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Nakayama TurrentRobert  中山 タラントロバート

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Nakayama Robert  中山 タラントロバート

NAKAYAMA Robert t.  中山 タラントロバート

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Researcher Number 00365298
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help 2025: 慶應義塾大学, 医学部(信濃町), 講師
2017 – 2023: 慶應義塾大学, 医学部(信濃町), 講師
2017: 慶應義塾大学, 医学部(信濃町), 助教
2009 – 2013: Keio University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Tumor diagnosis
Except Principal Investigator
Basic Section 50010:Tumor biology-related / Orthopaedic surgery
Keywords
Principal Investigator
肉腫 / 悪性軟部腫瘍 / 骨軟部腫瘍 / 遺伝子 / 癌 / cfDNA / リキッドバイオプシー / トランスレーショナルリサーチ / 遺伝子発現制御 / SS18-SSX … More / クロマチンリモデリング複合体 / BAF / SWI/SNF / AYA世代 / 希少がん / 滑膜肉腫 / SWI/SNF複合体 / 融合遺伝子 / トランスレーショナル・リサーチ / ゲノム / 発がん / がん発現解析 / APAM17 / CD44 / 発現解析 / ADAM17 / CD4 / 転移 / 蛋白質 / シグナル伝達 … More
Except Principal Investigator
悪性末梢神経鞘腫 / 神経線維腫 / 神経鞘腫 / 腫瘍オルガノイド培養 / 骨軟部肉腫 / 整形外科 / ゲノム / 癌 / 融合遺伝子 / 骨軟部腫瘍 / がんゲノム / ゲノム解析 / 肉腫 Less
  • Research Projects

    (7 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (49 People)
  •  軟骨系腫瘍オルガノイドを用いた軟骨肉腫腫瘍化の分子機構解明と新規薬物治療開発Principal Investigator

    • Principal Investigator
      中山 タラントロバート
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Keio University
  •  末梢神経腫瘍オルガノイドを用いた腫瘍化の分子機構解明と新規薬物治療開発

    • Principal Investigator
      森 智章
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Keio University
  •  リキッドバイオプシーによる骨軟部腫瘍の病勢モニタリングの実用化を目指した研究Principal Investigator

    • Principal Investigator
      中山 タラントロバート
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Keio University
  •  Oncogenic role of aberrant SWI/SNF chromatin remodeling complex in synovial sarcomaPrincipal Investigator

    • Principal Investigator
      Nakayama Robert
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University
  •  Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma

    • Principal Investigator
      Matsuda Koichi
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  粘液線維肉腫の診断・予後関連バイオマーカーの開発Principal Investigator

    • Principal Investigator
      中山 タラントロバート
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor diagnosis
    • Research Institution
      Keio University
  •  Expression and functional analysis of CD44 and ADAM17in bone and soft tissue tumorsPrincipal Investigator

    • Principal Investigator
      NAKAYAMA Robert t.
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University

All 2023 2022 2021 2019 2018 2017 2016 2013 2012

All Journal Article Presentation

  • [Journal Article] がん遺伝子パネル検査を用いた骨軟部腫瘍のゲノム解析2023

    • Author(s)
      山口さやか, 中山ロバート
    • Journal Title

      癌と化学療法

      Volume: 50巻3号 Pages: 309-313

    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Journal Article] 骨肉腫ゲノムの多様性2021

    • Author(s)
      齊藤誠人,関田哲也,山口さやか,中山ロバート
    • Journal Title

      別冊整形外科

      Volume: 79

    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Journal Article] Pseudomyogenic hemangioendothelioma of bone treated with denosumab: a case report2019

    • Author(s)
      Otani Shinya、Nakayama Robert、Sekita Tetsuya、Hirozane Toru、Asano Naofumi、Nishimoto Kazumasa、Sasaki Aya、Okita Hajime、Morioka Hideo、Nakamura Masaya、Matsumoto Morio
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 872-872

    • DOI

      10.1186/s12885-019-6072-8

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K09637, KAKENHI-PROJECT-17K10985
  • [Journal Article] Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG03042019

    • Author(s)
      Tanaka Kazuhiro、Mizusawa Junki、Naka Norifumi、Kawai Akira、et al.
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 1-7

