Nakayama TurrentRobert 中山タラントロバート

… Alternative Names

Nakayama Robert 中山タラントロバート

NAKAYAMA Robert t. 中山タラントロバート

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Researcher Number	00365298
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 講師 2017 – 2023: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部(信濃町), 助教 2009 – 2013: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Tumor diagnosis Except Principal Investigator Basic Section 50010:Tumor biology-related / Orthopaedic surgery
Keywords	Principal Investigator 肉腫 / 悪性軟部腫瘍 / 骨軟部腫瘍 / 遺伝子 / 癌 / cfDNA / リキッドバイオプシー / トランスレーショナルリサーチ / 遺伝子発現制御 / SS18-SSX … More / クロマチンリモデリング複合体 / BAF / SWI/SNF / AYA世代 / 希少がん / 滑膜肉腫 / SWI/SNF複合体 / 融合遺伝子 / トランスレーショナル・リサーチ / ゲノム / 発がん / がん発現解析 / APAM17 / CD44 / 発現解析 / ADAM17 / CD4 / 転移 / 蛋白質 / シグナル伝達 … More Except Principal Investigator 悪性末梢神経鞘腫 / 神経線維腫 / 神経鞘腫 / 腫瘍オルガノイド培養 / 骨軟部肉腫 / 整形外科 / ゲノム / 癌 / 融合遺伝子 / 骨軟部腫瘍 / がんゲノム / ゲノム解析 / 肉腫 Less

軟骨系腫瘍オルガノイドを用いた軟骨肉腫腫瘍化の分子機構解明と新規薬物治療開発Principal Investigator
- Principal Investigator
  
  中山タラントロバート
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Keio University
末梢神経腫瘍オルガノイドを用いた腫瘍化の分子機構解明と新規薬物治療開発
- Principal Investigator
  
  森智章
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
リキッドバイオプシーによる骨軟部腫瘍の病勢モニタリングの実用化を目指した研究Principal Investigator
- Principal Investigator
  
  中山タラントロバート
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Keio University
Oncogenic role of aberrant SWI/SNF chromatin remodeling complex in synovial sarcomaPrincipal Investigator
- Principal Investigator
  
  Nakayama Robert
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma
- Principal Investigator
  
  Matsuda Koichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
粘液線維肉腫の診断・予後関連バイオマーカーの開発Principal Investigator
- Principal Investigator
  
  中山タラントロバート
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Keio University
Expression and functional analysis of CD44 and ADAM17in bone and soft tissue tumorsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Robert t.
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University

All 2023 2022 2021 2019 2018 2017 2016 2013 2012

All Journal Article Presentation

[Journal Article] がん遺伝子パネル検査を用いた骨軟部腫瘍のゲノム解析2023
- Author(s)
  山口さやか, 中山ロバート
- Journal Title
  
  癌と化学療法
  
  Volume: 50巻3号 Pages: 309-313
- Data Source
  KAKENHI-PROJECT-21K09257
[Journal Article] 骨肉腫ゲノムの多様性2021
- Author(s)
  齊藤誠人，関田哲也，山口さやか，中山ロバート
- Journal Title
  
  別冊整形外科
  
  Volume: 79
- Data Source
  KAKENHI-PROJECT-21K09257
[Journal Article] Pseudomyogenic hemangioendothelioma of bone treated with denosumab: a case report2019
- Author(s)
  Otani Shinya、Nakayama Robert、Sekita Tetsuya、Hirozane Toru、Asano Naofumi、Nishimoto Kazumasa、Sasaki Aya、Okita Hajime、Morioka Hideo、Nakamura Masaya、Matsumoto Morio
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 872-872
- DOI
  10.1186/s12885-019-6072-8
- Open Access
- Data Source
  KAKENHI-PROJECT-19K09637, KAKENHI-PROJECT-17K10985
[Journal Article] Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG03042019
- Author(s)
  Tanaka Kazuhiro、Mizusawa Junki、Naka Norifumi、Kawai Akira、et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 1-7
- DOI
  10.1186/s12885-019-6114-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-17K10985
[Journal Article] The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma2018
- Author(s)
  McBride Matthew J.、Pulice John L.、Beird Hannah C.、Ingram Davis R.、D’Avino Andrew R.、Shern Jack F.、Charville Gregory W.、Hornick Jason L.、Nakayama Robert T. et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 33 Issue: 6 Pages: 1128-1141.e7
- DOI
  10.1016/j.ccell.2018.05.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10985
[Journal Article] Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG03042018
- Author(s)
  Tanaka K, Ogawa G, Mizusawa J, Naka N, Kawai A, Takahashi M, Hiruma T, Matsumoto Y, Tsuchiya H, Nakayama R, Hatano H, Emori M, Hosaka M, Yoshida Y, Toguchida J, Abe S, Asanuma K, Yokoyama R, Hiraga H, Yonemoto T, Morii T, Matsumoto S, Nagano A, Yoshikawa H, Fukuda H, Ozaki T, Iwamoto Y.
- Journal Title
  
