HIROSE Mayumi 廣瀬まゆみ

… Alternative Names

廣瀬まゆみヒロセマユミ

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Researcher Number	00353524
Other IDs
Affiliation (based on the past Project Information) *help	2013: 金沢大学, がん進展制御研究所, 博士研究員 2011 – 2013: 金沢大学, がん進展制御研究所, 研究員 2008: 阪大, たんぱく質研究所 2005 – 2006: 大阪大学, 蛋白質研究所, 特任研究員 2004: (財)大阪バイオサイエンス研究所, 分子生物学部門, 研究員
Review Section/Research Field	Principal Investigator Digestive surgery / Pathobiological dentistry/Dental radiology / Biological Sciences / Biological pharmacy
Keywords	Principal Investigator X線結晶構造解析 / 薬剤スクリーニング / 抗がん剤 / GSK3β / 細胞増殖 / 細胞運動 / 医薬品 / Drug repositioning / GSK3beta / すい臓がん … More / 大腸がん / 消化器がん / Paxillin / 創薬 / NMR / 癌転移 / SH3ドメイン / Cortactin / AMAP1 / リン酸化タンパク質 / リン酸化蛋白質 / パキシリン Less

Therapeutic effect of the GSK3beta-inhibiting drugs against gastrointestinal cancer and the elucidation of a molecular mechanismPrincipal Investigator
- Principal Investigator
  
  HIROSE Mayumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
歯周病原因蛋白質FimAの歯周病進行抑制薬の開発に向けた構造解析Principal Investigator
- Principal Investigator
  
  廣瀬まゆみ
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka University
PIP2依存性ArfGAPタンパク質による形質膜制御機構の解明Principal Investigator
- Principal Investigator
  
  廣瀬まゆみ
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
癌転移抑制剤の標的タンパク質・パキシリンのX線結晶構造解析Principal Investigator
- Principal Investigator
  
  廣瀬まゆみ
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
  Osaka Bioscience Institute

All 2014 2013 2011 2007 2004

All Journal Article Presentation

[Journal Article] Aberrant glycogen synthase kinase 3 beta is involved in pancreatic cancer cell invasion and resistance to therapy2013
- Author(s)
  Kitano ., Shimasaki T, Chikano Y, Nakada M, Hirose M, Higashi T, Ishigaki Y, Endo Y, Takino T, Sato H, Sai Y, Miyamoto K, Motoo Y, Minamoto T
- Journal Title
  
  PLoS One
  
  Volume: 8巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591955
[Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy2013
- Author(s)
  Kitano A
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 2 Pages: 15-15
- DOI
  10.1371/journal.pone.0055289
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-22790542, KAKENHI-PUBLICLY-23120703, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23590356, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-25460793, KAKENHI-PROJECT-25670572
[Journal Article] Elevation of rat plasma P-selectin in acute lung injury.2007
- Author(s)
  Mayumi Hirose
- Journal Title
  
  Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772・3
  
  Pages: 382-389
- Data Source
  KAKENHI-PROJECT-17048032
[Journal Article] Regulation of Bin1 SH3 domain binding by phosphoinositides.2004
- Author(s)
  Kojima C., Hashimoto A., Yabuta I., Hirose M., Hashimoto S., Kanaho Y., Sumimoto H., Ikegami T., Sabe H.
- Journal Title
  
