Uchiyama Yasuo 内山安男

… Alternative Names

UCHIYAMA Yasuo 内山安男

山内安男ヤマウチヤスオ

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Researcher Number	10049091
Other IDs
External Links
Affiliation (Current)	2024: 順天堂大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 順天堂大学, 医学部, 特任教授 2017: 順天堂大学, 老人性疾患病態・治療研究センター, センター長 2008 – 2015: Juntendo University, 医学部, 教授 2012 – 2013: 順天堂大学, 医学部, 特任教授 1999 – 2007: 大阪大学, 医学系研究科, 教授 … More 2000 – 2005: 大阪大学, 大学院・医学系研究科, 教授 2004: 阪大, 医学(系)研究科(研究院), 教授 1998 – 2004: 大阪大学, 大学院・医学研究科, 教授 2002: 大阪大学, 大学院医学系・研究科・情報伝達医学機能形態学, 教授 2001: 大阪大学, 医学研究科, 教授 2001: 大阪大学, 大学院・医学系研究科・情報伝達医学機能形態学, 教授 1999 – 2000: 大阪大学, 医学部・解剖, 教授 1998: 大阪大学, 大学院・医学系研究科, 教授 1995 – 1998: 大阪大学, 医学部, 教授 1996: 大阪大学医学部, 教授 1994: 大阪大学, 医学部・解剖学, 教授 1994: 岩手医科大学, 医学部(解剖学), 教授 1993: 岩手医科大学, 医学部・解剖学, 教授 1992 – 1993: 岩手医科大学, 医学部, 教授 1991: 岩手医科大学, 医学部(解剖II), 教授 1987 – 1988: 筑波大学, 基礎医学系, 助教授 Less
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology / Biological Sciences / General anatomy (including histology/embryology) / Biological Sciences Except Principal Investigator General anatomy (including Histology/Embryology) / General surgery / Urology / Biological Sciences … More / Digestive surgery / Biological Sciences / Basic Section 51030:Pathophysiologic neuroscience-related / Neurophysiology / General neuroscience / Neuroscience in general / General anatomy (including Histology/Embryology) / General surgery / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology / Orthopaedic surgery Less
Keywords	Principal Investigator リソソーム / オートファジー / カテプシンD / アポトーシス / LC3 / ノックアウトマウス / カテプシンB / PC12細胞 / bcl-2 / オートファゴソーム … More / 神経細胞死 / 脳虚血 / ユビキチン / PCTF35 / 神経栄養因子 / NBR1 / p62 / spheroid / Tom20 / DFCP1 / Atg9A / 脂肪滴 / RNAi / 細胞死 / 低酸素-脳虚血 / 海馬 / 海馬CA1錐体細胞 / プロテアーゼインヒビター / リソゾーム / 遺伝子導入 / 神経突起 / システインプロテアーゼ / アストログリア / 遅延型神経細胞死 / Pre- and Post-natal development / Circadian variation / Angiotensinogen / Hepatocytes / Rat / insitnハイブリダイゼーション / mRNA / アンギオテンシノーゲン及び同mRNAの肝細胞内局在に関する研究 / 抗アンギオテンシノーゲン / 免疫組織化学 / 生後発達 / 発生 / 日周リズム / アンギオテンシノーゲン / 肝細胞 / ラット / Secretion / Induction / Primary culture / TGF-b1 / Glyosis / Astrocytes / Brain injuries / NGF / 脊髄後根神経節 / ラット新生仔 / 錐体神経細胞 / 海馬CA1領域 / 低酸素虚血障害 / 栄養因子 / TGFB1 / 分泌 / 発現誘導 / 初代培養 / TGFβ1 / グリオーシス / 脳障害 / Dorsal roof ganglion / Lysosomes / Cathepsin D / Cathepsin B / Neurotrophic factor / Bcl-2 gene / PC12 Cells / Apoptosis / CAl錐体細胞 / オートファジ- / nedd-2 / cDNAクローニング / bcl-2遺伝子 / 後根神経節 / bc1-2遺伝子 / ニューロン / 低酸素脳虚血負荷 / DNaseII / プロセッシング / DNase II / 低酸素脳虚血付加 / CAD / LMPCR / 脂肪滴形成 / 神経軸索 / オートファジー（選択的） / ubiquitin / 選択的オートファジー / Atg9 / 軸索 / 3T3-L1細胞 / 培養細胞 / エネルギー代謝 / 小胞体膜 / 欠損マウス / LC3A / LC3B / DNAマイクロアレイ / 海馬CA1錘体細胞死 / 低酸素能虚血負荷 / Atg7-KOマウス / プロテアーゼ / カテプシンL / Atg7欠損マウス / LC3欠損マウス / 低酸素脳虚血傷害 / 脂肪代謝 / リソソームプロテアーゼ / ミュータントマウス / Atg7 / オートファジー性神経細胞死 / カテプシン / 神経細胞 / リン脂質 / Apg4 / 膜結合型LC3-II / 細胞質型LC3-I / バルクタンパク質分解 / インヒビター / オートファジ / 低酸素負荷 / TUNEL染色 / カスパーゼ / CA1錐体細胞 / 低酸素-虚血 / オートファジー性細胞死 / マンノース6-リン酸リセプター / アンチセンス / アスパルギン酸プロテ-ゼ / 自食小胞 / CPP32 / ネクローシス / 小胞体 / 免疫細胞化学 / ミトコンドリア内膜 / PC_<T2>細胞 / Bcl-2 / ニューロフィラメントM / 分化 / 増殖 / PC12細胞株 / アポトーシスの回避 / 海馬CAI錐体細胞 / 遅発性神経細胞死 / 神経発生 / システイプロテアーゼ / ミクログリア / 海馬CAI領域 / システィンプロテア-ゼ … More Except Principal Investigator アポトーシス / オートファジー / エンドトキシン / Endotoxin / ミトコンドリア / ニューロフィラメント / 神経細胞 / リソソーム / NOS陽性神経 / ヒト陰茎海綿体 / 磁気共鳴機能画像法 / 光遺伝学 / 霊長類 / 認知神経科学 / 蛋白質 / 遺伝子 / 脳神経疾患 / Toll-like receptor / Neurofilament / NF-H欠損マウス / 大脳 / MAP Kinases / Caspase-3 / 肝細胞 / KIT / Infection / 神経細胞死 / 神経変性疾患 / apoptosis / 免疫組織細胞化学 / 軸索 / リン酸化 / c-kit / gain-of-function mutation / Interstitial Cells of Cajal / 細胞死 / カスパーゼ / カテプシン / PACAP / VIP / ユビキチン / プロテアーゼ / ビリルビン / 肝障害 / 敗血症 / CGRP陽性神経 / インポテンス / 小胞輸送障害 / βアミロイド / アルツハイマー病 / 記憶 / 磁気刺激法 / メタ記憶 / 生理学 / 細胞・組織 / 細胞内分解 / 磁気共鳴画像法 / 記憶システム / 大域的大脳ネットワーク / 光遺伝子 / 磁気共鳴機能画像法（fMRI） / 解剖学 / 改造学 / 神経科学 / cell death-associated proteins / lysosome / cytoskeletons / polyphenol / axon / neuron / stroke-prone spontaneous hypertensive rat / senescence-accelerated mice / ウエスタンブロット / ウコン / 赤ワイン / 細胞死関連蛋白質 / ライソソーム / 細胞骨格系 / ポリフェノール / 脳卒中易発症性高血圧ラット / 老化促進マウス / Allele / Sunitinib / Imatinib / Molecular target therapy / PDGFRA gene / KIT gene / Molecular mechanism of resistance / Gastrointestinal stromal tumor / PDGFR / ターゲット遺伝子 / 耐性 / 一次耐性 / PDGFRα遺伝子 / 二次耐性 / アリル / スニチニブ / イマチニブ / 分子標的治療 / PDGFRA遺伝子 / KIT遺伝子 / 耐性機構 / 消化管間質腫瘍 / Neuronal cell death / Mitochondria / Microtubule / Organization of axoplasm / and NF-H tail-less mice / NF-M or / NFsubunit-deficient mice / Gene-manipulated mice / NF-Mの発現 / 軸索輸送 / 軸索細胞の構築 / NF-HのC末端除去マウス / 急速連結ディープエッチ法 / ウエスタンブロット法 / NF-H及びNF-M C末端同時除去マウス / NF-M C末端除去マウス / NF-H C末端除去マウス / 神経軸索 / 微小管 / 軸索細胞質の構築 / 及びNFH C末端除去マウス / NF-Mあるいは / NF各サブユニット欠損マウス / 遺伝子操作マウス / Organ failure / Immunosuppression / Innate immunity / Cytokine production / Surgical insult / 感染症 / 外科侵襲 / TNFα / interleukin-6 / till-like receptors / 臓器障害 / 感染 / 免疫抑制 / 自然免疫 / サイトカイン / 手術侵襲 / Double tailless mice / NF-H tailless mice / NF-M tailless mice / NF-H knockut mice / NF-M knockout mice / NF-L knockout mice / crossbridge / 急送凍結ディープエッチ電顕法 / 軸索輸送障害 / NF-L欠損マウス / 軸索機脳障害 / NF-M, NF-H両C末端欠損ノックインマウス / NF-HC末端欠損ノックインマウス / NF-MC末端欠損ノックインマウス / ニューロフィラメント遺伝子操作マウス / 両C末端欠損マウス / NF-HC末端欠損マウス / NF-MC末端欠損マウス / NF-Hノックアウトマウス / NF-Mノックアウトマウス / NF-Lノックアウトマウス / クロスブリッジ / Long-term Depression / Green Fluorescence Protein / GABAergic Neuron / Synaptic Plasticity / Brain-Derived Neurotrophic Factor / Development / Visual Cortex / Cerebral Cortex / カテプシンD / シナプス / 眼優位円柱 / 緑色蛍光蛋白質 / 細胞移動 / 抑制性シナプス / 神経栄養因子 / 長期抑圧 / 緑色蛍光タンパク質 / GABAニューロン / シナプス可塑性 / 脳由来神経栄養因子 / 発達 / 視覚野 / Bile Acids / Bilirubin / Kupffer cell / Hepatocyte / Apotosis / 胆汁鬱滞 / 胆汁酸 / クッパー細胞 / iNOS / nitric oxide / Macrophage / Intestinal motility / 微小循環 / NO / Nitric Oxide / 蠕動運動 / KIT蛋白質 / カハール細胞 / 腸管運動 / Neurodegenerative disease / processing / Endoplasmic Reticulum / Huntinton / polyglutamine disease / ER stress / caspase-12 / レチノイン酸 / BMP-4 / Akt / チトクロームC / Bcl-x / カスパーゼ3 / カスパーゼ9 / 脳形成 / カスパーゼ12 / ポリグルタミン / ハンチントン病 / ER ストレス / カスパーゼー12 / プロセッシング / 小胞体 / ポリグルタミン病 / ERストレス / プログラム細胞死 / Bcl-2 protein / mitochondria / phosphorylation / neurofilament / PC12 cell / dysmyelinating mice / neuronal cell / 電子顕微鏡 / 中枢神経系 / 発現 / アポトーシス(細胞死) / Bc1-2蛋白 / 髄鞘形成不全 / 細胞変性 / Bcl-2蛋白 / PC12細胞 / 髄鞘形成不全マウス / prognosis / recurrence / stromal tumors / proto-oncogene / gastrointestinal tract / 再発 / Interstitial Cells Cajal / 消化管平滑筋腫 / 予後 / 平滑筋腫 / 消化管 / Gastrointestinal Stromal Tumor / joint destruction / myeloid cell / hyaluronan / lymphoid cell / pseudoemparipolesis / nurse cell / rheumatoid arthritis / 蛋白分解酵素 / 接着分子 / 骨・関節破壊 / ナ-ス細胞 / 滑膜細胞 / 骨髄細胞 / 慢性関節リウマチ / 関節破壊 / 骨髄球系細胞 / ヒアルロン酸 / リンパ球 / pseudoemperipolesis / ナース細胞 / RA / CASPASE / APOPTOSIS / CATHEPSIN / CONJUGATION SYSTEM / AUTOPHAGY / LYSOSOME / PROTEOLYSIS / BIOMODULATOR / カルパイン / 恒常性の維持 / 細胞文化 / カルパスタチン / 自食作用 / 細胞分化 / 細胞周期 / 蛋白連結システム / 蛋白分解 / バイオモジュレーター / Serotonin / Urethra / Erection / Corpus cavernosum penis / セロトニン / 尿道 / 勃起 / 陰茎海綿体 / MAP-LC3 / モディファイアータンパク質 / E2酵素 / E1酵素 / ヒトAPGホモログ / 蛋白質分解 / ノックアウトマウス / Atg7 / 静脈閉鎖メカニズム / NPY陽性神経 / VIP陽性神経 / 勃起メカニズム / 加齢変化 / NADPH-diaphorase陽性神経 / PGP9.5陽性神経 Less

in vitro変性神経突起モデルを用いたアルツハイマー病病態進展機序の解明
- Principal Investigator
  
  櫻井隆
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
大脳メタ記憶神経回路の解明：光遺伝学による内省の因果的制御
- Principal Investigator
  
  宮下保司
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Institute of Physical and Chemical Research
  Juntendo University
The polarized localization of p62 and NBR1 in cathepsin D-deficient neurons is involved in selective autophagyPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Juntendo University
Multidisciplinary research on autophagy: from molecular mechanisms to disease states
- Principal Investigator
  
  Mizushima Noboru
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of neural mechanisms of primate cognitive memory using an integrated approach of magnetic resonance imaging and optogenetic manipulation
- Principal Investigator
  
  MIYASHITA Yasushi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
神経軸索におけるタンパク分解機構とその破綻Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Proteolysis in neuronal axons and its impairmentPrincipal Investigator
- Principal Investigator
  
  Uchiyama Yasuo
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Genetic study of molecular characteristic of autophagy-related proteins LC3A and LC3BPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Juntendo University
Searching for novel Dnase executing autophagic cell death.Principal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Juntendo University
Brain Environment
- Principal Investigator
  
  Takahashi Ryosuke
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
脂肪滴形成へのオートファジーの関与についてPrincipal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Juntendo University
Molecular mechanisms of autophagic neuron deathPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Juntendo University
  Osaka University
Molecular mechanisms of drug resistance in cancer.-GIST resistant to imatinib as a model-
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Axonal degenerations with aging and their rescue by genetic and nutritional manipulations
- Principal Investigator
  
