Watanabe Yasuo 渡辺泰男

… Alternative Names

WATANABE Yasuo 渡邊泰男

渡辺泰男ワタナベヤスオ

Less

Researcher Number	10273228
Other IDs
External Links
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 昭和薬科大学, 薬学部, 教授 2009 – 2011: Showa Pharmaceutical University, 薬学部, 教授 2001 – 2002: 香川医科大学, 医学部, 助教授 1997 – 2000: 名古屋大学, 医学部, 講師 1995 – 1997: 名古屋大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Neurochemistry/Neuropharmacology / Functional biochemistry / General medical chemistry / Neurochemistry/Neuropharmacology Except Principal Investigator General pharmacology / Neurosurgery / Basic Section 43030:Functional biochemistry-related / Circulatory organs internal medicine / Biological Sciences
Keywords	Principal Investigator カルモデュリンキナーゼ / dephosphorylation / phosphorylation / calmodulin kinase / neuronal NO synthase / 活性制御 / 神経細胞 / リン酸化 / 神経型一酸化窒素合成酵素 / activation mechanism … More / calcium signal / 一酸化窒素合成酵素 / カルシウム情報伝達 / 栄養飢餓 / 細胞老化 / 活性イオウ分子 / シスタチオニンγ-リアーゼ（CSE） / 細胞遊走能 / MAPキナーゼ / シスタチオニンγ-リアーゼ(CSE) / 活性イオウ / 血清飢餓 / structure biology / hippocampus / ischemia / calmodulin / calcium / 脱リン酸化反応 / リン酸部位特異的認識抗体 / CaMキナーゼ / 神経型NO合成酵素 / 構造生物学 / 海馬神経細胞 / 虚血シグナル / リン酸化・脱リン酸化 / カルシウム・カルモデュリン / neuronal cell / structure and function / リン酸化抗体 / リン酸化部位 / カルシウム情報ネットワーク / 活性制御機構 / 脱リン酸化 / 構造活性相関 / molecular pharmacology / cell biology / molecular biology / inactive mutant / NO synthase / CaM dependent enzyme / リン酸化による機能制御 / 非活性型ミュータントNOS / 一酸化窒素合成酵素(NOS) / 分子薬理学 / 細胞生物学 / 分子生物学 / 活性化メカニズム / 非活性型ミュータント / カルモデュリン依存性酵素 / 酸化ストレス / 一酸化窒素 / グルタチオン化 / レドックス / 細胞内情報伝達 … More Except Principal Investigator カルシウムシグナリング / 阻害剤 / CALMODULIN / カルモデュリン / カルサイクリン / 慢性硬膜下血腫 / 多量体 / TIM-063 / 細胞内カルシウム情報伝達 / キナーゼ阻害剤 / 酵素阻害剤 / 基質認識機構 / 分子間相互作用 / Ca2+シグナル伝達 / タンパク質リン酸化酵素 / 酵素阻害薬 / 細胞内カルシウム信号系 / 精子 / リン酸化反応 / 細胞内カルシウム / 細胞内情報伝達 / CaMキナーゼカスケード / calmodulin / キナーゼ / タンパク質リン酸化反応 / 細胞内カルシウムシグナル伝達 / CaMKK / eotaxin-3 / 好酸球 / Adeno Virus / Atherosclerosis / Gene Therapy / Inducible nitric oxide synthase / Endothelial nitric oxide synthase / 構造機能解析 / 一酸化窒素合成酵素 / 血管内超音波 / 遺伝子導入 / 動脈硬化退縮 / 一酸化窒素 / アデノウイルス / 動脈硬化 / 遺伝子治療 / 誘導型NO合成酵素 / 内皮型NO合成酵素 / isopurine compounds / isoquinolinesulphonamide compounds / cdc2 kinase / cell cycle / protein kinase inhibitor / 分子プローブ / プロテインキナーゼ / イソプリン化合物 / イソキノリンスルホナミド化合物 / cdc2キナーゼ / 細胞周期 / プロテインキナーゼ阻害剤 / CALCYCLIN / DIABETES MELLITUS / INSULIN / PANCREATIC B-CELL / HORMONE SECRETION / CALCIUM-SIGNALLING / CALCIUM-BINDING PROTEINS / カルモジュリン / 糖尿病 / 膵B細胞 / インスリン / 内分泌 / カルシウム結合蛋白 / Computer simulation / Drug design / Structure-activity relationship / Tertiary structure / Inhibitor / Protein kinase / Intracellular signal transduction / 分子基礎理論 / 活性調節部位 / 有機合成 / 分子設計 / 特異的阻害剤 / コンピューターシュミレーション / 創薬 / 蛋白質立体構造 / 構造活性相関 / 蛋白質リン酸化酵素 / 細胞内シグナリング / PROTEIN KINASE CASCADES / CALMODULIN-DEPENDENT PROTEIN KINASE / CALCIUM SIGNAL TRANSDUCTION / 活性化メカニズム / カルモデュリンキナーゼV活性化因子 / カルモデュリンキナーゼV / カルモデュリン依存性キナーゼ / プロテインキナーゼカスケード / カルモデュリンキナーゼ / 3D-structure / NMR / Ca^<2+>-binding proteins / annexinXI / Calcyclin / 高次構造変換 / 細胞内局在 / NMR解析 / アネキシンXI / 高次構造 / 核磁気共鳴法 / カルシウム結合蛋白質 / アネキシン / autophagy / apoptosis / 抗酸化 / メタボローム / ケミカルバイオロジー / 代謝 / 活性酸素 Less

