SHIKATA Kenichi 四方賢一

… Alternative Names

Researcher Number	00243452
Other IDs
Affiliation (Current)	2021: 岡山大学, 大学病院, 教授
Affiliation (based on the past Project Information) *help	2020: 岡山大学, 大学病院, 教授 2011 – 2018: 岡山大学, 大学病院, 教授 2011: 岡山大学, 岡山大学病院, 教授 2010 – 2011: 岡山大学, 医学部, 教授 2010: 岡山大学, 病院, 教授 … More
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Kidney internal medicine / 内科学一般 / Kidney internal medicine / Clinical nursing / Laboratory medicine / Community health/Gerontological nurisng / 内分泌・代謝学 / Periodontal dentistry / Basic Section 53040:Nephrology-related / Basic Section 90140:Medical technology assessment-related
Keywords	Principal Investigator 糖尿病性腎症 / ICAM-1 / 炎症 / マクロファージ / 接着分子 / 糖尿病 / サイトカイン / cholecystokinin / TGF-β / ノックアウトマウス … More Except Principal Investigator 糖尿病性腎症 / 糖尿病 / 腎臓 / collectrin / 糸球体 / Tim44 / kidney / extracellular matrix / マクロファージ / 基底膜 / 電子顕微鏡 / ネフローゼ症候群 / タンパク尿 / ミトコンドリア / 活性酸素 / 患者教育 / 教育プログラム / 細胞外マトリックス / 遺伝子 / gene / diabetes mellitus / 慢性関節リウマチ / T細胞 / インターフェロン-γ / 変形性関節症 / rheumatoid arthritis / macrophages / T cells / AGE / ICAM-1 / 糸球体硬化 / glomerulosclerosis / TNF-α / UCP-1 / Mn-SOD / ACE2 / HNF-1β / tissue negative staining / 酸化LDL / β2-グリコプロテインI(β2GPI) / C-反応性タンパク質(CRP) / 動脈硬化 / 感染免疫 / 抗リン脂質抗体症候群(APS) / 脂質代謝異常 / 複合体 / β_2-グリコプロテインI(β_2GPI) / 糖尿病慢性血管合併症 / tim44 / 地域での患者教育 / 腎症教室 / 多施設共同 / 糖尿病性腎症患者 / サポートシステム / 開業医 / 教育サポートシステム / 糖尿病予備軍 / ライフスタイル / 治療負担 / 予備軍 / 治療負担感 / 健康状態 / 糖尿病患者 / 糸球体基底膜 / 微細構造 / インテグリン / メサンギウム / 接着分子 / Tissue negative staining / ネフローゼトンネル / 糖尿病性腎炎 / Tissue Negative Staining / コラーゲン / glomerular basement membrane / ultrafine structure / electron microscope / integrin / mesangium / 細胞外基質 / IV型コラーゲン / プロテオグリカン / 免疫電顕 / 成長因子 / 形質交換 / 系球体 / glomerulus / type IV collagen / proteoglycans / immunoelectron microscopy / インターロイキン10 / インターロイキン4 / インターロイキン13 / 抗炎症性サイトカイン / 炎症性サイトカイン / 滑膜 / リウマトイド因子 / インターロイキン-10(IL-10) / 滑膜病変部 / RT-PCR法 / サイトカイン・ネットワーク / interleukin-10 / interleukin-4 / interleukin-13 / anti-inflammatory cytokine / inflammatory cytokine / メイラード反応 / 糖化反応最終産物 / 糖化反応 / メサンギウム細胞 / 血管合併症 / Maillard reaction / インターロイキン-12 / Thl細胞 / Th1型反応 / interferon-gamma / interleukin-12 / osteoarthritis / Th1 cells / 細胞接着分子 / セレクチン / スルファチド / 治療 / 腎炎 / 炎症 / 免疫 / 好中球 / Kidney / Adhesion molecule / Selectin / Glomerulonephritis / Diabetes / Sulfatide / Therapy / 糸球体過剰濾過 / DNAアレイ / CD-1マウス / 遺伝子クローニング / 遺伝子発現プロファイル / diabetic nephropathy / glomerular hyperfiltration / DNA array / CD-1 mouse / molecular cloning / gene expression profiling / 2型糖尿病 / 肥満 / インスリン抵抗性 / 歯周炎 / 1型糖尿病 / 血清診断 / GAD抗体 / 生活習慣病 / 歯周病 / 疑陽性 / type 2 diabetes / obesity / insulin resistance / periodontitis / type 1 diabetes / sero-diagnosis / GAD antibody / 遺伝子治療 / Diabetic nephropathy / ROS / Mitochondria / Gene therapy / 腎発生 / renal organogenesis / ACE遺伝子ファミリー / 高血圧 / 腎集合管細胞 / 賢集合管細胞 / ACE gene family / hypertension / renal collecting duct cells / 教育プロギラム / 糖尿病腎症 / パス解析 / 看護介入 / 対処行動 / 不確かさ / diabetic nephropathv / patient's education / education program / 先進医療 / 特定臨床研究 / データマネジメント Less

Development of the new therapeutic strategy for diabetic nephropathy by modulation of inflammasome.Principal InvestigatorOngoing
- Principal Investigator
  
  四方賢一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Okayama University
Quality management of Advanced medical care clinical resarch under Clinical Trial Act for pharmaceutial approval applicationOngoing
- Principal Investigator
  
  櫻井淳
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Okayama University
3次元マルチオミックス解析による糖尿病性腎症の新規治療標的の探索と同定Ongoing
- Principal Investigator
  
  宮本聡
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Okayama University
糖尿病性腎症に対する新規治療薬の開発～インフラマソームを標的とした探索的研究～Principal InvestigatorOngoing
- Principal Investigator
  
  四方賢一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Influences of Lifestyles on Health Conditions of Diabetic Patients and of Those Who Are Likely to Get Diabetic
- Principal Investigator
  
  Sumiyoshi Kazuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical nursing
- Research Institution
  Okayama Prefectural University
Investigation of the novel therapeutic targets for diabetic nephropathy.Principal Investigator
- Principal Investigator
  
  Shikata Kenichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Present challenges of regional training support systems for diabeticnephropathy patients
- Principal Investigator
  
  SUMIYOSHI Kazuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Okayama Prefectural University
  University of Hyogo
Development of the novel therapeutic strategy for diabetic nephropathy through anti-inflammatory effects.Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Exploratory research to development of novel therapeutic strategy for diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
New therapeutic approach to diabetic nephropathy by modulating mitochondrial function
- Principal Investigator
  
  MAKINO Hirofumi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Novel therapeutic targets for diabetic nephropathy.Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Identification of Interacting Molecules with Collectrin and their roles in Hypertension
- Principal Investigator
  
  WADA Jun
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Effects of uncertainty and coping on dietary behaviors in patients with diabetic nephropathy: Development of a model to predict dietary behavior.
- Principal Investigator
  
  ICHIMURA Mituko, 住吉和子
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical nursing
- Research Institution
  Okayama University
  Kawasaki University of Medical Welfare
"タンパク質"修飾酸化LDLの診断法の確立と動脈硬化における意義に関する研究
- Principal Investigator
  
  松浦栄次
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
Role of Macrophage in the pathogenesis of diabetic nephropathy and novel therapeutic target.Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  OKAYAMA UNIVERSITY
Reactive oxygen species and diabetic nephropathy
- Principal Investigator
  
  MAKINO Hirofumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  OKAYAMA UNIVERSITY
Identification of Novel ACE2 homologue, collectrin, and its role in renal organogenesis and progressive renal failure.
- Principal Investigator
  
  WADA Jun
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  OKAYAMA UNIVERSITY
Role of Macrophage in the pathogenesis of diabetic nephropathy revealed by ICAM-1 deficient mice.Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  OKAYAMA UNIVERSITY
A study on the establishment of periodontal treatment for patients with insulin resistant diabetes mellitus.
- Principal Investigator
  
  MURAYAMA Yoji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Molecular mechanism of glomerular hyperfiltration in diabetic nephropathy revealed by gene expression profiling.
- Principal Investigator
  
  MAKINO Hirofumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  OKAYAMA UNIVERSITY
Application of anti-adhesion molecule therapy for glomerulonephritis -Effects of sulfated oligosaccharides as selectin-blocking agents-Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Expression of interleukin-12 in synovial tissue from patients with rheumatoid arthritis.
- Principal Investigator
  
  YAMAMURA Masahiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Okayama University
Application of anti-cell adhesion molecule therapies for renal diseases.Principal Investigator
- Principal Investigator
  
  MAKINO Hirofumi, 四方賢一
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
糖尿病性腎症における糸球体細胞外マトリックスの分子構築の変化
- Principal Investigator
  
  OTA Zensuke
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Role of advanced glycation end-product in the development and progression of diabetic nephropathy.
- Principal Investigator
  
  MAKINO Hirofumi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Expression of interleukin-19 in synovial tissue from patients with rheumatoid arthritis
- Principal Investigator
  
