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Takeshima Hiroshi  竹島 浩

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TAKESHIMA Hiroshi  竹島 浩

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Researcher Number 70212024
External Links
Affiliation (Current) 2022: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 京都大学, 薬学研究科, 教授
2012 – 2015: 京都大学, 薬学研究科(研究院), 教授
2011: 京都大学, 大学院・薬学研究科, 教授
2006 – 2011: 京都大学, 薬学研究科, 教授
2007: 京都大学, 大学院・薬学研究科, 教授 … More
2006: 京都大学, 大学院薬学系研究科, 教授
2005: 京都大学, 大学院・薬学研究科, 教授
2005: 東北大学, 大学院・医学系研究科, 非常勤講師
2004: Tohoku University, Graduate School of Medicine, Professor, 薬学研究科, 教授
2004: 東北大学, 医学系研究科, 教授
2001 – 2004: 東北大学, 大学院・医学系研究科, 教授
2000 – 2001: Institute of Life Science, Kurume University, 分子生命科学研究所, 教授
1997 – 1999: 東京大学, 大学院・医学系研究科, 助教授
1995 – 1997: 東京大学, 医学部, 助教授
1994 – 1995: 埼玉医科大学, 医学部, 講師
1994: 埼玉医科大学, 薬理学教室, 講師
1989 – 1991: 京都大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Biological Sciences / General physiology / Basic Section 48020:Physiology-related / Environmental physiology (including Physical medicine and Nutritional physiology) / Biological pharmacy / Pathological medical chemistry / Neurophysiology and muscle physiology / Cell biology / Functional biochemistry … More / General physiology / 広領域 / General medical chemistry / General medical chemistry … More
Except Principal Investigator
Biological Sciences / Functional biochemistry / General pharmacology / Basic Section 48020:Physiology-related / Basic Section 53020:Cardiology-related / Basic Section 59020:Sports sciences-related Less
Keywords
Principal Investigator
小胞体 / リアノジン受容体 / ノックアウトマウス / TRICチャネル / ノシセプチン / ノシセプチン受容体 / ジャンクトフィリン / Ca2+放出 / ryanodine receptor / ミツグミン53 … More / 結合膜構造 / カウンターイオン / カルシウムストア / 筋収縮 / 記憶学習 / Ca2+シグナル / Ca2+結合タンパク質 / 小胞体Ca2+放出 / Ca2+ストア / カフェイン / muscle contraction / caffeine / Ca^<2+> release channel / オピオイドペプチド / オピオイド受容体 / 聴覚調節 / 長期増強 / 疼痛 / 神経ペプチド / カルシウムシグナリング / シグナルシークエンストラップ法 / RBCCファミリー / TRIMファミリー / 神経可塑性 / 後過分極 / ミツグミン23 / 細胞内カルシウムストア / カルミン / 筋小胞体 / TRIM50 / 細胞内カルシウム / リアノジン / カルシウム放出チャネル / intracellular Ca^<2+> / 三つ組構造 / Ca^<2+>放出チャネル / 興奮収縮連関 / junctophilin / イオンチャネル / モルヒネ / 鎖 ノシセプチン / G蛋白カップル受容体 / 疼痛反応 / オピオイド耐性 / オルファン受容体 / 神経細胞 / 受容体 / シグナル伝達 / 蛋白リン酸化 / 疼痛調節 / ノシスタチン / 疼痛伝達 / 鎮痛薬 / カリウムチャネル / 心筋細胞 / 骨格筋細胞 / 細胞膜 / エンドソーム / E3ユビキチンリガーゼ / 骨格筋 / 心筋 / 小胞体Ca^<2+>放出 / 膜修復 / 肺胞上皮細胞 / 筋ジストロフィー / 後科分極 / Ca2+チャネル / 容量依存性Ca2+流入 / 小胞体ストレス / 膜タンパク質 / 細胞内Ca^<2+>ストア / IP3受容体 / サルコペニア / 筋老化 / 筋萎縮 / Ca^<2+>ハンドリング / サルカルメニン / 小胞体Ca2+ポンプ / 加齢骨格筋 / 心不全 / Ca2+ハンドリング / 筋委縮 / 遺伝子発現 / 病態マーカー / microRNA / 血管平滑筋 / ミツグミン23 / Ca2+スパーク / 脂質二重膜再構成 / 単粒子解析 / 高血圧 / 小胞体Ca2+ / Ca2+取り込み / Ca2+ポンプ / MG53 / カルシウム放出チャンネル / calcium release channel / intracellular calcium / ryanodine / Ca^<2+> 放出チャネル / カルシウム・ストア / ジヒドロピリジン受容体 / Ca^<2+>シグナリング / Ca^2^+放出チャネル / Ca^2^+シグナリング / Excitation-contraction coupling / fihydropyridina receptor / Ca^<2+> sigualing / nociceptin / nociceptin receptor / opioids / opioid receptors / カルシウム放出 / Ca^<2+>ストア / Ca^<2+>チャネル / intracellular calcium ions / calcium release / junctional membrane / チャネル機能共役 / K+チャネル / Ca2+依存性K+チャネル / 興奮性細胞 / ジャンクロフィリン / Ca^<2+> release / endoplasmic reticulum / Calumin / TRIC channel / junctional membrane complex / channel crosstalk / ミツグミン56 / 生理学 / 骨芽細胞 / MG56 / Ca2+シグナリング / MG23チャネル … More
Except Principal Investigator
リアノジン受容体 / 筋小胞体 / カルシウム / 興奮収縮連関 / カルシウム放出チャネル / CaによるCa放出(CICR) / 骨格筋 / ノックアウトマウス / イオンチャネル / 遺伝子 / 小胞体 / カルシウム放出チャンネル / 筋収縮 / ジーンターゲッティング / カルシウムイオン / 分子生物学 / カルモジュリン / スキンド・ファイバー / 骨格筋型,脳型リアノジン受容体 / リアノジン受容体欠損マウス(dyspedic mouse) / 心筋 / 画像解析 / 蛍光カルシウム指示薬 / 心拍変動 / パワースペクトル / 最大エントロピー法 / 心筋細胞 / 心臓交感神経 / 心臓副交感神経 / 一酸化窒素 / リン酸化 / ミオシン / イノシトール三リン酸 / イメージング / プルキンエ細胞 / 血管 / リシ酸化 / NFAT / クラスリン / エンドサイトーシス / リン脂質 / rho GTPase / GAP / トランスフェリン受容体 / 輸送体 / プロスタグランジン / 傍糸球体装置 / 近位尿細管 / レニン / 膜輸送 / トランスポーター / 複合体 / 生体膜 / 上皮輸送 / 分子複合体 / ポンプ / 生体恒常性 / リアノジン受容体(1型) / リアノジン受容体(3型) / Ca^<2+>によるCa^<2+>放出(CICR) / カルモデュリン / リアノジン受容体(骨格筋型) / リアノジン受容体(脳型) / 筋拘縮 / calcium release channel / type 1 ryanodine receptor / type 3 ryanodine receptor / Ca-induced Ca release (CICR) / sarcoplasmic reticulum / skeletal muscle / excitation-contraction coupling (EC coupling) / calmodulin / 生理学 / バイオテクノロジー / 薬理学 / 細胞・組織 / 生体分子 / 上皮細胞 / Ca^<2+>シグナリング / Ca^<2+>チャネル / gene / physiology / biotechnologv / pharmaco logy / cell, tissue / ion channel / ニコチン性アセチルコリン受容体 / Na^+チャンネル / Ca^<2+>チャンネル / Ca^<2+>放出チャンネル / ムスカリン性アセチルコリン受容体 / cDNA発現 / 静位特異的変異 / 部位特異的変異 / グルタミン酸受容体 / Ca^<2+> releaseチャンネル / cGMP-gatedチャンネル / K^+チャンネル / 電位感受機構 / パッチクランプ法 / E-C coupling / ムスカリン性アセチルコリン受容体サブタイプ / Nicotinic acetylcholine receptor / Na^+ channel / Ca^<2+> channel / Ca^<2+> release channel / Muscarinic acetylcholine receptor / cDNA expression / Site-directed mutagenesis / Excitation-contraction coupling / イオン / マウス / 心室細動 / 突然死 / リアノジン / 特発性心室細動 / ミツグミン23 / スキンドファイバー / 骨格筋疲労 / 不活動 Less
  • Research Projects