Development of inhibitors based on CaMKK-mediated signal transduction
- Principal Investigator
  
  Tokumitsu Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Okayama University
Regulation of cellular senescence via starvation-induced reactive sulfur species-signalPrincipal Investigator
- Principal Investigator
  
  Watanabe Yasuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa Pharmaceutical University
Clarification of eosinophilic chemoattractants in chronic subdural hematoma outer membrane
- Principal Investigator
  
  Osuka Koji
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Aichi Medical University
Polysulfur metabolome and regulation of anti-oxidative stress responses
- Principal Investigator
  
  Akaike Takaaki
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Role of apoptosis in the spontaneous disappearance of chronic subdural hematoma
- Principal Investigator
  
  Osuka Koji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Aichi Medical University
Redox regulation of calmodulin kinase I in neuronsPrincipal Investigator
- Principal Investigator
  
  WATANABE Yasuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Showa Pharmaceutical University
Regulation of neuronal nitric oxide synthase via phosphorylation and dephosphorylation in neuronal cellsPrincipal Investigator
- Principal Investigator
  
  WATANABE yasuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kagawa Medical University
Structure and function analyses of neuronal nitric oxide synthasePrincipal Investigator
- Principal Investigator
  
  WATANABE Yasuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Novel calcium signaling pathways in cell cycle regulations
- Principal Investigator
  
  NIKI Ichiro, 日高弘義
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Investigation of Regression of Atherosclerotic Lesion through Regulation of Nitric Oxide Related Responses -Treatment by Gene Transfer of Nitric Oxide Synthase-
- Principal Investigator
  
  IGUCHI Akihisa
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University
The study of activation mechanism of neuronal NO synthasePrincipal Investigator
- Principal Investigator
  
  WATANABE Yasuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
NETWORK OF CALCIUM-BINDING PROTEINS IN THE SIGNAL CASCADE
- Principal Investigator
  
  NIKI Ichiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  NAGOYA UNIVERSITY
Nuclear magnetic resonance studies of calcyclin and annexin XI.
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
ELUCIDATION OF THE INTRACELLULAR CALCIUM SIGNAL TRANSDUCTION WITH THE MOLECULAR PHARMACOLOGICAL APPROARCH
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  NAGOYA UNIVERSITY
Molecular basis and generation of new compounds for probing phosphorylation-mediated signaling pathways
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University

All 2021 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] みてわかる薬学　図解　薬理学2015
- Author(s)
  渡邊泰男
- Total Pages
  873
- Publisher
  南山堂（東京都）
- Data Source
  KAKENHI-PLANNED-26111008
[Journal Article] Sequential Expression of Chemokines in Chronic Subdural Hematoma Fluids after Trepanation Surgery2021
- Author(s)
  Osuka Koji、Ohmichi Yusuke、Ohmichi Mika、Nakura Takahiro、Iwami Kenichiro、Watanabe Yasuo、Miyachi Shigeru
- Journal Title
  
  Journal of Neurotrauma
  
  Volume: 38 Issue: 14 Pages: 1979-1987
- DOI
  10.1089/neu.2020.7401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-21K16644
[Journal Article] Sequential expression of neutrophil chemoattractants in cerebrospinal fluid after subarachnoid hemorrhage2021
- Author(s)
  Osuka Koji、Watanabe Yasuo、Suzuki Chiharu、Iwami Kenichiro、Miyachi Shigeru
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 357 Pages: 577610-577610
- DOI
  10.1016/j.jneuroim.2021.577610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-21K16644
[Journal Article] Persulfide Signaling in Stress-Initiated Calmodulin Kinase Response2020
- Author(s)
  Takata Tsuyoshi、Araki Shoma、Tsuchiya Yukihiro、Watanabe Yasuo
- Journal Title
  
  Antioxidants & Redox Signaling
  
  Volume: 33 Issue: 18 Pages: 1308-1319
- DOI
  10.1089/ars.2020.8138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-18K11083
[Journal Article] Coordination between Calcium/Calmodulin-Dependent Protein Kinase II and Neuronal Nitric Oxide Synthase in Neurons2020
- Author(s)
  Araki Shoma、Osuka Koji、Takata Tsuyoshi、Tsuchiya Yukihiro、Watanabe Yasuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 21 Pages: 7997-7997
- DOI
  10.3390/ijms21217997
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-18K11083
[Journal Article] Expression of high mobility group B1 and toll-like receptor-nuclear factor κB signaling pathway in chronic subdural hematomas2020
- Author(s)
  Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Iwami Kenichiro、Miyachi Shigeru、Takayasu Masakazu
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 6 Pages: e0233643-e0233643
- DOI
  10.1371/journal.pone.0233643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10853
[Journal Article] Oxidative Stress Orchestrates MAPK and Nitric-Oxide Synthase Signal2020
- Author(s)
  Takata Tsuyoshi、Araki Shoma、Tsuchiya Yukihiro、Watanabe Yasuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 22 Pages: 8750-8750
- DOI
  10.3390/ijms21228750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-18K11083
[Journal Article] Reactive sulfur species impair Ca2+/calmodulin-dependent protein kinase II via polysulfidation2019
- Author(s)
  Araki Shoma、Takata Tsuyoshi、Tsuchiya Yukihiro、Watanabe Yasuo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 2 Pages: 550-555
- DOI
  10.1016/j.bbrc.2018.11.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11083, KAKENHI-PROJECT-18K14853
[Journal Article] The active-site cysteine residue of Ca2+/calmodulin-dependent protein kinase I is protected from irreversible modification via generation of polysulfidation2019
- Author(s)
  Takata Tsuyoshi、Tsukuda Ayaka、Tsuchiya Yukihiro、Akaike Takaaki、Watanabe Yasuo
- Journal Title
  