  YAMAMURA Masahiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Okayama University
Mechanism of inflammatory cell infiltration in the kidney tissue of glomerulonephritis and diabetic nephropathy. -Elucidation of the role of cell adhesion molecules and development of therapeutic drugs.-Principal Investigator
- Principal Investigator
  
  SHIKATA Kenichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Okayama University
Molecular architecture and gene expression of glomerular extracellular matrix.
- Principal Investigator
  
  OTA Zensuke
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  Okayama University
Molecular biological approach to the abnormalities of extracelluar matrix of the diabetic nephropathy.
- Principal Investigator
  
  MAKINO Hirofumi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Okayama University

[Book] 慢性合併症の臨床2(腎症) 1.腎症の成因.糖尿病学の進歩2010
- Author(s)
  四方賢一、槇野博史
- Publisher
  日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21591031
[Book] 糖尿病学の進歩20102010
- Author(s)
  四方賢一、槇野博史
- Total Pages
  345
- Publisher
  診断と治療
- Data Source
  KAKENHI-PROJECT-21591031
[Book] 糖尿病最新の治療2010
- Author(s)
  四方賢一
- Total Pages
  310
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591031
[Book] 腎不全期糖尿病最新の治療2010
- Author(s)
  四方賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591031
[Book] フジメディカル社2008
- Author(s)
  四方賢一
- Publisher
  慢性腎臓病(CKD)とアディポネクチン. アディポネクチンとその受容体
- Data Source
  KAKENHI-PROJECT-19590952
[Book] 分子糖尿病学の進歩2008
- Author(s)
  四方賢一
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-19590952
[Book] 慢性腎臓病(CKD)からみた糖尿病性腎症. 分子糖尿病学の進歩2008
- Author(s)
  四方賢一
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-19590952
[Book] 代謝異常に伴う腎疾患. 糖尿病性腎症. 病気から見た治療戦略. 最新の治療2007
- Author(s)
  四方賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19590952
[Book] 糖尿病性腎症の成因とMicroinflammaton.糖尿病学の進歩(41集)2007
- Author(s)
  四方賢一
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] 糖尿病患者の「治療に伴うストレス認知尺度」の開発2017
- Author(s)
  住吉和子, 川田智恵子, 岡本辰夫, 大橋睦子, 實金　栄, 高林範子, 太湯好子, 金　外淑, 和田　淳, 四方賢一, 中嶋和夫
- Journal Title
  
  岡山医学会誌
  
  Volume: 印刷中
- NAID
  130006039367
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26463317
[Journal Article] Factors associated with remission and/or regression of microalbuminuria in type 2 diabetes mellitus.2014
- Author(s)
  Ono T, Shikata K, Obika M, Miyatake N, Kodera R, Hirota D, Wada J, Kataoka H, Ogawa D, Makino H
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 68 Pages: 235-241
- NAID
  120005465586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461224
[Journal Article] Lifestyle modification is associated with improving estimated glomerular filtration rate (eGFR) and proteinuria in Japanese with proteinuria.2014
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Acta Med Okayama
  
  Volume: 68 Pages: 43-46
- NAID
  120005372645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461224
[Journal Article] High glucose increases metallothionein expression in renal proximal tubular epithelial cells2012
- Author(s)
  Ogawa D, Asanuma M, Miyazaki I, Tachibana H, Wada J, Sogawa N, Sugaya T, Kitamura S, Maeshima Y, Shikata K, Makino H
- Journal Title
  
  Exp Diabetes Res
  
  Pages: 534872-534872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Cholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophage : anti-inflammatory effect of cholecystokinin2012
- Author(s)
  Miyamoto S, Shikata K, Miyasaka K, Okada S, Sasaki M, Kodera R, Hirota D, Kajitani N, Takatsuka T, Kataoka HU, Nishishita S, Sato C, Funakoshi A, Nishimori H, Uchida HA, Ogawa D, Makino H
- Journal Title
  
  Diabetes
  
  Volume: 61 Pages: 897-907
- NAID
  40019575963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] 糖尿病性腎症患者の地域での教育サポートシステム構築に関する現状と課題2012
- Author(s)
  住吉和子、川田智恵子、金外淑、松田佳美、四方賢一、山下眞宏
- Journal Title
  
  岡山県立大学保健福祉学部紀要
  
  Volume: Vol.19(1) Pages: 101-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592606
[Journal Article] Comparison of ventilatory threshold between subjects with and without proteinuria in Japanese2011
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Health
  
  Volume: 3 Pages: 394-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] The relation between estimated glomerular filtration rate(eGFR) and coffee consumption in the Japanese2011
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Health
  
  Volume: 3 Pages: 549-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Renoprotective effects of clarithromycin via reduction of urinary MCP-1 levels in type 2 diabetic patients2011
- Author(s)
  Tone A, Shikata K, Nakagawa K, Hashimoto M, Makino H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 79-85
- NAID
  10029004515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Comparison of muscle strength between subjects with and without proteinuria2011
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Health
  
  Volume: 3 Pages: 698-702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Decreasing serum uric acid levels might be associated with improving estimated glomerular filtration rate(eGFR) in Japanese men2011
- Author(s)
  Miyatake N, Shikata K, Makno H, Numata T
- Journal Title
  
  Health
  
  Volume: 3 Pages: 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes.2011
- Author(s)
  Kodera R, Shikata K, Kataoka HU, Takatsuka T, Miyamoto S, Sasaki M, Kajitani N, Nishishita S, Sarai K, Hirota D, Sato C, Ogawa D, Makino H.
- Journal Title
  
  Diabetologia
  
  Volume: 54 Pages: 965-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article]2011
- Author(s)
  Sato C, Shikata K, Hirota D, Sasaki M, Nishishita S, Miyamoto S, Kodera R, Ogawa D, Tone A, Kataoka HU, Wada J, Kajitani N, Makino H
- Journal Title
  
  Diabetes
  
  Volume: 60 Pages: 189-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Activation of peroxisome proliferator-activated receptor delta inhibits streptozotocin-induced diabetic nephropathy through anti-inflammatory mechanisms in mice.2011
- Author(s)
  Matsushita Y, Ogawa D, Wada J, Yamamoto N, Shikata K, Sato C, Tachibana H, Toyota N, Makino H.
- Journal Title
  
  Diabetes
  
  Volume: 60 Pages: 950-958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Intercellular adhesion molecule-1 plays a critical role in glomerulosclerosis after subtotal nephrectomy2011
- Author(s)
  Kido Y, Ogawa D, Shikata K, Sasaki M, Nagase R, Okada S, Usui Kataoka HU, Wada J, Makino H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 212-219
- NAID
  10029005164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Comparison of insulin detemir and insulin glargine on glycemic variability in patients with type 1 and type 2 diabetes2011
- Author(s)
  Tone A, Iseda I, Higuchi C, Tsukamoto K, Katayama A, Matsushita Y, Hida K, Wada J, Shikata K
- Journal Title
  
  Exp Clin Endocrinol Diabetes
  
  Volume: 118 Pages: 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Activation of peroxisome proliferator-activated receptor delta inhibits streptozotocin-induced diabetic nephropathy through anti-inflammatory mechanisms in mice2011
- Author(s)
  Matsushita Y, Ogawa D, Wada J, Yamamoto N, Shikata K, Sato C, Tachibana H, Toyota N, Makino H
- Journal Title
  
  Diabetes
  
  Volume: 60 Pages: 960-968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes2011
- Author(s)
  Kodera R, Shikata K, Kataoka HU, Takatsuka T, Miyamoto S, Sasaki M, Kajitani N, Nishishita S, Sarai K, Hirota D, Sato C, Ogawa D, Makino H
- Journal Title
  
  Diabetologia
  
  Volume: 54 Pages: 965-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] The Relation between estimated glomerular filtration rate(eGFR) and proteinuria in Okayama prefecture, Japan2011
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 16 Pages: 191-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Diabetic Nephropathy Remission and Regression Team Trial in Japan(DNETT-Japan) : Rationale and study design.2010
- Author(s)
  Shikata K, Haneda M, Koya D, Suzuki Y, Tomino Y, Yamada K, Maeda S, Kawakami N, Uzu T, Nishimura M, Sato C, Oqawa D.
- Journal Title
  
  Diabetes Res Clin Pract. 87
  
  Pages: 228-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] DNETT-Japan Study Group. Diabetic Nephropathy Remission and Regression Team Trial in Japan(DNETT-Japan): Rationale and study design2010
- Author(s)
  Shikata K, Haneda M, Koya D, Suzuki Y, Tomino Y, Yamada K, Maeda S, Kawakami N, Uzu T, Nishimura M, Sato C, Ogawa D, Makino H
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 87(2) Pages: 228-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Microinflammation is a common risk factor for progression of nephropathy and atherosclerosis in Japanese patients with type 2 diabetes2010
- Author(s)
  Kajitani N, Shikata K, Nakamura A, Nakatou T, Hiramatsu M, Makino H
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 88 Pages: 171-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Relationship between estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese.2010
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Acta Mad Okayama
  
