Akimoto Jiro 秋元治朗

Researcher Number	10212440
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2021: 東京医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Neurosurgery Except Principal Investigator Neurology / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 光線力学的療法 / 悪性脳腫瘍 / 光感受性物質 / 半導体レーザ / 治療効果増強 / 原発性悪性脳腫瘍 / レーザー治療 / 悪性グリオーマ / 悪性髄膜腫 / 悪性髄膜腫に対する光線力学的治療 … More / 悪性グリオーマに対する光線力学的治療 / 光線力学的療法と化学療法の相乗効果 / 一重項酸素 / アポトーシス / 脳腫瘍幹細胞 / 光化学反応 / 悪性神経膠腫 / Photodynamic therapy / Photosensitizer / M2 macrophage / Malignant brain tumor / Malignant glioma / Mannose receptor / Photoimmunotherapy / 糖鎖結合クロリン / 癌 / 脳神経疾患 / 病理学 / 臨床 … More Except Principal Investigator 14-3-3蛋白 / HMGB1 / Beclin1 / オートファジ－ / ＴＤＰ-43 / オ－トファジ－ / Beclin-1 / 頸動脈プラ－ク / 神経細胞死 / １４－３－３蛋白 / ＨＭＧＢ1 / Ｂｅｃｌｉｎ1 / 脳梗塞 / レビ－小体型認知症 / 血栓 / 頸動脈 / リン酸化TDP43 / 筋萎縮性側索硬化症 / Beclin 1 / アルツハイマ－病 / 血管性認知症 / 脳血管障害 / 頚動脈プラ-ク / リン酸化TDP-43 / Rubicon / beclin1 / BRCA1 / 脳動脈硬化 / オートファーゴソーム / TDP-43 / 14-3-3タンパク / マクロファ-ジ / 動脈硬化 / 内頚動脈プラ-ク / 分子制御された細胞死 / 認知症 / 分子制御細胞死 Less

Comprehensive study of "molecular-controlled cell death and autophagy" in dementia and cerebrovascular disease in the elderly
- Principal Investigator
  
  TAKAHIKO UMAHARA
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tokyo Medical University
Development of photoimmunotherapy using novel photosensitizer for malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  秋元治朗
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Medical University
Analysis of neuronal death control target 14-3-3 protein / HMGB1 / Beclin1
- Principal Investigator
  
  Umahara Takahiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical University
Enhancement of the effect of photodynamic therapy for malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  Akimoto Jiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Medical University

All 2020 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent

[Book] 脳腫瘍取り扱い規約2018
- Author(s)
  秋元治朗
- Total Pages
  221
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-17K10875
[Book] PDT実践ガイド2017
- Author(s)
  秋元治朗
- Total Pages
  180
- Publisher
  MEDICAL VIEW社
- Data Source
  KAKENHI-PROJECT-17K10875
[Book] 脳神経外科診療プラクテイス：グリオーマ治療のDecision Making2016
- Author(s)
  秋元治朗
- Total Pages
  314
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26462191
[Book] レザフィリンとPhotodynamic therapy(PDT)2015
- Author(s)
  秋元治朗
- Total Pages
  8
- Publisher
  MEDICAL REVIEW
- Data Source
  KAKENHI-PROJECT-26462191
[Book] クリ二シアン2014
- Author(s)
  秋元治朗
- Total Pages
  134
- Publisher
  エーザイ株式会社
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] Frontotemporal dementia-associated protein "phosphorylated TDP-43" localizes to atherosclerotic lesions of human carotid and main cerebral arteries2020
- Author(s)
  Umahara T, Uchihara T, Hirao K, Shimizu S, Hashimoto T, Akimoto J, Kohno M, Hanyu H.
- Journal Title
  
  Histol Histopathol
  
  Volume: 35 Pages: 159-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07426
[Journal Article] グリオーマに対する追加治療　III 光線力学的治療2018
- Author(s)
  秋元治朗
- Journal Title
  
  癌と化学療法
  
  Volume: 45 Pages: 933-937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10875
[Journal Article] 原発性悪性脳腫瘍の光線力学的診断と治療2018
- Author(s)
  秋元治朗
- Journal Title
  
