HIROSE Kenzo 廣瀬謙造

Researcher Number	00292730
Other IDs
Affiliation *help	2016 – 2017 : 東京大学, 大学院医学系研究科(医学部), 教授 2012 – 2016 : 東京大学, 医学(系)研究科(研究院), 教授 2016 : 東京大学, 大学院医学系研究科, 教授 2014 : 東京大学, 大学院医学系研究科, 教授 2010 : 東京大学, 大学院・医学研究科, 教授 … More
Review Section/Research Field	Principal Investigator General pharmacology / General pharmacology / Biological Sciences / General physiology / Neurochemistry/Neuropharmacology Except Principal Investigator Biological Sciences / General pharmacology / General internal medicine (including Psychosomatic medicine) / 医薬分子機能学 / General physiology
Keywords	Principal Investigator カルシウム / イノシトール三リン酸 / シナプス / Inositol trisphosphate / 中枢神経 / cerebellum / プルキンエ細胞 / LTD / 小脳 / calcium … More Except Principal Investigator 精神疾患 / ミオシン / イメージング / シナプス / 躁うつ病 / 制御 / ダイニン / o-Nitrobenzyl基 / 双極性障害 / 消化管 / 電荷分離状態 / 細胞内マグネシウム / 超解像イメージング / マイクロエンドフェノタイプ / Nitrobenzyl group / カルシウム / 光誘起電子移動 / タンパク質分子 / ATP / グルタミン酸イメージング / Confocal fluorescence microscope / 数理モデル / 一酸化窒素 / 統合失調症 / 高ストレス社会 / マグネシウム / caged化合物 / Marcus理論 / モーター / イノシトール三リン酸 / レーザーフラッシュフォトリシス / 気分障害 / Marcus theory / 精神病態 / システム解析 / 共焦点顕微鏡 / マイクロエンドフェアタイプ / グルタミン酸 / リシ酸化 / PTSD / 心筋 / Photo-functional molecule / プルキンエ細胞 / 神経科学科学 / 膜輸送 / ニトロベンジル基 / キネシン / 細胞 / 蛍光イメージング / リン酸化 / 脳・神経 / 自閉症 / 計算化学 / 光機能性分子 / o-nitrobenzyl基 / 神経科学 / NFAT / ナノシステム / 血管 / うつ病 / フルオレセイン / 超高齢化 / Photoinduced Electron Tranfer / 7-ヒドロキシクマリン / Fluorescein / 生体ナノシステム / マグネシウム輸送体 / 7 -Hydroxycoumarin / Caged compounds / マグネシウム透過チャネル / Cajal細胞 Less

中枢カテコラミンの蛍光イメージング技術の開発Principal InvestigatorOngoing
- Principal Investigator
  
  廣瀬謙造
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
tudy of pathological mechanism underlying autism by focusing on nanoscale distribution of synaptic molecules
- Principal Investigator
  
  Namiki Shigeyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Unraveling the micro-endophenotypes of psychiatric disorders at the molecular, cellular and circuit levels
- Principal Investigator
  
  Kida Satoshi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Agriculture
Transformation of the relationship between synaptic supramolecular assemblies and synaptic function in mental disorderPrincipal Investigator
- Principal Investigator
  
  HIROSE Kenzo
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of dynamics of synaptically released glutamate in cortical neurons
- Principal Investigator
  
  NAMIKI Shigeyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Investigation of signal correlation and integration in ICC pacemaking
- Principal Investigator
  
  NAKAYAMA Shinsuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya University
Visualization analysis of spatiotemporal dynamics of glutamate in central nervous systemPrincipal Investigator
- Principal Investigator
  
  HIROSE Kenzo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
長期増強現象を担うPDZドメイン含有蛋白質の網羅的分子スクリーニング法の開発Principal Investigator
- Principal Investigator
  
  廣瀬謙造
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
Regulation of intracellular magnesium concentration
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
大規模RNAiライブラリーを用いたカルシウム流入分子機構の網羅的探索Principal Investigator
- Principal Investigator
  
  廣瀬謙造
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Regulation of Bio-nanosystems
- Principal Investigator
  
  HIGUCHI Hideo
- Project Period (FY)
  2004 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tohoku University
Integration of intracellular nanosystems in calcium signalingPrincipal Investigator
- Principal Investigator
  
  HIROSE Kenzo
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
  The University of Tokyo
味細胞内情報伝達のin situイメージング法による甘味感知の分子機構の解明Principal Investigator
- Principal Investigator
  
  廣瀬謙造
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
LTD and spatio-temporal dynamics of IP_3 within cerebellar Purkinje cellsPrincipal Investigator
- Principal Investigator
  