  GOTOW Takahiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Koshien University
がん細胞死におけるオートファジー/リソソームプロテアーゼの役割Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
オートフアジー性神経細胞死の制御機構に関する分子細胞生物学的研究Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
オートファジー(自食作用)誘導活性の測定法の開発に関する研究Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
Cytoskeletons and cell death-associated proteins expressed in neuronal cells in the neurofilament gene-manipulated mice
- Principal Investigator
  
  GOTOW Takahiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Koshien University
Mechanisms of immune responses by toll-like receptor against Infection and organ failure
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
オートファジーを担うApgシステム(高等動物)
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
DEVELOPMENT OF PHYSIOLOGICAL FUNCTION OF VISUAL CORTEX
- Principal Investigator
  
  TSUMOTO Tadaharu
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  OSAKA UNIVERSITY
Relationship between neurodegenerative diseases and neurofilaments accumulated in somata and/or axons
- Principal Investigator
  
  GOTOW Takahiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  College of Nutrition, Koshien University
MOLECULAR CELL BIOLOGICAL SYUDY OF A NOVEL NEUROTROPHIC PROTEIN, PCTF35Principal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Osaka University
Detection of the activation of caspases during neuronal cell death by using antiserum specifically recognizing active form of caspases
- Principal Investigator
  
  MOMOI Takashi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute of Neuroscience
Mechanisms of the gastrointestinal motility dysfunction under septic conditions - a role of Interstitial Cells of Cajal -
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Mechanisms of sepsis-induced cholestatic liver injury
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
リソゾームカテプシン群による神経細胞死の新たな制御機構についてPrincipal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
The role of neurofilament and mitochondria in the neuronal cell death
- Principal Investigator
  
  GOTOW Takahiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Koshien University
リソゾームカテプシン群による神経細胞死の新たな制御機構についてPrincipal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Molecular analysis of interaction between hematopoietic cells and nurse cells established from patients with rheumatoid arthritis
- Principal Investigator
  
  OCHI Takahiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Role of the c-kit tyrosine kinase in the genesis of gastrointestinal stromal tumors.
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
原型癌遺伝子bcl-2の遺伝子発現による神経細胞死の回避とその生理的意義Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
敗血症時のエンドトキシンによる肝障害とその発生にアポートシスのはたす役割
- Principal Investigator
  
  NISHIDA Toshirou
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
BIOMODULATOR FUNCTIONS OF PROTEOLYSIS
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  JUNTENDO UNIVERITY
原型癌遺伝子bcl-2の遺伝子発現による神経細胞死の回避とその生理的意義Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
高齢者における静脈性勃起障害の病態解明-特に静脈性閉鎖機構へのNOの関与と障害
- Principal Investigator
  
  萬谷嘉明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Iwate Medical University
Apoptosis of CA1 pyramidal neurons in the hippocampus after brief forebrain ischemia and its preventionPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Osaka University
原型癌遺伝子bcl-2の遺伝子発現による神経細胞死の回避とその生理的意義Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Iwate Medical University
高齢者における陰茎勃起機能低下の解明-特に静脈環流異常におけるNOとCGRPの関与-
- Principal Investigator
  
  萬谷嘉明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Iwate Medical University
神経細胞死におけるリソゾームシステインプロテアーゼの役割Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Iwate Medical University
高齢者における陰茎勃起能低下の解明-特にPGP9.5ならびにNOとの関連について-
- Principal Investigator
  
  萬谷嘉明
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Iwate Medical University
神経細胞死におけるリソゾームシステインプロテアーゼの役割りPrincipal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Iwate Medical University
Localization and functional significance of signal substances in the urogenital tract
- Principal Investigator
  
  FUJITA Tsuneo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Niigata University
神経細胞死におけるリソゾ-ムシスティンプロテア-ゼの役割Principal Investigator
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Iwate Medical University
Localization of angiotensinogen and its mRNA in hepatocytes of adult and embryonic rats.Principal Investigator
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Tsukuba

[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23390041
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez2013
- Author(s)
  Uchiyama Y, Kominami E
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23659102
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23659102
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y, Kominami E
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23390041
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In : Lipid metabolism. (Ed by Rodrigo Valenzuela Baez)2013
- Author(s)
  Uchiyama Y, Kominami E
- Data Source
  KAKENHI-PROJECT-23390041
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y
- Publisher
  InTech
- Data Source
  KAKENHI-PLANNED-23111004
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y, Kominami E
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-25670099
[Book] Autophagy regulates lipid droplet formation and adipogenesis. In: Lipid metabolism. Ed by Rodrigo Valenzuela Baez.2013
- Author(s)
  Uchiyama Y, Kominami E
- Publisher
  InTech
- Data Source
  KAKENHI-PLANNED-23111004
[Book] Autophagy of the nervous sysytem (Ed by Zhenyu Yue and Charleen Chu)(World Scientific)2012
- Author(s)
  Komatsu M, Koike M, Ichimura Y, Uchiyama Y
- Total Pages
  464
- Publisher
  Genetic Mouse Models for Elucidation of Autophagy-Lysosomal Systems in Neurons Under Physiologic and Pathologic Condition
- Data Source
  KAKENHI-PLANNED-23111004
[Book] Autophagy of the nervous system (Ed by Zhenyu Yue and Charleen Chu) World Scientifc2012
- Author(s)
  Komatsu M, Koike M, Ichimura Y, Uchiyama Y
- Total Pages
  464
- Publisher
  Genetic Mouse Models for Elucidation of Autophagy-Lysosomal Systems in Neurons Under Physiologic and Pathologic Condition
- Data Source
  KAKENHI-PROJECT-23659102
[Book] 「リソソーム内の分解機構」オートファジー生命をささえる細胞の自己分解システム2012
- Author(s)
  小池正人、内山安男
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23659102
[Book] Autophagy of the nervous system World Scientifc(Ed by Zhenyu Yue and Charleen Chu)2012
- Author(s)
  Komatsu M, Koike M, Ichimura Y, Uchiyama Y
- Total Pages
  464
- Publisher
  Genetic Mouse Models for Elucidation of Autophagy-Lysosomal Systems in Neurons Under Physiologic and Pathologic Condition
- Data Source
  KAKENHI-PROJECT-23390041
[Book] Genetic mouse models for elucidation of autophagy-lysosomal systems in neurons under physiologic and pathologic conditions. In Ed. Zhenyu yue, Charleen T Chu: Autophagy of the nervous system -Cellular self-digestion in neurons and neurological diseases2012
- Author(s)
  Komatsu M, Koike M, Ichimura Y, Uchiyama Y
- Publisher
  World Scientific
- Data Source
  KAKENHI-PROJECT-23659102
[Book] Molecular imaging for integrated medical therapy and drug development(Eds. Nagara Tamaki and Yuji Kuge, Autophagy and cell death)2010
- Author(s)
  Uchiyama Y, Koike M, Shibata M
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-16GS0315
[Book] Methods Enzymol. Vol.453 (Autophagy in Disease and Clinical Applications, Part C)(Ed. Daniel J. Klionsky, Autophagic neuron death)2009
- Author(s)
  Uchiyama Y, Koike M, Shibata M, Sasaki M
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Suppression of ischemia-induced hippocampal pyramidal neuron death by hyaluronan tetrasaccharide through inhibition of toll-like receptor 2 signaling pathway.2016
- Author(s)
  Sunabori T, Koike M, Asari A, Oonuki Y, Uchiyama Y
- Journal Title
  
  Am J Pathol
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Cathepsin D in podocytes plays an important role in the pathogenesis of proteinuria and chronic kidney disease2016
- Author(s)
  Nonaka-Yamamoto K, Koike M, Asanuma K, Akiba-Takagi M,1 Trejo JAO, Seki T, Hidaka T, ◎Ichimura K, Sakai T, Tada N, Ueno T, Uchiyama Y, Tomino Y.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: in press Issue: 9 Pages: 2685-2700
- DOI
  10.1681/asn.2015040366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18960, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-26430207
[Journal Article] A specific tripeptidyl substrate for tripeptidyl peptidase activity is effectively hydrolyzed by alanyl aminopeptidase/aminopeptidase N/CD13 in the rat kidney 2016
- Author(s)
 Shibata, M., Koike, M., Kusumi, S., Sato, N., Uchiyama, Y
- Journal Title
 
 Archives of Histology and Cytology
 
 Volume: 76 Issue: 1 Pages: 1-8
- DOI
 10.1679/aohc.76.1
- NAID
 130005131324
- ISSN
 0914-9465, 1349-1717
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-23111004, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-25460276
[Journal Article] Property of Lysosomal Storage Disease associated with Midbrain Pathology in the CNS of LAMP-2-deficient Mice.2015
- Author(s)
  Furuta A, Kikuchi H, Fujita H, Yamada D, Fujiwara Y, Kabuta T, Nishino I, Wada K, Uchiyama Y
- Journal Title
  
  Am J Pathol
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition.2015
- Author(s)
  Nori S, Okada Y, Nishimura S, Ssaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H
- Journal Title
  
  Stem Cell Rep
  
  Volume: 4 Pages: 1-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi
- Journal Title
  
  PLoS Genetics
  
  Volume: 11 Issue: 4 Pages: 1-14
- DOI
  10.1371/journal.pgen.1005065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01682, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-25460276, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-26670442, KAKENHI-PROJECT-26860666, KAKENHI-PROJECT-15K19486, KAKENHI-PLANNED-23111002, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-15H02540, KAKENHI-PROJECT-25281019, KAKENHI-PROJECT-15H05713
[Journal Article] A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy.2015
- Author(s)
  Tanida I, Ueno T, Uchiyama Y
- Journal Title
  
  Pros ONE
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study.2015
- Author(s)
  Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Yuanzhe L, Ogaki K, Ando M, Yoshinon H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
- Journal Title
  
  Lancet Neurol
  
  Volume: 14 Issue: 3 Pages: 274-282
- DOI
  10.1016/s1474-4422(14)70266-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24500868, KAKENHI-PROJECT-24790903, KAKENHI-PUBLICLY-25110720, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10050, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-25257507, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25305030
[Journal Article] A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy.2015
- Author(s)
  Tanida I, Ueno T, Uchiyama Y
- Journal Title
  
  Pros ONE
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] EFA6A, a gunanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth2015
- Author(s)
  Fukaya M, Fukushima D, Hara Y, Sakagami H.
- Journal Title
  
  J. Neurochem.
  
  Volume: 4 Issue: 3 Pages: 360-73
- DOI
  10.1016/j.stemcr.2015.01.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-25110730, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25640038, KAKENHI-PUBLICLY-26111519, KAKENHI-PLANNED-26117007, KAKENHI-PLANNED-23111004
[Journal Article] A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy.2015
- Author(s)
  Tanida I, Ueno T, Uchiyama Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 10 Pages: e110600-e110600
- DOI
  10.1371/journal.pone.0110600
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Cellular localization and tissue distribution of endogenous DFCP1 protein.2015
- Author(s)
  Nanao T, Koike M, Yamaguchi J, Sasaki M, Uchiyama Y
- Journal Title
  
  Biomed Res
  
  Volume: 36 Pages: 121-133
- NAID
  130005065279
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Cellular localization and tissue distribution of endogenous DFCP1 protein 2015
- Author(s)
 Nanao T, Koike M, Yamaguchi J, Sasaki M, Uchiyama Y.
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 2 Pages: 121-133
- DOI
 10.2220/biomedres.36.121
- NAID
 130005065279
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-25460276, KAKENHI-PUBLICLY-26111519, KAKENHI-PLANNED-23111004
[Journal Article] Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils.2015
- Author(s)
  Rinchai D, Riyapa D, Buddhisa S, Utispan K, Titball RW, Stevens MP, Stevens JM, Ogawa M, Tanida I, Koike M, Uchiyama Y, Ato M, Lertmemongkolchai G.
- Journal Title
  
  Autophagy
  
  Volume: 11 Issue: 5 Pages: 748-755
- DOI
  10.1080/15548627.2015.1040969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12749, KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-23111004, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-25293227
[Journal Article] CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study2015
- Author(s)
  Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N
- Journal Title
  
  Lancet Neurol
  
  Volume: 14 Pages: 274-282
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Property of Lysosomal Storage Disease associated with Midbrain Pathology in the CNS of LAMP-2-deficient Mice.2015
- Author(s)
  Furuta A, Kikuchi H, Fujita H, Yamada D, Fujiwara Y, Kabuta T, Nishino I, Wada K, Uchiyama Y
- Journal Title
  
  Am J Pathol
  
  Volume: 185 Issue: 6 Pages: 1713-1723
- DOI
  10.1016/j.ajpath.2015.02.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-14J08223
[Journal Article] Axonal accumulation of alpha-synuclein in Gaucher disease model of medaka (Oryzias latipes) does not contribute to neurodegeneration.2015
- Author(s)
  Uemura N, Koike M, Ansai K, Kinoshita M, Fujiwara-Ishikawa T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R
- Journal Title
  
  Pros Genetics
  
  Volume: 11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.2014
- Author(s)
  Yokono, M., Takasu, T., Hayashizaki, Y., Mitsuoka, K., Kihara, R., Muramatsu, Y., Miyoshi, S., Tahara, A., Kurosaka, E., Li, Q., Tomiyama, H., Sasamata, M., Shibasaki, M., Uchiyama, Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 727 Pages: 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-Cre driver mice.2014
- Author(s)
  Sakata, K., Ohmuraya, M., Araki, K., Suzuki C, Ida S, Hashimoto D, Wang J, Uchiyama Y, Baba H, *Yamamura K
- Journal Title
  
  Exp Animals
  
  Volume: 63 Pages: 45-53
- NAID
  130003391605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.2014
- Author(s)
  Awazawa, M., Futami, T., Sakada, M., Kaneko, K., Ohsugi, M., Nakaya, K., Terai, A., Suzuki, R., Koike, M., Uchiyama, Y., Kadowaki, T., Ueki, K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.2014
- Author(s)
  Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y, Yoshida K
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Pages: 779-787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Increased immunoreactivity of cathepsins in the rat esophagus under chronic acid reflux esophagitis.2014
- Author(s)
  Suyama M, Koik M, Asaoka D, Mori H, Oguro M, Ueno T, Nagahara A, Watanabe S, Uchiyama Y
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 62 Pages: 645-660
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.2014
- Author(s)
  Awazawa M, Futami T, Sakada M, Kaneko K, Ohsugi M, Nakaya K, Terai A, Suzuki R, Koike M, Uchiyama Y, Kadowaki T, Ueki K
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34 Pages: 1290-1299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic impairment.2014
- Author(s)
  Bartolome A, Kimura-Koyanagi M, Asahara S, Guillén C, Teruyama K, Inoue H, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y
- Journal Title
  
