WAKAO Hiroshi 若尾宏

… Alternative Names

若尾宏ワカオヒロシ

Less

Researcher Number	10280950
Affiliation (Current)	2025: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 獨協医科大学, 医学部, 教授 2016: 獨協医科大学, 医学部, 特任教授 2015: 北海道大学, 大学院医学研究科, 准教授 2012 – 2015: 北海道大学, 医学(系)研究科(研究院), 准教授 2013: 北海道大学, 大学院医学研究科, 准教授 … More 2011: 北海道大学, 医学(系)研究科(研究院), 助教 2007 – 2011: 北海道大学, 大学院・医学研究科, 助教 2006: 北海道大学, 大学院医学研究科, 助手 1996: 東京大学, 分子細胞生物学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Pathological medical chemistry Except Principal Investigator Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / 広領域 / Laboratory animal science / Basic Section 42040:Laboratory animal science-related / Basic Section 54040:Metabolism and endocrinology-related / Neurology
Keywords	Principal Investigator MAIT細胞 / 分化誘導 / CAR / 抗がん活性 / プロモーター / 細胞傷害活性 / がん抗原 / キメラ抗原受容体(CAR) / マウスiPS細胞 / 養子移入 … More / 抗がん / iPS細胞 / キメラ抗原受容体 / 生体防御能 / 加齢 / 自然免疫型T細胞 / 免疫能低下 / ２型自然リンパ球 / アルテルナリア / BALF / PAS染色 / Thサイトカイン / 新規マウスモデル / アレルギー / 2型自然リンパ球(ILC2) / 気道炎症 / 喘息 / セルソーティング / 酵素 / 好酸球性副鼻腔炎 / グループ２型自然リンパ球(ILC2) / 能性幹細胞 / 免疫制御能 / T細胞分化 / 胚性幹細胞 / サイトカイン / シグナル伝達 / 免疫制御性細胞 / レンチウイルスベクター / ES細胞 / 再生医学 / TCR / 免疫制御性T細胞 / 胚性幹(ES)細胞 … More Except Principal Investigator MAIT細胞 / 自然免疫型T細胞 / シグナル伝達 / RAS / STAT / 分化誘導 / サイトカイン / iPS細胞 / 中皮腫 / 細胞死 / 細胞増殖 / サイトカイン受容体 / アポトーシス / 造血因子 / 抗がん / 感染免疫 / signal transduction / JAK / 細胞分化 / 分化 / 造血 / 血液幹細胞 / iPS化 / 環境応答 / キナーゼ / Ras / ヒト / キメラ抗原受容体 / キメラ抗原受容体(CAR) / 呼吸器 / ウイルス感染 / マウスモデル / 生存期間延長 / 抗がん作用 / マウス / NK細胞 / リンパ腫 / 肺がん / 細胞傷害活性 / アゴニスト / MR1テトラマー / ガン転移 / 抗がん活性 / 肺がん細胞 / がん細胞治療 / 養子移入 / 糖尿病 / 褐色脂肪 / 脂肪細胞 / 脂肪組織褐色化 / 肝脂肪合成 / 脂肪肝 / 耐糖能異常 / 褐色化 / 脂肪組織 / 疾患モデル / 発生・分化 / 再生医学 / 細菌感染 / モデル動物 / innate T細胞 / ｉｎｎａｔｅＴ細胞 / 多発性硬化症 / 神経免疫 / cell death / cell differentiation / cell proliferation / hematopoietic growth factors / cytokines / 転写因子 / JAKキナーゼ / レトロウイルス / apoptosis / differentiation / hematopoiesis / cytokine receptors / cytokine / 増殖 / 造血細胞 / 幹細胞 / 誘導遺伝子 / 発生 / 血管内皮 / サイトカン受容体 / サイトカン / アカゲザル / 自然免疫系T細胞 / 動物モデル / T細胞分化誘導 / レンチウイルスベクター / さる胚性幹細胞 / NKT細胞 / 粘膜関連インバリアントT細胞 / ゲノム修飾のないiPS化 / 抗酸菌 / 抗菌活性 / 細胞治療 / 多剤耐性菌対策 / ES細胞 / 免疫制御性T細胞 / アスベスト / センダイ・ウイルス / 培養細胞 / 環境因子 / ストレス / 神経系 / 血小板 / 自然免疫 / ヘム代謝 / 情報伝達 / 遺伝子発現 / Caspase Less