  HIROSE Kenzo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Role of IP_3 in LTD in cerebellar purkinje cellsPrincipal Investigator
- Principal Investigator
  
  HIRASE Kenzo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Development of novel caged compounds that can report the yield of uncaged products
- Principal Investigator
  
  URANO Yasuteru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
細胞内シグナルフローの可視化解析
- Principal Investigator
  
  飯野正光
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
リアルタイム可視化によるプレクストリン相同ドメインの機能解析Principal Investigator
- Principal Investigator
  
  廣瀬謙造
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Spatiotemporal Control of Receptor Tyrosine Kinase Activity by Caged Ligands.2015
- Author(s)
  Isa M, Namiki S, Asanuma D, Hirose K.
- Journal Title
  
  Chemistry Letters.
  
  Volume : 44 Pages : 150-1
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116004, KAKENHI-PROJECT-24590313, KAKENHI-PUBLICLY-25115704, KAKENHI-PROJECT-26560441
[Journal Article] High-throughput screening system to identify small molecules that induce internalization and degradation of HER2.2014
- Author(s)
  Isa M, Asanuma D, Namiki S, Kumagai K, Kojima H, Okabe T, Nagano T, Hirose K.
- Journal Title
  
  ACS Chemical Biology.
  
  Volume : 9 Pages : 2237-41
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116004, KAKENHI-PROJECT-24590313, KAKENHI-PUBLICLY-25115704, KAKENHI-PROJECT-26560441
[Journal Article] Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells.2014
- Author(s)
  Ishino Y, Hayashi Y, Naruse M, Tomita K, Sanbo M, Fuchigami T, Fujiki R, Hirose K, Toyooka Y, Fujimori T, Ikenaka K, Hitoshi S.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume : 34 Pages : 3067-78
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21116005, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-24300136, KAKENHI-PUBLICLY-25123706, KAKENHI-PROJECT-25650005, KAKENHI-PROJECT-26460298
[Journal Article] Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures.2014
- Author(s)
  Naoko H. Tomioka, Hiroki Yasuda, Hiroyuki Miyamoto, Minoru Hatayama, Naoko Morimura, Yoshifumi Matsumoto, Toshimitsu Suzuki, Maya Odagawa, Yuri S. Odaka, Yoshimi Iwayama, Ji Won Um, Jaewon Ko, Yushi Inoue, Sunao Kaneko, Shinichi Hirose, Kazuyuki Yamada, Takeo Yoshikawa, Kazuhiro Yamakawa, Jun Aruga
- Journal Title
  
  Nature Communications
  
  Volume : 5 Pages : 45011-16
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23500461, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-24249060, KAKENHI-PROJECT-24621012, KAKENHI-PUBLICLY-25110736, KAKENHI-PUBLICLY-25129708, KAKENHI-PROJECT-25640026, KAKENHI-PROJECT-25670481, KAKENHI-PROJECT-26430003
[Journal Article] High-throughput development of a hybrid-type fluorescent glutamate sensor for analysis of synaptic transmission.2014
- Author(s)
  Takikawa K, Asanuma D, Namiki S, Sakamoto H, Ariyoshi T, Kimpara N, Hirose K.
- Journal Title
  
  Angewandte Chemie International Edition.
  
  Volume : 53 Pages : 13439-43
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116004, KAKENHI-PROJECT-24590313, KAKENHI-PUBLICLY-25115704, KAKENHI-PROJECT-26560441, KAKENHI-PROJECT-14J06241
[Journal Article] Acidic-pH-activatable fluorescence probes for visualizing exocytosis dynamics.2014
- Author(s)
  Asanuma D, Takaoka Y, Namiki S, Takikawa K, Kamiya M, Nagano T, Urano Y, Hirose K.
- Journal Title
  
  Angewandte Chemie International Edition.
  
  Volume : 53 Pages : 6085-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116004, KAKENHI-PROJECT-24590313, KAKENHI-PUBLICLY-25115704
[Journal Article] Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury2013
- Author(s)
  Kanemaru, K., Kubota, J., Sekiya, H., Hirose, K., Okubo, Y. and Iino, M
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume : 110 Pages : 11612-11617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229004, KAKENHI-PROJECT-23689015, KAKENHI-PLANNED-24116004, KAKENHI-PROJECT-24700316
[Journal Article] Microelectrode array evaluation of gut pacemaker activity in wild-type and W/Wv mice2009
- Author(s)
  Nakayama S, Ohishi R, Sawamura K, Watanabe K. & Hirose K
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume : 25 Pages : 61-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390198
[Journal Article] Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer2008
- Author(s)
  Yogo T, Urano Y, Mizushima A, Sunahara H, Inoue T, Hirose K, Iino M, Kikuchi K, Nagano T.
- Journal Title
  
