Okai Masahiko 岡井公彦

… Alternative Names

OKAI MASAHIKO 岡井公彦

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Researcher Number	00596562
Other IDs
Affiliation (Current)	2025: 東京海洋大学, 学術研究院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京海洋大学, 学術研究院, 准教授 2016 – 2019: 東京海洋大学, 学術研究院, 助教 2015: 東京海洋大学, 大学院海洋科学技術研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 40040:Aquatic life science-related / Applied biochemistry Except Principal Investigator Aquatic life science / Basic Section 63010:Environmental dynamic analysis-related / Basic Section 40040:Aquatic life science-related / Applied microbiology
Keywords	Principal Investigator 立体構造解析 / 立体構造 / 抗菌作用 / 抗菌ペプチド / サンゴ / バイオテクノロジー / 酵素 / 基質改変 / 構造解析 / 環境浄化 / 結晶構造解析 / 酸素添加酵素 … More Except Principal Investigator … More 微生物 / 酵素 / 劣化度 / 日本沿岸 / カルボニルインデックス / 時空間動態 / 劣化 / マイクロプラスチック / 生体防御 / 機能性タンパク質 / テトロドトキシン / 生体分子 / 水産学 / 高分子構造・物性 / 蛋白質 / 深海環境 / 遺伝子発現効率 / 組換え体 / 結晶構造解析 / 高効率発現 / 構造と性質 / 好圧性 / Moritella属 / 遺伝子分布 / バイオサーファクタント / 耐圧菌 / 好冷菌 / 水素結合 / 遺伝子対 / 未知遺伝子 / 海洋中層 / プロテアーゼ / リパーゼ / 高圧適応 / バイオテクノロジー / 遺伝子 / 環境 / 生態系 / 中和能 / 中和活性 / 中性圏 / 強酸性水圏 / アミノ酸代謝 / バイオリアクター / 広域pH耐性酵母 / アルカリ化酵母 / 塩基性水圏 / 中性水圏 / 酸性水圏 / 分子機構 / pH耐性 / 中和 / 強酸性水 / 酵母 / 進化 / ゲノム / 可動性遺伝因子 / 環境汚染物質 / スフィンゴモナス Less

Spatio-temporal dynamics of deterioration of marine microplastics
- Principal Investigator
  
  荒川久幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63010:Environmental dynamic analysis-related
- Research Institution
  Tokyo University of Marine Science and Technology
Elucidation of structure-function relationship of antimicrobial peptides from the coral Acropora digitiferaPrincipal Investigator
- Principal Investigator
  
  OKAI Masahiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Tokyo University of Marine Science and Technology
Structure and function of pufferfish toxin, tetrodotoxin, binding proteins as biological defense agent
- Principal Investigator
  
  Nagashima Yuji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Niigata Agro-Food University
Molecular mechanism of neutralization of acid envirnments by alkalinization yeasts and their enzymes
- Principal Investigator
  
  Urano Naoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic life science
- Research Institution
  Tokyo University of Marine Science and Technology
Structural feature of nobel piezophilic lipases from marine piezophilic psychrophile
- Principal Investigator
  
  Ishida Masami
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic life science
- Research Institution
  Tokyo University of Marine Science and Technology
Construction of initial degradation system of DDT using enzymes with modified substrate specificityPrincipal Investigator
- Principal Investigator
  
  Okai Masahiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tokyo University of Marine Science and Technology
Mechanisms for acquiring ability to degrade novel compounds in sphingomonads and their applications
- Principal Investigator
  
  Nagata Yuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2018 2017 2016 2013

All Journal Article Presentation

[Journal Article] Heterologous expression and functional characterization of cysteamine dioxygenase from the deep-sea mussel Bathymodiolus septemdierum2023
- Author(s)
  Yoda Kotaro、Takagi Toshiyuki、Koito Tomoko、Okai Masahiko、Makita Hiroko、Mitsunobu Satoshi、Yoshida Takao、Inoue Koji
- Journal Title
  
  Fisheries Science
  
  Volume: 89 Issue: 3 Pages: 387-397
- DOI
  10.1007/s12562-023-01674-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06779, KAKENHI-PROJECT-21K05768
[Journal Article] Primary Structure and Conformation of a Tetrodotoxin-Binding Protein in the Hemolymph of Non-Toxic Shore Crab Hemigrapsus sanguineus2023
- Author(s)
  Nagashima Yuji、Fujimoto Kenta、Okai Masahiko、Kitani Yoichiro、Yoshinaga-Kiriake Aya、Ishizaki Shoichiro
- Journal Title
  