  Nitric Oxide
  
  Volume: 86 Pages: 68-75
- DOI
  10.1016/j.niox.2019.02.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11083, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18K07099, KAKENHI-PROJECT-18K14853
[Journal Article] Redox regulation of Ca2+/calmodulin-dependent protein kinase IV via oxidation of its active-site cysteine residue2019
- Author(s)
  Takata Tsuyoshi、Kimura Jun、Ihara Hideshi、Hatano Naoya、Tsuchiya Yukihiro、Watanabe Yasuo
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 130 Pages: 99-106
- DOI
  10.1016/j.freeradbiomed.2018.10.440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11083, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-18K14853
[Journal Article] Expression of Autophagy Signaling Molecules in the Outer Membranes of Chronic Subdural Hematomas2019
- Author(s)
  Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Aoyama Masahiro、Takeuchi Mikinobu、Takayasu Masakazu
- Journal Title
  
  Journal of Neurotrauma
  
  Volume: 36 Issue: 2 Pages: 403-407
- DOI
  10.1089/neu.2018.5626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853
[Journal Article] 酸化還元状態　Sーグルタチオン化2018
- Author(s)
  高田剛・土屋幸弘・渡邊泰男
- Journal Title
  
  生体の科学
  
  Volume: 69 Pages: 442-443
- Data Source
  KAKENHI-PROJECT-18K11083
[Journal Article] Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser1412 in the dentate gyrus of the rat brain.2018
- Author(s)
  K Wada, K Osuka, Y Watanabe, N Usuda, M Fukasawa, Y Araki, S Okamoto, T Wakabayashi
- Journal Title
  
  Nitric Oxide
  
  Volume: 81 Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853
[Journal Article] Involvement of nitric oxide/reactive oxygen species signaling via 8-nitro-cGMP formation in 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells and rat cerebellar granule neurons2018
- Author(s)
  Masuda Kumiko、Tsutsuki Hiroyasu、Kasamatsu Shingo、Ida Tomoaki、Takata Tsuyoshi、Sugiura Kikuya、Nishida Motohiro、Watanabe Yasuo、Sawa Tomohiro、Akaike Takaaki、Ihara Hideshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 3 Pages: 2165-2170
- DOI
  10.1016/j.bbrc.2017.12.088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K17583, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-16H05044, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20876, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-18H05293
[Journal Article] Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser 1412 in the dentate gyrus of the rat brain2018
- Author(s)
  Wada Kentaro、Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Fukasawa Motoaki、Araki Yoshio、Okamoto Sho、Wakabayashi Toshihiko
- Journal Title
  
  Nitric Oxide
  
  Volume: in press Pages: 67-74
- DOI
  10.1016/j.niox.2017.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-26462174
[Journal Article] Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics2017
- Author(s)
  Akaike Takaaki、、、Nishida Motohiro（4）、、、、、、Fujii Shigemoto（20）、、、Motohashi Hozumi（26）
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1177-1177
- DOI
  10.1038/s41467-017-01311-y
- NAID
  120007134656
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K15408, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26110003, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876, KAKENHI-PLANNED-26116005, KAKENHI-PROJECT-16H05092
[Journal Article] Expression of Caspase Signaling Components in the Outer Membranes of Chronic Subdural Hematomas2017
- Author(s)
  Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Aoyama Masahiro、Iwami Kenichiro、Takeuchi Mikinobu、Watabe Takeya、Takayasu Masakazu
- Journal Title
  
  Journal of Neurotrauma
  
  Volume: 34 Issue: 22 Pages: 3192-3197
- DOI
  10.1089/neu.2017.5051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-26462174
[Journal Article] Superoxide generation from nNOS splice variants and its potential involvement in redox signal regulation2017
- Author(s)
  Ihara H, Kitamura A, Kasamatsu S, Ida T, Kakihana Y, Tsutsuki H, Sawa T, Watanabe Y, Akaike T.
- Journal Title
  