  PNAS 105
  
  Pages : 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Regulation of neurite growth by spontaneous Ca2+ oscillations in astrocytes2007
- Author(s)
  Kanemaru K, Okubo Y, Hirose K, Iino M.
- Journal Title
  
  J Neurosci 27
  
  Pages : 8957-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Optical glutamate sensor for spatiotemporal analysis of synaptic transmission2007
- Author(s)
  Namiki S, Sakamoto H, Iinuma S, Iino M, Hirose K
- Journal Title
  
  Eur J Neurosci 25
  
  Pages : 2249-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390063
[Journal Article] Ca2+ lightning conveys cell-cell contact information inside the cells.2006
- Author(s)
  Hashido M, Hayashi K, Hirose K, Iino M
- Journal Title
  
  EMBO Report 7
  
  Pages : 1117-1123
- Data Source
  KAKENHI-PROJECT-17689011
[Journal Article] Ca2+ lightning conveys cell-cell contact information inside the cells2006
- Author(s)
  Hashido, M., Hayashi, K., Hirose, K., Iino, M.
- Journal Title
  
  EMBO Rep. 7
  
  Pages : 1117-1123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations2006
- Author(s)
  Ishii, K., Hirose, K., Iino, M.
- Journal Title
  
  EMBO Rep. 7
  
  Pages : 390-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations2006
- Author(s)
  Ishii K, Hirose K, Iino M.
- Journal Title
  
  EMBO Report (印刷中)(電子出版:1月13日)
- Data Source
  KAKENHI-PROJECT-17689011
[Journal Article] Ca2+ lightning conveys cell-cell contact information inside the cells.2006
- Author(s)
  Hashido M, Hayashi K, Hirose K, Iino M
- Journal Title
  
  EMBO Report 7
  
  Pages : 1117-1123
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations2006
- Author(s)
  Ishii K, Hirose K, Iino M.
- Journal Title
  
  EMBO Report
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Evolution of fluorescein as a platform for finely tunable fluorescence probes2005
- Author(s)
  Urano, Y., Kamiya, M., Kanda, K., Ueno, T., Hirose, K., Nagano, T.
- Journal Title
  
  J Am Chem Soc. 127
  
  Pages : 4888-4894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] NO signalling decodes frequency of neuronal activity and generates synapse-specific plasticity in mouse cerebellum2005
- Author(s)
  Namiki S, Kakizawa S, Hirose K, Iino M.
- Journal Title
  
  J Physiol 566
  
  Pages : 849-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Real-time imaging of myosin II regulatory light chain phosphorylation using a new protein biosensor2005
- Author(s)
  Yamada, A., Hirose, K., Hashimoto, A., Iino, M.
- Journal Title
  
  Biochem. J. 385
  
  Pages : 589-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis2005
- Author(s)
  Hashimoto A, Hirose K, Iino M.
- Journal Title
  
  J Biol Chem. 280
  
  Pages : 26225-26232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Real-time imaging of myosin II regulatory light chain phosphorylation using a new protein biosensor.2005
- Author(s)
  Yamada, A., Hirose, K., Hashimoto, A., Iino, M.
- Journal Title
  
  Biochem.J. 385
  
  Pages : 589-594
- Data Source
  KAKENHI-PROJECT-15650069
[Journal Article] Real-time imaging of myosin II regulatory light chain phosphorylation using a new protein biosensor.2005
- Author(s)
  Yamada, A., Hirose, K., Hashimoto, A., Iino, M.
- Journal Title
  
  Biochem.J. 385
  
  Pages : 589-594
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.2005
- Author(s)
  Hashimoto A, Hirose K, Iino M.
- Journal Title
  
  J Biol Chem. 280
  
  Pages : 26225-26232
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] NO signalling decodes frequency of neuronal activity and generates synapse-specific plasticity in mouse cerebellum2005
- Author(s)
  Shigeyuki Namiki, Sho Kakizawa, Kenzo Hirose, Masamitsu Iino
- Journal Title
  
  The Journal of Physiology 566
  
  Pages : 849-863
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Evolution of Fluorescein as a Platform for Finely Tunable Fluorescence Probes2005
- Author(s)
  Yasuteru Urano, Mako Kamiya, Kojiro Kanda, Tasuku Ueno, Kenzo Hirose, Tetsuo Nagano
- Journal Title
  