自然免疫型T細胞MAIT細胞を用いた既製細胞医薬実現に向けた研究Principal Investigator
- Principal Investigator
  
  若尾宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Dokkyo Medical University
ヒトiPS細胞を用いた中皮腫治療基盤の確立
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Dokkyo Medical University
呼吸器ウイルス感染におけるMAIT細胞の炎症コントロール機能の解析
- Principal Investigator
  
  杉本智恵
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Dokkyo Medical University
自然免疫型T細胞を用いたがんの新たな細胞治療法開発Principal Investigator
- Principal Investigator
  
  若尾宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Dokkyo Medical University
高齢化社会における免疫能維持を目指してPrincipal Investigator
- Principal Investigator
  
  若尾宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Dokkyo Medical University
a study about the role of MAIT cells in the browning of white adipose tissue and the regulation of glucose metabolism
- Principal Investigator
  
  Usui Isao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Dokkyo Medical University
Towards the implementation of the cell theray for mesotherioma
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Dokkyo Medical University
MAIT cells in bacterial infection
- Principal Investigator
  
  Sugimoto Chie
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Dokkyo Medical University
Roles of innate immune cells in opportunistic infections
- Principal Investigator
  
  Sugimoto Chie
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University
innate T cells in multiple sclerosis
- Principal Investigator
  
  Hirotani Makoto
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Development of new protective method against environmental factors.
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Protection against Asbestosis.
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Analysis of signal transduction in a novel mouse model.Principal Investigator
- Principal Investigator
  
  WAKAO Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
ストレスの定量的評価の試み
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
ヒトは環境変動をどうとらえているのか?-環境検知機構の解明と応用の試み-
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
サイトカインによる造血細胞の増殖制御機構
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
サイトカインによるシグナル伝達機構の解析
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Institute of Molecular and Cellular Biosciencesa, The University of Tokyo
Control of cytokine function by modified signaling molecules
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Institute of Molecular and Cellular Biosciences, The University of Tokyo

[Book] Recent Advances in iPSC-derived cell type2020
- Author(s)
  Hiroshi WAKAO Chie Sigimoto
- Total Pages
  261
- Publisher
  Academicn press
- ISBN
  9780128222300
- Data Source
  KAKENHI-PROJECT-20K10435
[Journal Article] Potential of MAIT cells to modulate asthma2024
- Author(s)
  Shimizu Yasuo、Sugimoto Chie、Wakao Hiroshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 40-47
- DOI
  10.1016/j.alit.2023.07.006
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19732, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
[Journal Article] Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells2024
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  Biomedicines
  
  Volume: 12 Issue: 1 Pages: 137-137
- DOI
  10.3390/biomedicines12010137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K09654, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
[Journal Article] A flow-cytometry-based assay to assess the cytolytic activity against tumor cells by combination of mouse MAIT cells and natural killer cells2023
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 4 Pages: 102620-102620
- DOI
  10.1016/j.xpro.2023.102620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
[Journal Article] Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activit2022
- Author(s)
  Chie Sugimoto, Yukie Murakami, Eisuke Ishii, Hiroyoshi Fujita, Hiroshi Wakao
- Journal Title
  
  eLife
  
  Volume: 11
- DOI
  10.7554/elife.70848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-21K19732
[Journal Article] Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation2022
- Author(s)
  Shimizu Yasuo、Horigane-Konakai Yukiko、Ishii Yoshii、Sugimoto Chie、Wakao Hiroshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1005226-1005226
- DOI
  10.3389/fimmu.2022.1005226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19732, KAKENHI-PROJECT-23K23806
[Journal Article] Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy2022
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 12 Pages: 3160-3160
- DOI
  10.3390/biomedicines10123160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K23806
[Journal Article] iPSC-derived mucosal-associated invariant T cells2021
- Author(s)
  Wakao Hiroshi、Sugimoto Chie
- Journal Title
  
