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Meng Hong Rui  孟 紅蕊

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MENG Hongrui  孟 紅蕊

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Researcher Number 90736498
Affiliation (Current) 2019: 順天堂大学, 医学(系)研究科(研究院), 博士研究員
Affiliation (based on the past Project Information) *help 2017 – 2018: 順天堂大学, 医学(系)研究科(研究院), 博士研究員
2017: 順天堂大学, 医学研究科, 研究員
2016: 順天堂大学, 医学(系)研究科(研究院), 特任研究員
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related
Except Principal Investigator
Pathological medical chemistry
Keywords
Principal Investigator
ミトコンドリア / パーキンソン病 / CHCHD2 / alpha-Synuclein / CHCHD2 / α-Synuclein
Except Principal Investigator
ミトコンドリア / ドーパミン神経 / iPS細胞 / リン酸化 … More / PINK1 / Parkin / CHCHD2 / iPS / ドパミン神経 / ショウジョウバエ / パーキンソン病 / ユビキチン / 酸化ストレス / 遺伝学 / シグナル伝達 / 神経変性 / キナーゼ / 神経変性疾患 Less
  • Research Projects

    (3 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (9 People)
  •  Analysis of the molecular mechanism by which mitochondrial dysfunction leads to alpha-Synaclein aggregationPrincipal InvestigatorOngoing

    • Principal Investigator
      孟 紅蕊
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University
  •  パーキンソン病原因遺伝子CHCHD2 が織りなすシグナルネットワークの究明Principal InvestigatorOngoing

    • Principal Investigator
      孟 紅蕊
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  A study on the common pathogenesis of Parkinson's disease as a mitochondrial disease

    • Principal Investigator
      Imai Yuzuru
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Juntendo University

All 2017 2016 2015

All Journal Article Presentation Book

  • [Book] Methods Mol Biol.2017

    • Author(s)
      Imai Y, Inoshita T, Shiba-Fukushima K, Meng H, Hattori N
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Journal Article] Monitoring Mitochondrial Changes by Alteration of the PINK1-Parkin Signaling in Drosophila2017

    • Author(s)
      Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Hongrui Meng, Nobutaka Hattori, Yuzuru Imai
    • Journal Title

      Methods in Molecular Biology

      Volume: 印刷中 Pages: 1-11

    • DOI
      10.1007/7651_2017_9
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19525, KAKENHI-PROJECT-16K09679
  • [Journal Article] Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c2017

    • Author(s)
      Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.
    • Journal Title

      Nature Commun

      Volume: 8 Pages: 15500-15500

    • DOI
      10.1038/ncomms15500
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K19525, KAKENHI-PROJECT-26293070, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-15KK0354, KAKENHI-PROJECT-17H01420
  • [Journal Article] Measurements of the mitochondrial respiration and glycolytic activity in Drosophila embryonic cells2017

    • Author(s)
      Meng Hongrui、Yamashita Chikara、Hattori Nobutaka、Imai Yuzuru
    • Journal Title

      Protocol Exchange

      Volume: -

    • DOI
      10.1038/protex.2017.069
    • Open Access
    • Data Source
      KAKENHI-PROJECT-16K19525
  • [Presentation] Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial cristae structure and facilitates cytochrome c release from mitochondria2017

    • Author(s)
      Meng Hongrui、Yamashita Chikara、Shiba-Fukushima Kahori、Inoshita Tsuyoshi、Imai Yuzuru、Hattori Nobutaka
    • Organizer
      日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K19525
  • [Presentation] Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial cristae structure and facilitates cytochrome c release from mitochondria2017

    • Author(s)
      Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Imai Y, Hattori N
    • Organizer
      第40回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Presentation] パーキンソン病新規原因遺伝子CHCHD2の機能解析2016

    • Author(s)
      山下 力、孟 紅蕊、井下強、福嶋佳保里、荒野拓、佐藤栄人、今居譲、服部信孝
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Presentation] パーキンソン病原因遺伝子によるシナプス小胞動態制御2016

    • Author(s)
      井下 強、荒野 拓、穂坂 有加、孟 紅蕊、梅崎 勇次郎、小杉 紗紀子、森本 高子、小池 正人、Hui-Yun Chang、服部 信孝、今居 譲
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Presentation] Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.2016

    • Author(s)
      Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Imai Y, Hattori N
    • Organizer
      第39回日本分子生物学会年会 シンポジウム
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Presentation] Mutations of mitochondrial protein CHCHD2 lead to parkinson’s disease-like phenotypes in Drosophila2016

    • Author(s)
      Hongrui Meng, Chikara Yamashita, Kahori Shiba, Tsuyoshi Inoshita, Manabu Funayama, Shigeto Sato, Yuzuru Imai, Nobutaka Hattori
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-16K19525
  • [Presentation] The Loss of Parkinson's Disease-Associated Protein CHCHD2 Affects Mitochondrial Cristae Structure and Destabilizes Cytochrome c2016

    • Author(s)
      Hongrui Meng, Chikara Yamashita, Kahori Shiba, Tsuyoshi Inoshita, Manabu Funayama, Shigeto Sato, Yuzuru Imai, Nobutaka Hattori
    • Organizer
      第39 回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-16K19525
  • [Presentation] CHCHD2, a Parkinson's-Disease Associated Protein, Regulates the Mitochondrial cristae integrity and function in Drosophila2016

    • Author(s)
      Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Imai Y, Hattori N
    • Organizer
      第39回日本神経学会学術大会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-26293070
  • [Presentation] CHCHD2, a Parkinson’s-Disease Associated Protein, Regulates the Mitochondrial cristae integrity and function in Drosophila2016

    • Author(s)
      Hongrui Meng, Chikara Yamashita, Kahori Shiba, Tsuyoshi Inoshita, Yuzuru Imai, Nobutaka Hattori
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-16K19525
  • [Presentation] Mutations of a mitochondrial protein CHCHD2 in Drosophila lead to Parkinson’s disease-like phenotypes2015

    • Author(s)
      Meng H, Yamashita C, Shiba-Fukushima K, Hattori N, Imai Y
    • Organizer
      Cell Symposia
    • Place of Presentation
      シカゴ
    • Year and Date
      2015-07-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293070
  • 1.  INOSHITA Tsuyoshi (20601206)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 2.  SHIBA Kahori (30468582)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  Imai Yuzuru (30321730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  HATTORI Nobutaka (80218510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  ARANO Taku (80750091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  ISHIHAMA Yasushi (30439244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUNAYAMA Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  佐藤 栄人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  高木 淳一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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