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KANAI Yae  金井 弥栄

ORCIDConnect your ORCID iD *help
Researcher Number 00260315
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 慶應義塾大学, 医学部(信濃町), 教授
2016 – 2017: 慶應義塾大学, 医学部, 教授
2011 – 2014: 独立行政法人国立がん研究センター, 研究所, 分野長
2012: 国立がん研究センター, 研究所, 副所長
2012: 独立行政法人国立がん研究センター, その他部局等, その他 … More
2011: 国立がん研究センター研究所, 病理部, 部長
2010: 国立がん研究センター, 病理部, 部長
2005 – 2006: 国立がんセンター(研究所及び東病院臨床開発センター), 病理部, 部長
2004: 国立がんセンター(研究所), 病理部, 部長
2004: 国立がんセンター(研究所), 研究所病理部, 部長
2003: 国立がんセンター, 研究所・病理部, 部長
1999 – 2001: 国立がんセンター, 研究所・病理部, 室長
1999: National Cancer Center Research Institute East, Pathology Division, Head., 支所・臨床腫瘍病理部, 室長
1998: 国立がんセンター, 研究所病理部, 室長
1998: National Cancer Center Reaearch Institute East, Section Head, 病理部, 室長
1997: 国立がんセンター, 研究所・病理部, 研究員
1997: 国立がんセンター, 研究所病理部, 研究員
1995 – 1996: 国立がんセンター研究所, 病理部, 研究員
1994: 国立がんセンター, 研究所病理部, 研究員 Less
Review Section/Research Field
Principal Investigator
Human pathology / Biological Sciences / Basic Section 49020:Human pathology-related / Tumor diagnostics / Human pathology / Experimental pathology
Except Principal Investigator
Basic Section 56030:Urology-related / Human pathology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied health science / Tumor diagnostics / Biomedical engineering/Biological material science
Keywords
Principal Investigator
DNAメチル化 / 多段階発がん / DNMT1 / 前がん状態 / DNAメチルトランスフェラーゼ / CpGアイランドメチル化形質 / DNA methylation / DNMT3b / 慢性肝炎 / 移行上皮がん … More / 膀胱がん / ヘテロ接合性喪失 / 肝細胞がん / E-カドヘリン / がん浸潤 / Multi-omics analysis / Epigenome / NASH / Hepatocellular carcinoma / 病理画像 / オミックス解析 / 人工知能 / 病理診断 / リスク診断 / エピゲノムワイド関連解析 / 膵がん / エピゲノムワイド関連解析 (EWAS) / エピゲノム / Multistage carcinogenesis / Precancerous condition / Chromosomal instability / CpG island methylator phenotype / DNA methyltransferase / hMLH1 / EBウイルス / 前がん段階 / 傍セントロメアサテライト領域 / 腎細胞がん / 浸潤性膵管がん / Pan IN / 膵管がん / PanIN / 慢性膵炎 / CpGアイランド / 染色体不安定性 / 肺がん / 慢性閉塞性肺疾患 / ヒストンアセチルトランスフェラーゼ / ヒストンメチルトランスフェラーゼ / ヒストンアセチル化酵素 / ヒストンメチル化酵素 / 肝がん / 腎がん / ヒストン修飾 / 発がんリスク評価 / BAMCA法 / 肝硬変症 / 肝炎ウイルス / 扁平上皮がん / 異形成 / 子宮頚がん / MeCP2 / メチルCpG結合蛋白 / 腸上皮化生 / 慢性胃炎 / 前がん状態、胃がん / HIC-1 / B4-2 / TROP2 / Wip1 / がん抑制遺伝子 / 発現制御 / 5-azacytidine / scattering / 上皮内進展 / ラミニン / インテグリン / 上皮内がん / 第16染色体 / 発現調節 / 細胞間接着 / 細胞接着 / c-erbB-2 / β-catenin / α-catenin / E-cadherin … More
Except Principal Investigator
エピゲノム / オルガノイド培養 / 新規治療開発 / 老化 / 幹細胞 / シグナル伝達 / c-erbB-2 / チロシンリン酸化 / マイクロRNA / エピゲノム解析 / 切除不能尿路上皮がん / 抗加齢 / オルガノイド / NAD+ / 尿路上皮癌 / ヒストン修飾 / 化学療法抵抗性 / エピジェネティクス治療 / 転移性膀胱癌 / 化学療法耐性 / 膀胱がん / 2次治療 / 5-Aza-CdR / エピジェネティクス / 膀胱癌 / 腸管上皮 / ステムセルエイジング / 腸管上皮幹細胞 / エピゲノム変化 / 加齢 / 癌 / 胆道・膵臓がん / 個別化治療 / がん幹細胞 / 膵臓がん / 胆道がん / Tyrosine phosphorylation / Invasion / Cell adhesion system / Signal transduction / Growth factor receptor / β-catenin / 細胞接着因子 / がん浸潤 / 細胞接着分子 / 増殖因子受容体 / βカテニン / signal transduction / tyrosine phosphorylation / integrin / catenin / cadherin / invasion and metastasis / cell adhesion / DNAメチル化 / カドヘリン・カテニン / 多段階発がん / がん間質相互作用 / インテグリン / カテニン / カドヘリン / 浸潤・転移 / 細胞接着 / 担癌動物 / 癌遺伝子 / 食道腺癌 / 癌幹細胞 / NOGマウス / 5-FU / シスプラチン / 胃癌 / 細胞内導入 / 担がん動物 / 胃がん / がん遺伝子 / アパタイトナノキャリア Less
  • Research Projects

    (21 results)
  • Research Products

    (190 results)
  • Co-Researchers

    (37 People)
  •  Multi-omics analysis - particularly epigenomic analysis - to elucidate the nature of NASH-derived hepatocellular carcinoma and identify therapeutic targetsPrincipal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Keio University
  •  尿路上皮がんに対する新規エピゲノム解析による治療効果予測バイオマーカー開発

    • Principal Investigator
      西山 直隆
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      University of Toyama
  •  Pathological diagnosis based on integration of morphological images and multi-layer omics data by artificial intelligencePrincipal Investigator

    • Principal Investigator
      Kanai Yae
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Keio University
  •  Established epigenetic treatment for chemotherapy-resistant metastatic bladder cancer

    • Principal Investigator
      Nishiyama Naotaka
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      University of Toyama
  •  Elucidation of Aging Mechanisms by Regulation of NAD+ and Epigenome and Development of New Anti-Aging Interventions

    • Principal Investigator
      Saito Yoshimasa
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Keio University
  •  Risk estimation of pancreatic adenocarcinomas based on epigenome-wide association studyPrincipal Investigator

    • Principal Investigator
      Kanai Yae
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Keio University
  •  Investigation of the molecular mechanism underlying aging based on epigenome alterations in intestinal epithelial stem cells

    • Principal Investigator
      SAITO Yoshimasa
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Keio University
  •  Diagnostic and therapeutic strategies targeting microRNAs and epigenome alterations in biliary tract and pancreatic cancer stem cells

    • Principal Investigator
      Saito Yoshimasa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Keio University
  •  Molecular mechanisms of DNA methylation alterations in precancerous conditionsPrincipal Investigator

    • Principal Investigator
      KANAI Yae
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      National Cancer Center Japan
  •  The microRNAsfor the diagnosis and treatment of uppergastro-intestinal malignancy - application of appatite-nanocarrier -

    • Principal Investigator
      SUZUKI Hidekazu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Keio University
  •  漫性肝炎を背景とする肝多段階発がん過程におけるDNAメチル化の変化Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  DNAメチル化異常に基づく発がんリスクの評価とがんの早期診断に関する研究Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Alterations of DNA methyltransferases during multistage human carcinogenesisPrincipal Investigator

    • Principal Investigator
      KANAI Yae
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  ヒト多段階発がんにおけるDNAメチルトランスフェラーゼならびにメチルCpG結合蛋白の異常Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  DNAメチル化によって発現制御され胃がんの発生・進展に寄与する遺伝子の単離Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  膀胱移行上皮がん上皮内進展の分子機構の解明Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  ELUDICATION OF ASSOCIATION AND SIGNAL TRANSDUCTION PATHWAY BETWEEN BETA-KATENIN AND GROWTH FACTOR RECEPTOR AT THE CANCER INVASION