  Volume: 84 Pages: 202-208
- NAID
  120002311048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Relation between estimated glomerular filtration rate and pulse wave velocity in Japanese2010
- Author(s)
  Miyatake N, Shikata K, Makino H, Numata T
- Journal Title
  
  Intern Med
  
  Volume: 49 Pages: 1315-1320
- NAID
  130000299533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Endothelial barrier protection of FTY720 under hyperglycemic condition : Involvement of focal adhesion kinase, small GTPases and adherens junction proteins2009
- Author(s)
  Sarai K, Shikata K, Shikata Y, Omori K, Watanabe N, Sasaki M, Nishishita S, Wada J, Goda N, Kataoka N, Makino H
- Journal Title
  
  Am J Physiol Cell Physiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Low-Protein Diet Study Group. Long-term effect of modification of dietary protein intake on the p progression of diabetic nephropathy : a randomised controlled trial2009
- Author(s)
  Koya D, Haneda M, Inomata S, Suzuki Y, Suzuki D, Makino H, Shikata K, Murakami Y, Tomino Y, Yamada K, Araki SI, Kashiwagi A, Kikkawa R
- Journal Title
  
  Diabetologia
  
  Volume: 52 Pages: 2037-2045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther. 330
  
  Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Endothelial barrier protection by FTY720 under hyperglycemic condition : involvement of focal adhesion kinase, small GTPases, and adherens junction proteins.2009
- Author(s)
  Sarai K, Shikata K, Shikata Y, Omori K, Watanabe N, Sasaki M, Nishishita S, Wada J, Goda N, Kataoka N, Makino H.
- Journal Title
  
  Am J Physiol Cell Physiol. 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
- Journal Title
  
  Pharmacol Exp Ther 20(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] 糖尿病性腎症2008
- Author(s)
  四方賢一, 槇野博史
- Journal Title
  
  腎と透析 64
  
  Pages: 945-950
- NAID
  10013354331
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] 糖尿病性腎症の画像診断2008
- Author(s)
  佐々木基史, 四方賢一
- Journal Title
  
  Diabetes Frontier 19
  
  Pages: 729-731
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] 糖尿病性腎症の治療におけるMicroinflammation制御の意義2008
- Author(s)
  四方賢一
- Journal Title
  
  BioClinica 23
  
  Pages: 52-56
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] 糖尿病性腎症2008
- Author(s)
  四方賢一
- Journal Title
  
  腎と透析 64
  
  Pages: 945-950
- NAID
  10013354331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin II--angiotensin II induces MCP-2 through AT1-receptor2007
- Author(s)
  Tone A, Shikata K, Ogawa D, Sasaki S, Nagase R, Sasaki M, Yozai K, Usui HK, Okada S, Wada J, Shikata Y, Makino H
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst 8
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin Angiotensin II induces MCP-2 through AT1-recentor2007
- Author(s)
  Tone, A., Shikata, K., Ogawa, D., Sasaki, S., Nagase, R., Sasaki, M., Yozai, K., Usui, HK., Okada, S., Wada, J., Shikata, Y., Makino, H
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst 8
  
  Pages: 45-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells2007
- Author(s)
  Omori, K., Shikata, Y., Sarai, K., Watanabe, N., Wada, J., Goda, N., Kataoka, N., Shikata, K., Makino, H
- Journal Title
  
  Am J Physiol Cell Physiol 293(5)
  
  Pages: 1523-1531
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-・B activation2007
- Author(s)
  Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H
- Journal Title
  
  Am J Physiol Renal Physiol 292
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H
- Journal Title
  
  Diabetes 56
  
  Pages: 363-372
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients.2007
- Author(s)
  Yoshikawa R, Wada J, Seiki K, Matsuoka T, Miyamoto S, Takahashi K, Ota S, Taniai K, Hida K, Yamakado M, Shikata K, Uehara Y, Urade Y, Makino H.
- Journal Title
  
  Diabetes Res Clin Pract. 76・3
  
  Pages: 358-367
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-KB activation2007
- Author(s)
  Ohga, S., Shikata, K., Yozai, K., Okada, S., Ogawa, D., Usui, H., Wada, J., Shikata, Y., Makino, H
- Journal Title
  
  Am J Physiol Renal Physiol 292
  
  Pages: 1141-1150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-κB a ctivation.2007
- Author(s)
  Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H
- Journal Title
  
  Am J Physiol Renal Physiol 292
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Changes of gene expression profiles in macrophages stimulated by an giotensin II Angiotensin II induces MCP-2 through AT 1-receptor.2007
- Author(s)
  Tone A, Shikata K, Ogawa D, Sasaki S, Nagase R, Sasaki M, Yozai K, Usui HK, Okada S, Wada J, Shikata Y, Makino H
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst 8
  
  Pages: 45-50
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis.2007
- Author(s)
  Tabuchi M, Inoue K, Usui-Kataoka H, Kobayashi K, Teramoto M, Takasugi K, Shikata K, Yamamura M, Ando K, Nishida K, Kasahara J, Kume N, Lopez LR, Mitsudo K, Nobuyoshi M, Yasuda T, Kita T, Makino H, Matsuura E.
- Journal Title
  
  J Lipid Res. 48・4
  
  Pages: 768-781
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Effects of uncertainty and coping on dietary behaviors in patients with diabetic nephropathy: Development of a model to predict dietary behavior.2007
- Author(s)
  Kazuko SUMIYOSHI, Chieko KAWATA, Kenichi SHIKATA, Hirofumi MAKINO
- Journal Title
  
  Diabetes Educator 投稿中
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17592245
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin II Angiotensin II induces MCP-2 through AT1-receptor.2007
- Author(s)
  Tone A, Shikata K, et. al.
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst 8
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin II-angiotensin II induces MCP-2 through AT1-receptor2007
- Author(s)
  Tone, A., Shikata, K., Ogawa, D., Sasaki, S., Nagase, R., Sasaki, M., Yozai, K., Usui, HK., Okada, S., Wada, J., Shikata, Y., Makino, H
- Journal Title
  
  J Renin Angiotensin Aldosterone 8(1)
  
  Pages: 45-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Macrophage scavenger receptor-α-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H
- Journal Title
  
  Diabetes 56
  
  Pages: 363-372
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Macrophage scavenger receptor-・-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, et. al.
- Journal Title
  
  Diabetes 56
  
  Pages: 363-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H
- Journal Title
  
  Diabetes 56
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation.2007
- Author(s)
  Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H.
- Journal Title
  
  Am J Physiol Renal Physiol. 292・4
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin II-angiotensin II induces MCP-2 through AT1-receptor.2007
- Author(s)
  Tone A, Shikata K, Ogawa D, Sasaki S, Nagase R, Sasaki M, Yozai K, Usui HK, Okada S, Wada J, Shikata Y, Makino H.
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst. 8・1
  
  Pages: 45-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells2007
- Author(s)
  Omori K, Shikata Y, Sarai K, Watanabe N, Wada J, Goda N, Kataoka N, Shikata K, Makino H
- Journal Title
  
  Am J Physiol Cell Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1523-31.Epub2007Aug8.2007
- Author(s)
  Omori K, Shikata Y, Sarai K, Watanabe N, Wada J, Goda N, Kataoka N, Shikata K, Makino H.
- Journal Title
  
  Am J Physiol Cell Physiol. 263・5
  
  Pages: 1523-1531
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] 糖尿病性腎症の成因と新しい治療戦略2007
- Author(s)
  四方賢一
- Journal Title
  
  Medical View Point 28
  
  Pages: 10-10
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Macrophage scavenger receptor-A-deficient mice are resistant against diabetic nephropathy throuth amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H
- Journal Title
  
  Diabetes 56(2)
  
  Pages: 363-72
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] The association of C-reactive protein with an oxidative metabolite of LDL and its implicationin atherosclerosis2007
- Author(s)
  Tabuchi M, Inoue K, Usui-Kataoka H, Kobayashi K, Teramoto M, Takasugi K, Shikata K, Yamamura M, Ando K, Nishida K, Kasahara J, Kume N, Lopez LR, Mitsudo K, Nobuyoshi M, Yasuda T, Kita T, Makino H, Matsuura E
- Journal Title
  
  J Lipid Res 48
  
  Pages: 768-781
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis2007
- Author(s)
  Tabuchi, M., Inoue, K., Usui-Kataoka, H., Kobayashi, K., Teramoto, M., Takasugi, K., Shikata, K., Yamamura, M., Ando, K., Nishida, K., Kasahara, J., Kume, N., Lopez, LR., Mitsudo, K., Nobuyoshi, M., Yasuda, T., Kita, T., Makino, H., Matsuura, E
- Journal Title
  
  J Lipid Res 48(4)
  
