KOGA Tomohiro 古賀智裕

… Alternative Names

古賀智裕コガトモヒロ

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Researcher Number	90537284
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 病院(医学系), 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 長崎大学, 病院(医学系), 講師 2016 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2014 – 2015: 長崎大学, 病院(医学系), 助教 2013: 長崎大学, 病院第一内科, 助教 2011: Nagasaki University, 大学病院, その他 2010: 長崎大学, 病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 家族性地中海熱 / 血清バイオマーカー / 関節リウマチ / 免疫老化 / MEFV遺伝子 / 全ゲノム解析 / バイオマーカー / トランスレーショナルリサーチ / 免疫学 / ゲノム … More / 前エクソン解析 / 成人スチル病 / 全エクソン解析 / IL-18 / IL-1β / 成人発症スチル病 / 関節炎誘導マウス / CaMK4 / シトルリン化 / RNAレギュロン … More Except Principal Investigator インフラマソーム / 関節リウマチ / ヒトタンパク質アレイ / 自己炎症疾患 / サイトカイン / IL-1β / IL-18 / イムノフェノタイピング / ACPA / 骨破壊 / 破骨細胞 / 単球 / バイオマーカー / 全身性エリテマトーデス / 疾患インタラクトーム / タンパク質アレイ / 疾患インララクトーム / 家族性地中海熱 / PPF / 間質性肺疾患 / 多発性筋炎/皮膚筋炎 / inflammasome / autoinflammation / ASD / M2BPGi / Gal-3 / カスパーゼ1 / 成人スチル病 / シングルセルRNAシーケンス / プロテオミクス / シングルセルRNAシーケンス（scRNAseq） / TAFRO / iMCD-IPL / iMCD-NOS / iMCD-TAFRO / 24k-HUPA / 周期熱症候群 / 亜型解析 / 遺伝学的解析 / 疾患レジストリ / 難病プラットフォーム / 疾患活動性指標 / GWAS / クラスター解析 / ゲノム解析 / レジストリ / 予後不良病型 / 疾患活動性 / レジストリ研究 / ベーチェット病 / 自己炎症 / IL-IB / パイソン / 自然免疫 / C5a / 補体 / パイリン / 成人発症スチル病 / Caspase-1 / 治療反応スコア / 関節画像 / 精密医療 / コラーゲン誘発関節炎 / 滑膜炎 / 関節画像評価 / マイクロアレイ / 臨床 / 免疫学 / T細胞 / CD52 / 関節超音波 / アレイ解析 / リバースシグナル / CTLA-4Ig / ACPA-サブクラス / 滑膜線維芽細胞 / サイトカイン・ケモカイン / M1・M2 / CTLA-4-Ig / 関節軟骨 / 関節裂隙狭小化 / MRI / 軟骨傷害 / 国際情報交換、アメリカ / CD86 / CaMKIV / ポドサイト / ループス腎炎 Less

The construction of clinical predictive models and molecular models for PM/DM-ILD progressing to progressive pulmonary fibrosis
- Principal Investigator
  
  清水俊匡
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
ナノリポソームを用いたドラッグデリバリーによる自己炎症性疾患の治療戦略
- Principal Investigator
  
  梅田雅孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Comprehensive disease-associated interactome and model mice elucidate diversity and periodicity of the autoinflammatory disease
- Principal Investigator
  
  増本純也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
特発性多中心性キャッスルマン病の病型をクラスタリングする分子基盤研究
- Principal Investigator
  
  川上純
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
家族性地中海熱の病態における免疫老化の意義を明らかにする研究Principal Investigator
- Principal Investigator
  
  古賀智裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
自己炎症のメカニズムに立脚した成人スチル病の分子病態の解明
- Principal Investigator
  
  浅野智之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Fukushima Medical University
パイリンインフラマソーム活性化メカニズムの解明とその制御法の開発
- Principal Investigator
  
  右田清志
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Fukushima Medical University
Comprehensive identification of responsible regulatory molecules that define the seizure periodicity and inflammatory diversity of autoinflammatory diseases
- Principal Investigator
  
  Masumoto Junya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
Pathology evaluation research of rheumatoid arthritis leading to the realization of precision medicine
- Principal Investigator
  
  Kawakami Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Development of biomarkers for "early diagnosis" and "realization of precision medicine" of familial Mediterranean feverPrincipal Investigator
- Principal Investigator
  
  Koga Tomohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease
- Principal Investigator
  
  KIRINO Yohei
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
Identification of "disease control system" of adult still disease based on whole exon sequencePrincipal Investigator
- Principal Investigator
  
  KOGA Tomohiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus.
- Principal Investigator
  
  UMEDA Masataka
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
Basic research for using MRI evaluating cartilage damage in rheumatoid arthritis
- Principal Investigator
  
  TAMAI Mami
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
Basic research for searching of new therapeutic targets of rheumatoid arthritis through investigation of novel action of CTLA-4-Ig
- Principal Investigator
  
  KAWAKAMI Atsushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
CaMK4 inhitotion in rheumatoid arthritis for the immunological remissionPrincipal Investigator
- Principal Investigator
  
  KOGA Tomohiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University
Role of calcium/calmodulin kinase IV on podocyte function in lupus nephritis
- Principal Investigator
  
  ICHINOSE Kunihiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nagasaki University
RNAレギュロンによる関節リウマチのシトルリン化抗原発現機序の解明Principal Investigator
- Principal Investigator
  
  古賀智裕
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nagasaki University

[Journal Article] Diagnostic challenges of the idiopathic plasmacytic lymphadenopathy (IPL) subtype of idiopathic multicentric Castleman disease (iMCD): Factors to differentiate from IgG4-related disease2024
- Author(s)
  Nishikori Asami、Nishimura Midori Filiz、Fajgenbaum David C、Nishimura Yoshito、Maehama Kanna、Haratake Tomoka、Tabata Tetsuya、Kawano Mitsuhiro、Nakamura Naoya、Momose Shuji、Sumiyoshi Remi、Koga Tomohiro、Yamamoto Hidetaka、van Rhee Frits、Kawakami Atsushi、Sato Yasuharu
- Journal Title
  
  Journal of Clinical Pathology
  
  Volume: 20 Pages: jcp-2023-209280
- DOI
  10.1136/jcp-2023-209280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14476, KAKENHI-PROJECT-22K08524
[Journal Article] キャッスルマン病・TAFRO症候群の病態：抹消血液細胞やサイトカインの観点から2023
- Author(s)
  古賀智裕、住吉玲美、福井翔一、川上純
- Journal Title
  
