Nakayama Takahiro 中山隆宏

… Alternative Names

Takahiro Nakayama 中山隆宏

NAKAYAMA Takahiro 中山隆宏

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Researcher Number	00532821
Other IDs
Affiliation (Current)	2025: 金沢大学, ナノ生命科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢大学, ナノ生命科学研究所, 准教授 2017 – 2020: 金沢大学, ナノ生命科学研究所, 准教授 2017: 金沢大学, バイオAFM先端研究センター, 准教授 2016: 金沢大学, バイオAFM先端研究センター, 助教 2014: 金沢大学, バイオAFM先端研究センター, 助教 2013: 金沢大学, 学内共同利用施設等, 助教 2012 – 2013: 金沢大学, バイオＡＦＭ先端研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Biophysics / Transformative Research Areas, Section (III) / Chemical biology Except Principal Investigator Neurology / Transformative Research Areas, Section (III) / Complex systems
Keywords	Principal Investigator 原子間力顕微鏡 / 一分子観察 / 分子イメージング / アミロイド / がん抑制因子p53 / 凝集 / 脳・神経 / 生体分子 / 走査プローブ顕微鏡 / 生物物理 … More / 高速原子間力顕微鏡 / 分子シャペロン / Hsp104立体構造動態のヌクレオチド依存性 / アミロイド線維立体構造 / 高速原子間力顕微鏡ビルトイン用インキュベータ / アミロイドタンパク / がん / プリオン / タンパク凝集 / がん抑制因子 / 高速原子間力顕微鏡（高速AFM） / コラゲナーゼ / コラーゲン / １分子観察 / 酵素反応の化学力学共役 … More Except Principal Investigator アミロイドβ蛋白 / アルツハイマー病 / 女性活躍 / 国際共同研究 / アウトリーチ / 若手支援 / 研究推進 / タンパク質 / ダイナミクス / バイオイメージング / 蛋白質 / 走査型プローブ顕微鏡 / 高速AFM / アミロイドβタンパク / γ線照射 / オートクレーブ処理 / 凝集 / 防御 / 伝播 / 高速原子間力顕微鏡 Less

Universalization of high-speed atomic force microscopy targetsPrincipal Investigator
- Principal Investigator
  
  中山隆宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa University
Investigation of relationship between structural variety and function of tumor suppressor protein, p53Principal Investigator
- Principal Investigator
  
  中山隆宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kanazawa University
Supramolecular behavior and dynamic capture of meta-aggregates
- Principal Investigator
  
  村上一馬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Structural dynamics of tumor suppressor protein, p53, in its aggregation processPrincipal Investigator
- Principal Investigator
  
  Takahiro Nakayama
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kanazawa University
Study on transmission of Abeta aggregates and its prevention
- Principal Investigator
  
  Yamada Masahito
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Video-imaging of amyloid disaggregase, Hsp104, on amyloid fibrilsPrincipal Investigator
- Principal Investigator
  
  Nakayama Takahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kanazawa University
The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopy
- Principal Investigator
  
  Ono Kenjiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
  Kanazawa University
Development of advanced high-speed AFM and analysis of proteins' action mechanism
- Principal Investigator
  
  Ando Toshio
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kanazawa University
Video imaging by high speed atomic force microscopy of collagenase movement on collagen fibrilsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Takahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kanazawa University
アクチンストレスファイバーの力学応答に伴う構造変化の高速AFM観察Principal Investigator
- Principal Investigator
  
  中山隆宏
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biophysics
- Research Institution
  Kanazawa University

All 2023 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and antagonist for amylin fibrillation2019
- Author(s)
  B. R. Sahoo, T. Genjo, T. Watanabe-Nakayama, A. K. Stoddard, T. Ando, K. Yasuhara, C. A. Fierke, A. Ramamoorthy
- Journal Title
  
  Chem. Sci.
  
  Volume: 10 Issue: 14 Pages: 3976-3986
- DOI
  10.1039/c8sc05771k
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-17K19353, KAKENHI-PROJECT-17H06121
[Journal Article] Visualization of Protein Assembly Dynamics by Using High-speed Atomic Force Microscopy2018
- Author(s)
  中山隆宏、紺野宏記、山田正仁、小野賢二郎
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 58 Issue: 2 Pages: 086-088
- DOI
  10.2142/biophys.58.086
- NAID
  130006594328
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-16K18524
[Journal Article] High-Speed Atomic Force Microscopy Reveals Loss of Nuclear Pore Resilience as a Dying Code in Colorectal Cancer Cells.2017
- Author(s)
  Mohamed MS, Kobayashi A, Taoka A, Watanabe-Nakayama T, Kikuchi Y, Hazawa M, Minamoto T, Fukumori Y, Kodera N, Uchihashi T, Ando T, Wong RW
- Journal Title
  
  ACS Nano.
  