  Pages: 768-781
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] 特集 : 糖尿病性腎症. 糖尿病性腎症の成因としてのMicroinflammation2007
- Author(s)
  四方賢一
- Journal Title
  
  日本腎臓学会誌 49
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-・B activation2007
- Author(s)
  Ohga S, Shikata K, et. al.
- Journal Title
  
  Am J Physiol Renal Physiol 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients2007
- Author(s)
  Yoshikawa, R., Wada, J., Seiki, K., Matsuoka, T., Miyamoto, S., Takahashi, K., Ota, S., Taniai, K., Hida, K., Yamakado, M., Shikata, K., Uehara, Y., Urade, Y., Makino, H
- Journal Title
  
  Diabetes Res Clin Pract 76(3)
  
  Pages: 358-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation2007
- Author(s)
  Ohga, S., Shikata, K., Yozai, K., Okada, S., Ogawa, D., Usui, H., Wada, J., Shikata, Y., Makino, H
- Journal Title
  
  Am J Physiol Renal Physiol 292(4)
  
  Pages: 1141-1150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells2007
- Author(s)
  Omori K, Shikata Y, Sarai K, Watanabe N, Wada J, Goda N, Kataoka N, Shikata K, Makino H
- Journal Title
  
  Am J Physiol Cell Physiol 293
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients.2007
- Author(s)
  Yoshikawa R, Wada J, Seiki K, Matsuoka T, Miyamoto S, Takahashi K, Ota S, Taniai K, Hida K, Yamakado M, Shikata K, Uehara Y, Urade Y, Makino H
- Journal Title
  
  Diabetes Res Clin Pract 76
  
  Pages: 358-367
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Urinary PGDS levels are associated with vascular iniury in type 2 diabetes patients2007
- Author(s)
  Yoshikawa, R., Wada, J., Seiki, K., Matsuoka, T., Miyamoto, S., Takahashi, K., Ota, S., Taniai, K., Hida, K., Yamakado, M., Shikata, K., Uehara, Y., Urade, Y., Makino, H
- Journal Title
  
  Diabetes Res Clin Pract 76
  
  Pages: 358-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients.2007
- Author(s)
  Yoshikawa R, Wada J, Seiki K, Matsuoka T, Miyamoto S, Takahashi K, Ota S, Taniai K, Hida K, Yamakado M, Shikata K, Uehara Y, Urade Y, Makino H.
- Journal Title
  
  Deabetes Res Clin Pract. 76
  
  Pages: 358-367
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H.
- Journal Title
  
  Diabetes 56・2
  
  Pages: 363-372
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Macrophage scavenger receptor-α-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation2007
- Author(s)
  Usui, HK., Shikata, K., Sasaki, M., Okada, S., Matsuda, M., Shikata, Y., Ogawa, D., Kido, Y., Nagase, R., Yozai, K., Ohga, S., Tone, A., Wada, J., Takeya, M., Horiuchi, S., Kodama, T., Makino, H
- Journal Title
  
  Diabetes 56
  
  Pages: 363-372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells.2007
- Author(s)
  Omori K, Shikata Y, Sarai K, Wa
- Journal Title
  
  Am J Physiol Cell Physiol 293
  
  Pages: 1523-1531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Changes of gene expression profiles in macrophages stimulated by angiotensin II Angiotensin II induces MCP-2 through AT1-receptor.2007
- Author(s)
  Tone A, Shikata K, et. al.
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst 8
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] 糖尿病性腎症-日本の研究から-2007
- Author(s)
  四方賢一、槇野博史
- Journal Title
  
  内科 100
  
  Pages: 74-78
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Macrophage scavenger receptor-A-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.2007
- Author(s)
  Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozaki K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H
- Journal Title
  
  Diabetes 56(2)
  
  Pages: 363-72
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation2007
- Author(s)
  Usui, HK., Shikata, K., Sasaki, M., Okada, S., Matsuda, M., Shikata, Y., Ogawa, D., Kido, Y., Nagase, R., Yozai, K., Ohga, S., Tone, A., Wada, J., Takeya, M., Horiuchi, S., Kodama, T., Makino, H
- Journal Title
  
  Diabetes 56(2)
  
  Pages: 363-372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis2007
- Author(s)
  Tabuchi M, Inoue K, Usui-Kataoka H, Kobayashi K, Teramoto M, Takasugi K, Shikata K, Yamamura M, Ando K, Nishida K, Kasahara J, Kume N, LopezMitsudo K, Nobuyoshi M, Yasuda T, Kita T, Makino H, Matsuura E
- Journal Title
  
  J Lipid Res 48
  
  Pages: 768-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590952
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by ingibition of NF-kB activation2007
- Author(s)
  Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H.
- Journal Title
  
  Am J Physiol Renal Physiol 2920
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinediones Ameliorate Diabetic Nephropathy via Cell Cycle-Dependent Mechanisms.2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H
- Journal Title
  
  Diabetes 55
  
  Pages: 1666-1677
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production.2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H
- Journal Title
  
  J Am Soc Nephrol 17
  
  Pages: 1090-1101
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-_kB activation.2006
- Author(s)
  Ohga S, Shikata K, Yozai K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H
- Journal Title
  
  Am J Physiol Renal Physiol [Epub ahead of print] (In press)
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms.2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H
- Journal Title
  
  Diabetes 55(6)
  
  Pages: 1666-1677
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Elevated serum MCP-4 levels in overweight subjects and its correlation with chronic inflammation2006
- Author(s)
  Hashimoto, I., Wada, J., Hida, A., Baba, M., Miyatake, N., Eguchi, J., Shikata, K., Makino, H
- Journal Title
  
  Obes Res 14(5)
  
  Pages: 799-811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects2006
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obesity (Silver Spring) 14
  
  Pages: 799-811
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-κB activation.2006
- Author(s)
  Ohga S, Shikata K, Yozaki K, Okada S, Ogawa D, Usui H, Wada J, Shikata Y, Makino H
- Journal Title
  
  Am J Physiol Renal Physiol [Epub ahead of print] (in press)
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms2006
- Author(s)
  Okada, T., Wada, J., Hida, K., Eguchi, J., Hashimoto, I., Baba, M., Yasuhara, A., Shikata, K., Makino, H
- Journal Title
  
  Diabetes 55(6)
  
  Pages: 1666-1677
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of Tim44 by reducing mitochondrial superoxide production2006
- Author(s)
  Zhang, Y., Wada, J., Hashimoto, I., Eguchi, J., Yasuhara, A., Kanwar, YS., Shikata, K., Makino, H
- Journal Title
  
  J Am Soc Nephrol 17(4)
  
  Pages: 1090-1101
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects2006
- Author(s)
  Hashimoto, I., Wada, J., Hida, A., Baba, M., Miyatake, N., Eguchi, J., Shikata, K., Makino, H
- Journal Title
  
  Obesity (Silver Spring) 14(5)
  
  Pages: 799-811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] The precision of the measurement of hemoglobinAic with POCT in hygienic guidance of diabetic patients2006
- Author(s)
  Mituko, ichimura, Kazuko, Sumiyoshi, Shinich, Usui, Misako, Shibakura, Hiroko, Touge, Satishi, Ikeda, Kenichi, Shikata
- Journal Title
  
  Japanese Journal of medical technology 55(1)
  
  Pages: 41-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Journal Article] Thiazolidinediones Ameliorate Diabetic Nephropathy via Cell Cycle-Dependent Mechanisms2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H
- Journal Title
  
  Diabetes 55
  
  Pages: 1666-1677
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H.
- Journal Title
  
  Diabetes.2006 Jun;55(6):1666-77 55・6
  
  Pages: 1666-1677
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinediones Ameliorate Diabetic Nephropathy via Cell Cycle-Dependent Mechanisms.2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H
- Journal Title
  
  Diabetes 55
  
  Pages: 1666-1677
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects.2006
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obesity (Selver Spring) 14
  
  Pages: 799-811
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] 糖尿病療養指導でのPOCTによるHbA1c測定の精度2006
- Author(s)
  一村光子, 住吉和子, 臼井真一, 柴倉美砂子, 唐下博子, 池田敏, 四方賢一
- Journal Title
  
  医学検査 55(1)
  
  Pages: 41-44
- NAID
  10020334667
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17592245
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of Tim44 by reducing mitochondrial superoxide production.2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H
- Journal Title
  
  J Am Soc Nephrol 17(4)
  
  Pages: 1090-1101
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Elevated serum MCP-4 levels in overweight subjects and its correlation with chronic inflammation.2006
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obes Res 14(5)
  
  Pages: 799-811
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients.2006
- Author(s)
  Yoshikawa R, Wada J, Seiki K, Matsuoka T, Miyamoto S, Takahashi K, Ota S, Taniai K, Hida K, Yamakado M, Shikata K, Uehara Y, Urade Y, Makino H
- Journal Title
  