    • Principal Investigator
      OCHIAI Atsushi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  肝発がんならびに肝がんの生物学的特性の決定におけるDNAメチル化の意義Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  がん細胞におけるE-カドヘリン発現調節機構の解析Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Intercellular interaction and signal transduction in cancer morphogenesis

    • Principal Investigator
      HIROHASHI Setsuo
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute
  •  がんの浸潤・転移における細胞接着分子異常の関与Principal Investigator

    • Principal Investigator
      金井 弥栄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] ピジェネティクス―基礎研究から産業応用への展望―2014

    • Author(s)
      金井弥栄, 新井恵吏.
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Book] DNA methylation alterations in human cancers. In: Epigenetics in Human Disease.2012

    • Author(s)
      Kanai Y et al.
    • Total Pages
      24
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Book] DNA methylation alterations in human cancers. In : Epigenetics in Human Disease2012

    • Author(s)
      Kanai Y, et al
    • Total Pages
      24
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Book] Role of immunohistochemical expression of DNA methyltransferase 1 protein in gastric carcinoma. In : Handbook of Immunohistochemistry and in sity Hybridization of Human Carcinomas. Vol.4 : Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma.2006

    • Author(s)
      Yae Kanai, et al.(ed.by Hayat, M.A.)
    • Publisher
      Elsevier (in press)
    • Data Source
      KAKENHI-PROJECT-17013093
  • [Book] Role of immunohistochemical expression of DNA methyltransferase 1 protein in gastric carcinoma. In: Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas. Vol.4: Molecular Genetics, GastrointestinalCarcinoma, and Ovarian Carcinoma, ed. Hayat, M.A.2006

    • Author(s)
      Yae Kanai, et. al.
    • Publisher
      Elsevier,CA,
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Book] Role of immunohistochemical expression of DNA methyltransferase 1 protein in gastric carcinoma. Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas. Vol. 4:Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma.2006

    • Author(s)
      Yae Kanai, et al.(ed.by Hayat, M.A.)
    • Publisher
      Elsevier(in press)
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Book] Role of immunohistochemical expression of DNA methyltransferase 1 protein in gastric carcinoma. In : Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas. Vol.4 : Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma,(ed.Hayat,M.A)2006

    • Author(s)
      Yae Kanai, et al.
    • Publisher
      Elsevier,CA
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Molecular pathological approach to cancer epigenomics and its clinical application2024

    • Author(s)
      Kanai Yae
    • Journal Title

      Pathology International

      Volume: 74 Issue: 4 Pages: 167-186

    • DOI

      10.1111/pin.13418

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Journal Article] Epigenetic profile of Japanese supercentenarians: a cross-sectional study.2023

    • Author(s)
      Komaki S, Nagata M, Arai E et al (19人中3番目)
    • Journal Title

      Lancet Healthy Longev

      Volume: 4 Issue: 2 Pages: e83-e90

    • DOI

      10.1016/s2666-7568(23)00002-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06947, KAKENHI-PROJECT-21H02705
  • [Journal Article] DNA methylation alterations of ADCY5, MICAL2, and PLEKHG2 during the developmental stage of cryptogenic hepatocellular carcinoma2023

    • Author(s)
      Makiuchi Satomi、Tian Ying、Fujimoto Mao、Kuramoto Junko、Tsuda Noboru、Ojima Hidenori、Gotoh Masahiro、Hiraoka Nobuyoshi、Yoshida Teruhiko、Kanai Yae、Arai Eri
    • Journal Title

      Hepatology Research

      Volume: 54 Issue: 3 Pages: 284-299

    • DOI

      10.1111/hepr.13984

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06947, KAKENHI-PROJECT-21H02705
  • [Journal Article] The oligodendroglial histological features are not independently predictive of patient prognosis in lower-grade gliomas2022

    • Author(s)
      Pareira Eriel Sandika、Shibuya Makoto、Ohara Kentaro、Nakagawa Yu、Kanazawa Tokunori、Kamamoto Dai、Kato Yasutaka、Arai Eri、Aimono Eriko、Yoshida Kazunari、Nishihara Hiroshi、Kanai Yae、Sasaki Hikaru
    • Journal Title

      Brain Tumor Pathology

      Volume: - Issue: 2 Pages: 79-87

    • DOI

      10.1007/s10014-022-00426-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09464, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-21K09161, KAKENHI-PROJECT-22K06947
  • [Journal Article] Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles.2022

    • Author(s)
      Hirano T, Arai E, Fujimoto M et al (11人中2番目)
    • Journal Title

      J Gynecol Oncol

      Volume: 33 Issue: 6

    • DOI

      10.3802/jgo.2022.33.e74

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06947, KAKENHI-PROJECT-21H02705
  • [Journal Article] Quantification of DNA methylation for carcinogenic risk estimation in patients with non-alcoholic steatohepatitis.2022

    • Author(s)
      Kuramoto J, Arai E, Fujimoto M et al (19人中2番目)
    • Journal Title

      Clin Epigenetics

      Volume: 14 Issue: 1 Pages: 168-168

    • DOI

      10.1186/s13148-022-01379-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06947, KAKENHI-PROJECT-22K11760, KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-19K11758, KAKENHI-PROJECT-20K11663
  • [Journal Article] DNA methylation status of the SPHK1 and LTB genes underlies the clinicopathological diversity of non-alcoholic steatohepatitis-related hepatocellular carcinomas.2022

    • Author(s)
      Tsuda N, Tian Y, Arai E et al (11人中11番目)
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: - Issue: 8 Pages: 1-16

    • DOI

      10.1007/s00432-022-04445-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06947, KAKENHI-PROJECT-21H02705
  • [Journal Article] CD163‐positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma2021

    • Author(s)
      Matsubara Eri、Komohara Yoshihiro、Shinchi Yusuke、Mito Remi、Fujiwara Yukio、Ikeda Koei、Shima Toshiyuki、Shimoda Masayuki、Kanai Yae、Sakagami Takuro、Suzuki Makoto
    • Journal Title

      Pathology International

      Volume: 71 Issue: 10 Pages: 666-673

    • DOI

      10.1111/pin.13144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-21H02705
  • [Journal Article] Molecular classification of gastric cancer predicts survival in patients undergoing radical gastrectomy based on project HOPE2021

    • Author(s)
      Furukawa Kenichiro、Hatakeyama Keiichi、Terashima Masanori、Nagashima Takeshi、Urakami Kenichi、Ohshima Keiichi、Notsu Akifumi、Sugino Takashi、Yagi Taisuke、Fujiya Keiichi、Kamiya Satoshi、Hikage Makoto、Tanizawa Yutaka、Bando Etsuro、Kanai Yae、Akiyama Yasuto、Yamaguchi Ken
    • Journal Title

      Gastric Cancer

      Volume: 25 Issue: 1 Pages: 138-148

    • DOI

      10.1007/s10120-021-01242-0

    • NAID

      40022799797

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-20K07649, KAKENHI-PROJECT-21K16476
  • [Journal Article] The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicine2021

    • Author(s)
      Hatanaka Yutaka、Kuwata Takeshi、Morii Eiichi、Kanai Yae、Ichikawa Hitoshi、Kubo Takashi、Hatanaka Kanako C.、Sakai Kazuko、Nishio Kazuto、Fujii Satoshi、Okamoto Wataru、Yoshino Takayuki、Ochiai Atsushi、Oda Yoshinao
    • Journal Title

      Pathology International

      Volume: 71 Issue: 11 Pages: 725-740

    • DOI

      10.1111/pin.13170

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Journal Article] Demarcated redness associated with increased vascular density/size: a useful marker of flat-type dysplasia in patients with ulcerative colitis2021

    • Author(s)
      Ikebata Akiyoshi、Shimoda Masayuki、Okabayashi Koji、Uraoka Toshio、Maehata Tadateru、Sugimoto Shinya、Mutaguchi Makoto、Naganuma Makoto、Kameyama Kaori、Yahagi Naohisa、Kanai Takanori、Kitagawa Yuko、Kanai Yae、Iwao Yasushi
    • Journal Title

      Endoscopy International Open

      Volume: 09 Issue: 04 Pages: E552-E561

    • DOI

      10.1055/a-1352-2709

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-20H03746
  • [Journal Article] Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities2021