  J.Am.Chem.Soc. (印刷中)
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Cross talk between metabotropic and ionotropic glutamate receptor-mediated signaling in parallel fiber-induced inositol 1, 4, 5-trisphosphate production in cerebellar Purkinje cells2004
- Author(s)
  Okubo, Y., Kakizawa, S., Hirose, K., Iino, M.
- Journal Title
  
  J Neurosci 24
  
  Pages : 9513-9520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Photo-acceleration of protein release from endosome in the protein transduction system2004
- Author(s)
  Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H.
- Journal Title
  
  FEBS Lett. 572
  
  Pages : 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1, 4, 5-triphosphate receptor using membrane-permeant probes2004
- Author(s)
  Yogo, T., Kikuchi, K., Inoue, T., Hirose, K., Iino, M., Nagano, T.
- Journal Title
  
  Chemistry & Biology 11
  
  Pages : 1053-1058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.2004
- Author(s)
  Yogo T, Kikuchi K, Inoue T, Hirose K, Iino M, Nagano T.
- Journal Title
  
  Chem.Biol. 11
  
  Pages : 1053-1058
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Cross talk between metabotropic and ionotropic glutamate receptor-mediated signaling in parallel fiber-induced inositol 1,4,5-trisphosphate production in cerebellar Purkinje cells.2004
- Author(s)
  Okubo Y, Kakizawa S, Hirose K, Iino M.
- Journal Title
  
  J.Neurosci. 24
  
  Pages : 9513-9520
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Photo-acceleration of protein release from endosome in the protein transduction system.2004
- Author(s)
  Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H.
- Journal Title
  
  FEBS Lett. 572
  
  Pages : 221-226
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.2004
- Author(s)
  Yogo T, Kikuchi K, Inoue T, Hirose K, _Iino M, Nagano T.
- Journal Title
  
  Chem.Biol. 11
  
  Pages : 1053-1058
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Cross talk between metabotropic and ionotropic glutamate receptor-mediated signaling in parallel fiber-induced inositol 1,4,5-trisphosphate production in cerebellar Purkinje cells.2004
- Author(s)
  Okubo Y, Kakizawa S, Hirose K, Iino M.
- Journal Title
  
  J.Neurosci. 24
  
  Pages : 9513-9520
- Data Source
  KAKENHI-PROJECT-16083206
[Journal Article] Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.2004
- Author(s)
  Yogo T, Kikuchi K, Inoue T, Hirose K, Iino M, Nagano T.
- Journal Title
  
  Chem.Biol. 11
  
  Pages : 1053-1058
- Data Source
  KAKENHI-PROJECT-15650069
[Journal Article] Photo-acceleration of protein release from endosome in the protein transduction system.2004
- Author(s)
  Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H.
- Journal Title
  
  FEBS Lett. 572
  
  Pages : 221-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Cross Talk between Metabotropic and Ionotropic Glutamate Receptor-Mediated Signaling in Parallel Fiber-Induced Inositol 1,4,5-Trisphosphate Production in Cerebellar Purkinje Cells.2004
- Author(s)
  Okubo, Y., Kakizawa, S., Hirose, K., Iino, M.
- Journal Title
  
  J.Neurosci. 24
  
  Pages : 9513-9520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Real-time fluorescence imaging of cellular function.2004
- Author(s)
  Hirose, K.
- Journal Title
  
  Microscopy. 39
  
  Pages : 190-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] RNAi library derived from cDNAs.2004
- Author(s)
  Hirose, K.
- Journal Title
  
  Jikkenigaku. 22
  
  Pages : 1413-1417
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Isoform-specific Phosphorylation of Metabotropic Glutamate Receptor 5 by Protein Kinase C (PKC) Blocks Ca^<2+> Oscillation and Oscillatory Translocation of Ca^<2+>-dependent PKC.2004
- Author(s)
  Uchino, M., Sakai, N., Kashiwagi, K., Shirai, Y., Shinohara, Y., Hirose, K., Iino, M., Yamamura, T., Saito, N.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages : 2254-2261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Modification of Intracellular Ca^<2+> Dynamics by Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptor Using Membrane-Permeant Probes.2004
- Author(s)
  Yogo, T., Kikuchi, K., Inoue, T., Hirose, K., Iino, M., Nagano, T.
- Journal Title
  
  Chem.Biol. 11
  
  Pages : 1053-1058
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Enzymatic production of RNAi libraries from cDNAs.2004
- Author(s)
  Shirane, D., Sugao, K., Namiki, S., Tanabe, M., Iino, M., Hirose, K.
- Journal Title
  
  Nature Genet. 36
  
  Pages : 190-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] EPRIL法-cDNAを原料としてRNAiライブラリーをつくる2004
- Author(s)
  Hirose, K
- Journal Title
  