  光アライアンス
  
  Volume: 29 Pages: 37-39
- NAID
  40021427552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10875
[Journal Article] Photodynamic therapy using talaporfin sodium induces heme oxygenate-1 expression in rat meningioma KMY-J cells2018
- Author(s)
  Takahashi T, Suzuki S, Misawa S, Akimoto J, Shinoda Y, Fujiwara Y
- Journal Title
  
  J Toxicol Sci
  
  Volume: 43 Pages: 353-358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10875
[Journal Article] 原発性悪性脳腫瘍の光線力学的診断(PDD)と治療(PDT)2017
- Author(s)
  秋元治朗
- Journal Title
  
  OPTRONICS
  
  Volume: 423 Pages: 60-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10875
[Journal Article] Comparative photodynamic therapy cytotoxicity of mannose-conjugated chlorin and talaporfin sodium in cultured human and rat cells.2017
- Author(s)
  Shinoda Y, Takahashi T, Akimoto J, Ichikawa M, Yamasaki H, Narumi A, Yano S, Fujiwara Y
- Journal Title
  
  J Toxicol Sci
  
  Volume: 42 Pages: 111-119
- NAID
  130005286650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10875
[Journal Article] Photodynamic Therapy for Malignant Brain Tumors2016
- Author(s)
  Akimoto J
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 56 Issue: 4 Pages: 151-157
- DOI
  10.2176/nmc.ra.2015-0296
- NAID
  130005145493
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 原発性悪性脳腫瘍に対する光線力学的療法の確立2016
- Author(s)
  秋元治朗
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 74 Pages: 21-28
- NAID
  120006576103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 膠芽腫に対する光線力学的療法2015
- Author(s)
  秋元治朗
- Journal Title
  
  癌と化学療法
  
  Volume: 42 Pages: 678-682
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 悪性脳腫瘍に対する光線力学的療法の開発と実践2015
- Author(s)
  秋元治朗
- Journal Title
  
  日本獣医麻酔外科学雑誌
  
  Volume: 46 Pages: 112-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 原発性悪性脳腫瘍に対する光線力学的療法(PDT)2015
- Author(s)
  秋元治朗
- Journal Title
  
  Pharma Medica
  
  Volume: 33 Pages: 111-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] Possibility and Challenge of Cancer Therapy using combination products with drug and device- Insight fro experiences of investigator-initiated clinical trial for malignant brain tumors by photodynamic therapy using Talaporfin and PDT laser.2015
- Author(s)
  Muragaki Y, Maruyama T, Ikuta S, Akimoto J, Iseki H
- Journal Title
  
  DRUG DELIVERY SYSTEM
  
  Volume: 30 Pages: 226-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium2014
- Author(s)
  Miki Y, Akimoto J, Omata H, Hiranuma M, Hironaka C, Fujiwara Y, Beppu M
- Journal Title
  
  Photodiagnosis Photodynamic Therapy
  
  Volume: 11 Pages: 556-564
- DOI
  10.1016/j.pdpdt.2014.09.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 悪性脳腫瘍に対する光線力学的治療2014
- Author(s)
  秋元治朗
- Journal Title
  
  東京都医師会雑誌
  
  Volume: 67 Pages: 16-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] Effect of talaporfin sodium-mediated photodynamic therapy on cell death modalities in human glioblastoma T98G cells2014
- Author(s)
  Miki Y, Akimoto J, Hiranuma M, Fujiwara Y
- Journal Title
  
  Journal of Toxicological Science
  
  Volume: 39 Pages: 821-827
- NAID
  130004704488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462191
[Journal Article] 光線力学的治療を施行した初発膠芽腫例2014
- Author(s)
  秋元治朗
- Journal Title
  