    • Author(s)
      Tanaka Yosuke、Chiwaki Fumiko、Kojima Shinya、Kawazu Masahito、Komatsu Masayuki、Ueno Toshihide、Inoue Satoshi、Sekine Shigeki、Matsusaki Keisuke、Matsushita Hiromichi、Boku Narikazu、Kanai Yae、Yatabe Yasushi、Sasaki Hiroki、Mano Hiroyuki
    • Journal Title

      Nature Cancer

      Volume: 2 Issue: 9 Pages: 962-977

    • DOI

      10.1038/s43018-021-00240-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K12117
  • [Journal Article] Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling.2021

    • Author(s)
      Endo Y, Fujimoto M, Ito N, Takahashi Y, Kitago M, Gotoh M, Hiraoka N, Yoshida T, Kitagawa Y, Kanai Y, Arai E.
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 147 Issue: 5 Pages: 1341-1354

    • DOI

      10.1007/s00432-021-03541-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07444, KAKENHI-PROJECT-21H02705
  • [Journal Article] Steatotic and nonsteatotic scirrhous hepatocellular carcinomas reveal distinct Clinicopathological features.2019

    • Author(s)
      Hatano M, Ojima H, Masugi Y, Tsujikawa H, Hiraoka N, Kanai Y, Shimada K, Shinoda M, Sakamoto M.
    • Journal Title

      Hum Pathol

      Volume: 印刷中 Pages: 222-232

    • DOI

      10.1016/j.humpath.2018.11.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Journal Article] Genome-wide DNA methylation profile of early-onset endometrial cancer: Its correlation with genetic aberrations and comparison with late-onset endometrial cancer.2019

    • Author(s)
      Makabe T, Arai E, Hirano T, Ito N, Fukamachi Y, Takahashi Y, Hirasawa A, Yamagami W, Susumu N, Aoki D, Kanai Y.
    • Journal Title

      Carcinogenesis

      Volume: 印刷中 Issue: 5 Pages: 1-13

    • DOI

      10.1093/carcin/bgz046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-16K08720, KAKENHI-PROJECT-16K11156, KAKENHI-PROJECT-19K07444, KAKENHI-PROJECT-17K19611
  • [Journal Article] Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma.2019

    • Author(s)
      Saito Y, Muramatsu T, Kanai Y, Ojima H, Sukeda A, Hiraoka N, Arai E, Sugiyama Y, Matsuzaki J, Uchida R, Yoshikawa N, Furukawa R, Saito H.
    • Journal Title

      Cell Rep

      Volume: 27 Issue: 4 Pages: 1265-1276

    • DOI

      10.1016/j.celrep.2019.03.088

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08720, KAKENHI-PROJECT-19K07444, KAKENHI-PROJECT-19K22818, KAKENHI-PROJECT-17H03592
  • [Journal Article] Novel method for DNA methylation analysis using high-performance liquid chromatography and its clinical application.2018

    • Author(s)
      Yotani T, Yamada Y, Arai E, Tian Y, Gotoh M, Komiyama M, Fujimoto H, Sakamoto M, Kanai Y.
    • Journal Title

      Cancer Sci

      Volume: 109 Issue: 5 Pages: 1690-1700

    • DOI

      10.1111/cas.13566

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-16K08720
  • [Journal Article] Feasibility of methylome analysis using small amounts of genomic DNA from formalin-fixed paraffin-embedded tissue.2018

    • Author(s)
      Ohara K, Arai E, Takahashi Y, Fukamachi Y, Ito N, Maeshima AM, Fujimoto H, Yoshida T, Kanai Y.
    • Journal Title

      Pathol Int

      Volume: 68 Issue: 11 Pages: 633-635

    • DOI

      10.1111/pin.12716

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-16K08720
  • [Journal Article] Epigenome mapping of human normal purified hepatocytes: personal epigenome variation and genome-epigenome correlation.2018

    • Author(s)
      Arai E, Miura F, Totoki Y, Yamashita S, Tian Y, Gotoh M, Ojima H, Nakagawa H, Takahashi Y, Nakamura H, Hama N, Kato M, Kimura H, Suzuki Y, Ito T, Shibata T, Kanai Y.
    • Journal Title

      Epigenomics

      Volume: 10 Issue: 7 Pages: 955-979

    • DOI

      10.2217/epi-2017-0111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-16K08720
  • [Journal Article] The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: Standard operating procedures based on empirical analyses.2018

    • Author(s)
      Kanai Y, Nishihara H, Miyagi Y, Tsuruyama T, Taguchi K, Katoh H, Takeuchi T, Gotoh M, Kuramoto J, Arai E, Ojima H, Shibuya A, Yoshida T, Akahane T, Kasajima R, Morita KI, Inazawa J, Sasaki T, Fukayama M, Oda Y.
    • Journal Title

      Pathology International

      Volume: 68 Issue: 2 Pages: 63-90

    • DOI

      10.1111/pin.12631

    • NAID

      120007134466

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08720, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-16K14630, KAKENHI-PROJECT-16H02472
  • [Journal Article] Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system2018

    • Author(s)
      Saito Yoshimasa、Nakaoka Toshiaki、Muramatsu Toshihide、Ojima Hidenori、Sukeda Aoi、Sugiyama Yuko、Uchida Ryoei、Furukawa Ryo、Kitahara Aya、Sato Toshiro、Kanai Yae、Saito Hidetsugu
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 2821-2821

    • DOI

      10.1038/s41598-018-21121-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-17H03592, KAKENHI-PROJECT-15K09021, KAKENHI-PROJECT-16K13051, KAKENHI-PROJECT-16H02472
  • [Journal Article] Epigenome mapping of human normal purified hepatocytes: Personal epigenome variation and genome-epigenome correlation.2018

    • Author(s)
      Arai E, Miura F, Totoki Y, Yamashita S, Tian Y, Gotoh M, Ojima H, Nakagawa H, Takahashi Y, Nakamura H, Hama N, Kato M, Kimura H, Suzuki Y, Ito T, Shibata T, Kanai Y.
    • Journal Title

      Epigenomics

      Volume: 未定

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Journal Article] Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis.2017

    • Author(s)
      Kuramoto J, Arai E, Tian Y, Funahashi N, Hiramoto M, Nammo T, Nozaki Y, Takahashi Y, Ito N, Shibuya A, Ojima H, Sukeda A, Seki Y, Kasama K, Yasuda K, Kanai Y.
    • Journal Title

      Carcinogenesis.

      Volume: 38 Issue: 3 Pages: 261-270

    • DOI

      10.1093/carcin/bgx005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461352, KAKENHI-PROJECT-15K16537, KAKENHI-PROJECT-16K01850, KAKENHI-PROJECT-16K08720, KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-17K15668
  • [Journal Article] Cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids.2017

    • Author(s)
      Nakaoka T, Saito Y, Shimamoto Y, Muramatsu T, Kimura M, Kanai Y, Saito H.
    • Journal Title

      Cancer Sci,

      Volume: 108 Issue: 4 Pages: 678-684

    • DOI

      10.1111/cas.13165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-26290049, KAKENHI-PROJECT-15K09021, KAKENHI-PROJECT-16K13051, KAKENHI-PROJECT-17H03592
  • [Journal Article] Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis.2017

    • Author(s)
      Yamada S, Kamada N, Amiya T, Nakamoto N, Nakaoka T, Kimura M, Saito Y, Ejima C, Kanai T, Saito H.
    • Journal Title

      BMC Gastroenterology

      Volume: 17 Issue: 1 Pages: 136-136

    • DOI

      10.1186/s12876-017-0689-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03592, KAKENHI-PROJECT-15K09021, KAKENHI-PROJECT-16K13051
  • [Journal Article] Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: A single-institutional methylome analysis using 1007 tissue specimens.2017

    • Author(s)
      Ohara K, Arai E*, Takahashi Y, Ito N, Shibuya A, Tsuta K, Kushima R, Tsuda H, Ojima H, Fujimoto H, Watanabe S, Katai H, Kinoshita T, Shibata T, Kohno T, Kanai Y.
    • Journal Title

