Fujigaki Hidetsugu 藤垣英嗣

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FUJIGAKI HIDETSUGU 藤垣英嗣

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Researcher Number	00612631
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医療科学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 藤田医科大学, 保健学研究科, 准教授 2023: 藤田医科大学, 医療科学研究科, 准教授 2018 – 2021: 藤田医科大学, 保健学研究科, 講師 2017: 藤田保健衛生大学, 医療科学部, 講師 2014 – 2015: 広島国際大学, 保健医療学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 37030:Chemical biology-related / Chemical biology / Laboratory medicine Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Applied health science / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Keywords	Principal Investigator トリプトファン代謝 / 液性免疫 / SARS-CoV-2 / 腎障害 / 副作用 / シスプラチン / キヌレニンアミノトランスフェラーゼ / キヌレン酸 / 統合失調症 / うつ病 / キヌレニン … More Except Principal Investigator … More 生活習慣病 / 先制医療 / トリプトファン代謝 / 時系列データベース / 生活習慣病予測モデル / 暦年的データベース / 機械学習 / 糖尿病 / IDO2 / 脂質代謝 / インドールアミン酸素添加酵素２ / インシュリン抵抗性 / トリプトファン代謝酵素 / メタボローム / ビックデータ / ストレス / ビッグデータ解析 / トリプトファン代謝産物 / 抑うつ / バイオマーカー / 出生時体重 / 周産期栄養状態 / 周産期うつ / 産後うつ病 / アミノ酸代謝 / 周産期うつ病 Less

多角的なSARS-CoV-2免疫獲得状況の調査研究Principal Investigator
- Principal Investigator
  
  藤垣英嗣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Fujita Health University
時系列データベースを活用した生活習慣病予測モデルの構築および検証
- Principal Investigator
  
  齋藤邦明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
Development of novel cancer treatment strategies to reduce the side effects of cisplatinPrincipal Investigator
- Principal Investigator
  
  Fujigaki Hidetsugu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Fujita Health University
Deficiency of indoleamine 2,3-dioxygenase 2 is associated with the development of lifestyle-related diseases.
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Fujita Health University
Development of novel therapeutic agents for schizophrenia based on kynurenine hypothesisPrincipal Investigator
- Principal Investigator
  
  Fujigaki Hidetsugu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Fujita Health University
Tryptophan metabolic profile is effective for preemptive medicine in depression symptoms
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Fujita Health University
Development of an enzymatic assay for the determination of kynureninePrincipal Investigator
- Principal Investigator
  
  FUJIGAKI HIDETSUGU
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hiroshima International University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass2024
- Author(s)
  Hayashi Ryosuke、Takami Yoshiyuki、Fujigaki Hidetsugu、Amano Kentaro、Akita Kiyotoshi、Yamana Koji、Maekawa Atsuo、Saito Kuniaki、Takagi Yasushi
- Journal Title
  