    • DOI

      10.1186/s12885-019-6114-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-17K10985
  • [Journal Article] The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma2018

    • Author(s)
      McBride Matthew J.、Pulice John L.、Beird Hannah C.、Ingram Davis R.、D’Avino Andrew R.、Shern Jack F.、Charville Gregory W.、Hornick Jason L.、Nakayama Robert T. et al.
    • Journal Title

      Cancer Cell

      Volume: 33 Issue: 6 Pages: 1128-1141.e7

    • DOI

      10.1016/j.ccell.2018.05.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Journal Article] Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG03042018

    • Author(s)
      Tanaka K, Ogawa G, Mizusawa J, Naka N, Kawai A, Takahashi M, Hiruma T, Matsumoto Y, Tsuchiya H, Nakayama R, Hatano H, Emori M, Hosaka M, Yoshida Y, Toguchida J, Abe S, Asanuma K, Yokoyama R, Hiraga H, Yonemoto T, Morii T, Matsumoto S, Nagano A, Yoshikawa H, Fukuda H, Ozaki T, Iwamoto Y.
    • Journal Title

      World Journal of Surgical Oncology

      Volume: 16 Issue: 1 Pages: 160-160

    • DOI

      10.1186/s12957-018-1462-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10974, KAKENHI-PROJECT-17K10985, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-17K19725
  • [Journal Article] A histological positive margin after surgery is correlated with high local re-recurrence rate in patients with recurrent myxofibrosarcoma2017

    • Author(s)
      Kikuta K, Nakayama R, Yoshida A, Sasaki A, Kameyama K, Chuman H, Kawai A, Nakamura M, Matsumoto M, Morioka H
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 47 (4) Issue: 4 Pages: 334-341

    • DOI

      10.1093/jjco/hyw199

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20017, KAKENHI-PROJECT-16H02676
  • [Journal Article] SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters2017

    • Author(s)
      Nakayama Robert T、Pulice John L、Valencia Alfredo M、McBride Matthew J、McKenzie Zachary M、Gillespie Mark A、Ku Wai Lim、Teng Mingxiang、Cui Kairong、Williams Robert T、Cassel Seth H、Qing He、Widmer Christian J、Demetri George D、Irizarry Rafael A、Zhao Keji、Ranish Jeffrey A、Kadoch Cigall
    • Journal Title

      Nature Genetics

      Volume: 49 Issue: 11 Pages: 1613-1623

    • DOI

      10.1038/ng.3958

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10985, KAKENHI-PROJECT-16H02676
  • [Journal Article] Wide-spread ignorance on the treatment of subcutaneous malignant tumors; a questionnaire-based study2017

    • Author(s)
      Kikuta Kazutaka、Nakayama Robert、Yamaguchi Sayaka、Nishiwaki Yuuji、Susa Michiro、Nishimoto Kazumasa、Horiuchi Keisuke、Nakamura Masaya、Matsumoto Morio、Morioka Hideo
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 48 Issue: 2 Pages: 130-134

    • DOI

      10.1093/jjco/hyx184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10874, KAKENHI-PROJECT-16H02676
  • [Journal Article] Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma.2016

    • Author(s)
      Nakayama R, Zhang YX, Czaplinski JT, Anatone AJ, Sicinska ET, Fletcher JA, Demetri GD, Wagner AJ
    • Journal Title

      Oncotarget

      Volume: Mar 29;7(13) Issue: 13 Pages: 16581-92

    • DOI

      10.18632/oncotarget.7667

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02676
  • [Journal Article] Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma.2016

    • Author(s)
      Morioka H, Takahashi S, Araki N, Sugiura H, Ueda T, Takahashi M, Yonemoto T, Hiraga H, Hiruma T, Kunisada T, Matsumine A, Susa M, Nakayama R, Nishimoto K, Kikuta K, Horiuchi K, Kawai A
    • Journal Title

      BMC Cancer

      Volume: 16 Issue: 1 Pages: 479-479

    • DOI

      10.1186/s12885-016-2511-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-15K20017, KAKENHI-PROJECT-16K10862, KAKENHI-PROJECT-16K10874
  • [Journal Article] Forty-eight cases of leiomyosarcoma of bone in Japan: A multicenter study from the Japanese musculoskeletal oncology group.2016