    (40 results)
  • Research Products

    (137 results)
  • Co-Researchers

    (59 People)
  •  活動量の変化に伴う骨格筋の可塑的変化のメカニズムの解明

    • Principal Investigator
      渡邊 大輝
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  TRIC and MG23 channels in store Ca2+ handlingPrincipal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Kyoto University
  •  心調律における細胞内小胞体カウンターイオンチャネル(TRIC)の重要性

    • Principal Investigator
      村上 学
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Hirosaki University
  •  The genetic analysis and underlying function of the endoplasmic reticulum membrane protein targeting inherited arrhythmogenic syndromes

    • Principal Investigator
      伊藤 英樹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Hiroshima University
  •  Study on TRIC and MG23 channelsPrincipal Investigator

    • Principal Investigator
      Takeshima Hiroshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Kyoto University
  •  Study on TRIC channel and MG56Principal Investigator

    • Principal Investigator
      Takeshima Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Kyoto University
  •  Vesicular dynamics in parietal and muscle cellsPrincipal Investigator

    • Principal Investigator
      Takeshima Hiroshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Kyoto University
  •  Counter ion movement during Ca2+ releasePrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University
  •  Study of TRIC and MG23 channelsPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kyoto University
  •  Identification of muscular senescence-related genesPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University
  •  Roles of novel intracellular ion channelsPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Channel micro-assembly in junctional membrane complexesPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
      Tohoku University
  •  Transportsome on biomembrane systems: its molecular assembly and physiological function.

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2005 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
      Kyorin University
  •  新規小胞体膜タンパク質CSNの構造と機能Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General physiology
    • Research Institution
      Kyoto University
      Tohoku University
  •  中枢神経系におけるジャンクトフィリンの生理機能Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  ミツグミン53に関する研究Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  エンドフィリン複合体のクラスリンを介するエンドサイトーシスにおける機能の解析

    • Principal Investigator
      根本 康夫
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tohoku University
  •  A study on the molecular hasis of intracellular Ca^<2+> storesPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
      Tohoku University
  •  3型ジャンクトフィリンとハンチントン類似病Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  新規受容体蛋白ファミリーの機能解析Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      Kurume University
  •  ノシセプチン受容体欠損マウスにおける中枢機能の補充機序Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Tohoku University
  •  Structure and function of ryanodine receptorPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokoku University
      Kurume University
  •  細胞内シグナルフローの可視化解析

    • Principal Investigator
      飯野 正光
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Molecular physiological characterization of Ca2+ signal-regulating ion channels that control vectorial substance transport

    • Principal Investigator
      MORI Eyasuo
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University, Graduate School of Engineering
      Okazaki National Research Institutes
  •  Molecular contraction of Ca^<2+> signalingPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General pharmacology
    • Research Institution
      Institute of Life Science, Kurume University
      The University of Tokyo
  •  Nociceptin receptor antagonistPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      広領域
    • Research Institution
      Institute of Life Science, Kurume University
      The University of Tokyo
  •  ノシセプチン受容体による記憶学習および長期増強の調節Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  記憶学習とオピオイド耐性における可塑性へのノシセプチン系の関与Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  新規神経ペプチドの検索と単離Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokyo
  •  リマノジンタイプ3受容体欠損マウスの体温および自律神経調節機能の研究

    • Principal Investigator
      桑木 共之
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Structure and function of ryanodine receptorsPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokyo
  •  興奮収縮連関機構の構造機能協関

    • Principal Investigator
      飯野 正光
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  オピオイド受容体相同物(ROR-C,MOR-C)の中枢神経系における機能Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokyo
  •  Functional analysis of ryanodine receptor using molecular genetic techniquePrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tokyo
  •  骨格筋小胞体カルシウム放出チャネルとカルシウムポンプの機能協関

    • Principal Investigator
      ENDO Makoto
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Saitama Medical University
  •  オピオイド受容体分子のジーンターゲッティングによる生理機能解析Principal Investigator

    • Principal Investigator
      竹島 浩
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Saitama Medical University
  •  Functions of the two types of calcium release channels in the sarcoplasmic reticulum of skeletal muscle.

    • Principal Investigator
      ENDO Makoto
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Saitama Medical School
  •  リアノジン受容体/カルシウム放出チャンネル遺伝子欠失マウスの作製と解析

    • Principal Investigator
      竹島 美幸
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Institute of Psychiatry
  •  Molecular biological studies of ryanodine receptor/calcium release channelPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hiroshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Saitama Medical School
  •  Studies on the structure and function of neurotransmitter receptors and ionic channels

    • Principal Investigator
      NUMA Shosaku
    • Project Period (FY)
      1988 – 1991
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kyoto University

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All Journal Article Presentation Book

  • [Book] リアノジン受容体を介するチャネル共役による神経機能,脳21(vol. 16)2013

    • Author(s)
      竹島浩
    • Data Source
      KAKENHI-PROJECT-24657133
  • [Book] TRIC チャネルと高血圧2013

    • Author(s)
      山崎大樹、陶晟辰、竹島浩
    • Publisher
      Clinical Calcium
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Book] トランスポートソームの世界2011

    • Author(s)
      金井好克、竹島浩、森泰生、久保義弘編集
    • Total Pages
      471
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Book] トランスポートソームの世界2010

    • Author(s)
      金井好克、竹島浩、森泰生、久保義弘
    • Total Pages
      471
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Book] Junctophilin. Encyclopedia of movement disorders.2009

    • Author(s)
      Takeshima, H.
    • Publisher
      Elsevier Limitted
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Book] 医歯薬系学生のための基礎生命科学2008

    • Author(s)
      竹島浩、山崎哲男、池田篤史、輿水崇鏡
    • Total Pages
      214
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Book] イオンチャネル最前線(リアノジン受容体, 医学のあゆみ別冊)2005

    • Author(s)
      竹島浩
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Book] イオンチャネル最前線(医学のあゆみ別冊)2005

    • Author(s)
      竹島 浩
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-15109005
  • [Book] イオンチャネル最前線(医学のあゆみ別冊)2005

    • Author(s)
      竹島 浩
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Book] イオンチャネル最前線(医学のあゆみ別冊),pp.171-175担当2005

    • Author(s)
      竹島 浩
    • Total Pages
      273
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-17659060
  • [Book] イオンチャネル最前線(医学のあゆみ別冊),pp.171-175担当2005

    • Author(s)
      竹島 浩
    • Total Pages
      273
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Book] Ryanodine receptors 14 (Knockout mice lacking rqanoclire receptor and junctophiline subtypes.)(ed.Wehrens XHT, Marks AR)2004

    • Author(s)
      Takeshima H.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] nhanced Ca2+ handling in thioglycolate-elicited peritoneal macrophages.2021

    • Author(s)
      Liu Feng、Xu Luxin、Nishi Miyuki、Ichimura Atsuhiko、Takeshima Hiroshi
    • Journal Title

      Cell Calcium

      Volume: 96 Pages: 102381-102381

    • DOI

      10.1016/j.ceca.2021.102381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K11306, KAKENHI-PROJECT-18H02597
  • [Journal Article] TRIC-A channel maintains store calcium handling by interacting with type 2 ryanodine receptor in cardiac muscle.2020

    • Author(s)
      Zhou X, Park KH, Yamazaki D, Lin PH, Nishi M, Ma Z, Qiu L, Murayama T, Zou X, Takeshima H, Zhou J, Ma J.
    • Journal Title

      Circ. Res.

