Morita Rimpei 森田林平

… Alternative Names

MORITA Rimpei 森田林平

森田林平モリタリンペイ

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Researcher Number	00362541
Other IDs
Affiliation (Current)	2025: 日本医科大学, 大学院医学研究科, 大学院教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 日本医科大学, 大学院医学研究科, 大学院教授 2018 – 2019: 日本医科大学, 大学院医学研究科, 大学院教授 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 准教授 2015: 慶應義塾大学, 医学部, 准教授 2010 – 2014: 慶應義塾大学, 医学部, 講師 2005: 京大, 医学(系)研究科(研究院) 2004: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態)
Review Section/Research Field	Principal Investigator Hematology / Basic Section 49070:Immunology-related / Experimental pathology / Biological Sciences / Immunology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator NLRP3 / マクロファージ / 自然免疫 / 免疫学 / インフラマソーム / 炎症 / サイトカイン / リンパ球 / 樹状細胞 / エンドサイトーシス … More / クラスリン / タンパク翻訳後修飾 / BTK / リン酸化修飾 / タンパク相互作用 / 腫瘍 / アクチン / ミトコンドリア / プログラム細胞死 / 血管内皮細胞 / エピジェネティクス / 転写因子 / 造血幹細胞 / XLA / Btk / インフラマゾーム / IFN-γ / Treg / Th17 / IL-21 / SOCS1 / 抗体産生 / NO / 心房性ナトリウム利尿ペプチド / cGMP … More Except Principal Investigator type2炎症 / 腸内カンジダ / 好酸球性鼻副鼻腔炎 / 開放骨折 / 持続洗浄 / 骨感染症 / 遊離骨片 / gentamicin / local antibiotics / irrigation / iSAP / iMAP / CLAP / osteomyelitis / infection Less

ヒト好酸球性鼻副鼻腔炎病態でのtype２炎症と腸内カンジダ増殖の関連についての研究
- Principal Investigator
  
  松根彰志
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nippon Medical School
開放骨折への即時骨接合＋局所抗生剤高濃度持続投与法の感染率低下、遊離骨片温存作用
- Principal Investigator
  
  佐藤陽介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nippon Medical School
Elucidating of molecular mechanism by which endocytosis regulates NLRP3 inflammasome formation and its phycological significancePrincipal Investigator
- Principal Investigator
  
  森田林平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Nippon Medical School
Elucidation of physiological roles of NLRP3 phosphorylation in the NLRP3 inflammasome formationPrincipal Investigator
- Principal Investigator
  
  Morita Rimpei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Nippon Medical School
  Keio University
Direct reprogramming of human fibroblasts into hematopoietic cells mainly using ETV2Principal Investigator
- Principal Investigator
  
  Morita Rimpei
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
ＴＬＲシグナルはＢｔｋを介してＮＬＲＰ３インフラマゾームの活性化を制御するのか？Principal Investigator
- Principal Investigator
  
  森田林平
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
To elucidate the roles of SOCS1 to regulate the differentiation of follicular helper T cellsPrincipal Investigator
- Principal Investigator
  
  MORITA Rimpei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Keio University
心房性ナトリウム利尿ペプチドによる樹状細房を中心とした免疫調整作用の解析Principal Investigator
- Principal Investigator
  