  Biochem J
  
  Volume: 474 Issue: 7 Pages: 1149-1162
- DOI
  10.1042/bcj20160999
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20876
[Journal Article] 1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides2017
- Author(s)
  Abiko Y, Sha L, Shinkai Y, Unoki T, Luong NC, Tsuchiya Y, Watanabe Y, Hirose R, Akaike T, Kumagai Y.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 104 Pages: 118-128
- DOI
  10.1016/j.freeradbiomed.2016.12.047
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15K18994, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-16K18920, KAKENHI-PROJECT-17K15489, KAKENHI-PROJECT-15K08042
[Journal Article] Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion.2017
- Author(s)
  Takahashi N, Wei FY, Watanabe S, Hirayama M, Ohuchi Y, Fujimura A, Kaitsuka T, Ishii I, Sawa T, Nakayama H, Akaike T, Tomizawa K.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 45 Issue: 1 Pages: 435-445
- DOI
  10.1093/nar/gkw745
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-16K15194, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-16K18989, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-15K11296, KAKENHI-PROJECT-16H05107
[Journal Article] Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide2017
- Author(s)
  K. Hanaoka, K. Sasakura, Y. Suwanai, S. Toma-Fukai, K. Shimamoto, Y. Takano, N. Shibuya, T. Terai, T. Komatsu, T. Ueno, Y. Ogasawara, Y. Tsuchiya, Y. Watanabe, H. Kimura, C. Wang, M. Uchiyama, H. Kojima, T. Okabe, Y. Urano, T. Shimizu, T. Nagano
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 40227-40227
- DOI
  10.1038/srep40227
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-14F04908, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15K18994, KAKENHI-PROJECT-26460352, KAKENHI-PROJECT-16K15123, KAKENHI-PROJECT-17K08331, KAKENHI-PROJECT-17K08613, KAKENHI-PROJECT-17H06173, KAKENHI-PROJECT-26460115
[Journal Article] Reactive sulfur species inactivate Ca2+/calmodulin-dependent protein kinase IV via S-polysulfidation of its active-site cysteine residue2017
- Author(s)
  Takata T, Ihara H, Hatano N, Tsuchiya Y, Akaike T, Watanabe Y.
- Journal Title
  
  Biochem J
  
  Volume: 474 Issue: 15 Pages: 2547-2562
- DOI
  10.1042/bcj20170092
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208
[Journal Article] Activation of Nuclear Factor-kappa B in Endothelial Cells of Chronic Subdural Hematoma Outer Membranes.2017
- Author(s)
  Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Takeuchi M, Takayasu M.
- Journal Title
  
  Neurosurgery
  
  Volume: 80 Issue: 4 Pages: 571-578
- DOI
  10.1093/neuros/nyw100
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-17K10853
[Journal Article] Quantitative determination of polysulfide in albumins, plasma proteins and biological fluid samples using a novel combined assays approach2017
- Author(s)
  keda, M. Ishima, Y. Shibata, A. Chuang, V. T. G. Sawa, T. Ihara, H. Watanabe, H. Xian, M. Ouchi, Y. Shimizu, T. Ando, H. Ukawa, M. Ishida, T. Akaike, T. Otagiri, M. Maruyama, T.
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 969 Pages: 18-25
- DOI
  10.1016/j.aca.2017.03.027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-17K19205, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-16K15208
[Journal Article] Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas.2017
- Author(s)
  Osuka K, Watanabe Y, Usuda N, Aoyama M, Iwami K, Takeuchi M, Watabe T, Takayasu M.
- Journal Title
  
  J Neurotrauma
  
  Volume: in press Issue: 11 Pages: 1996-2000
- DOI
  10.1089/neu.2016.4623
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-17K10853
[Journal Article] Activation of STAT3 in endothelial cells of chronic subdural hematoma outer membranes.2016
- Author(s)
  Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Watabe T, Takayasu M
- Journal Title
  
  World Neurosurg
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462174
[Journal Article] Activation of signal transducer and activator of transcription 3 in endothelial cells of chronic subdural hematoma outer membranes2016
- Author(s)
  Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Watabe T, Takayasu M.
- Journal Title
  
  World Neurosurg
  
  Volume: 91 Pages: 376-382
- DOI
  10.1016/j.wneu.2016.04.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
[Journal Article] Regulation of calcium signals via redox modification2016
- Author(s)
  渡邊泰男
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 5 Pages: 285-289
- DOI
  10.1254/fpj.147.285
- NAID
  130005150962
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111008
[Journal Article] Expression of Mitogen-Activated Protein Kinases in Chronic Subdural Hematoma Outer Membranes.2015
- Author(s)
  Aoyama M, Osuka K, Usuda N, Watanabe Y, Kawaguchi R, Nakura T, Takayasu M
- Journal Title
  
  J Neurotrauma
  
  Volume: 32 Issue: 14 Pages: 1064-1070
- DOI
  10.1089/neu.2014.3594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-25504016, KAKENHI-PLANNED-26111008
[Journal Article] RSSの生合成系とタンパク質機能制御2015
- Author(s)
  渡邊泰男、石井　功、蕨　栄治.
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 372-376
- Data Source
  KAKENHI-PLANNED-26111008
[Journal Article] Formation of Sulfur Adducts of N-Acetyl-p-benzoquinoneimine, an Electrophilic Metabolite of Acetaminophen in Vivo: Participation of Reactive Persulfides.2015
- Author(s)
  Abiko Y., Ishii I., Kamata S., Tsuchiya Y., Watanabe Y., Ihara H., Akaike T., Kumagai Y.
- Journal Title
  
  Chem. Res. Toxicol.
  
