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Hirunagi Tomoki  蛭薙 智紀

ORCIDConnect your ORCID iD *help
Researcher Number 00927527
Other IDs
Affiliation (Current) 2025: 名古屋大学, 高等研究院(医), 特任助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 名古屋大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related
Except Principal Investigator
Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related
Keywords
Principal Investigator
超早期病態 / 球脊髄性筋萎縮症 / ポリグルタミン病 / RAN翻訳 / 細胞非自律性メカニズム / 超早期治療 / 核酸医薬 / シナプス関連遺伝子
Except Principal Investigator
神経変性疾患 / 核酸 … More / 運動ニューロン / 球脊髄性筋萎縮症 / 運動ニューロン疾患 / 神経変性 / タンパク質凝集体 / シヌクレイン / ポリグルタミン / タンパク質凝集 / 凝集タンパク質 / 低分子干渉RNA / アンチセンス核酸 / イオンチャンネル / 転写障害 / 早期病態 / シングルセル解析 / 胎児 / マルチモーダル解析 / オリゴデンドロサイト / 軸索 / 脊髄性筋萎縮症 Less
  • Research Projects

    (6 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (8 People)
  •  ポリグルタミン病の超早期病態における非細胞自律性メカニズムの解明Principal Investigator

    • Principal Investigator
      蛭薙 智紀
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University
  •  Development of next-generation antisense therapeutics for neurological diseases

    • Principal Investigator
      佐橋 健太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University
  •  Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseases

    • Principal Investigator
      勝野 雅央
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University
  •  The pathogenesis of neurodegeneration in the very early stage of polyglutamine disease and the development of nucleic acid therapy in polyglutamine diseasesPrincipal Investigator

    • Principal Investigator
      Hirunagi Tomoki
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University
  •  Understanding of early axonal pathology in motor neuron diseases

    • Principal Investigator
      Sahashi Kentaro
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University
  •  Therapeutic development against protein aggregation

    • Principal Investigator
      佐橋 健太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

All 2024 2023

All Journal Article Presentation

  • [Journal Article] Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy.2024

    • Author(s)
      Hirunagi T, Nakatsuji H, Sahashi K, Yamamoto M, Iida M, Tohnai G, Kondo N, Yamada S, Murakami A, Noda S, Adachi H, Sobue G, Katsuno M.
    • Journal Title

      J Cachexia Sarcopenia Muscle

      Volume: 15 Issue: 1 Pages: 159-172

    • DOI

      10.1002/jcsm.13344

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06976, KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-23H00420
  • [Presentation] Single cell analysis reveals oligodendrocyte heterogeneity in spinal and bulbar muscular atrophy2023

    • Author(s)
      飯田 円, 佐橋 健太郎, 蛭薙 智紀, 榊原 健二, 前田 憲多郎, 紅 朋浩, 日野原 邦彦, 勝野 雅央
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-23H00420
  • 1.  Sahashi Kentaro (90710103)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  勝野 雅央 (50402566)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  横井 聡 (30815460)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  井口 洋平 (80790659)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  飯田 円 (40815437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  阿部 洋 (80415067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  浅沼 浩之 (20282577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ADACHI Hiroaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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