      Volume: 126 Pages: 417-435

    • DOI

      10.1161/circresaha.119.316241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07313, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-17K01845, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-18H02597
  • [Journal Article] Decreased cardiac pacemaking and attenuated b-adrenergic response in TRIC-A knockout mice.2020

    • Author(s)
      Murakami, M., Toyama, Y., Yonekura, M., Ohba, T., Matsuzaki, Y., Sawamura, D., Murakami, A. M., Nishi, M., Itagaki, S., Tomita, H. & Takeshima, H. 15, 2020. Doi:
    • Journal Title

      PLOS One

      Volume: 15

    • DOI

      10.1371/journal.pone.0230465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02597
  • [Journal Article] Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice2020

    • Author(s)
      Murakami M, Toyama Y, Yonekura M, Ohba T, Matsuzaki Y, Sawamura D, Murakami AM, Nishi M, Itagaki S, Tomita H, Takeshima H.
    • Journal Title

      PLOS ONE

      Volume: 15 Pages: 1-12

    • DOI

      10.1371/journal.pone.0244254

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07255, KAKENHI-PROJECT-20K08665, KAKENHI-PROJECT-20K11306, KAKENHI-PROJECT-17H04319, KAKENHI-PROJECT-18K08286
  • [Journal Article] 遺伝性不整脈疾患における筋小胞体Caシグナリング2020

    • Author(s)
      伊藤英樹、堀江 稔、竹島 浩
    • Journal Title

      Bio Clinica

      Volume: 35 Pages: 76-79

    • Data Source
      KAKENHI-PROJECT-20K08473
  • [Journal Article] Cooperative gating between TRIC-B channels; an ER/SR mechanism to enhance counterion currents.2019

    • Author(s)
      O'Brien F, Eberhardt D, Witschas K, El-Ajouz S, Iida T, Nishi M, Takeshima H, Sitsapesan R, Venturi E.
    • Journal Title

      J. Physiol.

      Volume: 印刷中 Pages: 2691-2705

    • DOI

      10.1113/jp277241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01845, KAKENHI-PROJECT-18H02597
  • [Journal Article] TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development2019

    • Author(s)
      Qian N, Ichimura A, Takei D, Sakaguchi R, Kitani A, Nagaoka R, Tomizawa M, Miyazaki Y, Miyachi H, Numata T, Kakizawa S, Nishi M, Mori Y, Takeshima H.
    • Journal Title

      Sci Signal.

      Volume: 12 Pages: 4847-4847

    • DOI

      10.1126/scisignal.aaw4847

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01845, KAKENHI-PROJECT-18H02597, KAKENHI-PROJECT-15K06774, KAKENHI-PROJECT-18K11044, KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-19K06955, KAKENHI-PROJECT-19K22834, KAKENHI-PUBLICLY-18H04695, KAKENHI-PROJECT-16K05843, KAKENHI-PLANNED-26111004, KAKENHI-PROJECT-17H06228
  • [Journal Article] Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC-A.2017

    • Author(s)
      El-Ajouz S, Venturi E, Witschas K, Beech M, Wilson AD, Lindsay C, Eberhardt D, O'Brien F, Iida T, Nishi M, Takeshima H, Sitsapesan R.
    • Journal Title

      J. Physiol.

      Volume: 595 Pages: 4769-4784

    • DOI

      10.1113/jp273550

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01845, KAKENHI-PROJECT-15H04676
  • [Journal Article] <i><b>Gm7325</b></i><b> is MyoD-dependently expressed in activated muscle satellite </b><b>cells </b>2017

    • Author(s)
      Takei D, Nishi M, Fukada S, Doi M, Okamura H, Uezumi A, Zhang L, Yoshida M, Miyazato M, Ichimura A, Takeshima H.
    • Journal Title

      Biomedical Research

      Volume: 38 Issue: 3 Pages: 215-219

    • DOI

      10.2220/biomedres.38.215

    • NAID

      130006865614

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01845, KAKENHI-PLANNED-15H05933, KAKENHI-PROJECT-15H01843, KAKENHI-PROJECT-17H01524, KAKENHI-PROJECT-15H04676, KAKENHI-PROJECT-15H05652
  • [Journal Article] Mice lacking the intracellular cation channel TRIC-B have compromised collagen production and impaired bone mineralization2016

    • Author(s)
      C.Zhao, A.Ichimura, N.Qian, T.Iida, D.Yamazaki, N.Noma, M.Asagiri, K.Yamamoto, S.Komazaki, C.Sato, F.Aoyama, A.Sawaguchi, S.Kakizawa, M.Nishi, and H.Takeshima.
    • Journal Title

      Science Signaling

      Volume: 9

    • DOI

      10.1126/scisignal.aad9055

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01562, KAKENHI-PROJECT-15H04676, KAKENHI-PROJECT-15H04698, KAKENHI-PROJECT-15H05652, KAKENHI-PROJECT-14J06672, KAKENHI-PROJECT-15K06774, KAKENHI-PROJECT-15K14499
  • [Journal Article] Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.2016

    • Author(s)
      Pigoni, M., Johanna Wanngren, J., Kuhn, J-H., Munro, K. M., Jenny M. Gunnersen, J. M., Takeshima, H., Feederle, R., Voytyuk, I., Strooper, B. D., Levasseur, M. D., Hrupka, B. J., Stephan, A., M&uuml;ller, S. A. & Lichtenthaler, S. F.
    • Journal Title

      Mol. Neurodegener.

      Volume: 11 Pages: 67-67

    • DOI

      10.1186/s13024-016-0134-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04676
  • [Journal Article] Positive regulation of the enzymatic activity of gastric H(+),K(+)-ATPase by sialylation of its β-subunit.2016

    • Author(s)
      Fujii T, Watanabe M, Shimizu T, Takeshima H, Kushiro K, Takai M, Sakai H.
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Biomembranes

      Volume: 1858 Pages: 1228-1235

    • DOI

      10.1016/j.bbamem.2016.02.029

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460291, KAKENHI-PROJECT-15K15029, KAKENHI-PROJECT-25460282, KAKENHI-PROJECT-26870166, KAKENHI-PROJECT-25293047, KAKENHI-PROJECT-15H04676, KAKENHI-PROJECT-16K08490
  • [Journal Article] TRIM72 modulates Caveolar endocytosis in repair of lung cells.2015

    • Author(s)
      Nagre, N., Wang, S., Kellett, T., Kanagasabai, R., Deng, J., Nishi, M., Shilo, K., Oeckler, R., Yalowich, J., Takeshima, H., Christman, J., Hubmayr, R. & Zhao, Z.
    • Journal Title

      Am. J. Physiol. Lung Cell. Mol. Physiol.

      Volume: 310

    • DOI

      10.1152/ajplung.00089.2015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26650034
  • [Journal Article] Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation2015

    • Author(s)
      Van B, Nishi M, Komazaki S, Ichimura A, Kakizawa S, Nakanaga K, Aoki J, Park KH, Ma J, Ueyama T, Ogata T, Maruyama N, Takeshima H.
    • Journal Title

      FEBS Letter

      Volume: in press Pages: 1095-1104

    • DOI

      10.1016/j.febslet.2015.03.028

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24500470, KAKENHI-PROJECT-15K06774, KAKENHI-PROJECT-15H04676, KAKENHI-PROJECT-15H05652
  • [Journal Article] Ca2+ microdomains organized by junctophilins2015

    • Author(s)
      Takeshima, H., Hoshijima, M. & Song, L-S.
    • Journal Title

      Cell Calcium

      Volume: 58 Pages: 349-356

    • DOI

      10.1016/j.ceca.2015.01.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04676
  • [Journal Article] Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis2014

    • Author(s)
      Zhou, X., Lin, P., Yamazaki, D., Park, K-H., Komazaki, S., Chen, R. S. W., Takeshima, H. & Ma, J. .
    • Journal Title

      Circ. Res.