  Volume: 28 Issue: 9 Pages: 1796-1802
- DOI
  10.1021/acs.chemrestox.5b00245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18994, KAKENHI-PUBLICLY-15H01392, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15J03367, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-25460072, KAKENHI-PROJECT-26670207, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25253020
[Journal Article] Increased ICP promotes CaMKII-mediated phosphorylation of neuronal NOS at Ser847 in the hippocampus immediately after subarachnoid hemorrhage2015
- Author(s)
  Makino K, Osuka K, Watanabe Y, Usuda N, Hara M, Aoyama M, Takayasu M, Wakabayashi T.
- Journal Title
  
  Brain Res
  
  Volume: 1616 Pages: 19-25
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26111008
[Journal Article] Increased ICP promotes CaMKII-mediated phosphorylation of neuronal NOS at Ser⁸⁴⁷ in the hippocampus immediately after subarachnoid hemorrhage.2015
- Author(s)
  Makino K, Osuka K, Watanabe Y, Usuda N, Hara M, Aoyama M, Takayasu M, Wakabayashi T
- Journal Title
  
  Brain Res
  
  Volume: 1616 Pages: 19-25
- DOI
  10.1016/j.brainres.2015.04.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-25504016
[Journal Article] Redox signal regulation via nNOS phosphorylation at Ser847 in PC12 cells and rat cerebellar granule neurons.2014
- Author(s)
  Kasamats S, Watanabe Y, Sawa T, Akaike T, Ihara H.
- Journal Title
  
  Biochem. J.
  
  Volume: 459 Issue: 2 Pages: 251-263
- DOI
  10.1042/bj20131262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25430069, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670207
[Journal Article] Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.2014
- Author(s)
  Ida T, Sawa T, Ihara H, Tsucr iya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S. Matsunaga T, Yamamoto M, Ono K, Devarie-Baez N O, Xian M, Fukuto J M, Akaike T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: (印刷中) Issue: 21 Pages: 7606-7611
- DOI
  10.1073/pnas.1321232111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24590527, KAKENHI-PROJECT-24790263, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-25870549, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670131, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26670207
[Journal Article] Expression of suppressor of cytokine signaling 3 in cerebrospinal fluid after subarachnoid hemorrhage2014
- Author(s)
  Osuka K, Watanabe Y, Aoyama M, Nakura T, Matsuo N, Takayasu M.
- Journal Title
  
  J Neuroinflammation
  
  Volume: 11 Issue: 1 Pages: 142-142
- DOI
  10.1186/s12974-014-0142-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
[Journal Article] Eotaxin-3 activates Smad through the TGF-β1 pathway in chronic subdural hematoma outer membranes.2014
- Author(s)
  Osuka K, Watanabe Y, Usuda N, Aoyama M, Takeuchi M, Takayasu M.
- Journal Title
  
  J Neurotrauma
  
  Volume: 31 Issue: 16 Pages: 1451-1456
- DOI
  10.1089/neu.2013.3195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25504016, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
[Journal Article] Adiponectin activates endothelial nitric oxide synthase through AMPK signaling after subarachonid hemorrhage2012
- Author(s)
  Osuka K., Watanabe Y., Yasuda M., Takayasu M
- Journal Title
  
  Neurosci. Lett
  
  Volume: 514 Pages: 2-5
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22230897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Activation of STAT1 in neurons followinjury in mice2011
- Author(s)
  Osuka K., Watanabe Y., Usuda N., Atsuzawa K., Yasuda M., Aoshima C., Wakabayashi T., Takayasu M
- Journal Title
  
  Neuroche. Res
  
  Volume: 36 Pages: 2236-2243
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21833847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Activation of PI3 kinase/Akt signaling in chronic subdural houter membranes2011
- Author(s)
  Funai M., Osuka K., Usuda N., Atsuzawa K., Inukai T., Yasuda M., Watanabe Y. Takayasu M
- Journal Title
  
  J. Neurotrauma
  
  Volume: 28 Pages: 1127-1131
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21309701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Calcium/calmodulin-dependent protein kinases as potential targets of nitric oxide Nitric Oxide2011
- Author(s)
  Takata T, Kimura J., Tsuchiya Y., Naito Y. Watanabe Y
- Volume
  25
- Pages
  145-152
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21255668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Hypothermia enhances the colocalization of calmodulin kinase IIαwith neuronal nitric oxide synthase in the hippocamfollowing cerebral ischemia2011
- Author(s)
  Hayashi S., Osuka K., Watanabe Y., Yasuda M., Takayasu M., Wakabayashi T
- Journal Title
  
  Neurosci. Lett
  
  Volume: 505 Pages: 228-232
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22015767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Two naturally occurring terpenes, dehydrocostuslactone and costunolide decrease intracellular GSH content and inhibit STAT3 activation2011
- Author(s)
  Butturini E., Cavalieri E., Carcereri de Prati, A., Darra E., Rigo A., Shoji K., MurayN., Yamazaki H., Watanabe Y., Suzuki H. Mariotto S
- Journal Title
  
  PLoS ONE
  
  Volume: 6(5) Pages: 20174-20174
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21625597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Oxidative stress activates STAT1 in basilar arteries after subarachnoid hemorrhage Brain Res2010
- Author(s)
  Osuka K., Watanabe Y., Usuda N., Atsuzawa K., Wakabayashi T., Takayasu M
- Volume
  1332
- Pages
  12-19
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20307504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Journal Article] Modification of Endothelial NitrSynthase through AMPK after Experimental Subarachnoid Hemorrhag J2009
- Author(s)
  Osuka K., Watanabe Y., Usuda N., Atsuzawa K., Yoshida J., Takayasu M
- Journal Title
  