  Diabetes
  
  Volume: 63 Pages: 2996-3008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.2014
- Author(s)
  Nakafuku-Fukuda M, Hirata T, Keto Y, Yamano M, Yokoyama T, Uchiyama Y
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 731 Pages: 88-92
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-Cre driver mice.2014
- Author(s)
  Sakata, K., Ohmuraya, M., Araki, K., Suzuki C, Ida S, Hashimoto D, Wang J, Uchiyama Y, Baba H, *Yamamura K
- Journal Title
  
  Exp Animals
  
  Volume: 63 Pages: 45-53
- NAID
  130003391605
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.2014
- Author(s)
  Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, Maity SN, Shimogori T, Hattori N, Nukina N
- Journal Title
  
  Nat Commun
  
  Volume: 5 Pages: 3354-3354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.2014
- Author(s)
  Awazawa, M., Futami, T., Sakada, M., Kaneko, K., Ohsugi, M., Nakaya, K., Terai, A., Suzuki, R., Koike, M., Uchiyama, Y., Kadowaki, T., Ueki, K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.2014
- Author(s)
  Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y, Yoshida K
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Pages: 779-787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.2014
- Author(s)
  Nakafuku-Fukuda, M., Hirata, T., Keto, Y., Yamano, M., Yokoyama, T., Uchiyama, Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-Cre driver mice.2014
- Author(s)
  Sakata, K., Ohmuraya, M., Araki, K., Suzuki C, Ida S, Hashimoto D, Wang J, Uchiyama Y, Baba H, *Yamamura K
- Journal Title
  
  Exp Animals
  
  Volume: 63 Pages: 45-53
- NAID
  130003391605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.2014
- Author(s)
  Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, Maity SN, Shimogori T, Hattori N, Nukina N
- Journal Title
  
  Nat Commun
  
  Volume: 5 Pages: 3354-3354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.2014
- Author(s)
  Nakafuku-Fukuda M, Hirata T, Keto Y, Yamano M, Yokoyama T, Uchiyama Y
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 731 Pages: 88-92
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Spatotemporal expression of TRPM4 in the mouse cochlea.2014
- Author(s)
  Sakuraba M, Murata J, Teruyama R, Kamiya K, Yamaguchi J, Okano Y, Uchiyama Y, Ikeda K
- Journal Title
  
  J Neurosci Res
  
  Volume: 92 Pages: 1409-1418
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.2014
- Author(s)
  Awazawa, M., Futami, T., Sakada, M., Kaneko, K., Ohsugi, M., Nakaya, K., Terai, A., Suzuki, R., Koike, M., Uchiyama, Y., Kadowaki, T., Ueki, K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Spatotemporal expression of TRPM4 in the mouse cochlea.2014
- Author(s)
  Sakuraba M, Murata J, Teruyama R, Kamiya K, Yamaguchi J, Okano Y, Uchiyama Y, Ikeda K
- Journal Title
  
  J Neurosci Res
  
  Volume: 92 Pages: 1409-1418
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.2014
- Author(s)
  Yokono M, Takasu T, Hayashizaki Y, Mitsuoka K, Kihara R, Muramatsu Y, Miyoshi S, Tahara A, Kurosaki E, Li Q, Tomiyama H, Sasamata M, Shibasaki M, Uchiyama Y
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 727 Pages: 66-74
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.2014
- Author(s)
  Nakafuku-Fukuda, M., Hirata, T., Keto, Y., Yamano, M., Yokoyama, T., Uchiyama, Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.2014
- Author(s)
  Yamanaka, T., Tosaki, A., Kurosawa, M., Matsumoto, G., Koike, M., Uchiyama, Y., Maity, S.N., Shimogori, T., Hattori, N., *Nukina, N.
- Journal Title
  
  Nat Commun
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Nirtic oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia.2014
- Author(s)
  Ueshima　S, Nishida T, Koike M, Matsuda H, Sawa Y, Uchiyama Y
- Journal Title
  
  Biomed Res
  
  Volume: 35 Pages: 251-262
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus.2014
- Author(s)
  Awazawa M, Futami T, Sakada M, Kaneko K, Ohsugi M, Nakaya K, Terai A, Suzuki R, Koike M, Uchiyama Y, Kadowaki T, Ueki K
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34 Pages: 1290-1299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.2014
- Author(s)
  Yamanaka, T., Tosaki, A., Kurosawa, M., Matsumoto, G., Koike, M., Uchiyama, Y., Maity, S.N., Shimogori, T., Hattori, N., *Nukina, N.
- Journal Title
  
  Nat Commun
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Nirtic oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia.2014
- Author(s)
  Ueshima　S, Nishida T, Koike M, Matsuda H, Sawa Y, Uchiyama Y
- Journal Title
  
  Biomed Res
  
  Volume: 35 Pages: 251-262
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Increased immunoreactivity of cathepsins in the rat esophagus under chronic acid reflux esophagitis.2014
- Author(s)
  Suyama M, Koik M, Asaoka D, Mori H, Oguro M, Ueno T, Nagahara A, Watanabe S, Uchiyama U
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 62 Pages: 645-660
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic impairment.2014
- Author(s)
  Bartolome A, Kimura-Koyanagi M, Asahara S, Guillén C, Teruyama K, Inoue H, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y
- Journal Title
  
  Diabetes
  
  Volume: 63 Pages: 2996-3008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization.2014
- Author(s)
  Yamanaka, T., Tosaki, A., Kurosawa, M., Matsumoto, G., Koike, M., Uchiyama, Y., Maity, S.N., Shimogori, T., Hattori, N., *Nukina, N.
- Journal Title
  
  Nat Commun
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.2014
- Author(s)
  Yokono M, Takasu T, Hayashizaki Y, Mitsuoka K, Kihara R, Muramatsu Y, Miyoshi S, Tahara A, Kurosaki E, Li Q, Tomiyama H, Sasamata M, Shibasaki M, Uchiyama Y
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 727 Pages: 66-74
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Inhibitory effect of the selective secretion 5-HT receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.2014
- Author(s)
  Nakafuku-Fukuda, M., Hirata, T., Keto, Y., Yamano, M., Yokoyama, T., Uchiyama, Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons2013
- Author(s)
  Matsui, H.*, Sato, F.*, Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., Takahashi, R.
- Journal Title
  
  FEBS letters
  
  Volume: 587(9) Pages: 1316-25
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.2013
- Author(s)
  Kashima, J., Shintani-Ishida, K., Nakajima, M., Maeda, H., Unuma, K., Uchiyama, Y., *Yoshida, K.
- Journal Title
  
  Hepatology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous systems.2013
- Author(s)
  Koike, M., Shibata, M., Ezaki, J., Peters, C., Saftig, P., Kominami, E., Uchiyama, Y.
- Journal Title
  
  Eur J Neurosci
  
  Volume: 37 Pages: 816-830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Particle size of latex beads dictates IL-1 production mechanism.2013
- Author(s)
  Adachi, T., Takahara, K., Taneo, J., Uchiyama, Y., *Inaba, K.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous systems.2013
- Author(s)
  Koike, M., Shibata, M., Ezaki, J., Peters, C., Saftig, P., Kominami, E., Uchiyama, Y.
- Journal Title
  
  Eur J Neurosci
  
  Volume: 37 Pages: 816-830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous systems.2013
- Author(s)
  Koike, M., Shibata, M., Ezaki, J., Peters, C., Saftig, P., Kominami, E., Uchiyama, Y.
- Journal Title
  
  Eur J Neurosci
  
  Volume: 37 Pages: 816-830
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.2013
- Author(s)
  Koike, M., *Tanida, I., Nanao, N., Tada, N., Iwata, J., Ueno, T., Kominami, E., *Uchiyama, Y.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.2013
- Author(s)
  Matsui, H., #Sato, F., Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., *Takahashi, R.
- Journal Title
  
  FEBS letters
  
  Volume: 9 Pages: 1316-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.2013
- Author(s)
  Koike, M., Tanida, I., Nanao, N., Tada, N., Iwata, J., Ueno, T., Kominami, E., *Uchiyama, Y.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease.2013
- Author(s)
  Furuta, A., Wakabayashi, K., Haratake, J., Kikuchi, H., Kabuta, T., Mori, F., Tokonami, F., Katsumi, Y., Tanioka, F., Uchiyama, Y., Nishino, I., Wada, K.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 125 Pages: 459-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Particle size of latex beads dictates IL-1 production mechanism.2013
- Author(s)
  Adachi, T., Takahara, K., Taneo, J., Uchiyama, Y., *Inaba, K.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Biogenesis and proteolytic processing of lysosomal DNase II.2013
- Author(s)
  Ohkouchi S, Shibata M, Sasaki M, Koike M, Safig P, Peters C, Nagata S, *Uchiyama Y
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Biogenesis and proteolytic processing of lysosomal DNase II2013
- Author(s)
  Ohkouchi, S., Shibata, M., Sasaki, M., Koike, M., Saftig, P., Peters, C., Nagata, S., Uchiyama, Y
- Journal Title
  
  PLoS One
  
  Volume: 8(3)
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease2013
- Author(s)
  Furuta, A., Wakabayashi, K., Haratake, J., Kikuchi, H., Kabuta, T., Mori, F., Tokonami, F., Katsumi, Y., Tanioka, F., Uchiyama, Y., Nishino, I., Wada, K..
- Journal Title
  
  Acta Neuropathol
  
  Volume: 125(3) Pages: 459-461
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Exendin-4 improves beta cell function in autophagy-deficient beta cells.2013
- Author(s)
  Abe, H., Uchida, T., Hara, A., Mizukami, H., Komiya, K., Koike, M., Shigihara, N., Toyofuku, Y., Ogihara, T., Uchiyama, Y., Yagihashi, S., Fujitani, Y., Watada, H.
- Journal Title
  
  Endicrinology
  
  Volume: 154 Pages: 4512-4524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons2013
- Author(s)
  Koike, M.*, Tanida, I.*, Nanao, T., Tada, N., Iwata, J., Ueno, T., Kominami, E., Uchiyama, Y
- Journal Title
  
  PLoS One
  
  Volume: 8(5)
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.2013
- Author(s)
  Nonomura, K., Yamaguchi, Y., Hamachi, M., Koike, M., Uchiyama, Y., Nakazato, K., Mochizuki, A., Sakaue-Sawano, A., Miyawaki, A., Yoshida, H., Kuida, K., *Miura, M.
- Journal Title
  
  Dev Cell
  
  Volume: 27 Pages: 621-634
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease.2013
- Author(s)
  Furuta, A., Wakabayashi, K., Haratake, J., Kikuchi, H., Kabuta, T., Mori, F., Tokonami, F., Katsumi, Y., Tanioka, F., Uchiyama, Y., Nishino, I., Wada, K.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 125 Pages: 459-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease.2013
- Author(s)
  Furuta, A., Wakabayashi, K., Haratake, J., Kikuchi, H., Kabuta, T., Mori, F., Tokonami, F., Katsumi, Y., Tanioka, F., Uchiyama, Y., Nishino, I., Wada, K.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 125 Pages: 459-461
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons.2013
- Author(s)
  Koike, M., *Tanida, I., Nanao, N., Tada, N., Iwata, J., Ueno, T., Kominami, E., *Uchiyama, Y.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Biogenesis and proteolytic processing of lysosomal DNase II.2013
- Author(s)
  Ohkouchi S, Shibata M, Sasaki M, Koike M, Safig P, Peters C, Nagata S, *Uchiyama Y
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.2013
- Author(s)
  Matsui, H., Sato, F., Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., *Takahashi, R.
- Journal Title
  
  FEBS letters
  
  Volume: 9 Pages: 1316-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Exendin-4 improves beta cell function in autophagy-deficient beta cells.2013
- Author(s)
  Abe, H., Uchida, T., Hara, A., Mizukami, H., Komiya, K., Koike, M., Shigihara, N., Toyofuku, Y., Ogihara, T., Uchiyama, Y., Yagihashi, S., Fujitani, Y., Watada, H.
- Journal Title
  
  Endicrinology
  
  Volume: 154 Pages: 4512-4524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Biogenesis and proteolytic processing of lysosomal DNase II.2013
- Author(s)
  Ohkouchi S, Shibata M, Sasaki M, Koike M, Safig P, Peters C, Nagata S, *Uchiyama Y
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.2013
- Author(s)
  Kashima, J., Shintani-Ishida, K., Nakajima, M., Maeda, H., Unuma, K., Uchiyama, Y., *Yoshida, K.
- Journal Title
  
  Hepatology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Exendin-4 improves beta cell function in autophagy-deficient beta cells.2013
- Author(s)
  Abe, H., Uchida, T., Hara, A., Mizukami, H., Komiya, K., Koike, M., Shigihara, N., Toyofuku, Y., Ogihara, T., Uchiyama, Y., Yagihashi, S., Fujitani, Y., Watada, H.
- Journal Title
  
  Endicrinology
  
  Volume: 154 Pages: 4512-4524
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.2013
- Author(s)
  Nonomura, K., Yamaguchi, Y., Hamachi, M., Koike, M., Uchiyama, Y., Nakazato, K., Mochizuki, A., Sakaue-Sawano, A., Miyawaki, A., Yoshida, H., Kuida, K., *Miura, M.
- Journal Title
  
  Dev Cell
  
  Volume: 27 Pages: 621-634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.2013
- Author(s)
  Matsui, H., Sato, F., Sato, S., Koike, M., Taruno, Y., Saiki, S., Funayama, M., Ito, H., Taniguchi, Y., Uemura, N., Toyoda, A., Sakaki, Y., Takeda, S., Uchiyama, Y., Hattori, N., *Takahashi, R.
- Journal Title
  
  FEBS letters 587
  
  Volume: 9 Pages: 1316-25
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.2013
- Author(s)
  Okura, H., Kobayashi, T., Koike, M., Ohsawa, M., Zhang, D., Arai, H., Uchiyama, Y., *Hino O
- Journal Title
  
  Int J Oncol
  
  Volume: 43 Issue: 2 Pages: 447-456
- DOI
  10.3892/ijo.2013.1984
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-23390041, KAKENHI-PROJECT-23659206, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25670099, KAKENHI-PROJECT-25670196
[Journal Article] Immunocytochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.2013
- Author(s)
  Kashima, J., Shintani-Ishida, K., Nakajima, M., Maeda, H., Unuma, K., Uchiyama, Y., *Yoshida, K.
- Journal Title
  
  Hepatology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions2013
- Author(s)
  Hayakawa, N., Shiozaki, M., Shibata, M., Koike, M., Uchiyama, Y., Gotow, T.
- Journal Title
  
  Eur. J. Cell Biol
  
  Volume: 92(1) Pages: 30-43
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Particle size of latex beads dictates IL-1 production mechanism.2013
- Author(s)
  Adachi, T., Takahara, K., Taneo, J., Uchiyama, Y., *Inaba, K.
- Journal Title
  
  PLos One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670099
[Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.2013
- Author(s)
  Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, Takahashi R.
- Journal Title
  
  FEBS Lett
  
  Volume: 587(9) Issue: 9 Pages: 1316-1325
- DOI
  10.1016/j.febslet.2013.02.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23590244, KAKENHI-PROJECT-23689046, KAKENHI-PROJECT-23790238, KAKENHI-PROJECT-24300132, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24659435, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PUBLICLY-23129506
[Journal Article] Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous systems2013
- Author(s)
  Koike, M., Shibata, M., Ezaki, J., Peters, C., Saftig, P., Kominami, E., Uchiyama, Y.
- Journal Title
  
  Eur. J. Neurosci.
  