  The International Journal of Artificial Organs
  
  Volume: 47 Issue: 3 Pages: 147-154
- DOI
  10.1177/03913988241234475
- Data Source
  KAKENHI-PROJECT-23K27843
[Journal Article] Identification of 2′,4′,6′-Trihydroxyacetophenone as Promising Cysteine Conjugate Beta-Lyase Inhibitor for Preventing Cisplatin-Induced Nephrotoxicity2023
- Author(s)
  Sukeda Nao、Fujigaki Hidetsugu、Ando Tatsuya、Ando Honomi、Yamamoto Yasuko、Saito Kuniaki
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 22 Issue: 7 Pages: 873-881
- DOI
  10.1158/1535-7163.mct-22-0564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05757
[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023
- Author(s)
  Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 4 Pages: 462-471
- DOI
  10.1007/s12185-023-03648-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
[Journal Article] Establishment of Model Mice to Evaluate Low Niacin Nutritional Status2023
- Author(s)
  MIZUTANI Amane、SATO Miu、FUJIGAKI Hidetsugu、YAMAMOTO Yasuko、SAITO Kuniaki、HATAYAMA Sho、FUKUWATARI Tsutomu
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 69 Issue: 5 Pages: 305-313
- DOI
  10.3177/jnsv.69.305
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2023-10-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16800, KAKENHI-PROJECT-22K11891
[Journal Article] Comparison of the Serial Humoral Immune Response according to the Immunosuppressive Treatment after SARS-CoV-2 mRNA Vaccination2023
- Author(s)
  Menjo Hiroya、Hasegawa Midori、Fujigaki Hidetsugu、Ishihara Takuma、Minatoguchi Shun、Koide Shigehisa、Hayashi Hiroki、Saito Midori、Takahashi Kazuo、Ito Hiroyasu、Yuzawa Yukio、Saito Kuniaki、Tsuboi Naotake
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 23 Pages: 3445-3454
- DOI
  10.2169/internalmedicine.1949-23
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-12-01
- Language
  English
- Data Source
  KAKENHI-PROJECT-23K27843
[Journal Article] A Phase I/II Clinical Trial of Intradermal, Controllable Self-Replicating Ribonucleic Acid Vaccine EXG-5003 against SARS-CoV-22023
- Author(s)
  Koseki Takenao、Teramachi Mayumi、Koga Minako、Ko Minoru S. H.、Amano Tomokazu、Yu Hong、Amano Misa、Leyder Erica、Badiola Maria、Ray Priyanka、Kim Jiyoung、Ko Akihiro C.、Achour Achouak、Weng Nan-ping、Imai Takumi、Yoshida Hisako、Taniuchi Satsuki、Shintani Ayumi、Fujigaki Hidetsugu、Kondo Masashi、Doi Yohei
- Journal Title
  
  Vaccines
  
  Volume: 11 Issue: 12 Pages: 1767-1767
- DOI
  10.3390/vaccines11121767
- Data Source
  KAKENHI-PROJECT-23K27843
[Journal Article] The Trajectory of the COVID-19 Vaccine Antibody Titers Over Time and the Association of Mycophenolate Mofetil in Solid Organ Transplant Recipients.2022
- Author(s)
  Sakai A, Morishita T, Suzumura K, Hanatate F, Yoshikawa T, Sasaki N, Lee S, Fujita K, Hara T, Araki H, Tagami A, Murayama M, Yamada R, Iwata A, Sobajima T,Kasahara Y, Matsuzawa Y, Takemura M, Yamamoto Y, Fujigaki H, Saito K, Tsurumi H,　Matsunami H.
- Journal Title
  
  Transplant Proc.
  
  Volume: 54(10) Issue: 10 Pages: 2638-2645
- DOI
  10.1016/j.transproceed.2022.10.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11891
[Journal Article] CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma2022
- Author(s)
  Okamoto Akinao、Fujigaki Hidetsugu、Iriyama Chisako、Goto Naoe、Yamamoto Hideyuki、Mihara Keichiro、Inaguma Yoko、Miura Yasuo、Furukawa Katsuya、Yamamoto Yukiya、Akatsuka Yoshiki、Kasahara Senji、Miyao Kotaro、Kajiya Ryoko、Okamoto Masataka、Saito Kuniaki、Tomita Akihiro
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 11 Pages: 3230-3233
- DOI
  10.1182/bloodadvances.2021006302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-23K24297
[Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021
- Author(s)
  Mori Yuko、Mouri Akihiro、Kunisawa Kazuo、Hirakawa Mami、Kubota Hisayoshi、Kosuge Aika、Niijima Moe、Hasegawa Masaya、Kurahashi Hitomi、Murakami Reiko、Hoshi Masato、Nakano Takashi、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 405 Pages: 113191-113191
- DOI
  10.1016/j.bbr.2021.113191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
[Journal Article] Indoleamine 2,3‐dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma2019
- Author(s)
  Yamasuge Wakana、Yamamoto Yasuko、Fujigaki Hidetsugu、Hoshi Masato、Nakamoto Kentaro、Kunisawa Kazuo、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3061-3067
- DOI
  10.1111/cas.14179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-18K15377
[Journal Article] Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia2019
- Author(s)
  Fujigaki Hidetsugu、Mouri Akihiro、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Neurochemistry International
  
  Volume: 125 Pages: 1-6
- DOI
  10.1016/j.neuint.2019.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969
[Journal Article] Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues2019
- Author(s)
  Yoshida Yukihiro、Fujigaki Hidetsugu、Kato Koichi、Yamazaki Kyoka、Fujigaki Suwako、Kunisawa Kazuo、Yamamoto Yasuko、Mouri Akihiro、Oda Akifumi、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10243-10243
- DOI
  10.1038/s41598-019-46666-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K08257, KAKENHI-PROJECT-18K15377
[Journal Article] Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling2018
- Author(s)
  Yamamoto Yasuko、Yamasuge Wakana、Imai Shinjiro、Kunisawa Kazuo、Hoshi Masato、Fujigaki Hidetsugu、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 15917-15917
- DOI
  10.1038/s41598-018-34166-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K15377
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacology.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K.
- Journal Title
  
  j.neuropharm.
  