  森田林平
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] 日本臨牀増刊号　再生医療2015
- Author(s)
  森田林平、笠原秀範、吉村昭彦
- Total Pages
  584
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-26670470
[Book] ダイレクトリプログラミング　（第3章　線維芽細胞→血管内皮細胞）2015
- Author(s)
  森田林平、笠原秀範、吉村昭彦
- Total Pages
  11
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-26670470
[Book] 細胞工学別冊　ダイレクトリプログラミング2015
- Author(s)
  森田林平、笠原秀範、吉村昭彦
- Total Pages
  119
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-26670470
[Journal Article] Cytoplasmic and nuclear DROSHA in human villous trophoblasts2024
- Author(s)
  Noguchi Syunya、Ohkura Sadayuki、Negishi Yasuyuki、Tozawa Shohei、Takizawa Takami、Morita Rimpei、Takahashi Hironori、Ohkuchi Akihide、Takizawa Toshihiro
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 162 Pages: 104189-104189
- DOI
  10.1016/j.jri.2023.104189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16843, KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-20K09611
[Journal Article] Characterization of Megabat-Favored, CA-Dependent Susceptibility to Retrovirus Infection2023
- Author(s)
  Ohkura Sadayuki、Horie Masayuki、Shimizu Masumi、Nakagawa So、Osanai Haruka、Miyagawa Yoshitaka、Morita Rimpei
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 3
- DOI
  10.1128/jvi.01803-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-23K06503
[Journal Article] CD8+ T Cell-Mediated Therapeutic Antitumor Effect of an Herbal Mixture Containing Ganoderma lucidum2023
- Author(s)
  Takaku Shun、Shimizu Masumi、Morita Rimpei
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2023 Issue: 1 Pages: 1-11
- DOI
  10.1155/2023/9630816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07140
[Journal Article] Anti-human-TIGIT agonistic antibody ameliorates autoimmune diseases by inhibiting Tfh and Tph cells and enhancing Treg cells2023
- Author(s)
  Kojima Marenori、Suzuki Katsuya、Takeshita Masaru、Ohyagi Masaki、Iizuka Mana、Yamane Humitsugu、Koga Keiko、Kouro Taku、Kassai Yoshiaki、Yoshihara Tomoki、Adachi Ryutaro、Hashikami Kentarou、Ota Yuichiro、Yoshimoto Keiko、Kaneko Yuko、Morita Rimpei、Yoshimura Akihiko、Takeuchi Tsutomu
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 500-500
- DOI
  10.1038/s42003-023-04874-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-22K08527
[Journal Article] TSLP in DRG neurons causes the development of neuropathic pain through T cells2023
- Author(s)
  Ino Yuka、Maruyama Motoyo、Shimizu Masumi、Morita Rimpei、Sakamoto Atsuhiro、Suzuki Hidenori、Sakai Atsushi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 20 Issue: 1 Pages: 200-200
- DOI
  10.1186/s12974-023-02882-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19463, KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-23K08415, KAKENHI-PROJECT-23K27493
[Journal Article] Japanese Kampo Medicine Juzentaihoto Improves Antiviral Cellular Immunity in Tumour-Bearing Hosts2022
- Author(s)
  Takaku S, Shimizu M, Morita R.
- Journal Title
  
  Evid Based Complement Alternat Med .
  
  Volume: 2022 Pages: 6122955-6122955
- DOI
  10.1155/2022/6122955
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-17K09328
[Journal Article] Inflammation in preterm birth: Novel mechanism of preterm birth associated with innate and acquired immunity2022
- Author(s)
  Negishi Y, Shima Y, Kato M, Ichikawa T, Ino H, Horii Y, Suzuki S, Morita R.
- Journal Title
  
  J Reprod Immunol .
  
  Volume: 154 Pages: 103748-103748
- DOI
  10.1016/j.jri.2022.103748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-22K07853, KAKENHI-PROJECT-22K16887, KAKENHI-PROJECT-20K09679
[Journal Article] Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta2022
- Author(s)
  Junxiao Wang, Syunya Noguchi, Takami Takizawa, Yasuyuki Negishi, Rimpei Morita, Shan-Shun Luo, Toshihiro Takizawa
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 158 Issue: 1 Pages: 65-78
- DOI
  10.1007/s00418-022-02109-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09611, KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-22K16843
[Journal Article] A combination of check-point blockade and α-galactosylceramide elicits long-lasting suppressive effects on murine hepatoma cell growth in vivo.2020
- Author(s)
  Ishii K, Shimizu M, Kogo H, Negishi Y, Tamura H, Morita R, Takahashi H.
- Journal Title
  