  炎症と免疫
  
  Volume: 31 Pages: 53-57
- Data Source
  KAKENHI-PROJECT-22K08524
[Journal Article] Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease2023
- Author(s)
  Harada Takuya、Kikushige Yoshikane、Miyamoto Toshihiro、Uno Kazuko、Niiro Hiroaki、Kawakami Atsushi、Koga Tomohiro、Akashi Koichi、Yoshizaki Kazuyuki
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6959-6959
- DOI
  10.1038/s41467-023-42718-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08524, KAKENHI-PROJECT-21K08460, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-23K24364
[Journal Article] Exploring the role of insulin-like growth factor binding protein-1 in identifying idiopathic multicentric Castleman's disease types: Implications for the mTOR signaling pathway2023
- Author(s)
  Sumiyoshi Remi、Koga Tomohiro、Fukui Shoichi、Furukawa Kaori、Momoki Mamiko、Ichinose Kunihiro、Yano Shingo、Kawakami Atsushi
- Journal Title
  
  Clinical Immunology
  
  Volume: 256 Pages: 109798-109798
- DOI
  10.1016/j.clim.2023.109798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08524, KAKENHI-PROJECT-22K08544
[Journal Article] キャッスルマン病・TAFRO症候群レジストリ研究2023
- Author(s)
  古賀智裕, 住吉玲美, 細萱直希, 川上純
- Journal Title
  
  リウマチ科
  
  Volume: 69 Pages: 499-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08524
[Journal Article] キャッスルマン病・TAFRO症候群の疾病登録システム2023
- Author(s)
  住吉玲美、福井翔一、古賀智裕、川上純
- Journal Title
  
  炎症と免疫
  
  Volume: 31 Pages: 73-76
- Data Source
  KAKENHI-PROJECT-22K08524
[Journal Article] Identification of risk factors for elevated serum IgG4 levels in subjects in a large-scale health checkup cohort study2023
- Author(s)
  Tsuji Yoshika、Koga Tomohiro、Nonaka Fumiaki、Nobusue Kenichi、Kawashiri Shin-ya、Yamanashi Hirotomo、Maeda Takahiro、Arima Kazuhiko、Aoyagi Kiyoshi、Takahashi Meiko、Kawaguchi Shuji、Matsuda Fumihiko、Fujii Hiroshi、Kawano Mitsuhiro、Nakamura Hiroyuki、Kawakami Atsushi、Tamai Mami
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1124417-1124417
- DOI
  10.3389/fimmu.2023.1124417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08473, KAKENHI-PROJECT-22K08327, KAKENHI-PROJECT-22K19686, KAKENHI-PROJECT-19H03882, KAKENHI-PROJECT-22K08544
[Journal Article] 特発性多中心性キャッスルマン病とTAFRO症候群2023
- Author(s)
  古賀智裕、住吉玲美、川上純
- Journal Title
  
  リウマチ科
  
  Volume: 71 Pages: 238-243
- Data Source
  KAKENHI-PROJECT-22K08524
[Journal Article] Interleukin-6 inhibition in the treatment of autoinflammatory diseases2022
- Author(s)
  Koga T, Kawakami A
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.956795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08524, KAKENHI-PROJECT-22K08544
[Journal Article] Autoinflammatory disease: clinical perspectives and therapeutic strategies2022
- Author(s)
  Kawakami Atsushi、Endo Yushiro、Koga Tomohiro、Yoshiura Koh-ichiro、Migita Kiyoshi
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 37-37
- DOI
  10.1186/s41232-022-00217-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08544, KAKENHI-PROJECT-19K17888
[Journal Article] Candidate biomarkers for idiopathic multicentric Castleman disease2022
- Author(s)
  Sumiyoshi R, Koga T, Kawakami A
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 62 Issue: 2 Pages: 85-90
- DOI
  10.3960/jslrt.22010
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08524
[Journal Article] Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis2021
- Author(s)
  Koga T, Furukawa K, Migita K, Morimoto S, Shimizu T, Fukui S, Umeda M, Endo Y, Sumiyoshi R, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Origuchi T, Maeda T, Yachie A, Kawakami A.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 23 Issue: 1 Pages: 260-260
- DOI
  10.1186/s13075-021-02644-2
- NAID
  120007180588
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08913, KAKENHI-PROJECT-21K20905
[Journal Article] Methotrexate Alters the Expression of microRNA in Fibroblast-like Synovial Cells in Rheumatoid Arthritis2021
- Author(s)
  Iwamoto N、Furukawa K、Endo Y、Shimizu T、Sumiyoshi R、Umeda M、Koga T、Kawashiri S-Y、Igawa T、Ichinose K、Tamai M、Origuchi T、Kawakami A
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11561-11561
- DOI
  10.3390/ijms222111561
- NAID
  120007180579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-21K08439
[Journal Article] Fluorescence optical imaging in patients with active rheumatoid arthritis: a comparison with ultrasound and an association with biomarkers2021
- Author(s)
  Kawashiri SY, Nishino A, Shimizu T, Takatani A, Umeda M, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Maeda T, Kawakami A.
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 50 Issue: 2 Pages: 95-103
- DOI
  10.1080/03009742.2020.1794028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08886
[Journal Article] Current insights and future prospects for the pathogenesis and treatment for rheumatoid arthritis2021
- Author(s)
  Koga T, Kawakami A, Tsokos GC.
- Journal Title
  
  Clinical Immunology
  
  Volume: 225 Pages: 108680-108680
- DOI
  10.1016/j.clim.2021.108680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08886
[Journal Article] Ultrasound efficacy of targeted-synthetic disease-modifying anti-rheumatic drug treatment in rheumatoid arthritis: a multicenter prospective cohort study in Japan2021
- Author(s)
  Endo Y、Kawashiri S-Y、Nishino A、Michitsuji T、Tomokawa T、Nishihata S、Okamoto M、Tsuji Y、Tsuji S、Shimizu T、Sumiyoshi R、Igawa T、Koga T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Otsubo H、Takaoka H、et al.
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: - Issue: 4 Pages: 1-9
- DOI
  10.1080/03009742.2021.1927389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-21K08439
[Journal Article] Effect of abatacept treatment on serum osteoclast-related biomarkers in patients with rheumatoid arthritis (RA)2021
- Author(s)
  Kawashiri S-Y、Endo Y、Nishino A、Okamoto M、Tsuji S、Takatani A、Shimizu T、Sumiyoshi R、Koga T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Aramaki T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Hamada H、Nagano S、Tada Y、Kawakami A
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 28 Pages: e26592-e26592
- DOI
  10.1097/md.0000000000026592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-21K08439
[Journal Article] Tocilizumab has no direct effect on cell lines infected with human T-cell　leukemia virus type 1.2021
- Author(s)
  Endo Y, Fukui S, Koga T, Sasaki D, Hasegawa H, Yanagihara K, Okayama A, Nakamura T, Kawakami A, Nakamura H. Tocilizumab has no direct effect on cell lines infected with human T-cell　leukemia virus type 1.
- Journal Title
  
  J Int Med Res.
  