  World Journal of Surgical Oncology
  
  Volume: 16 Issue: 1 Pages: 160-160
- DOI
  10.1186/s12957-018-1462-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10974, KAKENHI-PROJECT-17K10985, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-17K19725
[Journal Article] A histological positive margin after surgery is correlated with high local re-recurrence rate in patients with recurrent myxofibrosarcoma2017
- Author(s)
  Kikuta K, Nakayama R, Yoshida A, Sasaki A, Kameyama K, Chuman H, Kawai A, Nakamura M, Matsumoto M, Morioka H
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 47 (4) Issue: 4 Pages: 334-341
- DOI
  10.1093/jjco/hyw199
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20017, KAKENHI-PROJECT-16H02676
[Journal Article] SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters2017
- Author(s)
  Nakayama Robert T、Pulice John L、Valencia Alfredo M、McBride Matthew J、McKenzie Zachary M、Gillespie Mark A、Ku Wai Lim、Teng Mingxiang、Cui Kairong、Williams Robert T、Cassel Seth H、Qing He、Widmer Christian J、Demetri George D、Irizarry Rafael A、Zhao Keji、Ranish Jeffrey A、Kadoch Cigall
- Journal Title
  
  Nature Genetics
  
  Volume: 49 Issue: 11 Pages: 1613-1623
- DOI
  10.1038/ng.3958
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10985, KAKENHI-PROJECT-16H02676
[Journal Article] Wide-spread ignorance on the treatment of subcutaneous malignant tumors; a questionnaire-based study2017
- Author(s)
  Kikuta Kazutaka、Nakayama Robert、Yamaguchi Sayaka、Nishiwaki Yuuji、Susa Michiro、Nishimoto Kazumasa、Horiuchi Keisuke、Nakamura Masaya、Matsumoto Morio、Morioka Hideo
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 48 Issue: 2 Pages: 130-134
- DOI
  10.1093/jjco/hyx184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10874, KAKENHI-PROJECT-16H02676
[Journal Article] Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma.2016
- Author(s)
  Nakayama R, Zhang YX, Czaplinski JT, Anatone AJ, Sicinska ET, Fletcher JA, Demetri GD, Wagner AJ
- Journal Title
  
  Oncotarget
  
  Volume: Mar 29;7(13) Issue: 13 Pages: 16581-92
- DOI
  10.18632/oncotarget.7667
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02676
[Journal Article] Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma.2016
- Author(s)
  Morioka H, Takahashi S, Araki N, Sugiura H, Ueda T, Takahashi M, Yonemoto T, Hiraga H, Hiruma T, Kunisada T, Matsumine A, Susa M, Nakayama R, Nishimoto K, Kikuta K, Horiuchi K, Kawai A
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Issue: 1 Pages: 479-479
- DOI
  10.1186/s12885-016-2511-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-15K20017, KAKENHI-PROJECT-16K10862, KAKENHI-PROJECT-16K10874
[Journal Article] Forty-eight cases of leiomyosarcoma of bone in Japan: A multicenter study from the Japanese musculoskeletal oncology group.2016
- Author(s)
  Mori T, Nakayama R, Endo M, Hiraga H, Tomita M, Fukase N, Kobayashi E, Kawai A, Ueda T, Morioka H.
- Journal Title
  
  J Surg Oncol
  
  Volume: Sep;114(4) Issue: 4 Pages: 495-500
- DOI
  10.1002/jso.24322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26713046
[Journal Article] Metastatic Patterns of Myxoid/Round Cell Liposarcoma : A Review of a 25-Year Experience2012
- Author(s)
  N Asano, M Susa, S Hosaka, R Nakayama, et al
- Journal Title
  