  Immunobiology
  
  Volume: 225 Pages: 151860-151860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Distribution of dendritic cells in the septate uterus: An immunological perspective.2020
- Author(s)
  Negishi Y1,2, Kato M2, Ono S2, Kuwabara Y2, Morita R1, Takahashi H1, Takeshita T2.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: e13241 Issue: 6
- DOI
  10.1111/aji.13241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09304, KAKENHI-PROJECT-16H05178
[Journal Article] Multi-dimensional analysis identified rheumatoid arthritis-driving pathway in human T cell.2019
- Author(s)
  Takeshita M, Suzuki K, Kondo Y, Morita R, Okuzono Y, Koga K, Kassai Y, Gamo K, Takiguchi M, Kurisu R, Mototani H, Ebisuno Y, Yoshimura A, Takeuchi T
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 78 Issue: 10 Pages: 1346-1356
- DOI
  10.1136/annrheumdis-2018-214885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis.2019
- Author(s)
  Kondo Y, Suzuki K, Inoue Y, Sakata K, Takahashi C, Takeshita M, Kassai Y, Miyazaki T, Morita R, Niki Y, Kaneko Y, Yasuoka H, Yamaoka K, Yoshimura A, Takeuchi T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 21 Issue: 1 Pages: 14-14
- DOI
  10.1186/s13075-018-1802-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018
- Author(s)
  Taisuke Kondo Yuki Imura Shunsuke Chikuma Sana Hibino Setsuko Omata‐Mise Makoto Ando Takashi Akanuma Mana Iizuka Ryota Sakai Rimpei Morita Akihiko Yoshimura
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2130-2140
- DOI
  10.1111/cas.13648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15290, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-16H05178
[Journal Article] Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.2018
- Author(s)
  Tasaki S, Suzuki K, Kassai Y, Takeshita M, Murota A, Kondo Y, Ando T, Nakayama Y, Okuzono Y, Takiguchi M, Kurisu R, Miyazaki T, Yoshimoto K, Yasuoka H, Yamaoka K, Morita R, Yoshimura A, Toyoshiba H, Takeuchi T.
- Journal Title
  
  Nat Commun
  
  Volume: 9(1) Issue: 1 Pages: 2755-2755
- DOI
  10.1038/s41467-018-05044-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09905, KAKENHI-PROJECT-16H05178
[Journal Article] Mafb prevents excess inflammation after ischemic stroke by accelerating clearance of danger signals through MSR1.2017
- Author(s)
  1)Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.
- Journal Title
  
  Nat Med.
  
  Volume: in press Issue: 6 Pages: 723-732
- DOI
  10.1038/nm.4312
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01387, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16H05178, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-17K19571, KAKENHI-PUBLICLY-17H05514, KAKENHI-PROJECT-17H05096, KAKENHI-PROJECT-16H06276
[Journal Article] Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy2017
- Author(s)
  Taisuke Kondo, Rimpei Morita, Yuumi Okuzono, Hiroko Nakatsukasa, Takashi Sekiya, Shunsuke Chikuma, Takashi Shichita, Mitsuhiro Kanamori, Masato Kubo, Keiko Koga, Takahiro Miyazaki, Yoshiaki Kassai, Akihiko Yohimura
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 15338-15338
- DOI
  10.1038/ncomms15338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0114, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-16H05178, KAKENHI-PROJECT-17H07088
[Journal Article] Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren's syndrome.2017
- Author(s)
  Tasaki S1,2, Suzuki K3, Nishikawa A3, Kassai Y4, Takiguchi M4, Kurisu R4, Okuzono Y4, Miyazaki T4,5, Takeshita M3, Yoshimoto K3, Yasuoka H3, Yamaoka K3, Ikeura K6, Tsunoda K6, Morita R7, Yoshimura A7, Toyoshiba H1, Takeuchi T3.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 76 Issue: 8 Pages: 1458-1466
- DOI
  10.1136/annrheumdis-2016-210788
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09905, KAKENHI-PROJECT-17K11853, KAKENHI-PROJECT-16H05178
[Journal Article] Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis.2016
- Author(s)
  Akiyama M, Suzuki K, Kassai Y, Miyazaki T, Morita R, Yoshimura A, Takeuchi T.
- Journal Title
  
  Int J Rheum Dis.
  
  Volume: 19 Issue: 4 Pages: 430-432
- DOI
  10.1111/1756-185x.12725
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Identification of definitive serum biomarkers associated with disease activity in primary Sjogren's syndrome.2016
- Author(s)
  Nishikawa A, Suzuki K, Kassai Y, Gotou Y, Takiguchi M, Miyazaki T, Yoshimoto K, Yasuoka H, Yamaoka K, Morita R, Yoshimura A, Takeuchi T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 18 Issue: 1 Pages: 106-106
- DOI
  10.1186/s13075-016-1006-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05178, KAKENHI-PROJECT-16K09905
[Journal Article] Serum proteomic analysis identifies interleukin 16 as a biomarker for clinical response during early treatment of rheumatoid arthritis.2016
- Author(s)
  Murota A, Suzuki K, Kassai Y, Miyazaki T, Morita R, Kondo Y, Takeshita M, Niki Y, Yoshimura A, Takeuchi T.
- Journal Title
  
  Cytokine.
  