  Volume: 49 Issue: 3 Pages: 1-10
- DOI
  10.1177/03000605211002083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08884, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-19K17888
[Journal Article] Utility of a simplified ultrasonography scoring system among patients with rheumatoid arthritis2021
- Author(s)
  Endo Yushiro、Kawashiri Shin-ya、Morimoto Shimpei、Nishino Ayako、Okamoto Momoko、Tsuji Sosuke、Takatani Ayuko、Shimizu Toshimasa、Sumiyoshi Remi、Igawa Takashi、Koga Tomohiro、Iwamoto Naoki、
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 1 Pages: e23254-e23254
- DOI
  10.1097/md.0000000000023254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-19K17888
[Journal Article] Discrepancy between clinical and ultrasound remissions in rheumatoid arthritis: a multicentre ultrasound cohort study in Japan2021
- Author(s)
  Endo Y、Kawashiri S-Y、Nishino A、Okamoto M、Tsuji S、Shimizu T、Sumiyoshi R、Igawa T、Koga T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Otsubo H、Takaoka H、Hamada H、Tsuru T、Nagano S、Arinobu Y、Hidaka T、Tada Y、Kawakami A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 50 Issue: 6 Pages: 436-441
- DOI
  10.1080/03009742.2021.1876914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-19K17888
[Journal Article] The possession of exon 2 or exon 3 variants in the MEFV gene promotes inflammasome activation in Japanese patients with familial Mediterranean fever with a heterozygous exon 10 mutation2020
- Author(s)
  Yushiro Endo, Tomohiro Koga, Kazusato Hara, Kaori Furukawa, Kazunaga Agematsu, Akihiro Yachie, Junya Masumoto, Kiyoshi Migita, Atsushi Kawakami.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 38 Suppl 127 Pages: 49-52
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03719
[Journal Article] Effectiveness and safety of non-tumor necrosis factor inhibitor therapy for anti-human T-cell leukemia virus type 1 antibody-positive rheumatoid arthritis2020
- Author(s)
  Endo Yushiro、Fukui Shoichi、Umekita Kunihiko、Kawakami Atsushi、Nakamura Hideki、et al
- Journal Title
  
  Modern Rheumatology
  
  Volume: － Issue: 5 Pages: 972-978
- DOI
  10.1080/14397595.2020.1847802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17888, KAKENHI-PROJECT-19K08884, KAKENHI-PROJECT-19K08886
[Journal Article] Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: a case-control association study2020
- Author(s)
  Koga T, Sato S, Mishima H, Migita K, Endo Y, Umeda M, Sumiyoshi R, Nonaka F, Fukui S, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Masumoto J, Agematsu K, Yachie A, Yoshiura KI, Eguchi K, Kawakami A.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: 38 Pages: 35-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08913
[Journal Article] Contributing factors of clinical outcomes at 1 year post-diagnosis in early rheumatoid arthritis patients with tightly controlled disease activity in clinical practice: a retrospective study2020
- Author(s)
  Kawashiri S-Y、Endo Y、Okamoto M、Tsuji S、Shimizu T、Sumiyoshi R、Koga T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Kawakami A
- Journal Title
  
  Modern Rheumatology
  
  Volume: 31 Issue: 2 Pages: 343-349
- DOI
  10.1080/14397595.2020.1795392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-19K08886
[Journal Article] Significance of anti-Ro/SSA antibodies in the response and retention of abatacept in patients with rheumatoid arthritis: a multicentre cohort study2020
- Author(s)
  Endo Y、Koga T、Kawashiri S-Y、Morimoto S、Nishino A、Okamoto M、Tsuji S、Takatani A、Shimizu T、Sumiyoshi R、Igawa T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Hamada H、Tsuru T、Nagano S、Arinobu Y、Hidaka T、Tada Y、Kawakami A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 50 Issue: 1 Pages: 15-19
- DOI
  10.1080/03009742.2020.1772361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886
[Journal Article] Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: a case-control association study2020
- Author(s)
  Tomohiro Koga, Shuntaro Sato, Hiroyuki Mishima, Kiyoshi Migita, Yushiro Endo, Masataka Umeda, Remi Sumiyoshi, Fumiaki Nonaka, Shoichi Fukui, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Junya Masumoto,et al.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 38 Suppl 127 Pages: 35-41
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03719
[Journal Article] KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1β from PBMCs in a patient with Muckle?Wells syndrome2020
- Author(s)
  Kaneko Naoe、Kurata Mie、Yamamoto Toshihiro、Shigemura Tomonari、Agematsu Kazunaga、Yamazaki Takashi、Takeda Hiroyuki、Sawasaki Tatsuya、Koga Tomohiro、Kawakami Atsushi、Yachie Akihiro、Migita Kiyoshi、Yoshiura Koh-ichiro、Urano Takeshi、Masumoto Junya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13562-13562
- DOI
  10.1038/s41598-020-70513-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07376, KAKENHI-PROJECT-18KK0245, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H03719, KAKENHI-PROJECT-20H01085
[Journal Article] The possession of exon 2 or exon 3 variants in the MEFV gene promotes inflammasome activation in Japanese patients with familial Mediterranean fever with a heterozygous exon 10 mutation2020
- Author(s)
  Endo Y, Koga T, Hara K, Furukawa K, Agematsu K, Yachie A, Masumoto J, Migita K, Kawakami A.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: 38 Pages: 49-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08913
[Journal Article] Non-TNF inhibitor switchers versus TNF inhibitor cyclers from multicentre rheumatoid arthritis ultrasonography prospective cohort in Japan2020
- Author(s)
  Endo Y、Koga T、Kawashiri S-Y、Morimoto S、Nishino A、Okamoto M、Tsuji S、Takatani A、Shimizu T、Sumiyoshi R、Igawa T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Hamada H、Tsuru T、Nagano S、Arinobu Y、Hidaka T、Tada Y、Kawakami A
- Journal Title
  