  脳神経外科速報
  
  Volume: 24 Pages: 54-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462191
[Patent] 光線力学的療法用遮光剤2017
- Inventor(s)
  ユフ精器株式会社、秋元治朗
- Industrial Property Rights Holder
  ユフ精器株式会社、秋元治朗
- Filing Date
  2017
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] Grade II, III髄膜腫に対する光線力学的療法2017
- Author(s)
  秋元治朗、深見真二郎、市川恵、永井健太、須田智裕、河野道宏
- Organizer
  第22回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] 初発膠芽腫に対する光線力学的療法の治療上乗せ効果～単施設内比較研究2017
- Author(s)
  秋元治朗、深見真二郎、市川恵、永井健太、須田智裕、河野道宏
- Organizer
  第76回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] Photodynamic therapy for malignant brain tumors using talaporfin sodium2017
- Author(s)
  Akimoto J
- Organizer
  Asian symposium of Euro Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] Photodynamic therapy for malignant brain tumors using talaporfin sodium2017
- Author(s)
  AKimoto J
- Organizer
  World Congress of International Photodynamic Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] 原発性悪性脳腫瘍の摘出術におけるレザフィリンによる蛍光診断2017
- Author(s)
  秋元治朗、深見真二郎、市川恵、永井健太、須田智裕、河野道宏
- Organizer
  第13回日本脳神経外科光線力学学会
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] 光線力学的療法後の腫瘍制御効果を剖検にて確認した２例2017
- Author(s)
  秋元治朗、深見真二郎、永井健太、須田智裕、河野道宏、原　由紀子、長尾俊孝
- Organizer
  第34回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-17K10875
[Presentation] 原発性悪性脳腫瘍に対する光線力学的療法（PDT：Photodynamic therapy):現場における課題と展望2016
- Author(s)
  秋元治朗、深見真二郎、市川恵、福原宏和、永井健太、須田智裕、河野道宏、
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対する光線力学的診断、治療～病理像との関連について～2016
- Author(s)
  秋元治朗、深見真二郎、市川恵、福原宏和、永井健太、須田智裕、河野道宏
- Organizer
  第34回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対する光線力学的療法(PDT)2016
- Author(s)
  秋元治朗
- Organizer
  第26回日本光線力学学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] Photodynamic therapy for malignant brain tumors2016
- Author(s)
  Akimoto J
- Organizer
  7th Japan-India Neurosurgical Conference
- Place of Presentation
  大阪
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対するPhotodynamic therapy (PDT)2015
- Author(s)
  秋元治朗
- Organizer
  第25回日本光線力学学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 脳外科領域における医師主導治験の経験2015
- Author(s)
  丸山隆志、村垣善浩、新田雅之、斎藤太一、秋元治朗、川俣貴一、伊関洋
- Organizer
  第25回日本光線力学学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対する光線力学的療法～その課題と展望2015
- Author(s)
  秋元治朗、深見真二郎、福原宏和、永井健太、須田智裕、河野道宏、市川恵、T.Hasan
- Organizer
  第36回日本レーザー医学会総会
- Place of Presentation
  栃木県文化センター
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対する光線力学的療法～その課題と展望2015
- Author(s)
  秋元治朗
- Organizer
  第74回日本脳神経外科学会総会
- Place of Presentation
  札幌文化教育会館
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 温故創新：本邦初の複合型医師主導治験を終えて2015
- Author(s)
  秋元治朗
- Organizer
  第17回脳教カンファレンス
- Place of Presentation
  ホテル森の風　立山
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 原発性悪性脳腫瘍に対する光線力学的療法2015
- Author(s)
  秋元治朗
- Organizer
  中四国PDT講習会
- Place of Presentation
  シェラトン広島
- Year and Date
  2015-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] Photodynamic therapy2015
- Author(s)
  秋元治朗
- Organizer
  第20回日本脳腫瘍の外科学会
- Place of Presentation
  名古屋観光ホテル
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 悪性脳腫瘍に対する光線力学的療法の開発と実践2015
- Author(s)
  秋元治朗
- Organizer
  第90回日本獣医麻酔外科学会
- Place of Presentation
  大宮ソニックシテイ
- Year and Date
  2015-06-21
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 悪性脳腫瘍に対する光線力学療法のトレーニングコース2014
- Author(s)
  秋元治朗、丸山隆志、村垣善浩、生田聡子、伊関洋、佐藤俊一、川瀬悠樹、峰久次郎、山田新、大塚正彦
- Organizer
  第24回日本光線力学学会学術講演会
- Place of Presentation
  浜松
- Year and Date
  2014-06-29
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 保険承認後にPDTを施行した悪性グリオーマの2例2014
- Author(s)
  秋元治朗、深見真二郎、市川恵、福原宏和、須田智裕、河野道宏
- Organizer
  第10回日本脳神経外科光線力学学会
- Place of Presentation
  浜松
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] Talaporfin sodiumとTemozolomideの同時投与はヒトグリオーマ細胞に対するPDT効果を増強する2014
- Author(s)
  秋元治朗、深見真二郎、市川恵、福原宏和、須田智裕、河野道宏、三木雄一、藤原泰之
- Organizer
  第10回日本脳神経外科光線力学学会
- Place of Presentation
  浜松
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 悪性脳腫瘍に対する光線力学的治療～All JapanからGlobal Standardへ～2014
- Author(s)
  秋元治朗
- Organizer
  第49回大分脳腫瘍懇話会
- Place of Presentation
  大分
- Year and Date
  2014-04-05
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 悪性脳腫瘍に対する光線力学療法2014
- Author(s)
  秋元治朗
- Organizer
  第2６回脳神経外科学臨床講座
- Place of Presentation
  東京
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] 光線力学的治療2014
- Author(s)
  秋元治朗、村垣善浩、伊関洋、丸山隆志、生田聡子、金子貞男、松村明、黒岩敏彦、嘉山孝正
- Organizer
  第73回日本脳神経外科学会総会
- Place of Presentation
  東京
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] Phase II clinical study on intraoperative photodynamic therapy in pathients with malignant brain t2014
- Author(s)
  J Akimoto, T Maruyama, Y Muragaki, S Ikuta, H Ikuta, S Kaneko, T Kuroiwa, T Kayama
- Organizer
  The 5th Asian joint PDT symposium
- Place of Presentation
  浜松市
- Year and Date
  2014-06-29
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] オールジャパンで臨んだ悪性脳腫瘍に対する光線力学的治療の保険適応拡大2014
- Author(s)
  秋元治朗
- Organizer
  第68回日本口腔科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-05-08
- Invited
- Data Source
  KAKENHI-PROJECT-26462191
[Presentation] All Jaanで臨んだ悪性脳腫瘍に対する光線力学的治療(PDT)の保険適応拡大
- Author(s)
  秋元治朗、會沢勝夫、河野道宏、丸山隆志、村垣善浩、生田聡子、伊関洋、嘉山孝正、松村明、金子貞男、黒岩敏彦
- Organizer
  第14回脳神経外科手術と機器学会
- Place of Presentation
  福岡
- Year and Date
  2014-04-18 – 2014-04-19
- Data Source
  KAKENHI-PROJECT-26462191