  Volume: S0028-3908(16) Pages: 30011-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K
- Journal Title
  
  Neuropharmacology.
  
  Volume: 印刷中 Pages: 264-274
- DOI
  10.1016/j.neuropharm.2016.01.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860379, KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675
[Journal Article] Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1.2016
- Author(s)
  Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K.
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: 6 Issue: 1 Pages: 29920-29920
- DOI
  10.1038/srep29920
- NAID
  120006323748
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-15H04100, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948
[Patent] 腎障害の治療方法または予防方法において使用するための医薬組成物および当該医薬組成物を含む併用薬、並びに、CCBL1阻害剤2023
- Inventor(s)
  藤垣英嗣、齋藤邦明
- Industrial Property Rights Holder
  学校法人藤田学園
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2024
- Data Source
  KAKENHI-PROJECT-20K05757
[Patent] 腎障害の治療方法または予防方法において使用するための医薬組成物および当該医薬組成物を含む併用薬2022
- Inventor(s)
  藤垣英嗣、齋藤邦明
- Industrial Property Rights Holder
  学校法人藤田学園藤田医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-083331
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K05757
[Patent] キヌレニンアミノトランスフェラーゼ2(KAT2)阻害剤2019
- Inventor(s)
  藤垣英嗣, 齋藤邦明
- Industrial Property Rights Holder
  藤垣英嗣, 齋藤邦明
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-061581
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K01969
[Patent] キヌレニンアミノトランスフェラーゼ２（ＫＡＴ２）阻害剤2019
- Inventor(s)
  藤垣英嗣、齋藤邦明
- Industrial Property Rights Holder
  学校法人藤田学園
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-061581
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] ワクチン接種による免疫獲得者とハイブリッド免疫獲得者の血清中抗SARS-C0V-2抗体価の推移の違い2023
- Author(s)
  杉浦彩香、藤垣英嗣、高尾明日香、加藤詩緒、水谷宗慈、山本康子、竹村正男、齋藤邦明
- Organizer
  日本医療検査科学会第55回大会
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] COV2ファイナルアンサー～検査とワクチンのこれから～2023
- Author(s)
  藤垣英嗣
- Organizer
  日本医療検査科学会第55回大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] 暦年的なデータベースを用いた機械学習による高血圧予備群の予測2023
- Author(s)
  水谷宗慈、山本康子、竹村正男、藤垣英嗣、齋藤邦明
- Organizer
  第63回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] 生体分子間相互作用解析装置を用いた血清中抗新型コロナウイルス抗体とウイルスの結合親和性の評価2023
- Author(s)
  高尾明日香、藤垣英嗣、杉浦彩香、小森隆弘、斉藤憲佑、竹村正男、齋藤邦明
- Organizer
  日本医療検査科学会第55回大会
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] 質量分析計を用いた新型コロナウイルス感染症患者血清中のトリプトファン代謝産物一斉定量解析2023
- Author(s)
  藤垣英嗣、高尾明日香、杉浦彩香、藤垣朱和子、生野彰宏、山本康子、齋藤邦明
- Organizer
  第42回日本トリプトファン研究会学術集会
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] 生化学自動分析装置JCA-BM9130を用いた新型コロナウイルス抗体検査試薬「SARS-CoV-2 UTAB FS」の有用性の検討2022
- Author(s)
  藤垣英嗣, 竹村正男, 齊藤翠, 藤田孝, 山本康子, 齋藤邦明
- Organizer
  医学と薬学
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] ADVIA Centaur XPTによるIL-6測定の基礎的検討と臨床的意義関節リウマチ患者を対象に検討2022
- Author(s)
  石田秀和, 竹村正男, 佐藤正夫, 山本康子, 藤垣英嗣, 佐々木智裕, 森本剛史, 酒井昭嘉, 伊藤弘康, 斉藤邦明
- Organizer
  医療検査と自動化
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] Indoleamine 2,3-dioxygenase 2 (IDO2)欠失による乾癬病態増悪のメカニズム解明2021
- Author(s)
  酒井里佳, 山本康子、藤垣英嗣、齋藤邦明
- Organizer
  日本トリプトファン研究会第40回学術集会
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] Indoleamine 2,3-dioxygenase 2 (IDO2)欠失による乾癬病態増悪のメカニズム解明2021
- Author(s)
  酒井里佳, 山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第15回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] Cysteine conjugate beta-lyase1 阻害剤によるCisplatin 誘発性腎障害保護効果2021
- Author(s)
  助田菜緒，藤垣英嗣，安藤穂乃実，山本康子，齋藤邦明
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K05757
[Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020
- Author(s)
  山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第67回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020
- Author(s)
  山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] グリチルリチン酸とその類似体はキヌレニンアミノトランスフェラーゼ2活性を阻害する2019
- Author(s)
  藤垣英嗣，吉田幸弘，加藤紘一，小田彰史，山本康子，鍋島俊隆，齋藤邦明
- Organizer
  第39回日本トリプトファン研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] Tryptophan metabolites as a potential tumor marker2019
- Author(s)
  Fujigaki Hidetsugu
- Organizer
  15th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] Development and Validation of a Liquid Chromatography Tandem Mass Spectrometry Method for the Measurement of Tryptophan Metabolites2019