  実験医学 22
  
  Pages : 1413-1417
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] 細胞機能のリアルタイム蛍光イメージング2004
- Author(s)
  Hirose, K
- Journal Title
  
  日本顕微鏡学会和文誌「顕微鏡」 39
  
  Pages : 190-192
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Intracellular delivery of glutathione S-transferase into mammalian cells.2003
- Author(s)
  Namiki, S., Tomida, T., Tanabe, M., Iino, M., Hirose, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 305
  
  Pages : 592-597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] NFAT functions as a working memory of Ca^<2+> signals in decoding Ca^<2+> oscillation.2003
- Author(s)
  Tomida, T., Hirose, K., Takizawa, A., Shibasaki, F., Iino, M.
- Journal Title
  
  EMBO.J. 22
  
  Pages : 3825-3832
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic β-cells.2003
- Author(s)
  Eto, K., Yamashita, T., Hirose, K., Tsubamoto, Y., Ainscow, EK., Rutter, G.A., Kimura, S., Noda, M., Iino, M., Kadowaki, T.
- Journal Title
  
  Am.J Physiol.Endocrinol.Metab. 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Journal Article] Spatiotemporal Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptors Using Synthetic Small-Molecule Probes.2003
- Author(s)
  Inoue, T., Kikuchi, K., Hirose, K., Iino, M., Nagano, T.
- Journal Title
  