  Neurotrauma
  
  Volume: 26 Pages: 1157-1165
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19226196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 血清飢餓によるシスタチオニン γ-リアーゼ発現誘導の意義2020
- Author(s)
  荒木笙馬、海老澤芳、土屋幸弘、渡邊泰男
- Organizer
  第20回日本NO学会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] レドックスセンサーとしてのシスタチオニン γ-リアーゼ2020
- Author(s)
  土屋幸弘、荒木笙馬、渡邊泰男
- Organizer
  第20回日本NO学会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] マクロファージのLPS応答における活性イオウ分子によるカルモデュリンキナーゼII活性制御2019
- Author(s)
  荒木笙馬、高田剛、土屋幸弘、渡邊泰男
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] PC12細胞におけるアセチルコリン信号系とその阻害薬としてのノビレチン2019
- Author(s)
  土屋幸弘、松下莉子、高田剛、居原秀、渡邊泰男
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] カルモデュリンキナーゼIに対する活性イオウ分子の生理的役割2019
- Author(s)
  岸康二郎、高田剛、土屋幸弘、赤池孝章、渡邊泰男
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] Persulfide signaling in LPS-initiated macrophage response2019
- Author(s)
  渡邊泰男
- Organizer
  1st International Conference on Persulfide and Sulfur Metabolism in Biology and Medicine Date
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] カルモデュリンキナーゼIのポリスルフィド化とその意義2019
- Author(s)
  高田剛、佃彩華、土屋幸弘、赤池孝章、渡邊泰男
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 活性イオウ分子によるマクロファージでのカルモデュリンキナーゼII活性制御2019
- Author(s)
  久保寺傑、荒木笙馬、高田剛、土屋幸弘、渡邊泰男
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 炎症応答における活性イオウ分子によるカルモデュリンキナーゼII活性制御2019
- Author(s)
  荒木笙馬、高田剛、土屋幸弘、渡邊泰男
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 抗コリン薬として働くノビレチン2019
- Author(s)
  岩田千宏、土屋幸弘、松下莉子、高田剛、居原秀、渡邊泰男
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] カルモデュリンキナーゼ群の活性イオウ分子応答性の差異2019
- Author(s)
  高田剛、土屋幸弘、赤池孝章、渡邊泰男
- Organizer
  第９２回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 活性イオウによるリン酸化シグナル制御2018
- Author(s)
  渡邊泰男
- Organizer
  第９１回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 部位特異的S-ポリスルフィド化修飾を介したカルモデュリンキナーゼII活性制御2018
- Author(s)
  荒木笙馬、高田剛、土屋幸弘、渡邊泰男
- Organizer
  第９１回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] REGULATION OF CALCIUM ION/CALMODULIN-DEPENDENT PROTEIN KINASE I BY S-POLYSULFIDATION2018
- Author(s)
  Tsuyoshi Takata, Yukihiro Tsuchiya, Yasuo Watanabe
- Organizer
  The 10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] NOによるによるシスタチオニンγ-リアーゼ活性制御2018
- Author(s)
  荒木笙馬、高田剛、土屋幸弘、渡邊泰男
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会　合同学術集会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] カルモデュリンキナーゼIの活性イオウ分子応答性の解明2018
- Author(s)
  高田剛、土屋幸弘、渡邊泰男
- Organizer
  第９１回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] REACTIVE SULFUR SPECIES INHIBIT Ca2+/ CALMODULIN DEPENDENT PROTEIN KINASE II ACTIVITY VIA SITE SPECIFIC S-POLYSULFIDATION2018
- Author(s)
  Shoma Araki, Tsuyoshi Takata, Yukihiro Tsuchiya, Yasuo Watanabe
- Organizer
  The 10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] REGULATION OF CYSTATHIONINE Γ-LYASE BY CYSTEINE HYDROPERSULFIDE2018
- Author(s)
  Yasuo Watanabe, Shoma Araki, Tsuyoshi Takata, Yukihiro Tsuchiya1, Takaaki Akaike
- Organizer
  The 10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 過酸化水素によるカルモデュリンキナーゼVの活性制御2018
- Author(s)
  高田剛、居原秀、土屋幸弘、渡邊泰男
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会　合同学術集会
- Data Source
  KAKENHI-PROJECT-18K11083
[Presentation] 活性システインパースルフィドのメタボロミクスとプロテオミクス2015
- Author(s)
  井田智章、居原　秀、澤　智裕、土屋幸弘、渡邊泰男、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章.
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  かごしま県民交流センター（鹿児島市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PLANNED-26111008
[Presentation] 活性システインパースルフィドのメタボロームおよびプロテオーム解析2015
- Author(s)
  井田智章、居原　秀、澤　智裕、土屋幸弘、渡邊泰男、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章.
- Organizer
  第15回日本NO学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PLANNED-26111008
[Presentation] カルモデュリンキナーゼIVはレドックスにより活性が制御される2012
- Author(s)
  土屋幸弘、高田剛、木村淳、渡邊泰男
- Organizer
  第85回日本薬理学会年会
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] カルモデュリンキナーゼの一酸化窒素による活性制御2012
- Author(s)
  高田剛、土屋幸弘、渡邊泰男
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NO、活性酸素でみるくも膜下出血の分子病態2011
- Author(s)
  大須賀浩二、高安正和、渡邊泰男
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NOの標的分子としてのカルモデュリンキナーゼ2011
- Author(s)
  渡邊泰男
- Organizer
  日本薬学会第131年会
- Place of Presentation
  グランシップ静岡
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] マウス海馬でのニコチンによるERK活性化におけるNOの関与2011
- Author(s)
  土屋幸弘、前田千春、宮本嘉明、居原秀、渡邊泰男
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 一酸化窒素信号系によるニコチン誘発性MAP kinaseファミリーの活性化2011
- Author(s)
  彦坂知佐、菊地明日香、梶原綾、土屋幸弘、居原秀、渡邊泰男
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] スルフェン化によるカルモデュリンキナーゼIVの活性制御機構五味渕優紀2011
- Author(s)
  木村淳、土屋幸弘、渡邊泰男
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NO信号系によるカルモデュリンキナーゼ活性制御機構2011
- Author(s)
  高田剛、池田未希、木村淳、土屋幸弘、渡邊泰男
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経型一酸化窒素合成酵素のSer847リン酸化は神経細胞における-酸化窒素一活性酸素種シグナリングを調節する2011
- Author(s)
  笠松真吾、澤智裕、渡邊泰男、赤池孝章、居原秀
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  山代温泉(石川)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経型一酸化窒素合成酵素のリン酸化による-酸化窒素/活性酸素種シグナル経路の調節機構の解析2011
- Author(s)
  笠松真吾、澤智裕、渡邊泰男、赤池孝章、居原秀
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(東京)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経におけるカルモデュリンキーゼレドックス応答性とその意義2010
- Author(s)
  渡邊泰男
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] カルモデュリンキナーゼIVのレドックスによる活性制御機構2010