  Recent Advances in iPSC-Derived Cell Types, Volume 4 in Advances in Stem Cell Biology
  
  Volume: 4 Pages: 31-47
- DOI
  10.1016/b978-0-12-822230-0.00012-0
- ISBN
  9780128222300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03565
[Journal Article] Mucosal-Associated Invariant T Cells in Regenerative Medicine2017
- Author(s)
  Wakao Hiroshi、Sugimoto Chie、Kimura Shinzo、Wakao Rika
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 8 Pages: 1-11
- DOI
  10.3389/fimmu.2017.01711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03565
[Journal Article] Epigenetic silencing of V(D)J recombination is a major determinant for selective differentiation of mucosal-associated invariant t cells from induced pluripotent stem cells.2017
- Author(s)
  Yutaka Saito, Chie Sugimoto, Toutai Mituyama and Hiroshi Wakao
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 3 Pages: e0174699-e0174699
- DOI
  10.1371/journal.pone.0174699
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430084, KAKENHI-PROJECT-15K16089
[Journal Article] The dynamics of mucosal-associated invariant T cells in multiple sclerosis2016
- Author(s)
  Chie Sugimoto, Makoto Hirotan, Kazunori Yoshikiyo, Uichi Koshimizu, Rika Wakao, Takahiro Horinouchi, Yuichi Mazaki, Tsunehiko Higashi, Toshiyuki Fukazawa, Hiroyoshi Fujita, Hidenao Sasaki and Hiroshi Wakao
- Journal Title
  
  SpringerPlus
  
  Volume: 5 Issue: 1 Pages: 1259-1259
- DOI
  10.1186/s40064-016-2923-9
- NAID
  120005906931
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430084, KAKENHI-PROJECT-26860166
[Journal Article] Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.2015
- Author(s)
  Sugimoto C, Konno T, Wakao R, Fujita H, Fujita H, Wakao H
- Journal Title
  
  PLOS ONE
  
  Volume: 10
- NAID
  120005611266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430084
[Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs2013
- Author(s)
  H Wakao and H Fujita
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Pages: 2341-2342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu et al. and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation.2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390119
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390119
[Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs.2013
- Author(s)
  H Wakao and H Fujita
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Pages: 2341-2342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Differentiation of iNKT cells from embryonic stem cells.2010
- Author(s)
  若尾宏
- Journal Title
  
  Curr.Immunol.Rev. 6(2)
  
  Pages: 102-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] Constitutively active Stat5A and Stat5B promote adipogenesis.2010
- Author(s)
  Wakao H., Wakao, R, Oda, A., Fujita, H.
- Journal Title
  
  Environmental Health and Preventive Medicine In press
- NAID
  10029520575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] Regulation of ghrelin signaling by a leptin-induced gene, negative regulatory element-binding protein, in the hypothalamic neurons.2010
- Author(s)
  Komori, T., Doi, A., Furuta, H., Wakao, H., Nakao, N., Nakazato, M., Nanjo, K., Senba, E., Morikawa, Y.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 37884-37894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] Regulation of ghrelin signaling by a leptin-induced gene, negative regulatory element-binding protein, in the hypothalamic neurons.2010
- Author(s)
  Komori T, Doi A, Furuta H, Wakao H., Nakao N, Nakazato M, Nanjo K, Senba E, Morikawa Y.
- Journal Title
  
  J Biol Chem. 285(48)
  
  Pages: 37884-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] Differentiation of iNKT cells from embryonic stem cells2010
- Author(s)
  Hiroshi WAKAO
- Journal Title
  
  Current Immunology Reviews (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] Constitutively active Stat5A and Stat5B promote adipogenesis2010
- Author(s)
  Wakao H, Wakao R, Oda A, Fujita H.
- Journal Title
  
  Environ.Health.Prev.Med.
  