    • Author(s)
      Mori T, Nakayama R, Endo M, Hiraga H, Tomita M, Fukase N, Kobayashi E, Kawai A, Ueda T, Morioka H.
    • Journal Title

      J Surg Oncol

      Volume: Sep;114(4) Issue: 4 Pages: 495-500

    • DOI

      10.1002/jso.24322

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26713046
  • [Journal Article] Metastatic Patterns of Myxoid/Round Cell Liposarcoma : A Review of a 25-Year Experience2012

    • Author(s)
      N Asano, M Susa, S Hosaka, R Nakayama, et al
    • Journal Title

      Sarcoma

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791413
  • [Journal Article] Metastatic Patterns of Myxoid/Round Cell Liposarcoma : A Review of a25-Year Experience Sarcoma2012

    • Author(s)
      N Asano, M Susa, S Hosaka, R Nakayama, et al
    • Volume
      (in press)
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791413
  • [Presentation] 全エクソン遺伝子解析を用いた骨軟部腫瘍の臨床的ゲノム解析.2023

    • Author(s)
      中山ロバートほか
    • Organizer
      第96回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] 希少な進行期悪性骨・軟部腫瘍を対象とした医師主導治験の課題.2023

    • Author(s)
      中山ロバートほか
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] 骨・軟部腫瘍のゲノム解析 -全エクソン解析は 遺伝子パネル解析と比較して有用か-.2023

    • Author(s)
      中山ロバートほか
    • Organizer
      第56回日本整形外科学会骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] がん遺伝子パネル検査PleSSision-Rapidを用いた骨・軟部腫瘍のゲノム解析.2022

    • Author(s)
      1.中山ロバート
    • Organizer
      第95回日本整形外科学会学術総会.
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] PleSSision-Rapid を用いた骨・軟部腫瘍のがん遺伝子パネル検査.2022

    • Author(s)
      2.中山ロバート
    • Organizer
      第55回 日本整形外科学会骨・軟部腫瘍学術集会.
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] 治療への応用からみた悪性骨軟部腫瘍の分子病理2021

    • Author(s)
      中山ロバート
    • Organizer
      第18回 日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09257
  • [Presentation] 巨細胞性骨腫瘍における変異H3に対する免疫組織染色の役割.2019

    • Author(s)
      29中山ロバート,馬場喜博,齊藤誠人,中川瑠美,弘實透,山口さやか,浅野尚文,大喜多肇,中村雅也,松本守雄
    • Organizer
      第52回 日本整形外科学会骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] 慶應義塾大学病院における骨・軟部腫瘍に対する遺伝子診断の現状と今後の展望.2019

    • Author(s)
      中山ロバート,加藤容崇,中川瑠美,弘實透,山口さやか,浅野尚文,四十物絵理子,西原広史,中村雅也,松本守雄.
    • Organizer
      第52回 日本整形外科学会骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SMARCB1はSWI/SNF複合体によるエンハンサー活性化に必須である2018

    • Author(s)
      中山ロバート,Cigall Kadoch,George D. Demetri,松本守雄,中村雅也
    • Organizer
      第91回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] 腫瘍抑制遺伝子SMARCB1の導入によるSWI/SNF複合体を介したエンハンサーおよびバイバレント領域のプロモーターの活性化.2018

    • Author(s)
      中山ロバート,John L.Pulice,Cigall Kadoch,松本守雄,中村雅也.
    • Organizer
      第33回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] Genome-wide mistargeting of oncogenic SWI/SNF complexes in SMARCB1-deficient cancers.2018

    • Author(s)
      Nakayama R,Pulice J,Valencia A,Kadoch C,Matsumoto M,Nakamura M.
    • Organizer
      第77回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SMARCB1(BAF47)欠損腫瘍における発がん性SWI/SNF(BAF)複合体のプロテオーム解析2017

    • Author(s)
      中山ロバート,Cigall Kadoch,George D. Demetri,森岡秀夫,中村雅也,松本守雄.
    • Organizer
      第76回日本癌学会学術総会,横浜
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SMARCB1欠損腫瘍における発がん性SW/SNF複合体の異常な遺伝子発現制御.2017