  Journal of Marine Science and Engineering
  
  Volume: 11 Issue: 1 Pages: 181-181
- DOI
  10.3390/jmse11010181
- Data Source
  KAKENHI-PROJECT-21K05768
[Journal Article] Q301P mutant of Vibrio PR protease affects activities under low-temperature and high-pressure conditions2020
- Author(s)
  Masahiko Okai, Chiori Onoue, Ryo Tsuda, Chihiro Ishigami, Chie Yoshida-Mishima, Naoto Urano, Chiaki Kato, Masami Ishida
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: -
- NAID
  40022381056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07870
[Journal Article] Comamonas sp. 3ah48 a dibenz[a, h] anthracene degrading bacteria that is tolerant to heavy metal.2019
- Author(s)
  M. Okai, Y. Ohki, S. Yamamoto, M. Takashio, M. Ishida, N. Urano
- Journal Title
  
  Lett. Appl. Microbiol.
  
  Volume: 68 Issue: 6 Pages: 589-596
- DOI
  10.1111/lam.13158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06241
[Journal Article] Molecular Phylogeny and Phenotypic Characterization of Yeasts with a Broad Range of pH Tolerance Isolated from Natural Aquatic Environments2019
- Author(s)
  Naoto Urano, Ayaka Shirao, Yuka Naito, Masahiko Okai, Masami Ishida, Masachika Takashio
- Journal Title
  
  Adavances in Microbiology
  
  Volume: 9 Issue: 01 Pages: 56-73
- DOI
  10.4236/aim.2019.91005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] Effect of Acid Species on Cryptococcus sp. T1 and Construction of Its Bioreactor System for Continuous Neutralization of Acidic Media2019
- Author(s)
  Shintato Nagaoka, Yuko Kajiwara, Sayaka Toyama, Masahiko Okai, Masami Ishida, Naoto Urano
- Journal Title
  
  Advances in Microbiology
  
  Volume: 9 Issue: 01 Pages: 74-86
- DOI
  10.4236/aim.2019.91006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] 強酸性環境を中和する酵母2018
- Author(s)
  浦野直人、長岡真太郎、岡井公彦
- Journal Title
  
  科学・技術研究
  
  Volume: 7 Pages: 27-33
- NAID
  130007402925
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] Characterization of yeasts capable of neuralizing acidic media from natural neutral environments2018
- Author(s)
  Shintaro Nagaoka, Takako Kobayashi, Yuko Kajiwara, Masahiko Okai, Masami Ishida, Naoto Urano
- Journal Title
  
  Advances in Microbiology
  
  Volume: 7 Pages: 887-897
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] Neutralization of acidic drainage by Cryputococcous sp. by immobilied in alginate beads2017
- Author(s)
  Masahiko Okai, Chisato Suwa, Shintaro Nagaoka, Nobuo Obara, Masami, Ishida, Naoto Urano
- Journal Title
  
  Bioscience, Bioctechnology, and Biochemistry
  
  Volume: 81(11) Pages: 2216-2224
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] Isolation of aquatic yeasts with the ability to neutralize acidic media, from an extremely acidic river near Japan's Kusatsu-Shirane Volacano2017
- Author(s)
  Daisuke Mitsuya, Takuya Hayashi, Yu Wang, Mami Tanaka, Masahiko Okai, Masami Ishida, and Naoto Urano
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 124(1) Pages: 43-46
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] 水圏に生息する天然酵母の単離と有効利用2016
- Author(s)
  浦野直人、三矢太亮、岡井公彦
- Journal Title
  
  生物工学会誌
  
  Volume: 第6号 Pages: 319-323
- Open Access
- Data Source
  KAKENHI-PROJECT-16K07868
[Journal Article] Crystal structure and site-directed mutagenesis analyses of haloalkane dehalogenase LinB from Sphingobium sp. MI1205.2013
- Author(s)
  Masahiko Okai, Jun Ohtsuka, Fabiana L. Imai, Tomoko Mase, Ryota Moriuchi, Masataka Tsuda, Koji Nagata, Yuji Nagata, Masaru Tanokura
- Journal Title
  