  Immunological Medicine
  
  Volume: 43 Issue: 3 Pages: 115-120
- DOI
  10.1080/25785826.2020.1757920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-19K08910, KAKENHI-PROJECT-18K08411
[Journal Article] Rheumatoid arthritis patients with low baseline Health Assessment Questionnaire scores have a risk of functional disability progression: A post hoc analysis of a nationwide longitudinal cohort in Japan.2020
- Author(s)
  Sumiyoshi R, Hidaka T, Koga T, Okada A, Fukuda T, Ishii T, Ueki Y, Kodera T, Nakashima M, Takahashi Y, Honda S, Horai Y, Watanabe R, Okuno H, Aramaki T, Izumiyama T, Takai O, Miyashita T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Eguchi K, Kawakami A.
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08886
[Journal Article] Anti-citrullinated protein antibody titre as a predictor of abatacept treatment persistence in patients with rheumatoid arthritis: a prospective cohort study in Japan2019
- Author(s)
  Endo Y、Koga T、Kawashiri S-Y、Morimoto S、Nishino A、Okamoto M、Eguchi M、Tsuji S、Takatani A、Shimizu T、Sumiyoshi R、Igawa T、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Yoshitama T、Eiraku N、Matsuoka N、Okada A、Fujikawa K、Hamada H、Tsuru T、Nagano S、Arinobu Y、Hidaka T、Tada Y、Kawakami A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 49 Issue: 1 Pages: 13-17
- DOI
  10.1080/03009742.2019.1627411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08885, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-19K08910
[Journal Article] CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus.2018
- Author(s)
  Umeda M, Koga T, Ichinose K(corresponding author), Igawa T, Sato T, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Hirai Y, Kawashiri SY, Iwamoto N, Aramaki T, Tamai M, Nakamura H, Yamamoto K, Abiru N, Origuchi T, Ueki Y, Kawakami A.
- Journal Title
  
  Clin Immunol.
  
  Volume: 187 Pages: 50-57
- DOI
  10.1016/j.clim.2017.10.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09977, KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-16K19604, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16H06276
[Journal Article] Ultrasonographic efficacy of biologic and targeted synthetic DMARDs therapy in RA from multicenter RA ultrasound prospective cohort in Japan2018
- Author(s)
  Nishino Ayako、Kawashiri Shin-ya、Koga Tomohiro、Iwamoto Naoki、Ichinose Kunihiro、Tamai Mami、Nakamura Hideki、Origuchi Tomoki、Ueki Yukitaka、Yoshitama Tamami、Eiraku Nobutaka、Matsuoka Naoki、Okada Akitomo、Fujikawa Keita、Hamada Hiroaki、Tsuru Tomomi、Nagano Shuji、Arinobu Yojiro、Hidaka Toshihiko、Kawakami Atsushi
- Journal Title
  
  Arthritis Care & Research
  
  Volume: 26 Issue: 12 Pages: 1719-1726
- DOI
  10.1002/acr.23551
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-16K09897, KAKENHI-PROJECT-15K19576, KAKENHI-PROJECT-15K01371, KAKENHI-PROJECT-16K19605
[Journal Article] M1 and M2 Monocytes in Rheumatoid Arthritis: A Contribution of Imbalance of M1/M2 Monocytes to Osteoclastogenesis2018
- Author(s)
  Fukui Shoichi、Iwamoto Naoki、Takatani Ayuko、Igawa Takashi、Shimizu Toshimasa、Umeda Masataka、Nishino Ayako、Horai Yoshiro、Hirai Yasuko、Koga Tomohiro、Kawashiri Shin-ya、Tamai Mami、Ichinose Kunihiro、Nakamura Hideki、Origuchi Tomoki、Masuyama Ritsuko、Kosai Kosuke、Yanagihara Katsunori、Kawakami Atsushi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 8 Pages: 1958-1958
- DOI
  10.3389/fimmu.2017.01958
- NAID
  120006987316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K19771, KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-17H01967, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16K19606
[Journal Article] Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway2018
- Author(s)
  Iwamoto Naoki、Fukui Shoichi、Takatani Ayuko、Shimizu Toshimasa、Umeda Masataka、Nishino Ayako、Igawa Takashi、Koga Tomohiro、Kawashiri Shin-ya、Ichinose Kunihiro、Tmai Mami、Nakamura Hideki、Origuchi Tomoki、Chiba Ko、Osaki Makoto、J?ngel Astrid、Gay Steffen、Kawakami Atsushi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 20 Issue: 1 Pages: 189-189
- DOI
  10.1186/s13075-018-1703-z
- NAID
  120006987960
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-15K09531
[Journal Article] Comparison of serum inflammatory cytokine concentrations in familial Mediterranean fever and rheumatoid arthritis patients2017
- Author(s)
  Koga T、Kawashiri S-y、Migita K、Sato S、Umeda M、Fukui S、Nishino A、Nonaka F、Iwamoto N、Ichinose K、Tamai M、Nakamura H、Origuchi T、Ueki Y、Masumoto J、Agematsu K、Yachie A、Eguchi K、Kawakami A
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: - Issue: 4 Pages: 1-3
- DOI
  10.1080/03009742.2017.1363281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-15H04783, KAKENHI-PROJECT-26461481, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-15H04873
[Journal Article] Baseline MRI bone erosion predicts the subsequent radiographic progression in early rheumatoid arthritis patients who achieve d sustained good clinical response2017
- Author(s)
  Tamai M, Arima K, Nakashima Y, Kita J, Umeda M, Fukui S, Nishino A, Suzuki T, Horai Y, Okada A, Koga T, Kawashiri S-Y, Iwamoto N, Ichinose K, Yamasaki S, Nakamura H, Origuchi T, Aoyagi K, Uetani M, Eguchi K, Kawakami A
- Journal Title
  
  Modern Rheumatology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09530
[Journal Article] TNF-α-induced miR-155 regulates IL-6 signaling in rheumatoid synovial fibroblasts2017
- Author(s)
  Migita Kiyoshi、Iwanaga Nozomi、Izumi Yasumori、Kawahara Chieko、Kumagai Kenji、Nakamura Tadashi、Koga Tomohiro、Kawakami Atsushi
- Journal Title
  