  Volume: 37(5) Pages: 816-20
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.2013
- Author(s)
  Nonomura, K., Yamaguchi, Y., Hamachi, M., Koike, M., Uchiyama, Y., Nakazato, K., Mochizuki, A., Sakaue-Sawano, A., Miyawaki, A., Yoshida, H., Kuida, K., *Miura, M.
- Journal Title
  
  Dev Cell
  
  Volume: 27 Pages: 621-634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] 神経性セロイドリポフスチン蓄積症における"異常なリソソーム"のオートファジーによる処理2012
- Author(s)
  小池正人、内山安男
- Journal Title
  
  生体の科学
  
  Volume: 63(5) Pages: 404-5
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] The development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA62012
- Author(s)
  Unno, T., Wakamori, M., Koike, M., Uchiyama, Y., Ishikawa, K., Kubota, H., Yoshida, T., Sasakawa, H., Peters, C., Mizusawa, H., Watase, K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109(43) Pages: 17693-8
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM52012
- Author(s)
  Sekine, S., Kanamaru, Y., Koike, M., Nishihara, A., Okada, M., Kinoshita, H., Kamiyama, M., Maruyama, J., Uchiyama, Y., Ishihara, N., Takeda, K., Ichijo, H.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287(41) Pages: 34635-45
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Mitochondrial dysfunction with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain2012
- Author(s)
  Imaizumi, Y., Okada, Y., Akamatsu, W., Koike, M., Kuzumaki, N., Hayakawa, H., Nihira, T., Kobayashi, T., Ohyama, M., Sato, S., Takanashi, M., Funayama, M., Hirayama, A., Soga, T., Hishiki, T., Suematsu, M., Yagi, T., Ito, D., Kosakai, A., Hayashi, K., Shouji, M., Nakanishi, A., Suzuki, N., Mizuno, Y., Mizushima, N., Amagai, M., Uchiyama, Y., Mochizuki, H., Hattori, N., Okano, H.
- Journal Title
  
  Molecular Brain
  
  Volume: 5(1) Pages: 35-35
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.2012
- Author(s)
  Tashiro Y.*, Urushitani, M.*, Inoue, H., Koike, M., Uchiyama, Y., Komatsu, M., Tanaka, K., Yamazaki, M., Abe, M., Misawa, H., Sakimura, K., Ito, H., Takahashi, R
- Journal Title
  
  J. Biol. Chem
  
  Volume: 109(43) Pages: 42984-94
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis2012
- Author(s)
  Piao, X., Komazawa-Sakon, S., Nishida, T., Koike, M., Piao JH., Ehlken, H., Kurihara, H., Hara, M., van Rooijen, N., Schutz, G., Ohmuraya, M., Uchiyama, Y., Yagita, H., Okumura, K., He YW., Nakano, H.
- Journal Title
  
  Sci. Signal
  
  Volume: 5(255)
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] リソソームプロテアーゼの多様性とその病態生理学的役割2011
- Author(s)
  小池正人、内山安男
- Journal Title
  
  実験医学増刊号
  
  Volume: 29 Pages: 1903-1908
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] 脂肪滴とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 30 Pages: 338-343
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] リソソームプロテアーゼの多様性とその病態生理学的役割2011
- Author(s)
  小池正人、内山安男
- Journal Title
  
  実験医学増感号
  
  Volume: 29 Pages: 1903-1908
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] RNAi法を利用した抗体の評価2011
- Author(s)
  柴田昌宏、内山安男
- Journal Title
  
  生体の科学
  
  Volume: 63 Pages: 98-103
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] 虚血性細胞死とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  神経内科
  
  Volume: 75 Pages: 169-175
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.2011
- Author(s)
  Shiozaki M, Hayakawa N, Shibata M, Koike M, Uchiyama Y, Gotow T
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 136 Pages: 475-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] 虚血性細胞死とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  神経内科
  
  Volume: 75 Pages: 169-175
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC12011
- Author(s)
  Koyanagi, M., Asahara, S., Matsuda, T., Hashimoto, N., Shigeyama, Y., Shibutani, Y., Kanno, A., Fuchita, M., Mikami, T., Hosooka, T., Inoue, H., Matsumoto, M., Koike, M., Uchiyama, Y., Noda, T., Seino, S., Kasuga, M., Kido, Y.
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.Histochem.2011
- Author(s)
  Shiozaki, M., Hayakawa, N., Shibata, M., Koike, M., Uchiyama, Y., Gotow, T.
- Journal Title
  
  Cell Biol
  
  Volume: 136(4) Pages: 475-89
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Kuwahara, Y., Oikawa, T., Ochiai, Y., Roudkenar, M.H., Fukumoto, M., Shimura, T., Ohtake, Y., Ohkubo, Y., Mori, S., Uchiyama, Y., Fukumoto, M.2011
- Author(s)
  Kuwahara, Y., Oikawa, T., Ochiai, Y., Roudkenar, M.H., Fukumoto, M., Shimura, T., Ohtake, Y., Ohkubo, Y., Mori, S., Uchiyama, Y., Fukumoto, M.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 2(6)
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy2011
- Author(s)
  Kuwahara Y, Oikawa T, Ochiai Y, Roudkenar, M Fukumoto, T Shimura, Y Ohtake M H, Ohkubo Y, Mori S, Uchiyama Y, Fukumoto M
- Journal Title
  
  Cell Death Dis (2011)
  
  Volume: 2 Issue: 6 Pages: e177-e177
- DOI
  10.1038/cddis.2011.56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659431, KAKENHI-PROJECT-22390378, KAKENHI-PROJECT-22659363, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-23390041, KAKENHI-PROJECT-23659102, KAKENHI-PROJECT-23659197, KAKENHI-PROJECT-23710066
[Journal Article] Grafted human induced pluripotent stem cell-derived neurospheres promotes motor functional recovery after spinal cord injury in mice.2011
- Author(s)
  Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108 Pages: 16825-16830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease.2011
- Author(s)
  Oguro M, Koike M, Ueno T, Asaoka D, Mori H, Nagahara A, Uchiyama Y, Watanabe S
- Journal Title
  
  J Gastroenterol.
  
  Volume: 46 Pages: 629-638
- NAID
  10029029126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.2011
- Author(s)
  Koyanagi M, Asahara A, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Hosooka T, Inoue H, Matsumoto H, Koike M, Uchiyama Y, NodaT, Seino S, Kasuga M, Kido Y
- Journal Title
  
  PLosOne
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] リソソームプロテアーゼの多様性とその病態生理学的役割2011
- Author(s)
  小池正人、内山安男
- Journal Title
  
  実験医学増刊号
  
  Volume: 29 Pages: 1903-1908
- Data Source
  KAKENHI-PLANNED-23111004
[Journal Article] 虚血性細胞死とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  神経内科
  
  Volume: 75(2) Pages: 169-175
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Grafted human induced pluripotent stem-cell-derived neurospheres promotes motor functional recovery after spinal cord injury in mice.2011
- Author(s)
  Nori, S., Okada, Y., Yasuda, A., Tsuji, O., Takahashi, Y., Kobayashi, Y., Fujiyoshi, K., Koike, M., Uchiyama, Y., Ikeda, E., Toyama, Y., Yamanaka, S., Nakamura, M., Okano, H
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108(40) Pages: 16825-30
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes2011
- Author(s)
  Uchida, Y., Hasegawa, J., Chinnapen, D., Inoue, T., Okazaki, S., Kato, R., Wakatsuki, S., Misaki, R., Koike, M., Uchiyama, Y., Iemura, S., Natsume, T., Kuwahara, R., Nakagawa, T., Nishikawa, K., Mukai, K., Miyoshi, E., Taniguchi, N., Sheff, D., Lencer, W.I., Taguchi, T., Arai H
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108(38) Pages: 15846-51
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] リソソームプロテアーゼの多様性とその病態生理学的役割2011
- Author(s)
  内山安男、小池正人
- Journal Title
  
  実験医学増刊号
  
  Volume: 29(12) Pages: 1903-1908
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] 脂肪的とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 30 Pages: 338-343
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] 脂肪滴とオートファジー2011
- Author(s)
  内山安男
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 33(4) Pages: 338-343
- Data Source
  KAKENHI-PROJECT-23390041
[Journal Article] Chondrogenesis during the ES cell differentiation in vitro.2010
- Author(s)
  Yagita Y, HorieK, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y
- Journal Title
  
  PNAS 107
  
  Pages: 3846-3851
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Chondrogenesis during the ES cell differentiation in vitro.2010
- Author(s)
  Yagita Y, Horie K, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y
- Journal Title
  
  PNAS
  
  Volume: 107 Pages: 3846-3851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains2010
- Author(s)
  Tamura H, Shibata M, Koike M, Sasaki M, Uchiyama Y
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 58 Pages: 443-453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation2010
- Author(s)
  Shibata M, Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y
- Journal Title
  
  Biophys Biochem Res Comm 393
  
  Pages: 274-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains2010
- Author(s)
  Tamura H, Shibata M, Koike M, Sasaki M, Uchiyama Y
- Journal Title
  
  J Histochem Cytochem
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.2010
- Author(s)
  Lee J-H, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA
- Journal Title
  
  Cell
  
  Volume: 141 Pages: 1146-1158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1^<H46R>-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking.2010
- Author(s)
 Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya A, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda JE
- Journal Title
 
 PLoS One
 
 Volume: 5
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21659050
[Journal Article] LC3, a microtubule-associated proteinlA/B light chain3, is involved in cytoplasmic lipid droplet formation2010
- Author(s)
  Shibata M, Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y
- Journal Title
  
  Biophys Biochem Res Comm 393
  
  Pages: 274-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] JE Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1^<H46R>-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking2010
- Author(s)
 Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya A, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda
- Journal Title
 
 PLoSONE (in press)
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21659050
[Journal Article] Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.2010
- Author(s)
  Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J, Yoshida T, Sato T, Peters C, Mochizuki M, Morita I
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Pages: 2571-2580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.2010
- Author(s)
  Tizon B, Sahoo S, Yu H, Gauthier S, Kumar AR, Mohan P, Figliola M, Pawlik M, Grubb A, Uchiyama Y, Bandyopadhyay U, Cuervo AM, Nixon RA, Levy E.
- Journal Title
  
  ProS One
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization2010
- Author(s)
  Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J, Yoshida T, Sato T, Peters C, Mochizuki M, Morita I
- Journal Title
  
  Am J Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] LC3, a microtubule-associated proteinlA/B light chain3, is involved in cytoplasmic lipid droplet formation.2010
- Author(s)
  Shibata Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y
- Journal Title
  
  BBRC 393
  
  Pages: 274-279
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Chondrogenesis during the ES cell differentiation in vitro2010
- Author(s)
  Yagita Y, Horie K, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y
- Journal Title
  
  PNAS 107
  
  Pages: 3846-3851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Chondrogenesis during the ES cell differentiation in vitro2010
- Author(s)
  Yagita Y, Horie K, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y
- Journal Title
  
  PNAS 107
  
  Pages: 3846-3851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.2010
- Author(s)
  Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume: 399 Pages: 391-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Involvement of cathepsin B in the processing and secretion of interleukin-1 in chromogranin A-stimulated microglial.2010
- Author(s)
  Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H
- Journal Title
  
  Glia
  
  Volume: 10.1002 Pages: 20906-20906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation.2010
- Author(s)
  Shibata M, Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y
- Journal Title
  
  Biophys Biochem Res Comm
  
  Volume: 393 Pages: 274-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains.2010
- Author(s)
  Tamura H, Shibata M, Koike M, Sasaki M, Uchiyama Y
- Journal Title
  
  J Histochem Cytochem 58
  
  Pages: 443-453
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Phosphorylation of highly conserved NF-M KSP repeats is not required for myelin-dependent radial axonal growth2009
- Author(s)
  Garcia M, Rao M, Fujimoto J, Garcia V, Shah S, Crum J, Gotow T, Uchiyama Y, Ellisman MH, Calcutt N, Cleveland D
- Journal Title
  
  J Nurosci 29
  
  Pages: 1277-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation.2009
- Author(s)
  Gotoh K, Lu Z, Morita M, Shibata M, Koike M, Waguri S, Dono K, Doki Y, Kominami E, Sugioka A, Monden M, Uchiyama Y
- Journal Title
  
