Chou Kyokukou 張旭紅

… Alternative Names

張旭紅チヨウキヨクコウ

ZHANG Xuhong 張旭紅

ZHANG Zuhong 張旭紅

Less

Researcher Number	10292442
Other IDs
Affiliation (Current)	2025: 山形大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 山形大学, 大学院医学系研究科, 助教 2020 – 2023: 山形大学, 大学院医学系研究科, 助教 2014: 山形大学, 大学院医学系研究科, 助教 2013 – 2014: 山形大学, 医学(系)研究科(研究院), 助教 2012: 山形大学, 医学系研究院, 助教 1998 – 2006: YAMAGATA UNIVERSITY SCHOOL OF MEDICINE,DEPARTMENT OF BIOCHEMISTRY,INSTRUCTOR, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Functional biochemistry / Basic Section 53030:Respiratory medicine-related / Functional biochemistry / Structural biochemistry / Gastroenterology / Living organism molecular science
Keywords	Principal Investigator microRNA / 核酸外用薬 / 核酸薬外用薬 / miRNA / 口腔癌 Except Principal Investigator CO / ヘムオキシゲナーゼ / ビリベルジン / ビリルビン / ヘムの分解 … More / 酸素活性化機構 / 酵素活性化 / Hmu O / 酵素活性化機構 / ヘム / Corynebacterium diphtheriae / ジフテリア菌 / シアノバクテリア / ベルドヘム / BILIVERDIN / OXYGEN ACTIVATION / HEME OXYGENASE / ビリベルジン還元酵素 / Heme oxygenase / ピリルビン / 細菌のヘム分解酵素 / オキシゲナーゼ / 非小細胞肺癌 / CTOS作製 / 長鎖非コードRNA / スフェロイド / オルガノイド / 肺癌 / lncRNA / Soybean, GmHO-1 / Cyanobacterium / Biliverdin / Verdoheme / Hydroxyheme / Oxygen activation / ショウジョウバエ / 過酸化水素 / 鉄 / ピリベルジン / 大豆ヘムオキシゲナーゼ / ヒドロキシヘム / 酸素活性化 / CYANOBACTERIUM / VERDOHEME / meso-HYDROXYHEME / HYDROPEROXO SPECIES / メソヒドロキシヘム / ヒドロペルオキソ / BILIRUBIN / BILIVERDIN REDUCTASE / INTERMEDIARY STEP / HEME DEGRADATION / ピリペルジン / 中間過程 / ヘム分解 / Bilirubin / biliverdin / Activation of oxygen / Heme degradation enzyme / Heme degradation / オキシグナーゼ / ヘムオキシグナーゼ / HmuO / 肝がん / 診断マーカー / 分子標的治療 / microRNA / 肝癌 / 環境変化 / 反応調節 / 環境応答機構 / ESI-MSによる逐次反応速度論解析 / 酸性化環境への適応 / 酸素消費の速度論解析 / 酵素活性の微調節 Less

口腔癌治療用RNA医薬のDDS最適化研究Principal Investigator
- Principal Investigator
  
  張旭紅
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Yamagata University
Development of a microRNA-based drug against oral cancerPrincipal Investigator
- Principal Investigator
  
  張旭紅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
Attempt to establish a novel therapeutic approach targeting long non-coding RNAs for EGFR-TKI-resistant lung cancer
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Yamagata University
A translational research on miR-224: towards novel diagnostic and therapeutic approach for hepatocellular carcinoma
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Heme oxygenase strategy for circumventing environmental changes_fine tuning of activity
- Principal Investigator
  
  MIGITA Taiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Yamaguchi University
Mechanism of heme degradation by heme oxygenase and diversity of heme oxygenase among the various organisms
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yamagata University
Mechanism of heme degradation by heme oxygenase and the interaction of heme
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yamagata University
Relation between the structure and the oxygen acitivation of heme oxygenase reaction
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  YAMAGATA UNIVERSITY
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yamagata University
Mechanism of heme degradation by heme oxygenase
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Structural biochemistry
- Research Institution
  YAMAGATA UNIVERSITY
Molucular mechanisms of oxygen activation at the three steps in heme oxygenase reaction
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  YAMAGATA UNIVERSITY

All 2023 2022 2021 2020 2013 2012 2011 2005 2004 Other

All Journal Article Presentation

[Journal Article] Protein expresses ey The ho2 gene of the cyane-lacterium Synechocystis sp. pcc 68a3 is a true2005
- Author(s)
  Zhang Xuhong
- Journal Title
  
  FEBS Journal 272
  
  Pages: 1012-1022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC6803 is a true heme oxygenase2005
- Author(s)
  Zhang X. et al.
- Journal Title
  
  FEBS J. 272
  
  Pages: 1012-1022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp.PCC 6803 is a true heme oxygenase2005
- Author(s)
  Zhang Xuhong
- Journal Title
  
  FEBS Journal 272
  
  Pages: 1012-1022
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied2004
- Author(s)
  Zhang Xuhong
- Journal Title
  
  European Journal of Biochemistry 271
  
  Pages: 1713-1724
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique feature of recompinant heme oxggenase of Drosophila melanegaster comparea with2004
- Author(s)
  Zhang Xuhong
- Journal Title
  