  BMC Research Notes
  
  Volume: 10 Issue: 1 Pages: 403-403
- DOI
  10.1186/s13104-017-2715-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09531
[Journal Article] Baseline MRI bone erosion predicts the subsequent radiographic progression in early rheumatoid arthritis patients who achieved sustained good clinical response.2017
- Author(s)
  Tamai M, Arima K, Nakashima Y, Kita J, Umeda M, Fukui S, Nishino A, Suzuki T, Horai Y, Okada A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Yamasaki S, Nakamura H, Origuchi T, Aoyagi K, Uetani M, Eguchi K, Kawakami A
- Journal Title
  
  Mod Rheumatol
  
  Volume: 印刷中 Issue: 6 Pages: 1-6
- DOI
  10.1080/14397595.2017.1294280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461829, KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K16210
[Journal Article] The role of CaMK4 in immune responses2017
- Author(s)
  Koga Tomohiro、Kawakami Atsushi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 28 Issue: 2 Pages: 211-214
- DOI
  10.1080/14397595.2017.1413964
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09531
[Journal Article] MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway2017
- Author(s)
  Koga Tomohiro,Migita Kiyoshi,Sato Tomohito,Sato Shuntaro,Umeda Masataka,Nonaka Fumiaki,Fukui Shoichi,Kawashiri Shin-ya,Iwamoto Naoki,Ichinose Kunihiro,Tamai Mami,Nakamura Hideki,Origuchi Tomoki,Ueki Yukitaka,Masumoto Junya,Agematsu Kazunaga,Yachie Akihiro,Yoshiura Koh-ichiro,Eguchi Katsumi,Kawakami Atsushi
- Journal Title
  
  Rheumatology
  
  Volume: 57 Issue: 4 Pages: 718-726
- DOI
  10.1093/rheumatology/kex451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-16K15514, KAKENHI-PROJECT-26461481, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16KT0112, KAKENHI-PROJECT-15H04873, KAKENHI-PROJECT-16H05159, KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17K19685
[Journal Article] Familial Mediterranean fever complicated with refractory asthma: Successful treatment with colchicine.2017
- Author(s)
  Koga T, Fukushima C, Umeda M, Migita K, Kawakami A.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 27 Issue: 1 Pages: 182-183
- DOI
  10.3109/14397595.2016.1173000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15514
[Journal Article] Fewer subsequent relapses and lower levels of IL-17 in Takayasu arteritis developed after the age of 40 years.2016
- Author(s)
  Fukui S, Iwamoto N, Shimizu T, Umeda M, Nishino A, Koga T, Kawashiri SY, Ichinose K, Hirai Y, Tamai M, Nakamura H, Aramaki T, Iwanaga N, Izumi Y, Origuchi T, Migita K, Ueki Y, Sato S, Kawakami A.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13 Issue: 1 Pages: 293-293
- DOI
  10.1186/s13075-016-1193-9
- NAID
  120006987596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09531
[Journal Article] CaMK4 facilitates the recruitment of IL-17-producing cells to target organs through the CCR6/CCL20 axis in Th17-driven inflammatory diseases.2016
- Author(s)
  Koga T, Otomo K, Mizui M, Yoshida N, Umeda M, Ichinose K, Kawakami A, Tsokos GC
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: in press Issue: 8 Pages: 1981-1988
- DOI
  10.1002/art.39665
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893198
[Journal Article] Multiple Serum Cytokine Profiling to Identify Combinational Diagnostic Biomarkers in Attacks of Familial Mediterranean Fever.2016
- Author(s)
  Koga T, Migita K, Sato S, Umeda M, Nonaka F, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Masumoto J, Agematsu K, Yachie A, Yoshiura K, Eguchi K, Kawakami A.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 95 Issue: 16 Pages: e3449-e3449
- DOI
  10.1097/md.0000000000003449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293232, KAKENHI-PROJECT-26305024, KAKENHI-PROJECT-16H05159, KAKENHI-PROJECT-16K15514
[Journal Article] MRI bone oedema at enrollment predicts rapid radiographic progression over 1 year in early rheumatoid arthritis patients: results from the Nagasaki University Early Arthritis Cohort2016
- Author(s)
  Nakashima Y, Tamai M, Kita J, Michitsuji T, Shimizu T, Fukui S, Umeda M, Nishino A, Suzuki S, Yoshiro Horai, Akitomo Okada, Takayuki Nishimura, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Yasuko Hirai, Arima K, Yamasaki S, Nakamura H, Origuchi T, Takao S, Uetani M, Aoyagi K, Eguchi K, Kawakami A
- Journal Title
  
  Journal of Rheumatology
  
  Volume: 43 Issue: 7 Pages: 7-13
- DOI
  10.3899/jrheum.150988
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09530, KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-26461829, KAKENHI-PROJECT-16K19605
[Journal Article] Brief report: increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice.2013
- Author(s)
  Ichinose K, Zhang Z, Koga T, Juang YT, Kis-Toth K, Sharpe AH, Kuchroo V, Crispin JC, Tsokos GC.
- Journal Title
  
  Arthritis Rheum.
  
  Volume: 65(3) Issue: 3 Pages: 764-9
- DOI
  10.1002/art.37790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790999
[Journal Article] Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus.2012
- Author(s)
  Koga T, Ichinose K, Mizui M, Crispin JC, Tsokos GC.
- Journal Title
  
  J Immunol.
  