  Volume: 78 Pages: 87-93
- DOI
  10.1016/j.cyto.2015.12.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Enhanced IgG4 production by follicular helper 2 T cells and the involvement of follicular helper 1 T cells in the pathogenesis of IgG4-related disease.2016
- Author(s)
  Akiyama M, Yasuoka H, Yamaoka K, Suzuki K, Kaneko Y, Kondo H, Kassai Y, Koga K, Miyazaki T, Morita R, Yoshimura A, Takeuchi T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 18 Issue: 1
- DOI
  10.1186/s13075-016-1064-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05178
[Journal Article] Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells2015
- Author(s)
  Sekiya T, Kondo T, Shichita T, Morita R, Ichinose H, Yoshimura A
- Journal Title
  
  J Exp Med.
  
  Volume: 212 Issue: 10 Pages: 1623-1640
- DOI
  10.1084/jem.20142088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01387, KAKENHI-PUBLICLY-15H01422, KAKENHI-PROJECT-14J07006, KAKENHI-PROJECT-26670470, KAKENHI-PROJECT-26870571, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-25221305
[Journal Article] ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.2015
- Author(s)
  Morita R, Suzuki M, Kasahara H, Shimizu N, Shichita T, Sekiya T, Kimura A, Sasaki K, Yasukawa H, Yoshimura A.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 1 Pages: 160-165
- DOI
  10.1073/pnas.1413234112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-26461137, KAKENHI-PROJECT-26670470
[Journal Article] Innate-like function of memory Th17 cells for enhancing endotoxin-induced acute lung inflammation through IL-22.2015
- Author(s)
  Sakaguchi R, Chikuma S, Shichita T, Morita R, Sekiya T, Ouyang W, Ueda T, Seki H, Morisaki H, Yoshimura A
- Journal Title
  
  Int Immunol.
  
  Volume: 28 Issue: 5 Pages: 233-243
- DOI
  10.1093/intimm/dxv070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01387, KAKENHI-PROJECT-13J01369, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16H05178
[Journal Article] Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production2014
- Author(s)
  Kimura A, Abe H, Tsuruta S, Chiba S, Fujii-Kuriyama Y, Sekiya T, Morita R, Yoshimura A.
- Journal Title
  
  Int Immunol.
  
  Volume: 26 Issue: 4 Pages: 209-220
- DOI
  10.1093/intimm/dxt067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-25860324, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-25221305
[Journal Article] Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN-Y expression and inducing IL-222014
- Author(s)
  Abe H, Kimura A, Tsuruta S, Fukaya T, Sakaguchi R, et al.
- Journal Title
  
  Int Immunol.
  
  Volume: 26 Issue: 3 Pages: 129-137
- DOI
  10.1093/intimm/dxt049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08459, KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-25221305
[Journal Article] Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.2013
- Author(s)
  Sekiya T, Kashiwagi I, Yoshida R, Fukaya T, et al.
- Journal Title
  
  Nat Immunol.
  
  Volume: 14 Issue: 3 Pages: 230-237
- DOI
  10.1038/ni.2520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08459, KAKENHI-PROJECT-21500305, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23790346, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-25670233
[Journal Article] TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity.2013
- Author(s)
  Muto G, Kotani H, Kondo T, Morita R, Tsuruta S, Kobayashi, T., Luche H, Fehling HJ, Walsh M, Choi Y, Yoshimura A.
- Journal Title
  