      Volume: 114 Pages: 706-716

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26650034
  • [Journal Article] Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis2014

    • Author(s)
      Zhou, X., Lin, P., Yamazaki, D., Park, K-H., Komazaki, S., Chen, R. S. W., Takeshima, H. & Ma, J.
    • Journal Title

      Circ. Res

      Volume: 114 Pages: 706-716

    • Data Source
      KAKENHI-PROJECT-24657133
  • [Journal Article] Facilitated hyperpolarization signaling in vascular smooth muscle-overexpressing TRIC-A channels2013

    • Author(s)
      Tao, S., Yamazaki, D., Komazaki, S., Zhao, C., Iida, T., Kakizawa, S., Imaizumi, Y. & Takeshima, H.
    • Journal Title

      J Biol Chem

      Volume: 288 Pages: 15581-15589

    • DOI

      10.1074/jbc.m112.435396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240055, KAKENHI-PROJECT-23390020, KAKENHI-PROJECT-23659037, KAKENHI-PUBLICLY-24111528, KAKENHI-PROJECT-24659131, KAKENHI-PROJECT-24680041, KAKENHI-PUBLICLY-25136717
  • [Journal Article] TRIC channels supporting efficient Ca^<2+> release from intracellular stores2013

    • Author(s)
      Venturi, E., Sitsapesan, R., Yamazaki, D. & Takeshima, H
    • Journal Title

      Pflugers Arch

      Volume: 465 Pages: 187-195

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] Enhanced dihydropyridine receptor calcium channel activity improves skeletal muscle strength2013

    • Author(s)
      Mosca, B., Bergamelli, L., Vukcevic, M, Lopez, R., Treves, S., Nishi, M., Takeshima, H., Paolini, C., Martini, M., Rispoli, G., Protasi, F. & Zorzato, F.
    • Journal Title

      Nat. Commun

      Volume: 4 Pages: 1541-1541

    • Data Source
      KAKENHI-PROJECT-24657133
  • [Journal Article] Enhanced dihydropyridine receptor calcium channel activity improves skeletal muscle strength2013

    • Author(s)
      Mosca, B., Bergamelli, L., Vukcevic, M, Lopez, R., Treves, S., Nishi, M., Takeshima, H., Paolini, C., Martini, M., Rispoli, G., Protasi, F. & Zorzato, F
    • Journal Title

      Nat. Commun

      Volume: 4 Pages: 1541-1541

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] TRIC-B channels display labile gating : evidence from the TRIC-A knockout mouse model2013

    • Author(s)
      Venturi, E., Matyjaszkiewicz, A., Pitt, S. J., Tsaneva-Atanasova, K., Nishi, M., Yamazaki, D., Takeshima, H. & Sitsapesan, R.
    • Journal Title

      Pflugers Arch - Eur J Physiol.

      Volume: 465 Pages: 1135-1148

    • DOI

      10.1007/s00424-013-1251-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240055, KAKENHI-PROJECT-24500470, KAKENHI-PROJECT-24659131
  • [Journal Article] Facilitated hyperpolarization signaling in vascular smooth muscle overexpressing TRIC-A channels2013

    • Author(s)
      Tao, S., Yamazaki, D., Komazaki, S., Zhao, C., Iida, T., Kakizawa, S., Imaizumi, Y. & Takeshima, H
    • Journal Title

      J. Biol. Chem

      Volume: 288 Pages: 15581-15589

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] TRIC-B channels display labile gating : evidence from the TRIC-A knockout mouse model2013

    • Author(s)
      Venturi, E., Matyjaszkiewicz, A., Pitt, S J., Tsaneva-Atanasova, K., Nishi, M., Yamazaki, D., Takeshima, H. & Sitsapesan, R
    • Journal Title

      Pflugers Arch

      Volume: 465 Pages: 1135-1148

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] Sarcalumenin plays a critical role in age-related cardiac dysfunction due to decreases in SERCA2a expression and activity2012

    • Author(s)
      Jiao Q, et al.
    • Journal Title

      Cell Calcium

      Volume: 51 Pages: 31-39

    • DOI

      10.1016/j.ceca.2011.10.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-22659066, KAKENHI-PROJECT-24390200, KAKENHI-PUBLICLY-23136516
  • [Journal Article] TRIM50 regulates ventricular trafficking for acid secretion in gastric parietal cells.2012

    • Author(s)
      Nishi, M., Aoyama, F., Kisa, F., Zhu, H., Sun, M., Lin, P., Ohta, H., Yamamoto, S., Kakizawa, S., Sakai, H., Ma, J., Sawaguchi, A. & Takeshima, H.
    • Journal Title

      The J ournal of Biological Chemistry

      Volume: 287 Pages: 37523-33531

    • DOI

      10.1074/jbc.m112.370551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240055, KAKENHI-PROJECT-24500470, KAKENHI-PROJECT-24659095, KAKENHI-PROJECT-24790073
  • [Journal Article] Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy.2012

    • Author(s)
      Weisleder N, Takizawa N, Lin P, Wang X, Cao C, Zhang Y, Tan T, Ferrante C, Zhu H, Chen P-J, Yan R, Sterling M, Zhao X, Hwang M, Cai C, Cheng H, Takeshima H, Xiao R. & Ma J.
    • Journal Title

      Sc. Transl. Med.

      Volume: 4 Pages: 1-10

    • DOI

      10.1126/scitranslmed.3003921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240055, KAKENHI-PROJECT-24500470
  • [Journal Article] Sarcalumenin plays a critical role in age-related cardiac dysfunction due to decreases in SERCA2a expression and activity2012

    • Author(s)
      Jiao, Q., Takeshima, H., Ishikawa, Y. & Minamisawa, S
    • Journal Title

      Cell Calcium

      Volume: 51 Pages: 31-39

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] Endogenously determined restriction of food intake overcomes excitation-contraction uncoupling in JP45KO mice with aging.2012

    • Author(s)
      Delbono, O., Messi M. L., Wang, Z., Treves, S., Mosca, B., Bergamelli, L., Nishi, M., Takeshima, H., Shi H., Xue B. & Zorzato, F
    • Journal Title

      Exp.Gerontol

      Volume: 4 Pages: 304-316

    • DOI

      10.1016/j.exger.2012.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500382, KAKENHI-PROJECT-22659066, KAKENHI-PROJECT-24500470
  • [Journal Article] TRIM50 regulates vesicular trafficking for acid secretion in gastric parietal cells2012

    • Author(s)
      Nishi, M., Aoyama, F., Kisa, F., Zhu, H., Sun, M., Lin, P., Ohta, H., Yamamoto, S., Kakizawa, S., Sakai, H., Ma, J., Sawaguchi, A. & Takeshima, H
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 33523-33532

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] Mitsugumin 23 forms massive bowl-shaped assembly and cation-selective channel2011

    • Author(s)
      Venturi, E., Mio, K., Nishi, M., Ogura, T., Moriya, T., Okuda, K., Kakizawa, S., Sitapeasan, R., Chikara Sato, C. & Takeshima, H
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 2623-2632

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] TRIC-A Channels in Vascular Smooth Muscle Contribute to Blood Pressure Maintenance2011