  Sarcoma
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791413
[Journal Article] Metastatic Patterns of Myxoid/Round Cell Liposarcoma : A Review of a25-Year Experience Sarcoma2012
- Author(s)
  N Asano, M Susa, S Hosaka, R Nakayama, et al
- Volume
  (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791413
[Presentation] 全エクソン遺伝子解析を用いた骨軟部腫瘍の臨床的ゲノム解析.2023
- Author(s)
  中山ロバートほか
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] 希少な進行期悪性骨・軟部腫瘍を対象とした医師主導治験の課題.2023
- Author(s)
  中山ロバートほか
- Organizer
  第38回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] 骨・軟部腫瘍のゲノム解析 -全エクソン解析は遺伝子パネル解析と比較して有用か-.2023
- Author(s)
  中山ロバートほか
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] がん遺伝子パネル検査PleSSision-Rapidを用いた骨・軟部腫瘍のゲノム解析．2022
- Author(s)
  1.中山ロバート
- Organizer
  第95回日本整形外科学会学術総会．
- Invited
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] PleSSision-Rapid を用いた骨・軟部腫瘍のがん遺伝子パネル検査．2022
- Author(s)
  2.中山ロバート
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会．
- Invited
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] 治療への応用からみた悪性骨軟部腫瘍の分子病理2021
- Author(s)
  中山ロバート
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09257
[Presentation] 巨細胞性骨腫瘍における変異H3に対する免疫組織染色の役割．2019
- Author(s)
  29中山ロバート，馬場喜博，齊藤誠人，中川瑠美，弘實透，山口さやか，浅野尚文，大喜多肇，中村雅也，松本守雄
- Organizer
  第52回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] 慶應義塾大学病院における骨・軟部腫瘍に対する遺伝子診断の現状と今後の展望．2019
- Author(s)
  中山ロバート，加藤容崇，中川瑠美，弘實透，山口さやか，浅野尚文，四十物絵理子，西原広史，中村雅也，松本守雄．
- Organizer
  第52回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SMARCB1はSWI/SNF複合体によるエンハンサー活性化に必須である2018
- Author(s)
  中山ロバート，Cigall Kadoch，George D. Demetri，松本守雄，中村雅也
- Organizer
  第91回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] 腫瘍抑制遺伝子SMARCB1の導入によるSWI/SNF複合体を介したエンハンサーおよびバイバレント領域のプロモーターの活性化．2018
- Author(s)
  中山ロバート，John L.Pulice，Cigall Kadoch，松本守雄，中村雅也．
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] Genome-wide mistargeting of oncogenic SWI/SNF complexes in SMARCB1-deficient cancers．2018
- Author(s)
  Nakayama R，Pulice J，Valencia A，Kadoch C，Matsumoto M，Nakamura M．
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SMARCB1(BAF47)欠損腫瘍における発がん性SWI/SNF(BAF)複合体のプロテオーム解析2017
- Author(s)
  中山ロバート，Cigall Kadoch，George D. Demetri，森岡秀夫，中村雅也，松本守雄．
- Organizer
  第76回日本癌学会学術総会，横浜
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SMARCB1欠損腫瘍における発がん性SW/SNF複合体の異常な遺伝子発現制御．2017
- Author(s)
  中山ロバート，Cigall Kadoch，George D.Demetri，中村雅也，松本守雄，森岡秀夫
- Organizer
  第90回日本整形外科学会学術総会，仙台
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SMARCB1(BAF47)欠損腫瘍における発がん性SWI/SNF(BAF)複合体のプロテオーム解析2017
- Author(s)
  中山ロバート
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-16H02676
[Presentation] SMARCB1の欠損はSW1/SNF複合体のクロマチンへの結合を不安定化させる．2017
- Author(s)
  中山ロバート，Cigall Kadoch，George D.Demetri，中村雅也，松本守雄，森岡秀夫．
- Organizer
  第50回日本整形外科学会骨・軟部腫瘍学術集会，東京
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SSX drives gain-of-function BAF complex chromatin affinity and genomic targeting in synovial sarcoma．2017
- Author(s)
  McBride M，Nakayama R，Pulice J，Mashtalir N，Ingram D，Shern J，Khan J，Hornic J，Lazar A，Kadoch C
- Organizer
  American Association for Cancer Research (AACR), Washington D.C., USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10985
[Presentation] SMARCB1の欠損はSW1/SNF複合体のクロマチンへの結合を不安定化させる2017
- Author(s)
  中山ロバート
- Organizer
  日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-16H02676
[Presentation] 再発粘液線維肉腫の治療成績2013
- Author(s)
  中山ロバート, 菊田一貴, 須佐美知郎, 渡部逸央, 堀内圭輔, 鈴木禎寿, 穴澤卯圭, 矢部啓夫, 戸山芳昭, 森岡秀夫
- Organizer
  第86回日本整形外科学会学術総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24701010
[Presentation] Clinical Outcome of Recurrent Myxofibrosarcoma2013
- Author(s)
  Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanab, Eisuke Kobayashi, Fumihiko Nakatani, Akira Kawai, Hirokazu Chuman, Yoshiaki Toyama, Hideo Morioka
- Organizer
  26th annual meeting of European Musculoskeletal Oncology Society
- Place of Presentation
  Gothenburg, Sweden
- Data Source
  KAKENHI-PROJECT-24701010
[Presentation] Clinical Outcome of Recurrent Myxofibrosarcoma2012
- Author(s)
  Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanabe, Keisuke Horiuchi, Yoshihisa Suzuki, Ukei Anazawa, Hiroo Yabe, Yoshiaki Toyama, Hideo Morioka
- Organizer
  9th Asia Pacific Musculoskeletal Tumour Society Meeting
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-24701010
[Presentation] 粘液線維肉腫の治療成績2012
- Author(s)
  中山ロバート, 菊田一貴, 須佐美知郎, 渡部逸央, 堀内圭輔, 鈴木禎寿, 穴澤卯圭, 矢部啓夫, 戸山芳昭, 森岡秀夫
- Organizer
  第45回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24701010
[Presentation] Clinical Outcome of Myxofibrosarcoma2012
- Author(s)
  Robert Nakayama, Kazutaka Kikuta, Michiro Susa, Itsuo Watanabe, Keisuke Horiuchi, Yoshihisa Suzuki, Ukei Anazawa, Hiroo Yabe, Yoshiaki Toyama, Hideo Morioka
- Organizer
  25th annual meeting of European Musculoskeletal Oncology Society
- Place of Presentation
  Bologna, Italy
- Data Source
  KAKENHI-PROJECT-24701010

