inobe manabu 猪部学

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INOBE Manabu 猪部学

猪部学イノベマナブ

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Researcher Number	10312414
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, 福岡薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 国際医療福祉大学, 福岡薬学部, 教授 2020 – 2021: 国際医療福祉大学, 福岡薬学部, 教授 2013 – 2019: 金沢大学, 薬学系, 准教授 2001: 北海道大学, 遺伝子病制御研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Risk sciences of radiation and chemicals / Basic Section 63020:Radiation influence-related / Experimental pathology / Tumor therapeutics
Keywords	Principal Investigator HVEM Except Principal Investigator 低分子化合物 / 阻害剤 / ヌクレオチド除去修復 / ケミカルバイオロジー / シスプラチン / DNA損傷プローブ / 近位依存性ビオチン標識法 / タンパク質分解誘導剤 / 薬学 … More / 遺伝子 / 遺伝学 / 癌 / 癌治療 / オラパリブ / caspase / steroid / Transgenic mice / Apoptosis / Thymocyte / カスペース / ステロイド / 遺伝子導入マウス / アポトーシス / 胸腺細胞 / 増感作用 / 抗癌剤 / スクリーニング / 化合物ライブラリー Less

新規免疫チェックポイント分子HVEMによるB細胞の制御機構Principal Investigator
- Principal Investigator
  
  猪部学
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  International University of Health and Welfare
Chemical approaches to understand the complex mechanism of nucleotide excision repair
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kanazawa University
Mechanistic analysis of novel DNA repair inhibitors and their possible application to anticancer therapy
- Principal Investigator
  
  Matsunaga Tsukasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Application of chemical biology to a mechanistic study of human nucleotide excision repair
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Analysis of a novel small-molecule compound inducing the degradation of a cisplatin resistance-related factor ERCC1
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
Molecular analysis of steroid-induced apoptosis and its relevance to disease pathogenesis.
- Principal Investigator
  
  UEDE Toshimitsu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hokkaido University

All 2021 2017 2015 2014

All Journal Article Presentation

[Journal Article] CD28 confers CD4+ T cells with resistance to cyclosporin A and tacrolimus but to different degrees.2021
- Author(s)
  Kawai, H., Yagyu, F., Terada, A. et al.
- Journal Title
  
  Asian Pac J Allergy Immunol.
  
  Volume: -
- DOI
  10.12932/ap-270820-0949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12319, KAKENHI-PROJECT-19H04265
[Journal Article] Rapid G0/1 transition and cell cycle progression in CD8+ T Cells compared to CD4+ T Cells following in vitro stimulation2017
- Author(s)
  Mishima, T., Fukaya, S., Toda, S., Ando, Y., Matsunaga, T. and Inobe, M.
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 印刷中 Issue: 5 Pages: 168-175
- DOI
  10.1111/1348-0421.12479
- NAID
  120006343955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02952, KAKENHI-PROJECT-16K15118
[Journal Article] Concanavalin A-mediated T cell proliferation is regulated by Herpes Virus Entry Mediator costimulatory molecule.2014
- Author(s)
  Ando, Y., Yasuoka, C., Mishima, T., Ikematsu, T., Uede, T., Matsunaga, T. and Inobe, M.
- Journal Title
  
  In Vitro Cell. Dev. Biol.- Animal
  
  Volume: 50 Issue: 4 Pages: 313-320
- DOI
  10.1007/s11626-013-9705-2
- NAID
  120005349169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510068, KAKENHI-PROJECT-25281017, KAKENHI-PROJECT-25640089
[Journal Article] Rapid proliferation of activated lymph node CD4+ T Cells is achieved by eliminating gap phases in cell cycle progression.2014
- Author(s)
  Mishima, T., Toda, S., Ando, Y., Matsunaga, T. and Inobe, M.
- Journal Title
  
  Cell. Mol. Biol. Lett.
  
  Volume: 19 Issue: 4 Pages: 638-648
- DOI
  10.2478/s11658-014-0219-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510068, KAKENHI-PROJECT-25281017, KAKENHI-PROJECT-25640089
[Journal Article] Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells2014
- Author(s)
  Mitsuo Wakasugi, Takuma Sasaki, Megumi Matsumoto, Miyuki Nagaoka, Keiko Inoue, Manabu Inobe, Katsuyoshi Horibata, Kiyoji Tanaka, and Tsukasa Matsunaga
- Journal Title
  
  J. Biological Chemistry
  
  Volume: 289 Issue: 41 Pages: 28730-28737
- DOI
  10.1074/jbc.m114.589747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22131009, KAKENHI-PROJECT-24510068, KAKENHI-PROJECT-25281017, KAKENHI-PROJECT-25640089, KAKENHI-PROJECT-26870867
[Presentation] Activation of ATR and ATM signaling pathways by NER-dependent secondary damage in mammalian quiescent cells2015
- Author(s)
  Wakasugi, M., Sasaki, T., Matsumoto, M., Nagaoka, M., Inoue, K., Inobe, M., Horibata, K., Tanaka, K. and Matsunaga, T.
- Organizer
  The 15th International Congress of Radiation Research
- Place of Presentation
  国立京都国際会館
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281017
[Presentation] ヌクレオチド除去修復因子ERCC1を分解誘導する新規化合物の抗がん剤作用増強効果2015
- Author(s)
  中家裕美子、和田奈巳、西村陽平、若杉光生、猪部　学、遠藤良夫、松永　司
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山大学
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-25281017

1. MATSUNAGA Tsukasa (60192340)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. WAKASUGI Mitsuo (80345595)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. GOTO Kyoko (50180245)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KUNISHIMA Munetaka (10214975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ODA Akifumi (50433511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NISHINAGA Mari (10646681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ENDO Yoshio (30211783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KON Shigeyuki (90344499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 向智里 (70143914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松浦顕教 (50836096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田中亀代次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

inobe manabu 猪部 学

INOBE Manabu 猪部 学

猪部 学 イノベ マナブ

Research Projects

Research Products

Co-Researchers

新規免疫チェックポイント分子HVEMによるB細胞の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemical approaches to understand the complex mechanism of nucleotide excision repair

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanistic analysis of novel DNA repair inhibitors and their possible application to anticancer therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of chemical biology to a mechanistic study of human nucleotide excision repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of a novel small-molecule compound inducing the degradation of a cisplatin resistance-related factor ERCC1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of steroid-induced apoptosis and its relevance to disease pathogenesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CD28 confers CD4+ T cells with resistance to cyclosporin A and tacrolimus but to different degrees.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid G0/1 transition and cell cycle progression in CD8+ T Cells compared to CD4+ T Cells following in vitro stimulation2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Concanavalin A-mediated T cell proliferation is regulated by Herpes Virus Entry Mediator costimulatory molecule.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Rapid proliferation of activated lymph node CD4+ T Cells is achieved by eliminating gap phases in cell cycle progression.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Activation of ATR and ATM signaling pathways by NER-dependent secondary damage in mammalian quiescent cells2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヌクレオチド除去修復因子ERCC1を分解誘導する新規化合物の抗がん剤作用増強効果2015

Author(s)

Organizer

Place of Presentation

Year and Date

inobe manabu 猪部学

INOBE Manabu 猪部学

猪部学イノベマナブ