  Diabetes Red Clin Pract [Epub ahead of print] (In press)
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Urinary PGDS levels are associated with vascular injury in type 2 diabetes patients.2006
- Author(s)
  Yoshikawa R, Wada J, Seki K, Matsuoka T, Miyamoto S, Takahashi K, Ota S, Taniai K, Hida K, Yamakado M, Shikata K, Uehara Y, Urade Y, Makino H
- Journal Title
  
  Diabetes Res Clin Pract [Epub ahead of print] (In press)
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Thiazolidinediones Ameliorate Diabetic Nephropathy via Cell Cycle-Dependent Mechanisms.2006
- Author(s)
  Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H.
- Journal Title
  
  Diabetes. 2006 Jun;55(6) : 1666-77 55
  
  Pages: 1666-1677
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms2006
- Author(s)
  Okada, T., Wada, J., Hida, K., Eguchi, J., Hashimoto, I., Baba, M., Yasuhara, A., Shikata, K., Makino, H
- Journal Title
  
  Diabetes 55(6)
  
  Pages: 1666-1677
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production.2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H.
- Journal Title
  
  J Am Soc Nephrol. 17
  
  Pages: 1090-1101
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Therapeutic approach for diabetic nephropathyusing gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production.2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H.
- Journal Title
  
  J Am Soc Nephrol. Apr. 17・4
  
  Pages: 1090-1101
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production.2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H
- Journal Title
  
  J Am Soc Nephrol 17
  
  Pages: 1090-1101
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects.2006
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H.
- Journal Title
  
  Obesity (Silver Spring) 14・5
  
  Pages: 799-811
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production2006
- Author(s)
  Zhang, Y., Wada, J., Hashimoto, I., Eguchi, J., Yasuhara, A., Kanwar, YS., Shikata, K., Makino, H
- Journal Title
  
  Am Soc Nephrol 17(4)
  
  Pages: 1090-1010
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects.2006
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obesity (Silver Spring) 14
  
  Pages: 799-811
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Therapeutic approach fodiabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production2006
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H
- Journal Title
  
  J Am Soc Nephrol 17
  
  Pages: 1090-1101
- Data Source
  KAKENHI-PROJECT-18390249
[Journal Article] Sulfated hyaluronic acid, a potential selectin inhibitor, ameliorates experimentally induced crescentic glomerulonephritis.2005
- Author(s)
  Ogawa D, Shikata K, Matsuda M, Akima K, Iwahashi M, Okada S, Tsuchiyama Y, Shikata Y, Wada J, Makino H
- Journal Title
  
  Nephron Exp Nephrol 99
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell cycle-dependent mechanisms.2005
- Author(s)
  Baba M, Wada J, Eguchi J, Hashimoto I, Okada T, Yasuhara A, Shikata k, Kanwar YS, Makino H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3222-3234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Sulfated hyaluronic acid, a potential selectin inhibitor, ameliorates experimentally induced crescentic glomerulonephritis.2005
- Author(s)
  Ogawa D, Shikata K, Matsuda M, Akima K, Iwahashi M, Okada S, Tsuchiyama Y, Shikata Y, Wada J, Makino H.
- Journal Title
  
  Nephron Exp Nephrol gg:e
  
  Pages: 26-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor : A unique insulin-sensitizing adipocytokine in obesity.2005
- Author(s)
  Hida K, Wada J, Eguchi J, Zhang H, Baba M, Seida A, Hashimoto I, Okada T, Yasuhara A, Nakatsuka A, Shikata K, Hourai S, Futami J, Watanabe E, Matsuki Y, Hiramatsu R, Akagi S, Makino H, Kanwar YS
- Journal Title
  
  Proc Natl Acad Sci U S A 102(30)
  
  Pages: 101610-101615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Sulfated hyaluronic acid, a potential selectin inhibitor, ameliorates experimentally induced crescentic glomerulonephritis.2005
- Author(s)
  Ogawa D, Shikata K, Matsuda M, Akima K, Iwahashi M, Okada S, Tsuchiyama Y, Shikata Y, Wada J, Makino H.
- Journal Title
  
  Nephron Exp Nephrol. 99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes.2005
- Author(s)
  Nakamura A, Shikata K, Hiramatsu M, Nakatou T, Kitamura T, Wada J, Itoshima T, Makino H.
- Journal Title
  
  Diabetes Care. 28;, 2005. 28
  
  Pages: 2890-2895
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Pathological roles of advanced glycation end product receptors SR-A and CD36.2005
- Author(s)
  Horiuchi S, Unno Y, Usui H, Shikata K, Takaki K, Koito W, Sakamoto Y, Nagai R, Makino K, Sasao A, Wada J, Makino H
- Journal Title
  
  Ann N Y Acad Sci 1043
  
  Pages: 671-675
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Clinical features of non-diabetic renal diseases in patients with type 2 diabetes.2005
- Author(s)
  Tone A, Shikata K, Matsuda M, Usui H, Okada S, Ogawa D, Wada J, Makino H
- Journal Title
  
  Diabetes Res Clin Pract 69(3)
  
  Pages: 237-242
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell-cycle-dependent mechanisms.2005
- Author(s)
  Baba M, Wada J, Eguchi J, Hashimoto I, Okada T, Yasuhara A, Shikata K, Kanwar YS, Makino H.
- Journal Title
  
  J. Am Soc Nephrol. 16
  
  Pages: 3222-3234
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.2005
- Author(s)
  Yozai K, Shikata K, Sasaki M, Tone A, Ohga S, Usui H, Okada S, Wada J, Nagse R, Ogawa D, Shikata Y, Makino H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3326-3338
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.2005
- Author(s)
  Eguchi J, Wada J, Hida K, Zhang H, Matsuoka T, Baba M, Hashimoto I, Shikata K, Ogawa N, Makino H.
- Journal Title
  
  Biochem J. 5
  
  Pages: 343-353
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell cycle-dependent mechanisms2005
- Author(s)
  Baba, M., Wada, J., Eguchi, J., Hashimoto, I., Okada, T., Yasuhara, A., Shikata, K., Kanwar, YS., Makino, H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3222-3234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats.2005
- Author(s)
  Matsuoka T, Wada J, Hashimoto I, Zhang Y, Eguchi J, Ogawa N, Shikata K, Kanwar YS, Makino H
- Journal Title
  
  Diabetes 54(10)
  
  Pages: 2882-2890
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.2005
- Author(s)
  Eguchi J, Wada J, Hida K, Zhang H, Matsuoka T, Baba M, Hashimoto I, Shikata K, Ogawa N, Makino H
- Journal Title
  
  Biochem J 387(2)
  
  Pages: 343-3541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Gene delivery of Tim-44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats.2005
- Author(s)
  Matsuoka T, Wada J, Hashimoto I, Zhang Y, Eguchi J, Ogawa N, Shikata K, Kanwar YS, Makino H
- Journal Title
  
  Diabetes 54(10)
  
  Pages: 2882-2890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity2005
- Author(s)
  Eguchi, J., Wada, J., Hida, K., Zhang, H., Matsuoka, T., Baba, M., Hashimoto, I., Shikata, K., Ogawa, N., Makino, H
- Journal Title
  
  Biochem 387(2)
  
  Pages: 343-3541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Sulfated hyaluronic acid, a potential selectin inhibitor, ameliorates experimentally induced crescentic glomerulonephritis.2005
- Author(s)
  Ogawa D, Shikata K, Matsuda M, Akima K, Iwahashi M, Okada S, Tsuchiyama Y, Shikata Y, Wada J, Makino H.
- Journal Title
  
  Nephron Exp Nephrol 99:e
  
  Pages: 26-32
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor : A unique insulin-sensitizing adipocytokine in obesity2005
- Author(s)
  Hida, K., Wada, J., Eguchi, J., Zhang, H., Baba, M., Seida, A., Hashimoto, I., Okada, T., Yasuhara, A., Nakatsuka, A., Shikata, K., Hourai, S., Futami, J., Watanabe, E., Matsuki, Y., Hiramatsu, R., Akagi, S., Makino, H., Kanwar, YS
- Journal Title
  
  Proc Natl Acad Sci U S A 102(30)
  
  Pages: 101610-10615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats2005
- Author(s)
  Tone, A., Shikata, K., Sasaki, M., Ohga, S., Yozai, K., Nishishita, S., Usui, H., Nagase, R., Ogawa, D., Okada, S., Shikata, Y., Wada, J., Makino, H
- Journal Title
  
  Diabetologia 48(11)
  
  Pages: 2402-2411
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Clinical features of non-diabetic renal diseases in patients with type 2 diabetes.2005
- Author(s)
  Tone A, Shikata K, Matsuda M, Usui H, Okada S, Ogawa D, Wada J, Makino H.
- Journal Title
  
  Diabetes Res pract. 69
  
  Pages: 237-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell-cycle-dependent mechanisms.2005
- Author(s)
  Baba M, Wada J, Eguchi J, Hashimoto I, Okada T, Yasuhara A, Shikata K, Kanwar YS, Makino H.
- Journal Title
  