  Volume: 189(7) Issue: 7 Pages: 3490-6
- DOI
  10.4049/jimmunol.1201785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790999
[Journal Article] A Japanese case of familial Mediterranean fever presenting diffuse bone marrow uptake of FDG-PET and high levels of neutrophil membrane CD64 expression.2011
- Author(s)
  Koga T, et al.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: Feb9(Epub ahead of print)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790936
[Journal Article] Expression of CD64 on polymorphonuclear neutrophils in patients with familial Mediterranean fever.2011
- Author(s)
  Migita K, Agematsu K, Yamazaki K, Suzuki A, Yazaki M, Jiuchi Y, Miyashita T, Izumi Y, Koga T, et al.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: Mar25(Epub ahead of print)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790936
[Journal Article] Induction of interleukin-23 p19 by serum amyloid A (SAA) in rheumatoid synoviocytes.2010
- Author(s)
  Migita K, Koga T, et al
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 162(2) Pages: 244-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790936
[Patent] スティル病と敗血症との鑑別用バイオマーカー2018
- Inventor(s)
  古賀智裕
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-083489
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K15514
[Presentation] Generation and pathophysiological analysis of knock-in mice of M694I variant of human MEFV gene2023
- Author(s)
  Tomohiro Koga, Yoshika Tsuji, Atsushi Kawakami
- Organizer
  JCR 2023 International Concurrent Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08544
[Presentation] 難治性の特発性多中心性キャッスルマン病,TAFRO症候群に対してシロリムスを投与した8例の経験2023
- Author(s)
  住吉玲美、古賀智裕、大塚瑞奈、來留島章太、道辻徹、梅田雅孝、福井翔一、川上純
- Organizer
  第51回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K08524
[Presentation] 疾患概念が不明であった希少難病のキャッスルマン病の病態解析～免疫異常疾患であることを示唆～2023
- Author(s)
  吉崎和幸、川上純、古賀智裕
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08524
[Presentation] キャッスルマン病・TAFRO症候群のレジストリ研究2023
- Author(s)
  川上　純，古賀智裕，住吉玲美，清水俊匡，細萱直希，森本心平，正木康史，矢野真吾，清水隆之，吉崎和幸，水木満佐央，中村直哉，佐藤康晴，新納宏昭
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08524
[Presentation] Identification of pathways that discriminate between TAFRO type and NOS type in idiopathic multicentric Castleman’s disease2023
- Author(s)
  Sumiyoshi R,Koga T,Koto S，Kurushima S，Tsuji Y，Michitsuji T，Umeda M，Kawakami A
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08524
[Presentation] 自己炎症性疾患診断の進め方とポイント2023
- Author(s)
  川上純、辻良香、住吉玲美、大塚瑞奈、福井翔一、古賀智裕
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08524
[Presentation] Granulocyte-macrophage colony stimulating factor and tumor necrosis factor α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis2021
- Author(s)
  Tomohiro Koga, Kiyoshi Migita, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Atsushi Kawakami
- Organizer
  第65回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-19K08913
[Presentation] 無細胞インフラマソーム再構成系による自己炎症疾患に対する分子標的薬の開発2021
- Author(s)
  増本純也, 金子直恵, 倉田美恵, 山本敏弘, 重村倫成, 上松一永, 山崎崇志, 谷内江昭宏, 浦野健, 右田清志, 吉浦孝一郎, 古賀智裕, 川上純.
- Organizer
  第4回日本免疫不全・自己炎症学会総会・学術集会 2021年　2月6～7日
- Invited
- Data Source
  KAKENHI-PROJECT-20H03719
[Presentation] 住民健康診断における関節リウマチと抗CCP抗体に着目した口腔内細菌叢解析.2020
- Author(s)
  辻　良香，玉井慎美，川尻真也，野中文陽，有馬和彦，梅津彩香，原　万怜，道辻　徹，西畑伸哉，岡本百々子，遠藤友志郎，辻　創介，髙谷亜由子，井川　敬，住吉玲美，清水俊匡，古賀智裕，岩本直樹，一瀬邦弘，中村英樹，折口智樹，川上　純.
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] 無細胞NLRP3インフラマソーム再構成系によるMuckle-Wells症候群に対する分子標的薬の開発2020
- Author(s)
  増本純也, 重村倫成, 重村倫成, 上松一永, 山崎崇志, 谷内江昭宏, 浦野健, 右田清志, 吉浦孝一郎, 古賀智裕, 川上純.
- Organizer
  第64回日本リウマチ学会総会・学術集会 , 2020年　8月17日～9月15日
- Data Source
  KAKENHI-PROJECT-20H03719
[Presentation] Inhibition of calcium/calmodulindependent protein kinase IV in rheumatoid arthritis: Dual effect on Th17 cell activation and osteoclastogenesis.2020
- Author(s)
  Koga T, Sumiyoshi R, Shimizu T, Igawa T, Kawashiri S, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A.
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] Combined effect of common variants in exon 2 or exon 3 and a pathogenic mutation in exon 10 of the Mediterranean fever gene on inflammasome activation in Japanese patients with familial Mediterranean fever2020
- Author(s)
  Tomohiro Koga, Yushiro Endo, Kaori Furukawa, Kazunaga Agematsu, Akihiro Yachie, Junya Masumoto, Kiyoshi Migita, Atsushi Kawakami
- Organizer
  欧州リウマチ学会2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08913
[Presentation] HR-pQCTを用いた関節リウマチ治療経過における関節構造変化の解析.2020
- Author(s)
  岩本直樹, 渡邉之助，白石和輝，大木望，千葉　恒，古賀　智裕，川尻真也, 一瀬邦弘，玉井慎美，中村英樹，折口　智樹，尾崎誠，川上　純.
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] 次世代シーケンサーを用いた日本全域の家族性地中海熱患者におけるMEFV遺伝子の包括的解析2019
- Author(s)
  古賀智裕, 右田清志, 遠藤友志郎, 住吉玲美, 野中文陽, 江口勝美, 川上純
- Organizer
  第116回日本内科学会講演会　プレナリーセッション
- Invited
- Data Source
  KAKENHI-PROJECT-19K08913
[Presentation] 関節リウマチ患者におけるMRIとUSを用いたX線進行の予測因子の検討.2019
- Author(s)
  高谷亜由子, 玉井慎美, 大木　望, 清水俊匡, 住吉玲美, 古賀智裕, 川尻真也, 岩本直樹, 井川　敬, 一瀬邦弘, 有馬和彦, 中村英樹, 折口智樹, 上谷雅孝, 川上　純.
- Organizer
  第47回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] HR-pQCTによる関節リウマチ治療経過における骨微細構造変化の解析.2019
- Author(s)
  岩本直樹, 渡邉航之助，千葉　恒，古賀智裕，川尻真也，一瀬邦弘，玉井慎美，中村英樹，折口智樹，川上　純．
- Organizer
  第34回日本臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] MRIによる関節リウマチの関節裂隙狭小化の評価.2019
- Author(s)
  玉井慎美, 高谷亜由子, 大木　望, 上谷雅孝岩本直樹, 古賀　智裕, 有馬和彦, 青柳潔, 川上　純.
- Organizer
  第47回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: case-control association study2019
- Author(s)
  Tomohiro Koga, Kiyoshi Migita, Yushiro Endo, Remi Sumiyoshi, Fumiaki Nonaka, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Kazunaga Agematsu, Junya Masumoto, Akihiro Yachie, Katsumi Eguchi, Atsushi Kawakami
- Organizer