  Autophagy 5
  
  Pages: 351-360
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Ablation of C/EBP beta alleviates ER stress and pancreatic beta cell failure through induction of GRP782009
- Author(s)
  Matsuda, T., Kido, Y., Nakano-Hashimoto, N., Kaisho, T., Tanaka, T., Asahara, S., Shigeyama, Y., Takeda, A., Inoue, T., Shibutani, Y., Koyanagi, M., Hosooka, T., Matsumoto, M., Inoue, H., Uchida, T., Koike, M., Uchiyama, Y., Akira, S., Kasuga, M.
- Journal Title
  
  J Clin Invest 120
  
  Pages: 115-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The MAP1-LC3 conjugation system is involved in lipid droplet formation.2009
- Author(s)
  Shibata M*, Yoshimura K*, Furuya M, Koike M, Ueno T, Komatsu M, Arai H, Tanaka K, Kominami E, Uchiyama Y
- Journal Title
  
  BBRC 382
  
  Pages: 419-423
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The MAP1-LC3 conjugation system is involved in lipid droplet formation2009
- Author(s)
  Shibata M*, Yoshimura K*, Furuya M, Koike M, Ueno T, Komatsu M, Arai H, Tanaka K, Kominami E, Uchiyama Y(*equally contributed)
- Journal Title
  
  Biophys Biochem Res Comm 382
  
  Pages: 419-423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb2009
- Author(s)
  Ohsawa S, Hamada S, Asou H, Kuida K, Uchiyama Y, Yoshida H, Miura M.
- Journal Title
  
  J Neurosci 29
  
  Pages: 11385-11292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article]2009
- Author(s)
  Uchiyama Y, Koike M, Shibata M
- Journal Title
  
  Autophagy and cell death. In : Molecular imaging for integrated medical therapy and drug development(Ed.Yuji Kuge)(Springer Japan)
  
  Pages: 176-188
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation2009
- Author(s)
  Gotoh K, Lu Z, Morita M, Shibata M, Koike M, Waguri S, DonoK, DokiY, Kominami E, Sugioka A, Monden M, Uchiyama Y
- Journal Title
  
  Autophagy 5
  
  Pages: 351-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Mini Screening of Kinase Inhibitors Affecting Period-length of Mammalian Cellular Circadian Clock2009
- Author(s)
  Yagita K, Yamanaka I, Koinuma S, Shigeyoshi Y, Uchiyama Y
- Journal Title
  
  Acta Histochem Cytochem 42
  
  Pages: 89-93
- NAID
  130000118206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The MAP1-LC3 conjugation system is involved in lipid droplet formation2009
- Author(s)
  Shibata M^*, Yoshimura K^*, Furuya M, Koike M, Ueno T, Komatsu M, Arai H, Tanaka K, Kominami E, Uchiyama Y(^* equally contributed)
- Journal Title
  
  Biophys Biochem Res Comm 382
  
  Pages: 419-423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Nesfatin-1-regulated paraventricular oxytocinergic signaling causes anorexia through a leptin-independent melanocortin pathway2009
- Author(s)
  Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
- Journal Title
  
  Cell Metabolism 10
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions2009
- Author(s)
  Sugita S, Horie S, Nakamura O, Maruyama K, Takase H, Usui Y, Takeuchi M, Ishidoh K, Koike M, Uchiyama Y, Peters C, Yamamoto Y, Mochizuki M.
- Journal Title
  
  J Immunol 183
  
  Pages: 5013-5022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Phosphorylation of highly conserved NF-M KSP repeats is not required for myelin-dependent radial axonal growth2009
- Author(s)
  Garcia M, Rao M, Fujimoto J, Garcia V, Shah S, Crum J, Gotow T, Uchiyama Y, Ellisman MH, Calcutt N, Cleveland D
- Journal Title
  
  J Nurosci 29
  
  Pages: 1277-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions2009
- Author(s)
  Sugita S, Horie S, Nakamura O, Maruyama K, Takase H, Usui Y, Takeuchi M, Ishidoh K, Koike M, Uchiyama Y, Peters C, Yamamoto Y, Mochizuki M.
- Journal Title
  
  J Immunol 183
  
  Pages: 5013-5022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation2009
- Author(s)
  Gotoh K, Lu Z, Morita M, Shibata M, Koike M, Waguri S, DonoK, DokiY, Kominami E, Sugioka A, Monden M, Uchiyama Y
- Journal Title
  
  Autophagy 5
  
  Pages: 351-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes2009
- Author(s)
  Nada S^*, Hondo A^*, Kasai A^*, Koike M^*, Saito K, Uchiyama Y, Okada M(^*equally contri buted)
- Journal Title
  
  EMBO J 28
  
  Pages: 477-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Mini Screening of Kinase Inhibitors Affecting Period-length of Mammalian Cellular Circadian Clock2009
- Author(s)
  Yagita K, Yamanaka I, Koinuma S, Shigeyoshi Y, Uchiyama Y.
- Journal Title
  
  Acta Histochem Cytochem 42
  
  Pages: 89-93
- NAID
  130000118206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article]2009
- Author(s)
  Uchiyama Y, Koike M, Shibata M, Sasaki M
- Journal Title
  
  Chapter 3 Autophagic neuron death. In : Autophagy in Disease and Clinical Applications, Part C Vol.453(Edited by : Daniel J.Klionsky)(Elsevier Inc.)
  
  Pages: 33-51
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Nesfatin-1-regulated paraventricular oxytocinergic signaling causes anorexia through a leptin-independent melanocortin pathway2009
- Author(s)
  Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
- Journal Title
  
  Cell Metabolism 10
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Ablation of C/EBP beta alleviates ER stress and pancreatic beta cell failure through induction of GRP782009
- Author(s)
  Matsuda, T., Kido, Y., Nakano-Hashimoto, N., Kaisho, T., Tanaka, T., Asahara, S., Shigeyama, Y., Takeda, A., Inoue, T., Shibutani, Y., Koyanagi, M., Hosooka, T., Matsumoto, M., Inoue, H., Uchida, T., Koike, M., Uchiyama, Y., Akira, S., Kasuga, M.
- Journal Title
  
  J Clin Invest 120
  
  Pages: 115-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats2009
- Author(s)
  Miyamoto K, Shiozaki M, Shibaita M, Koike M, Uchiyama Y, Gotow T
- Journal Title
  
  J Neurosci Res 87
  
  Pages: 556-566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.2009
- Author(s)
  Nada S*, Hondo A*, Kasai A*, Koike M*, Saito K, Uchiyama Y, Okada M
- Journal Title
  
  EMBO J 28
  
  Pages: 477-489
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes2009
- Author(s)
  Nada S*, Hondo A*, Kasai A*, Koike M*, Saito K, Uchiyama Y, Okada M(*equally contributed)
- Journal Title
  
  EMBO J 28
  
  Pages: 477-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article] Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats2009
- Author(s)
  Miyamoto K, Shiozaki M, Shibata M, Koike M, Uchiyama Y, Gotow T
- Journal Title
  
  J Neurosci Res 87
  
  Pages: 556-566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659050
[Journal Article]2009
- Author(s)
  Uchiyama Y, et al.
- Journal Title
  
  Autophagy and cell death. In : Molecular imaging for integrated medical therapy and drug development.( Ed.YujiKuge)(Springer Japan)
  
  Pages: 176-188
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article]2009
- Author(s)
  Uchiyama Y, et al.
- Journal Title
  
  Chapter 3 Autophagic neuron death. In : Autophagy in Disease and Clinical Applications, Part C (Edited by : Daniel J.Rlionsky Vol.453)(Elsevier Inc.)
  
  Pages: 33-51
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb2009
- Author(s)
  Ohsawa S, Hamada S, Asou H, Kuida K, Uchiyama Y, Yoshida H, Miura M.
- Journal Title
  
  J Neurosci 29
  
  Pages: 11385-11292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagy-Physiology and Pathophysiology.2008
- Author(s)
  Uchiyama Shibata M, Koike M, Yoshimura K, Sasaki M
- Journal Title
  
  Histochem Cell Biol 129
  
  Pages: 407-420
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Human RME-8 is involved in membrane trafficking through early endosomes2008
- Author(s)
  Fujibayashi A, Taguchi T, Misaki R, Ohtani M, Dohmae N, Takio K, Yamada M, Gu J, Yamakami M, Fukuda M, Waguri S, Uchiyama Y, Yoshimori T, Sekiguchi K
- Journal Title
  
  Cell Struct Funct 33
  
  Pages: 35-50
- NAID
  130004053865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagic neuron death in neonatal brain ischemia/hypoxia2008
- Author(s)
  Uchiyama, Y., Koike, M., Shibata, M.
- Journal Title
  
  Autophagy 4
  
  Pages: 404-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility2008
- Author(s)
  Takatsuka A, Yagi R, Koike M, Oneyama C, Nada S, Schmedt C, Uchiyama Y, Okada M
- Journal Title
  
  Dev Biol 315
  
  Pages: 474-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.2008
- Author(s)
  Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, Zhu C
- Journal Title
  
  J Neurosci 28
  
  Pages: 1490-1497
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in renal ischemia/reperfusion injury2008
- Author(s)
  Suzuki C, Takabatake Y, Tanaka H, Koike M, Shibata M, Uchiyama Y, Takahara S, Imai E, Isaka Y
- Journal Title
  
  Biochem Biophys Res Comm 368
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Human herpesvirus-6 induces MVB formation and virus egress occurs via an exosomal release pathway2008
- Author(s)
  Mori Y^*, Koike M^*, Moriishi E, Kawabata A, Tang H, Oyaizu H, Uchiyama Y, Yamanishi K^*equal contributors
- Journal Title
  
  Traffic 9
  
  Pages: 1728-1742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagy Physiology and Pathophysiology.2008
- Author(s)
  Uchiyama, Y.
- Journal Title
  
  Histochem Cell Biol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Human herpesvirus-6 induces MVB formation and virus egress occurs via an exosomal release pathway.2008
- Author(s)
  Mori Y*, Koike M*, Moriishi E, Kawabata A, Tang H, Oyaizu H, Uchiyama Y, Yamanishi K
- Journal Title
  
  Traffic 9
  
  Pages: 1728-1742
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury.2008
- Author(s)
  Koike M, Shibata S, Tadakoshi T, Gotoh K, Komatsu M, Waguri S, KawaharaN, Kuida K, Nagata S, Kominami E, Tanaka K, Uchiyama Y
- Journal Title
  
  Am J Pathol 172
  
  Pages: 454-469
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity2008
- Author(s)
  Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie Z-L, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, Zhou Y, Peng L, Lu YM, Standaert DG, Walls KC, Shacka JJ, Roth KA, Zhang J
- Journal Title
  
  Mol Brain 1
  
  Pages: 17-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse2008
- Author(s)
  Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T
- Journal Title
  
  Mol Cell Neurosci 38
  
  Pages: 66-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Morphological and biochemical signs of age-related neurodegenerative changes in Klotho mutant mice2008
- Author(s)
  Shiozaki M, Yoshimura K, Shibata M, Koike M, Uchiyama Y, Gotow T
- Journal Title
  
  Neurcience 152
  
  Pages: 924-941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice2008
- Author(s)
  Sou YS, Waguri S, Iwata JI, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanaka K, Komatsu M
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 4762-4775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.2008
- Author(s)
  Sou YS, Waguri S, Iwata JI, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanaka K, Komatsu M
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 4762-4775
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury2008
- Author(s)
  Koike M, Shibata S, Tadakoshi T, Gotoh K, Komatsu M, Waguri S, Kawahara N, Kuida K, Nagata S, Kominami E, Tanaka K, Uchiyama Y
- Journal Title
  
  Am J Pathol 172
  
  Pages: 454-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers2008
- Author(s)
  Yoshida A, Miyata H, Doki Y, Yamasaki M, Sohma I, Gotoh K, Takiguchi S, Fujiwara Y, Uchiyama Y, Monden M
- Journal Title
  
  Int J Oncol 33
  
  Pages: 461-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.2008
- Author(s)
  Maeda Y, Ide T, Koike M, Uchiyama Y, Kinoshita T
- Journal Title
  
  Nat Cell Biol 10
  
  Pages: 1135-1145
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.2008
- Author(s)
  Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie Z-L, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, Zhou Y, Peng L, LuYM, Standaert DG, Walls KC, Shacka JJ, Roth KA, Zhang J
- Journal Title
  
  Mol Brain 1
  
  Pages: 17-17
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses2008
- Author(s)
  Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T.
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 3710-3719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Developing postmitotic mammalian neurons in vivo lacking. Apaf-1 and ergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy2008
- Author(s)
  Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, Zhu C
- Journal Title
  
  J Neurosci 28
  
  Pages: 1490-1497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagic neuron death in neonatal brain ischemia/hypoxia.2008
- Author(s)
  Uchiyama, Y.
- Journal Title
  
  Autophagy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector based strategy2008
- Author(s)
  Kiyohara Y, Nishii K, Ukai-Tadenuma M, Ueda H, Uchiyama Y, Yagita K
- Journal Title
  
  Nucl Acids Res 36(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Inefficient phagosome maturation in infant macrophages2008
- Author(s)
  Saito F, Kuwata H, Oiki E, Koike M, Uchiyama Y, Honda K, Takeda K
- Journal Title
  
  Biochem Biophys Res Commun 375
  
  Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagy-Physiology and Pathophysiology2008
- Author(s)
  Uchiyama, Y., Shibata, M., Koike, M., Yoshimura, K., Sasaki, M.
- Journal Title
  
  Histochem Cell Biol 129
  
  Pages: 407-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in renal ischemia/reperfusion injury.2008
- Author(s)
  Suzuki C, Takabatake Y, Tanaka H, Koike M, Shibata M, Uchiyama Y, Takahara S, Imai E, Isaka Y
- Journal Title
  
  BBRC 368
  
  Pages: 100-106
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagic neuron death in neonatal brain ischemia/hypoxia.2008
- Author(s)
  Uchiyama Y, Koike M, Shibata M
- Journal Title
  
  Autophagy 4
  
  Pages: 404-408
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus2008
- Author(s)
  Maeda Y, Ide T, Koike M, Uchiyama Y, Kinoshita T
- Journal Title
  
  Nat Cell Biol 10
  
  Pages: 1135-1145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.2007
- Author(s)
  Komatsu M, Ueno T, Waguri S, Uchiyama Y, Kominami E, Tanaka K
- Journal Title
  
  ell Death Diff 14
  
  Pages: 887-894
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells.2007
- Author(s)
  Hida T, Ikeda H, Kametaka S, Akazawa S, Kohsaka S, Ebisu S, Uchiyama Y, Waguri S
- Journal Title
  