    • Author(s)
      中山ロバート,Cigall Kadoch,George D.Demetri,中村雅也,松本守雄,森岡秀夫
    • Organizer
      第90回日本整形外科学会学術総会,仙台
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SMARCB1(BAF47)欠損腫瘍における発がん性SWI/SNF(BAF)複合体のプロテオーム解析2017

    • Author(s)
      中山ロバート
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-16H02676
  • [Presentation] SMARCB1の欠損はSW1/SNF複合体のクロマチンへの結合を不安定化させる.2017

    • Author(s)
      中山ロバート,Cigall Kadoch,George D.Demetri,中村雅也,松本守雄,森岡秀夫.
    • Organizer
      第50回日本整形外科学会骨・軟部腫瘍学術集会,東京
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SSX drives gain-of-function BAF complex chromatin affinity and genomic targeting in synovial sarcoma.2017

    • Author(s)
      McBride M,Nakayama R,Pulice J,Mashtalir N,Ingram D,Shern J,Khan J,Hornic J,Lazar A,Kadoch C
    • Organizer
      American Association for Cancer Research (AACR), Washington D.C., USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10985
  • [Presentation] SMARCB1の欠損はSW1/SNF複合体のクロマチンへの結合を不安定化させる2017

    • Author(s)
      中山ロバート
    • Organizer
      日本整形外科学会骨・軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-16H02676
  • [Presentation] 再発粘液線維肉腫の治療成績2013

    • Author(s)
      中山ロバート, 菊田一貴, 須佐美知郎, 渡部逸 央, 堀内圭輔, 鈴木禎寿, 穴澤卯圭, 矢部啓夫, 戸山芳昭, 森岡秀夫
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-24701010
  • [Presentation] Clinical Outcome of Recurrent Myxofibrosarcoma2013

    • Author(s)
      Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanab, Eisuke Kobayashi, Fumihiko Nakatani, Akira Kawai, Hirokazu Chuman, Yoshiaki Toyama, Hideo Morioka
    • Organizer
      26th annual meeting of European Musculoskeletal Oncology Society
    • Place of Presentation
      Gothenburg, Sweden
    • Data Source
      KAKENHI-PROJECT-24701010
  • [Presentation] Clinical Outcome of Recurrent Myxofibrosarcoma2012

    • Author(s)
      Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanabe, Keisuke Horiuchi, Yoshihisa Suzuki, Ukei Anazawa, Hiroo Yabe, Yoshiaki Toyama, Hideo Morioka
    • Organizer
      9th Asia Pacific Musculoskeletal Tumour Society Meeting
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Data Source
      KAKENHI-PROJECT-24701010
  • [Presentation] 粘液線維肉腫の治療成績2012

    • Author(s)
      中山ロバート, 菊田一貴, 須佐美知郎, 渡部逸央, 堀内圭輔, 鈴木禎寿, 穴澤卯圭, 矢部啓夫, 戸山芳昭, 森岡秀夫
    • Organizer
      第45回日本整形外科学会骨・軟部腫瘍学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24701010
  • [Presentation] Clinical Outcome of Myxofibrosarcoma2012

    • Author(s)
      Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanabe, Keisuke Horiuchi, Yoshihisa Suzuki, Ukei Anazawa, Hiroo Yabe, Yoshiaki Toyama, Hideo Morioka
    • Organizer
      25th annual meeting of European Musculoskeletal Oncology Society
    • Place of Presentation
      Bologna, Italy
    • Data Source
      KAKENHI-PROJECT-24701010
  • 1.  Matsuda Koichi (90401257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  中村 卓郎 (00180373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  竹中 聡 (00588379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  高阪 真路 (00627119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  松本 嘉寛 (10346794)
    # of Collaborated Projects: 1 results
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  • 6.  植田 幸嗣 (10509110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  穴澤 卯圭 (20245525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  比留間 徹 (20254188)
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  • 24.  平田 真 (50401071)
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  • 25.  米本 司 (50506318)
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  • 28.  末原 義之 (70509405)
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  • 29.  國定 俊之 (80346428)
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  • 30.  山田 聡 (80405208)
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  • 38.  吉川 秀樹 (60191558)
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  • 47.  江森 誠人
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  • 48.  国定 俊之
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  • 49.  田仲 和宏
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