  J Am Soc Nephrol. 16
  
  Pages: 3326-3338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice viacell cycle-dependent mechanisms.2005
- Author(s)
  Baba M, Wada J, Eguchi J, Hashimoto I, Okada T, Yasuhara A, Shikata K, Kanwar YS, Makino H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3222-3234
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Clinical features of non-diabetic renal diseases in patients with type 2 diabetes.2005
- Author(s)
  Tone A, Shikata K, Matsuda M, Usui H, Okada S, Ogawa D, Wada J, Makino H.
- Journal Title
  
  Diabetes Res Clin Pract. 69
  
  Pages: 237-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.2005
- Author(s)
  Tone A, Shikata K, Sasaki M, Ohga S, Yozai K, Nishishita S, Usui H, Nagase R, Ogawa D, Okada S, Shikata Y. Wada J, Makino H.
- Journal Title
  
  Diabetologia. 48
  
  Pages: 2402-2411
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor : a unique insulin-sensitizing adipocytokine in obesity.2005
- Author(s)
  Hida K, Wada J, Eguchi J, Zhang H, Baba M, Seida A, Hashimoto I, Okada T, Yasuhara A, Nakatsuka A, Shikata K, Hourai S, Futami J, Watanabe E, Matsuki Y, Hiramatsu R, Akagi S, Makino H, Kanwar YS.
- Journal Title
  
  Proc Natl Acad Sci USA 26
  
  Pages: 10610-10615
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions2005
- Author(s)
  Yozai, K., Shikata, K., Sasaki, M., Tone, A., Ohga, S., Usui, H., Okada, S., Wada, J., Nagse, R., Ogawa, D., Shikata, Y., Makino, H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3326-3338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Pathological roles of advanced glycation end product receptors SR-A and CD36.2005
- Author(s)
  Horiuchi S, Unno Y, Usui H, Shikata K, Takaki K, Koito W, Sakamoto Y, Nagai R, Makino K, Sasao A, Wada J, Makino H
- Journal Title
  
  Ann N Y Acad Sci. 1043
  
  Pages: 671-6752
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor : A unique insulin-sensitizing adipocytokine in obesity.2005
- Author(s)
  Hida K, Wada J, Eguchi J, Zhang H, Baba M, Seida A, Hashimoto I, Okada T, Yasuhara A, Nakatsuka A, Shikata K, Hourai S, Futami J, Watanabe E, Matsuki Y, Hiramatsu R, Akagi S, Makino H, Kanwar YS
- Journal Title
  
  Proc Natl Acad Sci U S A 102(30)
  
  Pages: 101610-10615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Journal Article] Pathological roles of advanced glycation end product receptors SR-A and CD36.2005
- Author(s)
  Horiuchi S, Unno Y, Ushi H, Shikata K, Takaki K, Koito W, Sakamoto Y, Nagai R, Makino K, Sasao A, Wada J, Makino H
- Journal Title
  
  Ann N Y Acad Sci. 1043
  
  Pages: 671-675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Sulfated hyaluronic acid, a potential selectin inhibitor, ameliorates experimentally induced crescentic glomerulonephritis2005
- Author(s)
  Ogawa, D., Shikata, K., Matsuda, M., Akima, K., Iwahashi, M., Okada, S., Tsuchiyama, Y., Shikata, Y., Wada, J., Makino, H
- Journal Title
  
  Nephron Exp Nephrol 99
  
  Pages: 26-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes.2005
- Author(s)
  Nakamura A, Shikata K, Hiramatsu M, Nakatou T, Kitamura T, Wada J, Itoshima T, Makino H.
- Journal Title
  
  Diabetes Care. 28
  
  Pages: 2890-2895
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Pathological roles of advanced glycation end product receptors SR-A and CD362005
- Author(s)
  Horiuchi, S., Unno, Y., Usui, H., Shikata, K., Takaki, K., Koito, W., Sakamoto, Y., Nagai, R., Makino, K., Sasao, A., Wada, J., Makino, H
- Journal Title
  
  Ann N Y Acad Sci 1043
  
  Pages: 671-675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.2005
- Author(s)
  Yozai K, Shikata K, Sasaki M, Tone A, Ohga S, Usui H, Okada S, Wada J, Nagase R, Ogawa D, Shikata Y, Makino H.
- Journal Title
  
  J Am Soc Nephrol. 16
  
  Pages: 3326-3338
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats.2005
- Author(s)
  Matsuoka T, Wada J, Hashimoto I, Zhang Y, Eguchi J, Ogawa N, Shikata K, Kanwar YS, Makino H
- Journal Title
  
  Diabetes 54(10)
  
  Pages: 2882-2890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Journal Article] Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.2005
- Author(s)
  Tone A, Shikata K, Sasaki M, Ohga S, Yozai K, Nishishita S, Usui H, Nagase R, Ogawa D, Okada S, Shikata Y, Wada J, Makino H.
- Journal Title
  
  Diabetologia. 48
  
  Pages: 2402-2411
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor : a unique insulin-sensitizing adipocytokine in obesity.2005
- Author(s)
  Hida K, Wada J, Eguchi J, Zhang H, Baba M, Seida A, Hashimoto I, Okada T, Yasuhara A, Nakatsuka A, Shikata K, Hourai S, Futami J, Watanabe E, Matsuki Y, Hiramatsu R, Akagi S, Makino H, Kanwar YS.
- Journal Title
  
  Proc Natl Acad Sci USA. 26
  
  Pages: 10610-10615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.2005
- Author(s)
  Eguchi J, Wada J, Hida K, Zhang H, Matsuoka T, Baba M, Hashimoto I, Shikata K, Ogawa N and Makino H
- Journal Title
  
  Biochem J 387(2)
  
  Pages: 343-3541
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell cycle-dependent mechanisms.2005
- Author(s)
  Baba M, Wada J, Eguchi J, Hashimoto I, Okada T, Yasuhara A, Shikata K, Kanwar YS, Makino H
- Journal Title
  
  J Am Soc Nephrol 16(11)
  
  Pages: 3222-3234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Journal Article] Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity.2005
- Author(s)
  Hida K, Wada J, Eguchi J, Zhang H, Baba M, Seida A, Hashimoto I, Okada T, Yasuhara A, Nakatsuka A, Shikata K, Hourai S, Futami J, Watanabe E, Matsuki Y, Hiramatsu R, Akagi S, Makino H, Kanwar YS
- Journal Title
  
  Proc Natl Acad Sci USA 102(30)
  
  Pages: 101610-10615
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.2005
- Author(s)
  Tone A, Shikata K, Sasaki M, Ohga S, Yozai K, Nishishita S, Usui H, Nagase R, Ogawa D, Okada S, Shikata Y, Wada J, Makino H
- Journal Title
  
  Diabetologia 48(11)
  
  Pages: 2402-2411
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Serum interleukin-18 levels are associated with nephropathy and atherosclerosisi in Japanese patients with type 2 diabetes.2005
- Author(s)
  Nakamura A, Shikata K, Hiram atsu M, Nakatou T, Kitamura T, Wada J, Itoshima T, Makino H
- Journal Title
  
  Diabetes Care 28(12)
  
  Pages: 2890-2805
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Clinical features of non-diabetic renal diseases in patients with type 2 diabetes2005
- Author(s)
  Tone, A., Shikata, K., Matsuda, M., Usui, H., Okada, S., Ogawa, D., Wada, J., Makino, H
- Journal Title
  
  Diabetes Res Clin Pract 69(3)
  
  Pages: 237-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.2005
- Author(s)
  Yozai K, Shikata K, Sasaki M, Tone A, Ohga S, Usui H, Okada S, Wada J, Nagase R, Ogawa D, Shikata Y, Makino H.
- Journal Title
  
  J Am Soc Nephrol. 16
  
  Pages: 3326-3338
- Data Source
  KAKENHI-PROJECT-17590828
[Journal Article] Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.2005
- Author(s)
  Tone A, Shikata K, Sasaki M, Ohga S, Yozaki K, Nishishita S, Usui H, Nagase R, Ogawa D, Okada S, Shikata Y, Wada J, Makino H.
- Journal Title
  
  Diabetologia. 48
  
  Pages: 2402-2411
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.2005
- Author(s)
  Eguchi J, Wada J, Hida K, Zhang H, Matsuoka T, Baba M, Hashimoto I, Shikata K, Ogawa N, Makino H
- Journal Title
  
  Biochem J 387(2)
  
  Pages: 343-3541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Journal Article] Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats2005
- Author(s)
  Matsuoka, T., Wada, J., Hashimoto, I., Zhang, Y., Eguchi, J., Ogawa, N., Shikata, K., Kanwar, YS., Makino, H
- Journal Title
  
  Diabetes 54(10)
  
  Pages: 2882-2890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] Serum interleulcin-18 levels are associated with nephropathy and atherosclerosisi in Japanese patients with type 2 diabetes2005
- Author(s)
  Nakamura, A., Shikata, K., Hiramatsu, M., Nakatou, T., Kitamura, T., Wada, J., Itoshima, T., Makino, H
- Journal Title
  