  Chem.Biol. 10
  
  Pages : 503-509
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390079
[Presentation] Alteration of the spatial DRD2 in the striatal subregion of schizophrenia model mice2017
- Author(s)
  大西泰地、並木繁行、廣瀬謙造
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎)
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 統合失調症モデルマウス腹側線条体におけるDRD2空間分布の変容2017
- Author(s)
  大西泰地、並木繁行、廣瀬謙造
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 統合失調症モデルマウス腹側線条体におけるDRD2空間分布の変容2017
- Author(s)
  大西泰地、並木繁行、廣瀬謙造
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K15048
[Presentation] Quantal nature of synaptic transmission visualized by a single synapse glutamate imaging technique2016
- Author(s)
  Kenzo Hirose
- Organizer
  Current Trends and Future Directions of Synaptic Plasticity Research
- Place of Presentation
  Baltimore(USA)
- Year and Date
  2016-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Regulation of synaptic vesicle exocytosis by nanoassembly of synaptic mokecules2016
- Author(s)
  Shigeyuki Namiki, Hirokazu Sakamoto, Tetsuro Ariyoshi, Kenzo Hirose
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川)
- Year and Date
  2016-07-22
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Subregion-specific alteration of DRD2 expression in the striatum of model mice of schizophrenia.2016
- Author(s)
  大西泰地、中山翔太、並木繁行、坂本寛和、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15048
[Presentation] Analysis of synaptic molecular arrangement in a mouse model of schizophrenia2016
- Author(s)
  中山翔太、並木繁行、坂本寛和、宮川剛、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Subregion-specific alteration of DRD2 expression in the striatum of model mice of schizophrenia2016
- Author(s)
  大西泰地、中山翔太、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Subregion-specific alteration of DRD2 expression in the striatum of model mice of schizophrenia2016
- Author(s)
  大西泰地、中山翔太、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Analysis of synaptic molecular arrangement in a mouse model of schizophrenia2016
- Author(s)
  中山翔太、並木繁行、坂本寛和、宮川剛、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Analysis of synaptic molecular arrangement in a mouse model of schizophrenia2016
- Author(s)
  中山翔太、並木繁行、坂本寛和、宮川剛、廣瀬謙造
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15048
[Presentation] Regulation of synaptic vesicle exocytosis by nanoassembly of synaptic molecules2016
- Author(s)
  Shigeyuki Namiki，Hirokazu Sakamoto，Tetsuro Ariyoshi，Kenzo Hirose
- Organizer
  日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2016-07-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K15048
[Presentation] シナプス前部における Munc13-1 ナノクラスタ形成の分子機構について2015
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプス前部における Munc13-1 ナノクラスタ形成の分子機構について2015
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] シナプス前部における Munc13-1 ナノクラスタ形成の分子機構について2015
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] The Imaging Technology to Investigate Synaptic Transmission2015
- Author(s)
  廣瀬　謙造
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ（埼玉県・さいたま市）
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Synaptic Function Illuminated by a Hybrid-Type Fluorescent Glutamate Probe2015
- Author(s)
  廣瀬　謙造
- Organizer
  New Biological Frontiers Illuminated by Molecular Sensors and Actuators
- Place of Presentation
  GIS Convention Center at National Taiwan University（Taipei, Taiwan）
- Year and Date
  2015-06-30
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Molecular mechanisms for the formation of Munc13-1 nanoclusters at presynaptic terminals2015
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場、神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Molecular mechanisms for the formation of Munc13-1 nanoclusters at presynaptic terminals2015
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Synaptic Function Illuminated by a Hybrid-Type Fluorescent Glutamate Probe2015
- Author(s)
  廣瀬　謙造
- Organizer
  New Biological Frontiers Illuminated by Molecular Sensors and Actuators
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2015-06-30
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] The Imaging Technology to Investigate Synaptic Transmission2015
- Author(s)
  廣瀬　謙造
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  埼玉県さいたま市
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 超解像顕微鏡によって視覚化されたシナプス前終末におけるカルシウムチャネルの空間配置2014
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 超解像顕微鏡法によるシナプス機能を担う分子構築の解明2014
- Author(s)
  廣瀬謙造
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプスにおけるグルタミン酸放出のイメージング2014
- Author(s)
  廣瀬謙造
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 新規酸性環境検出蛍光プローブによるエキソサイトーシスダイナミクス可視化手法2014
- Author(s)
  浅沼大祐、高岡洋輔、並木繁行、長野哲雄、浦野泰照、廣瀬謙造
- Organizer
  第9回日本ケミカルバイオロジー学会
- Place of Presentation
  大阪大学豊中キャンパス（大阪府豊中市）
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 超解像顕微鏡によって視覚化されたシナプス前終末におけるカルシウムチャネルの空間配置2014
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 細胞スクリーニングを介した自閉症関連遺伝子の探索2014
- Author(s)
  武井大祐、並木繁行、太向勇、浅沼大祐、伊佐真幸、菅生厚太郎、竹島美幸、岩山佳美、山田和男、吉川武男、竹島浩、廣瀬謙造
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2014-03-21
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプスにおけるグルタミン酸放出のイメージング2014
- Author(s)
  廣瀬謙造
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Year and Date
  2014-03-16
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプス伝達を可視化する蛍光性グルタミン酸センサーの開発2014
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2014-03-20
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 新規酸性環境検出蛍光プローブによるエキソサイトーシスダイナミクス可視化手法2014
- Author(s)
  浅沼大祐、高岡洋輔、並木繁行、長野哲雄、浦野泰照、廣瀬謙造
- Organizer
  第9回日本ケミカルバイオロジー学会
- Place of Presentation
  大阪大学豊中キャンパス（大阪府豊中市）
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 超解像顕微鏡によって視覚化されたシナプス前終末におけるカルシウムチャネルの空間配置2014
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 超解像顕微鏡法によるシナプス機能を担う分子構築の解明2014
- Author(s)
  廣瀬謙造
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 中枢神経系におけるグルタミン酸およびATPの蛍光イメージング2014
- Author(s)
  廣瀬謙造
- Organizer
  STROKE2014
- Place of Presentation
  大阪国際会議場
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] シナプス伝達を可視化する蛍光性グルタミン酸センサーの開発2014
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第87回　日本薬理学会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 中枢神経系におけるグルタミン酸およびATPの蛍光イメージング2014
- Author(s)
  廣瀬謙造
- Organizer
  STROKE2014
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-03-14
- Invited
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプス伝達を可視化する高性能グルタミン酸センサーの開発2013
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] グルタミン酸イメージング技術を用いた神経伝達物質放出の分子基盤の解析2013
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第36回　日本神経科学大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] Supramolecular assembly controls neurotransmitter release2013
- Author(s)
  廣瀬謙造
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] シナプス伝達を可視化する高性能グルタミン酸センサーの開発2013
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場・福岡県
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] シナプス伝達を可視化する高性能グルタミン酸センサーの開発2013
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] エキソサイトーシスダイナミクスを可視化する酸性環境検出蛍光プローブ2013
- Author(s)
  浅沼大祐、高岡洋輔、並木繁行、瀧川健司、神谷真子、長野哲雄、浦野泰照、廣瀬謙造
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 新規FRET型蛍光プローブによって明らかにされた神経細胞での入力パターンのCdc42活性へのカルシウム依存的な変換機構2013
- Author(s)
  太田裕作、岸俊輔、並木繁行、廣瀬謙造
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] ナノスコピーによる精神病態へのアプローチ2013