      Carcinogenesis

      Volume: 38 Pages: 241-251

    • DOI

      10.1093/carcin/bgw209

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08720, KAKENHI-PROJECT-16H02472
  • [Journal Article] Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.2016

    • Author(s)
      Saito Y, Nakaoka T, Sakai K, Muramatsu T, Toshimitsu K, Kimura M, Kanai T, Sato T, Saito H
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 25311-25311

    • DOI

      10.1038/srep25311

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26290049, KAKENHI-PROJECT-15K09021, KAKENHI-PROJECT-16K13051
  • [Journal Article] Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response2016

    • Author(s)
      Yoshimasa Saito, Toshiaki Nakaoka, Kasumi Sakai, Toshihide Muramatsu, Kohta Toshimitsu, Masaki Kimura, Takanori Kanai, Toshiro Sato, Hidetsugu Saito
    • Journal Title

      Scientific Reports

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26290049
  • [Journal Article] Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma.2016

    • Author(s)
      Saito K, Arai E, Maekawa K, Ishikawa M, Fujimoto H, Taguchi R, Matsumoto K, Kanai Y, Saito Y.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 28932-28932

    • DOI

      10.1038/srep28932

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-16K08720
  • [Journal Article] Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome.2015

    • Author(s)
      Yamanoi K, Arai E, Tian Y, Takahashi Y, Miyata S, Sasaki H, Chiwaki F, Ichikawa H, Sakamoto H, Kushima R, Katai H, Yoshida T, Sakamoto M, Kanai Y.
    • Journal Title

      Carcinogenesis

      Volume: 36 Issue: 5 Pages: 509-520

    • DOI

      10.1093/carcin/bgv013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-25460487
  • [Journal Article] First-line eradication for Helicobacter pylori-positive gastritis by esomeprazole-based triple therapy is influenced by CYP2C19 genotype.2015

    • Author(s)
      Saito Y, Serizawa H, Kato Y, Nakano M, Nakamura M, Saito H, Suzuki H, Kanai T.
    • Journal Title

      World J. Gastroenterol.

      Volume: 21 Issue: 48 Pages: 13548-54

    • DOI

      10.3748/wjg.v21.i48.13548

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670065, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-26290049
  • [Journal Article] Prognostication of patients with clear cell renal cell carcinomas based on quantification of DNA methylation levels of CpG island methylator phenotype marker genes.2014

    • Author(s)
      Tian Y, Arai E, Gotoh M, Komiyama M, Fujimoto H, Kanai Y.
    • Journal Title

      BMC Cancer

      Volume: 14 Issue: 1 Pages: 772-772

    • DOI

      10.1186/1471-2407-14-772

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-25460487
  • [Journal Article] Comprehensive exploration of novel chimeric transcripts in clear cell renal cell carcinomas using whole transcriptome analysis.2014

    • Author(s)
      Gotoh M, Ichikawa H, Arai E, Chiku S, Sakamoto H, Fujimoto H, Hiramoto M, Nammo T, Yasuda K, Yoshida T, Kanai Y.
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 53 Issue: 12 Pages: 1018-1032

    • DOI

      10.1002/gcc.22211

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-25460487, KAKENHI-PROJECT-26461352
  • [Journal Article] Multilayer-omics analyses of human cancers: Exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium.2014

    • Author(s)
      Kanai Y, Arai E.
    • Journal Title

      Front Genetics

      Volume: 5 Pages: 24-24

    • DOI

      10.3389/fgene.2014.00024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-25460487
  • [Journal Article] Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: its correlation with smoking history and chronic obstructive pulmonary disease.2014

    • Author(s)
      Sato T, Arai E, Kohno T, Takahashi Y, Miyata S, Tsuta K, Watanabe S, Soejima K, Betsuyaku T, Kanai Y.
    • Journal Title

      Int J Cancer

      Volume: in press Issue: 2 Pages: 319-334

    • DOI

      10.1002/ijc.28684

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-25460487
  • [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis.2014

    • Author(s)
      Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H.
    • Journal Title

      Cancer Sci.

      Volume: 105 Issue: 10 Pages: 1254-1260

    • DOI

      10.1111/cas.12498

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-25460487, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26290049, KAKENHI-PROJECT-221S0001
  • [Journal Article] The tumor suppressor microRNA -29c is downregulated and restored by celecoxib in human gastric cancer cells2013

    • Author(s)
      Saito Y, Suzuki H, Imaeda H, Matsuzaki J, et al.
    • Journal Title

      International Journal of Cancer

      Volume: 132 Issue: 8 Pages: 1751-1760

    • DOI

      10.1002/ijc.27862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06306, KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23680090, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25460173
  • [Journal Article] DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.2013

    • Author(s)
      Sato T, Arai E, Kohno T, Tsuta K, Watanabe S, Soejima K, Betsuyaku T, Kanai Y.
    • Journal Title

      PLOS One

      Volume: 8(3) Issue: 3 Pages: e59444-e59444

    • DOI

      10.1371/journal.pone.0059444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590870, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23790456, KAKENHI-PROJECT-25460487
  • [Journal Article] DNA methyltransferase 3B expression is associated with pooroutcome of stage I testicular seminoma2012

    • Author(s)
      Aral E, Kanai Y, et al
    • Journal Title

      Histopathology

      Volume: 60 Issue: 6B

    • DOI

      10.1111/j.1365-2559.2012.04174.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23790456
  • [Journal Article] Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas2012

    • Author(s)
      Arai E, Kanai Y, et al
    • Journal Title

      Carcinogenesis

      Volume: (In press)(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Journal Article] Higher-order chromatin regulation and differential gene expression in human TNF/LT locus in hepatocellular carcinoma cells2012

    • Author(s)
      Watanabe T.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 32 Issue: 8 Pages: 1529-1541

    • DOI

      10.1128/mcb.06478-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390055, KAKENHI-PROJECT-23390096, KAKENHI-PLANNED-23116009
  • [Journal Article] Diagnosis and prognostication of ductal adenocarcinomas of the pancreas based on genome-wide DNA methylation profiling by bacterial artificial chromosome array-based methylated CpG island amplification2011

    • Author(s)
      Gotoh M, Inazawa J, et al
    • Journal Title

      J Biomed Biotechnol

      Volume: 2011 Issue: 1 Pages: 780836-780836

    • DOI

      10.1155/2011/780836

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-22240090, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23790456
  • [Journal Article] Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage2011

    • Author(s)
      Nagashio R, Kondo Y, 6名
    • Journal Title

      Int J Cancer

      Volume: 129 Issue: 5 Pages: 1170-1179

    • DOI

      10.1002/ijc.26061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300344, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23790456
  • [Journal Article] Copy number alterations in urothelial carcinomas : Their clinicopathological significance and correlation with DNA methylation alterations2011

    • Author(s)
      Nishiyama N, Inazawa J, et al
    • Journal Title

      Carcinogenesis

      Volume: 32 Issue: 4 Pages: 462-469

    • DOI

      10.1093/carcin/bgq274

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-22240090, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23790456
  • [Journal Article] Genome-wide DNA methylation profiles in renal tumors of various histological subtypes and non-tumorous renal tissues2011

    • Author(s)
      Arai E, Inazawa J, et al
    • Journal Title

      Pathobiology

      Volume: 78 Issue: 1 Pages: 1-9

    • DOI

      10.1159/000322072

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-22240090, KAKENHI-PROJECT-23390096, KAKENHI-PROJECT-23390325, KAKENHI-PROJECT-23790456
  • [Journal Article] Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion.2007

    • Author(s)
      Sawada, M., Kanai, Y., Arai, E., Ushijima, S., Ojima, H., and Hirohashi, S.
    • Journal Title

      Cancer Lett 251

      Pages: 211-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Connective Tissue Growth Factor is a putative conditional tumor-suppressor gene frequently inactivated by promoter hypermethylation in ovarian cancer.2007

    • Author(s)
      Ryoko Kikuchi, Yae Kanai, et. al.
    • Journal Title

      Cancer Res (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion.2007

    • Author(s)
      Morio Sawada, Yae Kanai, et. al.
    • Journal Title

      Cancer Lett 251

      Pages: 211-219

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues.2006

    • Author(s)
      Arai, E., Kanai, Y., Ushijima, S., Fujimoto, H., Mukai, K., and Hirohashi, S.
    • Journal Title

