HOTTA Katsuyuki 堀田勝幸

… Alternative Names

堀田勝幸ホツタカツユキ

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Researcher Number	70379816
Other IDs
Affiliation (Current)	2022: 岡山大学, 大学病院, 教授
Affiliation (based on the past Project Information) *help	2015 – 2021: 岡山大学, 大学病院, 教授 2014: 岡山大学, 大学病院, 講師 2013 – 2014: 岡山大学, 大学病院, 助教 2008: 岡山大, 助教 2007: Okayama University, 保健環境センター, 助教 2006: 岡山大学, 保健環境センター, 助手
Review Section/Research Field	Principal Investigator Public health/Health science / Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Respiratory organ internal medicine / Basic Section 90130:Medical systems-related / Basic Section 90140:Medical technology assessment-related
Keywords	Principal Investigator 肺癌 / クォンティフェロン / 結核検診 / ツベルクリン反応検査 / 医療系大学生 / 結核健診 / クォンティフェロン検査 / EGFR / IL-6 / チロシンキナーゼ阻害薬 … More / EGFR遺伝子変異陽性非小細胞肺がん / EGFR-TKI / インターロイキン6（IL-6） / EGFR変異陽性肺癌 / EGFR肺癌 … More Except Principal Investigator EGFR遺伝子改変マウス / afatinib / everolimus (mTOR阻害薬), / JAK-1/2 inhibitors / cetuximab / bevacizumab / Ogg1ホモノックアウトマウス / NNK / EGFR / everolims / AZD1480 / gefitinib / 用量依存性 / 遺伝子改変マウス / ｍTOR阻害薬 / everolimus / JAK1/2阻害薬 / BIBW2552 / mTOR阻害薬 / 検査・診断システム / 腫瘍検査学 / 生体情報・計測 / 先制医療 / エピゲノム / メチル化 / 固形癌 / 臨床検査システム / 遺伝子検査学 / 予防医学 / 悪性腫瘍 / 臨床研究法 / 特定臨床研究 / 先進医療 / 品質マネジメント / 薬事承認申請 / データマネジメント Less

EGFR肺癌における第3世代EGFR-TKI耐性へのIL-6の関与と克服の検討Principal Investigator
- Principal Investigator
  
  堀田勝幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
Quality management of Advanced medical care clinical resarch under Clinical Trial Act for pharmaceutial approval application
- Principal Investigator
  
  櫻井淳
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Okayama University
Preemptive Medicine to Solid Tumors based on Epigenomics
- Principal Investigator
  
  NAGASAKA TAKESHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kawasaki Medical School
Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutationsPrincipal Investigator
- Principal Investigator
  
  Hotta Katsuyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Okayama University
Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mouse
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
医療系大学生に対するクォンティフェロン検査を用いた結核対策の精度向上に関する検討Principal Investigator
- Principal Investigator
  
  堀田勝幸
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Okayama University

All 2018 2015 2014 2013 2012 2011 2007

All Journal Article Presentation

[Journal Article] Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations2018
- Author(s)
  Tamura T, Kato Y, Ohashi K, Ninomiya K, Makimoto G, Gotoda H, Kubo T, Ichihara E, Tanaka T, Ichimura K, Maeda Y, Hotta K, Kiura K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 495 Pages: 360-367
- DOI
  10.1016/j.bbrc.2017.10.175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-26430163, KAKENHI-PROJECT-16K15458
[Journal Article] Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model.2014
- Author(s)
  Ochi N, Takigawa N, Harada D, Yasugi M, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Experimental Cell Research
  
  Volume: 322 Pages: 168-177
- DOI
  10.1016/j.yexcr.2014.01.007
- NAID
  120005517858
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene.2014
- Author(s)
  Isozaki H, Yasugi M, Takigawa N, Hotta K, Ichihara E, Taniguchi A, Toyooka S, Hashida S, Sendo T, Tanimoto M, Kiura K.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 2014 Pages: 963-968
- DOI
  10.1093/jjco/hyu110
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.2014
- Author(s)
  Yasugi M, Takigawa N, Ochi N, Ohashi K, Harada D, Ninomiya T, Murakami T, Honda Y, Ichihara E, Tanimoto M, Kiura K.
- Journal Title
  
  Exp Cell Reｓ
  
  Volume: 326 Pages: 201-209
- DOI
  10.1016/j.yexcr.2014.04.012
- NAID
  120005526613
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells.2013
- Author(s)
  Takeda H, Takigawa N, Ohashi K, Minami D, Kataoka I, Ichihara E, Ochi N, Tanimoto M, Kiura K.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 319 Pages: 140-148
- DOI
  10.1158/1541-7786.mcr-12-0401
- NAID
  120005359097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
[Journal Article] Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations.2013
- Author(s)
  Ichihara E, Hotta K, Takigawa N, Kudo K, Kato Y, Honda Y, Hayakawa H, Minami D, Sato A, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Lung Cancer.
  