- Author(s)
  Hidetsugu Fujigaki, Reiko Murakami, Yasuko Yamamoto, Kuniaki Saito
- Organizer
  The 57th Congress of the Korean Association of Medical Technoligists and International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-2019
- Author(s)
  毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019（2019/8/31東京）
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 液体クロマトグラフ質量分析計(LC-MS)によるトリプトファン代謝産物一斉定量解析2019
- Author(s)
  木村文香, 村上怜子, 藤垣英嗣, 國澤和生, 毛利彰宏, 仲本賢太郎, 山本康子, 鍋島俊隆, 齋藤邦明
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] 酵素反応を用いたキノリン酸測定法の開発2018
- Author(s)
  山崎杏佳, 藤垣英嗣, 吉田幸弘, 木村文香, 山本康子, 齋藤邦明
- Organizer
  第５８回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Exposure to valproic acid during pregnancy induces autism endophenotypes in the male offspring2018
- Author(s)
  Mami HIrakawa, Akihiro Mouri, Kazuo Kunisawa, Yuko Mori, Moe Niijima ,Hisayoki Kubota, Tomoaki Teshigawara, Hidetsugu Fujigaki, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Development of animal models and biomarker for depression focused on serotonergic systems2018
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto , Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Development of Kynurenine aminotransferase II inhibitor screening assay2018
- Author(s)
  Kyoka Yamazaki, Hidetsugu Fujigaki, Yukihiro Yoshida, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  15th International Society for Tryptophan Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] Kynurenine 3-monooxygenase is essential for de novo biosynthesis of NAD2018
- Author(s)
  Yukihiro Yoshida, Hidetsugu Fujigaki, Yasuko Yamamoto, Kyoka Yamazaki, Tsutomu Fukuwatari, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  15th International Society for Tryptophan Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] Characterization and n-glycosylation detection of human kynurenine 3-monooxygenase2018
- Author(s)
  Fumika Kimura, Hidetsugu Fujigaki, Yukihiro Yoshida, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  15th International Society for Tryptophan Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] トリプトファン・キヌレニン代謝経路の変動と精神神経疾患2018
- Author(s)
  藤垣英嗣
- Organizer
  第58回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] 神経精神疾患の病態メカニズムに基づく新たな治療分子標的トリプトファン代謝に注目したうつ病病態解明と診断・治療薬戦略2018
- Author(s)
  毛利彰宏, 國澤和生, 山本康子, 藤垣英嗣, 齋藤邦明, 鍋島俊隆
- Organizer
  第２８回日本臨床精神神経薬理学会・第４８回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018
- Author(s)
  松下祥子, 高橋和男, 伊藤辰将, 山本康子, 藤垣英嗣, 毛利彰宏, 中嶋和紀, 尾之内高慶, 辰川英樹, 釘田雅則, 長尾静子, 人見清隆, 齋藤邦明, 瀬藤光利, 湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 酵素法を用いたキヌレニン定量法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] 酵素法を用いたキヌレニン定量法の開発2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討．2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K01969
[Presentation] 組換えキヌレニンアミノ基転移酵素2の発現・精製と生化学的解析2015
- Author(s)
  藤川紗英、藤垣英嗣、松尾円香、三東由樹、速水啓介、板羽秀之、山本康子、斉藤邦明
- Organizer
  第10回日本臨床検査学教育学会学術大会
- Place of Presentation
  信州大学医学部
- Year and Date
  2015-08-19
- Data Source
  KAKENHI-PROJECT-26860379
[Presentation] A rapid and highly sensitive method to evaluate the quinolinic acid using recombinant enzymes with HPLC-fluorescence detection.2015
- Author(s)
  Hidetsugu Fujigaki, Akiko Sakamoto-Morise, Suwako Fujigaki, Kanako Hirabayashi-Takahashi, Masato Hoshi, Yasuko Yamamoto, Sanford P. Markey, and Kuniaki Saito
- Organizer
  The 14th International Society for Tryptophan Research Conference
- Place of Presentation
  Van Andel Research Institute in Grand Rapids, Michigan (USA)
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-26860379
[Presentation] キヌレニン酸素添加酵素の生化学的特性の解析とN結合型糖鎖の検出2015
- Author(s)
  松尾円香、藤垣英嗣、石田有里、三東由樹、藤川紗英、川本雅也、笹根真介、山本康子、斉藤邦明
- Organizer
  第38回日本分子生物学会年回・第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860379
[Presentation] バキュロウイルス／昆虫細胞発現系を用いた組換えキヌレニン酸素添加酵素の精製と生化学的解析2015
- Author(s)
  三東由樹、藤垣英嗣、松尾円香、藤川紗英、速水啓介、板羽秀之、山本康子、斉藤邦明
- Organizer
  第10回日本臨床検査学教育学会学術大会
- Place of Presentation
  信州大学医学部
- Year and Date
  2015-08-19
- Data Source
  KAKENHI-PROJECT-26860379