1. Umahara Takahiko (70266477)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 羽生春夫 (10228520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 清水聰一郎 (10385031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 橋本孝朗 (60266517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 宮澤啓介 (50209897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 赫寛雄 (70307338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 織田順 (60459500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 丸山隆志 (40301543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 平尾健太郎 (40516639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 河野道宏 (50718707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Akimoto Jiro 秋元 治朗

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Comprehensive study of "molecular-controlled cell death and autophagy" in dementia and cerebrovascular disease in the elderly

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Development of photoimmunotherapy using novel photosensitizer for malignant brain tumorsPrincipal Investigator

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Analysis of neuronal death control target 14-3-3 protein / HMGB1 / Beclin1

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Enhancement of the effect of photodynamic therapy for malignant brain tumorsPrincipal Investigator

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[Book] 脳腫瘍取り扱い規約2018

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[Book] PDT実践ガイド2017

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[Book] 脳神経外科診療プラクテイス：グリオーマ治療のDecision Making2016

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[Book] レザフィリンとPhotodynamic therapy(PDT)2015

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[Book] クリ二シアン2014

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[Journal Article] Frontotemporal dementia-associated protein "phosphorylated TDP-43" localizes to atherosclerotic lesions of human carotid and main cerebral arteries2020

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[Journal Article] グリオーマに対する追加治療 III 光線力学的治療2018

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[Journal Article] 原発性悪性脳腫瘍の光線力学的診断と治療2018

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[Journal Article] Photodynamic therapy using talaporfin sodium induces heme oxygenate-1 expression in rat meningioma KMY-J cells2018

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[Journal Article] 原発性悪性脳腫瘍の光線力学的診断(PDD)と治療(PDT)2017

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[Journal Article] Comparative photodynamic therapy cytotoxicity of mannose-conjugated chlorin and talaporfin sodium in cultured human and rat cells.2017

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[Journal Article] Photodynamic Therapy for Malignant Brain Tumors2016

Akimoto Jiro 秋元治朗

[Journal Article] グリオーマに対する追加治療　III 光線力学的治療2018