  Volume: 81 Pages: 435-439
- DOI
  10.1016/j.lungcan.2013.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Establishment of pemetrexed-resistant non-small cell lung cancer cell lines2011
- Author(s)
  Zhang D, Ochi N, Takigawa N, Tanimoto I, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Lett
  
  Volume: 309 Pages: 228-235
- DOI
  10.1016/j.canlet.2011.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Whole Blood Interferon-gamma Assay for Baseline Tuberculosis Screening among Japanese Healthcare Students2007
- Author(s)
  Hotta K, et. al.
- Journal Title
  
  Plos One 2(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790397
[Presentation] Interleukin-6 Is a Valuable Predictive Marker for Therapeutic Effect of Gefitinib in Patients with Advanced NSCLC Harboring EGFR Mutations2015
- Author(s)
  Y. Kato, K. Hotta, T. Tamura, T. Tanaka, K. Ichimura, K. Ohashi, T. Kubo, E. Ichihara, M. Tanimoto, K. Kiura
- Organizer
  第16回世界肺癌会議
- Place of Presentation
  米国コロラド州デンバー
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430163
[Presentation] ALK inactivation induced acquired resistance to alectinib in lung cancer harboring EML4-ALK fusion gene.2014
- Author(s)
  Hideko Isozaki, Eiki Ichihara, Masayuki Yasugi, Ocihi Nobuaki, Katsuyuki Hotta, Nagio Takigawa, Toshiaki Sendo, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  The 105th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA. USA
- Year and Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Afatinib prolonged survival in EGFR-driven lung cancer model compared to gefitinib2012
- Author(s)
  Takashi Ninomiya, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura, Nagio Takigawa, Nobuaki Ochi, Masayuki Yasugi, Daijiro Harada.
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Effect of AZD1480 on lung tumor in transgenic mice carrying activating EGFR mutation2012
- Author(s)
  Toshi Murakami, Nagio Takigawa, Takashi Ninomiya, Nobuhiro Honda, Hideko Isozaki, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Role of ERK reactivation mediated by Src in acquired resistance to gefitinib in non-small cell lung cancer with EGFR mutation2011
- Author(s)
  Ochi N, Takigawa N, Ohashi K, Takeda H, Fujii M, Kubo T, Ichihara E, Hotta K, Tanimoto M, Kiura K
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] 医療系大学生に対するクォンティフェロン検査(QFT)を用いた結核対策の精度向2007
- Author(s)
  堀田勝幸、他
- Organizer
  第42回日本呼吸器学会中国四国地方会
- Place of Presentation
  広島
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-18790397
[Presentation] 医療系大学生に対するクォンティフェロン検査(QFT)を用いた結核対策の精度向2007
- Author(s)
  堀田勝幸、他
- Organizer
  第45回全国大学保健管理研究集会
- Place of Presentation
  別府
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18790397

1. KIURA Katsuyuki (10243502)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. 加藤有加 (50544904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. TKIGAWA Nagio (60325107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. TAKATA Minoru (30281728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. NAKABEPPU Yusaku (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOSHINO Tadashi (70183704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAGASAKA TAKESHI (30452569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 市原英基 (40549705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. 山口佳之 (10230377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 楳田祐三 (10573735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 堅田洋佑 (20716881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 西田直生志 (60281755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 母里淑子 (70708081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 櫻井淳 (30444657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 四方賢一 (00243452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 大野彩 (20584626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Tamura Tomoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. Ninomiya Kiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. Ohashi Kadoaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. Makimoto Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 越智宣昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 久保寿夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HOTTA Katsuyuki 堀田 勝幸

堀田 勝幸 ホツタ カツユキ

Research Projects

Research Products

Co-Researchers

EGFR肺癌における第3世代EGFR-TKI耐性へのIL-6の関与と克服の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Quality management of Advanced medical care clinical resarch under Clinical Trial Act for pharmaceutial approval application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preemptive Medicine to Solid Tumors based on Epigenomics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

医療系大学生に対するクォンティフェロン検査を用いた結核対策の精度向上に関する検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells.2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of pemetrexed-resistant non-small cell lung cancer cell lines2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole Blood Interferon-gamma Assay for Baseline Tuberculosis Screening among Japanese Healthcare Students2007

HOTTA Katsuyuki 堀田勝幸

堀田勝幸ホツタカツユキ