YAMAMOTO Akira 山本章

Researcher Number	00028408
Affiliation (based on the past Project Information) *help	1989 – 1995: NCVC, Vice Director, 副所長 1993: 国立循環器病センター, 研究所, 副所長 1991 – 1992: 国立循環器病センター研究所, 病因部, 部長 1990: 国立循環器病センター, 研究所, 副所長 1986 – 1988: 国立循環器病センター研究所, 病因部, 部長 … More 1987: 国立循環器病センター, 研究所・病因部, 部長 1986: National Cardiovascular Center Research Institute, 研究所病因部, 部長 1986: 循病セ, その他, 研究員 1985: 国立循環器病センター, その他, 研究員 Less
Review Section/Research Field	Principal Investigator 内分泌・代謝学 Except Principal Investigator Human genetics / 内分泌・代謝学 / 代謝生物化学 / Pathological medical chemistry
Keywords	Principal Investigator リポ蛋白リパーゼ / 血漿リポ蛋白 / Lipoprotein lipase / Cholesterol / Atherosclerosis / 粥状動脈硬化 / マクロファージ / トリグリセライド / 家族性高コレステロール血症 / Familial hypercholesterolemia … More / Apolipoprotein E / LDL receptor / Hyperlipidemia / Plasma lipoprotein / 虚血性心疾患 / 動脈硬化 / アポリポ蛋白E5とE7 / 低密度リポ蛋白レセプター(LDLレセプター) / 家族性高コンステロール血症 / リポタンパク質リパ-ゼ / 〓状動脈硬化 / コレステロ-ル / 家族性高コレステロ-ル血症 / リポタンパク質リバ-ゼ / アポリポタンパク質E / LDLレセプタ- / 高脂血症 / 血漿リポタンパク質 / Apolipoproteins / Hepatic lipase / LDL-receptor / Triglyceride / Hyperlipoproteinemia / アポリポ蛋白 / 肝トリグリセライドリパーゼ / LDL-レセプター / コレステロール / 血漿リポ蛋白代謝 / ヘパリン静注後血漿リパーゼ活性 / カイロマイクロン / I型高リポ蛋白血症 / コレステロール代謝 / 本態性高脂血症 / 低密度リポ蛋白(LDL)受容体 … More Except Principal Investigator 家族性高コレステロール血症 / Apolipoprotein / アポリポタンパク質 / リポ蛋白リパーゼ / LDLレセプター遺伝子 / Hypertriglyceridemia / Lipoprotein lipase / 高トリグリセリド血症 / Pyrene Compound / Lipid Microemulsion / Discoidal Highdensity Plasma Lipoprotein / Cholesterol Reverse Transport System / 脂質人工粒子 / ピレン-標識脂質 / 脂質転送蛋白質 / ディスコイダルHDL / コレステロール逆転送系 / Hyperlipidemia / Macrophage / 高脂血症 / レセプターの生合成 / 細胞膜蛋白質 / 遺伝子変異 / スプライシング異常 / 低比重リポ蛋白質 / リポ蛋白リパ-ゼ / リポ蛋白 / 低分子量G蛋白質 / 血管内皮由来弛緩因子 / 血管平滑筋 / 血管内皮 / lipoprotein / lipid transfer protein / cholesteryl ester transfer reaction / cholesteryl ester / リポタンパク質 / 脂質転送タンパク質 / コレステリルエステル転送反応 / コレステリルエステル / Transforming growth factor-beta1 / Scavenger receptor / Low-density lipoprotein / Cholesterol / Atherosclerosis / 泡沫化 / THP-1細胞 / PAI-1 / TGF-β1 / サイトカイン / TGF-β / スカベンジャー受容体 / マクロファージ / LDL / コレステロール / 動脈硬化 / アポリポ蛋白 / High density lipoprotein / Lipid transfer protein / Hepatic triglyceride lipase / Low density lipoprotein / 遺伝子解析 / 動脈硬化症 / 脂質転送蛋白 / 肝性トリグリセリドリパーゼ / Haplotype / Polymorphism / Direct sequencing / Heterozygote / Type IV hyperlipoproteinemia / ハプロタイプ / ポリモルフィズム / 直接塩基配列決定法 / ヘテロ接合体 / IV型高脂血症 / Cholesterol efflux / Vascular smooth muscle cell / コレステロール引き出し / 血管平滑筋細胞 / マウス腹腔マクロファ-ジ / ディスコイダル HDL / アポリポタンパクA / ピレン / 脂質転送蛋白質活性化因子 / コレステロ-ル逆転送系 / ピレンーコレステロ-ル / Endothelial Cell / cDNA Cloning / Enzyme Immunoassay / Lipoprotein Lipase / 免疫沈降 / リポ蛋白リパ-ゼ(LPL) / マクロファ-ジ / 内皮細胞 / cDNAクロ-ニング / 酵素免疫法 / ヒト遺伝病 / LDLセプター / 線維芽細胞 / 細胞内プロセシング / LDLレセプター / エンドセリンファミリー / ナトリウム利尿ペプチドファミリー / リゾフォスファチジルコリン / 胎児型ミオシン重鎖 / Rho / PD-ECGF / アクチビンA / NO / エンドセリン / CNP / common mutation / EGF前駆体相同ドメイン / アミノ酸置換 / 点変異 / エンドセリンファミリ- / ナトリウム利尿ペプチドファミリ- Less