    • Author(s)
      Yamazaki D, Tabara Y, Kita S, Hanada H, Komazaki S, Naitou D, Mishima A, Nishi M, Yamamura H, Yamamoto S, Kakizawa S, Miyachi H, Yamamoto S, Miyata T, Kawano Y, Kamide K, Ogihara T, Hata A, Umemura S, Soma M, Takahashi N, Imaizumi Y, Miki T, Iwamoto T, Ta
    • Journal Title

      Cell Metabolism

      Volume: 14 Pages: 231-241

    • DOI

      10.1016/j.cmet.2011.05.011

    • NAID

      120003255678

    • URL

      http://hdl.handle.net/2433/143634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185, KAKENHI-PROJECT-21500382, KAKENHI-PROJECT-22590254, KAKENHI-PROJECT-22790209, KAKENHI-PROJECT-22790288, KAKENHI-PUBLICLY-23136506, KAKENHI-PUBLICLY-23136512, KAKENHI-PROJECT-23240055, KAKENHI-PROJECT-23390020, KAKENHI-PROJECT-23590319, KAKENHI-PROJECT-23659037, KAKENHI-PROJECT-23790092
  • [Journal Article] TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance2011

    • Author(s)
      Yamazaki, D., Tabara, Y., Kita, S., Hanada, H., Komazaki, S., Naitou, D., Mishima, A., Nishi, M., Yamamura, H., Yamamoto, S., Kakizawa, S., Miyachi, H., Yamamoto, S., Miyata, T., Kawano, Y., Kamide, K., Ogihara, T., Hata, A., Umemura, S., Soma, M., Takahashi, N., Imaizumi, Y., Miki, T., Iwamoto, T. & Takeshima, H
    • Journal Title

      Cell Metab

      Volume: 14 Pages: 231-241

    • NAID

      120003255678

    • Data Source
      KAKENHI-PROJECT-23240055
  • [Journal Article] Facilitation of DNA damage-induced apoptosis by endoplasmic reticulum protein mitsugumin23.2010

    • Author(s)
      Yamazaki, T., Sasaki, N., Nishi, M., Takeshima, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 396

      Pages: 196-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Charade of the SR K^+-channel : two ion-channels, TRIC-A and TRIC-B, masquerade as a single K^+-channel.2010

    • Author(s)
      Pitt SJ, Park K-H, Nishi M, Urashima T, Aoki S, Yamazaki D, Ma J, Takeshima H., Sitsapesan R.
    • Journal Title

      Biophys.J.

      Volume: 99 Pages: 417-426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Charade of the SR K^<+->channel : two ion-channels, TRIC-A and TRIC-B, masquerade as a single K^<+->channel.2010

    • Author(s)
      Pitt S J, Park K-H, Nishi M, Takeshima H, et al.
    • Journal Title

      Biophys.J.

      Volume: 99 Pages: 417-426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Imparied Orail-mediateded resting Ca^<2+> entry reduces the cytosolic [Ca^<2+>] and SR Ca^<2+> loading in quitescent junctophilinl knockout myotubes.2010

    • Author(s)
      Li, H., Ding, X., Lopez, J.R., Takeshima, H., Ma, J., Allen, P.D., Eltit, J.M.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 39171-39179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Impaired Orail-mediated resting Ca^<2+> entry reduces the cytosolic [Ca^<2+>] and SR Ca^<2+> loading in quitescent junctophilin1 knockout myotubes.2010

    • Author(s)
      Li H, Ding X, Lopez JR, Takeshima H, Ma J, Allen PD, Eltit JM.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 39171-39179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659066
  • [Journal Article] Ca^<2+> overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle.2010

    • Author(s)
      Zhao X, Yamazaki D, Park K-H, Komazaki S, Tjondrokoesoemo A, Nishi M, Hirata Y, Brotto M, Takeshima H., Ma, J.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 37370-37376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] MG53 constitutes a primary determinant of cardiac ischemic preconditioning.2010

    • Author(s)
      Cao, C-M., Zhang, Y., Weisleder, N., Ferrante, C., Wang, X., Lv, F., Zhang, Y., Song, R., Hwang, M., Jin, L., Guo, J., Peng, W., Li, G., Nishi, M., Takeshima, H., Ma, J., Xiao, R-P.
    • Journal Title

      Circulation 121

      Pages: 2565-2574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Facilitation of DNA damage- induced apoptosis by endoplasmic reticulum protein mitsugumin23.2010

    • Author(s)
      Yamazaki, T., Sasaki, N., Nishi, M., Takeshima, H.
    • Journal Title

      Biochem.Biophys.Res. Commun. 392

      Pages: 196-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Molecular characterization of flubendiamide sensitivity in Iepidopterous ryanodine receptor.2010

    • Author(s)
      Kato, K., Kiyonaka, S., Sawaguchi, Y., Tohnish, M., Masaki, T., Yasokawa, N., Mizuno, Y., Mori, E., Inoue, K., Hamachi, I., Takeshima, H., Mori, Y.
    • Journal Title

      Biochemistry 48

      Pages: 10342-10352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Imparied Orail-mediateded resting Ca^<2+> entry reduces the cytosolic [Ca^<2+>] and SR Ca^<2+> loading in quitescent junctophilin1 knockout myotubes.2010

    • Author(s)
      Li H, Ding X, Lopez J R, Takeshima H, Ma J, Allen P D, Eltit J M.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 39171-39179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Ca^<2+> overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle.2010

    • Author(s)
      Zhao, X., Yamazaki, D., Park, K-H., Komazaki, S., Tjondrokoesoemo, A., Nishi, M., Lin, P., Hirata, Y., Brotto, M., Takeshima, H., Ma, J.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 37370-37376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Charade of the SR K^+-channel : two ion-channels, TRIC-A and TRIC-B, masquerade as a single K^+-channel.2010

    • Author(s)
      Pitt, S.J., Park, K-H., Nishi, M., Urashima, T., Aoki, S., Yamazaki, D., Ma, J., Takeshima, H., Sitsapesan, R.
    • Journal Title

      Biophys.J. 99

      Pages: 417-426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Imparied Orai1-mediateded resting Ca2+ entry reduces the cytosolic[Ca2+] and SR Ca2+ loading in quitescent junctophilin1 knockout myotubes2010

    • Author(s)
      Li, H., Ding, X., Lopez, J. R., Takeshima, H., Ma, J., Allen, P. D. & Eltit, J. M.
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 39171-39179

    • DOI

      10.1074/jbc.m110.149690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659066
  • [Journal Article] Mitsugumin 23 forms massive bowl-shaped assembly and cation-selective channel.2010

    • Author(s)
      Venturi E, Mio K, Nishi M, Ogura T, Moriya T, Okuda K, Kakizawa S, Sitapeasan R, Sato C., Takeshima H
    • Journal Title

      Biochemistry

      Volume: 50(印刷中) Pages: 2623-2632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Mitsugumin 53-mediated maintenance of K+ currents in cardiac myocytes.2009

    • Author(s)
      Masumiya.H., Asaumi. Y., Nishi, M., Minamisawa.S., Adachi. Akahane. S., Yoshida, M., Kangawa, K., Ito, K., Kagaya, Y., Yanagisawa, T., Yamazaki, T., Ma, J., Takeshima, H.
    • Journal Title

      Channels 3

      Pages: 6-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolon-3 and2009

    • Author(s)
      Cai, C., Weisleder.N., Ko, J.K., Komazaki, S.,Sunada. Y.,Nishi.M., Takeshima, H, Ma.J.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 15894-15902