  European Journal of Biochemietry 271
  
  Pages: 1713-1724
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenase studied2004
- Author(s)
  Zhang X. et al.
- Journal Title
  
  Eur.J.Biochem 271
  
  Pages: 1713-1724
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Presentation] miR-223を用いた口腔がんに対する新規RNAベース治療法の確立に関する研究2023
- Author(s)
  邵力, 張旭紅, 千田邦明, 伊藤吏, 橘寛彦, 惣宇利正善, 今田恒夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 治療用RNAスクリーニングのプラットフォームとしての患者由来腫瘍オルガノイドの確立における課題2023
- Author(s)
  邵力、張旭紅、鈴木潤、渡辺光、塩野知志、千田邦明、伊藤吏、惣宇利正善、今田恒夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] miR-223を用いた口腔がんに対する新規RNAベース治療法の確立に関する研究2023
- Author(s)
  邵力、張旭紅、千田邦明、伊藤吏、橘寛彦、惣宇利正善、今田恒夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] 治療用RNAのスクリーニングのための患者由来の腫瘍オルガノイドの確立における課題2023
- Author(s)
  邵力, 張旭紅, 鈴木潤, 渡辺光, 塩野知志, 千田邦明, 伊藤吏, 惣宇利正善, 今田恒夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 薬物反応試験のための患者由来の肺癌オルガノイドモデルの構築2022
- Author(s)
  邵力、張旭紅、鈴木潤、高森聡、塩野知志、惣宇利正善、今田恒夫.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 薬物反応試験のための患者由来の肺癌オルガノイドモデルの構築2022
- Author(s)
  邵力、張旭紅、鈴木潤、高森聡、塩野知志、惣宇利正善、今田恒夫
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] ゲフィチニブ耐性非小細胞肺がん細胞株におけるlncRNA S180122の発現亢進と上皮間葉転換の促進2021
- Author(s)
  1.邵力、張旭紅、鈴木潤、鈴木克幸、高森聡、大泉弘幸、惣宇利正善、今田恒夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] Establishment of Patient-Derived Oral Cancer Organoid Cultures.2020
- Author(s)
  2.Tachibana H, Sho R, Zhang XH, Ozaki H, Koike S, Karakami K, Konta T.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] LncRNA S180122 modulates EMT in human non-small cell lung cancer cells.2020
- Author(s)
  Sho R, Zhang XH, Suzuki J, Osaki T, Souri M, Konta T.
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] Is microRNA-224 a potential therapeutic target for HCC?2013
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] Identification of miR-224 target genes and pathways related to hepatocellular carcinoma2012
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] The Use of RNAi-based Screens to Identify Host Factors Involved in HCV Replication2012
- Author(s)
  Sho R, Zhang XH, Watanabe H, et al
- Organizer
  The 10th JSH Single Topic Conference “Hepatitis C:Best Practice Based on Science”
- Place of Presentation
  KEIO PLAZA HOTEL (Shinjuku, Tokyo)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] 反応環境に応答したヘムオキシゲナーゼによるヘム分解の微調整2011
- Author(s)
  高田さゆり・佐藤道比古・張旭紅・右田たい子
- Organizer
  日本生物物理学会第49回年会
- Place of Presentation
  兵庫県立大学姫路書写キャンパス(姫路市)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] Fine tuning of the heme catabolism by heme oxygenase in response to the reaction milieu2011
- Author(s)
  高田さゆり・佐藤道比古・張極紅・右田たい子
- Organizer
  日本生物物理学会第49回年会
- Place of Presentation
  兵庫県立大書写キャンパス(姫路市)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性2011
- Author(s)
  高田さゆり・張旭紅・佐藤道比古・右田たい子
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学大学会館(つくば市)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性2011
- Author(s)
  高田さゆり・張極紅・佐藤道比古・右田たい子
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学(つくば市)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヒト肝癌細胞異種移植モデルを用いたantagomiR-224の抗腫瘍活性の検討
- Author(s)
  邵力,張旭紅, 福田直樹等
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都, 京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590953

1. YOSHIDA Tadashi (10004673)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. MIGITA Taiko (90159161)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. SATO Michihiko (00135344)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. SHO Ri (80344787)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. FUJII Hiroshi (80228957)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OZAKI Shinichi (40280581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIGITA Kouto (90116757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. WATANABE Hisayoshi (00332536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. ISHII Rika (60466612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木潤 (70533925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 濱田顕 (80772954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 千田邦明 (20571665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. OLSOH John S

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Chou Kyokukou 張 旭紅

張 旭紅 チヨウ キヨクコウ

ZHANG Xuhong 張 旭紅

ZHANG Zuhong 張 旭紅

Research Projects

Research Products

Co-Researchers

口腔癌治療用RNA医薬のDDS最適化研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a microRNA-based drug against oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Protein expresses ey The ho2 gene of the cyane-lacterium Synechocystis sp. pcc 68a3 is a true2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC6803 is a true heme oxygenase2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp.PCC 6803 is a true heme oxygenase2005

Author(s)

Journal Title

Data Source

[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied2004

Author(s)

Journal Title

Chou Kyokukou 張旭紅

張旭紅チヨウキヨクコウ

ZHANG Xuhong 張旭紅

ZHANG Zuhong 張旭紅