  Arch Histol Cytol 70
  
  Pages: 303-312
- NAID
  10021186983
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Kainic acid induces early and transient autophagic stress in mouse hippocampus.2007
- Author(s)
  Shacka JJ, Lu J, Xie ZL, Uchiyama Y, Roth KA, Zhang J
- Journal Title
  
  Neurosci Lett 414
  
  Pages: 57-60
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Cathepsin D Deficiency Induces Persistent Neurodegeneration in the Absence of Bax-Dependent Apoptosis.2007
- Author(s)
  Shacka JJ, Klocke BJ, Young C, Shibata M, Olney JW, Uchiyama Y, Saftig P, Roth KA
- Journal Title
  
  J Neurosci 27
  
  Pages: 2081-2090
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.2007
- Author(s)
  Komatsu M, Waguri S, Koike M, Soul Y, Ueno T, Hara H, Mizushima N, Iwata J, Ezaki J, MurataS, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka T
- Journal Title
  
  Cell 131
  
  Pages: 1149-1163
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens.2007
- Author(s)
  Nakahara M, Nagasaka A, Koike M, Uchida K, Kawane K, Uchiyama Y, Nagata S
- Journal Title
  
  FEBS J 274
  
  Pages: 3055-3064
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Kainic acid induces early and transient autophagic stress in mouse hippocampus.2007
- Author(s)
  Shacka JJ, Lu J, Xie ZL, Uchiyama Y, Roth KA, Zhang J.
- Journal Title
  
  Neuroscience Letter 414
  
  Pages: 57-60
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice.2007
- Author(s)
  Yamasaki R, Zhang J, Koshiishi I, Suniarti DFS, Wu Z, Peters C, Schwake M, Uchiyama Y, Kira J, Saftig P, Utsumi H, Nakanishi H
- Journal Title
  
  Mol Cell Neurosci 35
  
  Pages: 573-584
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Identification of Tim-4 as a phosphatidylserine receptor.2007
- Author(s)
  Miyanishi M, Tada K, Koike M, Uchiyama Y, Kitamura T, Nagata S
- Journal Title
  
  Nature 450
  
  Pages: 435-439
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The luminal domain participates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor.2006
- Author(s)
  Waguri S, Tomiyama Y, Hida T, Sakai N, Taniike M, Wakasugi M, Ebisu S, Uchiyama Y
- Journal Title
  
  Exp. Cell Res 312
  
  Pages: 4090-4107
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Sleeping beauty transposon-based phenotypic analysis of mice : lack of Arpc3 results in defective trophoblast outgrowth.2006
- Author(s)
  Yae K, Keng VW, Koike M, Yusa K, Kouno M, Uno Y, Kondoh G, Gotow T, Uchiyama Y, Hone K, Takeda J.
- Journal Title
  
  Mol Cell Biol 26
  
  Pages: 6185-6196
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Bafilomycin Al Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons.2006
- Author(s)
  Shacka J, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA
- Journal Title
  
  Mol Pharacol 69
  
  Pages: 1125-1136
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Bafilomycin A1 Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons.2006
- Author(s)
  Shacka JJ, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA
- Journal Title
  
  Mol Pharacol 69
  
  Pages: 1125-1136
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Reguration of autophagy by extra cellular signal regulated protein kinases during 1-methy1-4-phenylpyridinium injury.2006
- Author(s)
  Zhu, J-H, Horbinski, C, Guo, F, Watkins, S, Uchiyama, Y., Chu, C.T.
- Journal Title
  
  American J of Pathology 170
  
  Pages: 75-86
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The luminal domain pirticipates in the endosomal trafficking of the cation-independent mannose 6-Thosphate receptor.2006
- Author(s)
  Wagnri; S, Tomiyama., Y, Hida, T, Sakai, N, Taniikei M, Wakasugi, M, Ebisu, S, Uchiyama, Y.
- Journal Title
  
  Experimental Cell Research. 312
  
  Pages: 4090-4102
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia.2006
- Author(s)
  Zyu C, Xu F, Wang X, Shibata M, Uchiyama Y, Blomgren K, Hagberg H
- Journal Title
  
  J Neurochem 96
  
  Pages: 1016-1027
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis.2006
- Author(s)
  Ishii M, Iwai K, Koike M, Ohshima S, Kudo-Tanaka E, Ishii T, Mima T, Katada Y, Miyatake K, Uchiyama Y, Saeki Y.
- Journal Title
  
  J Bone Miner Res 21
  
  Pages: 965-976
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues.2006
- Author(s)
  Yoshimura K, Shibata, Koike M, Gotoh K, Fukaya M, Watanabe M, Uchiyama, Y.
- Journal Title
  
  Autop6gy 2
  
  Pages: 200-208
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues.2006
- Author(s)
  Yoshimura K, Shibata M, Koike M, Gotoh K, Fukaya M, Watanabe M, Uchiyama Y
- Journal Title
  
  Autophagy 2
  
  Pages: 200-208
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Reguration of autophagy by extracellular signal regulated protein kinases during 1-methyl-4-phenylpyridinium injury.2006
- Author(s)
  Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT
- Journal Title
  
  Am J Pathol 170
  
  Pages: 75-86
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia.2006
- Author(s)
  Zhu C, Xu F, Wang X, Shibata M, Uchiyama Y, Blomgren K, Hagberg H
- Journal Title
  
  J Neurochem 96
  
  Pages: 1016-1027
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Bafilomycin A1 Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons.2006
- Author(s)
  Shacka J, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA
- Journal Title
  
  Mol Pharacl mol. 105
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Uncoupling protein 2 negatively regulates neurite extensions in PC12h cells.2006
- Author(s)
  Yamada S, Isojima Y, Kanamori S, Waguri S, Uchiyama Y, Nagai K.
- Journal Title
  
  Neurosci Lett 410(2)
  
  Pages: 110-114
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants.2006
- Author(s)
  Sasaki T, Gotow T, Shiozaki M, Sakaue F, Saito T, Julien JP, Uchiyama Y, Hisanaga S.
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration.2006
- Author(s)
  Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Ueno T, Koike M, Uchiyama Y, Kominami E' Tanaka K
- Journal Title
  
  Nature 441
  
  Pages: 880-884
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Gene transfer of HGF gene improves learning and memory in the chronic stage of cerebral infarction.2006
- Author(s)
  Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita R
- Journal Title
  
  Hypertension 47
  
  Pages: 742-751
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration.2006
- Author(s)
  Komatsu M*, Waguri S*, Chiba T, Murata S, Iwata J, Ueno oike M, Uchiyama Y, Kominami E, Tanaka K, (*equally contributed)
- Journal Title
  
  Nature 441
  
  Pages: 880-884
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Rles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking.2005
- Author(s)
  Hye-Won Shin, Hiromi Kobayashi, Masashi Kitamura, Satoshi Waguri, Tatsuo Suganuma, Yasuo Uchiyama, Kazuhisa Nakayama
- Journal Title
  
  J Cell Sci 118
  
  Pages: 4039-4048
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in the degeneration process of rat hepatocytes after transplantation following prolonged cold preservation.2005
- Author(s)
  CDLuZ, DonoK, GotohK, Shibata M, Koike M, Marubashi S, Miyamoto A, Takeda Y, Nagano H, Umeshita K, Uchiyama Y, Monden M
- Journal Title
  
  Arch Histol Cytol 68
  
  Pages: 71-80
- NAID
  10015565050
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).2005
- Author(s)
  Koike M, Shibata M, Waguri S, Yoshimura K, Tanida I, Kominami E, Gotow G, Peters C, Figura Kv, Mizushima N, Saftig P, Uchiyama Y
- Journal Title
  
  Am J Pathol 167
  
  Pages: 1713-1728
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Proteolytic Degradation of Glutamate Decarboxylase Mediates Disinhibition of Hippocamepal CA3 Pyramidal Cells in Cathepsin D-deficient Mice.2005
- Author(s)
  Shimizu, T., Hayashi, Y., Yamada, J., Zhang, J., Yamasaki, J., Ukai, K., Koike, M., Mine, K., Figura, K., Peters, C., Saftig, P., Fukuda, T., Uchiyama, Y., Nakanishi, H.
- Journal Title
  
  J Neurochem 94
  
  Pages: 680-690
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Application of fluorophore-assisted carbohydrate electrophoresis to analysis of disaccharides and oligosaccharides derived from glycosaminoglycans.2005
- Author(s)
  Oonuki Y, Yoshida Yhosi, Uchiyama Y, Asari A
- Journal Title
  
  Anal Biochem 343
  
  Pages: 212-222
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Phosphatidylserine妖ependent engulfment by macrophages of nuclei from erythroid precursor cells.2005
- Author(s)
  Yoshida H, Kawane K, Koike M, Mori Y, Uchiyama Y, Nagata, S
- Journal Title
  
  Nature 434
  
  Pages: 754-758
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in the degeneration process of rat hepatocytes after transplantation following prolonged cold preservation.2005
- Author(s)
  Lu Z, Dono K, Gotoh K, Shibata M, Koike M, Marubashi S, Miyamoto A, Takeda Y, Nagano H, Umeshita K, Uchiyama Y, Monden M
- Journal Title
  
  Arch Histol Cytol 68
  
  Pages: 71-80
- NAID
  10015565050
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Proteolytic Degradation of Glutamate Decarboxylase Mediates Disinhibition of Hippocampal CA3 Pyramidal Cells in Cathepsin D-deficient Mice.2005
- Author(s)
  Shimizu T, Hayashi Y, Yamada J, Zhang J, Yamasaki J, Ukai K, Koike M, Mine K, Figura Kv, Peters C, Saftig P, Fukuda T, Uchiyama Y, Nakanishi H
- Journal Title
  
  J Neurochem 94
  
  Pages: 680-690
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Macroautophagy- a novel amyloid-b (Ab) peptide-generating athway activated in alzheimer's disease.2005
- Author(s)
  Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, J Naslund, Mathews PM, Cataldo AM, Nixon RA
- Journal Title
  
  J Cell Biol 171
  
  Pages: 87-98
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.2005
- Author(s)
  Zhu C, Wang X, Xu F, Bahr BA, Shibata M, Uchiyama Y, Hagberg H, Blomgren K
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 162-176
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.2005
- Author(s)
  Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T
- Journal Title
  
  J Cell Biol 169
  
  Pages: 425-434
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells.2005
- Author(s)
  Yoshida H, Kawane K, Koike M, Mori Y, Uchiyama Y, Nagata S
- Journal Title
  
  Nature 434
  
  Pages: 754-758
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Human herpesvirus 6 ORF14 protein and cellular p53 interact with each other and are contained in the virus.2005
- Author(s)
  Takemoto M, Koike M, Mori Y, Yonemoto S, Sasamoto Y, Kondo K, Uchiyama Y, Yamanishi K
- Journal Title
  
  J Virol 79
  
  Pages: 13037-13046
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid^lipofuscinoses (Batten disease).2005
- Author(s)
  Koike M, Shibata M, Waguri S, Yoshimura K, Tanida I, Kominami E, Gotow G, Peters C, Figura Kv, Mizushima N, Saftig P, Uchiyama Y
- Journal Title
  
  Am J Pathol 167
  
  Pages: 1713-1728
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Macroautophagy-a novel amyloid-b (Ab) peptide-generating athway activated in alzheimer's disease.2005
- Author(s)
  Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, J Naslund, Mathews PM, Cataldo AM, Nixon RA
- Journal Title
  
  J Cell Biol 171
  
  Pages: 87-98
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] PKCλ in pancreatic β-cells mediates glucose-induced insulin secretion via the regulation of gene expression.2005
- Author(s)
  Hashimoto N, kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Uchiyama Y, Ohno S, Noda T, Kasuga M
- Journal Title
  
  J Clin Inv 115
  
  Pages: 138-145
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice.2004
- Author(s)
  0HanayamaR, Tanaka M, Miyasaka K, Aozasa K, Koike M, Uchiyama Y, Nagata S
- Journal Title
  
  Science 304
  
  Pages: 1147-1150
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease.2004
- Author(s)
  Yu WH, Kumar A, Peterhoff C, Shapiro Kulnane L, Uchiyama Y, Lamb BT, Cuervo AM, Nixon RA
- Journal Title
  
  Int J Biochem Cell Biol 36
  
  Pages: 2531-2540
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Early-phase redistribution of the cation-independent mannose 6-phosphate receptor by U18666A treatment in HeLa cells.2004
- Author(s)
  Wl'omiyama Y, Waguri S, Kanamori S, Kametaka S, Wakasugi M, Shibata M, Ebisu S, Uchiyama Y
- Journal Title
  
  Cell Tissue Res 317
  
  Pages: 253-264
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] 脂肪滴とオートファジー2001
- Author(s)
  内山安男
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 33(4) Pages: 338-343
- Data Source
  KAKENHI-PROJECT-23659102
[Journal Article] Altered Regulation of Phosphatidylinositol 3-kinase Signaling in Cathepsin D-Deficient Brain.
- Author(s)
  Walls KC, Klocke, BJ, Saftig, P, Shibata, M, Uchiyama, Y, Roth, KA, Shacka, JJ.
- Journal Title
  
  Autophagy (In press)
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration.
- Author(s)
  Komatsu M, Waguri S(2人は同等の貢献), Chiba T, Murata S, Iwata J, Ueno Koike, Uchiyama Y, Kominami E, Tanaka K
- Journal Title
  
  Nature (In press)
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization
- Author(s)
  Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J, Yoshida T, Sato T, Peters C, Mochizuki M, Morita I
- Journal Title
  
  Am J Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Geno transfer of HGF gene improves learning and memory in the chronic stage of cerebral infarction.
- Author(s)
  Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita R
- Journal Title
  
  Hypertension (In press)
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] Cathepsin D Deficiency Induces Persistent Neurodegeneration in the Absence of Bax-Dependent Apoptosis.
- Author(s)
  Shacka JJ, Klocke BJ, Young C, Shibata M, OIlney JW, Uchiyama Y, Saftig P, Roth KA
- Journal Title
  