  PLoS One
  
  Volume: 8 (9) Issue: 9 Pages: e74639-e74639
- DOI
  10.1371/journal.pone.0074639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590573, KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25460132, KAKENHI-PROJECT-25670234
[Journal Article] IL-23-Independent Induction of IL-17 from γδT Cells and Innate Lymphoid Cells Promotes Experimental Intraocular Neovascularization2013
- Author(s)
  Hasegawa E
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 4 Pages: 1778-1787
- DOI
  10.4049/jimmunol.1202495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23592573, KAKENHI-PROJECT-23689071, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-24890232, KAKENHI-PROJECT-25670233
[Journal Article] Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways2012
- Author(s)
  Sugiyama Yuki, 他
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 4 Pages: 253-256
- DOI
  10.1093/intimm/dxr126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J04955, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23591356, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791662, KAKENHI-PUBLICLY-24117718
[Journal Article] Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation2012
- Author(s)
  Yoshida Hideyuki, 他
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Issue: 2 Pages: 234-240
- DOI
  10.1016/j.bbrc.2011.12.156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10943, KAKENHI-PROJECT-22390167, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659435
[Journal Article] Human blood CXCR5^+CD4^+ T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion2011
- Author(s)
  森田林平, 等
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 108-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590438
[Journal Article] SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.2011
- Author(s)
  Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Asakawa M, Chinen T, Yoshimura A.
- Journal Title
  
  J Exp Med.
  
  Volume: 208 Issue: 10 Pages: 2055-2067
- DOI
  10.1084/jem.20110428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791121
[Journal Article] The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells2011
- Author(s)
  Sekiya, T., et al
- Journal Title
  
  Nature Communications
  
  Volume: 2 Issue: 1 Pages: 269-269
- DOI
  10.1038/ncomms1272
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059014, KAKENHI-PROJECT-21500305, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23790346, KAKENHI-PROJECT-23390123
[Journal Article] Transcription Factor Smad-Independent T Helper 17 Cell Induction by Transforming-Growth Factor-ss Is Mediated by Suppression of Eomesodermin2011
- Author(s)
  Kenji Ichiyama, 他
- Journal Title
  
  Immunity
  
  Volume: 34 Issue: 5 Pages: 741-754
- DOI
  10.1016/j.immuni.2011.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05327, KAKENHI-PROJECT-11J02842, KAKENHI-PROJECT-11J04861, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23790545
[Journal Article] Human blood CXCR5+CD4+T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion.2011
- Author(s)
  Morita1 R, Schmitt N, Bentebibel SE, Ranganathan R, Bourdery L, Zurawski G,Foucat E, Dullaers M, Oh SK, SabzghabaeiN, Lavecchio EM, Punaro M, Pascual V,Banchereau J, Ueno H.
- Journal Title
  
  Immunity.
  
  Volume: 34 Issue: 1 Pages: 108-121
- DOI
  10.1016/j.immuni.2010.12.012
- Data Source
  KAKENHI-PROJECT-22590438
[Journal Article] Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th172011
- Author(s)
  Ryusuke Nakagawa, 他
- Journal Title
  