- Author(s)
  木村淳, 土屋幸弘, 渡邊泰男
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] ニコチン誘発性P38活性化機構における一酸化窒素の関与2010
- Author(s)
  梶原綾, 彦坂知佐, 前田千春, 宮本嘉明, 土屋幸弘, 居原秀, 渡邊泰男
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NOによるCa2+/カルモデュリン依存性プロテインキナーゼIアイソフォームの活性制御2010
- Author(s)
  内藤康仁、山路晶子、遠山加奈子、渡邊泰男、佐々木泰治
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経型NO合成酵素恒常発現PC12細胞での薬物誘発細胞障害性に対するニコチンの効果2010
- Author(s)
  前田千春, 宮本嘉明, 土屋幸弘, 居原秀, 渡邊泰男
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NOによるCa2+/カルモデュリン依存性プロテインキナーゼIアイソフォームの活性制御2010
- Author(s)
  内藤康仁, 遠山加奈子, 山路晶子, 渡邊泰男, 田辺光男
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] Calcium/calmodulin-dependent protein kinases as potential targets of NO2010
- Author(s)
  Yasuo Watanabe
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto International Conference Center (Kyoto)(招待講演)
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] レドックスセンサーとしてのカルモデュリンキナーゼIの活性制御2010
- Author(s)
  高田剛, 土屋幸弘, 渡邊泰男
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] Superoxide generation from neuronanitric oxide synthase splice variants and its potential involvement in NO-ROS signaling2010
- Author(s)
  Hideshi Ihara, Ida Tomoaki, Sawa Tomohiro, Yasuo Watanabe, Takaaki Akaike
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] ニコチン誘発性ERKシグナリングにおける神経型一酸化窒素合成酵素の関与2010
- Author(s)
  酒井亮介、宮本嘉明、前田千春、神戸敏江、居原秀、渡邊泰男
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] グルタチオン化によるカルモデュリンキナーゼIの活性制御2010
- Author(s)
  高田剛、神戸敏江、宮本嘉明、波多野直哉、内藤康仁、宋涛、野崎直仁、渡邊泰男
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経型一酸化窒素合成酵素のリン酸化によるNO/ROS産生への影響2010
- Author(s)
  笠松真吾, 澤智裕, 渡邊泰男, 赤池孝章, 居原秀
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経におけるカルモデュリンキナーゼのレドックス応答性とその意義2010
- Author(s)
  渡邊泰男
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] Analysis of the uncoupling reaction of neuronal nitric oxide synthase2010
- Author(s)
  Shingo Kasamatsu, Yasuo Watanabe, Hideshi Ihara
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] Calcium/calmodulin-dependent protein kinases as potential targets of NO2010
- Author(s)
  Yasuo Watanabe
- Organizer
  The 6th InternatioConference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] ラットくも膜下出血モデルにおけるeNOS活性化について2009
- Author(s)
  渡邊泰男、大須賀浩二、若林俊彦、高安正和
- Organizer
  第9回日本NO学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 一酸化窒素による脳血管れん縮の分子病態2009
- Author(s)
  大須賀浩二、高安正和、渡邊泰男
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NOによるCa2+/Calmodulin-dependent protein kinase Iγの活性調節機構2009
- Author(s)
  山路晶子、佐々木泰治、渡邊泰男、内藤康仁
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 月桂樹由来テルペンのSTAT3活性化と抗腫瘍効果2009
- Author(s)
  Elena Butturini, Elisabetta Cavalieri, Elena Darra, Alessandra Carcereri de Prati, Sofia Mariotto, Kazuo Shoji, Yasuo Watanabe, Hisanori Suzuki
- Organizer
  第9回日本NO学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] ニコチン・シグナリングにおけるNO依存性レドックス制御2009
- Author(s)
  宮本嘉明、酒井亮祐、前田千春、神戸敏江、居原秀、渡邊泰男
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NOによるニコチン・シグナリングの活性制御2009
- Author(s)
  酒井亮祐、宮本嘉明、前田千春、神戸敏江、居原秀、渡邊泰男
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] カルモデュリンキナーゼIのグルタチオン化応答性の意義2009
- Author(s)
  神戸敏江、高田剛、宮本嘉明、波多野直哉、内藤康仁、宋涛、野崎直仁、渡邊泰男
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] ラットくも膜下出血モデルにおけるeNOS活性化について2009
- Author(s)
  渡邊泰男
- Organizer
  第9回日本NO学会
- Place of Presentation
  グランシップ(静岡)
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] グルタチオン化によるカルモデュリンキナーゼIの活性制御2009
- Author(s)
  渡邊泰男
- Organizer
  第9回日本NO学会
- Place of Presentation
  グランシップ(静岡)
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 神経型一酸化窒素合成酵素アンカップリング反応の解析2009
- Author(s)
  笠松真吾、渡邊泰男、居原秀
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 海馬でのニコチン誘発性ERK活性化機構におけるNOの関与2009
- Author(s)
  宮本嘉明、酒井亮祐、前田千春、神戸敏江、居原秀、渡邊泰男
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] カルモデュリンキナーゼIのS-グルタチオン化について2009
- Author(s)
  神戸敏江、高田剛、宮本嘉明、波多野直哉、渡邊泰男
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] タンパク質S-グルタチオン化による細胞シグナル制御2009
- Author(s)
  渡邊泰男
- Organizer
  日本学術振興会レドックス生命科学第170委員会第21回研究会
- Place of Presentation
  ホテルグリーンピア南阿蘇(熊本)
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] NO依存性レドックス制御によるニコチン・シグナリングの増強機構2009
- Author(s)
  宮本嘉明、酒井亮祐、神戸敏江、居原秀、渡邊泰男
- Organizer
  第9回日本NO学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] グルタチオン化によるカルモデュリンキナーゼIの活性制御2009
- Author(s)
  渡邊泰男、神戸敏江、宮本嘉明、波多野直哉
- Organizer
  第9回日本NO学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21500354
[Presentation] 活性システインパーサルファイドとS-ポリチオレーションが酸化ストレスを制御する
- Author(s)
  井田智章、澤　智裕、居原　秀、土屋幸弘、渡邊泰男、熊谷嘉人、末松　誠、本橋ほづみ、藤井重元、松永哲郎、山本雅之、Ming Xian、Jon M Fukuto、赤池孝章.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PLANNED-26111008
[Presentation] 活性イオウ分子種システインパースルフィドによる酸化ストレス制御
- Author(s)
  井田智章、澤　智裕、居原　秀、土屋幸弘、渡邊泰男、熊谷嘉人、本橋ほづみ、藤井重元、松永哲郎、Ming Xian、Jon M Fukuto、赤池孝章.
- Organizer
  第8回レドックス・ライフイノベーション第170委員会
- Place of Presentation
  シーガイアコンベンションセンター（宮崎市）
- Year and Date
  2014-08-21 – 2014-08-23
- Invited
- Data Source
  KAKENHI-PLANNED-26111008
[Presentation] 活性システインパーサルファイドによる酸化ストレス制御
- Author(s)
  井田智章、澤　智裕、居原　秀、土屋幸弘、渡邊泰男、熊谷嘉人、藤井重元、松永哲郎、Jon M Fukuto、赤池孝章.
- Organizer
  第67回日本酸化ストレス学会学術集会
- Place of Presentation
  同志社大学今出川キャンパス良心館（京都市上京区）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PLANNED-26111008