  J. Bacteriol.
  
  Volume: 195 Issue: 11 Pages: 2642-2651
- DOI
  10.1128/jb.02020-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24658068, KAKENHI-PROJECT-25292043
[Presentation] Acropora digitifera由来抗菌ペプチドDigitiferinの作用機序予測2023
- Author(s)
  青山華子，岡井公彦，小川展弘，福丸璃子, 石田真巳, 井上広滋，高木俊幸
- Organizer
  日本サンゴ礁学会第26回大会
- Data Source
  KAKENHI-PROJECT-21K05768
[Presentation] サンゴ由来抗菌ペプチドの発見とVibrio属細菌に対する抗菌活性評価2023
- Author(s)
  青山華子、岡井公彦、小川展弘、福丸璃子、石田真巳、井上広滋、高木俊幸
- Organizer
  日本微生物生態学会　第36回大会
- Data Source
  KAKENHI-PROJECT-21K05768
[Presentation] Vibrio属細菌に対するコユビミドリイシ抗菌ペプチドの活性評価2022
- Author(s)
  青山華子, 高木俊幸, 福丸璃子, 岡井公彦, 井上広滋
- Organizer
  日本サンゴ礁学会
- Data Source
  KAKENHI-PROJECT-21K05768
[Presentation] コユビミドリイシに由来する新規抗菌ペプチドの機能解析2022
- Author(s)
  青山華子, 高木俊幸, 福丸璃子, 岡井公彦, 井上広滋
- Organizer
  東京大学生命科学ネットワーク
- Data Source
  KAKENHI-PROJECT-21K05768
[Presentation] コユビミドリイシ由来の新規抗菌ペプチドの発見と異種発現系を用いた抗菌スペクトル評価2022
- Author(s)
  青山華子, 高木俊幸, 福丸璃子, 岡井公彦, 井上広滋
- Organizer
  マリンバイオテクノロジー学会
- Data Source
  KAKENHI-PROJECT-21K05768
[Presentation] イソガニ体液テトロドトキシン結合タンパク質の一次構造2021
- Author(s)
  長島裕二、藤本健太、石崎松一郎、木谷洋一郎、佐藤根妃奈、岡井公彦
- Organizer
  令和3年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-19K06241
[Presentation] 海洋好冷菌Moritella sp. F1由来Lip I リパーゼの配列分析とLip I・Lip II 遺伝子対の分布2019
- Author(s)
  加賀谷慧、岡井公彦、浦野直人、加藤千明、石田真巳
- Organizer
  極限環境生物学会2018年度（第19回）年会
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 海洋好冷菌Moritella sp. F1由来の新規リパーゼLip I　組換え大腸菌での高効率生産と基質特異性2019
- Author(s)
  加賀谷敬、岡井公彦、浦野直人、加藤千明、石田真巳
- Organizer
  第20回極限環境生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 海洋低温菌PRプロテアーゼおよびQ301P変異型酵素の推定構造・活性・熱安定性・圧力特性の比較2018
- Author(s)
  尾上千桜里、石上千尋、岡井公彦、浦野直人、加藤千明、石田真巳
- Organizer
  第20回マリンバイオテクノロジー学会大会
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 海洋好冷菌 Moritella sp. F1由来好圧性リパーゼF1-LipIIの大腸菌を用いる高効率生産2018
- Author(s)
  清水拓真、木暮梨花、岡井公彦、浦野直人、加藤千明、石田真巳
- Organizer
  第20回マリンバイオテクノロジー学会大会
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 強酸性水圏由来微生物に関する研究11：アルカリ化酵母による酸性水中和の分子機構解析2018
- Author(s)
  長岡真太郎、梶原優子、岡井公彦、石田真巳、浦野直人
- Organizer
  平30年度日本水産学会春期大会
- Data Source
  KAKENHI-PROJECT-16K07868
[Presentation] 強酸性水圏由来微生物に関する研究12：アルカリ化酵母による強酸性水中和システムに及ぼすアルミニウムイオンの影響2018
- Author(s)
  梶原優子、長岡真太郎、岡井公彦、石田真巳、浦野直人
- Organizer
  平成30年度日本水産学会春期大会
- Data Source
  KAKENHI-PROJECT-16K07868
[Presentation] Moritella sp. F1好圧性リパーゼとF3非好圧性リパーゼの一次構造と組換え酵素の性質の比較2017
- Author(s)
  木暮梨花、清水拓真、岡井公彦、浦野直人、加藤千明、石田真巳
- Organizer
  環境微生物系学会合同大会2017
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] Moritella sp. F1株由来好圧性リパーゼF1-lipⅡの大腸菌における生産条件の検討2017
- Author(s)
  清水拓真, 岡井公彦, 浦野直人, 加藤千明, 石田真巳
- Organizer
  第18回極限環境生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 新規Moritella sp. F1・F3株の同定及びF1株由来好圧性リパーゼⅡ遺伝子の大腸菌での発現2017
- Author(s)
  清水拓真, 下川賢大, 岡井公彦, 浦野直人, 関口峻允, 能木裕一, 加藤千明, 石田真巳
- Organizer
  環境微生物系学会合同大会2017
- Data Source
  KAKENHI-PROJECT-16K07870
[Presentation] 強酸性水圏由来微生物に関する研究9：アルカリ化酵母・酵素による酸性水中和機構の解明2016
- Author(s)
  長岡真太郎、梶原優子、岡井公彦、石田真巳、浦野直人
- Organizer
  平成28年度日本水産学会秋季大会
- Place of Presentation
  近畿大学農学部奈良キャンパス
- Data Source
  KAKENHI-PROJECT-16K07868
[Presentation] 強酸性水圏由来微生物に関する研究10：アルカリ化酵母・酵素バイオリアクターによる強酸性水の中和システムも構築2016
- Author(s)
  梶原優子、長岡真太郎、岡井公彦、石田真巳、浦野直人
- Organizer
  平成28年度日本水産学会秋季大会
- Place of Presentation
  近畿大学農学部奈良キャンパス
- Data Source
  KAKENHI-PROJECT-16K07868