  J Neuroscience (In press)
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] C-terminal Src kinase controls development and maintenance of mouse squamous epithelia.
- Author(s)
  Yagi R, Wagui S, Sumikawa S, Nada S, Oneyama C, Itami S, Schmedt C, Uchiyama Y, Okada M
- Journal Title
  
  EMBOJ (In press)
- Data Source
  KAKENHI-PROJECT-16GS0315
[Journal Article] JE Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1^<H46R_> Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
- Author(s)
 Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya A, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda
- Journal Title
 
 PLoSONE (in press)
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-16GS0315
[Presentation] 神経細胞におけるリソソームタンパク質分解とその破綻2016
- Author(s)
  内山安男
- Organizer
  第１２１回日本解剖学会総会
- Place of Presentation
  福島県郡山市
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Cell death and autophagy2015
- Author(s)
  Yasuo Uchiyama
- Organizer
  The 24th International Symposium on Morphological Science
- Place of Presentation
  Turky Istanbul
- Year and Date
  2015-09-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] The LC3 conjugation system is involved in lipid droplet formation2015
- Author(s)
  Yasuo Uchiyama
- Organizer
  The 2nd Congress, International Academy of Sportology
- Place of Presentation
  Tokyo
- Year and Date
  2015-09-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 神経細胞の極性とオートファジー2014
- Author(s)
  内山　安男
- Organizer
  第１９回グリアクラブ特別講演
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] リソソーム蓄積症とオートファジー (学術教育講演)2014
- Author(s)
  内山　安男
- Organizer
  第１１９回日本解剖学会総会•全国学術集会
- Place of Presentation
  自治医科大学
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] 神経系におけるオートファジー2014
- Author(s)
  内山　安男
- Organizer
  大阪大学蛋白質研究所セミナー「オートファジーと疾患」
- Place of Presentation
  大阪大学蛋白質研究所
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] リソソーム蓄積症とオートファジー (学術教育講演)2014
- Author(s)
  内山　安男
- Organizer
  第１１９回日本解剖学会総会•全国学術集会
- Place of Presentation
  自治医科大学
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 神経細胞の極性とオートファジー2014
- Author(s)
  内山　安男
- Organizer
  第１９回グリアクラブ特別講演
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] オートファジーと認知症2014
- Author(s)
  内山安男
- Organizer
  第２０回近畿老年期認知症研究会
- Place of Presentation
  大阪
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] GBA変異メダカは脳にalpha-synuclein凝集体を形成する2014
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、植村健吾、内山安男、藤堂剛、武田俊一、髙橋良輔
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] Neuronopathic Gaucher’s disease model of medaka displayed axonal accumulation of alpha-synuclein2014
- Author(s)
  Norihito Uemura, Masato Koike, Masato Kinoshita, Tomoko Fujiwara-Ishikawa, Hideaki Matsui, Hodaka Yamakado,Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda, Ryosuke Takahashi
- Organizer
  4th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress
- Place of Presentation
  Thailand
- Year and Date
  2014-11-30
- Invited
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] 神経細胞の極性とオートファジー2014
- Author(s)
  内山　安男
- Organizer
  第１９回グリアクラブ特別講演
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] 神経系におけるオートファジー2014
- Author(s)
  内山安男
- Organizer
  第５５回に本組織細胞化学会総会
- Place of Presentation
  松本
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Alpha-synuclein accumulation in Gaucher disease model of medaka does not contribute to neurodegeneration2014
- Author(s)
  Norihito Uemura, Tomoko Fujiwara-Ishikawa, Masato Kinoshita, Masato Koike, Hideaki Matsui, Hodaka Yamakado, Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda and Ryosuke Takahashi
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] 低酸素脳虚血障害とLC3 欠損マウス2014
- Author(s)
  山口隼司, 砂堀毅彦, 七尾友久, 佐々木光穂, 小池正人, 内山安男
- Organizer
  第19回グリアクラブ
- Place of Presentation
  新潟県湯沢
- Year and Date
  2014-03-02
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] GBA変異メダカは軸索内にalpha-synucleinを蓄積する2014
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、内山安男、藤堂剛、武田俊一、髙橋良輔
- Organizer
  第23回日本Cell Death学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] 神経系におけるオートファジー2014
- Author(s)
  内山安男
- Organizer
  第５５回に本組織細胞化学会総会
- Place of Presentation
  松本
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] オートファジーと認知症2014
- Author(s)
  内山安男
- Organizer
  第２０回近畿老年期認知症研究会
- Place of Presentation
  大阪
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] 神経系におけるオートファジー2014
- Author(s)
  内山　安男
- Organizer
  大阪大学蛋白質研究所セミナー「オートファジーと疾患」
- Place of Presentation
  大阪大学蛋白質研究所
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 中枢神経系におけるLC3A/B の役割2014
- Author(s)
  山口隼司, 砂堀毅彦, 七尾友久, 佐々木光穂, 小池正人, 内山安男
- Organizer
  第119回日本解剖学会総会
- Place of Presentation
  自治医科大学
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 神経系におけるオートファジー2014
- Author(s)
  内山　安男
- Organizer
  大阪大学蛋白質研究所セミナー「オートファジーと疾患」
- Place of Presentation
  大阪大学蛋白質研究所
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] リソソーム蓄積症とオートファジー (学術教育講演)2014
- Author(s)
  内山　安男
- Organizer
  第１１９回日本解剖学会総会•全国学術集会
- Place of Presentation
  自治医科大学
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] GBAノックアウトメダカは脳にアルファシヌクレイン凝集体を形成する2013
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、植村健吾、内山安男、藤堂剛、武田俊一、高橋良輔
- Organizer
  第22回日本Cell Death学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2013-07-19
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] メダカを用いたGBA変異とパーキンソン病の関連性の解析2013
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、植村健吾、内山安男、藤堂剛、武田俊一、高橋良輔
- Organizer
  日本神経学会
- Place of Presentation
  東京都
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain2013
- Author(s)
  Norihito Uemura, Tomoko Fujiwara-Ishikawa, Masato Kinoshita, Masato Koike, Hideaki Matsui, Hodaka Yamakado, Kengo Uemura, Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda and Ryosuke Takahashi
- Organizer
  17th international congress of Parkinson's disease and movement disorders
- Place of Presentation
  Ｓｙｄｎｅｙ
- Year and Date
  2013-06-20
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain2013
- Author(s)
  Norihito Uemura, Tomoko Fujiwara-Ishikawa, Masato Kinoshita, Masato Koike, Hideaki Matsui, Hodaka Yamakado, Kengo Uemura, Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda and Ryosuke Takahashi
- Organizer
  Neuroscience 2013
- Place of Presentation
  SanDiego
- Year and Date
  2013-11-10
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] Memorial lecture for the Late Prof. emer. Tsuneo Fujita – Lesson from “Science” of Prof. Fujita.2013
- Author(s)
  Yasuo Uchiyama
- Organizer
  The 23rd International Symposium on Morphological Sciences
- Place of Presentation
  Niigata
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] Memorial lecture for the Late Prof. emer. Tsuneo Fujita – Lesson from “Science” of Prof. Fujita.2013
- Author(s)
  Yasuo Uchiyama
- Organizer
  The 23rd International Symposium on Morphological Sciences
- Place of Presentation
  Niigata
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 極性のあるニューロンへのリソソームオートファゴソームの局在について2013
- Author(s)
  内山安男
- Organizer
  日本薬学会１３３年会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain2013
- Author(s)
  Norihito Uemura, Tomoko Fujiwara-Ishikawa, Masato Kinoshita, Masato Koike, Hideaki Matsui, Hodaka Yamakado, Kengo Uemura, Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda and Ryosuke Takahashi
- Organizer
  日本神経科学学会
- Place of Presentation
  京都市
- Year and Date
  2013-06-22
- Data Source
  KAKENHI-ORGANIZER-23111001
[Presentation] Memorial lecture for the Late Prof. emer. Tsuneo Fujita – Lesson from “Science” of Prof. Fujita.2013
- Author(s)
  Yasuo Uchiyama
- Organizer
  The 23rd International Symposium on Morphological Sciences
- Place of Presentation
  Niigata
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 極性のあるニューロンへのリソソームオートファゴソームの局在について2013
- Author(s)
  内山安男
- Organizer
  日本薬学会１３３年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-03-28
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 極性のあるニューロンへのリソソームオートファゴソームの局在について2013
- Author(s)
  内山安男
- Organizer
  日本薬学会１３３年会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] mAtg9A-AcGFPおよびmDFCP1-mCherryトランスジェェニックマウスの作製2012
- Author(s)
  佐々木光穂、多村博澄、多田昇弘、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse after hypoxic-ischemic injury2012
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Cell death and autophagy2012
- Author(s)
  Uchiyama, Y
- Organizer
  The XXII International Symposium on Morphological Sciences
- Place of Presentation
  Sao Paulo in Brazil(招待講演)
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Hyaluronan tetrasaccharide rescues hippocampal pyramidal neuron death after hypoxic-ischemic injury.2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第１４回国際組織細胞化学会（ICHC２０１２）
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-08-26
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] カテプシンBDダブルノックアウトマウスの中枢神経系の形態学的解析2012
- Author(s)
  小池正人、山口隼司、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] リソソーム蓄積症とオートファジー2012
- Author(s)
  内山安男
- Organizer
  平成23年度蛋白研セミナー神経疾患の克服に向けて
- Place of Presentation
  大阪大学蛋白質研究所(招待講演)
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] リソソーム蓄積症とオートファジー2012
- Author(s)
  内山安男
- Organizer
  平成23年度蛋白研セミナー神経疾患の克服に向けて
- Place of Presentation
  大阪大学蛋白質研究所(招待講演)
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 鼻プラコード由来ソマトスタチン mRNA 陽性細胞の前脳進入と定着2012
- Author(s)
  村上志津子、浜崎浩子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] 正常および老齢マウス脳におけるリソゾームカテプシン C の分布2012
- Author(s)
  小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Cell death and autophagy2012
- Author(s)
  Uchiyama Y
- Organizer
  The XXII International Symposium on Morphological Sciences
- Place of Presentation
  Sao Paulo in Brasil
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Cell death and autophagy2012
- Author(s)
  Uchiyama, Y
- Organizer
  The XXII International Symposium on Morphological Sciences
- Place of Presentation
  Sao Paulo in Brazil(招待講演)
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Characteristic differences between Purkinje cells specifically deficient in cathepsin D and Atg72012
- Author(s)
  Yasuo Uchiyama
- Organizer
  6th International Symposium on Autophagy
- Place of Presentation
  沖縄　万国津梁館
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 初代培養神経細胞の成熟過程に見られるリソソーム/オートファジー関連タンパク質の動態2012
- Author(s)
  七尾友久、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] mAtg9A-AcGFPおよびmDFCP1-mCherryトランスジェェニックマウスの作製2012
- Author(s)
  佐々木光穂、多村博澄、多田昇弘、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse after hypoxic-ischemic injury2012
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Hyaluronan tetrasaccharide rescues hippocampal pyramidal neuron death after hypoxic-ischemic injury.2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第１４回国際組織細胞化学会（ICHC２０１２）
- Place of Presentation
  国立京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Characteristic differences between Purkinje cells specifically deficient in cathepsin D and Atg72012
- Author(s)
  Yasuo Uchiyama
- Organizer
  6th International Symposium on Autophagy
- Place of Presentation
  沖縄　万国津梁館
- Invited
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Autophagy in the neural network and its impairment2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Autophagy in the neural network and its impairment2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] 正常および老齢マウス脳におけるリソゾームカテプシンCの分布2012
- Author(s)
  小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] ほ乳類 Atg9AmRNA ノックダウンHeLa 細胞について/A study on Atg9AmRNA-knockdown HeLa cells2012
- Author(s)
  多村博澄、佐々木光穂、小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Autophagy in the neural network and its impairment2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 初代培養神経細胞の成熟過程に見られるリソソーム/オートファジー関連タンパク質の動態2012
- Author(s)
  七尾友久、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 発生初期過程の脳における PSA-NCAM 陽性周皮細胞の動態2012
- Author(s)
  宮川桃子、石龍徳、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] リソソーム膜タンパク質 LAMP-2 の中枢神経系における役割2012
- Author(s)
  古田晶子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] 初代培養神経細胞の成熟過程に見られるリソソーム／オートファジー関連タンパク質の動態2012
- Author(s)
  七尾友久、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] 発生初期過程の脳におするPSA-NCAM陽性周皮細胞の動態2012
- Author(s)
  宮川桃子、石龍徳、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] カテプシンBDダブルノックアウトマウスの中枢神経系の形態学的解析2012
- Author(s)
  小池正人、山口隼司、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse after hypoxic-ischemic injury2012
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] カテプシンBDダブルノックアウトマウスの中枢神経系の形態学的解析2012
- Author(s)
  小池正人、山口隼司、内山安男
- Organizer
  第17回グリアクラブ
- Place of Presentation
  ヒルトンニセコビリッジ
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] リソソーム膜タンパク質LAMP-2の中枢神経系における役割2012
- Author(s)
  古田晶子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Characteristic differences between Purkinje cells specifically deficient in cathepsin D and Atg72012
- Author(s)
  Yasuo Uchiyama
- Organizer
  6th International Symposium on Autophagy
- Place of Presentation
  沖縄　万国津梁館
- Year and Date
  2012-10-28
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 正常および老齢マウス脳におけるリソゾームカテプシンCの分布2012
- Author(s)
  小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] ほ乳類Atg9AmRNAノックダウンHeLa細胞について/A study on Atg9AmRNA-knockdown HeLa cells2012
- Author(s)
  多村博澄、佐々木光穂、小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Hyaluronan tetrasaccharide rescues hippocampal pyramidal neuron death after hypoxic-ischemic injury.2012
- Author(s)
  Yasuo Uchiyama
- Organizer
  第１４回国際組織細胞化学会（ICHC２０１２）
- Place of Presentation
  国立京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] ほ乳類Atg9AmRNAノックダウンHeLa細胞について/A study on Atg9AmRNA-knockdown HeLa cells2012
- Author(s)
  多村博澄、佐々木光穂、小池正人、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 鼻プラコード由来ソマトスタチンmRNA陽性細胞の前脳進入と定着2012
- Author(s)