  日本リウマチ学会（JCR 2019 International Concurrent Workshop ）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08913
[Presentation] 関節リウマチにおけるカルシウム/カルモジュリン依存性プロテインキナーゼⅣの阻害はTh細胞活性化と破骨細胞形成に対する二重の作用を有する.2019
- Author(s)
  古賀智裕, 佐藤智仁, 古川かおり, 岩本直樹, 一瀬邦弘, 川上　純.
- Organizer
  第47回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] Inhibition of Calcium/calmodulin-dependent Protein Kinase IV in Rheumatoid Arthritis: Dual Effect on Th17 Cell Activation and Osteoclastogenesis.2019
- Author(s)
  Koga T, Sato T, Endo Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Kawashiri S, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Yoshida N, Umeda M, Tsokos G and kawakami A.
- Organizer
  2019 ACR/ARP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] 関節リウマチ患者におけるＸ線進行のリスク因子の検討.2019
- Author(s)
  髙谷亜由子,玉井慎美, 大木　望, 中島好一,大塚瑞奈,岡本百々子,遠藤友志郎, 辻　創介, 清水俊匡, 住吉玲美, 古賀智裕, 川尻真也,岩本直樹, 井川　敬, 一瀬邦弘, 有馬和彦,中村英樹, 折口智樹,上谷雅孝,川上　純.
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] 関節リウマチにおけるHR-pQCTを用いた中手骨頭骨微細構造と骨膜炎，腰椎大腿骨骨密度，骨破壊進行度の関連解析.2019
- Author(s)
  岩本直樹，大塚瑞奈，岡本百々子，遠藤友志郎，辻　創介，髙谷亜由子，清水俊匡，住吉玲美，古賀智裕，川尻真也，井川　敬，一瀬邦弘，玉井慎美，中村英樹，大木　望，渡邉航之助，千葉　恒，折口智樹，尾崎　誠，川上　純．
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08886
[Presentation] Serum fibroblast growth factor 2 is a useful biomarker to distinguish adult onset still disease from sepsis2018
- Author(s)
  Tomohiro Koga, Remi Sumiyoshi, Shuntaro Sato, Kiyoshi Migita, Toshimasa Shimizu, Masataka Umeda, Fumiaki Nonaka, Shoichi Fukui, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Akihiro Yachie, Takahiro Maeda, Atsushi Kawakami
- Organizer
  欧州リウマチ学会（EULAR 2018）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15514
[Presentation] MicroRNA-887-3p have possibility of downstream effector of MTX in its antiproliferative activity toward fibroblast-like synovial cells in rheumatoid arthritis.2018
- Author(s)
  Iwamoto N, Tsuji S, Endo Y, Takatani A, Shimizu T, Umeda M, Fukui S, Igawa T,Koga T, Kawashiri S, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A.
- Organizer
  20th Asia Pacific League of Associations for Rheumatology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] Combination of Ultrasound Power Doppler-Verfied Synovitis and Seropositivity Accurately Identifies Patients with Early Rheumatoid Arthritis.2018
- Author(s)
  Kawashiri SY, Fujikawa k, Nishino A, Takatani A, Shimizu T, Umeda M, Fukui S, Igawa T, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A.
- Organizer
  2018 ACR/ARHP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] 関節リウマチと歯周疾患2017
- Author(s)
  玉井慎美、清水俊匡、高谷亜由子、梅田雅孝、福井翔一、西野文子、古賀智裕、川尻;真也、岩本直樹、一瀬邦弘、中村英樹、折口智樹、川下由美子、梅田正博、上谷雅孝、佐藤俊太朗、川上純
- Organizer
  第45回日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-15K09530
[Presentation] 関節リウマチにおけるMRIと超音波検査(US)を用いたX線進行のリスク因子の検討2017
- Author(s)
  髙谷亜由子、玉井慎美、大木望、遠藤友志郎、辻創介、井川敬、清水俊匡、梅田雅孝、福井翔一、西野文子、古賀智裕、川尻真也、岩本直樹、一瀬邦弘、中村英樹、折口智樹、上谷雅孝、川上純
- Organizer
  第32回日本臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-15K09530
[Presentation] The CD4+CD52low T cell Contributes to the Development of Systemic Lupus Erythematosus through the CCR8/TARC Pathway2017
- Author(s)
  Umeda M, Koga T, Ichinose K, Igawa T, Kurushima S, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Kawashiri S, Iwamoto N, Hirai Y, Tamai M, Nakamura H, Origuchi T, Kawakami A
- Organizer
  Japan college of Rheumatology International Concurrent Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19604
[Presentation] miR-204-3P Inhibits The pruduction of TLR-Related Cytokines in Familial Mediterranean Fever By Targeting The Pik3 Signaling2017
- Author(s)
  Koga T, Migita K, Umeda M, Nonaka F, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Origuchi T, Eguchi K, Kawakami A.
- Organizer
  Annual European Congress of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] Microrna Profiling of MTX-Treated Fibroblast-like Synovial cells in Rheumatoid Arthritis Revealed a Possibility of MICRORNA-887-3P as Novel Therapeutic Target of RA2017
- Author(s)
  Iwamoto N, Fukui S, Koga T, Kawashiri SY, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A.
- Organizer
  Annual European Congress of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] The CD4+CD52low T Cell Contributes to the Development of Systemic Lupus Erythematosus through the CCR8/TARC Pathway2016
- Author(s)
  T. Sato, M. Umeda, T. Koga, K. Ichinose, T. Igawa, S. Kurushima, T. Shimizu, S. Fukui, A. Nishino, Y. Horai, Y. Hirai, S.-Y. Kawashiri, N. Iwamoto, T. Aramaki, M. Tamai, H. Nakamura, T. Origuchi, Y. Ueki, A. Kawakami
- Organizer
  2016アメリカリウマチ学会
- Place of Presentation
  アメリカ　ワシントンDC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19604
[Presentation] Role of CaMK4 in the pathogenesis of rheumatoid arthritis2016
- Author(s)
  Tomohiro Koga,Masataka Umeda,Yasuko Hirai,Toru Michitsuji,Toshimasa Shimizu,Shoichi Fukui,Ayako Nishino,Yoshikazu Nakashima,Shin-ya Kawashiri,Naoki Iwamoto,Kunihiro Ichinose,Mami Tamai,Tomoki Origuchi,Hideki Nakamura,Atsushi Kawakami
- Organizer
  第60回日本リウマチ学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26893198
[Presentation] The CD4+CD52low Tcell contributes to Disease Activity and Autoantibody Production in Systemic Lupus Erythematosus2016
- Author(s)
  M. Umeda, T. Koga, K. Ichinose, T. Michitsuji, T. Shimizu, S. Fukui, A. Nishino, Y. Nakashima, T. Suzuki, Y. Horai, Y. Hirai, S.-Y. Kawashiri, N. Iwamoto, T. Aramaki, M. Tamai , H. Nakamura , T. Origuchi , Y. Ueki , A. Kawakami
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-16K19604
[Presentation] Preferential Distribution of M1 Monocytes in Anti-Cyclic Citrullinated Peptide Antibody Positive Patients with Rheumatoid Arthritis.2016
- Author(s)