  Diabetes Care 28(12)
  
  Pages: 2890-2805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590829
[Journal Article] The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.2004
- Author(s)
  Hiragushi K, Wada J, Eguchi J, Matsuoka T, Yasuhara A, Hashimoto I, Yamashita T, Hida K, Nakamura Y, Shikata K, Minamino N, Kangawa K, Makino H.
- Journal Title
  
  Kdney Int. 65
  
  Pages: 540-550
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.2004
- Author(s)
  Hiragushi K, Wada J, Eguchi J, Matsuoka T, Yasuhara A, Hashimoto I, Yamashita T, Hida K, Nakamura Y, Shikata K, Minamino N, Kangawa K, Makino H.
- Journal Title
  
  Kidney Int. 65
  
  Pages: 540-550
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction.2003
- Author(s)
  Ogawa D, Shikata K, Honke K, Sato S, Matsuda M, Nagase R, Tone A, Okada S, Usui H, Wada J, Miyasaka M, Kawashima H, Suzuki Y, Suzuki T, Taniguchi N, Hirahara Y, Tadano-Aritomi K, Ishizuka I, Tedder TF, Makino H.
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 2085-2090
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction.2003
- Author(s)
  Ogawa D, Shikata K, Honke K, Sato S, Matsuda M, Nagase R, Tone A, Okada S, Usui H, Wada J, Miyasaka M, Kawashima H; Suzuki Y, Suzuki T, Taniguchi N, Hirahara Y, Tadano-Aritomi K, Ishizuka I, Tedder TF, Makino H.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 2085-2090
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590850
[Journal Article] Elevated serum MCP-4 levels in overweight subjects and its correlation with chronic inflammation.
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obes Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of Tim44 by reducing mitochondrial superoxide production.
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makono H
- Journal Title
  
  J Am Soc Nephrol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370319
[Journal Article] Effects of uncertainty and coping on dietary behaviors in patients with diabetic nephropathy : Development of a model to predict dietary behavior
- Author(s)
  Kazuko, sumiyoshi, Chieko, Kawata, Kenichi, Shikata, Hirofumi, makino
- Journal Title
  
  Diabetes educator, during contribution
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Journal Article] Elevated serum MCP-4 levels in overweight subjects and its correlation with chronic inflammation.
- Author(s)
  Hashimoto I, Wada J, Hida A, Baba M, Miyatake N, Eguchi J, Shikata K, Makino H
- Journal Title
  
  Obes Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Journal Article] Phenotypic change of macrophages in the progression of diabetic nephropathy ; sialoadhesin-positive activated macrophages are increased in diabetic kidney
- Author(s)
  Nagase R, Kajitani N, Shikata K, Ogawa D, Kodera R, Okada S, Kido Y, Makino H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: (In press)
- NAID
  10031122261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591031
[Journal Article] Therapeutic approach for diabetic nephropathy using gene delivery of Tim44 by reducing mitochondrial superoxide production.
- Author(s)
  Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H
- Journal Title
  