- Author(s)
  廣瀬謙造
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 細胞シグナル動態を可視化するハイブリッド型蛍光プローブ2013
- Author(s)
  廣瀬謙造
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-22
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Supramolecular assembly controls neurotransmitter release2013
- Author(s)
  廣瀬謙造
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2013-12-04
- Invited
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 新規FRET型蛍光プローブによって明らかにされた神経細胞でのカルシウムによるCdc42の活性調節機構の解明2013
- Author(s)
  太田裕作、岸俊輔、並木繁行、廣瀬謙造
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2013-06-22
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] グルタミン酸イメージング技術を用いた神経伝達物質放出の分子基盤の解析2013
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] ナノスコピーによる精神病態へのアプローチ2013
- Author(s)
  廣瀬謙造
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会　合同年会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2013-10-26
- Invited
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 酸性環境検出蛍光プローブによるエキソサイトーシスダイナミクスの可視化2013
- Author(s)
  浅沼大祐、高岡洋輔、並木繁行、長野哲雄、浦野泰照、廣瀬謙造
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋大学東山キャンパス（愛知県名古屋市）
- Year and Date
  2013-09-29
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] シナプス伝達を可視化する高性能グルタミン酸センサーの開発2013
- Author(s)
  瀧川健司、並木繁行、坂本寛和、有吉哲郎、金原直也、浅沼大祐、廣瀬謙造
- Organizer
  第8回日本分子イメージング学会総会・学術集会
- Place of Presentation
  横浜赤レンガ倉庫（神奈川県横浜市）
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Analyzing molecular basis of presynaptic function with fluorescent glutamate indicator2013
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第6回MCCS-Asiaシンポジウム
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2013-06-19
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] エキソサイトーシスダイナミクスを可視化する酸性環境検出蛍光プローブ2013
- Author(s)
  浅沼大祐、高岡洋輔、並木繁行、長野哲雄、浦野泰照、廣瀬謙造
- Organizer
  第8回日本分子イメージング学会総会・学術集会
- Place of Presentation
  横浜赤レンガ倉庫（神奈川県横浜市）
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 脳スライスにおける単一シナプス解像度でのグルタミン酸イメージング技術の開発2012
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬健造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 脳スライスにおける単一シナプス解像度でのグルタミン酸イメージング技術の開発2012
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬健造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] グルタミン酸イメージングによるプレシナプス機能を制御する分子基盤の解析2012
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] 蛍光グルタミン酸プローブを用いた神経伝達物資放出を制御する分子基盤の解析2012
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  北里大学薬学部・東京都
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 脳スライスにおける単一シナプス解像度でのグルタミン酸イメージング技術の開発2012
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場・愛知県
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 蛍光イメージングプローブのハイスループット作製技術の開発2012
- Author(s)
  瀧川健司、並木繁行、坂本寛和、浅沼大祐、廣瀬謙造
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府・山梨県
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] グルタミン酸イメージングによるプレシナプス機能を制御する分子基盤の解析2012
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場・愛知県
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 新規FRET型蛍光プローブによって明らかにされた神経細胞でのカルシウムによるCdc42の活性調節機構の解明2012
- Author(s)
  太田裕作、岸俊輔、並木繁行、廣瀬謙造
- Organizer
  第127回日本薬理学会関東部会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 蛍光イメージングプローブのハイスループット作製技術の開発2012
- Author(s)
  瀧川健司、並木繁行、坂本寛和、浅沼大祐、廣瀬謙造
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府
- Year and Date
  2012-09-03
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] 蛍光グルタミン酸プローブを用いた神経伝達物資放出を制御する分子基盤の解析2012
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  北里大学薬学部
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] グルタミン酸イメージングによるプレシナプス機能を制御する分子基盤の解析2012
- Author(s)
  金原直也、坂本寛和、太向勇、並木繁行、廣瀬謙造
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] ゲノムワイドRNAi構築技術の開発2009
- Author(s)
  太向勇, 菅尾光太郎, 廣瀬謙造
- Organizer
  日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19659052
[Presentation] 生細胞分子イメージングのためのハイブリッド型プローブ2008
- Author(s)
  廣瀬謙造
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19390063
[Presentation] 生細胞分子イメージングのためのハイブリッド型プローブ2008
- Author(s)
  廣瀬謙造
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19390063
[Presentation] 生細胞分子イメージングのためのハイブリッド型プローブ2008
- Author(s)
  廣瀬謙造
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-16083206
[Presentation] RNAi library for Potential Dug Target discovery2006
- Author(s)
  Kenzo Hirose.
- Organizer
  XVth World Congress of Pharmacology IUPHAR
- Place of Presentation
  北京
- Data Source
  KAKENHI-PROJECT-16083206
[Presentation] 細胞内カルシウムシグナリングの可視化2006
- Author(s)
  廣瀬謙造
- Organizer
  第79回日本薬理学会年会学術奨励賞受賞講演
- Place of Presentation
  横浜
- Year and Date
  2006-03-09
- Data Source
  KAKENHI-PROJECT-16083206
[Presentation] EPRILテクノロジーによるRNAiライブラリー2006
- Author(s)
  廣瀬謙造
- Organizer
  第79回日本薬理学会年会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2006-03-08
- Data Source
  KAKENHI-PROJECT-16083206
[Presentation] 小脳プルキンエ細胞におけるNOイメージング2005
- Author(s)
  廣瀬謙造
- Organizer
  日本顕微鏡学会第61回学術講演会
- Place of Presentation
  筑波
- Year and Date
  2005-06-01
- Data Source
  KAKENHI-PROJECT-16083206
[Presentation] Supramolecular assemblies of synaptic proteins for synaptic vesicle release site at central synapses
- Author(s)
  Shigeyuki Namiki, Hirokazu Sakamoto, Tetsuro Ariyoshi, Naoya Kimpara and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Supramolecular assemblies of synaptic proteins for synaptic vesicle release site at central synapses
- Author(s)
  Shigeyuki Namiki, Hirokazu Sakamoto, Tetsuro Ariyoshi, Naoya Kimpara and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] グルタミン酸イメージを用いたグルタミン酸放出の分子基盤の解析
- Author(s)
  金原直也、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  2013年度　包括脳ネットワーク夏のワークショップ
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 脳スライス標本内単一シナプスについての短期可塑性解析に向けたグルタミン酸イメージング技術の開発
- Author(s)
  有吉哲郎、坂本寛和、並木繁行、廣瀬謙造
- Organizer
  2013年度　包括脳ネットワーク夏のワークショップ
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] 超解像イメージングで見えたシナプス小胞開口放出が起こる場所
- Author(s)
  坂本寛和、並木繁行、廣瀬謙造
- Organizer
  2013年度　包括脳ネットワーク夏のワークショップ
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] Supramolecular organization underlying synaptic transmission.
- Author(s)
  廣瀬謙造
- Organizer
  Systems Biology of Cellular Signaling（International Symposium）
- Place of Presentation
  東京大学小柴ホール(東京)
- Invited
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Analyzing molecular basis of neurotransmitter release with fluorescent glutamate imaging
- Author(s)
  Naoya Kinpara, Hirokazu Sakamoto, Shigeyuki Namiki and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-24590313
[Presentation] Analyzing molecular basis of neurotransmitter release with fluorescent glutamate imaging
- Author(s)
  Naoya Kimpara, Hirokazu Sakamoto, Shigeyuki Namiki and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-ORGANIZER-24116001
[Presentation] Analyzing molecular basis of neurotransmitter release with fluorescent glutamate imaging
- Author(s)
  Naoya Kimpara, Hirokazu Sakamoto, Shigeyuki Namiki and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-PLANNED-24116004
[Presentation] Supramolecular assemblies of synaptic proteins for synaptic vesicle release site at central synapses
- Author(s)
  Shigeyuki Namiki, Hirokazu Sakamoto, Tetsuro Ariyoshi, Naoya Kinpara and Kenzo Hirose
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre（南アフリカ共和国ケープタウン）
- Year and Date
  2014-07-16 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-24590313