  Journal of Immunology
  
  Volume: 187 Issue: 9 Pages: 4611-4620
- DOI
  10.4049/jimmunol.1100649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10943, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22390167, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659435
[Journal Article] 濾胞ヘルパーT細胞の分化誘導2011
- Author(s)
  森田林平
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56 Pages: 694-699
- NAID
  40019145229
- Data Source
  KAKENHI-PROJECT-22590438
[Presentation] Downregulation of innate immune cells in postmenopausal osteoporosis: A novel osteoimmunological perspective.2024
- Author(s)
  Yasuyuki Negishi, Munehiro Naruo, Lilika Higuchi, Nozomi Ouchi, Shunji Suzuki, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Gelsolin negatively regulates NLRP3 inflammasome activation by stabilizing mitochondria.2024
- Author(s)
  Rimpei Morita, Jiyeon Lee, Masumi Shimizu, Fumiyuki Sasaki, Akihiko Yoshimura, Lark Kyun Kim
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] An aluminum-containing food additive causes cleavage of IL-18, IL-33 and gasdermin D in intestinal epithelial cells under antibiotic treatment.2024
- Author(s)
  Ayako Wakabayashi, Atsuko Owaki, Ken Iwatsuki, Etsuko Toda, Yasuhiro Nishiyama, Shoji Matsune, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Protective role of inflammatory cytokines in murine miscarriage: perspective of interleukin-18 functions.2024
- Author(s)
  Yumi Horii, Hajime Ino, Yasuyuki Negishi, Eri Koike, Shunji Suzuki, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] IL-18: immune mediator from maternal uterus to placental development.2024
- Author(s)
  Hajime Ino, Yasuyuki Negishi, Yumi Horii, Eri Koike, Richard A. Flavell, Shunji Suzuki, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Gelsolin from macrophages is required for fibroblast migration during skin wound healing2024
- Author(s)
  Eri Toyohara, Fumiyuki Sasaki, Teruyuki Dohi, Rei Ogawa, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Sphingosine-1-phosphate lyase SGPL1 is required for NLRP3 inflammasome activation via the dynamic organization of endoplasmic reticulum and microtubules.2024
- Author(s)
  Fumiyuki Sasaki, Masumi Shimizu, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] The multiple myeloma microenvironment triggers inflammasome activation in tolerogenic dendritic cells to promote disease progression.2024
- Author(s)
  Mariko Ishibashi, Mika Sunakawa, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Clathrin heavy chain regulates NLRP3 inflammasome formation via endocytosis in macrophages.2024
- Author(s)
  Hung Hiep Huynh, Fumiyuki Sasaki, Masumi Shimizu, Akihiko Yoshimura, Rimpei Morita
- Organizer
  第52回日本免疫学会学術集会（千葉）
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] The gelsolin-actin axis orchestrates NLRP3 inflammasome activation.2023
- Author(s)
  Rimpei Morita, Jiyeon Lee, Mika Sunakawa, Eri Koike, Masumi Shimizu, Mariko Ishibashi, Fumiyuki Sasaki, Akihiko Yoshimura, Lark Kyun Kim
- Organizer
  Keystone Symposia. Innate Immunity: From Innate Sensing to Adaptive Responses (D2)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Sphingosine-1-phosphate lyase promotes NLRP3 inflammasome activation via the development of endoplasmic reticulum and microtubules.2023
- Author(s)
  Fumiyuki Sasaki, Masumi Shimizu, Rimpei Morita
- Organizer
  Keystone Symposia. Innate Immunity: From Innate Sensing to Adaptive Responses (D2)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] phingosine-1-phosphate lyase promotes inflammasome activation via the development of endoplasmic reticulum network2022
- Author(s)
  Fumiyuki Sasaki, Masumi Shimizu and Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Novel function of clathrin heavy chain regulating NLRP3 inflammasome formation via endocytosis in macrophages2022
- Author(s)
  Hung Hiep Huynh, Eri Koike, Masumi Shimizu, Akihiko Yoshimura, Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Antibiotics promote epithelial cell death and eosinophilic infiltration in the gut caused by an aluminum-containing food additive2022
- Author(s)
  Ayako Wakabayashi, Atsuko Owaki, Ken Iwatsuki, Yasuhiro Nishiyama, Shoji Matsune, Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] オオコウモリTRIM5aは霊長類TRIM5aとは異なる機序によってマウス白血病ウイルス（MLV）感染を抑制する2022
- Author(s)
  小山内遥香、大倉定之、清水真澄、森田林平
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] IL-18 Regulates Immune Responses Contributing Placental Development and Fetal Growth2022
- Author(s)
  Hajime Ino, Yumi Horii, Yasuyuki Negishi, Shunji Suzuki, Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] オオコウモリ細胞では新規のcapsid依存性宿主因子がHIV-1を抑制する2022
- Author(s)
  大倉定之、清水真澄、堀江真行、中川草、小山内遥香、宮川世志幸、森田林平
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Extracellular low pH in myeloma microenvironments induces tolelogenic dendritic cells2022
- Author(s)
  Mariko Ishibashi, Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] NKT-like cell activity interferes with the pathogenesis of alcohol-induced murine osteoporosis2022
- Author(s)
  Munehiro Naruo, Yasuyuki Negishi, Takahisa Okuda, Ken Okazaki , Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Gelsolin-actin axis organizes NLRP3 inflammasome activation2022
- Author(s)
  Masumi SHIMIZU, Eri KOIKE, Jiyeon LEE, Fumiyuki SASAKI, Akihiko YOSHIMURA, Lark Kyun KIM, Rimpei MORITA
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07140
[Presentation] Notch シグナルによる活性化 T 細胞からステムセルメモリー T 細胞への転換と免疫療法への応用2017
- Author(s)
  近藤泰介、森田林平、吉村昭彦
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16H05178
[Presentation] Clathrin heavy chain is an NLRP3 partner for NLRP3 inflammasome activation2017
- Author(s)
  森田林平、吉村昭彦
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05178
[Presentation] Ｔ細胞の免疫リプログラミング2016
- Author(s)
  吉村昭彦、近藤泰介、染谷和江、岡田匡央、森田林平
- Organizer
  第１５回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場　（大阪府大阪市）
- Year and Date
  2016-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-26670470
[Presentation] Btk modulates NLRP3, but not AIM2, inflammasome activation2012
- Author(s)
  Morita Rimpei
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012
- Place of Presentation
  Tokyo
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PUBLICLY-24117718
[Presentation] Epigenetic modification induces CD8-expressing double-positive T cells from human blood CD4+ T cells2012
- Author(s)
  Morita Rimpei
- Organizer
  日本免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590438
[Presentation] Epigenetic modification induces CD8abexpressing double-positive T cells from human blood CD4+ T cells counterparts of T follicular cells2012
- Author(s)
  森田林平、吉村昭彦
- Organizer
  第41回日本免疫学会学術集会・総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590438
[Presentation] Human blood CXCR5+ CD4+ T cells are counterparts of T follicular cells2011
- Author(s)
  森田林平
- Organizer
  第40回日本免疫学会学術集会・総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22590438
[Presentation] Human blood CXCR5+ CD4+ T cells are counterparts of T follicular cells2011
- Author(s)
  森田林平
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ:千葉(国際シンポジウム)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22590438