1. Yamamoto Yasuko (00331869)

# of Collaborated Projects: 6 results

# of Collaborated Products: 26 results
2. Saito Kuniaki (80262765)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 毛利彰宏 (20597851)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 服部恭尚 (20567028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 星雅人 (40633996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石川浩章 (50321013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 寺本篤司 (00513780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 近藤征史 (00378077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 長谷川みどり (40298518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 成瀬寛之 (50319266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坪井直毅 (50566958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 古関竹直 (70850551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 伊藤弘康 (80373075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 冨田章裕 (80378215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岡本晃直 (80775049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. ITO Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 斉藤邦明

# of Collaborated Projects: 0 results

# of Collaborated Products: 21 results
18. 葉名尻良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujigaki Hidetsugu 藤垣 英嗣

FUJIGAKI HIDETSUGU 藤垣 英嗣

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多角的なSARS-CoV-2免疫獲得状況の調査研究Principal Investigator

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時系列データベースを活用した生活習慣病予測モデルの構築および検証

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Development of novel cancer treatment strategies to reduce the side effects of cisplatinPrincipal Investigator

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Deficiency of indoleamine 2,3-dioxygenase 2 is associated with the development of lifestyle-related diseases.

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Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.

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Development of novel therapeutic agents for schizophrenia based on kynurenine hypothesisPrincipal Investigator

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Tryptophan metabolic profile is effective for preemptive medicine in depression symptoms

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Development of an enzymatic assay for the determination of kynureninePrincipal Investigator

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[Journal Article] Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass2024

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[Journal Article] Identification of 2′,4′,6′-Trihydroxyacetophenone as Promising Cysteine Conjugate Beta-Lyase Inhibitor for Preventing Cisplatin-Induced Nephrotoxicity2023

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[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023

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[Journal Article] Establishment of Model Mice to Evaluate Low Niacin Nutritional Status2023

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[Journal Article] Comparison of the Serial Humoral Immune Response according to the Immunosuppressive Treatment after SARS-CoV-2 mRNA Vaccination2023

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Fujigaki Hidetsugu 藤垣英嗣

FUJIGAKI HIDETSUGU 藤垣英嗣