1. Ishida Masami (80223006)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Nagata Yuji (30237531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TSUDA MASATAKA (90172022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OHTSUBO YOSHIYUKI (40342761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TANOKURA MASARU (60136786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Urano Naoto (90262336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. Nagashima Yuji (40180484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 佐藤根妃奈 (60579291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 木谷洋一郎 (70565340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 高木俊幸 (00814526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 荒川久幸 (40242325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 磯辺篤彦 (00281189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 横田賢史 (00313388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 上嶋紘生 (10758288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 内田圭一 (50313391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮崎唯史 (70242328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 奥村裕 (80371805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Jiri Damborsky

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Zbynek Prokop

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 石田真己

# of Collaborated Projects: 0 results

# of Collaborated Products: 17 results
21. 吉田尊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okai Masahiko 岡井 公彦

OKAI MASAHIKO 岡井 公彦

Research Projects

Research Products

Co-Researchers

Spatio-temporal dynamics of deterioration of marine microplastics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of structure-function relationship of antimicrobial peptides from the coral Acropora digitiferaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure and function of pufferfish toxin, tetrodotoxin, binding proteins as biological defense agent

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of neutralization of acid envirnments by alkalinization yeasts and their enzymes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural feature of nobel piezophilic lipases from marine piezophilic psychrophile

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of initial degradation system of DDT using enzymes with modified substrate specificityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for acquiring ability to degrade novel compounds in sphingomonads and their applications

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Heterologous expression and functional characterization of cysteamine dioxygenase from the deep-sea mussel Bathymodiolus septemdierum2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary Structure and Conformation of a Tetrodotoxin-Binding Protein in the Hemolymph of Non-Toxic Shore Crab Hemigrapsus sanguineus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Q301P mutant of Vibrio PR protease affects activities under low-temperature and high-pressure conditions2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Comamonas sp. 3ah48 a dibenz[a, h] anthracene degrading bacteria that is tolerant to heavy metal.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Phylogeny and Phenotypic Characterization of Yeasts with a Broad Range of pH Tolerance Isolated from Natural Aquatic Environments2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Acid Species on Cryptococcus sp. T1 and Construction of Its Bioreactor System for Continuous Neutralization of Acidic Media2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 強酸性環境を中和する酵母2018

Author(s)

Journal Title

Okai Masahiko 岡井公彦

OKAI MASAHIKO 岡井公彦

[Presentation] 海洋好冷菌Moritella sp. F1由来の新規リパーゼLip I　組換え大腸菌での高効率生産と基質特異性2019