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] MG53 nucleates assembly of cell membrane repair machinery2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Matsuda, N., Nishi, Hwang, M., Ko, J-K., Lin, P., Thornton, A., Zhao, X. , Pan, Z., Komazaki, S., Brotto, M., Takeshima, H. & Ma, J.
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Essential role of TRIC-B channel in Ca^<2+>- handling of alveolar epithelium and perinatal lung maturation.2009

    • Author(s)
      Yamazaki, D., Komazaki, S., Nakanishi, H., Mishima, A., Nishi, M., Yazawa, M., Yamazaki, T., Taguchi, R., Takeshima, H.
    • Journal Title

      Development 136

      Pages: 2355-2361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] MG53 regulates membrane budding and exocytosis in muscle cells2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Pan, Z., Nishi, M., Ko, J-K., Komazaki, S., Takeshima, H. & and Ma, J.
    • Journal Title

      J. Biol. Chem 284

      Pages: 3314-3322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Essential role of TRIC-B channel in Ca2+ handling of alveolar epithelium and perinatal lung maturation.2009

    • Author(s)
      Yamazaki, D., Komazaki, S., Nakanishi, H., Mishima, A., Nishi, M., Yazawa, M., Yamazaki, T., Taguchi, R., Takeshima, H.
    • Journal Title

      Development 136

      Pages: 2355-2361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Matsuda, N., Nishi, M., Hwang, M., Ko, J-K., Lin, P., Thornton, A., Zhao, X., Pan, Z., Komazaki, S., Brotto, M., Takeshima, H.^*, Ma, J.^* (*^co-corresponding authors)
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] (co-corresponding authors) MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, Hwang M, Ko J-K, Lin P, Thornton A, Zhao X, Pan Z, Komazaki S, Brotto M, Takeshima H, Ma J.
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Mitsugumin 53-mediated maintenance of K^+ currents in cardiac myocytes.2009

    • Author(s)
      Masumiya, H., Asaumi, Y., Nishi, M., Minamisawa, S., Adachi-Akahane, S., Yoshida, M., Kangawa, K., Ito, K., Kagaya, Y., Yanagisawa, T., Yamazaki, T., Ma, J., Takeshima, H.
    • Journal Title

      Channels 3

      Pages: 6-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] MG53 regulates membrane budding and exocytosis in muscle cells.2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Pan, Z., Nishi, M., Ko, J-K., Komazaki, S., Takeshima, H.^*, Ma, J.^* (*^co-corresponding authors)
    • Journal Title

      J.Biol.Chem. 284

      Pages: 3314-3322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] (*co-corresponding authors) MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Matsuda, N., Nishi, M., Hwang, M., Ko, J-K., Lin, P., Thornton, A., Zhao, X., Pan, Z., Komazaki, S., Brotto, M., Takeshima, H.*, Ma, J.*
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Essential role of TRIC-B channel in Ca^<2+>-handling of alveolar epithelium and perinatal lung maturation.2009

    • Author(s)
      Yamazaki, D., Komazaki, S., Nakanishi, H., Mishima, A., Nishi, M., Yazawa, M., Yamazaki, T., Taguchi, R., Takeshima, H.
    • Journal Title

      Development 136

      Pages: 2355-2361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai, C., Masumiya, H., Weisleder, N., Matsuda, N., Nishi, M., Hwang, M., Ko, J-K., Lin, P., Thornton, A., Zhao, X., Pan, Z., Komazaki, S., Brotto, M., Takeshima, H., Ma, J
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells2009

    • Author(s)
      Li XQ, Zheng YM, Rathore R, Ma J. Takeshima H., et.al.
    • Journal Title

      Pflugers Arch 457

      Pages: 771-783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Sarcalumenin is essential for maintaining cardiac function during endurance exercise training.2009

    • Author(s)
      Jiao,Q., Bai, Y., Akaike, T., Takeshima,H., Ishikawa, Y., et al.
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells2009

    • Author(s)
      Li, X. Q., Zheng, Y. M., Rathore, R., Ha, J., Takeshima, H. & Wang, Y. X
    • Journal Title

      Pflugers Arch. 457

      Pages: 771-783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] New molecular components supporting ryanodine receptor-mediated Ca2+ release : roles of junctophilin and TRIC2008

    • Author(s)
      Yamazaki, T., Yamazaki, D., Takeshima, H.
    • Journal Title

      Pharmacol. Ther. 121

      Pages: 265-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.2008

    • Author(s)
      Y amamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y.
    • Journal Title

      Nature Med. 14

      Pages: 738-747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice2008

    • Author(s)
      Sasaki A, Takasaki I, Andoh T, Shiraki K, Takeshima H, et.al.
    • Journal Title

      Neuroreport 19

      Pages: 83-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Sarcalumenin alleviates stress-induced cardiac dysfunction by improving Ca^<2+> handling of the sarcoplasmic reticulum.2008

    • Author(s)
      Shimura, M., Minamisawa, S., Takeshima, H., Jiao, Q., Bai, Y., Umemura, S., Ishikawa, Y.
    • Journal Title

      Cardiovasc. Res. 77

      Pages: 362-370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP.2008

    • Author(s)
      Stewart, R., Song, L., Carter, S.M., Sigalas, C., Zaccai, N.R., Kanamarlapudi, V., Bhat, M.B., Takeshima, H., Sitsapesan, R.
    • Journal Title

      J. Membr. Biol. 222

      Pages: 65-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] TRPM2-mediated Ca^<2+> influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.2008

    • Author(s)
      Yamamoto, S., Shimizu, S., Kiyonaka, S., Takahashi, N., Wajima, T., Hara, Y., Negoro, T., Hiroi, T., Kiuchi, Y., Okada, T., Kaneko, S., Lange, I., Fleig, A., Penner, R., Nishi, M., Takeshima, H, Mori, Y.
    • Journal Title

      Nature Med. 14

      Pages: 738-747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP.2008

    • Author(s)
      Stewart, R., Song, L., Carter, S.M., Sigalas, C., Zaccai, N.R., Kanamarlapudi, V., Bhat, M.B., Takeshima, H., Sitsapesan, R.
    • Journal Title

      J.Membr.Biol. 222

      Pages: 65-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Functional crosstalk between cell-surface and intracellular channels mediated by junctophilins essential for neuronal functions2008

    • Author(s)
      Kakizawa S, Moriguchi S, Ikeda A, Iino M, Takeshima H.
    • Journal Title

      Cerebellum 7

      Pages: 385-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP2008

    • Author(s)
      Stewart, R., Song, L., Carter, S. M., Sigalas, C., Zaccai, N. R., Kanamarlapudi, V., Bhat, M. B., Takeshima, H., Sitsapesan, R.
    • Journal Title

      J. Membr. Biol. 222

      Pages: 65-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Journal Article] Superoxide-induced potentiation in the hippocampus requires activation of ryanodine receptor type 3 and ERK2008

    • Author(s)
      Huddleston AT, Tang W, Takeshima H, Hamilton SL, et.al.
    • Journal Title

      J. Neurophysiol 99

      Pages: 1565-1571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladdersmooth muscle.2007

    • Author(s)
      Hotta, S.・Morimura, K.・Ohya, S.・Muraki, K.・Takeshima, H.・Imaizumi, Y.
    • Journal Title

      J Physiol 582

      Pages: 489-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Mg2+ activates the ryanodine receptor type 2 (RyR2) at intermediate Ca2+ concentrations.2007

    • Author(s)
      Chugun, A・Sato, O・Takeshima, H・Ogawa, Y
    • Journal Title

      Am J Cell Phys 292

      Pages: 535-544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] ORL1 receptor-mediated down-regulation of mRER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle.2007

    • Author(s)
      Miyakawa, K・Uchida, A・Shiraki, T・Tesjo,a, K・Takeshima, H, et. al.
    • Journal Title