      Int J Cancer 119

      Pages: 288-296

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Epigenetic instability and chromosomal instability in hepatocellular carcinoma.2006

    • Author(s)
      Katoh, H., Shibata, T., Kokubu, A., Ojima, H., Fukayama, M., Kanai, Y., and Hirohashi, S.
    • Journal Title

      Am J Pathol 168

      Pages: 1375-1384

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Epigenetic instability and chromosomal instability in hepatocellular carcinoma.2006

    • Author(s)
      Hiroto Katoh, Yae Kanai, et. al.
    • Journal Title

      Am J Pathol 168

      Pages: 1375-1384

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion.2006

    • Author(s)
      Morio Sawada, Yae Kanai, et al.
    • Journal Title

      Cancer Lett (in press)

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Promoter hypermethylation of the potential tumor suppressor DAL-1 /4. 1B gene in renal clear cell carcinoma. I2006

    • Author(s)
      Yamada, D., Kikuchi, S., Williams, Y.N., Sakurai-Yageta, M., Masuda, M., Maruyama, T., Tomita, K., Gutmann, D.H., Kakizoe, T., Kitamura, T., Kanai, Y., and Murakami, Y.
    • Journal Title

      Int J Cancer 118

      Pages: 916-923

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues.2006

    • Author(s)
      Eri Arai, Yae Kanai, et al.
    • Journal Title

      Int J Cancer 119

      Pages: 288-296

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA methylation of multiple tumor-related genes in association with overexpression of DNA methltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.2006

    • Author(s)
      Dun-Fa Peng, Yae Kanai, et al.
    • Journal Title

      Carcinogenesis 27

      Pages: 1160-1168

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma.2006

    • Author(s)
      Daisuke Yamada, Yae Kanai, et. al.
    • Journal Title

      Int J Cancer 118

      Pages: 916-923

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.2006

    • Author(s)
      Dun-Fa Peng, Yae Kanai, et. al.
    • Journal Title

      Carcinogenesis 27

      Pages: 1160-1168

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues.2006

    • Author(s)
      Eri Arai, Yae Kanai, et. al.
    • Journal Title

      Int J Cancer 119

      Pages: 288-296

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Epigenetic instability and chromosomal instability in hepatocellular carcinoma.2006

    • Author(s)
      Hiroto Katoh, Yae Kanai, et al.
    • Journal Title

      Am J Pathol 168

      Pages: 1375-1384

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma.2006

    • Author(s)
      Daisuke Yamada, Yae Kanai, et al.
    • Journal Title

      Int J Cancer 118

      Pages: 916-923

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.2006

    • Author(s)
      Peng, D.F., Kanai, Y., Sawada, M., Ushijima, S., Hiraoka, N., Kitazawa, S., and Hirohashi, S.
    • Journal Title

      Carcinogenesis 27

      Pages: 1160-1168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene.2005

    • Author(s)
      Chihara, Y., Kanai, Y., et al.
    • Journal Title

      Lab.Invest. in press

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Tohru Nakagawa, Yae Kanai, et. al.
    • Journal Title

      J Urol 173

      Pages: 243-246

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas.2005

    • Author(s)
      Peng, D.F., Kanai, Y., Sawada, M., Ushijima, S., Hiraoka, N., Kosuge, T., and Hirohashi, S.
    • Journal Title

      Cancer Sci 96

      Pages: 403-408

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene.2005

    • Author(s)
      Yoshitomo Chihara, Yae Kanai, et. al.
    • Journal Title

      Lab Invest 85

      Pages: 895-907

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.2005

    • Author(s)
      Tohru Nakagawa, Yae Kanai, et. al.
    • Journal Title

      J Urol 173

      Pages: 1767-1771

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., et al.
    • Journal Title

      J.Urol. 173

      Pages: 243-246

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., Ushijima, S., Kitamura, T., Kakizoe, T., and Hirohashi, S.
    • Journal Title

      J Urol 173

      Pages: 243-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression duiring multistage urothelial carcinogenesis.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., Ushijima, S., Kitamura, T., Kakizoe, T., Hirohashi, S.
    • Journal Title

      J Urol 173

      Pages: 1767-1771

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., et al.
    • Journal Title

      J.Urol. (in press)

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene.2005

    • Author(s)
      Chihara, Y., Sugano, K., Kobayashi, A., Kanai, Y., Yamamoto, H., Nakazono, M., Fujimoto, H., Kakizoe, T., Fujimoto, K., Hirohashi, S., and Hirao, Y.
    • Journal Title

      Lab Invest 85

      Pages: 895-907

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas.2005

    • Author(s)
      Dun-Fa Peng, Yae Kanai, et. al.
    • Journal Title

      Cancer Sci 96

      Pages: 403-408

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene.2005

    • Author(s)
      Chihara, Y., Kanai, Y., et al.
    • Journal Title

      Lab.Invest. (in press)

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., et al.
    • Journal Title

      J.Urol. 173

      Pages: 243-246

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.2005

    • Author(s)
      Nakagawa, T., Kanai, Y., et al.
    • Journal Title

      J.Urol. in press

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] Increased DNA methyltransferase 1(DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Etoh, T., Kanai, Y., Ushijima, S., Nakagawa, T., Nakanishi, Y., Sasako, M., Kitano, S., and Hirohashi, S.
    • Journal Title

      Am J Pathol 164

      Pages: 689-699

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.2004

    • Author(s)
      Nam, J.S., Ino, Y., Kanai, Y., Sakamoto, M., and Hirohashi, S.
    • Journal Title

      Clin Exp Metastasis 21

      Pages: 49-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis.2004

    • Author(s)
      Kanai Y., et al.
    • Journal Title

      J.Cancer Res.Clin.Oncol. 130

      Pages: 636-644

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis.2004

    • Author(s)
      Yae Kanai, et. al.
    • Journal Title

      J Cancer Res Clin Oncol 130

      Pages: 636-644

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hep atocarcmo genesis region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.2004

    • Author(s)
      Kanai, Y., Saito, Y., Ushijima, S., and Hirohashi, S.
    • Journal Title

      J Cancer Res Clin Oncol 130

      Pages: 636-644

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA metyl transferase 1(DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Etoh, T., Kanai, Y., et al.
    • Journal Title

      Am.J.Pathol. 164

      Pages: 689-699

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b,DNMT3b4,during human hepatocarcinogenesis.2004

    • Author(s)
      Kanai Y., et al.
    • Journal Title

      J.Cancer Res.Clin.Oncol. 130

      Pages: 636-644

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.2004

    • Author(s)
      Jeong-Seok Nam, Yae Kanai, et. al.
    • Journal Title

      Clin Exp Metastasis 21

      Pages: 49-56

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Etoh, T., Kanai, Y., et al.
    • Journal Title

      Am.J.Pathol. 164

      Pages: 689-699

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] 5-Aza-2'-deoxycytidine restroes the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.2004

    • Author(s)
      Nam, J-S, Kanai, Y., et al.
    • Journal Title

      Clin.Exp.Metas. 21

      Pages: 49-56

    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] 5-Aza-2'-deoxycytidine restroes the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.2004

    • Author(s)
      Nam, J-S, Kanai, Y., et al.
    • Journal Title

      Clin.Exp.Metas. 21

      Pages: 49-56

    • Data Source
      KAKENHI-PROJECT-16023272
  • [Journal Article] Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Tsuyoshi Etoh, Yae Kanai, et. al.
    • Journal Title

      Am J Pathol 164

      Pages: 689-699

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.2003

    • Author(s)
      Horikawa, Y., Sugano, K., Shigyo, M., Yamamoto, H., Nakazono, M., Fujimoto, H., Kanai, Y., Hirohashi, S., Kakizoe, T., Habuchi, T., and Kato, T.
    • Journal Title

      J Urol 169

      Pages: 1541-1545

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Mutation of the DNA methyltransferase (DNMT) 1 gene in human colorectal cancers.2003

    • Author(s)
      Yae Kanai, et. al.
    • Journal Title

      Cancer Lett 192

      Pages: 75-82

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Mutation of the DN A methyltransferase (DNMT) 1 gene in human colorectal cancers.2003