  Volume: (In press)
- NAID
  10029520575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] 末梢リンパ球の全能性とその応用生化学2009
- Author(s)
  若尾宏
- Journal Title
  
  日本生化学会 81
  
  Pages: 277-289
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] NKT cells: from totipotency to regenerative medicine.2009
- Author(s)
  若尾宏
- Journal Title
  
  Arch Immunol Ther Exp (Warsz). 57(2)
  
  Pages: 117-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] 末梢リンパ球の全能性とその応用2009
- Author(s)
  若尾家
- Journal Title
  
  生化学 (印刷中)
- NAID
  10024916393
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] 抹消リンパ球の全能性とその応用2009
- Author(s)
  若尾宏
- Journal Title
  
  生化学 81
  
  Pages: 277-289
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] NKT cells ; from totipotency to regenerative medicine2009
- Author(s)
  若尾宏
- Journal Title
  
  Arch. Immunol. Ther. Exp. 57
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] induction of natural killer T cell from embryotic stem cells prepared by somatic cell nuclear transfer2008
- Author(s)
  Wakao H, Wakao R, et.al.
- Journal Title
  
  FASEB J. 22
  
  Pages: 2223-2231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659147
[Journal Article] In vitro induction of natural killer T cells from embryonic stem cells prepared using somatic cell nuclear transfer.2008
- Author(s)
  若尾宏, Wakao R, Sakata S, Iwabuchi K, Oda A, Fujita H.
- Journal Title
  
  FASEB J. 22(7)
  
  Pages: 2223-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590299
[Journal Article] induction of natural killer T cell from embryotic stem cells prepared by somatic cell nuclear transfer2008
- Author(s)
  Wakao H, Wakao R, et al
- Journal Title
  
  FASEB J. 22
  
  Pages: 2223-2231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659147
[Journal Article] A novel mouse model for iNKT cell study2007
- Author(s)
  Wakao H, Kawamoto H, et al
- Journal Title
  
  J Immunol. 179
  
  Pages: 3888-3895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659147
[Journal Article] The importance of CD25(+)CD4(+) regulatory T cells in mouse hepatic allograft tolerance.2006
- Author(s)
  Jiang X, Wakao H et al.
- Journal Title
  