  Volume: 11(6) Issue: 6 Pages: 5567-5578
- DOI
  10.1021/acsnano.7b00906
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-17K19345, KAKENHI-PROJECT-17K16332, KAKENHI-PUBLICLY-17H05874, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-15H04360
[Journal Article] High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.2016
- Author(s)
  Watanabe-Nakayama T*, Ono K*, Itami M, Takahashi R, Teplow DB, Yamada M. *Equally contributed.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113 Issue: 21 Pages: 5835-5840
- DOI
  10.1073/pnas.1524807113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils2016
- Author(s)
  T. Watanabe-Nakayama, M. Itami, N. Kodera, T. Ando, H. Konno,
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 28975-28975
- DOI
  10.1038/srep28975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01177, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-24227005, KAKENHI-PROJECT-15H04360
[Journal Article] Requirement of LIM domains for the transient accumulation of paxillin at damaged stress fibres2013
- Author(s)
  Takahiro Watanabe-Nakayama
- Journal Title
  
  Biology open
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24870011
[Presentation] 多様なアミロイド凝集体による神経変性メカニズムの解明（シンポジウム企画）2023
- Author(s)
  村上一馬、小野賢二郎、矢吹悌、中山隆宏
- Organizer
  第64回日本神経病理学会総会学術研究会／第66回日本神経化学会大会合同大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03849
[Presentation] Nano-Space Video Imaging Reveals Structural Dynamics of FibrousProtein Assembly and Relevant Enzymes2017
- Author(s)
  Takahiro Watanabe-Nakayama, Noriyuki Kodera, Hiroki Konno, Kenjiro Ono, David B. Teplow, Masahito Yamada, Toshio Ando
- Organizer
  Biophysical Society | 61 st Annual Meeting
- Place of Presentation
  ニューオリンズ（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18524
[Presentation] Nanometer resolution video imaging reveals structural dynamics of single amyloidogenic protein assemblies2017
- Author(s)
  Takahiro Watanabe-Nakayama
- Organizer
  The 5th Asia Pacific Protein Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18524
[Presentation] 高速原子力間顕微鏡を用いたAβ42凝集過程の観察2016
- Author(s)
  小野賢二郎、中山隆宏、伊丹将大、高橋良一、David Teplow、山田正仁
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Positioning of early aggregates of Aβ in its aggregation process2015
- Author(s)
  小野　賢二郎、中山　隆宏、山田　正仁
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Real time imaging of collagenase behavior by high speed atomic force microscopy2014
- Author(s)
  Takahiro Nakayama, Noriyuki Kodera, Hiroki Kon'no, Toshio Ando
- Organizer
  日本生物物理学会
- Place of Presentation
  札幌市
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25870262
[Presentation] High-speed AFM observation of collagenolysis by collagenases
- Author(s)
  中山隆宏、古寺哲幸、紺野宏記、安藤敏夫
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25870262

1. Ono Kenjiro (70377381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. YAMADA Masahito (80191336)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. Ando Toshio (50184320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. UCHIHASHI Takayuki (30326300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KONNO Hiroki (80419267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. WATANABE Shinji (70455864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 濱口毅 (70452109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂井健二 (00572306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 池田篤平 (30755773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村上一馬 (80571281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 矢吹悌 (70756121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 渡邉信嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. WONG W・R

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakayama Takahiro 中山 隆宏

Takahiro Nakayama 中山 隆宏

NAKAYAMA Takahiro 中山 隆宏

Research Projects

Research Products

Co-Researchers

Universalization of high-speed atomic force microscopy targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of relationship between structural variety and function of tumor suppressor protein, p53Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Supramolecular behavior and dynamic capture of meta-aggregates

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural dynamics of tumor suppressor protein, p53, in its aggregation processPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on transmission of Abeta aggregates and its prevention

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Video-imaging of amyloid disaggregase, Hsp104, on amyloid fibrilsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of advanced high-speed AFM and analysis of proteins' action mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Video imaging by high speed atomic force microscopy of collagenase movement on collagen fibrilsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アクチンストレスファイバーの力学応答に伴う構造変化の高速AFM観察Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and antagonist for amylin fibrillation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visualization of Protein Assembly Dynamics by Using High-speed Atomic Force Microscopy2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] High-Speed Atomic Force Microscopy Reveals Loss of Nuclear Pore Resilience as a Dying Code in Colorectal Cancer Cells.2017

Nakayama Takahiro 中山隆宏

Takahiro Nakayama 中山隆宏

NAKAYAMA Takahiro 中山隆宏