    • Author(s)
      Kanai, Y., Ushijima, S., Nakanishi, Y., Sakamoto, M., and Hirohashi, S.
    • Journal Title

      Cancer Lett 192

      Pages: 75-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder.2003

    • Author(s)
      Nakagawa, T., Kanai, Y., Saito, Y., Kitamura, T., Kakizoe, T., and Hirohashi, S.
    • Journal Title

      J Urol 170

      Pages: 2463-2466

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.2003

    • Author(s)
      Yoshimasa Saito, Yae Kanai, et. al.
    • Journal Title

      Int J Cancer 105

      Pages: 527-532

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder.2003

    • Author(s)
      Tohru Nakagawa, Yae Kanai, et. al.
    • Journal Title

      J Urol 170

      Pages: 2463-2466

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.2003

    • Author(s)
      Saito, Y., Kanai, Y., Nakagawa, T., Sakamoto, M., Saito, H., Ishii, H., and Hirohashi, S.
    • Journal Title

      Int J Cancer 105

      Pages: 527-532

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.2003

    • Author(s)
      Yohei Horikawa, Yae Kanai, et. al.
    • Journal Title

      J Urol 169

      Pages: 1541-1545

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Journal Article] Connective Tissue Growth Factor is a putative conditional tumor-suppressor gene frequently inactivated by promoter hypermethylation in ovarian cancer.

    • Author(s)
      Kikuchi, R., Tsuda, H., Kanai, Y., Kasamatsu, T., Sengoku, K., Hirohashi, S., Inazawa, J., and Imoto, I.
    • Journal Title

      Cancer Res

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390120
  • [Patent] 尿路上皮癌のリスク判定方法2019

    • Inventor(s)
      Kanai Yae, Arai Eri
    • Industrial Property Rights Holder
      Keio Univ, SEKISUI MEDICAL
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Patent] 子宮体癌の予後の判定方法2018

    • Inventor(s)
      金井弥栄・新井恵吏・青木大輔・進伸幸・山上亘・真壁健
    • Industrial Property Rights Holder
      学校法人慶應義塾・積水メディカル株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-228276
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Patent] 尿路上皮癌のリスクの判定方法2018

    • Inventor(s)
      金井弥栄, 新井恵吏
    • Industrial Property Rights Holder
      金井弥栄, 新井恵吏
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-051464
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Patent] 尿路上皮癌のリスク判定方法2018

    • Inventor(s)
      金井弥栄・新井恵吏
    • Industrial Property Rights Holder
      学校法人慶應義塾
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-051464
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Patent] Method for assessing risk of hepatocellular carcinoma2018

    • Inventor(s)
      Kanai, Yae, et al.
    • Industrial Property Rights Holder
      Natl Cancer Ctr, SEKISUI MEDICAL
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Patent] がん幹細胞集団の調製方法2014

    • Inventor(s)
      齋藤義正、齋藤英胤、佐藤俊朗、尾島英知、金井弥栄、村松俊英
    • Industrial Property Rights Holder
      慶應義塾
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-146144
    • Filing Date
      2014-07-16
    • Data Source
      KAKENHI-PROJECT-26290049
  • [Presentation] 教育講演2: 泌尿器がんにおけるエピゲノム異常の意義と臨床応用2023

    • Author(s)
      金井弥栄
    • Organizer
      第88回日本泌尿器科学会東部総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] DNA methylation diagnostics for upper urinary tract urothelial carcinoma using newly developed high-performance liquid chromatography2023

    • Author(s)
      Mao Fujimoto, Eri Arai, Takuya Kikushima, Naotaka Nishiyama, Tomofumi Nakamura, Yuriko Yamada, Hiroaki Taira, Takuya Yotani, Hiroshi Kitamura, Yae Kanaii
    • Organizer
      America Association for Cancer Research Annual Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 発がんエピゲノム機構にかかる分子病理学研究2023

    • Author(s)
      金井弥栄
    • Organizer
      第112回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 高速液体クロマトグラフィーによる DNAメチル化解析に基づく上部尿路がん新規非侵襲的診断法開発2023

    • Author(s)
      藤本真央、新井恵吏、菊島卓也、西山直隆、中村知史、山田有理子、太平博暁、與谷卓也、北村寛、金井弥栄
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 肺腺がんの DNAメチル化プロファイルに対する免疫微小環境の影響2023

    • Author(s)
      河原徹、藤本真央、下田将之、淺村尚生、金井弥栄、新井恵吏
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 日米の非アルコール性脂肪性肝炎由来肝細胞がんにおけるゲノム網羅的DNAメチル化解析2023

    • Author(s)
      藏本純子、新井恵吏、藤本真央、牧内里美、津田昇、安田和基、平岡伸介、吉田輝彦、Evason Kimberley、金井弥栄
    • Organizer
      第82回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 日米の非アルコール性脂肪性肝炎由来肝細胞がんにおけるゲノム網羅的DNAメチル化解析2023

    • Author(s)
      藏本純子、新井恵吏、藤本真央、牧内里美、津田昇、安田和基、平岡伸介、吉田輝彦、Evason Kimberley、金井弥栄
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 諸臓器の多段階発がん過程早期に普遍的なDNAメチル化プロファイル.2022

    • Author(s)
      中山雄二、新井恵吏、藤本真央、津田昇、牧内里美、田迎、藏本純子、金井弥栄.
    • Organizer
      第81回日日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 導性CRISPR/dCas9を用いたC19MC肝内胆管癌オルガノイドの分化における役割の解明.2022

    • Author(s)
      葉子祥、松崎潤太郎、及川千尋、金井弥栄、齋藤義正.
    • Organizer
      第81回日日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 非アルコール性脂肪性肝炎由来肝細胞がんにおけるSPHK1ならびにLTB遺伝子の DNAメチル化異常.2022

    • Author(s)
      津田昇、田迎、藤本真央、藏本純子、牧内里美、尾島英知、後藤政広、平岡伸介、吉田輝彦、金井弥栄、新井恵吏.
    • Organizer
      第81回日日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 非アルコール性脂肪性肝炎由来肝細胞がんの組織学的多様性に関わるDNAメチル化異常.2022

    • Author(s)
      津田昇、新井恵吏、藏本純子、田迎、牧内里美、尾島英知、高橋順子、平岡伸介、吉田輝彦、金井 弥栄.
    • Organizer
      第111回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] Quantification of DNA methylation for carcinogenic risk estimation in patients with non-alcoholic steatohepatitis.2022

    • Author(s)
      Junko Kuramoto, Eri Arai, Mao Fujimoto, Ying Tian, Yuriko Yamada, Takuya Yotani, Satomi Makiuchi, Noboru Tsuda, Hidenori Ojima, Moto Fukai, Yosuke Seki, Kazunori Kasama, Nobuaki Funahashi, Haruhide Udagawa, Takao Nammo, Kazuki Yasuda, Akinobu Taketomi, Tatsuya Kanto, Yae Kanai.
    • Organizer
      American Association for Cancer Research Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 肺腺がんのDNAメチル化プロファイルに対する免疫微小環境の影響.2022

    • Author(s)
      河原徹、藤本真央、下田将之、淺村尚生、金井弥栄、新井恵吏.
    • Organizer
      第81回日日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 全血由来DNAにおけるエピゲノム関連解析による淡明細胞型腎細胞がんの検出に有用なDNAメチル化バイオマーカー候補の同定.2022

    • Author(s)
      大桃秀樹、新井恵吏、吉田輝彦、金井弥栄、清水厚志.
    • Organizer
      第81回日日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] DNAメチル化状態を指標とする非アルコール性脂肪性肝炎からの肝発がんリスク予測.2022

    • Author(s)
      藏本純子、新井恵吏、藤本真央、田迎、牧内里美、津田昇、尾島英知、山田有理子、輿谷卓也、高橋順子、深井原、関洋介、笠間和典、舟橋伸昭、宇田川陽秀、南茂隆生、安田和基、武富紹信、考藤達哉、金井弥栄.
    • Organizer
      第111回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 個別化治療・予防を目指した病理組織検体におけるエピゲノム解析2021

    • Author(s)
      金井弥栄
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] Correlations between genome-wide DNA methylation profiles and genomic driver aberrations during multistage lung adenocarcinogenesis2021