  EMBO J 23
  
  Pages: 4413-4422
- Data Source
  KAKENHI-PROJECT-16790069
[Presentation] Therapeutic effect of the cocktail of GSK3β-inhibiting drugs against colon cancer2014
- Author(s)
  Mayumi Hirose, Takahiro Domoto, Toshinari Minamoto
- Organizer
  金沢国際がん生物学シンポジウム＆アカデミア創薬シンポジウム
- Place of Presentation
  金沢・エクセル東急
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Therapeutic effect of the cocktail of GSK3beta-inhibiting drugs against colon cancer2014
- Author(s)
  Mayumi Hirose, Takahiro Domoto, Toshinari Minamoto
- Organizer
  金沢国際がん生物学シンポジウム&アカデミア創薬シンポジウム
- Place of Presentation
  金沢・エクセル東急
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] GSK3β阻害作用を有する医薬品の大腸がんに対する治療効果2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、源利成
- Organizer
  第７２回日本癌学界学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Putative pathological role of GSK3beta in aberrant glucose metabolism in colon cancer cells:大腸がん細胞の糖代謝特性におけるGSK3betaの病的作用2013
- Author(s)
  Domoto Takahiro1, Mayumi Hirose, Tomoyoshi Soga, Hiroyasu Esumi, Toshinari Minamoto
- Organizer
  第72回日本癌学界学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] SK3betaを標的とした既存医薬品を用いた大腸がん治療の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
- Organizer
  第78回大腸癌研究会
- Place of Presentation
  東京・都市センターホテル
- Year and Date
  2013-01-18
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 既存医薬品を用いたGSK3beta阻害による大腸がん治療法の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、伊藤友美、源利成
- Organizer
  第24回日本消化器癌発生学会総会
- Place of Presentation
  金沢・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 大腸がんの糖代謝経路におけるGSK3betaの機能解析2013
- Author(s)
  堂本貴寛、廣瀬まゆみ、紙健次郎、曽我朋義、江角浩安、源利成
- Organizer
  第24回日本消化器癌発生学会総会
- Place of Presentation
  金沢・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Therapeutic effect of the GSK3beta-inhibiting drugs against colon cancer:GSK3beta阻害作用を有する医薬品の大腸がんに対する治療効果2013
- Author(s)
  Mayumi Hirose, Yumi Ito, Takahiro Domoto , Toshinari Minamoto
- Organizer
  第72回日本癌学界学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Therapeutic effect of GSK3β inhibition by drugs in clinical use against colon and pancreatic cancer2013
- Author(s)
  Mayumi Hirose, Takahiro Domoto, Yumi Ito, Kazuyuki Kawakami, Toshinari Minamoto:
- Organizer
  第３回発がんスパイラル国際シンポジウム　＆　金沢国際がん生物学シンポジウム
- Place of Presentation
  石川県（金沢エクセルホテル東急）
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 既存医薬品を用いたGSKβ阻害による大腸がん治療法の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、源利成
- Organizer
  第２４回日本消化器癌発生学会総会
- Place of Presentation
  金沢・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] GSK3βを標的とした既存医薬品を用いた大腸がん治療の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
- Organizer
  第 78 回大腸癌研究会
- Place of Presentation
  東京都（都市センターホテル）
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 大腸がんの糖代謝経路におけるGSKβの機能解析2013
- Author(s)
  堂本貴寛、廣瀬まゆみ、紙健次郎、曽我朋義、江角浩安、源利成
- Organizer
  第２４回日本消化器癌発生学会総会
- Place of Presentation
  金沢・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 大腸がん細胞の糖代謝特性におけるGSK3β の病的作用2013
- Author(s)
  堂本貴寛、廣瀬まゆみ、曽我朋義、江角浩安、源利成
- Organizer
  第７２回日本癌学界学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Glycogen synthase kinase (GSK) 3βは神経膠芽腫の浸潤を促進する2011
- Author(s)
  近野祐里、ほか、廣瀬まゆみ、川上和之、源利成
- Organizer
  第７０回日本がん学会総会学術集会
- Place of Presentation
  名古屋国際会議場、愛知
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Deregulated glycogen synthase kinase (GSK) 3β participates in invasion of glioblastoma.2011
- Author(s)
  Chikano Y, Hirose M, et al., Kawakami K, MInamoto T
- Organizer
  The 6th International Symposium of Institute Network
- Place of Presentation
  東京医科歯科大学、東京
- Data Source
  KAKENHI-PROJECT-23591955

1. MINAMOTO Toshinari (50239323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
2. KAWAKAMI Kazuyuki (00293358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 中川敦史 (20188890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIROSE Mayumi 廣瀬 まゆみ

廣瀬 まゆみ ヒロセ マユミ

Research Projects

Research Products

Co-Researchers

Therapeutic effect of the GSK3beta-inhibiting drugs against gastrointestinal cancer and the elucidation of a molecular mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

歯周病原因蛋白質FimAの歯周病進行抑制薬の開発に向けた構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PIP2依存性ArfGAPタンパク質による形質膜制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌転移抑制剤の標的タンパク質・パキシリンのX線結晶構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Aberrant glycogen synthase kinase 3 beta is involved in pancreatic cancer cell invasion and resistance to therapy2013

Author(s)

Journal Title

Data Source

[Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy2013

Author(s)

Journal Title

DOI

URL

Data Source

[Journal Article] Elevation of rat plasma P-selectin in acute lung injury.2007

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of Bin1 SH3 domain binding by phosphoinositides.2004

Author(s)

Journal Title

Data Source

[Presentation] Therapeutic effect of the cocktail of GSK3β-inhibiting drugs against colon cancer2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Therapeutic effect of the cocktail of GSK3beta-inhibiting drugs against colon cancer2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] GSK3β阻害作用を有する医薬品の大腸がんに対する治療効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Putative pathological role of GSK3beta in aberrant glucose metabolism in colon cancer cells:大腸がん細胞の糖代謝特性におけるGSK3betaの病的作用2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SK3betaを標的とした既存医薬品を用いた大腸がん治療の開発2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 既存医薬品を用いたGSK3beta阻害による大腸がん治療法の開発2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 大腸がんの糖代謝経路におけるGSK3betaの機能解析2013

Author(s)

HIROSE Mayumi 廣瀬まゆみ

廣瀬まゆみヒロセマユミ