  J Am Soc Nephrol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571025
[Presentation] わが国の臨床研究から何を学べば良いか：DNETT-Japan2016
- Author(s)
  四方賢一
- Organizer
  第50回糖尿病学の進歩　シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2016-02-10
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 腎症の成因と新たな治療標的2015
- Author(s)
  四方賢一
- Organizer
  第30回日本糖尿病合併症学会、第21回日本糖尿病眼学会
- Place of Presentation
  名古屋市
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 糖尿病腎症の診断と治療2015
- Author(s)
  四方賢一
- Organizer
  日本内科学会北陸支部第66回生涯教育講演会
- Place of Presentation
  金沢市
- Year and Date
  2015-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 腎症治療薬開発の現状と課題、2015
- Author(s)
  四方賢一
- Organizer
  第58回日本糖尿病学会年次学術集会　シンポジウム
- Place of Presentation
  下関市
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 糖尿病性腎症診療の現状と課題2015
- Author(s)
  四方賢一
- Organizer
  第45回日本腎臓学会西部学術集会ワークショップ
- Place of Presentation
  金沢市
- Year and Date
  2015-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 腎症に対する薬物療法2014
- Author(s)
  四方賢一
- Organizer
  第29回日本糖尿病合併症学会シンポジウム3
- Place of Presentation
  東京都
- Year and Date
  2014-10-03
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] 糖尿病性腎症と炎症～新規治療薬開発への道～2014
- Author(s)
  四方賢一
- Organizer
  第57回日本腎臓学会学術総会　教育セッション2　糖尿病腎症
- Place of Presentation
  横浜市
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] Activation of Peroxisome Proliferator-activated ReceptorδInhibits Streptozotocin-induced Diabetic Nephropathy Through Anti-inflammatory Mechanisms in Mice2011
- Author(s)
  Tachibana H, Ogawa D, Matsushita Y, Yamamoto N, Toyota N, Sato C, Wada J, Shikata K, Makino H
- Organizer
  American Diabetes Association 71st Scientific Sessions
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] 糖尿病性腎症の治療における新しい展開～MIcroinflammationを標的とした治療戦略～2011
- Author(s)
  四方賢一
- Organizer
  第75回日本循環器学会
- Place of Presentation
  横浜市
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] 糖尿病性腎症の治療における新しい展開～Microinflammmationを標的とした治療戦略～2011
- Author(s)
  四方賢一
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Activation of Peroxisome Proliferator-activated ReceptorδInhibits Streptozotocin-induced Diabetic Nephropathy Through Anti-inflammatory Mechanisms in Mice2011
- Author(s)
  Ogawa D, Wada J, Matsushita Y, NakatsukaA, Murakami K, Kanzaki M, Shikata K, Makino H
- Organizer
  Keystone Symposia
- Place of Presentation
  Keystone, Colorado, USA
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] 糖尿病性腎症治療の最前線2011
- Author(s)
  四方賢一
- Organizer
  第26回糖尿病合併症学会
- Place of Presentation
  大宮市
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Telmisartan attenuates diabetic nephropathy through anti-oxidative and anti-inflammatory actions via activation of peroxisome proliferator-activated recep tor-γ2011
- Author(s)
  Kajitani N, Shikata K, Kodera R, Miyamoto S, Hirota D, Sato C, Wada J, Ogawa D, and Makino H
- Organizer
  47th AnnualMeeting of the European Ass ociation for the Study of Diabetes Lisbon Portugal
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] 糖尿病性腎症の成因としてのMicroinflammation2010
- Author(s)
  四方賢一
- Organizer
  第53回日本糖尿病学会
- Place of Presentation
  ホテルグランヴィア岡山
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] PPARδ-mediated anti-inflammat orymechanisms inhibit streptozotocin-i nduceddiabetic nephropathy2010
- Author(s)
  Ogawa D, Matsushita Y, Shikata K, Wada J, Sato C, Makino H
- Organizer
  ISN-NEXUS K yoto in 2010
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Exendin-4a meliorates renal injuries through an ti-oxidative and anti-inflammatory ef fectsin type 1 diabetic rats2010
- Author(s)
  Kodera. R, Kataoka H, Shikata K, Sato C, Sasa ki M, Nishishita S, Miyamoto S, Hirota D, Kajitani N, Ogawa O, Makino H
- Organizer
  46th EASD Annualmeeting Stocholm
- Place of Presentation
  Sweden
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] PPARδ-mediated anti-inflammatory mechanisms inhibit streptozotoci n-induced diabetic nephropathy2010
- Author(s)
  Ogawa D, Matsushita Y, Shikata K, Wada J, Sato C, Makino H
- Organizer
  Keyston e Symposia
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] PPARδ-mediated anti-inflammatory mechanisms inhibit streptozotocin-induced diabeticnephropathy2010
- Author(s)
  Ogawa D, Matsushita Y, Shikata K, Wada J, Sato C, Makino H
- Organizer
  The 2nd Scientific Meeting of the Asian Association for the Study of Diabetes
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] 糖尿病とCKD～管理の面から～チーム医療による集約的治療の意義2009
- Author(s)
  四方賢一
- Organizer
  第52回日本糖尿病学会年次学術集会ジョイントシンポジウム4
- Place of Presentation
  大阪
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Exendin-4 ameliorates renalinjuries through anti-inflammatory effects in type 1 diab etic rats2009
- Author(s)
  Kodera R, Kataoka H, Shikata K, Makino H
- Organizer
  Asia Islet Biology and Incretin Symposium(AIBIS)
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Exendin-4 ameliorates renalinjuries through anti-oxidative a nd anti-inflammatory effects in type 1 d iabetic rats2009
- Author(s)
  Kodera R, Kataoka H, Shikata K, Sato C, Sasaki M, Nishishita S, Miyamoto S, Hirota D, Kajitani N, Ogawa D, Makino H
- Organizer
  45th EASD Annual meeting
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Cholecystokinin amelioratesdia betic renal injuries via anti-inflam matory effects2009
- Author(s)
  Miyamoto S Shikata K Sasaki M Nishishita S Sato C Kataoka H Kodera R Hirota D Kajitani N Makino H
- Organizer
  45th EASD Annual Meeting
- Data Source
  KAKENHI-PROJECT-21591031
[Presentation] Microinflammation is a common pathway in the pathogenesis of diabetic nephropathy and cardiovascucomplications2008
- Author(s)
  Kenichi SHIkata
- Organizer
  The 8^<th> Japan-China Diabetes Symposium
- Place of Presentation
  和歌山市
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] 糖尿病性腎症の成因とMicroinflammation-新しい治療戦略の開発を目指して-2008
- Author(s)
  四方賢一
- Organizer
  第51回日本糖尿病学会学術総会シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] Protective roles of Cholecystokinin against progression of diabetic nephropathy2008
- Author(s)
  Satoshi Miyamoto, Kenichi Shikata, Motofumi Sasaki, Shingo Nishishita, Chikage Sato, Hitomi Kataoka, Ryo Kodera, Daisho Hirota, Nobuo Kajitani, Jun Wada, Hirofumi Makino
- Organizer
  44th EASD Annual Meeting
- Place of Presentation
  Roma, Italy
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] Cholecystokinin plays protective against progression of diabetic nephropathy2008
- Author(s)
  Miyamoto S, Shikata K, Sasaki M, Nishishita S, Sato C, Kataoka H, KodeR, Hirota D, Kajitani N, Makino H.
- Organizer
  ISN Nexus Symposium on Diabetes and the Kidney
- Place of Presentation
  Dublin, Ireland
- Year and Date
  2008-06-09
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] Cholecystokplays protective roles against progression of diabetic nephropathy2008
- Author(s)
  Miyamoto S, Shikata K, Sasaki M, Nishishita S, Sato C, Kataoka H, Kodera R, Hirota D, Makino H
- Organizer
  The Shiga International Symposium on Diabetic Nephropathy
- Place of Presentation
  滋賀県大津市
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] 糖尿病性腎症の成因とMicroinflammation-新しい治療戦略の開発を目指して-2008
- Author(s)
  四方賢一
- Organizer
  第5 1回日本糖尿病学会学術総会シンポジウム3
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] A trial of nursing model construction of the diabetic nephropathy2007
- Author(s)
  Kazuko, Sumiyoshi, Chieko, Kawata, Kenichi, Shikata, Hirofumi, Makino, Miyuki, Nakao, Mutuko, Ohashi, Sachiko, Takatori
- Organizer
  12th Annual Meeting of the Japan Academy of Diabetes Education and Nursing
- Place of Presentation
  Chiba
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] 糖尿病動物と合併症研究:成因解明から治療法探索まで2007
- Author(s)
  四方賢一
- Organizer
  第21回日本糖尿病・肥満動物学会シンポジウム
- Place of Presentation
  盛岡
- Year and Date
  2007-02-10
- Data Source
  KAKENHI-PROJECT-19590952
[Presentation] 糖尿病腎症患者の看護モデル作成の試み2007
- Author(s)
  住吉和子, 川田智恵子, 四方賢一, 槇野博史, 中尾美幸, 大橋睦子, 高取佐智子
- Organizer
  第12回日本糖尿病教育・看護学会学術集会
- Place of Presentation
  千葉
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] 糖尿病性腎症の患者の認識に影響を与える要因2006
- Author(s)
  住吉和子, 川田智恵子, 四方賢一, 槇野博史, 中尾美幸, 大橋睦子, 高取佐智子, 中内麻里
- Organizer
  第11回日本糖尿病教育・看護学会学術集会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] Factors affecting the awareness of patients with diabetic nephropathy2006
- Author(s)
  Kazuko, Sumiyoshi, Chieko, Kawata, Kenichi, Shikata, Hirofumi, Makino, Miyuki, Nakao, Mutuko, Ohashi, Sachiko, Takatori, Mari, Nakauchi
- Organizer
  11th Annual Meeting of the Japan Academy of Diabetes Education and Nursing
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] Factors affecting the dietary management of patients with diabetic nephropathy2005
- Author(s)
  Kazuko, Sumiyoshi, Chieko, Kawata, Kenichi, Shikata, Hirofumi, Makino
- Organizer
  10th Annual Meeting of the Japan Academy of Diabetes Education and Nursing
- Place of Presentation
  Fukuoka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] 糖尿病腎症の看護〜意識付けへのアプローチ〜2005
- Author(s)
  佐々木可菜, 奥道保子, 宮村純子, 笹田雅子, 下宮暁子, 四方賢一, 槇野博史, 住吉和子
- Organizer
  第10回日本糖尿病教育・看護学会学術集会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] 糖尿病腎症患者の食事管理行動に影響を与える要因2005
- Author(s)
  住吉和子, 川田智恵子, 四方賢一, 槇野博史
- Organizer
  第10回日本糖尿病教育・看護学会学術集会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] Nursing care of diabetic nephropathy : increasing awareness2005
- Author(s)
  Kana, Sasaki, Yasuko, Okumichi, junko, Miyamura, Masako, Sasada, Akiko, Shimomiya, Kenichi, Shikata, Hirofumi, Makino, Kazuko, Sumiyoshi
- Organizer
  10th Annual Meeting of the Japan, Academy of Diabetes Education and Nursing
- Place of Presentation
  Fukuoka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592245
[Presentation] 糖尿病性腎症の診断と治療
- Author(s)
  四方賢一
- Organizer
  第48回糖尿病学の進歩
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] インクレチン関連薬の長期展望
- Author(s)
  四方賢一
- Organizer
  第56回日本糖尿病年次学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-25461224
[Presentation] Challenges of regional support systems for education of patients with diabetic nephropathy(kidney disease) in Okayama
- Author(s)
  Kazuko Sumiyoshi,Chieko Kawata, Woesook Kim, Yoshimi Matuda, Kenichi Shikata, Masahiro Yamashita
- Organizer
  The 1stAsia Future Conference
- Place of Presentation
  Bangkok in Thailand
- Data Source
  KAKENHI-PROJECT-22592606

1. MAKINO Hirofumi (50165685)

# of Collaborated Projects: 17 results

# of Collaborated Products: 119 results
2. WADA Jun (30294408)

# of Collaborated Projects: 10 results

# of Collaborated Products: 111 results
3. KAWATA Chieko (60010013)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
4. SUMIYOSHI Kazuko (20314693)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. KASHIHARA Naoki (10233701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 宮本聡 (60779429)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. OTA Zensuke (90032870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KIM Woesook (90331371)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. IKEDA Shyuji (10212771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAMAMURA Masahiro (80252956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ICHIMURA Mituko (40203111)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. YAMAJI Hiroaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TSUCHIYAMA Yoshinori

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. HIDA Kazuyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 林佳子

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. YAMASHITA Masahiro (30230428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. TOMIOKA Kayoko (90368671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Kodera Ryo (70610921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. OGURA Toshio (80214097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NIMOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HORIUCHI Masakimi (10117377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MURAYAMA Yoji (50029972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. FUKUDA Tetsuya (00304345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. NAKAMURA Yoshio (30314686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NAKAO Miyuki (00316126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
27. NAKANISHI Yoshiko (50217783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 松浦栄次 (20181688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 稲垣純子 (90271056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 太湯好子 (10190117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 杉本光 (70284099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 松田充浩 (20314669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 櫻井淳 (30444657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 堀田勝幸 (70379816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 大野彩 (20584626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 加藤有加 (50544904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MATHUDA Yoshimi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. SEKI Akiho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. SADA Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KUNITOMI Mie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 小川さえ子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 久代昌彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIKATA Kenichi 四方 賢一

四方 賢一 シカタ ケンイチ

Research Projects

Research Products

Co-Researchers

Development of the new therapeutic strategy for diabetic nephropathy by modulation of inflammasome.Principal InvestigatorOngoing

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Quality management of Advanced medical care clinical resarch under Clinical Trial Act for pharmaceutial approval applicationOngoing

Principal Investigator

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3次元マルチオミックス解析による糖尿病性腎症の新規治療標的の探索と同定Ongoing

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

糖尿病性腎症に対する新規治療薬の開発～インフラマソームを標的とした探索的研究～Principal InvestigatorOngoing

Principal Investigator

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Principal Investigator

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Investigation of the novel therapeutic targets for diabetic nephropathy.Principal Investigator

Principal Investigator

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Principal Investigator

Project Period (FY)

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Development of the novel therapeutic strategy for diabetic nephropathy through anti-inflammatory effects.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Exploratory research to development of novel therapeutic strategy for diabetic nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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Novel therapeutic targets for diabetic nephropathy.Principal Investigator

Principal Investigator

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Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Principal Investigator

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SHIKATA Kenichi 四方賢一

四方賢一シカタケンイチ