      Neuropharmacol 52

      Pages: 1055-1064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Mutations of junctophilin type 2 associated with hypertrophic cardiomyopathy.2007

    • Author(s)
      Matsushita, Y., Furukawa, T., Kasanuki, H., Nishibatake, M., Kurihara, Y., Ikeda, A., Kamatani, N., Takeshima, H., Matsuoka, R.
    • Journal Title

      J. Hum. Genet. 52

      Pages: 543-548

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.2007

    • Author(s)
      Kakizawa, S., Kishimoto, Y., Hashimoto, K., Miyazaki, T., Furutani, K., Shimizu, H., Fukaya, M., Nishi, M., Sakagami, H., Ikeda, A., Kondo, H., Kano, M., Watanabe, M., Iino, M., Takeshima, H.
    • Journal Title

      EMBO J. 26

      Pages: 1924-1933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Conformation-dependent staility of junctophilin 1(JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.2007

    • Author(s)
      Phimister, A.J.・Lango, J.・Lee., E.H.・Ernst-Russell, M.・Takeshima, H.・Ma, J.・Allen, P.D.・Pessah, I.N
    • Journal Title

      J. Biol. Chem 282

      Pages: 8667-8677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] TRIC channels are essential for Ca^<2+> handling in intracellular stores2007

    • Author(s)
      Yazawa, M., Ferrante, C., Feng, J., Mio, K., Ogura, T., Zhang, M., Lin, P-H., Pan, Z., Komazaki, S., Kato, K., Nishi, M., Zhao, X., Weisleder, N., Sato, C., Ma, J., Takeshima, H
    • Journal Title

      Nature 448

      Pages: 78-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15109005
  • [Journal Article] Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.2007

    • Author(s)
      Ikeda, A., Miyazaki, T., Kakizawac, S., Okuno, Y., Tsuchiya, S., Myomoto, A., Saito, S., Yamamoto, T., Yamazaki, T., Iino, M., Tsujimoto, G., Watanabe, M., Takeshima, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 363

      Pages: 835-839

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Calumin, a novel Ca^<2+>-binding transmembrane protein on the endoplasmic reticulum.2007

    • Author(s)
      Zhang, M., Yamazaki, T., Yazawa, M., Treves, S., Nishi, M., Murai, M., Shibata, E., Zorzato, F., Takeshima, H.
    • Journal Title

      Cell Calcium 42

      Pages: 83-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.2007

    • Author(s)
      Kakizawa S, Kishimoto Y, Hashimoto K, Miyazaki T, Furutani K, Shimizu H, Fukaya M, Nishi M, Sakagami H, Ikeda A, Kondo H, Kano M, Watanabe M, Iino M, Takeshima H.
    • Journal Title

      EMBO J. 26

      Pages: 1924-1933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.2007

    • Author(s)
      Zhang M, Yamazaki T, Yazawa M, Treves S, Nishi M, Murai M, Shibata E, Zorzato F, Takeshima H.
    • Journal Title

      Cell Calcium. 42

      Pages: 83-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Calumin, a novel Ca^<2+>-binding transmembrane protein on the endoplasmic reticulum2007

    • Author(s)
      Zhang, M., Yamazaki, T., Yazawa, M., Treves, S., Nishi, M., Muni, M., Shibata, E., Zorzato, F., Takeshima, H
    • Journal Title

      Cell Calcium 42

      Pages: 83-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15109005
  • [Journal Article] Nociceptin receptor (NOP)-deficient mice show memory and learning enhancement in a novel KUROBOX apparatus using stress-free positive cue task.2007

    • Author(s)
      Nagai, J.・Kurokawa, M.・Takeshima, H.・Kieffer, B.・L. Ueda, H
    • Journal Title

      J. Pharmacol. Exp. Ther. 321

      Pages: 195-201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] TRIC channels are essential for Ca^<2+> handling in intracellular stores.2007

    • Author(s)
      Yazawa, M., Ferrante, C., Feng, J., Mio, K., Ogura, T., Zhang, M., Lin, P-H., Pan, Z., Komazaki, S., Kato, K., Nishi, M., Zhao, X., Weisleder, N., Sato, C., Ma, J., Takeshima, H.
    • Journal Title

      Nature 448

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Systemic ablation of RyR3 Ca2+ spark signaling in adult skeletal muscle.2007

    • Author(s)
      Weisleder, N.・Ferrante, C.・Hirata, Y.・Collet, C.・Chu, Y.・Cheng, H.・Takeshima, H.・Ma, J
    • Journal Title

      Cell Calcium 42

      Pages: 548-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] TRIC channels are essential for Ca2+ handling in intracellular stores.2007

    • Author(s)
      Yazawa M, Ferrante C, Feng J, Mio K, Ogura T, Zhang M, Lin P-H, Pan Z, Komazaki S, Kato K, Nishi M, Zhao X, Weisleder N, Sato C, Ma J, Takeshima H.
    • Journal Title

      Nature. 448

      Pages: 78-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins2007

    • Author(s)
      Ikeda, A., Miyazaki, T., Kakizawac, S., Okuno, Y., Tsuchiya, S., Myomoto, A., Saito, S., Yamamoto, T., Yamazaki, T., lino, M., Tsujimoto, G., Watanabe, M., Takeshima, H
    • Journal Title

      Biochem. Biophys. Res. Commun 363

      Pages: 835-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15109005
  • [Journal Article] Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.2006

    • Author(s)
      Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, Saito S, Watanabe M, Kondo H, Yawo H, Fukunaga K, Takeshima H.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 103

      Pages: 10811-10816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Uncoupling of store-operated Ca^<2+> entry and altered Ca^<2+> release from sarcoplasmic reticulum through silencing of junctophilins.2006

    • Author(s)
      Hirata, Y., Brotto, M., Weisleder, N., Chu, Y., Lin, P., Zhao, X., Thornton, A., Komazaki, S., Takeshima, H., Ma, J., Pan, Z.
    • Journal Title

      Biophys. J. 90

      Pages: 4418-4427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Functional uncoupling between Ca^<2+> release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.2006

    • Author(s)
      Moriguchi, S., Nishi, M., Komazaki, S., Sakagami, H., Miyazaki, T., Masumiya, H., Saito, S., Watanabe, M., Kondo, H., Yawo, H., Fukunaga, K., Takeshima, H.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 10811-10816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Journal Article] Impaired cerebellar functions in mutant mice lacking DNER.2006

    • Author(s)
      Togho A, Eiraku M, Miyazaki T, Miura E, Kawaguchi S, Nishi M, Watanabe M, Hirano T, Kengaku M, Takeshima H.
    • Journal Title

      Mol.Cell.Neurosci. 31

      Pages: 326-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release.2006

    • Author(s)
      Weisleder N, Brotto M, Komazaki S, Pan Z, Zhao X, Nosek T, Parness J, Takeshima H, Ma J.
    • Journal Title

      J.Cell Biol. 174

      Pages: 639-645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice.2005

    • Author(s)
      Yoshida M, Minamisawa S, Komazaki S, Shimura M, Kume H, Zhang M, Matsumura K, Nishi M, Saito M, Ishikawa Y, Yanagisawa T, Takeshima H.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 3500-3506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Journal Article] Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies.2004

    • Author(s)
      Minamisawa S, Oshikawa J, Takeshima H, Hoshijima M, Wang Y, Chien KR, Ishikawa Y, Matsuoka R
    • Journal Title

      Biochem.Biophys.Res.Commun. 325

      Pages: 852-856

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Exogenous, but not endogenous nociceptin modulates mesolimbic dopamine release in mice.2004

    • Author(s)
      Koizumi M, Midorikawa N, Takeshima H, Murphy NP.
    • Journal Title