  Fukui S, Iwamoto N, Shimizu T, Umeda M, Nishino A, Horai Y, Koga T, Kawashiri SY, Ichinese K, Hirai Y, Tamai M, Nakamura H, Origuchi T and Kawakami A.
- Organizer
  ACR/ARHP Annual Meeting 2016
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] MRI bone oedma at enrollment predicts the development of rapid radiographic progression at 1 year toward patients with early-stage rheumatoid arthritis: Results from Nagasaki University Early Arthritis Cohort2015
- Author(s)
  Nakashima Y, Tamai M, Kita J, Fukui S, Umeda M, Nishino A, Suzuki T, Horai Y, Okada A, Koga T, Kawashiri S-Y, Iwamoto N, Ichinose K, Hirai Y, Arima K, Nakamura H, Origuchi T, Uetani M, Aoyagi K, Eguchi K, Kawakami A
- Organizer
  European League Against Rheumatism 2015
- Place of Presentation
  Rome, Italy
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09530
[Presentation] 関節リウマチ患者におけるインドシアニングリーン増強蛍光光学画像検査の有用性2015
- Author(s)
  川尻真也，西野文子，梅田雅孝，福井翔一，中島好一，鈴木貴久，古賀智裕，岩本直樹，一瀬邦弘，玉井慎美，中村英樹，折口智樹，青栁　潔，川上　純
- Organizer
  第50回九州リウマチ学会
- Place of Presentation
  鹿児島県医師会館（鹿児島県　鹿児島市）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] MRI bone erosion at baseline predicts the subsequent radiographic progression in early-stage RA patients who achieved in sustained clinical good response: Sub-analysis from Nagasaki University Early Arthritis Cohort.2015
- Author(s)
  Tamai M, Nakashima Y, Arima K, Kita J, Umeda M, Fukui S, Nishino A, Suzuki T, Horai Y, Okada A, Koga T, Kawashiri S-Y, Iwamoto N, Ichinose K, Yamasaki S, Nakamura H, Origuchi T, Aoyagi K, Uetani M, Eguchi K, Kawakami A
- Organizer
  American College of Rheumatology 2015
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09530
[Presentation] MRI Bone Oedema at Enrollment Predicts the Development of Rapid Radiographic Progression at 1 year Toward Patients with Early-Stage Rheimatoid Arthritis: Results from Nagasaki University Arthritis Cohort.2015
- Author(s)
  Nakashima Y,Tamai M, Michitsuji T, Shimizu T, Fukui S, Umeda M, Nishino A, Koga T, Kawashiri S, Iwamoto N, Ichinose K, Hirai Y, Nakamura H, Origuchi T, and Kawakami A.
- Organizer
  ACR 2015
- Place of Presentation
  San Francisco　（USA）
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531
[Presentation] Role of calcium/calmodulin kinase IV on podocyte function in lupus nephritis2013
- Author(s)
  Kunihiro Ichinose, Takeshi Ushigusa, Tomohiro Koga, George C.Tsokos, Atsushi Kawakami
- Organizer
  The ACR/ARHP 2013 Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24790999
[Presentation] Role of calcium/calmodulin kinase IV on podocyte function in lupus nephritis2013
- Author(s)
  Kunihiro Ichinose, Takeshi Ushigusa, Tomohiro Koga, Geroge C. Tsokos, Atushi Kawakami
- Organizer
  IMMUNOLOGY 2013
- Place of Presentation
  Honolulu, HI, USA
- Data Source
  KAKENHI-PROJECT-24790999
[Presentation] Role of calcium/calmodulin kinase IV on podocyte function in lupus nephritis2013
- Author(s)
  Kunihiro Ichinose, Takeshi Ushigusa, Tomohiro Koga, George C.Tsokos, Atsushi Kawakami
- Organizer
  Immunology 2013
- Place of Presentation
  Honolulu, HI, USA
- Data Source
  KAKENHI-PROJECT-24790999
[Presentation] Post-transcriptional regulation of IL-6 by Zc3h12a in fibroblast-like synovial cells2010
- Author(s)
  Koga T, et al.
- Organizer
  ACR/ARHP10 Scientific Meeting
- Place of Presentation
  Atlanta, GA
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22790936
[Presentation] CaMK4 inhibition ameliorates the development of Th17 driven inflammatory diseases by preventing recruitment of IL-17 producing cells to target organs
- Author(s)
  Tomohiro Koga
- Organizer
  2014年米国リウマチ学会議(ACR 2014)
- Place of Presentation
  ボストン、米国
- Year and Date
  2014-11-14 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-26893198

1. KAWAKAMI Astushi (90325639)

# of Collaborated Projects: 11 results

# of Collaborated Products: 70 results
2. 右田清志 (60264214)

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# of Collaborated Products: 19 results
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45. 浅野智之 (20644115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 清水俊匡 (40770467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 坂本憲穂 (30448493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 辻良香 (10866297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 川上茂 (20322307)

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# of Collaborated Products: 0 results
50. 小迫英尊 (10291171)

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# of Collaborated Products: 0 results
51. 岸田大 (50467180)

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52. 山中聡士 (50853884)

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53. KURATA Mie

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# of Collaborated Products: 1 results
54. 遠藤友志郎

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# of Collaborated Products: 1 results
55. 上松一永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 川野充弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 錦織亜沙美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOGA Tomohiro 古賀 智裕

古賀 智裕 コガ トモヒロ

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家族性地中海熱の病態における免疫老化の意義を明らかにする研究Principal Investigator

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Development of biomarkers for "early diagnosis" and "realization of precision medicine" of familial Mediterranean feverPrincipal Investigator

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Identification of "disease control system" of adult still disease based on whole exon sequencePrincipal Investigator

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KOGA Tomohiro 古賀智裕

古賀智裕コガトモヒロ