1. YOSHIMURA Akihiko (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 佐藤陽介 (60892073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 原義明 (20386197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 平林篤志 (20643141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 横堀将司 (70449271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 秋元敏雄 (30184112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐々木文之 (10706469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 松根彰志 (00253899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大橋隆治 (00328783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大久保公裕 (10213654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 若林あや子 (30328851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 許田典男 (60614758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIMURA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YOSHIMOTO Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. SAKAI Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 七田崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
17. 関谷高史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 近藤泰介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 小林隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 野口隼矢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 丸山基世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 根岸靖幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 瀧澤俊広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 竹下俊行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 桑原慶充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morita Rimpei 森田 林平

MORITA Rimpei 森田 林平

森田 林平 モリタ リンペイ

Research Projects

Research Products

Co-Researchers

ヒト好酸球性鼻副鼻腔炎病態でのtype２炎症と腸内カンジダ増殖の関連についての研究

Principal Investigator

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開放骨折への即時骨接合＋局所抗生剤高濃度持続投与法の感染率低下、遊離骨片温存作用

Principal Investigator

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Elucidating of molecular mechanism by which endocytosis regulates NLRP3 inflammasome formation and its phycological significancePrincipal Investigator

Principal Investigator

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Review Section

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Elucidation of physiological roles of NLRP3 phosphorylation in the NLRP3 inflammasome formationPrincipal Investigator

Principal Investigator

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Direct reprogramming of human fibroblasts into hematopoietic cells mainly using ETV2Principal Investigator

Principal Investigator

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ＴＬＲシグナルはＢｔｋを介してＮＬＲＰ３インフラマゾームの活性化を制御するのか？Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

To elucidate the roles of SOCS1 to regulate the differentiation of follicular helper T cellsPrincipal Investigator

Principal Investigator

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Research Institution

心房性ナトリウム利尿ペプチドによる樹状細房を中心とした免疫調整作用の解析Principal Investigator

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[Book] 日本臨牀増刊号 再生医療2015

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[Book] ダイレクトリプログラミング （第3章 線維芽細胞→血管内皮細胞）2015

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[Book] 細胞工学別冊 ダイレクトリプログラミング2015

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[Journal Article] Cytoplasmic and nuclear DROSHA in human villous trophoblasts2024

Author(s)

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[Journal Article] Characterization of Megabat-Favored, CA-Dependent Susceptibility to Retrovirus Infection2023

Author(s)

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[Journal Article] CD8+ T Cell-Mediated Therapeutic Antitumor Effect of an Herbal Mixture Containing Ganoderma lucidum2023

Morita Rimpei 森田林平

MORITA Rimpei 森田林平

森田林平モリタリンペイ

[Book] 日本臨牀増刊号　再生医療2015

[Book] ダイレクトリプログラミング　（第3章　線維芽細胞→血管内皮細胞）2015

[Book] 細胞工学別冊　ダイレクトリプログラミング2015

[Journal Article] Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren's syndrome.2017