
  Heidelberg
- Place of Presentation
  Germany
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] RIKEN Conference2008
- Author(s)
  菅
- Organizer
  Chemical Biology
- Place of Presentation
  成田
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation]2008
- Author(s)
  菅
- Organizer
  第56回日本化学療法学会総会
- Place of Presentation
  岡山
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-16101007
[Presentation] ‘Discovering protease inhibitors: Using genetic code reprogramming to generate macrocyclic peptides’
- Author(s)
  Joseph Rogers, Ikou Shoji, Hiroaki Suga
- Organizer
  Lorne conference on protein structure and function
- Place of Presentation
  Lorne, Australia
- Year and Date
  2015-02-08 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-13F03766
[Presentation] 亜型を超えた感染阻害活性を示すヘマグルチニン結合性特殊環状ペプチド
- Author(s)
  斉藤　誠、安井文彦、棟方　翼、飛田良美、小澤　真、小原恭子、伊東利紗、菅　裕明、佐々木　亨、窪田規一、小原道法
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25670224

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Suga Hiroaki 菅 裕明

SUGA Hiroaki 菅 裕明

Research Projects

Research Products

Co-Researchers

特殊ペプチド・擬天然物創薬の命題への挑戦Principal Investigator

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ペプチドセレクションによる酵素ミミック創薬のための戦略Host Researcher

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Synthetic biology of pseudo-natural products by artificial in vitro biosynthesisPrincipal Investigator

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チアゾール含有環状ペプチドの翻訳合成法Host Researcher

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中性子捕捉療法を指向したホウ素含有環状ペプチドの開発Host Researcher

Host Researcher

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抗菌作用を発揮する大環状特殊ペプチドの発見と開発Host Researcher

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薬剤活性向上した大環状ペプチドを開発する新規戦略Host Researcher

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プロリル－４－ヒドロキシダーゼをアイソフォーム選択的に阻害する大環状化合物の発見Host Researcher

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Generation of minimal peptide catalysts based on the macrocyclic scaffoldPrincipal Investigator

Principal Investigator

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Principal Investigator

Suga Hiroaki 菅裕明

SUGA Hiroaki 菅裕明