    • Author(s)
      Kenichi Hamada, Ying Tian, Mao Fujimoto, Yoriko Takahashi, Takashi Kohno, Koji Tsuta, Shun-ichi Watanabe, Teruhiko Yoshida,Hisao Asamura, Yae Kanai, Eri Arai
    • Organizer
      American Association for Cancer Research Annual Meeting 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] がんの病理組織検体における多層オミックス統合解析2021

    • Author(s)
      金井弥栄
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 多段階発がん過程におけるエピゲノム解析: 病理形態から個別化医療開発へ2021

    • Author(s)
      金井弥栄
    • Organizer
      第110回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 非アルコール性脂肪性肝炎由来肝細胞がんの多段階発生過程におけるDNAメチル化異常2021

    • Author(s)
      金井弥栄
    • Organizer
      Diabetes Scientific Meeting 2021
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] 病理検体のゲノム・エピゲノム解析で見えるがんの本態: 個別化医療開発に向けて2021

    • Author(s)
      金井弥栄
    • Organizer
      千里ライフサイエンス新適塾「難病への挑戦」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02705
  • [Presentation] Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related hepatocarcinogenesis2019

    • Author(s)
      Ying Tian, Eri Arai, Junko Kuramoto, Satomi Makiuchi, Noboru Tsuda, Hidenori Ojima, Yukihiro Fukamachi, Yoriko Takahashi, Nobuyoshi Hiraoka, Teruhiko Yoshida, Yae Kanai
    • Organizer
      11th American Association for Cancer Research-Japanese Cancer Association Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 組織学的に特記すべき所見を示さない肝に発生する病因不明の肝細胞がんのエピゲノム異常2018

    • Author(s)
      牧内里美, 新井恵吏, 藏本純子, 田迎, 深町幸宏, 高橋順子, 平岡伸介, 吉田輝彦, 金井弥栄
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] Genome-wide DNA methylation analysis during nonalcoholic steatohepatitis-related multistage hepatocarcinogenesis: Comparison with hepatitis virus-related carcinogenesis2018

    • Author(s)
      Junko Kuramoto, Eri Arai, Ying Tian, Nobuaki Funahashi, Masaki Hiramoto, Takao Nammo, Yuichi Nozaki, Yoriko Takahashi, Nanako Ito, Ayako Shibuya, Hidenori Ojima, Aoi Sukeda, Yosuke Seki, Kazunori Kasama, Kazuki Yasuda, Yae Kanai
    • Organizer
      American Association for Cancer Research Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 病理組織検体のオミックス解析に見るがんの多様性2018

    • Author(s)
      金井弥栄
    • Organizer
      第50回日本臨床分子形態学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] ゲノム医療における病理組織検体取扱い2018

    • Author(s)
      金井弥栄
    • Organizer
      第3回日本肉腫学会・日本臨床肉腫学会合同年次総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] ゲノム研究・診療のための病理組織検体の取扱い―日本病理学会規程に基づいて2018

    • Author(s)
      金井弥栄
    • Organizer
      第32回関東臨床細胞学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 病理組織検体のエピゲノム等オミックス解析研究が明らかにするがんの多様性2018

    • Author(s)
      金井弥栄
    • Organizer
      第37回消化器病態生理勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 前がん段階から肝細胞がんに至るDNAメチル化異常2018

    • Author(s)
      金井弥栄
    • Organizer
      第106回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 肝炎ウイルス感染・アルコール多飲・脂肪肝を伴わない肝発がんのエピゲノム異常2018

    • Author(s)
      牧内里美, 新井恵吏, 藏本純子, 田迎, 深町幸宏, 高橋順子, 平岡伸介, 吉田輝彦, 金井弥栄
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] enome-wide DNA methylation analysis during nonalcoholic steatohepatitis-related multistage hepatocarcinogenesis: Comparison with hepatitis virus-related carcinogenesis,2018

    • Author(s)
      Kuramoto J, Arai E, Tian Y, Funahashi N, Hiramoto M, Nammo T, Nozaki Y, Takahashi Y, Ito N, Shibuya A, Ojima H, Sukeda A, Seki Y, Kasama K, Yasuda K, Kanai Y.
    • Organizer
      The 109th Annual Meeting of the American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 若年性子宮体がんのゲノム網羅的DNAメチル化プロファイル2018

    • Author(s)
      真壁健, 新井恵吏, 平沢晃, 山上 亘, 進伸幸, 青木大輔, 金井弥栄
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] ゲノム・エピゲノム統合解析による胃発がん分子機構の解明2018

    • Author(s)
      楊夢晗, 新井恵吏, 坂本裕美, 戸塚裕彦, 谷口浩和, 吉田輝彦, 金井弥栄
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] ヒト多段階発がんのエピゲノム機構に関する分子病理学的研究2018

    • Author(s)
      金井弥栄
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] がんにおけるエピゲノム解析とその臨床展開2017

    • Author(s)
      金井弥栄
    • Organizer
      第44回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 発がん過程におけるエピゲノム解析を中心とした多層オミックス統合解析2017

    • Author(s)
      金井弥栄
    • Organizer
      第17回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] がん細胞の形態異常とゲノム・エピゲノム変化2017

    • Author(s)
      金井弥栄
    • Organizer
      第106回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 病理組織検体に見出されるDNAメチル化異常2017

    • Author(s)
      金井弥栄
    • Organizer
      第106回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 病理組織検体におけるエピゲノム等オミックス解析による個別化医療開発2017

    • Author(s)
      金井弥栄
    • Organizer
      生命化学系学会合同年会ConBio2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 肝発がんのエピゲノム機構2016

    • Author(s)
      金井弥栄
    • Organizer
      第57回日本臨床細胞学会総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2016-05-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 肝発がん過程におけるエピゲノム解析2016

    • Author(s)
      金井弥栄
    • Organizer
      第12回肝免疫・ウイルス・フロンティア
    • Place of Presentation
      ソラシティカンファレンスセンター (東京都千代田区)
    • Year and Date
      2016-04-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 個別化医療を目指したゲノム研究用病理組織検体取扱いの標準化2016

    • Author(s)
      金井弥栄
    • Organizer
      第 75 回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2016-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02472
  • [Presentation] 多層的疾患オミックス解析におけるエピゲノム情報に基づく創薬標的の網羅的探索を目指した研究2015

    • Author(s)
      金井弥栄
    • Organizer
      彩都産学官連携フォーラム2015
    • Place of Presentation
      大阪
    • Year and Date
      2015-01-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] バイオバンク試料の利活用: 組織検体における多層オミックス解析.2014

    • Author(s)
      金井弥栄
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 国際ヒトエピゲノムコンソーシアム (IHEC)における正常消化器上皮細胞等標準エピゲノムプロファイル決定2014

    • Author(s)
      金井弥栄
    • Organizer
      第59回日本人類遺伝学会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Epigenome mapping of normal hepatocytes for understanding molecular background of human hepatocarcinogenesis.2014

    • Author(s)
      Yae Kanai.
    • Organizer
      International Human Epigenome Consortium 2014
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2014-10-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 病理診断に付加価値を加える: 多層的オミックス解析にもとづく病態診断2014

    • Author(s)
      金井弥栄
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Multilayer-omics (whole-exome, methylome and transcriptome) analysis identifies the Wnt/β-catenin pathway as a key player in the development of renal cell carcinoma.2013

    • Author(s)
      Arai E, Sakamoto H, Ichikawa H, Totsuka H, Gotoh M, Mori T, Ohnami S, Nakagawa T, Fujimoto H, Wang L, Aburatani H, Yoshida T, and Kanai Y.
    • Organizer
      103rd American Association of Cancer Research Annual Meeting 2013
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Epigenome profiling during multistage human carcinogenesis and activities of International Human Epigenome Consortium (IHEC).2013

    • Author(s)
      Kanai Y
    • Organizer
      2013 Illumina Scientific Summit
    • Place of Presentation
      Phuket, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 国際ヒトエピゲノムコンソーシアムの取り組み.2013

    • Author(s)
      金井弥栄
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜311+312号室
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] DNA methylation profiles at precancerous stage cluster lung adenocarcinomas into subclusters associated with carcinogenetic pathway, clinicopathological aggressiveness and patient outcome.2013