1. NIKI Ichiro (10262908)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. HIDAKA Hiroyoshi (80100171)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. OKAZAKI Katsuo (20252231)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MIZUTANI Akihiro (30242861)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YOKOKURA Hisayuki (90273242)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. NAITO Yasuhito (80303618)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. NOZAKI Naohito (70222198)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. Osuka Koji (40378013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
9. 高安正和 (60216794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. TSUCHIYA Yukihiro (30455406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
11. KAMBE Toshie (80276625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. MIYAMOTO Yoshiaki (20449101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
13. Akaike Takaaki (20231798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
14. HAGIWARA Masatoshi (10208423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKAKIBARA Zinsaku (70080182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IGUCHI Akihisa (20109763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKUMA Ichiro (40260393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HAYASHI Toshio (80303634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUBARA mamoru (90288481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Tokumitsu Hiroshi (20237077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 澤智裕 (30284756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
22. 朽津和幸 (50211884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 上原孝 (00261321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 井田智章 (70570406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
25. 石川彰彦 (10263617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 曲正樹 (50359882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SASTRY Mallika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. LUBIENSKI Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. POTTS Barbara C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. CHAZIN Walter J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. MEIJER Laurent

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. LUBIENSKI M

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. POTTS Barba

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. CHAZIN Walt

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. LAURENT Meij

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TSUTSUKI Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. IHARA Hideshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 高田剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 本橋ほづみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 西田基宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 藤井重元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 花岡健二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 臼田信光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Yasuo 渡辺 泰男

WATANABE Yasuo 渡邊 泰男

渡辺 泰男 ワタナベ ヤスオ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of cellular senescence via starvation-induced reactive sulfur species-signalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Redox regulation of calmodulin kinase I in neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of neuronal nitric oxide synthase via phosphorylation and dephosphorylation in neuronal cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure and function analyses of neuronal nitric oxide synthasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of activation mechanism of neuronal NO synthasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Watanabe Yasuo 渡辺泰男

WATANABE Yasuo 渡邊泰男

渡辺泰男ワタナベヤスオ

[Book] みてわかる薬学　図解　薬理学2015