  Liver Transpl 12
  
  Pages: 1112-1118
- Data Source
  KAKENHI-PROJECT-17659173
[Patent] マウスMAIT様細胞ならびにMAIT細胞豊富なマウス作製とその利用2019
- Inventor(s)
  若尾宏、杉本智恵
- Industrial Property Rights Holder
  獨協医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H03565
[Patent] MAIT-like cells and method for manufacturing same.2013
- Inventor(s)
  若尾宏，藤田博美、小清水右一，由清和則
- Industrial Property Rights Holder
  若尾宏，藤田博美、小清水右一，由清和則
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-30
- Acquisition Date
  2014-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-23659324
[Patent] MAIT 様細胞およびその作成方法2012
- Inventor(s)
  若尾宏,小清水右一、吉清和則、藤田博美
- Industrial Property Rights Holder
  若尾宏,小清水右一、吉清和則、藤田博美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-239195
- Filing Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-23659324
[Patent] MAIT 様細胞およびその作製方法2012
- Inventor(s)
  若尾宏、小清水右一、吉清和則、藤田博美
- Industrial Property Rights Holder
  若尾宏、小清水右一、吉清和則、藤田博美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-239195
- Filing Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] Novel mouse models for studying the functions of MAIT cells2024
- Author(s)
  若尾　宏　杉本　智恵
- Organizer
  CD1d-MR1 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25181
[Presentation] Novel animal models to explore functions of MAIT cells2024
- Author(s)
  Chie Sugimoto, Hiroshi Wakao
- Organizer
  CD1 MR1 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23806
[Presentation] 新規MAIT細胞研究用マウスモデルの確立2020
- Author(s)
  杉本　智恵　若尾　宏
- Organizer
  先端モデル動物支援プラットフォーム
- Data Source
  KAKENHI-PROJECT-20K10435
[Presentation] 加齢による粘膜関連インバリアントT細胞の表現系の変化2017
- Author(s)
  杉本智恵、佐々木秀直、若尾宏
- Organizer
  第87回日本衛生学会
- Place of Presentation
  フェニックスシーガイアリゾート（宮崎県・宮崎市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] MAIT細胞の機能解析のための実験モデル2017
- Author(s)
  杉本智恵、若尾宏
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17H03565
[Presentation] iPS細胞からの自然免疫型T細胞分化誘導の分子機序の統合的解析2016
- Author(s)
  若尾宏、杉本智恵、満山統泰、斎藤裕
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] iPS細胞からのヒト自然免疫型T細胞大量産生系の確立2015
- Author(s)
  杉本智恵、若尾宏
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] エイズ患者での日和見感染発症における自然免疫系細胞の重要性と新規バイオマーカーの検索2014
- Author(s)
  杉本智恵、若尾宏、藤田博美
- Organizer
  日本衛生学会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2014-05-27
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] HIV感染者での日和見感染症発症における自然免疫系細胞の重要性2014
- Author(s)
  杉本智恵、若尾宏、藤田博美
- Organizer
  日本生化学会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
- Organizer
  15^<th> International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] ガン化のおそれのないiPS 細胞の開発2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] ガン化のおそれのないヒトiPS細胞作製の試み2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学・金沢美術工芸大学（金沢市）
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
- Organizer
  15^<th> International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] ガン化の恐れのないヒトiPS細胞作製の試み2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢美術工芸大学（金沢市）
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] Constitutively active Stat5a and Stta5b promote adipogenesis2011
- Author(s)
  若尾宏
- Organizer
  cytokine receptors and their Stat-mediated mechanisms of action
- Place of Presentation
  GEORG SPEYER HAUS (Germany)(招待講演)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] Constitutively active Stat5a and Stta5b promote adipogenesis2011
- Author(s)
  若尾　宏
- Organizer
  cytokine receptors and their Stat-mediated mechanisms of action(招待講演)
- Place of Presentation
  GEORG SPEYER HAUS(Germany)
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] A novel mouse model and the differentiation of T lymphocytes from ES cells2008
- Author(s)
  若尾宏
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド, 神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20590299

1. FUJITA Hiroyoshi (60142931)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. Sugimoto Chie (60469955)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
3. ODA Atsushi (50255436)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
4. MIYAJIMA Atsushi (50135232)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HARA Takahiko (80280949)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KINOSHITA Taisei (40301113)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SAITO Takeshi (40153811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OHTSUKI Takemi (40160551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Hirotani Makoto (60399920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SASAKI HIDENAO (80281806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Usui Isao (50377272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 漆原範子 (80396308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤坂志帆 (30512082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森一泰 (20270655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 布矢純一 (40466842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KURODA Marcelo J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WAKAO Hiroshi 若尾 宏

若尾 宏 ワカオ ヒロシ

Research Projects

Research Products

Co-Researchers

自然免疫型T細胞MAIT細胞を用いた既製細胞医薬実現に向けた研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自然免疫型T細胞を用いたがんの新たな細胞治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高齢化社会における免疫能維持を目指してPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of signal transduction in a novel mouse model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

WAKAO Hiroshi 若尾宏

若尾宏ワカオヒロシ