    • Author(s)
      Sato T, Arai E, Kohno T, Tsuta K, Watanabe S, Soejima K, Betsuyaku T and Kanai Y.
    • Organizer
      103rd American Association of Cancer Research Annual Meeting 2013
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] がんにおけるエピゲノム変化の解明と病態診断への応用.2013

    • Author(s)
      金井弥栄
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      北海道札幌市ロイトン札幌ロイトンホールD
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 肺多段階発がん過程におけるDNAメチル化の変化のゲノム網羅的解析2012

    • Author(s)
      佐藤崇、金井弥栄, 他
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-27
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 多層的オミックス解析による疾患の本態解明と臨床応用シンポジウム2「オミックス解析と病理学」2012

    • Author(s)
      金井弥栄
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2012-04-27
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] ゲノム網羅的DNAメチル化解析による腎淡明細胞がんのCpGアイランドメチル化形質2012

    • Author(s)
      新井恵吏、金井弥栄, 他
    • Organizer
      第6回日本エピジェネティクス研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-15
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 肺多段階発がん過程におけるDNAメチル化異常のゲノム網羅的解析2012

    • Author(s)
      佐藤崇、金井弥栄, 他
    • Organizer
      第6回日本エピジェネティクス研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-15
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 腎細胞がん発生過程におけるDNAメチル化異常の網羅的解析2011

    • Author(s)
      新井恵吏、金井弥栄, 他
    • Organizer
      第5回日本エピジェネティクス研究会年会
    • Place of Presentation
      熊本
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Activation of the tumor suppressor microRNA-29cby the selective cyclooxygenase-2 inhibitor, celecoxib in human gastric cancer.2011

    • Author(s)
      Suzuki, H., Saito, Y., Kanai, Y., et al
    • Organizer
      AGA Research Forum DDW2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-09
    • Data Source
      KAKENHI-PROJECT-22300169
  • [Presentation] 泌尿器系腫瘍及びその背景組織のメチル化解析.ワークショップ1前癌病変及び背景粘膜におけるエピジェネティックス異常2011

    • Author(s)
      新井恵吏、金井弥栄
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜(招待講演)
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 腎細胞がん発生過程におけるDNAメチル化異常の網羅的解析2011

    • Author(s)
      新井恵吏、金井弥栄, 他
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 慢性障害肝におけるDNAメチル化状態を指標とした発がんリスク評価の肝生検検体を用いた臨床応用2011

    • Author(s)
      長塩亮、金井弥栄, 他
    • Organizer
      第5回日本エピジェネティクス研究会年会
    • Place of Presentation
      熊本
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Copy number alterations in urothelial carcinomas : Their clinicopathological significance and correlation with DNA methylation alterations2011

    • Author(s)
      Naotaka Nishiyama, Yae Kanai, et al
    • Organizer
      American Association for Cancer Research, 102nd Annual Meeting
    • Place of Presentation
      オーランド(米国)
    • Year and Date
      2011-04-05
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Upregulation of oncogenic microRNA-21followed by the downregulation of the tumor suppressor microRNA-29cin the progression of human gastric cancer.2010

    • Author(s)
      Suzuki, H., Saito, Y., Kanai, Y., et al
    • Organizer
      UEGW2010
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-10-25
    • Data Source
      KAKENHI-PROJECT-22300169
  • [Presentation] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from nonalcoholic steatohepatitis

    • Author(s)
      Saito Y, Takaki Y, Toshimitsu K, Takasugi A, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Kanai T, Saito H.
    • Organizer
      United European Gastroenterology Week 2014
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2014-10-20 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26290049
  • [Presentation] Epigenome profiling during multistage human carcinogenesis and activities of International Human Epigenome Consortium (IHEC).

    • Author(s)
      Yae Kanai.
    • Organizer
      2013 Illumina Scientific Summit
    • Place of Presentation
      Phuket, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas.

    • Author(s)
      Eri Arai, Yae Kanai 他.
    • Organizer
      9th American Association of Cancer Research-Japanese Cancer Association Joint Conference
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 多層的オミックス解析による疾患の本態解明と臨床応用. シンポジウム2「オミックス解析と病理学」

    • Author(s)
      金井弥栄.
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Standard epigenome analysis in digestive organs and research applications to multistage hepatocarcinogenesis.

    • Author(s)
      Yae Kanai 他.
    • Organizer
      International Human Epigenome Consortium 2012
    • Place of Presentation
      Soul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 肺多段階発がん過程におけるDNAメチル化異常のゲノム網羅的解析.

    • Author(s)
      佐藤崇、金井弥栄 他.
    • Organizer
      第6回日本エピジェネティクス研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 腎淡明細胞がんにおける多層的オミックス(エクソーム・メチローム・トランスクリプトーム)解析.

    • Author(s)
      新井恵吏、金井弥栄 他.
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Multilayer-omics (whole-exome, methylome and transcriptome) analysis identifies the Wnt/β-catenin pathway as a key player in the development of renal cell carcinoma.

    • Author(s)
      Eri Arai, Yae Kanai 他.
    • Organizer
      103rd American Association of Cancer Research Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] Suppression of Intestinal Tumor-Initiating Cells by Inhibition of DNA Methylation

    • Author(s)
      Saito Y, Sakai K, Toshimitsu K, Muramatsu T, Kimura M, Sato T, Kanai T, Saito H
    • Organizer
      United European Gastroenterology Week 2014
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2014-10-20 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26290049
  • [Presentation] Epigenome profiling during multistage hepatocarcinogenesis and activities of International Human Epigenome Consortium (IHEC).

    • Author(s)
      Yae Kanai.
    • Organizer
      17th Japan-Korea Cancer Research Workshop
    • Place of Presentation
      Busan, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 肺多段階発がん過程におけるDNAメチル化の変化のゲノム網羅的解析.

    • Author(s)
      佐藤崇、金井弥栄 他.
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] ゲノム網羅的DNAメチル化解析による腎淡明細胞がんのCpGアイランドメチル化形質.

    • Author(s)
      新井恵吏、金井弥栄 他.
    • Organizer
      第6回日本エピジェネティクス研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] DNA methylation profiles at precancerous stage cluster lung adenocarcinomas into subclusters associated with carcinogenetic pathway, clinicopathological aggressiveness and patient outcome.

    • Author(s)
      Takashi Sato, Yae Kanai 他.
    • Organizer
      103rd American Association of Cancer Research Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 尿路上皮がんにおけるゲノム構造異常:臨床病理学的意義ならびにDNAメチル化異常との関係.

    • Author(s)
      西山直隆、金井弥栄 他.
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] 前がん段階におけるDNAメチル化異常が肺腺がんの悪性度と予後を規定する.

    • Author(s)
      佐藤崇、金井弥栄 他.
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390096
  • [Presentation] DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.

    • Author(s)
      Takashi Sato, Yae Kanai 他.
    • Organizer
      9th American Association of Cancer Research-Japanese Cancer Association Joint Conference
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23390096
  • []

  • []

  • 1.  SAITO Yoshimasa (90360114)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 2.  ARAI Eri (40446547)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 52 results
  • 3.  SAKAMOTO Michiie (40221270)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OCHIAI Atsushi (60183034)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SATO Toshiro (70365245)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 6.  Nishiyama Naotaka (70619030)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  北村 寛 (00404674)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Hidekazu (70255454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  AKAIKE Toshihiro (30101207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ONISHI Yasuyuki (70201382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIROHASHI Setsuo (70129625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YAMADA Tesshi (30221659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TSUDA Hitoshi (70217321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAKANISHI Hiroyuki (10260316)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MAESHIMA Akiko (90342906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OOE Tomoyuki (30624283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAMOTO Naoki (40513289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  野口 雅之 (00198582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  山地 太樹 (10466203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  伊藤 秀美 (90393123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 21.  鈴木 拓 (20381254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  榊原 康文 (10287427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  小林 恭 (00642406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  YOSHIDA Teruhiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 25.  GOTOH Masahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 26.  YOSHIDA Kazunari
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  YASUDA Kazuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  OHARA Kentaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  SATO Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  稲澤 譲治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 31.  佐々木 光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  下田 将之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 33.  南茂 隆生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  谷田部 恭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  近藤 豊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  斎藤 英胤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  副島 研造
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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