  村上志津子、浜崎浩子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] リソソーム膜タンパク質LAMP-2の中枢神経系における役割2012
- Author(s)
  古田晶子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 鼻プラコード由来ソマトスタチンmRNA陽性細胞の前脳進入と定着2012
- Author(s)
  村上志津子、浜崎浩子、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 発生初期過程の脳におけるPSA-NCAM陽性周皮細胞の動態2012
- Author(s)
  宮川桃子、石龍徳、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] The autophagy/lysosomal system is essential for the maintenance of the axon and its terminal2011
- Author(s)
  Uchiyama, Y
- Organizer
  Invited speaker in "Synapse in 2011"
- Place of Presentation
  Lake Maggiore in Italy
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PUBLICLY-23110517
[Presentation] Possible roles of LC3, ubiquitin, and P62 and/or Nbr1 in the accumulation of lysosomes in neurons deficient in Cathepsin D2011
- Author(s)
  Masato Koike, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse brains after hypoxic-ischemic injury2011
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] 虚血生侵襲に対するヒアルロン酸4糖の神経細胞保護効果の検討2011
- Author(s)
  砂堀毅彦、小池正人、内山安男
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横兵
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] カテプシンD欠損に伴う神経性ロイドリポフスチン蓄積症の病態形成にオートファジーが果たす役割について2011
- Author(s)
  小池正人、内山安男
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Possible roles of LC3, ubiquitin, and P62 and/or Nbr1 in the accumulation of lysosomes in neurons deficient in Cathepsin D2011
- Author(s)
  Koike M, Uchiyama, Y
- Organizer
  Neuroscience 2011(アメリカ神経科学会総会)
- Place of Presentation
  Washington, D.C.(ポスター発表)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PUBLICLY-23110517
[Presentation] Property of lysosomal storage disease in the CNS of lysosome-associated membrane protein-2 deficient mice2011
- Author(s)
  Furuta A, Wada K, Uchiyama, Y
- Organizer
  Neuroscience 2011(アメリカ神経科学会総会)
- Place of Presentation
  Washington, D.C.(ポスター発表)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23110517
[Presentation] Generation of mAtg9A transgenic mice.2011
- Author(s)
  Sasaki Mitsuho, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] The autophagy/lysosomal system is essential for the maintenance of the axon and its terminal2011
- Author(s)
  Uchiyama Y
- Organizer
  The synapse from physiology to pathology
- Place of Presentation
  Stresa in Italy
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Possible roles of LC3, ubiquitin, and P62 and/or Nbr1 in the accumulation of lysosomes in neurons deficient in Cathepsin D2011
- Author(s)
  Masato Koike, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse brains after hypoxic-ischemic injury2011
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  41 st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Acceleration of autophagy results in neurodegeneration2011
- Author(s)
 Uchiyama, Y
- Organizer
 Plenary Lecture in The 10^<th> China-Japan Joint Seminar on Histochemistry and Cytochemistry
- Place of Presentation
 Beijin
- Year and Date
 2011-10-22
- Data Source
 KAKENHI-PUBLICLY-23110517
[Presentation] 虚血生侵襲に対するヒアルロン酸４糖の神経細胞保護効果の検討2011
- Author(s)
  砂堀毅彦、小池正人、内山安男
- Organizer
  第３４回日本神経科学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] カテプシンD欠損に伴う神経性ロイドリポフスチン蓄積症の病態形成にオートファジーが果たす役割について2011
- Author(s)
  小池正人、内山安男
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Acceleration of autophagy results in neurodegeneration2011
- Author(s)
  Uchiyama, Y
- Organizer
  第10回日中合同組織細胞化学セミナー
- Place of Presentation
  中国北京市首都医科大学(招待講演)
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Generation of mAtg9A transgenic mice2011
- Author(s)
  Sasaki M, Uchiyama, Y
- Organizer
  Neuroscience 2011(アメリカ神経科学会総会)
- Place of Presentation
  Washington, D.C.(ポスター発表)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23110517
[Presentation] 虚血生侵襲に対するヒアルロン酸4糖の神経細胞保護効果の検討2011
- Author(s)
  砂堀毅彦、小池正人、内山安男
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Acceleration of autophagy results in neurodegeneration2011
- Author(s)
  Uchiyama Y
- Organizer
  第10回日中合同組織細胞化学セミナー
- Place of Presentation
  北京
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] カテプシンD欠損に伴う神経性ロイドリポフスチン蓄積症の病態形成にオートファジーが果たす役割について2011
- Author(s)
  小池正人、内山安男
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Possible roles of LC3, ubiquitin, and P62 and/or Nbr1 in the accumulation of lysosomes in neurons deficient in Cathepsin D2011
- Author(s)
  Masato Koike, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] 腎虚血尿細管傷害におけるオートファジー・リソソーム系の関わりについて2011
- Author(s)
  鈴木ちぐれ、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] Acceleration of autophagy results in neurodegeneration2011
- Author(s)
  Uchiyama, Y
- Organizer
  第10回日中合同組織細胞化学セミナー
- Place of Presentation
  中国北京市首都医科大学(招待講演)
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] mAtg9A-AcGFP および mDFCP1-mCherry トランスジェェニックマウスの作製2011
- Author(s)
  佐々木光穂、多村博澄、多田昇弘、内山安男
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス
- Data Source
  KAKENHI-PROJECT-23659102
[Presentation] The autophagy/lysosomal system is essential for the maintenance of the axon and its terminal2011
- Author(s)
  Uchiyama, Y
- Organizer
  The synapse from physiology to pathology
- Place of Presentation
  Stresa in Italy(招待講演)
- Data Source
  KAKENHI-PROJECT-23390041
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse brains after hypoxic-ischemic injury2011
- Author(s)
  Sunabori Takehiko, Masato Koike, Yasuo Uchiyama
- Organizer
  41st Annual Meeting Society for Neuroscience
- Place of Presentation
  ワシントン・コンベンション・センター
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] The autophagy/lysosomal system is essential for the maintenance of the axon and its terminal2011
- Author(s)
  Uchiyama, Y
- Organizer
  The synapse from physiology to pathology
- Place of Presentation
  Stresa in Italy(招待講演)
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] Protective effects of hyaluronan tetrasaccharide on hippocampal pyramidal neurons in neonatal mouse brains after hypoxic-ischemic injury2011
- Author(s)
  Sunabori T, Koike M, Uchiyama, Y
- Organizer
  Neuroscience 2011(アメリカ神経科学会総会)
- Place of Presentation
  Washington, D.C.(ポスター発表)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PUBLICLY-23110517
[Presentation] オートファジー/リソソームを追って2010
- Author(s)
  内山安男
- Organizer
  平成22年度日本組織細胞化学会高松賞受賞講演(第51回日本組織化学会)
- Place of Presentation
  秋葉原コンベンションホール
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21659050
[Presentation] Cell death and autophagy.2010
- Author(s)
  Uchiyama Y
- Organizer
  22nd International Symposium on Morphological Sciences
- Place of Presentation
  イタリアタオルミナ
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21659050
[Presentation] Autophagy and other pathomechanisms2009
- Author(s)
 内山安男
- Organizer
 12^<th> International Congress on Neuronal Ceroid Lipofuscinoses(NCL)
- Place of Presentation
 ドイツハンブルグ
- Year and Date
 2009-06-05
- Data Source
 KAKENHI-PROJECT-21659050
[Presentation] Involvement of autophagy in pathogenesis of neuronal ceroid lipofuscinosis2009
- Author(s)
  Uchiyama Y
- Organizer
  12th International Congress on Neuronal Ceroid Lipofuscinoses (NCL) in Hamburg
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Cell Death and Autophagy2009
- Author(s)
  内山安男
- Organizer
  International Symposium on Autophagy and Cell Death
- Place of Presentation
  順天堂大学医学研究科老人性疾患病態・治療研究センター
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Autophagy and cell death2009
- Author(s)
 内山安男
- Organizer
 5^<th> International Symposium on Autophagy
- Place of Presentation
 大津プリンスホテルコンベンションホール
- Data Source
 KAKENHI-PROJECT-16GS0315
[Presentation] Autophagy and cell death2009
- Author(s)
 内山安男
- Organizer
 5^<th> International Symposium on Autophagy
- Place of Presentation
 大津プリンスホテルコンベンションホール
- Data Source
 KAKENHI-PROJECT-21659050
[Presentation] Cell Death and Autophagy2009
- Author(s)
  内山安男
- Organizer
  International Symposium on Autophagy and Cell Death
- Place of Presentation
  順天堂大学医学研究科老人性疾患病態・治療研究センター
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21659050
[Presentation] Morphological aspects of autophagy : Identification and possible mechanism of autophagosome formation in neuronal cells2009
- Author(s)
  内山安男
- Organizer
  Microscopy Conference 2009
- Place of Presentation
  オーストリアグラーツ
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Morphological aspects of autophagy : Identification and possible mechanism of autophagosome formation in neuronal cells2009
- Author(s)
  内山安男
- Organizer
  Microscopy Conference 2009
- Place of Presentation
  オーストリアグラーツ
- Data Source
  KAKENHI-PROJECT-21659050
[Presentation] Morphological features of programmed cell death across the eukaryotic kingdom2009
- Author(s)
 内山安男
- Organizer
 6^<th> ISEM09 Committee
- Place of Presentation
 神戸大学
- Year and Date
 2009-09-17
- Data Source
 KAKENHI-PROJECT-21659050
[Presentation] Morphological features of programmed cell death across the eukaryotic kingdom2009
- Author(s)
 内山安男
- Organizer
 6^<th> ISEM09 Committee
- Place of Presentation
 神戸大学
- Year and Date
 2009-09-17
- Data Source
 KAKENHI-PROJECT-16GS0315
[Presentation] Autophagy and other pathomechanisms2009
- Author(s)
 内山安男
- Organizer
 12^<th> International Congress on Neuronal Ceroid Lipofuscinoses(NCL)
- Place of Presentation
 ドイツハンブルグ
- Year and Date
 2009-06-05
- Data Source
 KAKENHI-PROJECT-16GS0315
[Presentation] p62/A170/SQSTM1, a binding partner of ubiquitin and LC3, and lysosomal storage Disorder2008
- Author(s)
  内山安男
- Organizer
  第5回アジア太平洋解剖学会(APICA)
- Place of Presentation
  イランテヘラン
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] p62/A170/SQSTM1, a binding partner of ubiquitin and LC3, and lysosomal storage disorder2008
- Author(s)
  Uchiyama Y
- Organizer
  Neuroscience 2008 in the 31st Annual Meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Impairment and acceleration of autophagy result in neurodegeneration.2008
- Author(s)
  Uchiyama Y
- Organizer
  The 5th Asia Pacific International Congress of Anatomists
- Place of Presentation
  Tehran
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] p62/A170/SQSTM1, a binding partner of ubiquitin and LC3, and lysosomal storage Disorder2008
- Author(s)
  内山安男
- Organizer
  第31回日本神経科学会シンポジウム(SY3AE1)
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Impairment and acceleration of autophagy: neurodegeneration2008
- Author(s)
  Uchiyama Y
- Organizer
  In the 20th International Symposium on Morphological Science in Timisoara
- Place of Presentation
  Plenary Lecture
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] オートファジー/リソソーム制裁防止の分子細胞生物学的研究2008
- Author(s)
  内山安男
- Organizer
  平成20年度顕微鏡学会瀬藤賞受賞講演
- Place of Presentation
  千葉大学
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] オートラァジー/リソソーム制裁防正万秀子細胞生物学的研究2008
- Author(s)
  内山安男
- Organizer
  平成2 0年度顕微鏡学会瀬藤賞受賞講演
- Place of Presentation
  千葉大学
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] In: Neuronal macroautophagy, autophagic stress, and neurological diseses2007
- Author(s)
  Uchiyama Y
- Organizer
  Neuroscience
- Place of Presentation
  in San Diego
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Involvement of autophagy in neuron death of neonatal mouse brains after hypoxic-ischemic injury2006
- Author(s)
  Uchiyama Y
- Organizer
  In: The 4th Internation Symposium of Autophagy
- Place of Presentation
  in Mishima
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten Disease)2005
- Author(s)
  Uchiyama Y, Shibata M, Koike M
- Organizer
  International conference on serine-carboxyl peptidases and related enzymes
- Place of Presentation
  in Kyoto
- Year and Date
  2005-11-10
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] Roles of lysosomal proteinases in autophagic cell death2005
- Author(s)
  Uchiyama Y
- Organizer
  2005 Gordon Research Conference on "Autophagy in Stress, Development & Disease" in Il
- Place of Presentation
  Ciocco
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] cathepsin D deficiency induces caspase dependent and independent neuron death2004
- Author(s)
  Uchiyama Y
- Organizer
  Symp-55, 16th International congress of the IFAA
- Data Source
  KAKENHI-PROJECT-16GS0315
[Presentation] 電子顕微鏡方法論.
- Author(s)
  内山　安男
- Organizer
  （独）医薬基盤研セミナー
- Place of Presentation
  （独）医薬基盤研究所
- Invited
- Data Source
  KAKENHI-PROJECT-25670099
[Presentation] 電子顕微鏡方法論
- Author(s)
  内山　安男
- Organizer
  （独）医薬基盤研セミナー
- Place of Presentation
  （独）医薬基盤研究所
- Invited
- Data Source
  KAKENHI-PLANNED-23111004
[Presentation] 電子顕微鏡方法論
- Author(s)
  内山　安男
- Organizer
  （独）医薬基盤研セミナー
- Place of Presentation
  （独）医薬基盤研究所
- Invited
- Data Source
  KAKENHI-PROJECT-23390041

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Uchiyama Yasuo 内山 安男

UCHIYAMA Yasuo 内山 安男

山内 安男 ヤマウチ ヤスオ

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The polarized localization of p62 and NBR1 in cathepsin D-deficient neurons is involved in selective autophagyPrincipal Investigator

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神経軸索におけるタンパク分解機構とその破綻Principal Investigator

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Proteolysis in neuronal axons and its impairmentPrincipal Investigator

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Genetic study of molecular characteristic of autophagy-related proteins LC3A and LC3BPrincipal Investigator

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Searching for novel Dnase executing autophagic cell death.Principal Investigator

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脂肪滴形成へのオートファジーの関与についてPrincipal Investigator

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Molecular mechanisms of autophagic neuron deathPrincipal Investigator

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Uchiyama Yasuo 内山安男

UCHIYAMA Yasuo 内山安男

山内安男ヤマウチヤスオ