1. Matsuda Koichi (90401257)

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Nakayama TurrentRobert 中山 タラントロバート

Nakayama Robert 中山 タラントロバート

NAKAYAMA Robert t. 中山 タラントロバート

Research Projects

Research Products

Co-Researchers

軟骨系腫瘍オルガノイドを用いた軟骨肉腫腫瘍化の分子機構解明と新規薬物治療開発Principal Investigator

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末梢神経腫瘍オルガノイドを用いた腫瘍化の分子機構解明と新規薬物治療開発

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リキッドバイオプシーによる骨軟部腫瘍の病勢モニタリングの実用化を目指した研究Principal Investigator

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Oncogenic role of aberrant SWI/SNF chromatin remodeling complex in synovial sarcomaPrincipal Investigator

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Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma

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粘液線維肉腫の診断・予後関連バイオマーカーの開発Principal Investigator

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Expression and functional analysis of CD44 and ADAM17in bone and soft tissue tumorsPrincipal Investigator

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[Journal Article] がん遺伝子パネル検査を用いた骨軟部腫瘍のゲノム解析2023

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[Journal Article] 骨肉腫ゲノムの多様性2021

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[Journal Article] Pseudomyogenic hemangioendothelioma of bone treated with denosumab: a case report2019

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[Journal Article] Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG03042019

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[Journal Article] The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma2018

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[Journal Article] Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG03042018

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[Journal Article] A histological positive margin after surgery is correlated with high local re-recurrence rate in patients with recurrent myxofibrosarcoma2017

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Nakayama TurrentRobert 中山タラントロバート

Nakayama Robert 中山タラントロバート

NAKAYAMA Robert t. 中山タラントロバート

[Presentation] 骨・軟部腫瘍のゲノム解析 -全エクソン解析は遺伝子パネル解析と比較して有用か-.2023