      J Neurochem. 89

      Pages: 257-263

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Co-expression of mg29 and ryanodine receptor leads to apoptotic cell death-effect mediated by intracellular Ca^<2+> release.2004

    • Author(s)
      Pan Z, Hirata Y, Nagaraj RY, Zhao J, Nishi M, Hayek SM, Bhat MB, Takeshima H, Ma J.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 19387-19390

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Lack of nociceptin receptor alters body temperature during the resting period m mice.2004

    • Author(s)
      Uezu K, Sei H, Sano A, Toida K, Suzuki-Yamamoto T, Houtani T, Sugimoto T, Takeshima H., Ishimura K, Morita Y.
    • Journal Title

      Neuroneport 15

      Pages: 751-755

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Defective maintenance of intracellular Ca^<2+> homeostasis is linked to increased muscle fatigability in the MG29 null mice.2004

    • Author(s)
      Brotto MA, Nagaraj RY, Brotto LS, Takeshima H, Ma J, Nosek TM.
    • Journal Title

      Cell Res. 14

      Pages: 373-378

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis.2004

    • Author(s)
      Sakakibara T, Nemoto Y, Nukiwa T, Takeshima H.
    • Journal Title

      FEBS Lett. 566

      Pages: 294-300

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Intradermal nociceptin elicits itch-associated responses through leukotriene B4 in mice2004

    • Author(s)
      Andoh T, Yageta Y, Takeshima H, Kuraishi Y.
    • Journal Title

      J.Invest.Dermatol. 123

      Pages: 196-201

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Junctophilins : a novel family of junctional membrane complex proteins.2000

    • Author(s)
      Takeshima H, et al.
    • Journal Title

      Mol.Cell 6

      Pages: 11-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Junctophilins : a novel family of junctional membrane complex proteins.2000

    • Author(s)
      Takeshima H, et al.
    • Journal Title

      Mol. Cell 6

      Pages: 11-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144210
  • [Journal Article] Impaired Ca^<2+> store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice.

    • Author(s)
      Yoshida M, Minamisawa S, et al. Yanagisawa T, Takeshima H.
    • Journal Title

      J.Biol.Chem. (in press)

    • Data Source
      KAKENHI-PROJECT-12144210
  • [Presentation] 心臓におけるTRIC-Aの機能2021

    • Author(s)
      竹島浩
    • Organizer
      日本生理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02597
  • [Presentation] Intracellular TRIC channels: electrophysiological and pathophysiological characterization.2017

    • Author(s)
      Takeshima H.
    • Organizer
      Gordon Research Conference; Organellar channels & transporters
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04676
  • [Presentation] TRIC channels are essential partners for Ca^<2+> release2012

    • Author(s)
      Takeshima, H
    • Organizer
      European Calcium Channel Conference
    • Place of Presentation
      Alpbach, Austria
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Presentation] TRIC channels supporting physiological Ca^<2+> release2012

    • Author(s)
      Takeshima, H
    • Organizer
      Gordon Research Conference; muscle E-C coupling
    • Place of Presentation
      Les Diablerets, Switzerland
    • Year and Date
      2012-06-04
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Presentation] TRIC channel subtypes, willing partners with Ca^<2+> release channels in intracellular stores2011

    • Author(s)
      Takeshima, H
    • Organizer
      Gordon Research Conference; Ca^<2+> signaling
    • Place of Presentation
      Waterville Valley, USA
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Presentation] TRIC channel subtypes, willing partners with Ca2+ release channels in intracellular stores2011

    • Author(s)
      Takeshima, H.
    • Organizer
      Gordon Research Conference ; Ca2+ signaling
    • Place of Presentation
      Watervilie Valley, USA(招待講演)
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Presentation] Immuno-proteomic approach to E-C coupling : junctophilin and TRIC channel in cardiac Ca^<2+> release2010

    • Author(s)
      Takeshima, H.
    • Organizer
      IUPS satellite symposium
    • Place of Presentation
      ホテルフジタ(京都)
    • Year and Date
      2010-07-28
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Presentation] TRIC channel subtypes and SR/ER Ca^<2+> release.2009

    • Author(s)
      Takeshima, H.
    • Organizer
      Gordon Research Conference; Muscle Excitation-Contraction Coupling
    • Place of Presentation
      in Waterville Valley, USA
    • Year and Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Presentation] Immuno-proteomic approach to E-C coupling : junctophilin and TRIC channel in cardiac Ca2+ release2009

    • Author(s)
      Takeshima H.
    • Organizer
      IUPS Whole-day Symposium.
    • Place of Presentation
      Kyoto.
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Presentation] Molecular components supporting ryanodine receptor-mediated Ca^<2+> release : roles of junctophilin and TRIC channel in cardiac Ca^<2+> release."2009

    • Author(s)
      Takeshima, H.
    • Organizer
      JST Japan-Mexico Scientific Workshop
    • Place of Presentation
      in Universidad Nacional Autonoma de Mexico (UNAM), Mexico City
    • Year and Date
      2009-02-25
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Presentation] Immuno-proteomic approach to E-C coupling: junctophilin and TRIC channel in cardiac Ca^<2+> release2009

    • Author(s)
      Takeshima, H.
    • Organizer
      IUPS Whole-day Symposium
    • Place of Presentation
      in Kyoto
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Presentation] TRIC channel subtypes and SR/ER Ca^<2+> release. Gordon Research Conference.2009

    • Author(s)
      Takeshima, H.
    • Organizer
      Muscle Excitation-Contraction Coupling
    • Place of Presentation
      in Waterville Valley, USA.
    • Year and Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Presentation] TRIC channel subtypes and SR/ER Ca2+ release.2009

    • Author(s)
      Hiroshi Takeshima
    • Organizer
      Gordon Research Conference ; Muscle Excitation-Contraction Coupling.
    • Place of Presentation
      Waterville Valley, USA.
    • Year and Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-20249004
  • [Presentation] Ryanodine receptor-mediated Ca2+ release from muscle sarcoplasmic reticulum2006

    • Author(s)
      Takeshima H.
    • Organizer
      Gordon Research Conference ; Muscle Excitation-Contraction Coupling.
    • Place of Presentation
      New London, USA.
    • Year and Date
      2006-06-09
    • Data Source
      KAKENHI-PROJECT-17081015
  • [Presentation] Ryanodine receptor-mediated Ca^<2+> release from sarcoplasmic reticulum2006

    • Author(s)
      Takeshima, H.
    • Organizer
      Gordon Research Conference; Muscle Excitation-Contraction Coupling
    • Place of Presentation
      in New London, USA
    • Year and Date
      2006-06-09
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Presentation] Mitsugumins, a series of novel membrane proteins in skeletal muscle2006

    • Author(s)
      Takeshima, H.
    • Organizer
      Muscle Symposium in Basel
    • Place of Presentation
      in Basel, Switzerland
    • Year and Date
      2006-05-05
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Presentation] Junctophilin-mediated channel coupling during muscle E-C coupling2005

    • Author(s)
      Takeshima, H.
    • Organizer
      European Muscle Conference
    • Place of Presentation
      in Debrecen, Hungary
    • Year and Date
      2005-09-17
    • Data Source
      KAKENHI-PROJECT-17081001
  • [Presentation] TRIC channels supporting physiological Ca2+ release.

    • Author(s)
      Hiroshi Takeshima
    • Organizer
      Gordon Research Conference; muscle E-C coupling
    • Place of Presentation
      Les Diablerets, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-23240055
  • [Presentation] TRIC channels and vascular tonus

    • Author(s)
      Takeshima, H.
    • Organizer
      Gordon Research Conference; Ca2+ signaling
    • Place of Presentation
      Tuscany Il Ciocco Resorts, Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-23240055
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