Research Projects
(18 results)
Co-Researchers
(20 People)

Studies on the regulation of cholesteryl ester synthesis and mechanism of lipid accumulation in macrophage cells
- Principal Investigator
  
  YAMAMURA Taku, 斯波真理子
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of an underlying etiology of atherogenic type IV hyperlipoproteinemia and development of its genetic diagnostic method
- Principal Investigator
  
  TAKAGI Atsuko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
Molecular biological studies on the formation of atherogenic small dense low density lipoprotein (sLDL)
- Principal Investigator
  
  IKEDA Yasuyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
血管機能における神経・体液性因子の相関・病態
- Principal Investigator
  
  北徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ヒトLDL(低比重リポ蛋白質)レセプターの突然変異における遺伝子解析
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
Reaction mechanism of cholesterol transport system
- Principal Investigator
  
  ICHIKAWA Yoshiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagawa Medical School
MOLECULAR-GENETIC STUDY OF FAMILIAR HYPERLIPOPROTEINEMIA RELATED TO ATHEROSCLEROSISPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
家族性高コレステロール血症の原因遺伝子に解析
- Principal Investigator
  
  MIYAKE Yasuko
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
家族性高コレステロール血症の原因遺伝子の解析
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
血管機能における神経・体液性因子の相関・病態
- Principal Investigator
  
  井村裕夫
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Kinetics of cholesterol reverse transport system
- Principal Investigator
  
  ICHIKAWA Yoshiyuki, OHNISHI Taira
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagawa Medical School
Molecular Biological Study on Regulation and Expression of Physiological Function of Human Lipoprotein Lipase
- Principal Investigator
  
  IKEDA Yasuyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  National Cardiovascular Center Research Institute
ヒトLDL(低比重リポ蛋白)レセプターの突然変異における遺伝子解析
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
本態性高脂血症の成因,特に脂質水解酵素と関連因子の変異に関する分子遺伝学的研究Principal Investigator
- Principal Investigator
  
  山本章
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  National Cardiovascular Center Research Institute
ヒトLDL(低比重リポ蛋白)受容体の突然変異に関する研究
- Principal Investigator
  
  三宅康子
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Cardiovascular Center Research Institute
Molecular Basis of the Etiology and Pathogenesis of HyperlipoproteinemiaPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute (NCVC)
本態性高脂血症におけるアポリポ蛋白およびその受容体変異に関する分子遺伝学的研究Principal Investigator
- Principal Investigator
  
  山本章
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  National Cardiovascular Center Research Institute
Physiological roles of non-polar lipid transfer reaction between plasma lipoproteins and the reaction mechanism of its catalyst protein.
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  National Cardiovascular Center

1. YAMAMURA Taku (20132938)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
2. MIYAKE Yasuko (00132936)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. IKEDA Yasuyuki (90176107)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. YOKOYAMA Shinji (10142192)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. TAKAGI Atsuko (90179416)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. ICHIKAWA Yoshiyuki (60028355)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. OHNISHI Taira (50211107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TAKAICHI Shigeko (00093930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. TAJIMA Shoji (50132931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 北徹 (60161460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 高井義美 (60093514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 河合忠一 (70025659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KAWAGUCHI Akito (70214608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 井村裕夫 (10025570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 杉本恒明 (60019883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 猿田享男 (70051571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 泰江弘文 (40174502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 斯波真理子 (70271575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SIGANO Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 原斉

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAMOTO Akira 山本 章

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本態性高脂血症の成因,特に脂質水解酵素と関連因子の変異に関する分子遺伝学的研究Principal Investigator

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Molecular Basis of the Etiology and Pathogenesis of HyperlipoproteinemiaPrincipal Investigator

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本態性高脂血症におけるアポリポ蛋白およびその受容体変異に関する分子遺伝学的研究Principal Investigator

YAMAMOTO Akira 山本章