1. NAMIKI Shigeyuki (90452193)

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2. NAKAYAMA Shinsuke (30192230)

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29. HASHIMOTO Kenji (10189483)

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42. FUKASAKU Noboru

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55. MIYAMOTO Hiroyuki

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56. ARUGA Jun

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HIROSE Kenzo 廣瀬 謙造

Research Projects

Research Products

Co-Researchers

中枢カテコラミンの蛍光イメージング技術の開発Principal InvestigatorOngoing

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Principal Investigator

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Principal Investigator

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Transformation of the relationship between synaptic supramolecular assemblies and synaptic function in mental disorderPrincipal Investigator

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Review Section

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Principal Investigator

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Principal Investigator

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Visualization analysis of spatiotemporal dynamics of glutamate in central nervous systemPrincipal Investigator

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長期増強現象を担うPDZドメイン含有蛋白質の網羅的分子スクリーニング法の開発Principal Investigator

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大規模RNAiライブラリーを用いたカルシウム流入分子機構の網羅的探索Principal Investigator

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Integration of intracellular nanosystems in calcium signalingPrincipal Investigator

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味細胞内情報伝達のin situイメージング法による甘味感知の分子機構の解明Principal Investigator

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LTD and spatio-temporal dynamics of IP_3 within cerebellar Purkinje cellsPrincipal Investigator

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HIROSE Kenzo 廣瀬謙造